medsci-skills 4.1.0

package/skills/write-paper/references/journal_profiles/PLOS_Medicine.md

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+# Journal Profile: PLOS Medicine
+
+## Journal Identity
+
+- **Full name**: PLOS Medicine
+- **Abbreviation**: PLoS Med
+- **Publisher**: Public Library of Science (PLOS)
+- **ISSN**: 1549-1277 (print), 1549-1676 (online)
+- **Frequency**: Continuous online publication (monthly issues)
+- **Impact Factor**: ~10.5 (JCR 2023), ranked among top general medicine/public health journals
+- **Open Access**: Full OA (APC ~$3,000; fee assistance available)
+- **Acceptance rate**: ~10%
+- **Peer review**: Single-blind; academic editors (section-specific) + external reviewers
+
+## Manuscript Types and Word Limits
+
+| Type | Body Word Limit | Abstract | References | Figures/Tables |
+|------|----------------|----------|------------|----------------|
+| Research Article | 3500 words | 300 words (structured) | No limit | No strict limit |
+| Meta-Research Article | 3500 words | 300 words (structured) | No limit | No strict limit |
+| Systematic Review & Meta-Analysis | 4000 words | 300 words (structured) | No limit | No strict limit |
+| Essay | 3000 words | ~150 words (unstructured) | No limit | 5 |
+| Perspective | 2000 words | None | 30 | 3 |
+| Guidelines and Guidance | 4000 words | 300 words | No limit | No strict limit |
+
+Word counts exclude abstract, references, and figure legends. PLOS has no strict reference or figure caps but encourages conciseness.
+
+---
+
+## Abstract Requirements
+
+**Structured abstract, 300 words maximum (Research Articles):**
+
+```
+Background: [Context, existing evidence, knowledge gap]
+Methods and Findings: [Study design, setting, participants, dates,
+    primary and secondary outcomes, key results with effect sizes,
+    CIs, P values, and study limitations — yes, limitations go here]
+Conclusions: [Main conclusion, implications for practice or policy]
+```
+
+**Critical**: PLOS Medicine uses a 3-heading abstract (Background, Methods and Findings, Conclusions). Uniquely, the "Methods and Findings" section must include key study limitations. The abstract should mention the study's limitations before the Conclusions heading.
+
+---
+
+## Required Sections (Research Article)
+
+### 1. Author Summary
+
+A 150-200 word plain-language summary (distinct from abstract), structured as:
+- **Why Was This Study Done?** (2-3 bullet points)
+- **What Did the Researchers Do and Find?** (2-3 bullet points)
+- **What Do These Findings Mean?** (2-3 bullet points including limitations)
+
+This is read by non-specialists and media; avoid jargon.
+
+### 2. Body Sections
+
+1. **Introduction** — brief (3-4 paragraphs); state the gap and end with study aim
+2. **Methods**
+   - Ethics statement (first paragraph): IRB/ethics approval, informed consent
+   - Study design: cite reporting guideline used (STROBE, CONSORT, PRISMA, etc.)
+   - Setting and participants: dates of enrollment, inclusion/exclusion criteria
+   - Variables and outcomes: primary and secondary defined
+   - Statistical analysis: pre-specified plan, software, handling of confounders and missing data
+   - Prospective protocol or analysis plan: registration or pre-registration encouraged
+3. **Results** — begin with participant flow; report primary outcome first
+4. **Discussion** — begin with key findings summary; include explicit limitations paragraph; end with implications for policy/practice
+
+### 3. Data Availability Statement
+
+Mandatory. Data must be publicly available or authors must explain restrictions. PLOS enforces data sharing more strictly than most journals.
+
+---
+
+## Statistical Reporting
+
+- Report exact P values (e.g., P = 0.03); use P < 0.001 below that threshold.
+- 95% CI required for all primary outcomes.
+- Effect sizes with units (absolute and relative measures).
