studium 0.18.7

data/lib/studium/exam_topics/cellbiology

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+# =========================================================================== #
+# === Cellbiology Tag
+#
+# Cellbio tag. Cell Tag. Cel tag. Zell Tag. Celltag. Zellbiologie tag.
+# Zellbio tag. Akt tag. Aktuell tag.
+# Cell2 tag (wird eventuell später geändert).
+# Zellbiologie tierischer Zellen.
+#
+# Alles über den Zellzyklus wird in einer separaten Datei gesammelt.
+# =========================================================================== #
+
+- Wenn <one>eine Zellmembran nur bestimmte Ionen durchlässt</one>, <two>wie nennen wir dieses Phänomen</two>? <one>Selektive Permeabilität</one>. URL: https://de.wikipedia.org/wiki/Selektive_Permeabilit%C3%A4t []
+- What is meant with the abbreviation <one>Tyr-P</one>? This refers to <one>a phosphorylated tyrosine</one>. URL: https://en.wikipedia.org/wiki/Tyrosine []
+- <one>Which three main pathways</one> are <two>involved in autophagy</two>? (1) Macroautophagy (2) <one>Microautophagy</one> (3) <one>Chaperone-mediate autophagy (CMA)</one>
+- The <one>cell's library</one> is ... ? <one>DNA</one>. []
+- Which <one>cellular phenomenon</one> <two>was first discovered</two> in <three>C. elegans</three>? <one>Apoptosis</one>. URL: https://en.wikipedia.org/wiki/Apoptosis []
+- Wofür steht die Abkürzung <one>ERES</one> in der Zellbiologie? <one>ER export sites</one>. URL: https://pubmed.ncbi.nlm.nih.gov/30304445/ []
+- <one>Wo</one> genau spalten die <two>Caspasen</two>? Spezifisch <one>hinter</one> <two>Aspartatresten</two>. URL: https://de.wikipedia.org/wiki/Caspasen []
+- <one>Wo</one> spalten <two>Caspasen</two>? <one>Hinter</one> einem <two>Aspartat</two>. URL: https://de.wikipedia.org/wiki/Caspasen []
+- <one>Taxol</one> <two>bindet an welche Tubulin-Form</two>? <one>Taxol</one> bindet an <two>Beta-Tubulin</two>, <two>anstelle von GTP</two>. URL: https://de.wikipedia.org/wiki/Paclitaxel []
+- Das <one>Zellweger-Syndrom</one> beruht auf ...? <one>Mutationen in den Genen</one>, <two>die für die Entstehung von Peroxisomen erforderlich sind</two>.
+- <one>Hohe Apertur</one>, <two>niedrige Auflösung</two>? <one>Nein</one>! <two>Hohe Apertur</two>, <three>gute Auflösung</three>. []
+- In der Zellbiologie: was heißt <one>ICAM</one>? <one>Intercellular adhesion molecule</one>. URL: https://en.wikipedia.org/wiki/Intercellular_adhesion_molecule
+- <one>FtsZ</one> ähnelt in Eukarya was? <one>Tubulin</one>. URL: https://de.wikipedia.org/wiki/Zellteilungsprotein_FtsZ []
+- <one>Durchmesser</one> eines <two>clathrin triskelion polyhedral lattice</two>? <one>80nm</one>. []
+- Die <one>RNA Helicasen</one> können im zellulären Kontext was machen? Sie können <one>RNA binding proteins</one> von der RNA lösen.
+- Durch <one>Anreicherung nicht abbaufähiger Materialien in der Zelle</one> entstehen ...? <one>Residualkörper</one>. []
+- <one>Dynamin</one> <two>uses which energy source</two>? <one>GTP</one>. URL: https://en.wikipedia.org/wiki/Dynamin []
+- How is the <one>interior of the ER</one> called? <one>lumen</one> - <two>ER lumen</two>. []
+- Andere Bezeichnung für <one>three-layered</one>? <one>Trilaminar</one>. URL: https://en.wiktionary.org/wiki/trilaminar []
+- Bis etwa 1970 wurde in der Cytologie das <one>Feulgen reagent</one> verwendet. Welche Farbe hat dies? Ein <one>dunkles rot</one>.
+- Nenne <one>drei Vertreter</one> des <two>Endomembransystems</two>. A: (1) <one>Golgi</one> (2) <one>Endoplasmatisches Retikulum</one> (3) <one>Lysosom</one>
+- A <one>cell</one> <two>becomes committed by a process called ... </two>? <one>Determination</one>. []
+- <one>Ferroptosis</one> is <two>a type of programmed cell death</two>. <three>In this type, we can see the accumulation of ... </three>? <one>lipid peroxides</one>. TODO: ADD MISSING URL HERE.
+- Durchmesser der <one>Porine</one>? <one>1 nm</one>. URL: https://de.wikipedia.org/wiki/Porine
+- Wie kann <one>Autophagie</one> (ein <two>degradation process</two>) <three>induziert werden</three>? Durch <one>Hungern</one> (= <two>starvation</two>).
+- In microscopy: what are <one>chromophore groups</one>? <one>Groups</one> <two>with conjugated double bonds</two> that give the dye its color.
+- <one>Why</one> do the <two>osteoclasts</two> need <three>acid</three>? <one>Acid</one> helps osteoclasts <two>dissolve the bone minerals</two>.
+- <one>Glucose transport</one> <two>in a cell</two> <three>is connected to which gradient</three>? <one>Na⁺ Gradient</one>.
+- Die Synthese <one>cytoplasmatischer Proteine</one> erfolgt ...? An <one>nichtmembran-assoziierten Ribosomen</one>.
+- What is <one>negative staining</one>? The <one>background</one> <two>but not the cell</two> <one>is stained</one>. Unstained cells appear as bright objects against a dark background.
+- In cellbiology: we may see something called <one>Endo H</one>. <two>What is this</two>? This is the enzyme <one>Endoglycosidase H</one>.
+- <one>COPII-coated vesicles</one> <two>go from→to</two>? From <one>ER → Golgi</one>.
+- <one>How much</one> of the <two>ER</two> comprises of <three>newly-synthesized proteins</three>? Only about <one>1%</one>.
+- In der Zellbiologie: was heißt <one>ERGIC</one>? <one>ER-Golgi intermediate compartment</one>.
+- Was ist die <one>Glykokalyx</one>? Die Gesamtheit der Zuckerketten an der extrazellulären Zelloberfläche.
+- Give <one>two hormone-examples</one> <two>for vesicular proteins</two>. A: (1) <one>insulin</one> (2) erythropoietin (EPO)
+- In der Zellbiologie: was ist das <one>Retromer</one>? Das <one>Retromer</one> ist ein Komplex an Proteinen die wichtig sind für die Wiederverwendung von <two>transmembrane receptors</two>, von Endosomen hin zum trans-Golgi network (TGN).
+- <one>Rab Proteins</one> <two>are anchored on two cysteins in their C-terminus</two> <three>through which group</three>? Through <one>prenyl groups</one>.
+- In cellbiology: what is an <one>organotypic culture</one>? This is the case when cells are grown in a <one>three-dimensional (3-D) environment</one>.
+- Was ist mit dem Begriff <one>zelluläre Proteinsortierung</one> gemeint? Wenn die Zelle <one>unterscheidet</one> wohin ein Protein geschickt werden soll.
+- Was heißt <one>EDTA</one> und wozu setzt man es in der Zellbiologie ein? <one>EDTA</one> heißt <two>Ethylendiamintetraacetid acid</two>. Es bindet Ca2⁺ Ionen, die wiederum für Zell-Zell Adhesionskontakte wichtig sind. Das Zell-Gewebe kann daraufhin leichter getrennt werden.
+- Name <one>three</one> <two>biogenesis strategies</two> for making a new organelle (duplication). A: (1) de novo nucleation growth (2) templated assembly/growth (3) growth/fission
+- Ein <one>schnelles</one> <two>Protein</two> <three>benötigt für die Durchquerung des Zellkerns wie lange</three>? <one>Wenige Minuten</one>.
+- The <one>signal sequence of a protein</one> is related to folding in what way? It may <one>interfere</one> with the folding process.
+- <one>Welche Reaktion</one> führt die <two>Luciferase</two> genau durch? Nenne Input und Output. A: <one>Luciferin</one> + <one>ATP</one> + O2 ←→ <two>Oxyluciferin</two> + AMP + CO2.
+- <one>Proteins</one> <two>have different half-lives</two>. <three>What determines the half-life of a protein</three>? The <one>amino acids present at the N-terminus</one>.
+- Was wird im <one>smooth endoplasmic reticulum</one> <two>gebildet</two>? <one>Lipide</one> werden hier gebildet. URL: https://en.wikipedia.org/wiki/Endoplasmic_reticulum#Smooth_endoplasmic_reticulum
+- Eine <one>typische Eukaryotenzelle</one> <two>besitzt wieviele Proteasome</two> (also pro Zelle)? <one>30.000</one>.
+- Microscopy is very important in cell biology. We can see the <one>refractive index</one> here. <two>If we see a value such as 1.33, which is indicative of water, what does this mean</two>? That <one>light travels 1.33 times slower in water than it does in a vacuum</one>.
+- Name <one>the three most commonly used scaffolds</one> <two>for 3D cultures</two>. A: (1) <one>Agarose</one> (2) <one>Collagen</one> (3) <one>Fibronectin</one>
+- <one>Fibroblasts</one> <two>secrete what</two>? <one>Collagen</one>.
+- What is the major task of the <one>cis-Golgi network</one>? The <one>cis-Golgi network</one> receives the biosynthetic output from the ER.
+- How are the <one>specialized domains</one> <two>in cell membranes</two> called? <one>Lipid rafts</one>.
+- Der <one>Proteingehalt einer bakteriellen Zelle</one> <two>beträgt etwa n Prozent der Trockenmasse</two> (es reicht ein Wert, der innerhalb des Intervalls liegt)? Etwa <one>50-60% der Trockenmasse</one>.
+- What is <one>ferroptosis</one>? <one>Ferroptosis</one> is <two>a type of programmed cell death</two> <three>dependent on iron</three>.
+- What are <one>cathepsins</one> and <two>where are they activated</two>? <one>Cathepsins</one> are <two>proteases</two> which <three>become activated at the low pH found in Lysosomes</three>.
+- Within the cell, the <one>centromeres</one> <two>play a critical and very important role where exactly</two>? In the <one>segregation of chromosomes</one>.
+- Name the three Ras Proteins in humans. A: (1) H-Ras (2) K-Ras (3) <one>N-Ras</one>
+- <one>What functions</one> do the <two>Synaptotagmins</two> have? They <one>function as calcium sensors</one> in the regulation of neurotransmitter release and hormone secretion.
+- <one>Wo</one> <two>innerhalb einer Zelle</two> kann <three>Phosphoanhydrid</three> gefunden werden? In <one>ATP-Molekülen</one>.
+- <one>Cyclin-dependent kinases</one> <two>are a subclass of</two> <three>... which family</three>? They belong to the <one>serine</one>/<one>threonine protein kinases</one>.
+- Within a cell, <one>ArfGAP1</one> <two>contains motifs</two> <three>which specifically bind to ...</three>? <one>Small liposomes</one>.
+- Most <one>laminopathies</one> (== <two>diseases of the lamina</two>) <three>are associated with ...</three>, in a cellular context? A mutant version of lamin A.
+- <one>Phagosomes</one> have <two>diameters</two> that are determined by what exactly? The <one>diameters</one> <two>are determined</two> by the <three>size of the ingested particle</three>. In fact, <four>a phagosome can be almost as large as the phagocytic cell itself</four>!
+- Is <one>autophagy</one> useful only for <two>organelle turnover</two>? No - <one>it can also help protect an organism against intracellular threats</one>, such as <two>invading bacteria</two>.
+- <one>Which</one> <two>tubulin-subunits</two> are known? (1) <one>Alpha-Tubulin</one> (2) <one>Beta-Tubulins</one> (3) <one>Gamma-Tubulins</one>
+- Name <one>a protein</one> <two>that requires a large vesicle for its transport</two>. A: <one>Collagen</one>.
+- Nenne <one>drei Beispiele</one> für <two>Nucleoside</two>. A: (1) <one>Cytidin</one> (2) <one>Uridin</one> (3) <one>Guanosin</one>
+- <one>Nebulin</one> is <two>an actin-binding protein</two>. It is a very large protein. <three>Up to how many actin monomers can Nebulin bind</three>? It can bind bind up to as many as <one>200 actin monomers</one>.
+- <one>Wie lange</one> dauert die <two>S-Phase</two> in einer Säugetierzelle (von-bis)? <one>10-12 Stunden</one>.
+- <one>Welche Zellen</one> <two>reparieren Skelettmuskelfasern</two>? <one>Satellitenzellen</one>.
+- The protein <one>synaptotagmin</one> binds what? <one>Calcium</one> - in particular the <two>C2-domain</two>. URL: https://en.wikipedia.org/wiki/Synaptotagmin
+- <one>What exactly</one> is the backbone in <two>phosphoglycerides</two>? The 3-carbon <one>glycerol</one> is the backbone.
+- Warum der Name <one>F-Aktin</one> und <one>G-Aktin</one>? (1) <one>F-Aktin</one>:  <two>filamentöses Aktin</two> (2) <one>G-Aktin</one>:  <two>globuläres   Aktin</two>
+- Name <one>an ER-resident protein</one> that begins with the letter <two<P</two>. A: <one>Protein disulfide isomerase</one> (<two>PPI</two>).
+- <one>Woraus</one> besteht <two>ein einzelnes Tubulin-Molekül</two>? Es handelt sich hierbei um ein <one>Heterodimer</one>, bestehend aus <two>Alpha</two> und <two>Beta-Tubulin</two>.
+- In <one>multicellular, eukaryotic cells</one>: what is the most prominent cell cycle stage, e. .g the one that is used most often by eukaryotic cells? The <one>G0-phase</one>. URL: https://en.wikipedia.org/wiki/G0_phase
+- Nenne etwas bemerkenswertes bei <one>Mikrotubuli</one> und Genexpression? <one>Mikrotubuli</one> <two>bestehen aus zwei Untereinheiten</two>. Diese Untereinheiten werden gekoppelt exprimiert.
+- Name <one>three</one> <two>functional classification</two> of <three>cell junctions</three>. A: (1) <one>occluding junctions</one> (2) <one>anchoring junctions</one> (3) <one>communicating junctions</one>
+- In cellbiology: we have an abbreviation called <one>Cvt</one>. Why this weird name? <one>Cvt</one> means <two>Cytoplasm vacuole targeting</two>. It is sometimes called <three>Cytoplasm-to-vacuole targeting</three>, which may be confusing. URL: https://en.wikipedia.org/wiki/Cytoplasm-to-vacuole_targeting
+- <one>In which stage</one> <two>of the cell cycle</two> can we readily mark a cell with <three>radioactive thymidine</three>? In the <one>S phase</one>.
+- <one>5-Methylcytosin</one> ist methyliert, und <two>kann über eine Oxidation</two> in welche drei anderen Nukleotide konvertiert werden? (1) <one>5-Hydroxymethylcytosin</one> (<two>hmC</two>) (2) <one>5'-Formylcytosin</one>  (<two>fC</two>) (3) <one>5'-Carboxycytosin</one> (<two>caC</two>)
+- Wenn ein <one>Aktinfilament</one> <two>gecapped</two> wird, was bedeutet das für das Wachstum? Das Wachstum dieses Aktinfilaments kommt zum Erliegen.
+- Was heißt <one>GPI-anchor</one>? <one>Glycophosphatidylinositol anchor</one>. URL: https://en.wikipedia.org/wiki/Glycosylphosphatidylinositol
+- <one>What happens</one> when <two>the balance</two> between cell proliferation and elimination goes awry? <one>Cancer</one> <two>may form</two>, aka be initiated.
+- Die <one>Phospholipid-Synthese</one> <two>erfolgt wo in der Zelle</two>? An <one>der cytosolischen Seite der glatten ER-Membran</one>.
+- A <one>typical animal cell</one> is <two>n µm in diameter</two>. A: <one>10-20 µm in diameter</one>.
+- What does <one>the enzyme</one> <two>guanylate cyclase</two> <three>produce</three>? <one>cGMP</one>, which is <two>cyclic GMP</two>, synthesized from GTP. URL: https://de.wikipedia.org/wiki/Cyclisches_Guanosinmonophosphat
+- Name <one>one general way</one> to inhibit translation. A: <one>Make use of a microRNA</one>.
+- Nenne <one>drei</one> <two>allgemeine Funktionen der Mikrotubuli</two>. A: (1) <one>Formerhalt der Zelle</one> (2) <one>Geißeln</one> (3) Bewegung der Chromosomen bei der Mitose
+- <one>Wie</one> kann <two>bewiesen</two> werden, das sich Membranproteine lateral in der Membran bewegen können? Indem wir humane und Maus-Zellen fusionieren. Es kommt dadurch zum Durchmischen artspezifischer Proteine.
+- <one>Which three components</one> are required for <two>a human artificial chromosome</two>? (1) <one>centromere</one> (2) <one>telomeres</one> (3) <one>origin of replication</one>
+- Nenne <one>vier Phospholipide</one>, die <two>in einer Membran vorgefunden werden können</two>. A: (1) <one>Phosphatidylcholin</one> (PC) (2) Phosphatidylserin (PS) (3) Phosphatidylinositol (PI) (4) Phosphatidylethanolamin (PE)
+- <one>Warum</one> sieht das <two>rauhe Endoplasmatische Reticulum</two> so aus wie es aussieht? Da <one>mehrere Ribosomen</one> dort zu sehen sind.
+- In a <one>hepatocyte</one>: name <two>the two major constituents</two> belonging to an intracellular compartment, in regards to the <three>total cell volume</three>. A: (1) <one>Cytosol</one>     (<two>54%</two>) (2) <one>Mitochondria</one> (<two>22%</two>)
+- Die <one>Bax-Proteine</one> werden <two>durch welches Protein freigesetzt</two>? <one>p53</one>.
+- What is the function of the <one>ECM</one> (<one>extracellular matrix</one>)? The <one>ECM</one> <two>ties cells together</two>, enabling them to <three>form complex tissues</three>. URL: https://en.wikipedia.org/wiki/Extracellular_matrix
+- <one>Nanodiscs</one> <two>are surrounded by ...</two>? A <one>belt of proteins</one>.
+- Betreffend die <one>stoffliche Zusammensetzung einer Säugetierzelle</one> - <two>wieviel % Wasseranteil</two> hat eine solche Zelle, in etwa? <one>70%</one>.
+- <one>Wie</one> sind <two>die Mikrotubuli</two> in einer nicht-polarisierten Zelle verteilt? Die Plus-Enden befinden sich nahe an der Zellmembran, die Minus-Enden eher in der Mitte der Zelle.
+- What is a <one>chromocyte</one>? A <one>chromocyte</one> is <two>any cell that contains a pigment, especially red blood cells</two>. URL: https://en.wiktionary.org/wiki/chromocyte
+- The <one>focal adhesion kinase</one> (FAK) is <two>constitutively associated with</two> ... <three>which subunit of integrins</three>? With the <one>β-integrin</one>. URL: https://en.wikipedia.org/wiki/PTK2#Regulation
+- Define <one>transmembrane proteins</one>. A: These are <one>proteins</one> <two>that span the lipid bilayer</two>.
+- Was ist das <one>major cargo protein</one> im zellulären <two>Cvt Pathway</two>? <one>Aminopeptidase I</one> (<two>Ape1</two>).
+- <one>Inter-organellar connections</one> <two>depend on ...</two> which act as tethers to bridge the respective organelle membranes. A: <one>interacting proteins</one>.
+- What is <one>the general role of Gamma-Tubulin</one>? Gamma-Tubulin is involved in the nucleation of microtubule growth.
+- Nenne <one>drei verschiedene Plastid-Typen</one> <two>in alphabetischer Reihenfolge</two>. A: (1) <one>Chloroplasten</one> (2) <one>Chromoplasten</one> (3) <one>Leukoplasten</one>
+- In cell biology: <one>what happens</one> <two>if a late endosome combines with a lysosome</two>? An <one>autolysosome</one> is created.
+- <one>Wie</one> erfolgt <two>der Import</two> <three>von NLS-haltigen Proteinen</three>? Durch <one>Importin Alpha</one> und <one>Importin Beta</one>.
+- Was passiert mit <one>Glykoproteinen</one> die <two>phosphorylierte Mannosereste</two> aufweisen? Sie <one>werden</one> <two>in die Lysosomen</two> <one>transportiert</one>.
+- Durchmesser eukaryotischer Zellkerne (von-bis, in Mikrometer)? A: 5-20 Mikrometer.
+- <one>Microtubules</one> <two>are made of which protein</two>? <one>Tubulin</one>.
+- <one>Wieviele Billionen Zellen</one> besitzt <two>ein adulter Mensch</two> in etwa? <one>37.2 Billionen Zellen</one>.
+- The <one>GTP</one> bound to Beta-tubulin may be hydrolyzed to GDP shortly after assembly. What is the effect of this? <one>New dimers</one> are added to the Tubulin-Structure.
