medsci-skills 4.1.0

package/skills/write-paper/references/journal_profiles/European_Journal_of_Preventive_Cardiology.md

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+# Journal Profile: European Journal of Preventive Cardiology
+
+## Journal Identity
+
+- **Full name**: European Journal of Preventive Cardiology
+- **Abbreviation**: Eur J Prev Cardiol (EJPC)
+- **Publisher**: Oxford University Press (on behalf of the European Association of Preventive Cardiology and the European Society of Cardiology)
+- **ISSN**: 2047-4881 (online)
+- **Frequency**: 18 issues/year (monthly plus supplements)
+- **Impact Factor**: ~8 (recent JCR; verify at submission)
+- **Open Access**: Hybrid (subscription default with optional Gold OA via OUP open-access portal; specific APC not published on the Guidelines page — verify at OUP licensing)
+- **Acceptance rate**: Not published; broadly estimated 15–25% for Full Research after editorial triage
+- **Peer review**: Single-blind; methodology-heavy submissions undergo statistical review
+
+## Manuscript Types and Word Limits
+
+| Type | Body Word Limit | Abstract | References | Figures/Tables |
+|------|----------------|----------|------------|----------------|
+| Full Research Paper | 5,000 words | 250 (structured) | 100 max | 6 max |
+| Clinical Practice / Education | 5,000 words | 250 (structured) | 40 max | 6 max |
+| Review | 8,700 words | 250 (structured or unstructured) | 100 max | varies |
+| Editorial | 1,300 words | none | 10 max | 1 illustration |
+| Rapid Communication | 1,000 words | none | 10 max | 1 |
+| Letter to the Editor | 700 words | none | 5 max | 1 |
+| Cardialogue | 3,500 words | varies | 60 max | 1 per section |
+
+Word counts exclude abstract, references, tables, and figure legends.
+
+---
+
+## Abstract Requirements
+
+**Structured abstract, 250 words maximum, with 4 headings:**
+
+```
+Aims: [Specific research question or hypothesis tested]
+Methods: [Design, setting, population, exposures, outcomes, statistical approach]
+Results: [Primary results with effect sizes, 95% CIs, P values; N analyzed]
+Conclusion: [Direct answer to Aims with clinical implication]
+```
+
+The first heading is **Aims** (not Background or Objectives) — a characteristic ESC-family stylistic choice. Reviewers and the editorial portal will flag missing-Aims abstracts.
+
+---
+
+## Required Journal-Specific Elements
+
+### 1. Graphical Abstract / Central Figure
+
+Strongly encouraged for all Full Research papers. A square or landscape figure conveying the main scientific message; uploaded as a separate file at submission. Counts toward figure cap.
+
+### 2. Tweetable Abstract
+
+Submitting authors are asked to provide a one- or two-sentence summary suitable for social-media dissemination (under 280 characters including the journal handle).
