@oriro/orirocli 0.1.11 → 0.1.12

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (1263) hide show
  1. package/ATTRIBUTION.md +53 -53
  2. package/LICENSE +21 -21
  3. package/README.md +2 -7
  4. package/dist/cli.js +402 -40
  5. package/package.json +64 -64
  6. package/skills/1password/SKILL.md +118 -118
  7. package/skills/1password/references/cli-examples.md +29 -29
  8. package/skills/1password/references/get-started.md +21 -21
  9. package/skills/21stdev/SKILL.md +64 -64
  10. package/skills/algorithmic-art/LICENSE +21 -21
  11. package/skills/algorithmic-art/SKILL.md +446 -446
  12. package/skills/algorithmic-art/templates/generator_template.js +223 -223
  13. package/skills/algorithmic-art/templates/viewer.html +598 -598
  14. package/skills/apple-notes/SKILL.md +81 -81
  15. package/skills/apple-reminders/SKILL.md +122 -122
  16. package/skills/bear-notes/SKILL.md +111 -111
  17. package/skills/blogwatcher/SKILL.md +73 -73
  18. package/skills/blucli/SKILL.md +51 -51
  19. package/skills/brand-guidelines/LICENSE +21 -21
  20. package/skills/brand-guidelines/SKILL.md +76 -76
  21. package/skills/business/biz-analysis/LICENSE +21 -21
  22. package/skills/business/biz-analysis/SKILL.md +103 -103
  23. package/skills/business/biz-corporate-strategy/LICENSE +21 -21
  24. package/skills/business/biz-corporate-strategy/SKILL.md +76 -76
  25. package/skills/business/biz-customer-success/LICENSE +21 -21
  26. package/skills/business/biz-customer-success/SKILL.md +55 -55
  27. package/skills/business/biz-entrepreneurship/LICENSE +21 -21
  28. package/skills/business/biz-entrepreneurship/SKILL.md +72 -72
  29. package/skills/business/biz-hr/LICENSE +21 -21
  30. package/skills/business/biz-hr/SKILL.md +67 -67
  31. package/skills/business/biz-international/LICENSE +21 -21
  32. package/skills/business/biz-international/SKILL.md +51 -51
  33. package/skills/business/biz-leadership/LICENSE +21 -21
  34. package/skills/business/biz-leadership/SKILL.md +106 -106
  35. package/skills/business/biz-marketing-strategy/LICENSE +21 -21
  36. package/skills/business/biz-marketing-strategy/SKILL.md +119 -119
  37. package/skills/business/biz-negotiation/LICENSE +21 -21
  38. package/skills/business/biz-negotiation/SKILL.md +152 -152
  39. package/skills/business/biz-operations/LICENSE +21 -21
  40. package/skills/business/biz-operations/SKILL.md +74 -74
  41. package/skills/business/biz-project/LICENSE +21 -21
  42. package/skills/business/biz-project/SKILL.md +203 -203
  43. package/skills/business/biz-risk/LICENSE +21 -21
  44. package/skills/business/biz-risk/SKILL.md +85 -85
  45. package/skills/business/biz-sales/LICENSE +21 -21
  46. package/skills/business/biz-sales/SKILL.md +92 -92
  47. package/skills/business/biz-startup-ops/LICENSE +21 -21
  48. package/skills/business/biz-startup-ops/SKILL.md +70 -70
  49. package/skills/business/biz-strategy/LICENSE +21 -21
  50. package/skills/business/biz-strategy/SKILL.md +233 -233
  51. package/skills/business/biz-supply-chain-advanced/LICENSE +21 -21
  52. package/skills/business/biz-supply-chain-advanced/SKILL.md +68 -68
  53. package/skills/business/fin-chartered-exams/LICENSE +21 -21
  54. package/skills/business/fin-chartered-exams/SKILL.md +69 -69
  55. package/skills/camsnap/SKILL.md +49 -49
  56. package/skills/canvas/SKILL.md +82 -82
  57. package/skills/canvas-design/LICENSE +21 -21
  58. package/skills/canvas-design/SKILL.md +140 -140
  59. package/skills/canvas-design/canvas-fonts/ArsenalSC-OFL.txt +93 -93
  60. package/skills/canvas-design/canvas-fonts/BigShoulders-OFL.txt +93 -93
  61. package/skills/canvas-design/canvas-fonts/Boldonse-OFL.txt +93 -93
  62. package/skills/canvas-design/canvas-fonts/BricolageGrotesque-OFL.txt +93 -93
  63. package/skills/canvas-design/canvas-fonts/CrimsonPro-OFL.txt +93 -93
  64. package/skills/canvas-design/canvas-fonts/DMMono-OFL.txt +93 -93
  65. package/skills/canvas-design/canvas-fonts/EricaOne-OFL.txt +94 -94
  66. package/skills/canvas-design/canvas-fonts/GeistMono-OFL.txt +93 -93
  67. package/skills/canvas-design/canvas-fonts/Gloock-OFL.txt +93 -93
  68. package/skills/canvas-design/canvas-fonts/IBMPlexMono-OFL.txt +93 -93
  69. package/skills/canvas-design/canvas-fonts/InstrumentSans-OFL.txt +93 -93
  70. package/skills/canvas-design/canvas-fonts/JetBrainsMono-OFL.txt +93 -93
  71. package/skills/canvas-design/canvas-fonts/Jura-OFL.txt +93 -93
  72. package/skills/canvas-design/canvas-fonts/LibreBaskerville-OFL.txt +93 -93
  73. package/skills/canvas-design/canvas-fonts/Lora-OFL.txt +93 -93
  74. package/skills/canvas-design/canvas-fonts/NationalPark-OFL.txt +93 -93
  75. package/skills/canvas-design/canvas-fonts/Outfit-OFL.txt +93 -93
  76. package/skills/canvas-design/canvas-fonts/PixelifySans-OFL.txt +93 -93
  77. package/skills/canvas-design/canvas-fonts/RedHatMono-OFL.txt +93 -93
  78. package/skills/canvas-design/canvas-fonts/Silkscreen-OFL.txt +93 -93
  79. package/skills/canvas-design/canvas-fonts/SmoochSans-OFL.txt +93 -93
  80. package/skills/canvas-design/canvas-fonts/Tektur-OFL.txt +93 -93
  81. package/skills/canvas-design/canvas-fonts/WorkSans-OFL.txt +93 -93
  82. package/skills/canvas-design/canvas-fonts/YoungSerif-OFL.txt +93 -93
  83. package/skills/coding-agent/SKILL.md +146 -146
  84. package/skills/communication/comm-business-writing/LICENSE +21 -21
  85. package/skills/communication/comm-business-writing/SKILL.md +67 -67
  86. package/skills/communication/comm-cross-cultural/LICENSE +21 -21
  87. package/skills/communication/comm-cross-cultural/SKILL.md +88 -88
  88. package/skills/communication/comm-journalism/LICENSE +21 -21
  89. package/skills/communication/comm-journalism/SKILL.md +81 -81
  90. package/skills/communication/comm-linguistics/LICENSE +21 -21
  91. package/skills/communication/comm-linguistics/SKILL.md +82 -82
  92. package/skills/communication/comm-negotiation/LICENSE +21 -21
  93. package/skills/communication/comm-negotiation/SKILL.md +120 -120
  94. package/skills/communication/comm-presentations/LICENSE +21 -21
  95. package/skills/communication/comm-presentations/SKILL.md +93 -93
  96. package/skills/communication/comm-public-speaking/LICENSE +21 -21
  97. package/skills/communication/comm-public-speaking/SKILL.md +68 -68
  98. package/skills/communication/comm-writing/LICENSE +21 -21
  99. package/skills/communication/comm-writing/SKILL.md +69 -69
  100. package/skills/craft/ai-engineering/LICENSE +21 -21
  101. package/skills/craft/ai-engineering/SKILL.md +828 -828
  102. package/skills/craft/app-builder-guide/LICENSE +21 -21
  103. package/skills/craft/app-builder-guide/SKILL.md +332 -332
  104. package/skills/craft/become-an-ai-engineer-26/CONTRIBUTING.md +46 -46