+- Sind <one>Centrioles</one> wichtig? <one>Ja</one> - <two>Centrioles</two> organisieren die <three>mitotic spindle</three>.
+- <one>Where</one> can <two>Plasmalogens</two> <three>be commonly found</three>? They can be found in cell membranes in the nervous systems.
+- <one>Integral membrane proteins</one> can be categorized as <two>type I</two> and <two>type II</two>. <three>What is the difference there</three>? (1) <one>Type I</one>:  these have their C-terminus towards the cytoplasm. (2) <one>Type II</one>: these have their N-terminus towards the cytosol.
+- Name <one>the two major roles</one> that <two>autophagy</two> has. A: (1) to remove damaged organelles and macromolecules (2) to recycle amino acids during periods of starvation
+- <one>Why</one> is <one>CO₂</one> <two>used for Live Imaging</two>? Because <one>this will yield a buffer</one> (CO2/HCO3⁻).
+- <one>Receptor-mediated endocytosis</one> <two>is initiated how</two>? When a specific ligand binds to receptors that are present on the cell surface.
+- <one>Nitric oxide</one> <two>can activate what inside of a cell</two>? The <one>guanylyl cyclase</one>.
+- What are <one>Neocentromeres</one> and <two>how do they originate</two>? <one>Neocentromeres</one> are <two>ectopic centromeres that originate occasionally from noncentromeric regions of chromosomes</two>.
+- <one>Wann</one> wurde <two>NLS</two> entdeckt und wo findet man sie? Die NLS-Sequenze wurde im Jahre <one>1982 entdeckt</one>; am C-Terminus befindlich. Sie kann jedoch auch an anderer Stelle der Peptidkette auftauchen.
+- What kind of information can we gain by <one>Endo H Cleavage</one>? <one>Endoglycosidase H</one> <two>can cleave certain oligosaccharide structures</two>. Later oligosaccharide structures are resistant to Endo H  cleavage, so the enzyme can be widely used to report the extent of oligosaccharide processing a protein of interest has undergone.
+- Why is <one>cholesterol</one> <two>preferentially localized to the upper region of a monolayer</two>? Because <one>the hydroxyl-group prefers an aqueous environment</one>.
+- The <one>main phospholipids</one> <two>in most animal cell membranes</two> are ... ? The <one>phosphoglycerides</one>.
+- The <one>Ras protein</one> <two>has a slow intrinsic ... activiy</two>. A: The <one>Ras protein</one> has a slow intrinsic <two>phosphatase-activity</two>, <three>converting GTP → GDP</three>.
+- <one>How</one> can a <two>lysosome</two> <three>maintain its acidic pH</three>? The lysosome contains a H⁺ pump in its membrane, which uses the energy from ATP hydrolysis to pump more H⁺ into the lysosome.
+- Nenne <one>zwei Genprodukte</one> die <two>für die Bildung des Autophagosoms wichtig sind</two>. A: (1) Atg1 Kinase Komplex (2) <one>PI3K</one>
+- The <one>fluid mosaic model</one> includes, obviously, the word <two>mosaic</two>. <three>What should this word indicate</three>? That this model <two>refers to the presence of proteins suspended in the membrane bilayer</two>.
+- For <one>animal cell culturing</one>, the substrate concentration of aminoacids is often very important, in particular <two>glutamine</two>. Why glutamine? Because <one>glutamine</one> <two>functions as an energy substrate</two>.
+- <one>Collagen fibrils</one> are <two>ropes with tunable ... </two>? <one>Stiffness</one>.
+- <one>What happens</one> if the <two>NLS</two> <three>is mutated</three>? This will lead to <one>cytosolic localization of the given package</one>.
+- Es gibt sogenannte <one>I-cell diseases</one>, <two>Inclusion-cell</two> diseases. Die sind Teil von <three>lysosomal storage disease families</three>. Welches Enzym ist hier defekt? Die <one>Phosphotransferase</one>, ein Enzym des Golgi-Apparatus.
+- Name a component of the <one>signal recognition particle (SRP)</one> complex. A: The <one>signal recognition particle RNA</one>, which is also known as the <two>7SL RNA</two>.
+- Nenne <one>zwei (allgemeine) Bedingungen</one> die eine Zelle erfüllen muss <two>um in die Mitose eintreten zu können</two>. A: (1) es dürfen <one>keine DNA-Schäden</one> vorhanden sein (2) die Zellen müssen eine <one>ausreichende Größe</one> erreicht haben
+- <one>With which assay</one> can we <two>determine</two> if a nuclear protein shuttles in or out of the nucleus? With help from a <one>Heterokaryon assay</one>.
+- Warum ist <one>Rapamycin</one> (<two>RAPA</two>) in der Zellbiologie wichtig? Weil <one>Rapamycin</one> als <two>Immunosuppressivum</two> wirken kann, und auch die Entwicklung von Krebs behindert.
+- <one>Was passiert</one> bei <two>Zugabe von ATP</two> zu <three>Actinmonomeren</three>? Es erfolgt eine <one>Konformationsänderung in Actin</one>; dieses assoziiert mit 2 anderen Actin-Monomeren. Dies kann der <two>Beginn für die Entstehung eines Actin-Filaments</two> sein.
+- Das <one>Glykoproteinhormon EPO</one> <two>hat n AA</two>? <one>165</one>.
+- <one>Phospholipide</one> <two>können in der Membran bewegt werden</two>. Nenne die vier grundlegenden <two>Bewegungsarten</two>. A: (1) laterale diffusion (2) <one>Flexion</one> (3) <one>Rotation</one> (4) <one>transversale Diffusion</one>
+- Nenne einen <one>Unterschied</one> zwischen <two>Mitosis</two> und <two>Meiosis</two>. A: Die Produkte der Meiosis sind haploid.
+- <one>How</one> can we <two>visualize</two> <three>lipid rafts</three> <four>in membranes</four>? Via the <one>AFM</one> (<two>atomic force microscope</two>).
+- Zellulär betrachtet: was heißt <one>Atg8</one> und warum ist <one>Atg8</one> wichtig? <one>Atg8</one> heißt <two>Autophagy-related protein 8</two>. Es ist ein ubiquitin-like Protein, das für die Bildung von autophagosomalen Membranen wichtig ist. Die Konjugation von Atg8 an die autophagosomale Membran ist für die Autophagie in Eukaryoten essenziell.
+- Name <one>a big advantage</one> that <two>multicellularity</two> brought. A: <one>Bigger organisms</one> are able to access more nutrients than do unicellular organisms.
+- <one>To which family</one> do the <two>death receptors</two> belong to? <one>TNF receptor family</one>.
+- Zellbiologisch heraus betrachtet: wieso hat <one>Koffein</one> eine <two>stimulierende Wirkung</two>? Es <one>hemmt die Phosphodiesterase</one>, und <two>bedingt dadurch einen langsameren Abbau von cAMP</two>.
+- <one>Wo</one> vor allem könnten wir das Protein <two>Dynein</two> finden? In <one>Flagellen</one> oder <one>Spermatozoa</one>.
+- <one>Wann</one> setzt die Zelle das Enzym <two>Glutamine Synthetase</two> ein? Wenn die <one>NH₃-Konzentration niedrig ist</one>.
+- In <one>cell biology</one>: <two>give another expression</two> <three>for</three> <four>reversable cell cycle arrest</four>. A: <one>Quiescence</one>.
+- Das <one>Porin</one>-Protein <two>in Mitochondrien</two> <three>erlaubt einen Durchtritt von Molekülen bis zu n Dalton durch</three>? <one>600 Dalton</one>.
+- What is <one>the best source for microtubules</one>? <one>Brains</one>.
+- <one>Ionenkanäle</one> <two>können kontrolliert werden</two>. <three>Nenne hierzu drei Möglichkeiten</three>. A: (1) <one>spannungskontrolliert</one> (2) <one>ligandenkontrolliert</one> (Transmitter, Ionen, Nukleotide) (3) <one>mechanisch kontrolliert</one>
+- Wie schaffen es <one>Lysosomen</one> <two>einen niedrigeren pH-Wert als ihre Umgebung zu halten</two>? Sie besitzen eine <one>Protonenpumpe der Klasse V</one>, die unter ATP-Verbrauch Protonen in den Lysosomen anreichert.
+- Name <one>one important receptor</one> <two>that is degraded within lysosomes</two>. A: <one>EGFR Receptor</one> (this is a safety mechanism).
+- Why the <one>Z</one> in <two>FtsZ</two>? Because <one>it will build the Z ring</one> <two>at the site where the septum forms</two>.
+- <one>Who</one> <two>invented the wheel</two>? Actually <one>prokaryotes</one>, via their <two>ATPase</two>.
+- The <one>Glucose-Transporter</one> (<one>GLUT</one>) is <two>an example for what kind of transporter</two>? <one>GLUT</one> is a <two>uniporter transporter protein</two>. URL: https://en.wikipedia.org/wiki/Glucose_transporter
+- <one>Where</one> can <two>RanGAP</two> and <two>RanGEF</two> <three>be found</three>, respectively? (1) <one>RanGAP</one>: only in the <two>cytoplasm</two> (2) <one>RanGEF</one>: only in the <two>nucleus</two>
+- <one>Which enzyme</one> <two>catalyzes the synthesis of cGMP</two>? <one>Guanylate cyclase</one>.
+- <one>Which</one> <two>categories of SNAREs</two> exist? (1) <one>vesicle</one> or <one>v-SNAREs</one>: <two>these are incorporated into the membranes of transport vesicles during budding</two> (2) <one>target</one> or <one>t-SNAREs</one>:  <two>these are located in the membranes of target compartments</two>
+- Die <one>Form von Mitochondrien</one> ist unter anderem wovon abhängig? Vom <one>metabolischen Zustand</one>.
+- Nenne <one>ein Beispiel</one> für <two>einen Regulator der ras-Aktivität</two>. A: <one>NF1</one>.
+- Name <one>four different families</one> of <two>cellular adhesion proteins</two>. A: (1) Ig-CAMs (2) cadherins (3) integrins (4) <one>selectins</one>
+- In <one>prokaryotic cells</one> (such as <two>E. coli</two>), what is the most abundant membrane Phospholipid? <one>Phosphatidylethanolamine</one>.
+- <one>Warum</one> besitzen <two>Archaea</two> <three>Etherbindungen</three>? Da <one>Esterbindungen</one>, wie in Bacteria und Eukaryoten, <two>unter extremen Bedingungen rasch hydrolysieren würden</two>.
+- For <one>clathrin-coated buds</one>: <two>which protein</two> assembles at the neck of the bud? <one>Dynamin</one>.
+- Within a <one>monolayer</one>, <two>where</two> can we find <three>cholesterol</three>? <one>Cholesterol</one> is preferentially localized to the upper region of the monolayer because the hydroxyl-group prefers an aqueous environment.
+- <one>Why</one> is it important that the <two>ER</two> (<two>endoplasmic reticulum</two>) has a large surface area? This helps in <one>biochemical synthesis</one>.
+- Was meinen wir mit einer <one>asymmetrischen Zellteilung</one>? Dies ist schlicht <one>eine Zellteilung, bei der die beiden Tochterzellen unterschiedlich groß sind</one>.
+- <one>Mice without p53</one> <two>show what phenomen</two>, in general? They are <one>susceptible to early tumours</one>.
+- In der Zellbiologie binden die <one>MAPs</one> (<two>Microtubule-associated protein</two>) an Tubulin Subunits. <three>Welche Funktion erfüllt dies</three>? Sie <one>regulieren damit deren Stabilität</one> - machen sie also stabiler oder instabiler.
+- <one>Nucleoporins</one> <two>contain</two> in particular <three>which two-aminoacid repeats</three>? <one>FG</one>, aka <two>Phe</two>/<two>Gly repeats</two>.
+- What is a <one>Ionophore</one>? This is <one>a lipid-soluble molecule</one> usually synthesized by microorganisms, able to transport ions across the lipid bilayer of the cell membrane.
+- <one>Where</one> are <two>cell membranes</two> <three>synthesized</three>? Membranes and their constituent proteins are assembled <one>in the ER</one>.
+- Give <one>two examples</one> <two>for materials</two> cells like to adhere to. A: (1) <one>polylysine</one> (2) <one>extracellular matrix components</one>
+- The <one>human body</one> contains about n cells? <one>10¹⁴ cells</one>.
+- Zellulär betrachtet: <one>wo</one> kann das Protein <two>Cathepsin D</two> gefunden werden? In <one>Lysosomen</one>.
+- <one>What happens</one> to <two>p53</two> <three>upon activation</three>? It will be <one>translocated into the nucleus</one>.
+- <one>Human CDKs</one> contain <two>a modified ATP-binding site</two> <three>that can be regulated by ... </three>? It can be regulated by <one>cyclin binding</one>.
+- <one>Wieviele Ribosomen</one> könnte man in eine <two>Mycoplasma-Zelle</two> (im Durchmesser) <three>packen</three>? <one>10</one>.
+- Name the <one>three major coat proteins</one> <two>in a cell</two>. A: (1) clathrin-coated (2) <one>COPI-coated</one> (3) <one>COPII-coated</one>
+- <one>Kompartimente</one> erfordern ...? <one>Proteinsortierung</one>.
+- <one>Chaperone-mediated autophagy</one> (<two>CMA</two>) <three>involves the recognition by ... which complex</three>? The <one>hsc70-containing complex</one>.
+- <one>Cargo</one> within the cell can be <two>sent via vesicles</two>, which must be cleave off during the <three>scission</three> step. <four>Which enzymes catalyze this reaction usually</four>? <one>GTPases</one>, such as <two>dynamin</two>.
+- <one>Microtubules</one> <two>are organized from ...</two>? <one>Centrosomes</one>.
+- <one>How comes</one> <two>a cell manages to counteract</two> <three>incorrect stop codons</three>? This is achieved by a process called <one>NMD</one> (<two>nonsense mediated decay</two>).
+- Lassen <one>tight junctions</one> <two>Nährstoffe</two> <three>durch</three>? <one>Nein</one>.
+- Nenne die <one>drei Hauptgruppen von Membranlipiden</one>. A: (1) Glykolipide (2) <one>Phospholipide</one> (3) <one>Cholesterin</one>
+- Name <one>one important but unusual environmental cue for a cell in a multicellular organism</one>. A: <one>Signals</one> <two>from the other cells</two>.
+- <one>Incoming transport vesicles</one> <two>move to the Golgi apparatus</two>. <three>Where to first</three>? Towards the <one>cis-face</one> of the Golgi apparatus.
+- <one>Multicellularity</one> is in general a successful strategy, but <two>there is at the least one major drawback when compared to unicellularity</two>. Which one is that? It takes longer before <one>reproduction</one> can occur.
+- <one>Warum</one> sind <one>Vesikel</one> für die Zelle so wichtig? Weil die Zelle damit <one>Moleküle zwischen Organellen und dem Aussenmilieu verschicken kann</one>.
+- In der Zellbiologie gibt es ein sehr wichtiges, dimeres (genauer: heterodimeres) Protein namens <one>MPF</one>. Wofür steht die Abkürzung <one>MPF</one>? <one>Maturation-promoting factor</one>. Manchmal wird es aber auch <two>mitosis-promoting factor</two> bezeichnet.
+- Gehören die <one>Lysosomen</one> zum <two>Endomembransystem</two>? <one>Ja</one>.
+- The <one>Gamma-Tubulin Ring complex</one> <two>is built where exactly</two>? At the <one>minus end of Microtubules</one>.
+- Name the <one>three Ras Proteins in Humans</one>. A: (1) <one>H</one>-<two>Ras</two> (2) <one>K</one>-<two>Ras</two> (3) <one>N</one>-<two>Ras</two>
+- The <one>Rab GTPase</one> <two>is important for ... </two>? <one>Organelle identity</one>.
+- <one>Welche zelluläre Funktion</one> haben <two>Intermediärfilamente</two>? <three>Nenne zudem Beispiele für Intermediärfilamente</three>. A: <one>Intermediärfilamente</one> dienen der <two>Erhöhung der mechanischen Stabilität der Zelle</two>. Sie haben einen Durchmesser von 10 nm und liegen somit zwischen Aktinfilamenten (7 nm) und Mikrotubuli (25 nm). Intermediärfilamente bilden mit Mikrotubuli und Aktinfilamenten das Cytoskelett der Zelle. "Desmine" und "Lamine" sind Beispiele für Intermediärfilamente.
+- Give another name for the <one>centrosome</one>. A: <one>MTOC</one>: <two>Microtubule organizing center</two>. URL: https://en.wikipedia.org/wiki/Microtubule_organizing_center
+- Nenne <one>sechs Organellen</one>. A: (1) der <one>Zellkern</one> (2) die <one>Mitochondrien</one> (3) die <one>Chloroplast</one> (4) die <one>Lysosome</one> (5) die <one>Peroxisome</one> (6) das <one>endoplasmatische Retikulum</one> (7) der <one>Golgi-Apparat</one> (bei manchen Definitionen)
+- Which <one>energy form</one> does the cell use for <two>actin</two> and <two>tubulin</two> subunits? (1) <one>Actin</one>:   <two>ATP</two> (2) <one>Tubulin</one>: <two>GTP</two>
+- Does <one>FRAP</one> (<two>fluorescence recovery after photobleaching</two>) <three>make use of GFP proteins</three>? <one>Yes</one>. URL: https://en.wikipedia.org/wiki/Fluorescence_recovery_after_photobleaching
+- What happens when <one>lipids</one> go beyond a certain temperature? Also name a consequence of this. A: They turn into a <one>paracristalline form</one> - hence, <two>they can no longer rotate freely</two>.
+- Nenne <one>zwei Aufgaben der Peroxisomen</one>. A: (1) <one>Oxidativer Abbau von Fettsäuren</one> (2) <one>Entgiftung von toxischen Substanzen</one>
+- <one>COP-Proteine</one> <two>in Vesikeln</two> <three>dienen dem Transport zwischen ...</three>? <one>ER</one> und <one>Golgi</one>.
+- The <one>Sec23 gene</one> is <two>part of a protein complex in a cell</two>. Where can it be found inside of a cell? In the <one>endoplasmic reticulum</one>.
+- Die <one>Fluidität der Plasmamembran</one> <two>ist geringer als</two> <three>die in der intrazellulären Membran auf Grund des hohen Gehalts an ... </three>? <one>Cholesterin</one>.
+- In der Zellbiologie: wofür steht die Abkürzung <one>NA Wert</one>? <one>Numerical Aperture</one>. URL: https://en.wikipedia.org/wiki/Numerical_aperture
+- In der Zellbiologie: der Begriff <one>Autophagy</one> wurde von <two>Christian de Duve</two> geprägt. <three>In welchem Jahr</three>? <one>1963</one>.
+- <one>Eine menschliche Pankreaszelle</one> besitzt wieviele Ribosomen? Einige Millionen.
+- <one>How many different cell types</one> can we find in the human body? <one>210</one>.
+- Es gibt nicht nur <one>GFP</one> sondern auch <two>CFP</two> sowie <two>YFP</two>. <three>Wofür stehen diese Abkürzungen jeweils</three>? (1) <one>CFP</one> ist <two>cyan fluorescent protein</two>. (2) <one>YFP</one> ist <two>yellow fluorescent protein</two>.
+- Was heisst <one>mTOR</one> in der Zellbiologie? <one>Mammalian target of rapamycin</one> - beziehungsweise heutzutage <two>mechanistic target of rapamycin</two>. URL: https://de.wikipedia.org/wiki/MTOR
+- Eine typische <one>Eukaryotenzelle</one> <two>hat etwa n Nuclear Pore Complexes</two> (<three>NPC</three>), von-bis? Etwa <one>3000-5000 dieser NPCs</one>.
+- <one>Periphere Mikrotubuli</one> <two>in den Geisseln</two> sind miteinander wie verbunden? Durch das Motorprotein <one>Dynein</one>.
+- <one>Sphingosine</one> plays a role in cell membranes. It is a is a long acyl chain with ... and two hydroxyl groups (OH) at one end. <two>What is the other part</two>? An <one>amino group</one> (<one>NH₂</one>).
+- Erlauben <one>Transfersequenzen</one> den <two>gerichteten (= Polarität) Einbau von Proteinen in Membranen</two>? <one>Ja</one>.
+- Nenne <one>ein Beispiel</one> für <two>ein kleines Signalmolekül, das eine zelluläre Rolle spielt</two>. A: <one>NO</one> (<two>Stickstoffmonoxid</two>).
+- <one>Vorgänger</one> eines <two>Lysosomes</two>? Ein <one>late endosome</one>.
+- From the point of view of cellbiology: <one>how</one> can the <two>DNA in a cell be called</two>, in regards to the cell as the focus of the question? <one>DNA</one> is the <two>genomic repository of a cell</two>.
+- Within a given cell, the so-called <one>FG repeats</one> <two>are associated with ... </two>? <one>Karyopherins</one>.
+- Is it possible to detect a small object below the resolution limit, in light microscopy? <one>Yes</one>, <two>if said object itself emits light</two>.
+- <one>Wie</one> gelangt <two>Pyruvat</two> in das Mitochondrium? Über einen <one>H⁺</one>-<two>Symporter</two>.