+
+### 3. Article Information
+
+- Author affiliations with department, institution, city, country
+- Corresponding author with full contact details
+- Funding statement with grant identifiers
+- Disclosures: per-author ICMJE conflicts
+- Data availability statement
+- Ethical statement (IRB or equivalent + informed consent)
+
+---
+
+## Required Sections (Full Research Paper)
+
+1. **Introduction** — concise (2–3 paragraphs) with clear gap and aims statement
+2. **Methods**
+   - Ethics approval with body name
+   - Study design and setting
+   - Participants and eligibility
+   - Variables / definitions (especially relevant for preventive epidemiology — risk factor definitions and cutpoints)
+   - Outcomes (primary, secondary, exploratory clearly distinguished)
+   - Statistical analysis with explicit software and versions
+   - Sample size or power justification
+3. **Results** — STROBE flow; primary outcome before secondary; structured paragraphs for each endpoint
+4. **Discussion** — dedicated Strengths and Limitations subsections; conclude with public-health and clinical implications
+5. **Conclusion** — brief, no overclaiming
+
+---
+
+## Statistical Reporting
+
+- Exact P values to 3 decimal places; P < 0.001 below threshold
+- 95% CI for all primary effect estimates
+- Effect sizes (HR, OR, mean difference, absolute risk difference)
+- Proportional-hazards assumption check when Cox regression is used
+- Competing-risks framework where appropriate
+- Sensitivity analyses for major analytic choices (missing data, alternative cutpoints, exposure misclassification)
+- Prevention-focused outcomes: report both relative and absolute measures (RR and ARR/NNT) when feasible
+- Software and version reported
+
+---
+
+## Figures
+
+- **Maximum 6 figures/tables combined** for Full Research
+- Resolution: 300 DPI minimum
+- Format: TIFF, EPS, PDF
+- Color: encouraged (no fee for online publication)
+- Graphical abstract / central figure: encouraged
+- Supplementary material: online-only supplement permitted
+
+---
+
+## Common Rejection Reasons
+
+1. **Insufficient prevention framing** — manuscripts framed primarily as "outcomes" without a prevention/risk-factor angle are redirected
+2. **Single-center cohort without external comparison** — preferred design is multicenter or population-based; single-center papers must justify generalizability
+3. **Missing PH assumption check or sensitivity analysis** — methodology bar is high
+4. **Overclaiming on modest event counts** — wide CI estimates narrated without exploratory qualifier
+5. **Abstract heading mismatch** — using Background/Objectives/Methods/Results/Conclusions instead of Aims/Methods/Results/Conclusion
+6. **AI policy non-compliance** — undisclosed AI use or AI listed as author
+7. **Reference style violations** — failing to follow first-6-then-et-al rule
+
+---
+
+## Cover Letter
+
+Must include:
+- Brief statement of novelty and prevention relevance (2–3 sentences)
+- Confirmation manuscript is not under consideration elsewhere
+- Confirmation all authors meet ICMJE criteria
+- Disclosure of related manuscripts (same cohort, same group)
+- Suggested reviewers (3–5; senior PI should curate)
+- **AI disclosure statement** at point of submission (in the cover letter itself per the journal's policy — see AI section below)
+
+---
+
+## AI Writing Disclosure Policy
+
+- **Requirement level**: Required
+- **Verbatim policy**: "Natural language processing tools driven by artificial intelligence (AI) do not qualify as authors, and the Journal will screen for them in author lists. The use of AI (for example, to help generate content or images, write code, process data, or for translation) should be disclosed in a cover letter at the point of submission and explained in full in a Methods or Acknowledgements section."
+- **Disclosure location**: **Both** the cover letter (at submission) and a Methods or Acknowledgements section (in-manuscript)
+- **AI-generated images**: Covered by the same disclosure requirement; reviewer screening applies
+- **Policy URL**: https://academic.oup.com/eurjpc/pages/general-instructions
+
+---
+
+## Submission Portal
+
+https://www.editorialmanager.com/ejpc/default.aspx
+
+---
+
+## Author Guidelines URL
+
+https://academic.oup.com/eurjpc/pages/general-instructions
+
+---
+
+## Positioning
+
+| Criterion | EJPC | JACC: Advances | JAHA | NMCD |
+|-----------|------|----------------|------|------|