  105. package/skills/craft/become-an-ai-engineer-26/LICENSE +21 -21
  106. package/skills/craft/become-an-ai-engineer-26/README.md +270 -270
  107. package/skills/craft/become-an-ai-engineer-26/SKILL.md +667 -667
  108. package/skills/craft/become-an-ai-engineer-26/community/BUILDS.md +13 -13
  109. package/skills/craft/become-an-ai-engineer-26/community/DISCUSSIONS.md +8 -8
  110. package/skills/craft/become-an-ai-engineer-26/phases/phase-0-mental-models/README.md +14 -14
  111. package/skills/craft/become-an-ai-engineer-26/phases/phase-0-mental-models/project/TEMPLATE.md +33 -33
  112. package/skills/craft/become-an-ai-engineer-26/phases/phase-1-first-agent/README.md +25 -25
  113. package/skills/craft/become-an-ai-engineer-26/phases/phase-1-first-agent/code/raw_loop.py +126 -126
  114. package/skills/craft/become-an-ai-engineer-26/phases/phase-2-architecture/README.md +17 -17
  115. package/skills/craft/become-an-ai-engineer-26/phases/phase-3-harness/README.md +17 -17
  116. package/skills/craft/become-an-ai-engineer-26/phases/phase-4-evals/README.md +21 -21
  117. package/skills/craft/become-an-ai-engineer-26/phases/phase-4-evals/code/.github/workflows/eval.yml +40 -40
  118. package/skills/craft/become-an-ai-engineer-26/phases/phase-5-production/README.md +16 -16
  119. package/skills/craft/become-an-ai-engineer-26/projects/1-mobile-app-slm/README.md +11 -11
  120. package/skills/craft/become-an-ai-engineer-26/projects/2-self-improving-coder/README.md +11 -11
  121. package/skills/craft/become-an-ai-engineer-26/projects/3-video-editor-agent/README.md +11 -11
  122. package/skills/craft/become-an-ai-engineer-26/projects/4-personal-life-os/README.md +12 -12
  123. package/skills/craft/become-an-ai-engineer-26/projects/5-enterprise-workflow/README.md +12 -12
  124. package/skills/craft/become-an-ai-engineer-26/references/benchmark-numbers.md +41 -41
  125. package/skills/craft/become-an-ai-engineer-26/references/mhc-stable-training.md +73 -73
  126. package/skills/craft/become-an-ai-engineer-26/references/stack-decisions.md +37 -37
  127. package/skills/craft/become-an-ai-engineer-26/references/yarn-context-extension.md +123 -123
  128. package/skills/craft/codex-result-handling/LICENSE +21 -21
  129. package/skills/craft/codex-result-handling/SKILL.md +26 -26
  130. package/skills/craft/debug-and-build-methodology/LICENSE +21 -21
  131. package/skills/craft/debug-and-build-methodology/SKILL.md +432 -432
  132. package/skills/craft/design/LICENSE +21 -21
  133. package/skills/craft/design/SKILL.md +274 -274
  134. package/skills/craft/dev/LICENSE +21 -21
  135. package/skills/craft/dev/SKILL.md +12 -12
  136. package/skills/craft/dev/release.md +85 -85
  137. package/skills/craft/dev/roll.md +50 -50
  138. package/skills/craft/doc-coauthoring/LICENSE +21 -21
  139. package/skills/craft/doc-coauthoring/SKILL.md +397 -397
  140. package/skills/craft/focus/LICENSE +21 -21
  141. package/skills/craft/focus/SKILL.md +432 -432
  142. package/skills/craft/focus/UPSTREAM_README.md +233 -233
  143. package/skills/craft/gh/LICENSE +21 -21
  144. package/skills/craft/gh/SKILL.md +84 -84
  145. package/skills/craft/gh-skill/LICENSE +21 -21
  146. package/skills/craft/gh-skill/SKILL.md +121 -121
  147. package/skills/craft/godmode/LICENSE +21 -21
  148. package/skills/craft/godmode/SKILL.md +87 -87
  149. package/skills/craft/godmode/references/android-launch.md +680 -680
  150. package/skills/craft/godmode/references/data-gcp.md +1038 -1038
  151. package/skills/craft/godmode/references/expo-eas.md +816 -816
  152. package/skills/craft/godmode/references/ios-launch.md +734 -734
  153. package/skills/craft/google-ai-latest/LICENSE +21 -21
  154. package/skills/craft/google-ai-latest/SKILL.md +682 -682
  155. package/skills/craft/gpt-5-4-prompting/LICENSE +21 -21
  156. package/skills/craft/gpt-5-4-prompting/SKILL.md +63 -63
  157. package/skills/craft/gpt-5-4-prompting/references/codex-prompt-antipatterns.md +101 -101
  158. package/skills/craft/gpt-5-4-prompting/references/codex-prompt-recipes.md +150 -150
  159. package/skills/craft/gpt-5-4-prompting/references/prompt-blocks.md +172 -172
  160. package/skills/craft/grill-me/LICENSE +21 -21
  161. package/skills/craft/grill-me/SKILL.md +13 -13
  162. package/skills/craft/idea-to-deploy/LICENSE +21 -21
  163. package/skills/craft/idea-to-deploy/SKILL.md +292 -292
  164. package/skills/craft/idea-to-deploy/references/auth-playbook.md +195 -195
  165. package/skills/craft/idea-to-deploy/references/gcp-deployment.md +268 -268
  166. package/skills/craft/idea-to-deploy/references/stack-selection.md +117 -117
  167. package/skills/craft/image-generation-engineer/LICENSE +21 -21
  168. package/skills/craft/image-generation-engineer/SKILL.md +183 -183
  169. package/skills/craft/image-generation-engineer/references/architectures.md +260 -260
  170. package/skills/craft/image-generation-engineer/references/foundations.md +107 -107
  171. package/skills/craft/image-generation-engineer/references/inference-and-serving.md +253 -253
  172. package/skills/craft/image-generation-engineer/references/training.md +149 -149
  173. package/skills/craft/marketing/LICENSE +21 -21
  174. package/skills/craft/marketing/SKILL.md +1954 -1954
  175. package/skills/craft/master-architect/LICENSE +21 -21
  176. package/skills/craft/master-architect/SKILL.md +361 -361
  177. package/skills/craft/master-architect/references/ai-ml.md +317 -317
  178. package/skills/craft/master-architect/references/architecture.md +268 -268
  179. package/skills/craft/master-architect/references/auth-playbook.md +195 -195
  180. package/skills/craft/master-architect/references/cloud.md +323 -323
  181. package/skills/craft/master-architect/references/cyber.md +839 -839
  182. package/skills/craft/master-architect/references/data-eng.md +366 -366
  183. package/skills/craft/master-architect/references/devops.md +550 -550
  184. package/skills/craft/master-architect/references/gcp-deployment.md +268 -268
  185. package/skills/craft/master-architect/references/languages.md +748 -748
  186. package/skills/craft/master-architect/references/legacy.md +240 -240
  187. package/skills/craft/master-architect/references/mobile.md +447 -447
  188. package/skills/craft/master-architect/references/patterns.md +451 -451
  189. package/skills/craft/master-architect/references/saas-patterns.md +379 -379
  190. package/skills/craft/master-architect/references/sdlc.md +349 -349
  191. package/skills/craft/master-architect/references/stack-selection.md +117 -117
  192. package/skills/craft/oriro-ui-2026/LICENSE +21 -21
  193. package/skills/craft/oriro-ui-2026/SKILL.md +329 -329