+- Do <one>plant cells</one> <two>make use of the KDEL sequence</two>? <one>Yes</one>.
+- What is <one>the net effect</one> of <two>mitosis without cytokinesis</two>? <one>Cells with multiple nuclei</one> will be the result.
+- Give one example for <one>actin based motor proteins</one>. A: <one>Myosins</one>. URL: https://en.wikipedia.org/wiki/Myosin
+- What is the job of the <one>PIN Proteins</one> in plants? PIN proteins serve as <one>secondary active transporters</one> in the cell membrane, regulating the influx and efflux of auxins.
+- <one>How</one> does a cell cope with a <two>residual body</two>? (1) it <one>can release the content of residual body by exocytosis</one> (2) it can be retained within the cytoplasm, and become a "lipofuscin granule".
+- <one>Rab6 proteins</one> <two>fulfil which cellular role</two>? They direct a vesicle to specific spots on the correct target membrane.
+- How do we call <one>the two layers of the phospholipid-bilayer</one>? <one>Leaflets</one>. URL: https://en.wikibooks.org/wiki/Structural_Biochemistry/Lipids/Lipid_Bilayer
+- <one>Vinculin</one> <two>kann welch anderes Protein binden</two>? <one>Actin</one>.
+- <one>The process</one> <two>by which an aged organelle is degraded</two> <three>in a lysosome</three> <four>is called ... </four>? <one>Autophagy</one>.
+- Was heißt bei den <one>Tor-Kinasen</one> die Abkürzung <two>Tor</two>? <one>Target of Rapamycin</one>.
+- Most <one>animal cells</one> have a <two>covering</two> over the plasma membrane. <three>How is this covering called</three>? <one>Glycocalyx</one>. URL: https://de.wikipedia.org/wiki/Glykokalyx
+- <one>Welche Mikrotubuli</one> reichen <two>von Zellpol zu Zellpol</two>? Die <one>Polar-Mikrotubuli</one>.
+- What is the <one>D</one> and <one>T</one> form of actin filaments? (1) the <one>D form</one> ... <two>with bound ADP</two> (2) the <one>T form</one> ... <two>with bound ATP</two>
+- <one>Which hormone</one> causes <two>apoptotic loss of the tail in frogs</two>? The <one>thyroid hormone</one>.
+- Name <one>the four main families of motor proteins</one> in human cells. A: (1) Integrins (2) Immunoglobulins (3) Cadherins (4) Selectins
+- <one>Which stain</one> was <two>originally used to identify the Golgi-apparatus</two>? A <one>silver stain</one>. URL: https://en.wikipedia.org/wiki/Golgi%27s_method
+- <one>Wann</one> gibt <two>Aequorin</two> <three>Licht ab</three>? Bei Zugabe von (geringen Mengen) <one>Ca²+</one>.
+- What is the <one>intracellular signal</one> that <two>triggers macroautophagy</two>? The <one>intracellular levels of particular amino acids</one>.
+- Nenne <one>eine Substanz, die Mikrotubuli stabilisieren kann</one>. A: <one>Taxol</one>. URL: https://de.wikipedia.org/wiki/Paclitaxel
+- Are <one>phospholipid membranes</one> <two>permeable to water</two>? <one>No</one>, they are <two>impermeable to water</two>.
+- In der Zellbiologie: was ist <one>Vimentin</one>? <one>Vimentin</one> ist <two>ein Typ 3 Intermediärfilament</two> das eine wichtige Rolle bei der Verankerung von Organellen im Cytosol spielt.
+- Name <one>three detergents</one> used in cellbiology. A: (1) <one>SDS</one> (2) <one>Triton X-100</one> (3) <one>Beta-octylglucoside</one>
+- Give another word/term for the <one>centrosome</one>. A: <one>Microtubule organizing center</one>. URL: https://en.wikipedia.org/wiki/Microtubule_organizing_center
+- <one>Who</one> <two>can reverse ubiquitination events</two>? The <one>Deubiquitinases</one>. URL: https://en.wikipedia.org/wiki/Deubiquitinating_enzyme
+- <one>Actin Filamente</one> haben einen <two>nucleation point</two>, der von einem Komplex ausgeht, welcher wiederum 7 Proteine hat. Wie heisst dieser Komplex, und wofür steht die Abkürzung? <one>Arp2</one>/<one>3 complex</one>. <two>Arp</two> steht für <three>Actin-Related Protein</three> - ARP ähnelt Aktin strukturell.
+- <one>Zellmembranen</one> wirken als ...? <one>Osmotische Schranken</one>.
+- <one>Cytokines</one> <two>can convey to the cells signals to induce ...</two> which four different cell-specific phenomena, all starting with the word <three>cell</three>)? (1) <one>cell proliferation</one> (2) <one>cell specialization</one> (3) <one>cell interaction</one> (4) <one>cell movement</one>
+- <one>What would happen</one> if we would <two>knock out</two> <three>lysosomal hydrolases</three>? <one>Undigested molecules would accumulate in lysososomes</one>, causing the cell to swell and ultimately die.
+- In cell biology: what does the term <one>photobleaching</one> mean? <one>Photobleaching</one> is <two>the photochemical destruction of a fluorophore</two>.
+- <one>Welche Aufgabe</one> hat die <two>Alpha-Subunit</two> bei G-Proteinen? Diese Untereinheit ist eine <one>GTPase</one>. Die Alpha-Untereinheit bei G-Proteinen hydrolysiert GTP zu GDP; dies inaktiviert das G-Protein.
+- Do <one>gap junctions</one> <two>allow passage</two>? <one>Yes</one>; of <two>small water-soluble molecules</two>.
+- What means <one>dynamic instability</one> in <two>microtubules</two>? That <one>microtubules</one> <two>undergo phases of growth and shrinkage</two>.
+- In der Zelle: <one>wie</one> wird <two>dGTP</two> hergestellt? Ausgehend von der <one>GDP-Ribose</one>, über die Ribonucleotide Reduktase, hin zu dGDP, danach fügt eine Kinase ein P hinzu und es entsteht dGTP.
+- In der Zellbiologie: <one>welche Rolle</one> spielen <two>multivesicular bodies</two>? Sie spielen eine Rolle beim Transport von ubiquitinierten Proteinen und Rezeptoren in ein Lysososome.
+- Das <one>ced-4 Genprodukt</one> <two>aktiviert welches andere Protein</two>? Die <one>ced-3 Caspase</one>.
+- <one>Inositol</one> besitzt <two>n OH-Gruppen</two>? <one>6</one>. URL: https://en.wikipedia.org/wiki/Inositol
+- In cellbiology: <one>Shibire</one> is a <two>temperature sensitive phenotype</two> in Drosophila. <three>What happens at high temperature, and why</three>? The <one>flies become paralysed at high temperature</one>. The phenotype is the result of the inability of endocytic vesicles to be separated from the parent membranes and thus there is a depletion of vesicles especially in synaptic terminals.
+- Bei der <one>Dynamik von Mikrotubuli</one>/Tubulin" in der Zelle hat <two>Alpha-Tubulin</two> eigentlich immer "GTP" gebunden. Lediglich Beta-Tubulin unterscheidet sich in seinem Verhalten, je nachdem ob es GTP oder GDP gebunden hat. Wie unterscheidet sich Beta-Tubulin bei "GDP" und "GTP" dahingehend jeweils? (1) Beta-Tubulin mit "GDP": "Zerfall der Mikrotubuli" (2) Beta-Tubulin mit "GTP": <two>Polymerisierung der Mikrotubuli</two>
+- Der <one>ABC-Transporter</one> ist membrangebunden und <two>kann ATP binden</two>. <three>Auf welcher Seite der Zellmembran bindet dieser Transporter ATP</three>? Auf der <one>cytosolischen Seite</one>.
+- Name <one>two categories</one> of <two>endocytosis</two>. A: (1) <one>bulk-phase endocytosis</one> (2) receptor-mediated endocytosis
+- What does a <one>mast cell</one> secrete? <one>Histamine</one>. URL: https://en.wikipedia.org/wiki/Mast_cell
+- A <one>32 base pair deletion</one> can confer <two>HIV resistance</two>. In which human gene? <one>CCR5</one>.
+- Give another, more interesting expression for the <one>addition of a ubiquitin tail</one>. A: The <one>kiss-of-death</one>.
+- <one>Cell lines</one> are <two>usually derived from</two> ... ? <one>Tumors</one>.
+- Der <one>retrograde transport</one> bei <two>COP I</two> verläuft von ... zu ...?  <one>Von Golgi</one>, <two>zum ER</two>.
+- <one>Who</one> produces <two>lysosomes</two>? The <one>Golgi complex</one>. URL: https://en.wikipedia.org/wiki/Golgi_apparatus
+- <one>The basis for asexual reproduction</one> <two>is given by ... </two>? <one>Mitosis</one>. URL: https://en.wikipedia.org/wiki/Mitosis
+- Nenne <one>drei konkrete Funktionen des glatten ERs</one>. A: (1) <one>Synthese von Lipiden</one> (2) Kohlenhydratstoffwechsel (3) Detoxifizierung von Giften
+- Is <one>a human egg</one> or <one>a human red blood cell</one> larger? A <one>human egg is larger</one> than a red blood cell.
+- Is it easy <one>to stretch a membrane</one>? <one>No</one>.
+- Nenne <one>die fünf Phasen</one> der <two>Meiose I</two> in korrekter Reihenfolge. A: (1) <one>Leptotän</one> (2) <one>Zygotän</one> (3) <one>Pachytän</one> (4) <one>Diplotän</one> (5) <one>Diakinese</one>
+- <one>How</one> can we detect <two>apoptotic cells</two>? Via <one>TUNEL Labeling</one>.
+- Diameter of the <one>megakaryocytes</one> (up to)? Up to <one>60 micrometer</one>.
+- Was ist <one>das gemeinsame Merkmal aller G-Proteine</one>? Eine <one>hoch konservierte G-Domäne</one>.
+- Das <one>KDEL Signal</one> lässt sich <two>wo finden</two>? Am <one>C-terminalen Ende</one> <two>einer Polypeptidkette</two>.
+- Nenne <one>vier Motorproteinklassen</one> in alphabetischer Reihenfolge. A: (<one>D</one>, <one>K</one>, <one>M</one>, <one>P</one>) (1) <two>Dynein</two> (2) <two>Kinesin</two> (3) <two>Myosin</two> (4) <two>Prestin</two>
+- <one>Ribosomes</one> are one of the most abundant macromolecules in the cell. Compare the amount of ribosomes <two>per yeast cell</two> and <two>per HeLa cell</two>, in numbers. A: (1) <one>yeast cell</one>: about   <two>200.000 ribosomes</two> (2) <one>HeLa cell</one>:  about <two>3.000.000 ribosomes</two> [Warner, 1999]
+- <one>Humans</one> <two>have n actin genes in their genome</two>? <one>6</one>.
+- In der Zellbiologie: was heißt <one>ESCRT</one>? The <one>endosomal sorting complex required for Transport</one>. URL: https://en.wikipedia.org/wiki/ESCRT
+- <one>Welche Gene</one> <two>verzögern den Zellzyklus</two>? <one>Tumorsuppressor-Gene</one>.
+- <one>Acetyl-Coenyzm A</one> <two>besteht aus</two>? <one>Pyruvat</one> und Coenzym A.
+- Andere Bezeichnung für <one>lösen</one>, in bezug auf die Zellbiologie? <one>Solubilisieren</one>.
+- In general: <one>which two types of cilia exist</one>? (1) <one>motile cilia</one> (2) <one>nonmotile cilia</one>, also called <two>primary cilia</two>
+- Name <one>three skeletal proteins</one>, starting with the letters A,V,F. A: (1) Actin (2) Vinculin (3) <one>Fibronectin</one>
+- Name <one>a bacterial homolog of actin</one>. A: <one>MreB</one>.
+- Der <one>Zellzyklus</one> umfasst <two>7 prominente Punkte</two> (die <i>checkpoints</i> ausgenommen). <three>Welche sind dies</three>? A: <one>(G0)G1,R,S,G2,M,Cytokinese</one>.
+- Nenne eine <one>Pumpe</one> in den Membranen der Lysosomen. A: <one>H⁺ ATPase</one>.
+- Nenne <one>die drei Domänen</one> des <two>Glykophorin</two>. A: (1) <one>extrazelluläre Domäne</one> (2) <one>Transmembrandomäne</one> (3) <one>cytoplasmatische Domäne</one>
+- Der <one>MPF</one> (<one>Mitosis-promoting factor</one>) <two>wird wann und wie aktiviert</two>? <one>MPF</one> wird am Ende der G2-Phase durch eine Phosphatase aktiviert, die eine hemmende (inhibitory) Phosphat-Gruppe entfernt.
+- <one>Chaperones</one> not only help during protein folding, but <two>may also reduce which unwanted side effect</two>? <one>Aggregation</one>, that is, the <two>accumulation of unfolded proteins</two>.
+- <one>Who</one> proposed the structure for the <two>nucleosome</two>? <one>Roger Kornberg</one>.
+- In cellbiology: what is a <one>CKI</one>? This is a <one>cyclin-dependent kinase inhibitor</one>.
+- What is meant with the term <one>translational frameshifting</one>? When the cell ignores a stop codon.
+- The <one>interaction of light with an object</one> changes the phase relationships of the light waves in a way that produces complex ... effects. A: <one>Complex interference effects</one>.
+- Within a cell: <one>what happens</one> if a protein loses its KDEL Sequence? This protein can no longer be retained within the ER.
+- Define the term <one>heterotrophy</one>. A: At least two genetically different types of mitochondria (or other organelles) are present in the same cell.
+- <one>Why</one> is <two>Cholesterol</two> preferentially localized to the upper region of the lipid monolayer? Because <one>its hydroxyl-group prefers an aqueous environment</one>.
+- Why is the <one>26S-proteasome</one> important for a cell? (1) The <one>26S-proteasome</one> can <two>eliminate defective proteins</two>. (2) The <one>26S-proteasome</one> can <two>regulate cellular processes</two>.
+- What are <one>early endosomes</one>? Bubbles that exist directly after being pinched off. They are mildly acidic, so not much degradation has yet taken place. As the early endosome migrates deeper into the cell, it becomes more and more acidic and evolves into a late endosome.
+- Has <one>autophagy</one> <two>an important additional role aside from organelle turnover</two>? <one>Yes</one> - <two>autophagy</two> <one>is also an immune mechanism</one>. It plays a role in the destruction of <two>intracellular pathogens</two>.
+- The <one>smooth endoplasmic reticulum</one> is called <two>smooth</two> because ... ? Because it <one>lacks ribosomes</one>. URL: https://en.wikipedia.org/wiki/Endoplasmic_reticulum#Smooth_endoplasmic_reticulum
+- Der <one>cis-golgi</one> ist <two>wem</two> zugewandt? Dem <one>ER</one>.
+- <one>ARF-GAP1</one> ist was für ein Proteintyp? Ein <one>GAP</one>: <two>GTPase-activating protein</two>.
+- There is <one>a hormone</one> which <two>transforms</two> a tadpole into a frog. <three>Which hormone is that</three>? <one>Thyroid hormone</one>. URL: https://en.wikipedia.org/wiki/Thyroid_hormones
+- In <one>Live Imaging</one> there is a <two>triangle of frustration</two>. What are the three major points? (1) <one>sensitivity</one>  aka <two>see something</two> (2) <one>speed</one>     aka <two>temporal resolution</two> (3) <one>nice picture</one> aka <two>spatial resolution</two>
+- <one>Which three general functions</one> may a <two>P body</two> have? (1) "storeage" (2) <one>repression</one> (3) <one>degradation</one>
+- In cell biology, we know the <one>ARP complex</one>. <two>What other name is given to this complex</two>? The Arp 2/3 complex.
+- Name <one>two</one> <two>degradation organelles</two>. A: (1) the <one>26S-Proteasome</one> (2) the <one>lysosomes</one>
+- What means <one>cellular respiration</one>? This is how cells consume O₂ and produce CO₂.
+- <one>Wo</one> kann das Protein <two>Spectrin</two> gefunden werden? <one>Spectrin</one> ist ein <two>Cytoskelett-Protein</two>, das wir <three>in Erythrozyten</three> finden können. Es bildet unterhalb der Erythrozytenmembran ein Proteinnetzwerk.
+- In cellbiology: <one>what is the primary role of SNARE proteins</one>? <one>SNARE proteins</one> <two>mediate vesicle fusion</two>, that is, the exocytosis of cellular transport vesicles with the cell membrane at the porosome or with a target compartment, such as a lysosome.
+- <one>Which cell type</one> <two>expresses P-selectin constitutively</two>? The <one>endothelial cells</one>.
+- <one>How</one> does a <two>mRNA</two> with premature stop codons arise in humans, most likely? Due to <one>improper splicing</one>.
+- <one>Warum</one> führt die Zelle <two>Farnesylierungen</two> durch? Um Proteine fest mit der Membran zu assoziieren.
+- In nm: what is the <one>diameter</one> of a typical <two>Nuclear Pore Complex</two>? <one>125 nm diameter</one>.
+- What is the <one>cis-Golgi</one>? The cis-Golgi is the Golgi stack <one>closest to the ER</one>.
+- The <one>SRP</one> (<two>signal recognition particle</two>) can bind to ...? (1) The <one>ribosome</one> (2) the <one>signal sequence</one>
+- Give <one>three examples</one> for <two>G-protein-coupled receptors</two>. A: (1) muscarinic receptor (2) adrenergic receptor (3) <one>opioid receptor</one>
+- We can convert <one>heme</one> into which <two>photoreceptor pigment</two>? Into <one>phycocyanobilin</one>.
+- The <one>limiting separation</one> at which two objects appear distinct is called <two>the limit of resolution</two>. It depends, primarily, on which two features? (1) the <one>wavelength of the light</one> (2) the <one>numerical aperture of the lens system used</one>
+- In <one>cell biology</one>: what does the term <two>transfection</two> mean? The process of deliberately introducing nucleic acids into cells.
+- Was fungiert als <one>allgemeine, zelluläre Zeitschaltuhr</one> in einer Zelle? Die <one>G-Alpha Untereinheit mit gebundenem GTP</one>, in den trimeren G-Proteinen.
+- <one>Chromatin</one> besteht grob formuliert, in Prozent, aus? <one>45% Protein</one>, <two>55% DNA</two>.
+- <one>Cells</one> can degrade proteins without lysosomes - give a proof for this statement. A: <one>Reticulocytes</one> lack lysosomes but can still selectively degrade abnormal proteins.
+- Wir können zwischen <one>primären Lysosomen</one> und <one>sekundären Lysosomen</one> unterscheiden. <two>Was ist das wichtigste Unterscheidungskriterium hierzu</two>? Die primären Lysosomen werden vom Golgi Apparat abgeschnürt. Sie enthalten neu gebildete, noch nicht aktive lysosomale Enzyme. Nimmt so ein Lysosom dann neues Material auf, das verdaut werden soll, so nennt man diese dann sekundäre Lysosomen.
+- Sind <one>Membranen einer Zelle</one> <two>Polymere</two>? <one>Nein</one> - Membranen sind <two>Aggregate</two>.
+- How do we call <one>the vesicles</one> derived from the <three>ER</three>? <one>Microsomes</one>.
+- <one>What</one> does the cyclosome/anaphase promoting complex degrade? It degrades the <one>anaphase inhibitor</one>, via the <two>ubiquitin-degradation pathway</two>.
+- <one>Which protein</one> <two>separates</two> Ran-GTP from importin? The <one>RanBP</one> (<two>Ran Binding Protein</two>).
+- Nenne ein Protein, das an das <one>ER-Retentionssequenz</one> <two>KDEL</two> bindet. A: <one>BiP</one>. URL: https://www.ncbi.nlm.nih.gov/pubmed/28769758
+- An <one>amoeba</one> (a single-celled protozoan) can have <two>a cell diameter of approximately ... </two>? <one>0.5 mm</one>.
+- <one>Where</one> do we find the <two>SRP-Receptor</two>? In the <one>ER membrane</one>.
+- In general: <one>most cell lines used in cell culture technology were derived from</one>? From <one>tumors</one>.
+- <one>How</one> was the function of the <two>SRP</two> (Signal recognition particle) discovered? By the study of processed and unprocessed immunoglobulin light chains.
+- <one>Eine bakterielle Zelle</one> <two>besitzt wieviele Moleküle ATP</two>? <one>1 Million</one>.
+- Some <one>adhesive interactions</one> are adhesive, but why is this valid for the tendons? Because the connective tissue of tendons must transmit force to the skeleton.
+- Zusätzlich zu den <one>Motorproteinen</one> stellen <two>zytoplasmatische Verbindungsproteine</two> eine Verbindung her, zwischen Mikrotubuli und anderen Zellorganellen. <three>Wie werden diese Proteine genannt</three>? <one>CLIPS</one> (<two>cytoplasmic linker proteins</two>).
+- In cell biology: <one>where</one> may one be able to find a <two>lagging head</two>? Within the cell, in <one>kinesin</one>.