+| **Society** | ESC/EAPC | ACC | AHA | independent (Elsevier) |
+| **Impact Factor** | ~8 | not indexed yet | ~5 | ~3.9 |
+| **Open Access** | Hybrid | Full Gold OA | Full Gold OA | Hybrid |
+| **Geographic stance** | Europe-centric (welcomes non-EU data) | Global | Global, NA-centric | International |
+| **Primary framing** | Prevention, risk factors, rehabilitation | Cardiovascular broad | Cardiovascular broad | Cardio-metabolic (nutrition crossover) |
+| **Event-count tolerance** | Moderate; favors clear gradient and clean prevention narrative | Moderate | Moderate–high | Moderate |
+| **Abstract first heading** | Aims | Background | Background | Background and Aims |
+| **AI disclosure location** | Cover letter + Methods/Acknowledgements | Pre-references declaration | Methods | Pre-references declaration |
+| **Word cap (Original)** | 5,000 (text only) | 5,000 (incl. refs + legends) | none stated | 4,000 |
+
+**Choose EJPC when:**
+- Primary prevention, risk-factor clustering, or rehabilitation is the dominant framing
+- Transition or trajectory analyses with clear prevention implications
+- ESC/EAPC ecosystem visibility matters (European clinical-guidelines audience)
+- Manuscript can be tightly framed around a 4-heading Aims-led abstract
+
+**Choose JACC: Advances instead when:**
+- Framework application (e.g., AHA 2023 CKM staging) is the central methodological contribution and ACC ecosystem reach matters
+- Manuscript benefits from Gold OA visibility over hybrid
+
+**Choose JAHA instead when:**
+- Cross-modality cardiovascular–cerebrovascular framing
+- Negative or hypothesis-generating findings benefit from JAHA's higher tolerance
+
+**Choose NMCD instead when:**
+- Nutrition / metabolic intervention is integral to the exposure or interpretation
+- Cardio-metabolic-nutrition crossover audience matters more than ESC visibility
+
+---
+
+## Verification Notes
+
+Audit performed 2026-05-20. Sources opened:
+- Homepage: https://academic.oup.com/eurjpc (ISSN, society sponsorship, author-guidelines link)
+- General Instructions: https://academic.oup.com/eurjpc/pages/general-instructions (article types, word limits, abstract structure, references, AI policy verbatim, submission portal)

package/skills/write-paper/references/journal_profiles/European_Radiology.md

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+# Journal Profile: European Radiology
+
+## Basic Information
+
+- **Publisher:** Springer (Springer-Verlag GmbH)
+- **Society:** European Society of Radiology (ESR)
+- **Impact Factor:** ~7.0 (2023–2024)
+- **Scope:** All subspecialties of diagnostic and interventional radiology; AI/machine learning in radiology
+- **Open Access option:** Yes (Springer Open Choice); fully OA version: European Radiology Experimental
+- **Language:** English (British English preferred)
+
+---
+
+## Manuscript Types and Word Limits
+
+| Type | Body Word Limit | Abstract | Figures | Tables | References |
+|------|----------------|----------|---------|--------|------------|
+| Original Article | 3500 words | 250 words | 8 (+ supplementary) | 6 | 40 |
+| Review Article | 5000 words | 250 words | 10 | 6 | 80 |
+| Technical Note | 2000 words | 150 words (unstructured) | 5 | 4 | 20 |
+| Case Report | 1500 words | 200 words | 6 | 2 | 15 |
+| Letter to Editor | 600 words | None | 2 | 1 | 5 |
+
+*Word count excludes abstract, references, figure legends, and table captions.*
+
+---
+
+## Abstract Requirements
+
+**Structured abstract, 250 words maximum:**
+
+```
+Objectives: [One sentence: what was studied]
+Methods: [Study design, participants, index test, reference standard, outcomes]
+Results: [Key results with statistics, 95% CI]
+Conclusions: [Main conclusion and clinical relevance]
+Key Points: [3 bullet points — required, see below]
+```
+
+**Key Points** — 3 mandatory bullet points immediately after the abstract body:
+
+- Maximum 85 characters each
+- Written as declarative statements in present tense
+- Cover: what was done (1), main finding (2), clinical implication (3)
+- Bold the most important word or phrase in each bullet
+
+Example:
+```
+Key Points
+• [What was done] CT-based radiomics distinguishes malignant from benign thyroid nodules
+  with an AUC of 0.87.
+• [Finding] The model outperforms size-based criteria (AUC 0.62, P < .001).
+• [Implication] Radiomics may reduce unnecessary biopsies for indeterminate nodules.