  194. package/skills/craft/playwright-cli/LICENSE +21 -21
  195. package/skills/craft/playwright-cli/SKILL.md +393 -393
  196. package/skills/craft/playwright-cli/references/element-attributes.md +23 -23
  197. package/skills/craft/playwright-cli/references/playwright-tests.md +39 -39
  198. package/skills/craft/playwright-cli/references/request-mocking.md +87 -87
  199. package/skills/craft/playwright-cli/references/running-code.md +240 -240
  200. package/skills/craft/playwright-cli/references/session-management.md +226 -226
  201. package/skills/craft/playwright-cli/references/spec-driven-testing.md +312 -312
  202. package/skills/craft/playwright-cli/references/storage-state.md +275 -275
  203. package/skills/craft/playwright-cli/references/test-generation.md +134 -134
  204. package/skills/craft/playwright-cli/references/tracing.md +142 -142
  205. package/skills/craft/playwright-cli/references/video-recording.md +150 -150
  206. package/skills/craft/remotion-best-practices/LICENSE +21 -21
  207. package/skills/craft/remotion-best-practices/SKILL.md +345 -345
  208. package/skills/craft/remotion-best-practices/rules/3d.md +86 -86
  209. package/skills/craft/remotion-best-practices/rules/assets/charts-bar-chart.tsx +165 -165
  210. package/skills/craft/remotion-best-practices/rules/assets/text-animations-typewriter.tsx +89 -89
  211. package/skills/craft/remotion-best-practices/rules/assets/text-animations-word-highlight.tsx +101 -101
  212. package/skills/craft/remotion-best-practices/rules/audio-visualization.md +195 -195
  213. package/skills/craft/remotion-best-practices/rules/audio.md +167 -167
  214. package/skills/craft/remotion-best-practices/rules/calculate-metadata.md +118 -118
  215. package/skills/craft/remotion-best-practices/rules/compositions.md +132 -132
  216. package/skills/craft/remotion-best-practices/rules/display-captions.md +176 -176
  217. package/skills/craft/remotion-best-practices/rules/ffmpeg.md +34 -34
  218. package/skills/craft/remotion-best-practices/rules/get-audio-duration.md +58 -58
  219. package/skills/craft/remotion-best-practices/rules/get-video-dimensions.md +68 -68
  220. package/skills/craft/remotion-best-practices/rules/get-video-duration.md +60 -60
  221. package/skills/craft/remotion-best-practices/rules/gifs.md +135 -135
  222. package/skills/craft/remotion-best-practices/rules/google-fonts.md +72 -72
  223. package/skills/craft/remotion-best-practices/rules/html-in-canvas.md +122 -122
  224. package/skills/craft/remotion-best-practices/rules/images.md +67 -67
  225. package/skills/craft/remotion-best-practices/rules/import-srt-captions.md +69 -69
  226. package/skills/craft/remotion-best-practices/rules/light-leaks.md +73 -73
  227. package/skills/craft/remotion-best-practices/rules/local-fonts.md +65 -65
  228. package/skills/craft/remotion-best-practices/rules/lottie.md +67 -67
  229. package/skills/craft/remotion-best-practices/rules/maplibre.md +441 -441
  230. package/skills/craft/remotion-best-practices/rules/measuring-dom-nodes.md +34 -34
  231. package/skills/craft/remotion-best-practices/rules/measuring-text.md +140 -140
  232. package/skills/craft/remotion-best-practices/rules/parameters.md +109 -109
  233. package/skills/craft/remotion-best-practices/rules/sequencing.md +144 -144
  234. package/skills/craft/remotion-best-practices/rules/sfx.md +30 -30
  235. package/skills/craft/remotion-best-practices/rules/silence-detection.md +73 -73
  236. package/skills/craft/remotion-best-practices/rules/subtitles.md +36 -36
  237. package/skills/craft/remotion-best-practices/rules/tailwind.md +11 -11
  238. package/skills/craft/remotion-best-practices/rules/text-animations.md +20 -20
  239. package/skills/craft/remotion-best-practices/rules/timing.md +130 -130
  240. package/skills/craft/remotion-best-practices/rules/transcribe-captions.md +70 -70
  241. package/skills/craft/remotion-best-practices/rules/transitions.md +193 -193
  242. package/skills/craft/remotion-best-practices/rules/transparent-videos.md +102 -102
  243. package/skills/craft/remotion-best-practices/rules/trimming.md +51 -51
  244. package/skills/craft/remotion-best-practices/rules/videos.md +169 -169
  245. package/skills/craft/remotion-best-practices/rules/voiceover.md +94 -94
  246. package/skills/craft/supabase-postgres-best-practices/CHANGELOG.md +25 -25
  247. package/skills/craft/supabase-postgres-best-practices/LICENSE +21 -21
  248. package/skills/craft/supabase-postgres-best-practices/SKILL.md +69 -69
  249. package/skills/craft/supabase-postgres-best-practices/references/_contributing.md +166 -166
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  251. package/skills/craft/supabase-postgres-best-practices/references/_template.md +34 -34
  252. package/skills/craft/supabase-postgres-best-practices/references/advanced-full-text-search.md +55 -55
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  256. package/skills/craft/supabase-postgres-best-practices/references/conn-pooling.md +41 -41
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  258. package/skills/craft/supabase-postgres-best-practices/references/data-batch-inserts.md +54 -54
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  261. package/skills/craft/supabase-postgres-best-practices/references/data-upsert.md +50 -50
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  263. package/skills/craft/supabase-postgres-best-practices/references/lock-deadlock-prevention.md +68 -68
  264. package/skills/craft/supabase-postgres-best-practices/references/lock-short-transactions.md +50 -50
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  267. package/skills/craft/supabase-postgres-best-practices/references/monitor-pg-stat-statements.md +55 -55
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  270. package/skills/craft/supabase-postgres-best-practices/references/query-covering-indexes.md +40 -40
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  273. package/skills/craft/supabase-postgres-best-practices/references/query-partial-indexes.md +45 -45
  274. package/skills/craft/supabase-postgres-best-practices/references/schema-constraints.md +80 -80
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  1263. package/skills/graphify/wiki.py +0 -282
@@ -1,82 +1,82 @@
1
- ---
2
- watermark: ORIRO
3
- disable-model-invocation: true
4
- name: health-aging
5
- provider: ORIRO.ai
6
- copyright: Copyright (c) 2026 ORIRO.ai
7
- description: >
8
-
9
-
10
- Aging and elder care — age-related health changes, fall prevention, cognitive health, polypharmacy, caregiver guidance, and end-of-life planning. Sources: NIA, CDC healthy aging, AGS geriatric guidelines.