+- <one>Intermediärfilamente</one> können mit anderen Intermediärfilamenten eine Interaktion eingehen. <two>Wie geschieht dies</two>? Über <one>Heptad-Repeats</one>.
+- Wozu braucht die Zelle <one>Mikrotubuli</one>? <one>Mikrotubuli</one> funktionieren wie <two>Schienen</two>, entlang derer Mitochondrien, Chloroplasten, Vesikel, Proteine und mRNA transportiert werden kann.
+- Name <one>three general roles</one> of <two>actin filaments</two>. A: (1) cellular contraction (2) <one>cellular migration</one> (3) <one>signalling</one>
+- <one>Welches Protein</one> <two>spaltet Vesikel in einer Zelle ab</two>? <one>Dynamin</one>. URL: https://en.wikipedia.org/wiki/Dynamin
+- Is <one>membrane synthesis</one>, for a given cell, <two>templated by a parental structure</two>? <one>Yes</one>, always.
+- Die <one>Rab Proteinfamilie</one> haben allgemein <two>wieviele Untereinheiten</two>? <one>Eine</one>.
+- <one>Welches Enzym</one> erzeugt <two>dTMP</two>? <one>Thymidylate Synthetase</one> (ausgehend von dUMP).
+- Is <one>robustness</one> <two>in biological systems</two> always a good thing? <one>No</one>. <two>A robust cancer cell is NOT a good thing for the patient!</two>
+- The <one>clathrin triskelion</one> is specifically made up of ... ? <one>3 light chains</one> - and <one>3 heavy chains</one>.
+- <one>Schleiden</one> and <one>Schwann</one> proposed the <two>cell doctrine</two> in which year? In the year <one>1838</one>.
+- <one>Plant RNA editing</one> <two>modifies what to what</two>? Plant RNA editing modifies <one>cytidines</one> (C) to <one>uridines</one> (<two>U</two>), at specific sites in the transcripts.
+- <one>Welche zwei Proteine</one> sind für die <two>Stabilität des Zellkerns</two> einer eukaryoten Zelle extrem wichtig? (1) <one>Typ-A-Lamin</one> (2) <one>Typ-B-Lamin</one>
+- In der molekularen Zellbiologie: was ist <one>Wee1</one>? <one>Wee1</one> ist eine <two>nuclear kinase</two> (ist also im Zellkern vorzufinden), die zur Ser/Thr Familie der Proteinkinasen gehört, in der fission yeast "Schizosaccharomyces pombe". Die molekulare Masse ist 96 kDa. Ihre Aufgabe ist es den Verlauf des Zellzyklus zu regulieren. Zudem kann es die Zellgrösse beeinflussen, indem sie den Eintritt in die Mitose verzögert, durch hemmende Interaktion mit Cdk1- daher der Name "Wee".
+- Nenne eine Grenze der Lichtmikroskopie. A: Die <one>Abbe-Grenze</one>. URL: https://de.wikipedia.org/wiki/Aufl%C3%B6sung_(Mikroskopie)#Abbe-Limit
+- Nenne <one>die drei Typen von Membranrezeptoren</one>. A: (1) G-Protein gekoppelte Rezeptoren (2) Rezeptortyrosinkinasen (3) Liganden-gesteuerte Ionenkanäle
+- Der Mensch hat wieviele Zellen? <one>10¹⁴</one>.
+- Name the <one>two classes</one> of <two>microtubule-based motors</two>. A: (1) <one>Dynein</one> (2) <one>Kinesin</one>
+- How are the cells - in general - be called that secrete their own signals into the bloodstream? <one>Endocrine cells</one>. These cells will <two>secrete hormones</two>.
+- What is the <one>primary function</one> for <two>intermediate filaments</two> for a cell? To <one>provide mechanical strength</one>.
+- <one>Welche Cytoskelett-Elemente</one> sind <two>apolar</two>? Nur die <one>Intermediärfiamente</one>.
+- <one>Centrioles</one> are essential for development of ... ? <two>cilia</two> and <two>flagella</two>.
+- Nenne ein <one>Kompartiment</one>, das man nur in (manchen) Eukarya findet - ausgenommen <two>Chloroplasten</two>, <two>Nucleus</two> und <two>Mitochondrien</two>. A: Die <one>pulsierende Vakuole</one>.
+- The main phospholipids in most animal cell membranes are ...? The <one>phosphoglycerides</one>, also called <two>glycerophospholipids</two>. URL: https://en.wikipedia.org/wiki/Glycerophospholipid
+- <one>Ras proteins in the cytoplasm</one> tend to have what at their carboxy termini? <one>Lipid groups</one>.
+- <one>Where inside of a cell</one> can we find the <two>Cajal bodies</two>? In the <one>nucleus</one>.
+- The <one>Integral of viable cells</one> (IVC) is required for determination of <two>cell-specific rates</two>. It is calculated from ... ? The <one>growth curve</one>.
+- In cell biology, in the <one>chaperone-mediated variant of autophagy pathway</one>: <two>which complex</two> is the most important one? The <one>hsc70-containing complex</one>.
+- Die gängige Bezeichnung für <one>Mitochondrien</one> ist ... ? <one>Kraftwerke der Zelle</one>.
+- Inside cilia there is a <one>microtubule-based cytoskeleton</one>. <two>What is its name</two>? The <one>axoneme</one>. URL: https://en.wikipedia.org/wiki/Axoneme
+- What do the <one>MPRs</one> (<two>Mannose 6-Phosphate Receptors</two>) bind? <one>MPRs</one> bind to newly synthesized lysosomal hydrolases in the trans-Golgi network (TGN) and deliver them to pre-lysosomal compartments.
+- <one>Autophagy</one> is induced <two>upon nutrient depletion</two> - or alternatively, <three>treatment with which particular drug</three>? With <one>Rapamycin</one>.
+- Give another term for the <one>Protein kinase A</one>. A: <one>cAMP-dependent protein kinase</one>.
+- Name <one>an enzyme</one> that helps in <two>protein folding</two>. A: The <one>protein disulfide isomerase</one>.
+- <one>G-Proteine</one> besitzen <two>drei Untereinheiten</two>. Wie können wir experimentell die Alpha-Untereinheit dauerhaft binden und somit einen Effektor blockieren oder dauerhaft aktivieren? Durch Gabe von <one>schwefelsubstituiertem GTP</one>.
+- Nenne <one>drei Typen</one> an <two>Membranproteinen</two>. A: (1) <one>peripher</one> (2) <one>integral</one> (3) <one>glykolipid-verankert</one>
+- What does <one>phagocytosis</one> literally mean? <one>Cellular eating</one>. URL: https://en.wikipedia.org/wiki/Phagocytosis
+- What is the purpose of the <one>caveolae</one> within a given cell? They <one>can protect a cell from stretching</one>. (<two>Caveola mechanosensing</two>)
+- <one>NSF</one> is an <two>ATPase</two>, involved in membrane fusion. How many subunits does it have? <one>NSF</one> is <two>homohexameric</two>, so it has <three>six subunits</three>.
+- Name <one>two</one> <two>ER-resident chaperones</two>. A: (1) <one>Calnexin</one> (2) <one>Calreticulin</one>
+- What is <one>Transdifferentiation</one>? <one>Transdifferentiation</one> is <two>the conversion of a differentiated cell type into another differentiated cell type</two>.
+- Was heißt <one>die Zellmembran ist asymmetrisch</one> ganz konkret, mit Beispiel? Nehmen wir das Mitochondrium heran - Cytochrom c der Atmungskette ist aussen, ATP-Synthase ist innen.
+- In der Zelle führt die <one>TPST</one> (<one>tyrosylprotein sulfotransferase</one>) im Golgi Apparat <two>Sulfonierungen</two> (Sulfation) durch. <three>Woher stammt aber der Schwefel</three>? Der Schwefel stammt von <one>PAPS</one> (<one>3'-Phosphoadenosine-5-Strich-Phosphosulfate</one>).
+- What is the main task of <one>SNARE proteins</one>? <one>SNARE proteins</one> mediate <two>fusion of lipid bilayers</two>.
+- <one>Telomere fusion</one> may, in general, lead to ... ? <one>Chromosomal instability</one>. URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1993879/
+- Name <one>a domain</one> in an <two>initiator procaspase</two>. A: <one>CARD</one> - the <two>Caspase recruitment domain</two>.
+- Aus welchen <one>vier Untereinheiten</one> besteht <two>Cohesin</two>? (1) <one>SMC1</one> (2) <one>SMC3</one> (3) <one>Scc1</one> (4) <one>Scc3</one>
+- <one>Wo</one> kann das Protein <two>RanGAP1</two> gefunden werden? Auf der <one>Außenseite des Zellkern</one>.
+- What is <one>the most typical trigger of autophagy</one>? <one>Nutrient starvation</one>. <two>Lack of any type of essential nutrient can induce autophagy</two>. In yeast, nitrogen starvation is the most potent stimulus.
+- Nenne ein (physiologisches) Kriterium, mit dem wir zwischen <one>Nekrose</one> und <one>Apoptosis</one> relativ einfach unterscheiden können. A: Die <one>Nekrose</one> geht mit einer <two>Entzündungsreaktion</two> einher. URL: https://de.wikipedia.org/wiki/Nekrose
+- <one>Proteine</one> können an den Golgi-Komplex gelangen und von dort, über Vesikel, in welche 3 Zielareale gelangen? (1) in <one>Lysosomen</one> (2) an die <two>Plasmamembran</two> (3) "ausserhalb der Zelle"
+- <one>Welche Aufgabe</one> hat das Protein <two>Ran</two>? <one>Ran</one> setzt das Importprotein im Zellkern frei, wenn es in seiner aktiven Form vorliegt (also als Ran/GTP).
+- What is <one>the difference</one> between <two>budding</two> and binary fission? Both are forms of asexual reproduction. Binary Fission is the splitting of the cell with mitosis followed by cytokinesis. Budding is the outgrowth of a new cell from the surface of an old one.
+- Wie nennen wir den <one>G1-Kontrollpunkt</one> in Säugetierzellen? <one>Restriktionspunkt</one> (<two>R-Punkt</two>).
+- <one>Wo genau</one> kann <two>Sphingomyelin</two> gefunden werden? In der <one>Myelinscheidenmembran der neuronalen Axone</one>.
+- <one>What activity</one> does <two>Dynamin</two> have? <one>Dynamin</one> has <two>a GTPase activity</two>. URL: https://en.wikipedia.org/wiki/Dynamin
+- <one>With which technique</one> could we <two>prove that signal sequences in proteins are important</two>? With a <one>transfection experiment</one>.
+- Can <one>a cell</one> regulate the export and import of shuttling proteins? <one>Yes</one>, via phosphorylation-dephosphorylation of residues adjacent to NLS or NES signals, resulting in blockade/exposure of signals.
+- Name one big <one>difference</one> between the lumen of a <two>lysosome</two> and the <two>cytoplasm</two>. A: The lumen of a lysosome is <one>more acidic</one> than the cytoplasm.
+- Nenne <one>ein kleines G-Protein</one> das mit dem Buchstaben <two>A</two> beginnt. A: <one>Arf</one> (<two>ADP ribosylation factors</two>). URL: https://en.wikipedia.org/wiki/ADP_ribosylation_factor
+- In cell biology: what does the abbreviation <one>Nups</one> stand for? <one>Nucleoporins</one>. URL: https://en.wikipedia.org/wiki/Nucleoporin
+- Nenne die <one>drei Komponenten</one> beim Aufbau eines Lipidmoleküls. A: (1) <one>Cholin</one> (2) Phosphat (3) <one>Glycerin</one>
+- <one>Welche zwei Enzyme</one> konvertieren <two>dUTP</two> zu <three>dTTP</three>? (1) <one>Phosphatase</one> (2) <one>Kinase</one>
+- Welche <one>zwei verschiedene Arten</one> von <two>Membrantransport</two> gibt es? (1) Transport durch die Membran hindurch (2) Transport innerhalb der Membran selbst (zum Beispiel Elektronentransport)
+- <one>In welche Richtung</one> wandern jeweils COP I und COP II Vesikel? COP I wandert von trans-Golgi zu cis-Golgi, COP II wandert in die gegengesetzte Richtung also vom rauhen ER hin zum Golgi Apparatus.
+- <one>Proteins can move from one intracellular compartment to another</one>, <two>by which three mechanisms</two>? (1) <one>gated transport</one> (2) <one>protein translocation</one> (3) <one>vesicular transport</one>
+- Name a way how to experimentally measure DNA replication. A: Make use of <one>[3H] thymidine</one>.
+- Was macht das <one>Tus Protein</one>? Das Tus Protein blockiert die <one>DnaB-Helikase</one> und bringt damit die Wanderung der Replikationsgabel zum Stillstand.
+- For any given eukaryotic cell: <one>when</one> is <two>supercoiling</two> extremely important? When it comes to the <one>replication of DNA</one>.
+- <one>What happens</one> when we increase the concentration of detergents above the CMC? Some of the <one>detergent molecules</one> will form <two>micelles</two>.
+- The Adaptor protein <one>Epsin</one> in a cell helps which other molecule? <one>Clathrin</one>.
+- <one>Who</one> has a <two>DEAD box motif</two>? <one>RNA Helicases</one>.
+- A single <one>gap junction channel</one> is <two>composed of two ... </two>? <one>Connexons</one>. URL: https://en.wikipedia.org/wiki/Connexon
+- Nenne einen Hemmer von <one>MDM2</one>. A: Das <one>Arf-Gen Produkt</one>.
+- <one>Welche Aufgabe</one> haben die <two>Cajal-Körper</two>? Sie synthetisieren kleine Kern-RNAs (<one>small nuclear RNAs</one>).
+- <one>Wie</one> entsteht ein <two>Autolysosom</two>? Durch <one>Fusion</one> eines <two>Lysosom</two> mit einem <two>Autophagosom</two>.
+- Name <one>two</one> <two>microtubule organizing centers</two>. A: (1) <one>centrosome</one> (2) <one>centrioles</one>
+- <one>Clathrin</one> besteht aus? 3 leichten und 3 schweren Ketten. URL: https://de.wikipedia.org/wiki/Clathrin
+- Name something in a cell that is <one>bipolar</one>. A: The <one>mitotic spindle</one>, also called <two>the spindle apparatus</two>. URL: https://en.wikipedia.org/wiki/Spindle_apparatus
+- Name <one>a trivial difference</one> between a <two>late endosome</two> and an <two>early endosome</two>. A: A <one>late endosome</one> <two>is larger than</two> the <three>early endosome</three> - thus, <four>size is a key difference here</four>.
+- <one>Wann</one> wurde das <two>Fluid-Mosaic-Modell</two> vorgeschlagen? <one>1972</one>.
+- <one>Pro Sekunde</one> produziert ein erwachsener Mensch wieviele Erythrocyten? About <one>2.000.000</one>.
+- Nenne <one>zwei viel verwendete Detergenzien</one> für beziehungsweise gegen eine <two>biologische Membran</two>. A: (1) <one>Triton X-1000</one> (2) <one>Natriumdodecylsulfat</one>
+- For its synthesis, <one>Cyclin D</one> <two>requires which specific transcription factor</two>? <one>E2F</one>.
+- Welches <one>radioaktive Isotop</one> kann genutzt werden, um die Teilungsaktivität von proliferierenden Zellen zu beobachten? <one>P³²</one>.
+- Angenommen wir sehen <one>zwei Zellen</one> - eine kleinere Zelle und eine größere Zelle. Wir wissen das eine davon eine Stammzelle sein muss. Welche würden wir dann annehmen wäre die Stammzelle? Die größere der beiden Zellen.
+- In der Zellbiologie ist eine <one>Darmepithelzelle</one> ein Beispiel für eine <two>polarisierte Zelle</two>. Welche drei Seiten können wir hier unterscheiden? (1) <one>Apikal</one> (2) <one>Lateral</one> (3) <one>Basal</one>
+- Can <one>Integrins</one> bind to <two>fibronectin</two>? <one>Yes</one>.
+- Give an example for <one>gated transport</one> in cell biology. A: The transfer of material through <one>nuclear pore complexes</one>.
+- What is meant with the expression <one>non-bilayer lipids</one>? These are lipids that can not build a bilayer of lipids.
+- Give another (<i>fancier</i>) term for <one>phagocytosis</one>. A: <one>Cellular cannibalism</one>.
+- <one>cdc42</one> <two>belongs to which family</two>? The <one>Rho family</one>.
+- Warum heissen <one>G-Proteine</one> so (das <one>G</one> in ihrem Namen)? Weil sie <one>Guanin-Nukleotide</one> binden.
+- <one>Phospholipid molecules</one> also include <two>choline</two>. Is choline hydrophilic or hydrophobic? Choline is fairly <one>hydropholic</one>; it is part of the hydrophilic head group of phospholipids as well.
+- Wieso kann <one>Chlorophyll</one> mit Lipiden assoziieren? Weil es eine <one>Alkoholseitenkette</one> besitzt.
+- <one>How many nucleosomes</one> does <two>a single, diploid human cell have</two>? It should have about <one>30 million nucleosomes</one>.
+- <one>What cellular effect</one> may be caused by a <two>phenobarbital-treatment</two>? This will <one>stimulate liver cell division</one> - and thereby <two>liver enlargement</two>.
+- An <one>animal cell</one> <two>contains about n protein molecules</two>? 10¹⁰ protein molecules.
+- <one>Cadherins</one> are linked to the <two>actin cytoskeleton</two> by ...? <one>Catenins</one>.
+- In cellbiology: what is <one>Dynamin</one>? <one>Dynamin</one> is <two>a large GTPase</two>, involved in the scission of nascent vesicles from parent membranes.
+- <one>The longest cells</one> are typically ... ? <one>Nerve cells</one>, aka <two>neurons</two>. <three>Some of these neurons stretch from spine to toe</three>.
+- In humans: <one>Phospholipase C</one> <two>activates which cellular enzyme</two>? <one>Proteinkinase C</one>. URL: https://en.wikipedia.org/wiki/Phospholipase_C#Biological_function
+- <one>How</one> was <two>autophagy</two> initially called? <one>Autolysis</one>.
+- <one>Inositol phospholipids</one> can be <two>phosphorylated at how many positions</two>? <one>3</one> - at <two>3'</two>, <two>4</two>' and <two>5</two>'.
+- <one>Superresolution microscopy</one> <two>may resolve the wavelength range from n nm to n nm</two>? From about <one>40nm</one> to <one>120nm</one>, give or take.
+- <one>Wann</one> wurde der <two>Golgi-Apparat</two> entdeckt? <one>1898</one>.
+- Was ist ein <one>Tendinozyt</one>? Ein <one>Tendinozyt</one> ist eine Fibroblastenart, die im straffen kollagenen parallelfaserigen Bindegewebe von Sehnen vorkommt.
+- <one>Welche Zellen</one> besitzen viel an <two>Albumin-mRNA</two>? <one>Hepatocyten</one>. URL: https://en.wikipedia.org/wiki/Hepatocyte
+- Nenne <one>ein Protein das den Zellzyklus blockieren kann</one>. A: <one>p21</one>.
+- For the <one>retention of a protein in the lumen of the ER</one>, <two>which three aminoacids are important</two>, linked together? <one>K-D-Q</one>.
+- Nenne die <one>vier Bewegungsmöglichkeiten von Phospholipiden</one>. A: (1) "flexion" (2) "rotation" (3) "laterale Diffusion" (4) <one>transversale Diffusion</o
+- <one>Which organelle</one> <two>produces Lysosomes</two>? The <one>Golgi Apparatus</one>. URL: https://en.wikipedia.org/wiki/Golgi_apparatus
+- <one>Mikrotubuli</one> besitzen eine polare Struktur. Welchen funktioniellen Unterschied gibt es zwischen dem +-Ende und dem -Ende? Das plus-Ende hat eine höhere Geschwindigkeit für Ein- und Abbau von Untereinheiten. Am minus-Ende erfolgt der bevorzugte Abbau.
+- <one>Welche Aufgabe</one> hat das <two>Tat protein export system</two> und was heisst <three>tat</three> überhaupt? <one>tat</one> heißt <two>twin arginine translocase</two>. Es transportiert gefaltete Proteine aus dem Cytoplasma hinaus.
+- What is the <one>coatomer</one> in cell biology? The <one>coatomer</one> is <two>a protein complex that coats membrane-bound transport vesicles</two>.
+- The <one>KDEL sequence</one> <two>in peptides</two> is located on the N-terminus or the C-terminus? It is located on the <one>C-Terminus</one> of an amino acid sequence of a protein.
+- Wenn wir <one>Nocodazol</one> zu Zellen geben, <two>was passiert dann</two>? <one>Arrest in der Mitose</one>.
+- Give an example for a <one>quaternary RNA Structure</one>. A: The <one>ribosome</one>.
+- <one>Welches Protein</one> ist <two>Bestandteil der Centrosomen</two>? <one>Gamma-Tubulin</one>. URL: https://de.wikipedia.org/wiki/Tubuline#.CE.B3-Tubulin
+- <one>Welche Aufgabe</one> haben die <two>RAB-Proteine</two> in der Zelle? Sie überprüfen die Spezifität des Andockens eines Vesikels an die Zielorganelle.