+- For observational studies: report adjusted and unadjusted estimates; specify confounder selection method.
+- DAG (directed acyclic graph) encouraged for causal inference studies.
+- For meta-analyses: heterogeneity (I², tau²), publication bias assessment, sensitivity/subgroup analyses.
+- Multiple comparisons: state correction method or declare as exploratory.
+- Missing data: report proportion missing; describe handling (complete case, imputation).
+- Bayesian analyses accepted with prior justification.
+- Statistical software and version must be identified.
+- For prediction models: discrimination (AUC) and calibration required; TRIPOD checklist.
+- Reproducibility: analysis code sharing strongly encouraged.
+
+---
+
+## Figures
+
+- **No strict maximum** — but reviewers may request reduction if excessive
+- **Resolution**: 300 DPI minimum
+- **Format**: TIFF or EPS preferred; PDF acceptable
+- **Color**: Free (online-only journal)
+- **Supporting Information**: Unlimited supplementary figures, tables, methods, datasets
+- **Figure panels**: Label A, B, C with self-explanatory legends
+- **Flow diagrams**: CONSORT, PRISMA, or STARD as appropriate
+- **Data visualization**: Encourage informative plots over simple bar charts
+
+---
+
+## Common Rejection Reasons
+
+1. **Insufficient general medical/public health relevance** — findings must matter beyond one specialty or setting
+2. **Scope mismatch** — pure clinical/subspecialty work without broader implications
+3. **Methodological concerns** — inadequate adjustment for confounders, selection bias, or missing data
+4. **Reporting guideline non-compliance** — EQUATOR checklists strictly required
+5. **No data availability** — PLOS enforces open data; no plan = desk reject
+6. **Overclaiming in abstract** — limitations must be stated in abstract (not just Discussion)
+7. **Insufficient novelty for the field** — must advance knowledge meaningfully
+
+---
+
+## Cover Letter
+
+Must include:
+- Brief description of the study and its significance (2-3 sentences)
+- Statement of relevance to PLOS Medicine readership
+- Confirmation that the manuscript is not under consideration elsewhere
+- Data availability confirmation
+- Any relevant competing interests
+- Suggested academic editor or section (optional)
+
+---
+
+## AI Writing Disclosure Policy
+- **Requirement level:** Required (Permissive)
+- **Permitted scope:** All tasks permitted — AI/LLM tools may be used for writing, editing, data analysis, code generation, and other manuscript preparation tasks; AI cannot be listed as authors; authors retain full responsibility for accuracy and integrity of all content including AI-generated text
+- **Disclosure location:** Methods (or appropriate section) — must disclose the AI tool name, version, and how it was used; describe what content was generated or edited by AI; follows PLOS-wide AI policy
+- **AI-generated images:** Permitted with disclosure — AI-generated or AI-manipulated images must be explicitly disclosed; provide tool name, version, and prompts used; images must not misrepresent data
+- **Policy URL:** https://journals.plos.org/plosmedicine/s/submission-guidelines#loc-ai-assisted-technologies
+
+---
+
+## Author Guidelines URL
+
+https://journals.plos.org/plosmedicine/s/submission-guidelines
+
+---
+
+## Positioning
+
+| Feature | PLOS Medicine | JAMA Netw Open | BMC Medicine | BMJ Open |
+|---------|--------------|---------------|--------------|----------|
+| IF | ~10.5 | ~13.8 | ~7.5 | ~3.0 |
+| OA model | Full OA | Full OA | Full OA | Full OA |
+| APC | ~$3,000 | ~$3,500 | ~$3,690 | ~$2,590 |
+| Abstract style | 3-heading (limits in abstract) | 7-heading (JAMA format) | Structured (varied) | Structured (varied) |
+| Unique feature | Author Summary + open data | JAMA Network prestige | Fast review | High acceptance |
+| MA/SR | Strong fit | Good fit | Strong fit | Acceptable |
+| AI policy | Permissive (all uses OK) | Moderate (editing only) | ICMJE-standard | ICMJE-standard |
+| Global health | Core strength | Accepted | Good | Good |
+
+PLOS Medicine is appropriate when:
+- Study has clear public health or health policy implications
+- Systematic review or meta-analysis on a broadly relevant topic
+- Meta-research (research on research, reporting quality, publication bias)
+- Global health study with population-level impact
+- Study requiring permissive AI disclosure (AI-assisted analysis integral to methods)
+- Data sharing is fully possible (no proprietary restrictions)
+
+Not appropriate for: narrow subspecialty clinical studies, technical AI methodology without health impact, studies where data cannot be shared, case reports.