11
- Consult your healthcare provider for personal medical guidance.
12
- ---
13
-
14
- # Aging and Elder Care
15
-
16
- ## Normal physiological changes with aging
17
-
18
- **Cardiovascular:** Decreased maximum heart rate, reduced cardiac reserve, increased vascular stiffness, BP tends to rise.
19
- **Musculoskeletal:** Sarcopenia (muscle loss) — ~1-2% per year after 50. Bone density decreases. Joint changes.
20
- **Cognitive:** Normal: slower processing speed, slight memory lag (tip of tongue), easier fatigue. NOT normal: getting lost in familiar places, forgetting recent events repeatedly, personality changes.
21
- **Sensory:** Presbyopia (reading glasses needed), presbycusis (high-frequency hearing loss), reduced taste/smell.
22
- **Sleep:** Earlier sleep phase, more fragmented, less deep sleep. Total hours similar but more interrupted.
23
- **Immune:** Immunosenescence — slower immune response, reduced vaccine efficacy, higher infection risk.
24
- **Renal/Hepatic:** Reduced kidney and liver function → drugs clear more slowly → dose adjustments needed.
25
-
26
- ## Polypharmacy
27
-
28
- Using 5+ medications simultaneously (common in adults 65+; average is 8+).
29
- **Problems:** Drug interactions, falls risk, adverse effects, cognitive effects, adherence challenges.
30
- **Beers Criteria** (AGS): List of medications potentially inappropriate for older adults:
31
-
32
- - Benzodiazepines: fall/cognitive risk
33
- - First-generation antihistamines (diphenhydramine/Benadryl): anticholinergic, confusion, falls
34
- - Long-acting sulfonylureas (glipizide extended release): hypoglycemia
35
- - NSAIDs (long-term): GI bleeding, renal impairment, BP effects
36
- - Muscle relaxants (cyclobenzaprine): sedation, falls
37
- **Medication review:** Ask doctor annually to review all medications for continued necessity.
38
-
39
- ## Fall prevention — most important safety intervention
40
-
41
- Falls cause 36 million injuries/year in US older adults. 32,000 deaths annually.
42
- **Risk factors:** Prior fall, muscle weakness, balance problems, home hazards, polypharmacy, vision problems.
43
- **Prevention:**
44
-
45
- - Exercise: Tai chi, balance training, strength training all proven to reduce falls
46
- - Medication review: Reduce fall-risk medications
47
- - Home modification: Remove throw rugs, add grab bars, improve lighting
48
- - Vision check annually: Poor vision ↑ fall risk significantly
49
- - Vitamin D: 800-1000 IU/day reduces falls in deficient older adults
50
-
51
- ## Cognitive health
52
-
53
- **Normal aging vs. MCI vs. Dementia:**
54
- Normal: Occasional word-finding, slower recall — doesn't interfere with daily function.
55
- MCI (Mild Cognitive Impairment): Noticeable cognitive change beyond normal, but still independent.
56
- Dementia: Cognitive decline that impairs daily functioning.
57
-
58
- **Alzheimer's warning signs (Alzheimer's Association):**
59
- Memory loss disrupting daily life, challenges with planning, familiar tasks become difficult, confusion with time/place, new visual problems, word-finding problems, misplacing items unable to retrace, poor judgment, withdrawal, personality/mood changes.
60
-
61
- **Risk reduction (evidence-based):**
62
- Physical exercise (strongest evidence), cognitively stimulating activities, social engagement, treating hearing loss (significant risk modifier), controlling vascular risk factors (hypertension, diabetes, cholesterol), sleep quality.
63
-
64
- **Mediterranean diet / MIND diet:** Associated with lower dementia risk in observational studies.
65
-
66
- ## Caregiver guidance
67
-
68
- Caregiver burden is real — 40% of Alzheimer's caregivers develop depression.
69
- **Resources:** Alzheimer's Association 24/7 helpline: 800-272-3900
70
- **Respite care:** Temporary relief for caregivers. Adult day programs, in-home respite, short-term residential care.
71
- **Legal planning early:** Power of Attorney (financial), Healthcare Proxy, advance directive — do while person has capacity.
72
-
73
- ## Advance directives
74
-
75
- **Living will:** Documents preferences for end-of-life care.
76
- **Healthcare proxy / DPOA for healthcare:** Designates someone to make medical decisions if unable.
77
- **POLST/MOLST:** (Physician Orders for Life-Sustaining Treatment) Portable medical order for patients with serious illness.
78
- **DNR/DNI:** Do Not Resuscitate / Do Not Intubate — medical orders, not just expressed wishes.
79
-
80
- Complete these documents while healthy. Review periodically. Provide copies to family, physicians, hospital.
81
-
82
- Sources: National Institute on Aging (nia.nih.gov), CDC Healthy Aging (cdc.gov), AGS Beers Criteria (americangeriatrics.org), Alzheimer's Association (alz.org)
1
+ ---
2
+ watermark: ORIRO
3
+ disable-model-invocation: true
4
+ name: health-aging
5
+ provider: ORIRO.ai
6
+ copyright: Copyright (c) 2026 ORIRO.ai
7
+ description: >
8
+
9
+
10
+ Aging and elder care — age-related health changes, fall prevention, cognitive health, polypharmacy, caregiver guidance, and end-of-life planning. Sources: NIA, CDC healthy aging, AGS geriatric guidelines.
11
+ Consult your healthcare provider for personal medical guidance.
12
+ ---
13
+
14
+ # Aging and Elder Care
15
+
16
+ ## Normal physiological changes with aging
17
+
18
+ **Cardiovascular:** Decreased maximum heart rate, reduced cardiac reserve, increased vascular stiffness, BP tends to rise.