+- Give another word for a normally shaped <one>red blood cell</one>. A: A <one>discocyte</one>.
+- Welche <one>zwei wichtige Aufgaben</one> hat <two>Ran</two>/<two>GTP</two>? <one>RanGTP</one> hilft beim Import und Export von Proteinen in und aus dem Nukleus.
+- <one>Welche drei Kräfte</one> dominieren bei der <two>Ligandenbindung</two>? (1) <one>ionische Wechselwirkungen</one> (2) <one>van-der-Waals-Kräfte</one> (3) <one>Wasserstoffbrücken</one>
+- What is a <one>clonogenic assay</one>? A <one>clonogenic assay</one> is <two>a cell biology technique for studying the effectiveness of specific agents on the survival and proliferation of cells</two>.
+- Wie kann man die <one>Mitose</one> <two>genetisch ausschalten</two>? Durch <one>Deletion des Centromers</one>.
+- Name <one>a protein</one> that can <two>severe actin filaments</two>. A: <one>Gelsolin</one>. URL: https://en.wikipedia.org/wiki/Gelsolin
+- Was heisst <one>ERAD</one> in der Zellbiologie? <one>ER-associated degradation</one>. URL: https://en.wikipedia.org/wiki/Endoplasmic-reticulum-associated_protein_degradation
+- Nenne ein Beispiel für einen <one>bidirektionalen Rezeptor</one> der Zelle. A: <one>Integrine</one>.
+- Allgemein formuliert: <one>welche Zellen sind vor allem in der G0 Phase</one>? <one>Ausdifferenzierte Zellen</one>.
+- Is <one>lampbrush DNA</one> <two>special</two>? <one>Yes</one>. The DNA in these lampbrush loops appears to be <one>transcriptionally active</one>, while the majority of DNA in axis is inactive.
+- <one>A human cell</one> has <two>a typical diameter of n micrometres</two>? <one>20 micrometres</one>.
+- In cell biology: what is meant with the abbreviation <one>INM</one>? <one>Inner nuclear membrane</one>.
+- Bei der <one>Renaturierung von DNA</one> benötigen wir <two>warum</two> eine <three>hohe Salzkonzentration</three>? Um die negativen Ladungen der Phosphatgruppen der DNA zu neutralisieren.
+- <one>Paired strands of RNA</one> are arranged how ...? <one>Antiparallel</one>.
+- Why the name <one>cadherin</one>? <one>Cadherin</one> depend on Ca²⁺ ions - removing Ca²⁺ from the extracellular medium causes adhesion mediated by cadherin to come apart.
+- <one>Cells</one> contain <two>extensive sets of intracellular membranes</two>. <three>Together these are called the ... </three>? The <one>endomembrane system</one>. URL: https://en.wikipedia.org/wiki/Endomembrane_system
+- What does a <one>secretory protein</one> truly hate? The <one>cell membrane</one>.
+- <one>How</one> can a cell make sense of many different (external) signals? It can respond to these signals selectively by <one>selectively expressing appropriate receptors</one>.
+- Name <one>an advantage of optical microscopy</one>, in regards to visualizing biological systems. A: <one>Light</one> is relatively <two>nondestructive</two>.
+- <one>What type of light</one> <two>is used in microbiology</two>? <one>Visible light</one> + <one>UV light</one>.
+- What is the <one>common feature</one> <two>among Golgi</two>? They are adjacent to <one>endoplasmic reticulum (ER) exit sites</one>.
+- Are <one>tetraspanins</one> <two>glycosylated</two>? Some are, at the <one>N-terminus</one>.
+- Name <one>a binding protein for beta 1 integrin</one>. A: <one>Talin</one>.
+- In seiner chemischen Struktur ähnelt <one>Phycocyanin</one> wem? Einem <one>unfolded chlorophyll molecule</one>.
+- Precursor of a <one>lysosome</one>? The <one>late endosome</one>. URL: https://en.wikipedia.org/wiki/Endosome#Late_endosomes_to_lysosomes
+- What are <one>professional phagocytes</one>? (1) <one>macrophages</one> (2) <one>neutrophils</one>
+- Die <one>M-Phase</one> im Zellzyklus <two>wird unterteilt in welche Phasen</two>? (1) <one>Karyokinese</one> (2) <one>Zytokinese</one>
+- <one>Wer</one> etablierte das <two>Flüssig-Mosaik-Modell</two> im Jahre 1972? <one>Singer</one> und <one>Nicolson</one>.
+- Es gibt <one>SUN</one> und <one>KASH</one> Proteine. <two>Wo können diese gefunden werden</two>? KASH-Proteine sind dem Cytosol zugewandt, SUN Proteine dem Nucleus (Merkhilfe: Eine sun sieht dem Nucleus von der Form her ähnlich).
+- The famous protein <one>p53</one> actually does not have a mass of 53 kDa but only 43.7 kDa. Why is that the case? <one>p53</one> has a high number of <two>proline</two> residues, which <three>slow its migration on SDS-PAGE</three>, thus making it <four>appear heavier</four> than it actually is.
+- <one>Cells produce</one> which <two>three types of large macromolecules</two>? (1) <one>polysaccharides</one> (2) <one>proteins</one> (3) <one>nucleic acids</one>
+- Der <one>SRPT</one> wirkt auch als ...? <one>GEF</one> - Guanin nucleotide exchange factor.
+- Consider an <one>integrin</one> that is in an <two>active state</two>. <three>What do we know, then</three>? That this integrin will <one>readily form attachments</one>.
+- <one>How</one> can we <two>visualize lateral diffusion of membrane proteins</two>? Via <one>FRAP</one>: <two>Fluorescent Recovery after Photobleaching</two>.
+- Name <one>three photoproteins</one>. A: (1) <one>Aequorin</one> (2) <one>Obelin</one> (3) <one>Phialidin</one>
+- <one>Why</one> may it be an advantage for eukaryotic cells if they can store secretory proteins in membrane compartments? Because this allows them to release these proteins from the cell surface in response to internal or external signals.
+- <one>Wo</one> befinden sich <two>tSNARE Proteine</two> allgemein? <one>tSNARE Proteine</one> befinden sich in der <two>Membran der Zielorganelle</two>.
+- Give another name for <one>histone writers</one>. A: <one>Histone modifying enzymes</one>.
+- <one>Which Cdc</one> <two>activates the APC</two>/<two>C complex</two>? <one>Cdc20</one>.
+- The <one>endoplasmic reticulum</one> is especially important in the synthesis of ... ? <one>lipids</one>.
+- In cellbiology we make use of the CD system, that is the <one>clusters of differentiation</one> - but <two>how is that CD nomenclature factually established and determined</two>? We need to <one>use monoclonal antibodies</one> here. These can selectively bind to these surface clusters.
+- <one>Membrane bending</one> by ... domains? <one>BAR domains</one>. They can induce different curvatues.
+- <one>Actin</one> macht <two>n% der Proteinmasse in einer eukaryoten Zelle aus</two>? <one>Bis zu 20%</one> der Proteinmasse.
+- Anderes Wort für <one>VCCD</one> (<two>Viable Cumulative Cell Days</two>)? <one>Viability Index</one>.
+- Was geschieht beim <one>Spindel-Checkpoint</one>? Die Zelle <one>überprüft ob alle Chromosomen an Spindeln angehängt sind</one>.
+- Wie schützt die Zelle die <one>Plus-Enden von Mikrotubuli</one> vor Depolymerisation? Durch Verankerung in einem <one>capping Protein</one>. Dies verleiht den Plus-Enden einen Schutz.
+- <one>Which cells</one> produce <two>E-selectin</two>? <one>Endothelial cells</one> will produce <two>E-selectin</two> - but only when stimulated by inflammatory hormones or by endoxotins.
+- Give a shorter word for <one>cytoskeletal linker proteins</one>. A: <one>Cytolinkers</one>.
+- <one>Desmin</one> is a protein, a type III intermediate filament. It can also be found in humans. In which type of cells may we find it? <one>Desmin</one> can be found in <two>muscle cells</two>.
+- Give another term for <one>chaperones</one>. A: <one>Folding proteins</one>.
+- Name a factor that may counteract <one>VEGF</one> (<two>vascular endothelial growth factor</two>). A: <one>Endostatin</one>.
+- Was ist eine <one>isokonte Begeißelung</one>? Wenn eine Zelle <one>mehrere Geißeln</one> trägt.
+- <one>Welche zwei Formen</one> des <two>Co-Transport</two> gibt es für eine Zelle? (1) <one>Symport</one> (2) <one>Antiport</one>
+- <one>Microglia</one> are <two>scavenger cells</two>. <three>What is meant with that term</three>? <one>Scavenger cells</one> are cells that engulf and digests debris, as well as invading microorganisms.
+- The <one>Golgi cisternae stack</one> has which 4 functional regions? (1) the cis-Golgi network (CGN) (2) the medial-Golgi (3) the <two>endo-Golgi</two> (4) the <one>trans-Golgi network</one> (<two>TGN</two>)
+- The <one>SV40 T-Antigen</one> can be imported into the nucleus by <two>importins</two>, thanks to the <one>PPKKKRKV signal sequence</one>. <three>How amenable is said sequence to change</three>? <one>Not very amenable at all</one>. If one lysine is replaced by a threonine, no import will happen at all.
+- <one>Which cells</one> may, in general, <two>be more likely to require autocrine signaling</two>? <one>Cancer cells</one>. They often produce extracellular signals that then simulate their own survival and proliferation.
+- In an electron microscope: name <one>two major differences</one> between "lysosomes" and "peroxisomes". A: (1) lysosomes are smaller (2) Lysosomes appear "darker", hence they are more "electron rich", thus, denser.
+- Andere Bezeichnung für die <one>Oberfläche einer Zelle</one>? <one>Cytoplasmamembran</one>.
+- Name a <one>lipid-soluble second messenger</one>. A: <one>Diacylglycerol</one>. URL: https://en.wikipedia.org/wiki/Diglyceride
+- What is the <one>most fundamental task</one> for a cell? The passing on of its genetic information to the next generation of cells.
+- In cell biology: how do we call the methodological step necessary for releasing organelles? <one>Homogenization step</one>.
+- A single <one>NPC</one> <two>can transport n macromolecules per second</two>? <one>1000</one>.
+- <one>Rab-Proteins</one> are <two>what type of proteins</two> exactly? Rab-Proteins are <one>monomeric GTPases</one>.
+- <one>Wo</one> finden wir eine <two>glykosidische Bindung</two> in einem Nukleotid? Zwischen der <one>Base</one> und dem <one>Zucker</one>.
+- Was meinen wir in der Zellbiologie mit dem <one>retrograden Transport</one>? Dies bezeichnet den Transport von der Zellmembran hin zum Zellkern.
+- Name <one>two components</one> of the <two>ER lumen</two>. A: (1) ER tubules (2) <one>ER sheets</one>
+- Name <one>two general advantages</one> associated with <two>subcellular components</two>. A: (1) <one>concentrate metabolic intermediates</one> (2) <one>sequester toxic compounds</one>
+- Besitzen <one>Pilze</one> <two>Centriolen</two>? <one>Nein</one>.
+- In cellbiology we can see the <one>CVT pathway</one>. <two>This abbreviation stands for ... </two>? <one>Cytoplasm-to-vacuole targeting pathway</one>.
+- <one>Wie groß</one> (<two>in nm</two>; von-bis) sind die <three>caveolae</three>? <one>50-100 nm</one>.
+- What exactly is a <one>neoplasm</one>? A <one>neoplasm</one> is an accumulation of <two>abnormally dividing cells</two>.
+- In der Zellbiologie: was sind <one>reticulons</one>? <one>Reticulons</one> sind <two>membranständige Proteine, die das tubuläre endoplasmic reticulum (ER) bilden</two>.
+- Anderer Name für <one>importin-beta-like protein</one>? Karyopherin-Beta-family.
+- Give another name for <one>how cells move</one>. A: <one>Cell motility</one>. URL: https://en.wikipedia.org/wiki/Cell_migration
+- Innerhalb der Zelle: <one>wo</one> spielen <two>Actinfilamente</two> eine Rolle? Sie bilden dynamische Netze unterhalb der Zellmembran.
+- <one>Wo</one> innerhalb der Zelle findet man die <two>zelluläre Phosphotransferase</two>? Dies ist <one>ein Enzym des Golgi apparatus</one>.
+- The protein <one>Dysferlin</one> is linked to which cellular function ...? To <one>skeletal muscle repair</one>.
+- How do we call <one>the disc-like compartments of the Golgi apparatus</one>? <one>Golgi cisternae</one>.
+- <one>Karyopherins</one> are, or can be broadly grouped into, ...? (1) <one>importins</one> (2) <one>exportins</one>
+- Name <one>a protein</one> that <two>can dissociate SNARE pairs</two>. A: <one>NSF</one>.
+- Im Zellkern: nenne ein Protein, das an <one>Importin</one> bindet. A: Das monomere G-Protein <one>Ran</one>. URL: https://en.wikipedia.org/wiki/Ran_%28gene%29
+- Was enthält das <one>Peroxisom</one>? Enzyme, die <one>H₂O₂</one> bilden und abbauen kann.
+- Give another name for <one>DNA-protein intermediary</one>. A: <one>RNA</one>.
+- Ist <one>Myoglobin</one> <two>an intrazellulären Prozessen beteiligt</two>? <one>Ja</one> - und zwar am <two>intrazellulären O₂-Transport</two>.
+- <one>Welche Aufgaben</one> hat <two>das raue ER</two>, <one>welche Aufgaben</one> hat <two>das glatte ER</two>? (1) Aufgaben des rauen ER:   Synthese von Membran-, Export- und Lysosomenproteinen (2) Aufgaben des glatten ER: <one>Lipidsynthese</one>
+- Name <one>an organism</one> <two>in which cilia assemble in the cytoplasm</two>. A: <one>Plasmodium falciparum</one>.
+- If we wish to add a <one>fluorescent dye</one> <two>to Tubulin</two>, which one should we use? <one>Rhodamine</one>.
+- When <one>lipids</one> go below the paracrystalline temperature, what do they <two>lose</two>? The ability to <one>rotate</one>.
+- Name one famous <one>cellular Cdk inhibitor</one>. A: <one>p21</one>.
+- What effect may <one>TGF-Beta</one> have on cells? <one>TGF-Beta</one> may <two>force a halt to proliferation</two>.
+- Nenne <one>drei Wachstumsfaktoren</one> inklusive ihres vollen Namens. A: (1) PDGF: Plateled Derived Growth Factor (2) VEGF: Vascular Endothelian Growth Factor (3) <one>EGF</one>:  <two>Epidermal Growth Factor</two>
+- Im Jahre <one>2015</one> waren etwa <two>wieviele</two> <three>kleine G-Proteine</three> bekannt? Etwa <one>100</one>.
+- <one>Nitric oxide</one> (NO) has an impact on which part of the Mitochondria? On <one>complex IV</one>, which is <two>cytochrome c oxidase</two>.
+- Was meinen wir in der angewandten Zellbiologie mit <one>"quantum dots"</one> eigentlich? Hier sind primär <one>fluoreszierende Nanopartikel</one> gemeint.
+- When a protein does not have a <one>sorting signal</one>, what will be the result? Such a protein will <one>permanently reside in the cytosol</one>.
+- <one>Coated pits</one> <two>give rise to which structure</two>? <one>Coated vesicles</one>.
+- In the cell: <one>tethering proteins of the membrane</one> do <two>recognize which proteins</two>? They recognize <one>Rab proteins</one>.
+- How are <one>lysosomal hydrolases</one> <two>tagged</two> in the Golgi apparatus? Via <one>mannose-6-phosphate</one> groups.
+- The <one>LDL-LDLR endocytosis pathway</one> begins with sequestering the LDL-LDLR complex on the cell surface into ... ? <one>clathrin-coated pits</one>.
+- Was ist <one>Transmission</one> in der Mikroskopie? Transmission bezeichnet <one>das Durchdringen eines Objektes mit Licht</one>.
+- Wie können wir die <one>Phosphodiesterase</one> hemmen? Durch <one>Koffein</one>. URL: https://de.wikipedia.org/wiki/Coffein#Wirkungsmechanismus
+- Andere Bezeichnung für <one>Glykoprotein der Zelloberfläche</one>? <one>Aggregationsfaktoren</one>.
+- <one>Who</one> are the most complex <two>glycolipids</two>? The <one>gangliosides</one>.
+- Name <one>a small molecule inhibitor of Dynamin</one> that also begins with the letter <two>D</two>. A: <one>Dynasore</one>.
+- <one>Wie</one> bezeichnen wir die Diffusion durch eine Membran? <one>Passiver Transport</one>.
+- What is a <one>Heteroplasmon</one>? This is an eukaryotic cell in which both wild-type and mutant organelle DNA coexist. Sometimes also called a cytohet. URL: https://en.wikipedia.org/wiki/Cytohet
+- Eine <one>aktive Muskelzelle</one> <two>regeneriert pro Sekunde wieviel ATP Moleküle</two>? <one>10 Millionen</one>.
+- What is the <one>end stage</one> of an <two>autolysosome</two>? A <one>residual body</one>.
+- <one>Eps15</one> in der Zelle ist ein <two>multifunctional adaptor protein</two>. Welche Aufgabe hat dies? Reguliert <one>intracellular trafficking</one>.
+- What is the <one>glycosome</one>? The <one>glycosome</one> is a membrane-enclosed organelle that <two>contains glycolytic enzymes</two>.
+- Die Funktion der Energiespeicherung in einer eukaryoten Zelle übernimmt ... ? <one>ATP</one>.
+- <one>Adrenalin</one> bindet an eine Leberzelle. Effekt innerhalb dieser Zelle? Die <one>Glykogenphosphorylase wird aktiviert</one>.
+- What happens if we treat a <one>rat</one> with the drug <two>phenobarbitol</two>? <one>This drug stimulates liver cell division</one>, thereby <two>causing</two> <three>liver enlargement</three>.
+- <one>Wo</one> kann <two>Rab-GTP</two> gefunden werden? An einem <one>Vesikel</one>.
+- <one>Which genes</one> are required for the <two>autophagic pathway</two>? <one>Atg-genes</one>.
+- What is the <one>time hormone</one>? <one>Melatonin</one>. URL: https://en.wikipedia.org/wiki/Melatonin
+- Das <one>KDEL Sequenz</one> am C-Terminus von Proteinen spielt eine wichtige Rolle beim Transport in den ER hinein. <two>Gibt es einen KDEL Rezeptor</two>? <one>Ja</one>, das <two>salvage compartment</two>, als Teil der ER Membran.
+- <one>Menschliche Zellen</one> haben typischerweise einen <two>Zellkern</two>, ausgenommen ... ? Ausgenommen der <one>roten Blutkörperchen</one>. URL: https://de.wikipedia.org/wiki/Erythrozyt
+- How do <one>wee-mutants</one> look in general? Wee-mutants are <one>very small</one>.
+- Anteil von <one>Calmodulin</one> <two>in %</two> an der Proteinmasse in einer typischen eukaryoten Zelle? <one>1%</one>.
+- <one>Wo</one> finden wir den <two>Intermembranraum</two> eines Mitochondriums? Zwischen der äusseren und der inneren Membran.
+- In der Zellbiologie: wofür steht die Abkürzung <one>SNARE</one>? <one>SNAP-(Soluble NSF Attachment Protein)-REceptor</one>. Wenn man das NSF auch noch ausschreibt so kommt man auf "Soluble N-ethylmaleimide-sensitive-factor Attachment Receptor".
+- <one>Detergents</one> <two>are soluble in which specific medium</two>? In <one>water</one>.
+- The <one>conserved building blocks of all cellular membranes are ... </one>? The <one>phospholipids</one>.
+- In der Zellbiologie gibt es die <one>Microbodies</one>. <two>Was wird damit bezeichnet</two>? (1) <one>Peroxisomen</one> (2) <one>Glyoxisomen</one> (3) <one>Glykosomen</one>
+- <one>Which protein</one> <two>assembles new nucleosomes</two>? <one>CAF-1</one> - the <two>chromatin assembly factor</two>. URL: https://en.wikipedia.org/wiki/CAF-1
+- Wie wirkt das Gift <one>Phalloidin</one>? <one>Phalloidin</one> stabilisiert Aktinfilamente, die dadurch ihre Dynamik verlieren.
+- <one>Who</one> and <two>when</two> published the molecular structure of the first nucleotide? <one>Furbery</one>, <two>1951</two>.
+- What does the name <one>Ras</one> - an abbreviation - stand for? <one>Ras</one> is an abbreviation of <two>Rat sarcoma</two>.
+- Inside of a given cell, <one>where</one> may the protein <two>Profilin</two> be found? It can be found <one>bound to an actin monomer</one>.
+- In der Zellbiologie: was ist <one>3D5</one>? Eine <one>tetracycline inducible transfectant cell line</one>.