package/skills/write-paper/references/journal_profiles/RYAI.md

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+# Radiology: Artificial Intelligence (RYAI)
+
+## Journal Identity
+
+- **Full name**: Radiology: Artificial Intelligence
+- **Abbreviation**: Radiol Artif Intell
+- **Publisher**: Radiological Society of North America (RSNA)
+- **ISSN**: 2638-6100
+- **Frequency**: Bimonthly
+- **Impact Factor**: ~8.1 (2024)
+
+## Manuscript Types and Word Limits
+
+| Type | Abstract | Manuscript Body | Figures | Tables |
+|------|----------|----------------|---------|--------|
+| Original Research | 250 | 3500 | 7 | 5 |
+| Technical Note | 250 | 1500 | 4 | 3 |
+| Review Article | 250 | 5000 | 10 | 5 |
+| Letter to Editor | none | 500 | 1 | 1 |
+
+Word counts exclude abstract, references, figure legends, and tables.
+
+## Abstract Format
+
+Structured with four headings:
+1. **Purpose**
+2. **Materials and Methods**
+3. **Results**
+4. **Conclusion**
+
+Maximum 250 words. Must be self-contained.
+
+## Citation Style
+
+- Vancouver (numbered) style.
+- Numbered sequentially in order of first appearance in text.
+- Use superscript numbers in the manuscript body.
+- Format: Author(s). Title. Journal Abbreviation. Year;Vol(Issue):Pages.
+- List all authors if 6 or fewer; if 7+, list first 3 followed by "et al."
+
+## Keywords
+
+- 3-5 keywords required.
+- MeSH terms preferred.
+- Listed alphabetically.
+
+## Required Elements
+
+### For All Manuscripts
+- **Title page**: title, short title (50 chars), authors with affiliations, corresponding author, word count, number of figures/tables/references.
+- **Key Points**: Not required (unlike AJR).
+- **Data Availability Statement**: Required. Must specify whether data and code are available and under what conditions.
+- **Author Contributions**: CRediT taxonomy required.
+- **Conflict of Interest Disclosures**: Required for all authors.
+- **Funding**: Grant numbers and funding sources.
+
+### For AI Studies (Mandatory)
+- **CLAIM Checklist**: Must be completed and submitted as supplemental material for any study involving AI/ML in medical imaging.
+- **AI Disclosure in Methods**: Must describe any use of AI tools in the research process (data collection, analysis, writing assistance). Specific tools and versions must be named.
+- **AI Disclosure in Acknowledgments**: Must acknowledge AI writing assistance if used, specifying the tool and its role.
+- **Code Availability**: Strongly encouraged. GitHub repository or equivalent.
+- **Model Card**: Encouraged for studies introducing new AI models.
+
+## Reporting Guidelines
+
+Match study type to required checklist:
+
+| Study Type | Required Checklist |
+|------------|-------------------|
+| Diagnostic accuracy (AI) | STARD-AI |
+| Prediction model | TRIPOD+AI |
+| Any AI study in imaging | CLAIM 2024 |
+| Randomized trial with AI | CONSORT-AI |
+| Systematic review of AI | PRISMA 2020 |
+
+Multiple checklists may apply (e.g., CLAIM + STARD-AI for a diagnostic AI study).