19
+ **Musculoskeletal:** Sarcopenia (muscle loss) — ~1-2% per year after 50. Bone density decreases. Joint changes.
20
+ **Cognitive:** Normal: slower processing speed, slight memory lag (tip of tongue), easier fatigue. NOT normal: getting lost in familiar places, forgetting recent events repeatedly, personality changes.
21
+ **Sensory:** Presbyopia (reading glasses needed), presbycusis (high-frequency hearing loss), reduced taste/smell.
22
+ **Sleep:** Earlier sleep phase, more fragmented, less deep sleep. Total hours similar but more interrupted.
23
+ **Immune:** Immunosenescence — slower immune response, reduced vaccine efficacy, higher infection risk.
24
+ **Renal/Hepatic:** Reduced kidney and liver function → drugs clear more slowly → dose adjustments needed.
25
+
26
+ ## Polypharmacy
27
+
28
+ Using 5+ medications simultaneously (common in adults 65+; average is 8+).
29
+ **Problems:** Drug interactions, falls risk, adverse effects, cognitive effects, adherence challenges.
30
+ **Beers Criteria** (AGS): List of medications potentially inappropriate for older adults:
31
+
32
+ - Benzodiazepines: fall/cognitive risk
33
+ - First-generation antihistamines (diphenhydramine/Benadryl): anticholinergic, confusion, falls
34
+ - Long-acting sulfonylureas (glipizide extended release): hypoglycemia
35
+ - NSAIDs (long-term): GI bleeding, renal impairment, BP effects
36
+ - Muscle relaxants (cyclobenzaprine): sedation, falls
37
+ **Medication review:** Ask doctor annually to review all medications for continued necessity.
38
+
39
+ ## Fall prevention — most important safety intervention
40
+
41
+ Falls cause 36 million injuries/year in US older adults. 32,000 deaths annually.
42
+ **Risk factors:** Prior fall, muscle weakness, balance problems, home hazards, polypharmacy, vision problems.
43
+ **Prevention:**
44
+
45
+ - Exercise: Tai chi, balance training, strength training all proven to reduce falls
46
+ - Medication review: Reduce fall-risk medications
47
+ - Home modification: Remove throw rugs, add grab bars, improve lighting
48
+ - Vision check annually: Poor vision ↑ fall risk significantly
49
+ - Vitamin D: 800-1000 IU/day reduces falls in deficient older adults
50
+
51
+ ## Cognitive health
52
+
53
+ **Normal aging vs. MCI vs. Dementia:**
54
+ Normal: Occasional word-finding, slower recall — doesn't interfere with daily function.
55
+ MCI (Mild Cognitive Impairment): Noticeable cognitive change beyond normal, but still independent.
56
+ Dementia: Cognitive decline that impairs daily functioning.
57
+
58
+ **Alzheimer's warning signs (Alzheimer's Association):**
59
+ Memory loss disrupting daily life, challenges with planning, familiar tasks become difficult, confusion with time/place, new visual problems, word-finding problems, misplacing items unable to retrace, poor judgment, withdrawal, personality/mood changes.
60
+
61
+ **Risk reduction (evidence-based):**
62
+ Physical exercise (strongest evidence), cognitively stimulating activities, social engagement, treating hearing loss (significant risk modifier), controlling vascular risk factors (hypertension, diabetes, cholesterol), sleep quality.
63
+
64
+ **Mediterranean diet / MIND diet:** Associated with lower dementia risk in observational studies.
65
+
66
+ ## Caregiver guidance
67
+
68
+ Caregiver burden is real — 40% of Alzheimer's caregivers develop depression.
69
+ **Resources:** Alzheimer's Association 24/7 helpline: 800-272-3900
70
+ **Respite care:** Temporary relief for caregivers. Adult day programs, in-home respite, short-term residential care.
71
+ **Legal planning early:** Power of Attorney (financial), Healthcare Proxy, advance directive — do while person has capacity.
72
+
73
+ ## Advance directives
74
+
75
+ **Living will:** Documents preferences for end-of-life care.
76
+ **Healthcare proxy / DPOA for healthcare:** Designates someone to make medical decisions if unable.
77
+ **POLST/MOLST:** (Physician Orders for Life-Sustaining Treatment) Portable medical order for patients with serious illness.
78
+ **DNR/DNI:** Do Not Resuscitate / Do Not Intubate — medical orders, not just expressed wishes.
79
+
80
+ Complete these documents while healthy. Review periodically. Provide copies to family, physicians, hospital.
81
+
82
+ Sources: National Institute on Aging (nia.nih.gov), CDC Healthy Aging (cdc.gov), AGS Beers Criteria (americangeriatrics.org), Alzheimer's Association (alz.org)
@@ -1,21 +1,21 @@
1
- MIT License
2
-
3
- Copyright (c) 2026 ORIRO.ai
4
-
5
- Permission is hereby granted, free of charge, to any person obtaining a copy
6
- of this software and associated documentation files (the "Software"), to deal
7
- in the Software without restriction, including without limitation the rights
8
- to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
9
- copies of the Software, and to permit persons to whom the Software is
10
- furnished to do so, subject to the following conditions:
11
-
12
- The above copyright notice and this permission notice shall be included in all
13
- copies or substantial portions of the Software.
14
-
15
- THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
16
- IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
17
- FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
18
- AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
19
- LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
20
- OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
21
- SOFTWARE.
1
+ MIT License
2
+
3
+ Copyright (c) 2026 ORIRO.ai
4
+
5
+ Permission is hereby granted, free of charge, to any person obtaining a copy
6
+ of this software and associated documentation files (the "Software"), to deal
7
+ in the Software without restriction, including without limitation the rights
8
+ to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
9
+ copies of the Software, and to permit persons to whom the Software is
10
+ furnished to do so, subject to the following conditions:
11
+
12
+ The above copyright notice and this permission notice shall be included in all
13
+ copies or substantial portions of the Software.
14
+
15
+ THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
16
+ IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
17
+ FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
18
+ AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
19
+ LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
20
+ OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
21
+ SOFTWARE.
@@ -1,202 +1,202 @@
1
- ---
2
- watermark: ORIRO
3
- disable-model-invocation: true
4
- name: health-chronic
5
- provider: ORIRO.ai
6
- copyright: Copyright (c) 2026 ORIRO.ai
7
- description: >
8
- Chronic disease management — diabetes, hypertension, heart disease, asthma,
9
- COPD, arthritis. Activate for questions about managing chronic conditions,
10
- understanding treatment plans, lifestyle modifications, monitoring, or
11
- any chronic disease management question. Sources: ADA, ACC/AHA guidelines,
12
- CDC chronic disease resources, NHLBI. Always work with your healthcare team.
13
- ---
14
-
15
- # Chronic Disease Management
16
-
17
- ## Diabetes
18
-
19
- ### Type 1 vs. Type 2
20
-
21
- **Type 1:** Autoimmune destruction of beta cells. No insulin production. Requires insulin for survival.
22
- **Type 2:** Insulin resistance + declining beta cell function. Progressive. Most common form (90-95%).