+- Name the <one>two main classes of membrane proteins</one> that <two>mediate transmembrane traffic</two>. A: (1) <one>transporters</one> (2) <one>channels</one>
+- Name a way how <one>lipid rafts</one> can be observed. A: Via <one>AFM</one> (<two>Atomic Force Microscopy</two>). URL: https://en.wikipedia.org/wiki/Atomic_force_microscopy
+- Name <one>two ways</one> how proteins to be exported can be identified by the cell. A: (1) SecA protein (2) signal recognition particles (SRP)
+- Give another name for a <one>nucleotid</one>. A: <one>Nucleoside-5'-Phosphate</one>.
+- Another term for <one>the translocon</one>? <one>Protein-conducting channel</one>.
+- <one>KDEL</one> ist ein intrazelluläres <two>retention signal</two> für das ER. <three>Aber wie hat man dies nachweisen können, experimentell</three>? Durch <one>in-vitro Mutagenese</one>.
+- Give another name for the <one>Tay-sachs disease</one>? <one>GM2 gangliosidosis</one>.
+- <one>Clathrin</one> is <two>a coating protein</two>. It is associated with proteins, which connect clathrin to vesicle membrane. <three>How are these latter proteins called</three>? <one>Adaptins</one>.
+- <one>Was</one> kann man mit <two>Inhibitors</two> und <two>Uncouplers</two> demonstrieren? Den <one>Elektronenfluss</one> durch Zellkomplexe wie ATPase.
+- <one>Wo</one> befindet sich der <two>Golgi-Apparat</two> und welche Aufgabe hat er? Der <one>Golgi-Apparat</one> befindet sich in der Nähe des ER. Er ist für die Modifizierung und Sortierung von Proteinen verantwortlich.
+- <one>Wer</one> stellte die <two>Zelltheorie</two> auf? <one>Matthias Schleiden</one> und <one>Theodor Schwann</one>.
+- <one>In welche Kategorie</one> fallen <two>I-Cell diseases</two>? <one>Lysosomal storage diseases</one>.
+- <one>Wann</one> genau bildet sich der synaptonemale Komplex? Im <one>Zygotän</one>.
+- In cellbiology: what is <one>Shibire</one>? This is a <one>temperature sensitive phenotype</one> <two>in Drosophila</two>.
+- Who or what can produce <one>transit amplifying cells</one>? <one>Stem cells</one> can.
+- Nenne ein Enzym, das beim lysosomalen Proteinabbau Verwendung findet. A: <one>Cathepsin</one>. URL: https://de.wikipedia.org/wiki/Cathepsine
+- <one>Cell membranes</one> prevent passage of which type of molecules, aside from the size of that molecule? <one>Polar molecules</one>.
+- <one>Ran-GTP</one> can bind to ... ? <one>Importin</one>.
+- What defines the <one>character of a cellular compartment</one>? The <one>composition of the enclosing membrane</one>.
+- How do we call the three <one>MAP-Kinases</one> in mammalian cells? (1) <one>Raf</one> (2) <one>Mek</one> (3) <one>Erk</one>
+- Why do we make use of the <one>Yeast-one-hybrid system</one>? To study <one>protein-DNA interactions</one>.
+- Can <one>Integrins</one> bind to a variety of different ligands? Yes.
+- In cell biology: what does <one>Nups</one> stand for? <one>Nucleoporins</one>.
+- <one>Wo</one> in der Zelle finden <two>N-Glykosylierung</two> und <two>O-Glykosylierung</two> statt? (1) Die <one>O-Glykosylierung</one> findet <two>nur im Golgikomplex</two> statt. (2) Die <one>N-Glykosylierung</one> <two>beginnt im ER und wird im Golgi-Komplex fortgeführt</two>.
+- Why was the name <one>Rab</one> chosen for the <two>Rab proteins</two>? <one>Rab</one>: <two>Rat sarcoma-related in brain</two> proteins.
+- <one>Who</one> initiates the <two>metaphase-to-anaphase</two> transition? The <one>APC</one>/<one>C complex</one>.
+- Welche <one>drei Aussagen</one> trifft <two>die erweiterte Cell Theory</two> von Robert Hooke? (1) All organisms are composed of cells. (2) Cells are the smallest living things. (3) Cells arise only from pre-existing cells.
+- Give an example for a <one>single-pass transmembrane protein</one>. A: The <one>LDL-Receptor</one>.
+- The alkaloid <one>colchicine</one> was <two>first described as a mitotic poison in what year</two>? In the year <one>1934</one>.
+- Im rauhen <one>cytoplasmatischen Retikulum</one>: <two>wo findet man die Ribosomen</two>? Auf der <one>Cytosol-Seite</one>.
+- Was ist <one>spectral tuning</one>? <one>Spectral tuning</one> bedeutet, das verschiedene Pigment-Spektren, sowie andere Faktoren, die diese beeinflussen, durch den Organismus, der diese produziert, adaptiert werden. Also quasi eine "Anpassung an Licht verschiedener Wellenlänge".
+- Give an example from cellbiology where transient interactions with the ECM is important. A: At sites of inflammation, leukocytes bind transiently to endothelial cells lining small blood vessels, before then using transient interactions with the ECM to migrate through connective tissue.
+- <one>Which two classes</one> of <two>apoptotic caspases</two> exist? (1) initiator caspases (2) <one>executioner caspases</one>
+- Name a <one>protein</one> that has a <two>pleckstrin homology domain</two>. A: <one>Dynamin</one>. URL: https://en.wikipedia.org/wiki/Dynamin#Structure
+- What is the main signal for protein delivery into lysosomes via endosomes? The <one>Mannose 6-Phosphate Receptor (MPR)</one>.
+- Name <one>two different forms</one> of <two>cell senescence</two>. A: (1) <one>replicative senescence</one> (2) <one>induced     senescence</one>
+- <one>Welches Protein</one> <two>dissoziiert vSNARE</two>/<two>tSNARE Komplex</two>? <one>NSF</one> (unter ATP Verbrauch).
+- We may wish to <one>determine the concentration of dead cells</one>. <two>How to do so, experimentally</two>? We stain via <one>trypanblue</one>, which is a <two>dye exclusion methods</two>.
+- Name <one>three functions of autophagy</one>. A: (1) starvation (recycling of nutrients) (2) protein aggregation (neurodegenerative importance) (3) damaged organelles
+- The <one>RING finger domain</one> is typically involved in ... ? <one>Ubiquitination</one>. 
+- Was ist <one>Endocytose</one>? Die Aufnahme von Flüssigkeit sowie großen und kleineren Molekülen in eine eukaryotische Zelle (nicht bei Prokaryoten)
+- In general: <one>activation of p53</one> has which two different possible <two>cellular outcomes</two>? (1) <one>cell-cycle arrest</one> (2) <one>apoptosis</one>
+- <one>Cell surfaces</one> in general tend to be <two>rather positively</two> or <two>rather negatively</two> charged? <one>Cell surfaces</one> tend to be <two>negatively charged</two>.
+- Die <one>t-SNARES</one>: kann man sich das merken, was die auf zellulärer Ebene machen? Ja, über das <one>t ... tethering factor</one> mnemonic.
+- Welche <one>drei Autophagen-Mechanismen</one> existieren? (1) <one>crinophagy</one> (2) <one>macroautophagy</one> (3) <one>microautophagy</one>
+- What is <one>the most important parameter</one> <two>in animal cell culture</two>? The <one>concentration of cells</one>.
+- The <one>human mtDNA</one> codes for <two>n transfer RNAs</two>? <one>22</one>. URL: https://pubmed.ncbi.nlm.nih.gov/15983868/
+- Name the <one>two proteins</one> that control the transition from G2 to M-phase. A: (1) <one>cdk1</one> (2) <one>cyclin B</one>
+- In der <one>Autophagie</one> bei der Zellbiologie: was heisst <two>PAS</two>? <two>Phagosome assembly site</two>.
+- <one>FSH</one> in humans means what? <one>Follicle-stimulating hormones</one>.
+- In cellbiology: name a classic model of <one>motor functions</one>. A: <one>Skin pigmentation in fish</one>.
+- Andere Bezeichnung für <one>transversale Bewegung</one> eines Proteins in einer Zellmembran? <one>Flip-flop</one>.
+- Name two <one>microtubule motors</one>. A: (1) <one>Kinesin</one> (2) <one>Dynein</one>
+- <one>When</one> was the <two>first human neocentromere</two> discovered? In the year <one>1993</one>.
+- What does it tell us if a protein has the designation <one>p38</one> or <one>p53</one> or <one>p88</one>? This refers to the relative molecule mass of 38K or 53K or 88K.
+- <one>Where in a cell</one> can the <two>Ras protein</two> be found? <one>Ras</one> is usually attached to the cell membrane owing to its <two>prenylation</two> and <two>palmitoylation modification</two>.
+- Bei den <one>pH Werten in biologischen Systemen</one>: <two>wie liegt die phosphoryl head group in Membranen vor</two>? <one>Negativ geladen</one>, als <two>Phosphatidate</two>.
+- <one>Plectin</one> is a <two>cytoskeletal linker protein</two>. <three>What size does it have</three>? Plectin is very large, with a size of over <one>500 kDa</one>.
+- What is the <one>Interphase</one>? All but Mitosis; so we have G1, S and G2.
+- What is <one>Hemifusion</one> in cell biology? During membrane fusion, the outer leaflets of the two membranes merge first, whereas the distal membrane leaflets remain separate until the opening of a fusion pore. This intermediate stage is called a hemifusion.
+- The <one>Shibire mutation</one> <two>in Drosophila</two> led to <three>the discovery of which cellular protein</three>? <one>Dynamin</one>. URL: https://pubmed.ncbi.nlm.nih.gov/1674590/
+- In der Zelle: <one>welche Aufgabe</one> hat <two>Stathmin</two>? Stathmin reguliert <one>microtubule dynamics</one>.
+- Wofür steht die Abkürzung bei der <one>MAP Kinase</one>? <one>Mitogen-activated protein kinase</one>. URL: https://de.wikipedia.org/wiki/MAP-Kinase-Weg
+- What is <one>crinophagy</one>? The direct fusion of lysosomes with secretory vesicles.
+- Anteil, in Prozent, von <one>Actin</one> an den Gesamtproteinen in einer eukaryotischen Zelle (<two>von-bis</two>)? Etwa <one>10-20%</one>.
+- Name <one>a drug</one> that can be used to <two>inhibit the function of lysosomes</two>. A: <one>Chloroquin</one>.
+- Andere Bezeichnung für <one>Aktin</one>? <one>Mikrofilamente</one>. Sie haben ja nur einen Durchmesser von etwa 6nm.
+- What does the abbreviation <one>Gamma-TuRC</one> stand for? <one>Gamma-tubulin ring complex</one>.
+- Aus Sicht der Zellbiologie: was passiert wenn das Gen <one>N-Acetylglucosamin-Phosphotransferase</one> ausfällt? Essenzielle Enzyme, wie zum Beispiel Hydrolasen, können nicht mehr ins Lysosom gelangen.
+- Do <one>phospholipids</one> <two>spontaneously form bilayers</two>? Yes, under the appropriate conditions they will.
+- Give another name for the <one>cyclin-dependent kinase inhibitor 1</one>. A: <one>p21</one>.
+- What is a <one>Rab cascade</one> in cell biology? This is the ordered recruitment of sequentially active Rab proteins.
+- Das <one>wichtigste transmembranale Protein in Mitochondrien</one> ist ... ? <one>Porin</one>.
+- <one>Which chaperone</one> is important for <two>posttranslation translocation</two>? <one>BiP</one>.
+- How do we call <one>the interior of the nucleus</one>, for the most part? <one>Nucleoplasm</one>. URL: https://en.wikipedia.org/wiki/Nucleoplasm
+- Was bedeutet <one>Eutelie</one>? <one>Zellkonstanz</one>.
+- What is <one>exocytosis</one>? <one>Exocytosis</one> is an energy-using process by which a cell directs the contents of secretory vesicles into its extracellular space.
+- Wie können wir den Zerfall der Mikrotubuli bewirken? Durch Einsatz von <one>Colchicin</one>.
+- Give another name for the <one>cyclins</one>. A: <one>Cdk regulators</one>.
+- Nenne <one>eine Tiergruppe</one> die <two>keine Intermediärfilamente</two> aufweist. A: <one>Arthropoden</one> haben keine Intermediärfilamente; Pflanzen übrigens auch nicht. URL: http://www.bionity.com/de/lexikon/Intermedi%C3%A4rfilamente.html
+- What are <one>Biologics</one>? Genetically engineered proteins derived from human genes, designed to inhibit specific components of the immune system, especially those that play a role in inflammation.
+- Wie gross kann eine <one>aerobe Zelle</one> werden? So gross das sie gerade noch Sauerstoff aufnehmen und verteilen kann.
+- In cell biology: what is meant with the expression <one>intrinsic fluorescence</one>? When some proteins or small molecules, in a given cell, are <one>naturally fluorescent</one>.
+- What is the protein <one>SOS</one> (<two>son of sevenless</two>) doing? It <one>exchanges GDP → GTP</one>. URL: https://en.wikipedia.org/wiki/Son_of_Sevenless
+- On the outside, the <one>nuclear pore complex</one> contains <two>cytoplasmic filaments</two>. Name two cellular functions that these filaments participate in. A: (1) protein transport (2) <one>mRNA export</one>
+- Wie nennt man <one>die Verschmelzung verschiedenartiger Genome in einer Zelle</one>? <one>Intertaxonische Kombination</one>. (Solche Organismen sind aus genetischer Sicht Chimären).
+- What is <one>autophagy</one>? Degradation of intracellular substrates.
+- <one>Welches Protein</one> kann <two>die cytosolische Menge an cytochrom c</two> <three>messen</three>? <one>Apaf-1</one>.
+- Nenne <one>zwei Beispiele</one> für <two>amphiphile Moleküle</two>. A: (1) <one>Phospholipide</one> (2) <one>Lecithine</one>
+- Für den <one>Zellkern-Export bestimmte Proteine</one> haben oft was? <one>Leucin-reiche Sequenzen</one>.
+- <one>Why</one> do we use a <two>Langmuir-Blodgett trough</two> in a laboratory? We can use it to compress monolayers of molecules on the surface of a given subphase, and then measures surface phenomena due to this compression.
+- <one>Zellen</one> besitzen <two>welche drei Typen</two> von Zell-Zell Verbindungen? (1) tight junctions (2) adhering junctions (3) gap junctions (Merkslogan: T,A,G junctions)
+- In cell biology: what is the main statement central to the <one>cisternal maturation hypothesis</one>? <one>Endoplasmic reticulum ER-derived membranes</one> nucleate new Golgi cisternae.
+- <one>Theodor Engelmann</one> <two>used which organism</two> in his photosynthesis experiment? <one>Cladophora engelmann</one>.
+- <one>When</one> exactly is the <two>sister-chromatid cohesin</two> destroyed? At the start of the <one>Anaphase</one>.
+- Wie <one>nennen</one> wir die charakteristische <two>innere</two> Anordnung der Geißeln der Eukaryoten? <one>9x2+2</one>.
+- What is a <one>chromocyte</one>? Any cell that contains a pigment. URL: https://en.wiktionary.org/wiki/chromocyte
+- Durch <one>Kernporen</one> können <two>kleinere Proteine bis zu einer Grösse von n kDa</two> passiv eindringen? Bis zu <one>60 kDa</one>.
+- The activity of the <one>protein kinase A</one> depends on ... ? The <one>cellular levels of cyclic AMP</one> (<two>cAMP</two>).
+- <one>Wie</one> wird der Export eines Proteins aus dem Nucleus gesteuert? Über <one>NES</one>: <two>Nuclear Export Signal</two>.
+- What is <one>the job</one> of the <two>lipoprotein particles</two>? Carry lipids via the bloodstream to other parts of the body.
+- <one>Desmosomes</one> are <two>anchorage sites</two> for ...? <one>Intermediate filaments</one>.
+- In the cell cycle: what means <one>MUGs</one>? <one>Mitosis</one> with <two>unreplicated genomes</two>.
+- Name <one>an adaptor protein</one> for <two>Ras-Proteins</two>. A: <one>Grb2</one>.
+- Name <one>four structural components</one> of a mitochondrium. A: (1) Outer Membrane (2) <one>Matrix</one> (3) Inner Membrane (4) Intermembrane space
+- Was kann das Protein <one>BAX</one> bewirken? Die <one>Apoptose einer Zelle</one>. URL: https://de.wikipedia.org/wiki/Bax_(Protein)
+- <one>Andere Bezeichnung</one> für <two>anaphase-promoting complex</two>? The <one>cyclosome</one> (Merkhilfe: APC/C heisst der Komplex eigentlich, das 2. C steht eben für <two>Cyclosome</two>).
+- Warum der Name <one>P-Selectine</one>? <one>Platelets</one> (<two>Plättchen</two>).
+- In <one>Tunel Labeling</one>: <two>which antibodies are used</two>? <one>Br(d)U specific antibodies</one>.
+- <one>Where exactly</one> do we find the <two>SECIS element</two>? The <one>SECIS element</one> can be found in the <two>3' UTR</two>.
+- <one>Muskelfasern</one> zeigen im Elektronenmikroskop eine <two>charakteristische Querstreifung</two>, die wodurch verursacht wird? Diese Querstreifung wird durch die <one>Sarkomere</one> verursacht.
+- <one>cGMP</one> <two>can bind to which protein kinase</two>? To the <one>protein kinase G</one>.
+- <one>Menschliche Zellkerne</one> besitzen im Durchschnitt <two>n Kernporen</two> / Zellkern? <one>3000</one>.
+- Do <one>plants</one> use <two>cAMP for signalling</two>? <one>No</one>.
+- In <one>induction of autophagy</one>: <two>who normally inhibits Atg1</two>? The <one>TOR kinase</one>.
+- Give another expression for the phenomenon of two, or more, organelles coming into close apposition. A: <one>Inter-organellar membrane contacts</one>.
+- Nenne ein Zellorganell das <one>Cardiolipin</one> enthält. A: Das Mitochondrium und zwar die innere Membran des Mitochondriums.
+- Can the <one>nuclear lamins</one> be <two>phosphorylated</two>? Most likely, because they can definitely be <one>dephosphorylated</one>.
+- Wie schnell sind <one>G-Proteine</one>, allgemein? Etwa 3 Umwandlungen / <one>Minute</one>.
+- <one>Woran</one> binden die <two>Rab-Domänen</two> der Rab-Proteine? Sie binden an Tethering-Faktoren. Rab-Proteine befinden sich während und nach der Fusion in einem inaktiven, zytosolischen Zustand und stehen so für neue Tethering-Ereignisse zur Verfügung. Der Tethering-Faktor ist auf der Zielmembran.
+- Why is the <one>histone fold</one> so important? So that the <one>histone octamer</one> can form.
+- <one>G-Proteine</one> besitzen was für eine Aktivität? Eine <one>GTPase Aktivität</one>. URL: https://de.wikipedia.org/wiki/G-Proteine
+- What does the <one>signal hypothesis</one> state? The site of synthesis of a protein was determined by the sequence of amino acids in the N-terminal portaion of the polypeptide.
+- Wieso benötigt eine Zelle <one>Ribose-5-phosphat</one>? Zur <one>Synthese</one> von <two>RNA</two> und <two>DNA</two>.
+- Wie heißt das <one>endoplasmatische Retikulum</one> auf Englisch? <one>Endoplasmic reticulum</one>. URL: https://en.wikipedia.org/wiki/Endoplasmic_reticulum
+- How is the inner part of a <one>plasmodesma</one> called? <one>Desmotubule</one>.
+- In cellbiology, related to G proteins: what are the <one>RGS</one>? <one>RGS</one> are <two>Regulators of G protein signaling</two>. They can activate GTPases for heterotrimeric G-protein alpha-subunits.
+- Nenne <one>eine sterolähnliche Verbindung in der Zellmembran</one> von <i>Pseudomonas syringae</i>. A: <one>Hopanoide</one>.
+- Die <one>ATPase</one> besitzt einen <two>F0 Teil</two> und einen <two>F1 Teil</two>. <three>Welcher dieser beiden Teile ist der katalytisch wirkende Teil</three>? <one>F1</one>.
+- The <one>lipid molecules in a cell membrane's continuous double layer</one> are <two>about n nm thick</two>? About <one>5 nm thick</one>.
+- In der Zellbiologie: was kann Dank <one>GFP-tagging</one> zellulär erreicht werden? Wir können so zum Beispiel die Kompartimentierung von Proteinen in der Zelle untersuchen.
+- <one>Wann</one> wurde die <two>RNA-World Hypothesis</two> vorgestellt? Im Jahre <one>1986</one>.
+- Name <one>the three principal organelles</one> of the <two>secretory pathway</two>. A: (1) The <one>ER</one> (2) The <one>Golgi apparatus</one> (3) The <one>plasma membrane</one>
+- What is <one>the total mass</one> of the <two>ATP synthase</two>, <three>in Daltons</three>? <one>600.000 Daltons</one>.
+- Can <one>gap junctions</one> be found in <three>erythrocytes</three>? No. URL: https://en.wikipedia.org/wiki/Gap_junction
+- Name <one>the three principal organelles of the secretory pathway</one>. A: (1) the <one>endoplasmic reticulum</one> (2) the <one>Golgi apparatus</one> (3) the <one>plasma membrane</one>
+- Aus welchen <one>Domänen</one> besteht ein <two>Motorprotein</two>? Aus einer <one>Kopfdomäne</one> sowie einer <one>Schwanzdomäne</one>.