+
+## Supplemental Materials
+
+- Strongly encouraged.
+- Can include additional tables, figures, methods details, code.
+- Supplemental material is peer-reviewed.
+- Common supplements: expanded methods, additional performance metrics, subgroup analyses, CLAIM checklist.
+
+## Formatting Notes
+
+- Double-spaced, 12-point font.
+- Line numbers required on the manuscript.
+- Pages numbered consecutively.
+- Abbreviations defined at first use in both abstract and body (independently).
+- SI units preferred; conventional units acceptable with SI in parentheses.
+
+## Statistical Reporting
+
+- Report exact p-values (e.g., P = .034); use P < .001 only when value is below that threshold. Never report only "P < .05".
+- 95% CI required for all primary performance metrics (AUC, sensitivity, specificity, accuracy).
+- For AI model comparisons: use DeLong test for AUC comparison; McNemar test for paired sensitivity/specificity.
+- Calibration must accompany discrimination for prediction models: calibration plot + Hosmer-Lemeshow or calibration slope/intercept.
+- Subgroup performance metrics required for fairness assessment (CLAIM requirement).
+- Effect sizes with units; avoid "significant" without accompanying statistics.
+- Statistical software and version must be named in Methods.
+- Statistical review for all accepted manuscripts.
+
+## Review Process
+
+- Single-blind peer review.
+- Typical first decision: 4-6 weeks.
+- Revisions usually due within 60 days.
+
+## Special Considerations for Education-Research Manuscripts
+
+- Paper 1 (S5 Multi-agent Validation) and Paper 2 (MLLM Image Reliability) are strong fits for RYAI.
+- CLAIM checklist is mandatory for both.
+- Emphasis on reproducibility: pipeline code, prompt templates, and evaluation criteria should be described in detail or provided as supplements.
+- For LLM/MLLM studies: model version, API date, temperature settings, prompt text (or reference to supplement) must be reported in Methods.
+
+---
+
+## AI Writing Disclosure Policy
+- **Requirement level:** Required
+- **Permitted scope:** Language editing only — AI/LLM tools may assist with language editing and manuscript preparation but cannot be listed as authors; must not generate scientific content, interpret data, or draw conclusions
+- **Disclosure location:** Methods + Acknowledgments — must describe the AI tool name, version, and specific role in both the Methods section (under "AI Disclosure in Methods") and Acknowledgments (under "AI Disclosure in Acknowledgments"); this is distinct from AI used as the research subject
+- **AI-generated images:** Banned — AI-generated or AI-manipulated images in figures are not permitted; AI models studied as research subjects must follow CLAIM checklist reporting
+- **Policy URL:** https://pubs.rsna.org/page/ai-policy

package/skills/write-paper/references/journal_profiles/Radiology.md

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+# Journal Profile: Radiology (RSNA)
+
+## Basic Information
+
+- **Publisher:** Radiological Society of North America (RSNA)
+- **Impact Factor:** ~19.0 (2023–2024) — flagship journal of radiology
+- **Scope:** Original research in diagnostic and interventional radiology; any imaging modality; clinical and translational
+- **Sister journals:** Radiology:AI (AI-specific), Radiology:Cardiothoracic, RadioGraphics (educational)
+- **Open Access:** Optional (RSNA Open Access); standard subscription model
+- **Language:** American English
+
+---
+
+## Manuscript Types and Word Limits
+
+| Type | Body Word Limit | Abstract | Figures | References |
+|------|----------------|----------|---------|------------|
+| Original Research | 3000 words | 250 words | **6 (strictly enforced)** | 40 |
+| Review | 4000 words | 250 words | 8 | 60 |
+| Technical Developments | 3000 words | 250 words | 6 | 30 |
+| Case Reports | 1000 words | None | 4 | 8 |
+| Letters | 500 words | None | 1 | 5 |
+
+**⚠️ 6-figure limit is strictly enforced.** Supplementary figures are allowed and should be used for additional cases, subgroup analyses, and detailed methods.