+```
+
+---
+
+## Style Requirements
+
+### British English
+
+Use British English throughout:
+- colour (not color), characterise (not characterize), optimise (not optimize)
+- focussed (not focused, though both acceptable)
+
+### Statistical Reporting
+
+European Radiology endorses EQUATOR reporting guidelines. Specify:
+- Exact p-values to 3 decimal places (P = .034, not P < .05); values < .001 reported as P < .001
+- 95% confidence intervals in parentheses
+- Effect sizes with units
+
+### Number Formatting
+
+- Decimal separator: period (not comma) — European Radiology uses standard English number format
+- P values: no space between P and = (P = .034)
+- Percentages: [value]% without space
+
+---
+
+## Required Sections (Original Article)
+
+1. **Objectives** (not "Introduction" — European Radiology uses "Objectives")
+2. **Methods** — Ethics approval, study design, participants, imaging, analysis, statistics
+3. **Results**
+4. **Discussion** — Typically includes Limitations as a subsection
+5. **Conclusion** — Brief, final paragraph
+
+### Ethics Statement
+
+Required in all original articles involving human subjects or animals:
+
+"This retrospective study was approved by the [Institutional name] Ethics Committee (approval number [XXX]) with waiver of informed consent."
+
+or
+
+"All procedures performed in this study were approved by the [Institutional name] Institutional Review Board (approval number [XXX]). Written informed consent was obtained from all participants."
+
+---
+
+## Figure Requirements
+
+- **Resolution:** 300 DPI minimum (600 DPI for line art)
+- **Format:** TIFF or EPS preferred; JPEG acceptable for photographs
+- **Dimensions:** Column width 84 mm (single) or 174 mm (double) at 300 DPI
+- **Font in figures:** 8–10 pt, consistent typeface (Helvetica preferred)
+- **Color figures:** Free in online version; print color charged — design for both
+
+---
+
+## Visual Abstract / Graphical Abstract
+
+- **Status:** Mandatory from first revision for all Original Articles (January 2025)
+- **Reference:** Kelly BS. Eur Radiol 2025;35:5875–5877. doi:10.1007/s00330-025-11555-8
+- **Template:** EURA-GA-Jan2025.pptx (download from journal website)
+- **Format:** Landscape, single page, 16:9
+- **Structure:** Title → Hypothesis/Question → Methodology + Visual element → Badges (cohort, modality, center) → Main finding → Citation
+- **Generation:** `/make-figures` with `--template european_radiology`
+- **Visual element:** Use the study's actual figure (ROC curve, flow diagram). The editorial states these abstracts should "complement and elevate" the research, not just decorate it.
+
+---
+
+## Common Rejection Reasons
+
+1. **Incremental contribution** — must advance the field beyond existing literature; "largest series" is not sufficient without novel methodology or insight
+2. **Key Points missing or poorly written** — editors check these immediately
+3. **Word count exceeded** — strictly enforced; no tolerance for +10% over limit
+4. **No EQUATOR checklist** — must upload completed checklist (STROBE, STARD, TRIPOD, etc.) with submission
+5. **Underpowered study** — European Radiology expects adequate sample sizes; single-center studies with <100 participants rarely accepted for original articles
+6. **Statistical errors** — incomplete reporting of CIs, missing paired analyses for paired data
+7. **British English violations** — minor but reviewers flag it
+
+---
+
+## Cover Letter Tips
+
+- Address to: "Dear Editor-in-Chief"
+- State the manuscript type and article category
+- Confirm no prior submission/publication elsewhere
+- Mention if data sharing is available (Data Availability Statement)
+- Suggest 3–5 potential reviewers (names, institutions, email) — strongly encouraged by European Radiology
+
+---
+
+## Author Guidelines URL
+
+https://www.springer.com/journal/330/submission-guidelines
+
+---
+
+## Positioning
+
+European Radiology is well-suited for:
+- Multi-center European (or international) studies
+- AI/radiomics studies with clinical validation
+- Technical advances with proof-of-concept validation
+- Diagnostic accuracy studies with adequate sample size (typically N ≥ 200)
+
+Not well-suited for: small single-center series (< 50 patients), case reports unless highly unusual, studies where the only novelty is a larger sample of an already well-validated technique.