+- Nenne <one>zwei Typen membranständiger Multiproteinkomplexe</one>, die am <two>Transport mitochondrialer Proteine</two> beteiligt sind. A: (1) <one>TIM</one> (2) <one>TOM</one>
+- <one>When</one> is a <two>Rab Protein</two> active? When it has bound <one>GTP</one>.
+- What are <one>sad cells</one>? <one>Cells in culture that die after some weeks</one>.
+- In der Zellbiologie: was ist eine <one>Signalsequenz</one>? Eine <one>Signalsequenz</one> ist eine Peptidsequenz mit der Information wie und wohin ein Protein innerhalb einer Zelle transportiert werden soll.
+- The <one>outer nuclear membrane</one> is continuous with ... ? the <one>endoplasmic reticulum</one>.
+- Define the term <one>cytosol</one>. A: The <one>cytosol</one> is the organelle-free part of the cytoplasm.
+- Was heisst <one>Tom complex</one>? <one>Translocase of the outer mitochondrial membrane</one>.
+- Was ist die Rolle des <one>Pyruvat Dehydrogenase Complex</one> (<one>PDC</one>) in der Zelle? Dieser mitochondriale Porenkomplex <one>importiert Acetyl-CoA</one>.
+- In the cytoplasm, hydrolysis of ... to ... causes <one>dissociation of the export complex</one>. A: "Ran-GTP" -> <one>Ran-GDP</one>.
+- In der Biologie, wo finden wir <one>rafts</one>? In der <one>Membran</one> (es sind <two>Membranproteine</two>).
+- Was sind die <one>Elektronenüberträger</one> innerhalb der Zelle? NAD/H + NADP/H.
+- Ein <one>Lariat</one> hat was für eine Struktur genau? Zirkuläre RNA mit <one>3' OH-Gruppe-</one>.
+- <one>Activated Raf</one> ultimately activates ... ? <one>MAP Kinase</one>.
+- Unterschied zwischen den <one>saturated fatty acids</one> und <one>unsaturated fatty acids</one>? Die saturated fatty acids haben C-C Bindungen die nur Einzelbindungen sind. Die unsaturated fatty acids hingegen haben C=C Bindungen, also Doppelbindungen.
+- <one>Phospholipase C</one> <two>can activate which pathway</two>? The <one>inositol 1,4,5-trisphosphate pathway</one>.
+- The interiors of cellular compartments communicate with one another via ... ? Via <one>transport vesicles</one>.
+- Was wird durch <one>Pinocytose</one> aufgenommen? <one>Flüssigkeiten</one>.
+- In cell biology: what is a <one>retromer</one>? A complex of proteins that has been shown to be important in recycling transmembrane receptors from the endosomes to the trans-Golgi network.
+- <one>When</one> was the structure of the <two>nucleosome core particle</two> solved? In the year <one>1997</one>.
+- The <one>Coatomer</one> consists of <two>how many different coat ("COP")-proteins</two>? <one>7</one>. URL: https://en.wikipedia.org/wiki/Coatomer
+- Der Farbstoff <one>Hämatoxylin</one> färbt was genau innerhalb einer Zelle an? Den <one>Zellkern</one>.
+- There is the <one>Ras superfamily</one>. What does <two>Rab</two> stand for? <one>Ras-like in Brain</one>. URL: https://en.wikipedia.org/wiki/Rab_(G-protein)
+- Nenne einen sehr wichtigen <one>cell survival factor</one>. A: Der <one>Transkriptionsfaktor NF-Kappa Beta</one>. Er aktiviert Gene die für <two>cell-survival Proteine</two> kodieren.
+- Give an example for <one>a monomeric GTPase</one>. A: The <one>Ras-proteins</one>. URL: https://en.wikipedia.org/wiki/Ras_GTPase
+- Give another name for the <one>G0-phase</one>. A: <one>Resting state</one>.
+- What is <one>Transcytosis</one>? Transcytosis is the process by which various macromolecules are transported across / through the interior of a cell.
+- What does it mean when we say that <one>the subunits of actin filaments are asymmetrical</one>? These subunits bind to one another head-to-tail, so that they all point in one direction.
+- <one>Durchmesser einer Kernpore</one>, <two>in nm</two>? Etwa <one>120 nm</one>.
+- Give another name for <one>photoreceptors</one>. A: <one>Molecular light switches</one>.
+- Was bedeutet der Name bei der <one>I-cell disease</one>? <one>Inclusion-cell disease</one>.
+- What is the <one>transitional ER</one>? These are areas of smooth ER that bud off for transport to the Golgi apparatus.
+- Andere Bezeichnung für den <one>Golgi-Komplex</one>. A: <one>Sortierungszentrum</one>.
+- How do we call the vesicles derived from the <one>endoplasmic reticulum</one>? <one>Microsomes</one>. URL: https://en.wikipedia.org/wiki/Microsome
+- Name <one>an important, extracellular matrix protein</one>. A: <one>Fibronectin</one>.
+- Which <one>three components</one> can we find in the ABC transport system? (1) substrate-binding protein (2) membrance-integrated transporter (3) ATP-hydrolyzing protein
+- Name a common (functional) feature of <one>karyopherins</one>. A: <one>Karyopherins</one> interact with <two>Ran proteins</two>.
+- Was sind <one>MDCK Zellen</one>? <one>Madin-Darby canine kidney cells</one>.
+- Was ist ein <one>RNA-Thermosensor</one>? Dies bezeichnet eine RNA, die mittels Veränderung ihrer Sekundärstruktur Temperatur "messen" kann.
+- <one>Caspases</one> cleave the target proteins at? At a specific <one>aspartic acid</one>. URL: https://en.wikipedia.org/wiki/Caspase
+- Wie werden die <one>drei Stapel</one> im Golgi-Apparat genannt? (1) <one>cis</one> (2) <one>medial</one> (3) <one>trans</one>
+- Das Medikament <one>Eribulin</one> bindet woran? An das <one>+Ende wachsender Mikrotubuli</one>.
+- Why is <one>PAS</one> (<two>pre-autophagosomal structure</two>) so important? Most proteins involved in autophagosom formation localize to the PAS at some stage.
+- <one>Diacylglycerol</one> wird als Ausgangssubstanz für welches Phospholipid benötigt? <one>Phosphatidylcholin</one>. URL: https://de.wikipedia.org/wiki/Lecithine
+- When an <one>early endosome</one> becomes a <two>late endosome</two>, aside from morphology, what else may change that is rather important? It will become <one>increasingly acidic</one>.
+- Do <one>growth factors</one> also belong to the group of <two>cytokines</two>? Yes. URL: https://en.wikipedia.org/wiki/Growth_factor
+- Um auf ein <one>Hormon</one> reagieren zu können, brauchen die Zellen ... ? einen <one>Rezeptor</one>.
+- Lysosomaler Enzym-Schutz? Zum einen pH-Optimum von 5-6; zum anderen ein <one>Oligosaccharidpanzer</one>, also <two>hochglykosyliert</two> als Schutz vor Autolyse durch lysosomale Proteasen.
+- How do we call the <one>heterotrimeric G-protein of Rhodopsin</one>? <one>Transducin</one>. URL: https://en.wikipedia.org/wiki/Transducin
+- <one>pH Wert</one> in einem <two>Lysosome</two>? <one>5</one>.
+- Nenne einen Marker in <one>smooth muscle cells</one>. A: <one>Calponin</one>.
+- <one>How</one> is the pH of Lysosomes maintained? By the <one>vacuolar adenosine triphosphatase proton pump</one>.
+- <one>Welches Signalpeptid</one> wird nicht abgespalten? Das <one>Kernlokalisationssignal</one>.
+- Was ist mit dem Begriff <one>primäre Endocytobiose</one> gemeint? Das Aufnehmen eines Prokaryoten und dessen Reduktion auf die Stufe eines Organells im Laufe der Evolution. Wichtig bei der Mitochondrien und Chloroplasten-"Entstehung".
+- <one>Calmodulin</one> besitzt <two>n Ca²⁺ binding sites</two>? <one>4</one>. URL: https://en.wikipedia.org/wiki/Calmodulin
+- What is <one>Pyknosis</one>? This is <one>the irreversible condensation of chromatin in the nucleus of a cell undergoing necrosis or apoptosis</one>.
+- In cell biology: what is the <one>kiss of death</one>? <one>The addition of Ubuiqitin to proteins</one>. This addition often commits the labelled protein to degradation in the 26-S proteasome.
+- <one>Neu synthetisierte Proteine</one> müssen <two>korrekt gefaltet werden</two>. Die dazu <three>notwendigen Hilfsproteine</three> heißen ... ? <one>Chaperone</one>. URL: https://de.wikipedia.org/wiki/Chaperone
+- Welche Aufgabe hat der <one>ComEC Complex</one>? Der ComEC Komplex macht einen Channel (wichtig für die Kompetenz).
+- Andere Bezeichnung für <one>Zellkörper</one>? <one>Perikaryon</one>.
+- <one>Fibrinogen</one> kann vor allem an die Rezeptoren welcher Zellen binden? An die <one>Thrombozyten</one>.
+- Was produziert die <one>Phosphodiesterase</one>? <one>AMP</one>.
+- In der Zellbiologie: was genau heisst <one>Caspase</one>? <one>Cysteinyl-aspartat-spezifische Proteinase</one>.
+- In cell biology: what does <one>FAOS</one> stand for? <one>Fluorescence-assisted organelle sorting</one>.
+- <one>Microfilaments</one> are formed by ... ? <one>Actin</one>.
+- <one>When</one> was the <two>nucleosome</two> discovered? In the year <one>1974</one>.
+- Nenne eine besondere Domäne am <one>EGF-Rezeptor</one>. A: Die <one>Dimerisierungsdomäne</one>.
+- Was heisst <one>iPS</one>? <one>Induzierte, pluripotente Stammzellen</one>.
+- Name a complex similar to the <one>Gamma-TuRC complex</one>. A: The <one>ARP complex</one>.
+- Give another name for the term <one>autophagy</one>. A: <one>Organelle turnover</one>. URL: https://en.wikipedia.org/wiki/Organelle
+- Was ist ein <one>Gewebe</one>? Dies ist <one>ein Verbund von Zellen mit gemeinsamer Funktion</one>.
+- Nenne ein zelluläres Ereignis, das durch <one>exogene Noxen</one> ausgelöst werden kann. A: Die <one>Nekrose</one>.
+- What is the job of the <one>satellite muscle cells</one>? They repair injured muscle cells. Satellite cells can self-renew and proliferate, thus providing new myogenic cells.
+- Was genau ist die <one>Matrix</one> der Mitochondrien? Das ist genau <one>der innerste Teil der Mitochondrien</one>.
+- <one>Below a certain temperature</one>, lipids are in ... which form? They tend to be in a <one>paracrystalline</one> form.
+- <one>Wo</one> findet man die <two>tSNAREs</two>? Auf der <one>Zielorganelle</one>.
+- <one>G-Proteine</one> bestehen aus drei Untereinheiten. Welche davon bindet GTP? Die <one>alpha-Untereinheit</one> bindet (und hydrolysiert) GTP.
+- Aufgabe der <one>Calpaine</one>? <one>Calpaine</one> <two>bauen Muskeleiweiß ab</two>. URL: https://en.wikipedia.org/wiki/Calpain
+- The ability of <one>importins</one> and <one>exportins</one> to transport their cargo is regulated by ...? <one>Ran</one>, a small Ras-related GTPase.
+- What is <one>the central component of the translocon</one>? The <one>Sec61 complex</one>.
+- <one>How</one> is the <two>Ras signal-transduction pathway</two> activated? When e. g. EGF binds to a receptor.
+- Give another, prettier name for <one>pigments</one>. A: <one>Rainbow catchers</one>.
+- <one>Where</one> does the <two>signal peptidase</two> reside? In the <one>ER membrane</one>.
+- <one>Griseofulvin</one> wirkt wie? Griseofulvin hemmt den Spindelapparat der Zelle, indem es an Tubulin bindet.
+- Wie werden die <one>Intermediärfilamente in Nervenzellen</one> genannt? <one>Neurofilamente</one>. URL: https://de.wikipedia.org/wiki/Intermediärfilamente#Typen
+- The <one>Nuclear pore complexes</one> consist of about <two>n different proteins</two>? About <one>30</one>.
+- Wie werden die <one>Intermediärfilamente im Zellkern</one> genannt? <one>Lamina</one>.
+- Nenne die zwei <one>Ionenkanaltypen</one>. A: (1) <one>spannungs-gesteuerte Ionenkanäle</one> (2) <one>liganden-gesteuerte Ionenkanäle</one>
+- The <one>SCF complex</one> promotes ...? <one>Degradation of CKIs</one>.
+- <one>Integrins</one> have how many <two>switchable conformations</two>? <one>2</one> (active/inactive conformation).
+- Warum haben <one>Integrine</one> ihren Namen? Sie haben die Fähigkeit, extrinsische Signale in Veränderungen des Cytoskeletts der betreffenden Zelle zu "integrieren".
+- What are <one>ameloblasts</one>? These are cells that are important for tooth development. They <one>deposit tooth enamel</one>.
+- Wo befinden sich <one>vSNARE Proteine</one>? Sie befinden sich <one>in der Vesikelmembran</one>.
+- <one>Diffusion</one> erfolgt nach <two>welchem Gesetz</two>? Nach dem <one>Fickschen Diffusionsgesetz</one>. URL: https://de.wikipedia.org/wiki/Diffusion#Erstes_Ficksches_Gesetz
+- The <one>ER</one> cycles between ...? The <one>ER membrane</one> and the <one>cytosol</one>.
+- What is the job of <one>Bacteriorhodopsin</one>? This protein functions as <one>a light-activated H+ pump</one> that transfers H+ out of the archaeal cell.
+- Name <one>two things</one> that <two>mature mammalian red blood cells</two> lack. A: (1) <one>nucleus</one> (2) <one>cytoplasmic organelles</one>
+- In cell biology: what does "autophagy" ensure or a given normal cell? <one>Autophagy</one> ensures the synthesis, degradation and recycling of cellular components.
+- The main reaction types of <one>cell synthesis</one> are ... ? <one>Polymerization Reactions</one>.
+- Wieso werden <one>Sterole</one> in die Zellmembran eingebettet und welches Dilemma haben manche Prokaryoten hier? Um sie zu verstärken. Manche Prokaryoten können diese Sterole nicht selbst synthetisieren und nehmen sie aus der Umgebung auf.
+- What is <one>Allotransplantation</one>? When the donor organ comes from a <one>closely related species</one>.
+- Was ist die sogenannte <one>korpuskuläre Absorption</one>? (1) Phagocytose (2) Pinocytose (3) <one>Endocytose</one>
+- What are <one>spheroid cells</one>? This is <one>a 3D cell culture method</one> where a small aggregate of cells grows free of foreign materials.
+- Aufgabe der <one>SUN</one> und <one>KASH</one> Proteine? Sie verbinden den Nucleus und das Cytoplasma durch die Zellkern-Membran.
+- What are <one>primary cultures</one>? These are <one>cultures prepared directly from the tissues of an organism</one>.
+- Wie wird <one>die Länge der Aktinfilamente</one> <two>reguliert</two>? Mit Hilfe der <one>Motorproteine</one>. Diese bewegen sich entlang der Filamente und kürzen sie, wenn sie zu lang werden.
+- Was sind <one>Kinozilien</one>? Das sind <one>Wimpern</one> beim, zum Beispiel, Wimpertierchen.
+- <one>Wann</one> sind Chromosomen <two>unsichtbar</two>? In der <one>Interphase</one>.
+- What is meant with the term <one>Autophagy</one>? <one>Autophagy</one> is a cellular, catabolic mechanism that involves cell degradation of unnecessary cellular components through the actions of lysosomes.
+- <one>Durchmesser eines Nucleosoms</one>? <one>11 nm</one>.
+- <one>Karyopherins</one> are <two>nuclear transport receptors</two> that bind to ... ? <one>Nups</one>.
+- What is the <one>rate-limiting step</one> in the <two>formation of actin filaments</two>? <one>Nucleation</one>.
+- Chemischer Name für <one>Caffeine</one>? <one>1,3,7-trimethylxanthine</one>.
+- <one>Welcher Wachstumsfaktor</one> spielt bei <two>Blutgerinnung</two> und <two>Wundheilung</two> eine Rolle? <one>PDGF</one>. URL: https://en.wikipedia.org/wiki/Platelet-derived_growth_factor
+- What is <one>the main signal</one> for protein delivery into lysosomes? <one>M6P</one> (<two>Mannose 6-phosphate</two>).
+- In cell biology: what do we mean with the term <one>free ribosome</one>? Ribosomes that are not attached to the RER.
+- In cellbiology: what are the <one>CAKs</one>? <one>Cdk-activating kinases</one>.
+- Das Enzym <one>Thymidylate Synthetase</one> benötigt eine Methyl-Gruppe. Woher stammt diese? Von <one>Tetrahydrofolate</one>.
+- Give another name for <one>cytokinesis</one>. A: <one>Cytoplasmic division</one>.
+- <one>Dystrophin</one> bindet ... an die Zellmembran von Muskelzellen. A: <one>Actinfilamente</one>.
+- Bei <one>G-Proteinen</one>: ist der Komplex aus GDP + G(alpha,beta,gamma) aktiv? Nein, er ist <one>inaktiv</one>.
+- What does <one>pinocytosis</one> literally mean? <one>Cellular drinking</one>.
+- Was für ein Typ sind <one>RAB-Proteine</one>? <one>Kleine GTPasen</one>.
+- <one>Dendritische Zellen</one> - was heisst <two>dendritus</two>? <one>Verzweigt</one>.
+- Nenne eine Möglichkeit wie man den Zeitpunkt der <one>S-Phase</one> experimentell bestimmen kann. A: Durch Verwendung von <one>Bromodeoxyuridin</one>.
+- <one>Plectin</one> can bind to ... ? <one>Desmin</one>.
+- <one>Macroautophagy</one> creates what? An <one>autophagic vacuole</one>.
+- Is <one>cell fusion</one> important in <two>practical cellbiology</two>? Give an example. A: Yes, it can be <one>used to produce monoclonal antibodies</one>.
+- Andere Bezeichnung für die <one>Vakuolenmembran</one>? <one>Tonoplast</one>. URL: https://de.wikipedia.org/wiki/Tonoplast
+- <one>When</one> are compartments said to be <two>topologically equivalent</two>? If they can communicate with one another in the sense that molecules can get from one to the other without having to cross a membrane.
+- <one>Formine</one> können die <two>Polymerisation von</two> ... induzieren. A: <one>Aktin</one>.
+- How do we call the clear gel that is part of <one>the matrix surrounding animal cells</one> in a tissue? The <one>extracellular fluid</one> (<one>ECF</one>).
+- What is the <one>opposite</one> of the secretory pathway? The <one>endocytic pathway</one>.
+- Give another name for <one>Ubiquitin E1</one>. A: <one>Ubiquitin-activating enzyme</one>.
+- Wie weit sind <one>die Membranen des Zellkerns</one> voneinander entfernt (von, bis)? <one>10-50 nm</one>.
+- In cellbiology: what is a <one>Shmoo</one>? A shmoo is a budding yeast responding to a pheromone from the opposite mating type (either a or alpha) - Yeast-Cells that undergo mating present this particular structure, and look like such a "shmoo"- thus, the whole process is known as "shmooing".
+- The only <one>direct intercellular junctions</one> that exist in plants are ... ? <one>Plasmodesmata</one>.
+- <one>Integrins</one> can, on the outside of a cell, bind to ... ? <one>Fibronectin</one>.
+- Was ist die Grundlage eines <one>Riboswitch</one>? Wirkt wie ein <one>Schalter</one> - einmal kann er abgelesen werden, ein anderes mal nicht.
+- In der Zellbiologie: was meinen wir mit dem Begriff <one>Heterophagie</one>? Dies ist <one>das Verdauen zellfremder Substanzen</one>.
+- What was the first <one>membrane transport protein</one> whose structure was determined? <one>Bacteriorhodopsin</one>.
+- In der Zellbiologie gibt es <one>COPII</one>. Dieses Protein ist wichtig beim Protein-Transport von RER zum Golgi Apparatus. Wofür steht das Wort COPII? <one>Coat Protein Complex II</one>.
+- Der <one>Austausch von Ionen im ladungsneutralen Gegenstrom</one> heißt ... ? <one>Antiport</one>.
+- Wo finden wir die <one>Cathepsine</one>? Im <one>Lysosom</one>.
+- Warum das <three>g</three> in <one>G1-Phase</one>? <one>g</one> steht hier für <one>gap</one>.
+- In cell biology: whats means <one>dynamic instability</one>? This refers to the coexistence of assembly and disassembly at the + end of a microtubule.
+- Der Durchmesser eines <one>Histon-Oktamers</one> beträgt ... ? <one>11 nm</one>.