+
+---
+
+## Abstract Requirements
+
+**Structured abstract, 250 words maximum:**
+
+```
+Background: [Clinical problem and why it matters — 1–2 sentences]
+Purpose: [Specific aims — usually 1 sentence]
+Materials and Methods: [Design, population, exposure/index test, outcome,
+                        statistical analysis]
+Results: [Primary results with statistics, 95% CI, exact p-value;
+          secondary results briefly]
+Conclusion: [Main conclusion — 1–2 sentences]
+```
+
+---
+
+## Required Journal-Specific Elements
+
+### 1. Summary Statement
+
+A single sentence (≤ 50 words) that captures the essential finding. Placed immediately before the abstract.
+
+"[Index test/intervention] [demonstrated/showed/reduced] [outcome] in [population], suggesting [clinical implication]."
+
+This is the first thing an editor reads. Make it compelling and specific.
+
+### 2. Advances in Knowledge
+
+3 bullet points, placed at the end of the manuscript (after Discussion, before References). Each bullet ≤ 2 sentences.
+
+Cover: (a) methodological advance, (b) main clinical finding with effect size, (c) implication.
+
+Example:
+```
+Advances in Knowledge
+■ A deep learning model for detecting pulmonary embolism on CT angiography
+  was trained on 5000 examinations across three institutions.
+■ The model achieved a sensitivity of 91% (95% CI: 87–94%) and specificity
+  of 96% (95% CI: 93–98%), comparable to expert radiologists.
+■ This externally validated model may support radiologist workflow in high-
+  volume centers by flagging urgent examinations.
+```
+
+---
+
+## Required Sections (Original Research)
+
+1. **Introduction** — brief (200–300 words); end with explicit purpose statement
+2. **Materials and Methods**
+   - Ethics: IRB number + consent or waiver statement
+   - Study Design: state prospective or retrospective
+   - Participants: inclusion/exclusion criteria, flowchart
+   - Image Analysis: technique, readers, blinding
+   - Statistical Analysis: software (R or SAS; version), tests, significance threshold
+3. **Results** — primary outcome first, then secondary
+4. **Discussion** — 3–4 paragraphs; Limitations as penultimate paragraph
+5. **Conclusion** — brief (1–2 sentences)
+6. **Advances in Knowledge** — 3 bullets (see above)
+
+---
+
+## Statistical Reporting
+
+Radiology endorses **SAMPL guidelines** (Statistical Analyses and Methods in the Published Literature):
+- Report exact p-values (P = .034), never P < .05
+- 95% CI for all primary outcomes
+- Effect sizes with units
+- NNT/NNH for clinical outcomes where applicable
+- Diagnostic accuracy: sensitivity, specificity, AUC, all with 95% CI
+
+---
+
+## Differentiation from Radiology:AI
+
+| Dimension | Radiology | Radiology:AI |
+|-----------|-----------|-------------|
+| Focus | Clinical radiology (any modality) | AI/ML methodology and validation |
+| AI papers | Only if AI is validated clinically | AI at any development stage |
+| Required novelty | Large prospective or multi-center | Can be single-center |
+| Reporting guideline | SAMPL | CLAIM |
+| Acceptance bar | ~5–8% | ~15–20% |
+| Impact factor | ~19 | ~8 |
+
+**Use Radiology if:** AI is fully clinically validated, study is large/multi-center, primary novelty is clinical not technical.
+**Use Radiology:AI if:** Paper is primarily about AI methodology, training, validation, or comparison.