package/skills/write-paper/references/journal_profiles/Hepatology_Communications.md

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+# Journal Profile: Hepatology Communications
+
+## Journal Identity
+- **Full name:** Hepatology Communications
+- **Abbreviation:** Hepatol Commun
+- **Publisher:** Wolters Kluwer Health for AASLD (American Association for the Study of Liver Diseases)
+- **ISSN:** 2471-254X (online-only)
+- **Frequency:** Continuous publication, monthly issues
+- **Open Access:** Mandatory full OA, CC BY or CC BY-NC-ND
+- **Acceptance rate:** ~30–35 % (estimated; verify at editor reports)
+- **Peer review:** Anonymous; manuscripts are screened by Editor-in-Chief for quality + relevance before sending out for review. Papers transferred from other AASLD/Wiley journals may carry portable peer review.
+
+## Manuscript Types and Word Limits
+
+| Type | Body Word Limit | Abstract | References | Figures/Tables |
+|------|----------------|----------|------------|----------------|
+| Original Research Article | 5,000 (excluding refs) | 275 words structured | 50 | 8 (additional non-essential figures/tables in SDC) |
+| Review | 5,000 (excluding refs) | 275 words structured | unlimited (selective) | 8 |
+| Editorial / Viewpoint | 1,500 (incl. refs) | — | 10 | 1 figure or table |
+| Research Letter | 1,000 (main text only) | None | 10 | 1 table OR 1 figure (+ 1–2 supp.) |
+| Correspondence | 500–750 | — | (verify) | (verify) |
+| Special Article (AASLD guidelines, in-depth review, social policy) | ~5,000 (case-by-case) | (verify) | (verify) | (verify) |
+| Protocol Paper | 5,000 (excl. refs) | structured | (verify) | (verify) |
+| Consensus Report | 2,000 | — | 9 | (verify) |
+
+Title: ≤120 characters. Initial submission allowed in single Word file with text + artwork; revision must use 1.5 spacing, 10–12 pt body.
+
+## Abstract Requirements
+**Original Research:** 275 words, structured under exactly four headings: **Background**, **Methods**, **Results**, **Conclusion** (note: "Conclusion" singular, not "Conclusions"). Acronyms must be defined within the abstract. 5–7 keywords (preferably MeSH).
+
+## Required Sections (Original Article, in order)
+1. **Title page** (title, full author names with degrees + affiliations, financial support, conflicts, keywords, list of abbreviations)
+2. **Abstract** (275 words, 4-section structure)
+3. **Introduction** — minimum background, identify research gap
+4. **Methods** — sufficient for reproduction; reference statistical methods
+5. **Results** — present major findings, mention all tables/figures
+6. **Discussion** — implications; minimize repetition
+7. **Acknowledgements** — must include "Assistance with the study: none." or specifics; "Presentation: none." or meeting details
+8. **Disclosures** — financial support and competing interests (separate)
+9. **References** — AMA Manual of Style, Vancouver-numeric superscript
+10. **Tables** — separate Word docs, 1.5 spacing, vertical rules forbidden, abbreviations footnoted
+11. **Figure legends** — separate page after references; no embedded figures in main file
+12. **Supplemental Digital Content (SDC)** — optional; cited consecutively in main text; separate URL placement; PDF preferred
+
+## Statistical Reporting
+- Reference all statistical methods used; statistical software and version stated.
+- Uncertainty parameters mandatory in tables (95% CI, SD, IQR as appropriate).
+- AUROC diagrams must NOT be in main text — instead provide AUC (95% CI) inline; diagrams may go in supplement.
+- Sex/gender, race/ethnicity reporting per ICMJE — distinguish biological sex from gender identity.