+- Nenne eine Möglichkeit wie die Zelle die <one>GTP-Hydrolyse</one> von GPCRs beschleunigen kann. A: Sie kann <one>GAPs</one> (<two>GTPase-aktivierende-Proteine</two>) verwenden.
+- In der Zellbiologie: was heisst <one>ERAD</one>? <one>ER-associated degradation</one>. URL: https://en.wikipedia.org/wiki/Endoplasmic-reticulum-associated_protein_degradation
+- How do we call an <one>inactive caspase</one>? <one>Procaspase</one>.
+- In der Zellbiologie, gib ein anderes Wort an für das <one>KDEL Signal</one>, auf Englisch. A: <one>ER retention sequence</one>.
+- Warum benötigt eine Zelle die <one>Intermediärfilamente</one>? Diese sind die stabilsten Bestandteile des Zytoskeletts. Bei ihnen steht die <one>Stützfunktion</one> im Vordergrund.
+- <one>Prenylation</one> is what? The linkage of C15/C20 units to <one>cysteine side chains</one>.
+- Auf Ebene der Zelle: was bewirkt eine aktivierte <one>Protein-Kinase A</one>? A: Dieses Enzym katalysiert die Phosphorylierung anderer Proteine, was zu einer zellulären Antwort führt (i. e. bei einer vorhergegangengen Aktivierung über einen G-Protein gekoppelten Rezeptor).
+- Name a dangerous but very effective way to stop all cell division. A: <one>High exposure to x-rays</one>.
+- Ist <one>Importin Alpha</one> oder <one>Importin Beta</one> wichtiger? <one>Importin Alpha</one>, denn es bindet an das für den Zellkern bestimmte Protein.
+- Angenommen wir möchten das glatte ER in der Zelle massiv proliferieren lassen. Was könnten wir tun? Wir könnten <one>Barbiturate</one> verwenden.
+- Das <one>BiP Protein</one> ähnelt welch anderem Protein? <one>Hsp70</one>.
+- Innerhalb einer Zelle schaffen Membranen ...? <one>Abgegrenzte Reaktionsräume</one>.
+- What is <one>the most remarkable ER specialization</one>? The <one>rough ER</one>.
+- Name a way how to detect cells in the S-phase. A: For instance, via <one>BrdU Incorporation</one>.
+- Was ist zum <one>Zellkern von Osteoklasten</one> zu sagen? Diese Zellen sind <one>mehrkernig</one>.
+- How do we call a fused t-SNARE and v-SNARE? <one>trans-SNARE complex</one>.
+- What is the main minus-end directed <one>motor-protein</one> on microtubules? <one>Dynein</one>.
+- What is the <one>I-cell disease</one>? Material accumulates in the lysosomes because of the absence of hydrolytic enzymes due to the enzyme phosphotransferase unable to add phosphate groups to mannose in the Golgi complex.
+- Name 3 important jobs for the ER (Endoplasmatic Reticulum). A: (1) lipid-biosynthesis (2) protein biosynthesis (3) intracellular Ca 2+ store
+- Proteine die in die Mitochondrien importiert werden sollen, haben was für eine leader sequence? Am N-Terminus 20 oder mehr Aminosäuren.
+- Wie funktioniert der Import von Proteinen in das Mitochondrium? Mitochondrien haben Rezeptoren, die bestimmte Signalsequenzen binden können.
+- Gib ein Beispiel für eine Serin/Threoninkinase. A: Proteinkinase A.
+- The <one>cytosylic pH</one> <two>is at ...</two>? At about a value of <one>7.2</one>. []
+- Nenne <one>zwei verschiedene Hemmstoffe</one> der <two>cAMP-Phosphodiesterase</two>. A: (1) <one>Coffein</one> (2) <one>Theophyllin</one> []
+- Das <one>clathrin triskelion</one> <two>besteht aus ... </two>? Es ist ein <one>Hexamer</one>, bestehend aus <two>3x schweren Ketten</two> und <two>3x leichten Ketten</two>. []
+- In der Zellbiologie: was heißt <one>Cvt-Pathway</one>? <one>Cytoplasm-to-vacuole targeting</one>. URL: https://en.wikipedia.org/wiki/Cytoplasm-to-vacuole_targeting []
+- Das <one>raue endoplasmatische Retikulum</one> <two>verdankt seine Bezeichnung ... </two>? Den vielen <one>Ribosomen</one>. URL: https://de.wikipedia.org/wiki/Endoplasmatisches_Retikulum#Raues_ER_(granul%C3%A4res_ER) []
+- Wie kann die <one>Funktion eines Ionenkanals</one> gemessen werden? Mit Hilfe der <one>patch clamp</one> Technik. URL: https://en.wikipedia.org/wiki/Patch_clamp []
+- <one>Folded proteins</one> <two>inside of a cell</two> <three>leave the ER where</three>? At <one>ER exit sites</one>. URL: https://pubmed.ncbi.nlm.nih.gov/30304445/ []
+- <one>Importins</one> <two>belong to which family</two>? <one>Karyopherins</one>. URL: https://en.wikipedia.org/wiki/Karyopherin []
+- The <one>plasma membrane</one> <two>contains how many layers of phospholipids</two>? <one>Two</one>. []
+- Wie wird <one>die Hülle einer Muskelfaser</one> <two>genannt</two>? <one>Sarkolemma</one>. URL: https://de.wikipedia.org/wiki/Muskulatur []
+- Vorläufer der <one>Ceramide</one>? <one>Sphingosine</one>. URL: https://de.wikipedia.org/wiki/Ceramide []
+- The <one>MPF</one> (<two>maturation promoting factor</two>) <three>consists of how many subunits</three>? <one>2</one>. []
+- Name one <one>lysosomal storage disease</one>. A: The <one>Tay Sachs disease</one>. URL: https://en.wikipedia.org/wiki/Tay%E2%80%93Sachs_disease []
+- Nenne <one>zwei zentrale, sekundäre Botenstoffe</one>. A: (1) <one>cAMP</one> (2) <one>cGMP</one> []
+- Name one <one>microtubule severing protein</one>. A: <one>Katanin</one>. <two>Easy to rememeber: it is named after the japanese sword katana after all</two>. URL: https://en.wikipedia.org/wiki/Katanin []
+- <one>Welche Aufgabe</one> hat die <two>kontraktile Vakuole</two>? <one>Überschüssiges Wasser</one> <two>wird über die kontraktile Vakuole aus der Zelle gepumpt</two>. URL: https://de.wikipedia.org/wiki/Kontraktile_Vakuole []
+- Was findet am <one>glatten ER</one> statt? Dies ist allgemein <one>der Ort der Lipidsynthese</one>. URL: https://de.wikipedia.org/wiki/Endoplasmatisches_Retikulum []
+- Name an <one>ER stress reaction</one>. A: The <one>unfolded protein response</one>, <two>UPR</two>. URL: https://en.wikipedia.org/wiki/Unfolded_protein_response []
+- The <one>Triskelion</one> is <two>made up of subunits called ... </two>? <one>Clathrin</one>. URL: https://en.wikipedia.org/wiki/Clathrin []
+- Kann das <one>26S-Proteasom</one> <two>im Zellkern gefunden werden</two>? <one>Ja</one>. []
+- Name an <one>enzyme</one> that plays <two>an important role in cellular energy homeostasis</two>. A: <one>AMPK</one> URL: https://en.wikipedia.org/wiki/AMP-activated_protein_kinase []
+- Finden wir <one>in Skelettmuskelzellen</one> <two>mehr ATP</two> oder <two>mehr Kreatinphosphat</two>? Mehr <one>Kreatinphosphat</one>. []
+- Does <one>organelle DNA</one> <two>replicate</two> even in <three>cells that do not divide</three>? <one>Yes</one>. []
+- Andere Bezeichnung für <one>zwischen den Zellen</one>? <one>Interstitiell</one>. URL: https://flexikon.doccheck.com/de/Interstiti []
+- Do <one>microfilaments</one> <two>have a plus and minus end</two>? <one>Yes</one>. URL: https://en.wikipedia.org/wiki/Microfilament []
+- Andere Bezeichnung für <one>Innendruck des Cytoplasmas</one>? <one>Turgor</one>. []
+- Haben <one>Zellen</one> normalerweise <two>mehr GTP</two> oder <two>mehr GDP</two>? <one>Mehr GTP</one>. []
+- Can <one>p53</one> be both <two>acetylated</two> AND <two>phosphorylated</two>, in principle? <one>Yes</one>. []
+- In der Zellbiologie steht die Abkürzung <one>CDK</one> für ... ? <one>Cyclin dependent kinase</one>. URL: https://en.wikipedia.org/wiki/Cyclin-dependent_kinase []
+- <one>Wieviel % der Proteine</one> einer <two>Leberzelle</two> werden <three>pro Stunde über Autophagy degradiert</three>? <one>1%</one>. []
+- Bei den Eukarya: <one>wie wirkt</one> <two>cAMP</two>? <one>Indirekt</one>, über die <two>Proteinkinase A</two>. URL: https://de.wikipedia.org/wiki/Cyclisches_Adenosinmonophosphat []
+- Name <one>a potent inhibitor of autophagy</one>. A: <one>Amino Acids</one>. URL: https://en.wikipedia.org/wiki/Autophagy []
+- How many <one>NPCs</one> does <two>a typical mammalian cell</two> have (<three>from-to</three>)? <one>3000-4000 NPCs</one>. []
+- <one>In einer eukaryoten Zelle</one>: ist eher das <two>ER</two> <three>näher am Zellkern</three> oder der <two>Golgi Komplex</two>? Das ER ist deutlich näher am Zellkern vorzufinden als der Golgi Komplex. []
+- <one>Welche Hypothese</one> konnte durch <two>Louis Pasteur</two> widerlegt werden? Die <one>Spontanzeugungshypothese</one>. URL: https://de.wikipedia.org/wiki/Spontanzeugung []
+- <one>Portaler Transport</one> innerhalb der Zelle ... ? Durch die <one>Kernporen des Zellkerns</one>. []
+- What is the <one>brain</one> <two>of the cell</two>? The <one>nucleus</one>. URL: URL: https://en.wikipedia.org/wiki/Cell_nucleus []
+- <one>Welche Zellen</one> bilden die <two>Myelinschicht</two>? Die <one>Gliazellen</one>. URL: https://de.wikipedia.org/wiki/Gliazelle []
+- Welches <one>Phospholipid</one> <two>trägt eine negative Ladung nach aussen hin</two>? <one>Phosphatidylserin</one>. URL: https://de.wikipedia.org/wiki/Phosphatidylserin []
+- An die <one>Kernmembran</one> schließt ... ? Das <one>Endoplasmatische Retikulum</one> (<two>ER</two>). []
+- Can <one>cells</one> <two>pick up other cells</two> through <three>endocytosis</three>? <one>Yes</one>. []
+- What is <one>the RNA component of SRP</one>? The <one>7SL-RNA</one>. URL: https://en.wikipedia.org/wiki/Signal_recognition_particle_RNA []
+- An <one>autophagic vesicle</one> <two>can fuse with ...</two>? A <one>lysosome</one>. []
+- <one>Welche Zellen</one> sind <two>gegenüber den Effekten einer ionisierenden Strahlen allgemein sehr empfindlich</two>? <one>Zellen</one> die <two>sehr Mitose-aktiv sind</two>. []
+- <one>How many</one> <two>different types of autophagy</two> <three>can be distinguished</three>? <one>Three</one>. []
+- In cell biology: the <one>ARF-GAP1</one> can do what? <one>ARF-GAP1</one> <two>can sense membrane curvature</two>. URL: https://en.wikipedia.org/wiki/ARFGAP1 []
+- <one>Integrine</one> <two>bestehen aus wievielen Untereinheiten</two>? <one>2</one> - <two>Integrine</two> sind somit <three>Heterodimere</three>. []
+- <one>Microtubules</one> <two>are nucleated at which end</two>? At their <one>minus (-) end</one>. []
+- Can <one>proteins</one> contain <two>multiple nuclear localization signal</two> (<three>NLS</three>) sequences? <one>Yes</one>. []
+- What is <one>the most important group of enzymes in the lysosome</one>? The <one>hydrolases</one>. URL: https://en.wikipedia.org/wiki/Lysosome []
+- <one>Cell division</one> <two>creates ... </two>? <one>New cells</one>. []
+- The <one>nucleoporins</one> in a cell often contain different types of ... <two>which two amino acids that are repeated</two>? (1) <one>F</one>: <two>Phenylalanine</two> (2) <one>G</one>: <two>Glycine</two> []
+- <one>Which class of enzymes</one> <two>trigger the events in the cell cycle</two>? <one>Kinases</one>. []
+- Andere Bezeichnung für <one>Mikrofilamente</one>? <one>Aktinfilamente</one>. URL: https://de.wikipedia.org/wiki/Mikrofilamente []
+- <one>DnaA-Protein</one> can be <two>activated by which molecule</two>? <one>ATP</one>. []
+- Nenne <one>das wichtigste</one> <two>monomere G-Protein</two>. A: Das <one>Ras-Protein</one>. URL: https://en.wikipedia.org/wiki/Ras_GTPase []
+- The <one>lysosomal membrane</one> has <two>a single</two> or <two>double phospholipid bilayer</two>? The <one>lysosomal membrane</one> has <two>a single phospholipid layer</two>. []
+- The fibrillar extension of <one>NPC proteins</one> (<two>nucleoporins</two>) contain many repeats of <three>which two amino acids</three>? <one>FG-repeats</one> (<two>Phenylalanine</two> and <two>Glycine</two>). []
+- Do <one>lipids</one> <two>flip-flop</two>? <one>No</one>. []
+- In cellbiology: what does the word <one>ERES</one> mean? <one>ER export site</one>. URL: https://www.researchgate.net/figure/8568278_fig3_Figure-3-Biogenesis-of-Golgi-and-the-ER-export-site-A-Cells-stably-expressing-the []
+- <one>Wo</one> speichert eine Zelle <two>Ca²⁺</two>? Im <one>Lumen des endoplasmatischen Reticulums</one>. []
+- <one>Welchen Durchmesser</one> haben <two>Ribosomen</two> (<three>von-bis</three>)? Etwa <one>20nm - 25nm</one>. URL: https://de.wikipedia.org/wiki/Ribosom#Aufbau_und_Arten []
+- <one>Microfilaments</one> <two>in a cell</two> derive from which <three>protein</three>? From <one>actin</one>. URL: https://en.wikipedia.org/wiki/Microfilament []
+- For <one>autophagy</one> to properly function: which <two>organelle</two> is <three>the most important</three>? The <one>lysosome</one>. []
+- In der Zellbiologie gibt es eine Technik namens <one>FRAP</one>. <two>Wofür steht diese Abkürzung</two>? <one>Fluorescence Recovery after Photobleaching</one>. URL: https://en.wikipedia.org/wiki/Fluorescence_recovery_after_photobleaching []
+- <one>Selenocystein</one> ist was genau? Ein <one>Cystein</one>, <two>bei dem die Schwefelgruppe</two> <three>durch ein reaktiveres Selenium-Atom ersetzt wurde</three>. []
+- Provide <one>another name for</one> <two>intracellular containers</two>. A: <one>Transport vesicles</one>. []
+- Do <one>chloroplast</one> <two>contain ribosomes</two>? <one>Yes</one>. They are smaller than the regular ribosomes though. []
+- Die <one>Motordomäne von Myrosin</one> <two>kann</two> <three>welche zwei Substanzen binden</three>? (1) <one>ATP</one> (2) <one>Actin</one> []
+- Was sind <one>speckles</one>? <one>Protein-Aggregate</one> <two>im Zellkern</two>. URL: https://www.uniprot.org/locations/SL-0186 []
+- Name something in cell biology that has a <one>triskelion structure</one>. A: <one>Clathrin</one>. URL: https://en.wikipedia.org/wiki/Clathrin []
+- <one>Which COP protein</one>, <two>COP I or COP II</two>, functions in <three>intra-Golgi trafficking</three>? <one>COP I</one>. []
+- Proteine die ins <one>Peroxisom</one> transportiert werden, <two>tragen die Signalsequenz am N-Terminus oder am C-Terminus</two>? Am <one>C-Terminus</one>. []
+- In <one>LDL endocytosis</one>: what does <one>LDL</one> stand for? <one>Low Density Lipoprotein</one>. []
+- <one>Average lifetime for a mitochondrium</one> <two>in a liver cell</two>? About <one>10 days</one>. []
+- The <one>ER lumen</one> <two>can store what</two>? The <one>ER lumen</one> <two>can store</two> <three>calcium</three> (<four>Ca²⁺</four>). []
+- <one>Wo</one> findet man <two>Kupffer cells</two>? In der <one>Leber</one>. URL: https://en.wikipedia.org/wiki/Kupffer_cell []
+- Wofür steht der Name <one>P-bodies</one> in der Zellbiologie? <one>Processing bodies</one>. URL: https://en.wikipedia.org/wiki/P-bodies []
+- Nenne <one>einen Prozess</one>, mit dem man <two>RNA-Aptamere herstellen kann</two>. A: <one>SELEX</one>. URL: https://en.wikipedia.org/wiki/Systematic_evolution_of_ligands_by_exponential_enrichment []
+- <one>Export</one> and <one>import receptors</one> <two>are structurally related</two>. <three>They belong to which family</three>? They belong to the family of <one>karyopherins</one>. URL: https://en.wikipedia.org/wiki/Karyopherin []
+- Are <one>Endosomes</one> <two>organelles</two>? <one>Yes</one>. []
+- <one>How</one> can <two>lipid rafts</two> <three>in a cell membrane</three> <four>be observed</four>? The <one>AFM</one> (<one>atomic force microscope</one>) <two>could be used for this purpose</two>. []
+- What is the <one>most abundant disaccharide</one> in Biology? <one>Sucrose</one> (this is actually <two>Saccharose</two>, but we prefer the term Sucrose in the english language). URL: https://en.wikipedia.org/wiki/Sucrose []
+- Ein Botenmolekül <one>will</one> eine Zelle beeinflussen. <two>Was braucht die Zelle hierfür unbedingt</two>? Einen <one>Rezeptor</one>. []
+- A <one>transport vesicles</one> in general <two>carries ... </two>? <one>Cargo</one>. []
+- <one>How</one> are <two>the proteins</two> that make up the <three>nuclear pore complex</three> <four>called</four>? The <one>nucleoporins</one>. URL: https://en.wikipedia.org/wiki/Nucleoporin []
+- What is the purpose of a <one>caveolae</one>? A <one>caveolae</one> <two>protects a cell from stretching</two>. URL: https://pubmed.ncbi.nlm.nih.gov/11551396/ []
+- <one>Why</one> do <two>caspases</two> <two>not instantly kill a cell</two>? Because <one>caspases</one> are synthesized as <two>inactive precursors</two>. []
+- Nenne einen <one>Inhibitor der Phosphodiesterase</one>. A: <one>Koffein</one>. URL: https://de.wikipedia.org/wiki/Coffein []
+- <one>Welches Protein</one> erreicht eine <two>Abschnürung von Vesikeln</two>? <one>Dynamin</one>. URL: https://de.wikipedia.org/wiki/Dynamine []
+- In cell biology: <one>ARF-GAP1</one> <two>senses what</two>? <one>Membrane curvature</one>. URL: https://en.wikipedia.org/wiki/ARFGAP1 []
+- <one>Tubulin subunits</one> (Alpha and Beta) <two>can bind what exactly</two>? <one>GDP</one> or <one>GTP</one>. []
+- Can <one>Integrins</one> bind <two>laminins</two>? <one>Yes</one>. []
+- <one>Water molecules</one> <two>passage into a cell</two> <three>via ... </three>? This can occur via <one>aquaporines</one>. URL: URL: https://en.wikipedia.org/wiki/Aquaporin []
+- Name an <one>actin motor</one>. A: <one>Myosin</one>. URL: https://en.wikipedia.org/wiki/Myosin []
+- <one>Welche Person</one> entdeckte das Phänomen <two>splicing</two>? <one>Joan Steitz</one>. URL: https://medicine.yale.edu/lab/steitz/ []
+- <one>Proteins</one> that <two>permanently reside in the lumen of the endoplasmic reticulum (ER)</two> seem to be distinguished from newly synthesized secretory proteins by the presence of the C-terminal sequence ... ? <one>KDEL</one>: <two>Lys-Asp-Glu-Leu</two>. []
+- How do we call <one>the tethering proteins of the Golgi complex</one>? <one>Golgins</one>. URL: https://pubmed.ncbi.nlm.nih.gov/12892780/ []
+- <one>Mikrotubuli</one> <two>sind am Centrosom</two> <three>+</three> oder <three>-</three>? <one>-</one> []
+- Was machen <one>GTPasen</one>? <one>GTPasen</one> <two>binden GTP</two> und <three>hydrolysieren dieses dann zu GDP</three>. URL: https://en.wikipedia.org/wiki/GTPase []
+- <one>Wie</one> wird die <two>PKA</two> (<two>Proteinkinase A</two>) <three>aktiviert</three>? Über <one>cAMP</one>. URL: https://en.wikipedia.org/wiki/Protein_kinase_A []
+- Was ist die "H & E Färbung"? Hämatolysin + Eosin.