+
+---
+
+## Figures
+
+- **Maximum 6 figures** — plan carefully; multi-panel counts as one figure
+- **Resolution:** 300 DPI (600 DPI for line art)
+- **Format:** EPS or TIFF
+- **Figure panels:** Label A, B, C, etc.; panels should be self-explanatory from legend
+- **Supplementary figures:** Unlimited; use freely for additional cases, ROC curves, calibration plots
+
+---
+
+## Common Rejection Reasons
+
+1. **Below novelty threshold** — Radiology expects findings that change practice or open new research directions; replication studies rarely accepted unless very large-scale
+2. **Figure limit exceeded** — submitting 8 figures will cause desk rejection
+3. **Missing Summary statement or Advances in Knowledge** — reviewed immediately on submission
+4. **Underpowered study** — sample sizes of N < 200 are unusual for Radiology original research; N < 100 almost never accepted
+5. **Retrospective single-center** — not automatically rejected, but must provide very strong novelty
+6. **Overclaiming in Abstract** — editors are sensitive to "first," "largest," "gold standard" language without justification
+7. **Statistical reporting errors** — Radiology statistical editors check carefully
+
+---
+
+## Cover Letter
+
+Must include:
+- Summary statement (same as in manuscript)
+- Statement that all authors approved the submission
+- Disclosure of any related manuscripts under review
+- Patient consent/IRB statement (brief)
+
+Suggested reviewers: 3–5 names with email addresses (RSNA specifically encourages this).
+
+---
+
+## Author Guidelines URL
+
+https://pubs.rsna.org/page/radiology/submission-guidelines
+
+---
+
+## Positioning
+
+Radiology is appropriate when:
+- Large prospective or multi-center study (N ≥ 500 preferred)
+- Practice-changing finding in major disease category (lung cancer, stroke, liver disease)
+- Head-to-head comparison demonstrating superiority of a new modality/technique
+- Landmark AI study with external validation and clinical endpoint
+
+Not appropriate for: small retrospective series, incremental technical improvements, studies limited to a rare condition (unless first of its kind with major impact).
+
+---
+
+## AI Writing Disclosure Policy
+- **Requirement level:** Required
+- **Permitted scope:** Language editing only — AI/LLM tools may assist with language polishing and editing but cannot be listed as authors and must not generate scientific content, interpret data, or draw conclusions
+- **Disclosure location:** Methods + Acknowledgments — describe the AI tool, version, and how it was used; RSNA requires disclosure in both the Methods section and Acknowledgments
+- **AI-generated images:** Banned — AI-generated or AI-manipulated images in figures are not permitted; AI use in image analysis as part of the study methodology is acceptable and must be described in Methods
+- **Policy URL:** https://pubs.rsna.org/page/ai-policy

package/skills/write-paper/references/journal_profiles/Skeletal_Radiology.md

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+# Journal Profile: Skeletal Radiology
+
+## Journal Identity
+
+- **Full name**: Skeletal Radiology
+- **Abbreviation**: Skeletal Radiol
+- **Publisher**: Springer Nature (International Skeletal Society)
+- **ISSN**: 0364-2348 (print), 1432-2161 (online)
+- **Frequency**: Monthly (12 issues/year)
+- **Impact Factor**: ~2.1 (JCR 2023)
+- **Open Access**: Hybrid (Springer transformative agreements may cover OA)
+- **Acceptance rate**: ~30-35%
+- **Peer review**: Single-blind; typically 2 reviewers
+
+## Manuscript Types and Word Limits
+
+| Type | Body Word Limit | Abstract | References | Figures/Tables |
+|------|----------------|----------|------------|----------------|
+| Scientific Article | 3500 words | 250 words (structured) | 35 | 6 |
+| Review Article | 5000 words | 250 words | 60 | 10 |
+| Case Report | 1500 words | 150 words (unstructured) | 10 | 6 |
+| Technical Report | 2000 words | 150 words (unstructured) | 15 | 4 |
+| Pictorial Essay | 3000 words | 200 words | 20 | 12 |
+| Test Yourself | 1000 words | None | 5 | 6 |
+| Letter to the Editor | 500 words | None | 5 | 1 |
+
+Word counts exclude abstract, references, tables, and figure legends.