+- Reporting checklists required: STROBE for observational, PRISMA for SR/MA, STARD for diagnostic accuracy, CONSORT for RCT, ARRIVE for animals, REMARK for tumor markers, SQUIRE for QI, COREQ for qualitative, IDEAL for surgical innovation, STREGA for genetic association, CHEERS for health economics.
+
+## Figures
+- Maximum 8 figures + tables combined.
+- Resolution: line art 1,200 dpi; halftone 300 dpi; combination halftone 600 dpi.
+- Format: EPS, TIFF, MS Office (DOC/PPT/XLS) for accepted manuscripts.
+- Composite figures: either single labelled image (Arial/Helvetica bold uppercase) or separate panels (Figure 1A.tif, Figure 1B.tif).
+- Color allowed (no extra charge given OA).
+- Figures must NOT be embedded in main body file (separate uploads).
+- Grayscale or RBG; do not embed legend text inside the image.
+
+## Common Rejection Reasons
+1. Failure to use 2023 MASLD/MASH nomenclature without justification ("Manuscripts ... should employ this revised terminology wherever scientifically appropriate" — explicit policy).
+2. Submitting AUROC diagrams in the main text (must move to supplement; AUC + 95% CI inline only).
+3. Tables with vertical rules or embedded images.
+4. Missing reporting-guideline checklist as supplement.
+5. Body of paper exceeds 5,000 words or > 50 references.
+6. Initial submission lacking ICMJE / Helsinki / Istanbul ethics statement in Methods (will be returned without review).
+
+## Cover Letter
+Should include:
+- Confirmation of originality and exclusivity (not under consideration elsewhere).
+- Explicit AI use disclosure if any (location and tool used) — mandatory in cover letter AND Methods.
+- Concept-origin statement (if idea originated outside corresponding/senior author).
+- Significance highlight tailored to AASLD readership.
+
+## AI Writing Disclosure Policy
+- **Requirement level:** Required (ICMJE-aligned).
+- **Permitted scope:** AI-assisted tools (LLMs, chatbots, image creators) used in writing, image production, or data analysis must be disclosed in the **Materials and Methods (or similar)** section AND in the **cover letter**, naming the tool and describing what it was used for. AI must not replace researcher responsibilities (analysis, interpretation, conclusions) and must not be listed as author or co-author. AI-generated material cannot be cited as a primary source.
+- **Disclosure location:** Materials and Methods + Cover Letter.
+- **Author responsibility:** Authors take full responsibility for AI-derived content including any breach of publication ethics.
+- **Policy URL:** https://edmgr.ovid.com/hepcomm/accounts/ifauth.htm (Authorship section)
+
+## Article Processing Charges (verified 2025 from PDF)
+| Article Type | AASLD Member | Non-Member |
+|---|---|---|
+| Tier 1 (Articles, Reviews, Experimental Research) | US$1,890 | US$3,150 |
+| Tier 2 (Letters, Editorials, Correspondence) | US$480 | US$800 |
+
+## Author Guidelines URL
+https://edmgr.ovid.com/hepcomm/accounts/ifauth.htm
+
+Editorial Office email: hepcomm@aasld.org
+Submission portal: https://mc.manuscriptcentral.com/hepcomm
+PaperPal Preflight: https://preflight.paperpal.com/partner/lww/hepatolcom
+
+## Positioning
+
+**When to submit here.** Korean / Asian / global health-screening cohort studies on MASLD natural history applying the 2023 nomenclature, retrospective hepatobiliary cohort analyses, MASLD-MASH translational research, biomarker validation papers, and AASLD-guideline-adherent clinical/translational work that did not make Hepatology's main journal cut. Particularly useful as the **OA fallback for the AASLD family** when authors want fast OA dissemination, prefer copyright retention, and have funder/institution OA mandates. Hepatology Communications also has a documented portable-peer-review pathway from Hepatology — manuscripts rejected at Hepatology can transfer with reviews intact.