23
- **Prediabetes:** Fasting glucose 100-125 mg/dL or A1C 5.7-6.4%. Reversible with lifestyle.
24
-
25
- ### Blood sugar targets (ADA guidelines)
26
-
27
- - Fasting/pre-meal: 80-130 mg/dL
28
- - 2 hours after meals: < 180 mg/dL
29
- - A1C: < 7% for most adults (less stringent for elderly/complex)
30
-
31
- ### Type 2 management hierarchy
32
-
33
- 1. **Lifestyle first:** Weight loss (even 5-10% significantly improves glucose), exercise, diet.
34
- 2. **Metformin:** First-line medication. Cheap, effective, well-tolerated. Take with food.
35
- 3. **Add-on medications:** GLP-1 agonists (semaglutide, liraglutide), SGLT-2 inhibitors (empagliflozin), DPP-4 inhibitors, sulfonylureas, insulin.
36
- 4. **Insulin:** Required if A1C not controlled with oral medications.
37
-
38
- ### Monitoring
39
-
40
- A1C: every 3 months until target, then every 6 months.
41
- Annual: eye exam (retinopathy), kidney function (creatinine, urine albumin), foot exam, lipids.
42
- Blood pressure target: < 130/80 mmHg.
43
-
44
- ### Hypoglycemia (low blood sugar, < 70 mg/dL)
45
-
46
- Symptoms: shaking, sweating, confusion, fast heartbeat, hunger.
47
- Treatment (Rule of 15): 15g fast-acting carbs (glucose tablets, 4oz juice, regular soda).
48
- Wait 15 minutes. Check blood sugar. Repeat if still < 70.
49
- Severe (unconscious): glucagon injection or call 911.
50
-
51
- ---
52
-
53
- ## Hypertension (High Blood Pressure)
54
-
55
- ### Staging (ACC/AHA 2017 guidelines)
56
-
57
- - Normal: < 120/80
58
- - Elevated: 120-129/< 80
59
- - Stage 1: 130-139/80-89
60
- - Stage 2: ≥ 140/≥ 90
61
- - Crisis: > 180/> 120
62
-
63
- ### Lifestyle modifications (proven to lower BP)
64
-
65
- - **Weight loss:** ~1 mmHg per kg lost
66
- - **DASH diet:** 8-14 mmHg reduction
67
- - **Sodium reduction:** < 2,300 mg/day; < 1,500 for greater effect. 4-9 mmHg reduction.
68
- - **Exercise:** 150 min/week moderate aerobic. 4-9 mmHg reduction.
69
- - **Limit alcohol:** ≤ 1 drink/day (women), ≤ 2/day (men). 2-4 mmHg reduction.
70
- - **Quit smoking:** Not directly antihypertensive but critical for cardiovascular risk.
71
-
72
- ### Medications
73
-
74
- **ACE inhibitors** (e.g., lisinopril, enalapril): First-line for many. Side effect: dry cough.
75
- **ARBs** (e.g., losartan, valsartan): Same mechanism, no cough. Used if ACE causes cough.
76
- **Calcium channel blockers** (amlodipine, diltiazem): Effective, well-tolerated.
77
- **Thiazide diuretics** (chlorthalidone, hydrochlorothiazide): Often first-line; older, inexpensive.
78
- **Beta-blockers** (metoprolol, carvedilol): Especially for heart failure or post-MI.
79
-
80
- **Note:** Never stop blood pressure medications without consulting your doctor.
81
- Even if you feel fine — hypertension is usually asymptomatic until serious events occur.
82
-
83
- ---
84
-
85
- ## Heart Disease (Coronary Artery Disease)
86
-
87
- ### Understanding your risk
88
-
89
- **ASCVD Risk Calculator** (ACC/AHA): Predicts 10-year cardiovascular event risk.
90
- Factors: age, sex, race, total cholesterol, HDL, systolic BP, BP treatment, diabetes, smoking.
91
-
92
- ### Statin therapy
93
-
94
- Statins reduce LDL and cardiovascular events.
95
- High-intensity (atorvastatin 40-80mg, rosuvastatin 20-40mg): Reduces LDL by ≥50%.
96
- Who benefits most: established heart disease, LDL ≥ 190, diabetes with risk factors, 10-year ASCVD risk ≥ 7.5%.
97
-
98
- **Muscle symptoms (myopathy/rhabdomyolysis):** Uncommon but report to doctor immediately.
99
- **Liver effects:** Routine monitoring not required; report jaundice or dark urine.
100
-
101
- ### Post-heart attack care
102
-
103
- Medications for life after MI:
104
-
105
- - Aspirin (81mg daily) unless contraindicated
106
- - Statin (high-intensity)
107
- - Beta-blocker (at least 1 year)
108
- - ACE inhibitor or ARB (if reduced ejection fraction)
109
- - P2Y12 inhibitor (clopidogrel, ticagrelor) for 1 year after stent
110
-
111
- Cardiac rehabilitation: structured exercise program after MI. Significantly reduces mortality. Underutilized.
112
-
113
- ---
114
-
115
- ## Asthma
116
-
117
- ### Monitoring and severity
118
-
119
- **Peak flow meter:** Track every morning. Personal best × 80% = green zone. Below 50% = red zone/emergency.
120
- **Spirometry:** FEV1 and FVC ratio measures airflow obstruction.
121
-
122
- ### Medications
123
-
124
- **Controller (daily, prevent symptoms):**
125
-
126
- - Inhaled corticosteroids (ICS): fluticasone, budesonide — most effective controller. Use daily regardless of symptoms.
127
- - Long-acting beta-agonist (LABA): salmeterol, formoterol. Never use alone; always with ICS.
128
- - Leukotriene modifiers: montelukast (Singulair). Less effective than ICS but oral, useful add-on.
129
- - Biologics: dupilumab, omalizumab for severe eosinophilic/allergic asthma.
130
-
131
- **Rescue (quick relief):**
132
-
133
- - Short-acting beta-agonist (SABA): albuterol — use for acute symptoms.
134
- - If using rescue > 2 days/week: asthma is not well-controlled; step up controller therapy.
135
-
136
- ### Asthma action plan
137
-
138
- Written plan with your doctor: what to do in green/yellow/red zones.
139
- Green: peak flow > 80% personal best. Take controller as prescribed.
140
- Yellow: peak flow 50-80%. Add extra rescue. Contact doctor if not improving.
141
- Red: peak flow < 50%. Take rescue. Seek emergency care if not improving immediately.
142
-
143
- ---
144
-
145
- ## COPD (Chronic Obstructive Pulmonary Disease)
146
-
147
- Main cause: smoking (80-85%). Also: occupational dust, fumes, indoor air pollution.
148
- Progressive and irreversible — but progression can be slowed.
149
-
150
- **GOLD staging (based on FEV1):**
151
- Grade 1 (mild): FEV1 ≥ 80% predicted
152
- Grade 2 (moderate): 50-79%
153
- Grade 3 (severe): 30-49%
154
- Grade 4 (very severe): < 30%
155
-
156
- ### Management
157
-
158
- **Most important:** Smoking cessation. The only intervention proven to slow progression.