+
+---
+
+## Abstract Requirements
+
+**Structured abstract for Scientific Articles, 250 words maximum:**
+
+```
+Objective: [Study aim]
+Materials and Methods: [Design, population, imaging, analysis]
+Results: [Key findings with statistics]
+Conclusion: [Main conclusion — 1-2 sentences]
+```
+
+**Unstructured abstract for Case Reports and Technical Reports, 150 words.**
+
+---
+
+## Required Sections (Scientific Article)
+
+1. **Introduction** — clinical context, gap, purpose (2-3 paragraphs)
+2. **Materials and Methods**
+   - Study Design: IRB, retrospective/prospective
+   - Patient Population: inclusion/exclusion, time period
+   - Imaging Protocol: modality, scanner, sequence parameters
+   - Image Analysis: readers, blinding, measurement methods
+   - Statistical Analysis: software, tests
+3. **Results** — demographics, imaging findings, diagnostic performance
+4. **Discussion** — comparison with literature, clinical implications, limitations
+5. **Conclusion**
+
+---
+
+## Statistical Reporting
+
+- Report exact p-values; use p < 0.001 below that threshold.
+- 95% CI for primary outcomes.
+- For diagnostic accuracy: sensitivity, specificity, AUC with 95% CI.
+- Inter-reader agreement: ICC with model/type, or kappa with weighting scheme.
+- For measurement studies: Bland-Altman with limits of agreement, SEM, MDC.
+- Statistical software and version must be identified.
+
+---
+
+## MSK-Specific Requirements
+
+### Imaging Protocol
+
+- MRI: field strength, coil, sequences (PD FS, T1, T2, contrast-enhanced), slice thickness
+- CT: scanner, kVp, reconstruction kernel, reformats
+- US: transducer frequency, dynamic maneuvers
+- Radiography: projections, positioning
+
+### Anatomy and Classification
+
+Use standardized MSK terminology and classification systems:
+- Fractures: AO/OTA classification
+- Tumors: WHO classification with imaging-pathology correlation
+- Arthritis: grading systems (Kellgren-Lawrence, OMERACT for US)
+- Sports injuries: standardized grading (e.g., muscle injury: British Athletics classification)
+
+---
+
+## Figures
+
+- **Maximum 6 figures/tables** for scientific articles; **12 for Pictorial Essays**
+- **Resolution**: 300 DPI minimum
+- **Format**: TIFF, EPS, JPEG
+- **Color**: Free online
+- **MSK imaging conventions**: appropriate window/level, anatomical annotations, comparison with contralateral side when relevant
+
+---
+
+## Common Rejection Reasons
+
+1. **Overlap with AJR or Radiology MSK content** — needs unique MSK-specific contribution
+2. **Case reports too common** — must be genuinely rare or educationally unique
+3. **Missing imaging protocol** — essential for MSK imaging reproducibility
+4. **Small sample for diagnostic accuracy** — needs enough cases per pathology category
+5. **No inter-reader agreement** for subjective findings
+
+---
+
+## Cover Letter
+
+Should include:
+- Relevance to MSK radiology
+- Key finding summary
+- Statement of originality
+
+---
+
+## Author Guidelines URL
+
+https://www.springer.com/journal/256/submission-guidelines
+
+---
+
+## Positioning
+
+Skeletal Radiology is appropriate when:
+- MSK imaging study (tumor, sports, arthritis, metabolic bone disease)
+- AI applied to MSK imaging with diagnostic evaluation
+- Case report of rare MSK pathology with high-quality imaging
+- MRI technique validation for MSK application
+- Pictorial essay on MSK imaging topic
+
+Not appropriate for: non-MSK imaging, purely surgical outcomes without imaging focus, orthopedic biomechanics without imaging component.