+
+**When NOT to submit here.** Pure methodology/statistics papers without hepatology content. Studies that do not use 2023 MASLD nomenclature (will be flagged for revision unless justified). Manuscripts with > 50 refs or > 8 figures+tables that cannot be trimmed.
+
+| Dimension | Hepatology Communications | Hepatology (parent) | CMH (KASL) | Liver International |
+|---|---|---|---|---|
+| Society | AASLD (American) | AASLD | KASL | independent (Wiley) |
+| OA model | Mandatory full OA | Hybrid | Mandatory full OA | Hybrid |
+| APC (non-member) | US$3,150 | hybrid OA optional | US$1,500 | ~US$3,400 |
+| Acc. rate (est.) | ~30–35 % | ~10–15 % | ~25–30 % | ~20–25 % |
+| Word limit (Original) | 5,000 | 5,000 | 6,000 | 4,000 |
+| Graphical abstract | Optional | Optional | Mandatory | Optional |
+| 2023 MASLD nomenclature | Mandatory | Mandatory | Strong preference | Strong preference |

package/skills/write-paper/references/journal_profiles/Hepatology_International.md

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+# Journal Profile: Hepatology International
+
+## Journal Identity
+- **Full name:** Hepatology International
+- **Abbreviation:** Hepatol Int
+- **Publisher:** Springer Nature for APASL (Asian Pacific Association for the Study of the Liver)
+- **ISSN:** 1936-0533 (print) / 1936-0541 (online)
+- **Frequency:** Bimonthly
+- **Open Access:** Hybrid (Springer Open Choice optional; OA APC ~US$3,090, verify)
+- **Acceptance rate:** ~25–30 % (estimated; verify)
+- **Peer review:** Editorial Manager-based; copyright on accepted manuscripts is held by APASL.
+
+## Manuscript Types and Word Limits
+
+| Type | Body Word Limit | Abstract | References | Figures/Tables |
+|------|----------------|----------|------------|----------------|
+| Original Article | 4,000 (incl. refs) | 250 words structured | 30 | up to 6 (tables/flow diagrams/colored figures/text boxes) |
+| Review Article | 5,000 (incl. refs) | 250 words structured | 100 | ≥ 4 colored figures + ≥ 4 tables MANDATORY (total up to 8) |
+| Mini Review | 2,500 (excl. refs) | 150 words structured | 30 | ≥ 2 figures + ≥ 2 tables recommended (total up to 4) |
+| Invited Article (Editorial, by invitation) | 1,500 (excl. refs) | None | 10 | 1 figure |
+| Consensus | 2,000 | (verify) | 9 | (verify) |
+| Letter to Editor | 500 (excl. refs) | None | 5 | 1 figure |
+| Point-of-View (by invitation) | 1,500 (excl. refs) | None | 10 | 1 table + 2 figures |
+| Commentary (by invitation) | 1,500 (excl. refs) | None | 10 | 1 table + 1 figure |
+| Multimedia / Dynamic Article | per article type | per article type | per article type | up to 3 video clips, 1 min each (3 min for dynamic) |
+
+10 keywords mandated for all article types with abstracts.
+
+## Abstract Requirements
+**Original Article:** 250 words, structured (sub-headings not specified in publisher PDF — historically Background/Aims, Methods, Results, Conclusions). 10 keywords (not the typical 3–5).
+
+## Required Sections (Original Article, in order)
+1. **Title page** with **Compliance with Ethical Requirements** sub-section (CoI for each author, informed consent, human/animal rights statements)
+2. **Abstract** (250 words structured, 10 keywords)
+3. **Graphical Abstract** — single panel, **placed immediately after abstract**, MANDATORY for Original Articles
+4. **Introduction** (background and purpose)
+5. **Materials and Methods**
+6. **Results**
+7. **Discussion**
+8. **Declarations** (just before References — mandatory)
+   - Conflict of Interest and Ethical Standards
+   - Informed Consent
+   - Statement of Human and Animal Rights
+9. **References** (≤ 30 for Original)
+10. **Tables** / **Figures** / **Supplementary Information**
+
+## Statistical Reporting
+- General observational/clinical statistical conventions.