159
- **Vaccinations:** Annual flu, pneumococcal, COVID. Respiratory infections are major triggers.
160
- **Pulmonary rehabilitation:** Structured exercise + education. Improves exercise tolerance and quality of life.
161
-
162
- **Bronchodilators:**
163
- LAMA (tiotropium, umeclidinium): Long-acting muscarinic antagonist. First-line for most.
164
- LABA: Long-acting beta-agonist. Often combined with LAMA.
165
- SABA/SAMA: Short-acting rescue inhalers.
166
- ICS: For frequent exacerbations + eosinophilic inflammation.
167
-
168
- **Oxygen therapy:** If O2 saturation consistently ≤ 88%. Use ≥ 15 hours/day to benefit.
169
-
170
- ---
171
-
172
- ## Arthritis
173
-
174
- ### Osteoarthritis (OA)
175
-
176
- Degenerative joint disease. Cartilage breakdown. Wear and tear.
177
- Most common in: knees, hips, hands, spine.
178
- No disease-modifying treatment — manage symptoms.
179
-
180
- **Management:**
181
-
182
- 1. Exercise: water aerobics, swimming, cycling. Strengthening around joint.
183
- 2. Weight loss: 10lb loss reduces knee force by 40lb per step.
184
- 3. Physical therapy: movement and strengthening strategies.
185
- 4. Acetaminophen (Tylenol): First-line analgesic. Max 3g/day (2g if liver disease).
186
- 5. NSAIDs (ibuprofen, naproxen): Effective but GI/cardiovascular/kidney risks.
187
- 6. Topical NSAIDs (diclofenac gel): Less systemic absorption; good for knee OA.
188
- 7. Intraarticular corticosteroids: Temporary relief for acute flares.
189
- 8. Joint replacement: When conservative management fails.
190
-
191
- ### Rheumatoid Arthritis (RA)
192
-
193
- Autoimmune inflammatory joint disease. Symmetrical small joints. Morning stiffness.
194
- Aggressive early treatment prevents joint damage. Treat-to-target approach.
195
-
196
- **DMARDs (Disease-Modifying Antirheumatic Drugs):**
197
- Methotrexate: First-line. Weekly oral dosing. Requires folic acid supplementation.
198
- Biologics (TNF inhibitors: etanercept, adalimumab; JAK inhibitors: tofacitinib): For inadequate methotrexate response.
199
-
200
- Sources: American Diabetes Association (diabetes.org), ACC/AHA Hypertension Guidelines,
201
- NHLBI Asthma Guidelines (nhlbi.nih.gov), GOLD COPD Guidelines (goldcopd.org),
202
- CDC chronic disease resources (cdc.gov/chronicdisease), ACR Rheumatoid Arthritis Guidelines
1
+ ---
2
+ watermark: ORIRO
3
+ disable-model-invocation: true
4
+ name: health-chronic
5
+ provider: ORIRO.ai
6
+ copyright: Copyright (c) 2026 ORIRO.ai
7
+ description: >
8
+ Chronic disease management — diabetes, hypertension, heart disease, asthma,
9
+ COPD, arthritis. Activate for questions about managing chronic conditions,
10
+ understanding treatment plans, lifestyle modifications, monitoring, or
11
+ any chronic disease management question. Sources: ADA, ACC/AHA guidelines,
12
+ CDC chronic disease resources, NHLBI. Always work with your healthcare team.
13
+ ---
14
+
15
+ # Chronic Disease Management
16
+
17
+ ## Diabetes
18
+
19
+ ### Type 1 vs. Type 2
20
+
21
+ **Type 1:** Autoimmune destruction of beta cells. No insulin production. Requires insulin for survival.
22
+ **Type 2:** Insulin resistance + declining beta cell function. Progressive. Most common form (90-95%).
23
+ **Prediabetes:** Fasting glucose 100-125 mg/dL or A1C 5.7-6.4%. Reversible with lifestyle.
24
+
25
+ ### Blood sugar targets (ADA guidelines)
26
+
27
+ - Fasting/pre-meal: 80-130 mg/dL
28
+ - 2 hours after meals: < 180 mg/dL
29
+ - A1C: < 7% for most adults (less stringent for elderly/complex)
30
+
31
+ ### Type 2 management hierarchy
32
+
33
+ 1. **Lifestyle first:** Weight loss (even 5-10% significantly improves glucose), exercise, diet.
34
+ 2. **Metformin:** First-line medication. Cheap, effective, well-tolerated. Take with food.
35
+ 3. **Add-on medications:** GLP-1 agonists (semaglutide, liraglutide), SGLT-2 inhibitors (empagliflozin), DPP-4 inhibitors, sulfonylureas, insulin.
36
+ 4. **Insulin:** Required if A1C not controlled with oral medications.
37
+
38
+ ### Monitoring
39
+
40
+ A1C: every 3 months until target, then every 6 months.
41
+ Annual: eye exam (retinopathy), kidney function (creatinine, urine albumin), foot exam, lipids.
42
+ Blood pressure target: < 130/80 mmHg.
43
+
44
+ ### Hypoglycemia (low blood sugar, < 70 mg/dL)
45
+
46
+ Symptoms: shaking, sweating, confusion, fast heartbeat, hunger.
47
+ Treatment (Rule of 15): 15g fast-acting carbs (glucose tablets, 4oz juice, regular soda).
48
+ Wait 15 minutes. Check blood sugar. Repeat if still < 70.
49
+ Severe (unconscious): glucagon injection or call 911.
50
+
51
+ ---
52
+
53
+ ## Hypertension (High Blood Pressure)
54
+
55
+ ### Staging (ACC/AHA 2017 guidelines)
56
+
57
+ - Normal: < 120/80
58
+ - Elevated: 120-129/< 80
59
+ - Stage 1: 130-139/80-89
60
+ - Stage 2: ≥ 140/≥ 90
61
+ - Crisis: > 180/> 120
62
+
63
+ ### Lifestyle modifications (proven to lower BP)
64
+
65
+ - **Weight loss:** ~1 mmHg per kg lost
66
+ - **DASH diet:** 8-14 mmHg reduction
67
+ - **Sodium reduction:** < 2,300 mg/day; < 1,500 for greater effect. 4-9 mmHg reduction.
68
+ - **Exercise:** 150 min/week moderate aerobic. 4-9 mmHg reduction.
69
+ - **Limit alcohol:** ≤ 1 drink/day (women), ≤ 2/day (men). 2-4 mmHg reduction.
70
+ - **Quit smoking:** Not directly antihypertensive but critical for cardiovascular risk.
71
+
72
+ ### Medications
73
+
74
+ **ACE inhibitors** (e.g., lisinopril, enalapril): First-line for many. Side effect: dry cough.
75
+ **ARBs** (e.g., losartan, valsartan): Same mechanism, no cough. Used if ACE causes cough.