+- Reporting guideline citations expected (STROBE for cohort, PRISMA for SR/MA, STARD for diagnostic accuracy, ARRIVE for animals).
+- Springer's standard policy on data deposition / availability statement.
+- Sex/gender, race/ethnicity reporting per ICMJE.
+
+## Figures
+- **Graphical Abstract specifications (mandatory for Original Articles):**
+  - Single-panel image, 300 dpi+
+  - Format: .tif or .jpg preferred
+  - Font: Arial 12–16 pt
+  - Color: RGB
+  - Read direction: top-to-bottom or left-to-right
+  - Simple labels, bullet-form text
+  - Place next to abstract, labelled "Graphical Abstract"
+- Up to 6 illustrations (tables / flow diagrams / colored figures / text boxes / other) for Original Articles
+- Color figures supported (no extra charge; verify for hybrid OA workflow)
+- Permission required for any previously published figures, tables, or text passages
+
+## Common Rejection Reasons
+1. Missing graphical abstract on Original Article submission (will be returned).
+2. Word count > 4,000 (including references) for Original Article.
+3. Reference count > 30 for Original Article.
+4. Missing Compliance with Ethical Requirements sub-section on title page.
+5. Failure to upload signed Copyright/Authorship/Disclosure Form at submission.
+6. Sub-mission via incorrect Editorial Manager registration (re-registration breaks tracking).
+7. Errata requests submitted after proof approval (discouraged unless materially affecting interpretation).
+
+## Cover Letter
+Submission via Editorial Manager. Cover letter should:
+- Confirm originality and exclusivity (not under consideration elsewhere).
+- Highlight Asia-Pacific or APASL-guideline relevance where applicable.
+- Note any APASL meeting presentations.
+
+## AI Writing Disclosure Policy
+- **Requirement level:** Required (Springer Nature follows ICMJE).
+- **Permitted scope:** AI use must be disclosed; AI cannot be author. (Springer Nature's general policy applies; verify journal-specific addendum.)
+- **Disclosure location:** Acknowledgements / Methods.
+- **Policy URL:** https://www.springernature.com/gp/policies/editorial-policies (parent policy)
+
+## Author Guidelines URL
+https://link.springer.com/journal/12072/submission-guidelines
+
+Editorial Manager: https://www.editorialmanager.com/heip
+Copyright/Authorship/Disclosure Form: downloadable from Editorial Manager submission page (mandatory)
+
+## Positioning
+
+**When to submit here.** Asian-Pacific cohort hepatology, MASLD/NAFLD natural history in East-Asian populations, lean MASLD, chronic hepatitis B (regional endemic), HCC surveillance, and APASL-guideline-relevant clinical work. Korean and Japanese MASLD cohort studies are well-represented. Strong fit when Asia-Pacific generalizability is the headline contribution. Mandatory graphical abstract is a real constraint — design it before drafting because it will be the first thing editors see.
+
+**When NOT to submit here.** Pure methodology papers without hepatology content. Studies on non-hepatobiliary primary outcomes. Manuscripts unwilling or unable to produce a graphical abstract. Time-pressed submissions — Editorial Manager registration can be slow.
+
+| Dimension | Hepatology International | Hepatol Communications | CMH (KASL) | Liver International |
+|---|---|---|---|---|
+| Society | APASL (Asia-Pacific) | AASLD (American) | KASL (Korean) | independent (Wiley) |
+| OA model | Hybrid | Mandatory OA | Mandatory OA | Hybrid |
+| Original word limit | 4,000 (incl. refs) | 5,000 (excl. refs) | 6,000 (incl. refs/figs) | 4,000 (excl. refs) |
+| Graphical abstract | **Mandatory** | Optional | **Mandatory** | Optional |
+| Reference cap | 30 | 50 | 50 | 60 |
+| Korean cohort fit | High | Moderate-High | Highest | High |