76
+ **Calcium channel blockers** (amlodipine, diltiazem): Effective, well-tolerated.
77
+ **Thiazide diuretics** (chlorthalidone, hydrochlorothiazide): Often first-line; older, inexpensive.
78
+ **Beta-blockers** (metoprolol, carvedilol): Especially for heart failure or post-MI.
79
+
80
+ **Note:** Never stop blood pressure medications without consulting your doctor.
81
+ Even if you feel fine — hypertension is usually asymptomatic until serious events occur.
82
+
83
+ ---
84
+
85
+ ## Heart Disease (Coronary Artery Disease)
86
+
87
+ ### Understanding your risk
88
+
89
+ **ASCVD Risk Calculator** (ACC/AHA): Predicts 10-year cardiovascular event risk.
90
+ Factors: age, sex, race, total cholesterol, HDL, systolic BP, BP treatment, diabetes, smoking.
91
+
92
+ ### Statin therapy
93
+
94
+ Statins reduce LDL and cardiovascular events.
95
+ High-intensity (atorvastatin 40-80mg, rosuvastatin 20-40mg): Reduces LDL by ≥50%.
96
+ Who benefits most: established heart disease, LDL ≥ 190, diabetes with risk factors, 10-year ASCVD risk ≥ 7.5%.
97
+
98
+ **Muscle symptoms (myopathy/rhabdomyolysis):** Uncommon but report to doctor immediately.
99
+ **Liver effects:** Routine monitoring not required; report jaundice or dark urine.
100
+
101
+ ### Post-heart attack care
102
+
103
+ Medications for life after MI:
104
+
105
+ - Aspirin (81mg daily) unless contraindicated
106
+ - Statin (high-intensity)
107
+ - Beta-blocker (at least 1 year)
108
+ - ACE inhibitor or ARB (if reduced ejection fraction)
109
+ - P2Y12 inhibitor (clopidogrel, ticagrelor) for 1 year after stent
110
+
111
+ Cardiac rehabilitation: structured exercise program after MI. Significantly reduces mortality. Underutilized.
112
+
113
+ ---
114
+
115
+ ## Asthma
116
+
117
+ ### Monitoring and severity
118
+
119
+ **Peak flow meter:** Track every morning. Personal best × 80% = green zone. Below 50% = red zone/emergency.
120
+ **Spirometry:** FEV1 and FVC ratio measures airflow obstruction.
121
+
122
+ ### Medications
123
+
124
+ **Controller (daily, prevent symptoms):**
125
+
126
+ - Inhaled corticosteroids (ICS): fluticasone, budesonide — most effective controller. Use daily regardless of symptoms.
127
+ - Long-acting beta-agonist (LABA): salmeterol, formoterol. Never use alone; always with ICS.
128
+ - Leukotriene modifiers: montelukast (Singulair). Less effective than ICS but oral, useful add-on.
129
+ - Biologics: dupilumab, omalizumab for severe eosinophilic/allergic asthma.
130
+
131
+ **Rescue (quick relief):**
132
+
133
+ - Short-acting beta-agonist (SABA): albuterol — use for acute symptoms.
134
+ - If using rescue > 2 days/week: asthma is not well-controlled; step up controller therapy.
135
+
136
+ ### Asthma action plan
137
+
138
+ Written plan with your doctor: what to do in green/yellow/red zones.
139
+ Green: peak flow > 80% personal best. Take controller as prescribed.
140
+ Yellow: peak flow 50-80%. Add extra rescue. Contact doctor if not improving.
141
+ Red: peak flow < 50%. Take rescue. Seek emergency care if not improving immediately.
142
+
143
+ ---
144
+
145
+ ## COPD (Chronic Obstructive Pulmonary Disease)
146
+
147
+ Main cause: smoking (80-85%). Also: occupational dust, fumes, indoor air pollution.
148
+ Progressive and irreversible — but progression can be slowed.
149
+
150
+ **GOLD staging (based on FEV1):**
151
+ Grade 1 (mild): FEV1 ≥ 80% predicted
152
+ Grade 2 (moderate): 50-79%
153
+ Grade 3 (severe): 30-49%
154
+ Grade 4 (very severe): < 30%
155
+
156
+ ### Management
157
+
158
+ **Most important:** Smoking cessation. The only intervention proven to slow progression.
159
+ **Vaccinations:** Annual flu, pneumococcal, COVID. Respiratory infections are major triggers.
160
+ **Pulmonary rehabilitation:** Structured exercise + education. Improves exercise tolerance and quality of life.
161
+
162
+ **Bronchodilators:**
163
+ LAMA (tiotropium, umeclidinium): Long-acting muscarinic antagonist. First-line for most.
164
+ LABA: Long-acting beta-agonist. Often combined with LAMA.
165
+ SABA/SAMA: Short-acting rescue inhalers.
166
+ ICS: For frequent exacerbations + eosinophilic inflammation.
167
+
168
+ **Oxygen therapy:** If O2 saturation consistently ≤ 88%. Use ≥ 15 hours/day to benefit.
169
+
170
+ ---
171
+
172
+ ## Arthritis
173
+
174
+ ### Osteoarthritis (OA)
175
+
176
+ Degenerative joint disease. Cartilage breakdown. Wear and tear.
177
+ Most common in: knees, hips, hands, spine.
178
+ No disease-modifying treatment — manage symptoms.
179
+
180
+ **Management:**
181
+
182
+ 1. Exercise: water aerobics, swimming, cycling. Strengthening around joint.
183
+ 2. Weight loss: 10lb loss reduces knee force by 40lb per step.
184
+ 3. Physical therapy: movement and strengthening strategies.
185
+ 4. Acetaminophen (Tylenol): First-line analgesic. Max 3g/day (2g if liver disease).
186
+ 5. NSAIDs (ibuprofen, naproxen): Effective but GI/cardiovascular/kidney risks.
187
+ 6. Topical NSAIDs (diclofenac gel): Less systemic absorption; good for knee OA.
188
+ 7. Intraarticular corticosteroids: Temporary relief for acute flares.
189
+ 8. Joint replacement: When conservative management fails.
190
+
191
+ ### Rheumatoid Arthritis (RA)
192
+
193
+ Autoimmune inflammatory joint disease. Symmetrical small joints. Morning stiffness.
194
+ Aggressive early treatment prevents joint damage. Treat-to-target approach.
195
+
196
+ **DMARDs (Disease-Modifying Antirheumatic Drugs):**
197
+ Methotrexate: First-line. Weekly oral dosing. Requires folic acid supplementation.
198
+ Biologics (TNF inhibitors: etanercept, adalimumab; JAK inhibitors: tofacitinib): For inadequate methotrexate response.
199
+
200
+ Sources: American Diabetes Association (diabetes.org), ACC/AHA Hypertension Guidelines,
201
+ NHLBI Asthma Guidelines (nhlbi.nih.gov), GOLD COPD Guidelines (goldcopd.org),
202
+ CDC chronic disease resources (cdc.gov/chronicdisease), ACR Rheumatoid Arthritis Guidelines