@pikaa-ai/pikaa 0.3.1 → 0.3.4
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/dist/cli.js +1169 -601
- package/dist/index.js +525 -204
- package/package.json +5 -3
- package/skills/adaptyv/references/api-endpoints.md +0 -690
- package/skills/aeon/references/anomaly_detection.md +0 -154
- package/skills/aeon/references/classification.md +0 -144
- package/skills/aeon/references/clustering.md +0 -123
- package/skills/aeon/references/datasets_benchmarking.md +0 -392
- package/skills/aeon/references/distances.md +0 -256
- package/skills/aeon/references/forecasting.md +0 -109
- package/skills/aeon/references/networks.md +0 -289
- package/skills/aeon/references/regression.md +0 -118
- package/skills/aeon/references/segmentation.md +0 -163
- package/skills/aeon/references/similarity_search.md +0 -187
- package/skills/aeon/references/transformations.md +0 -246
- package/skills/analytical-method-validation/assets/validation-protocol-template.md +0 -106
- package/skills/analytical-method-validation/assets/validation-report-template.md +0 -116
- package/skills/analytical-method-validation/references/compendial-and-clsi.md +0 -96
- package/skills/analytical-method-validation/references/framework-selection.md +0 -87
- package/skills/analytical-method-validation/references/ich-m10-bioanalytical.md +0 -123
- package/skills/analytical-method-validation/references/ich-q2r2.md +0 -229
- package/skills/analytical-method-validation/references/source-ledger.md +0 -125
- package/skills/analytical-method-validation/references/statistics.md +0 -209
- package/skills/analytical-method-validation/scripts/_catalog.py +0 -499
- package/skills/analytical-method-validation/scripts/_common.py +0 -955
- package/skills/analytical-method-validation/scripts/check_accuracy_precision.py +0 -328
- package/skills/analytical-method-validation/scripts/check_bioanalytical_run.py +0 -293
- package/skills/analytical-method-validation/scripts/check_detection_limits.py +0 -310
- package/skills/analytical-method-validation/scripts/check_response.py +0 -243
- package/skills/analytical-method-validation/scripts/compare_methods.py +0 -215
- package/skills/analytical-method-validation/scripts/plan_validation.py +0 -381
- package/skills/anndata/references/best_practices.md +0 -532
- package/skills/anndata/references/concatenation.md +0 -399
- package/skills/anndata/references/data_structure.md +0 -314
- package/skills/anndata/references/io_operations.md +0 -466
- package/skills/anndata/references/manipulation.md +0 -516
- package/skills/arbor/references/arbor-upstream.md +0 -91
- package/skills/arbor/references/executor-brief.md +0 -68
- package/skills/arbor/references/htr-methodology.md +0 -177
- package/skills/arbor/references/report-template.md +0 -39
- package/skills/arbor/scripts/tree.py +0 -564
- package/skills/arboreto/references/algorithms.md +0 -152
- package/skills/arboreto/references/basic_inference.md +0 -181
- package/skills/arboreto/references/distributed_computing.md +0 -242
- package/skills/arboreto/scripts/basic_grn_inference.py +0 -107
- package/skills/astropy/references/coordinates.md +0 -280
- package/skills/astropy/references/cosmology.md +0 -309
- package/skills/astropy/references/fits.md +0 -398
- package/skills/astropy/references/tables.md +0 -495
- package/skills/astropy/references/time.md +0 -412
- package/skills/astropy/references/units.md +0 -178
- package/skills/astropy/references/wcs_and_other_modules.md +0 -377
- package/skills/autoskill/config.yaml +0 -53
- package/skills/autoskill/references/https-proxy.md +0 -62
- package/skills/autoskill/references/screenpipe-config.yaml +0 -61
- package/skills/autoskill/scripts/autoskill.py +0 -35
- package/skills/autoskill/scripts/backends.py +0 -116
- package/skills/autoskill/scripts/cluster.py +0 -54
- package/skills/autoskill/scripts/doctor.py +0 -108
- package/skills/autoskill/scripts/fetch_window.py +0 -33
- package/skills/autoskill/scripts/match_skills.py +0 -46
- package/skills/autoskill/scripts/promote.py +0 -58
- package/skills/autoskill/scripts/redact.py +0 -40
- package/skills/autoskill/scripts/run.py +0 -194
- package/skills/autoskill/scripts/synthesize.py +0 -72
- package/skills/benchling-integration/references/api_endpoints.md +0 -883
- package/skills/benchling-integration/references/authentication.md +0 -390
- package/skills/benchling-integration/references/core_capabilities.md +0 -355
- package/skills/benchling-integration/references/eventbridge.md +0 -255
- package/skills/benchling-integration/references/sdk_reference.md +0 -772
- package/skills/bids/references/beps.yml +0 -637
- package/skills/bids/references/bids_schema.json +0 -21015
- package/skills/bids/references/bids_specification.md +0 -165
- package/skills/bids/references/conversion_tools.md +0 -475
- package/skills/bids/references/core_workflows.md +0 -552
- package/skills/bids/references/metadata_fields.md +0 -365
- package/skills/bids/scripts/update_schema.py +0 -89
- package/skills/biopython/references/advanced.md +0 -580
- package/skills/biopython/references/alignment.md +0 -377
- package/skills/biopython/references/blast.md +0 -463
- package/skills/biopython/references/databases.md +0 -492
- package/skills/biopython/references/phylogenetics.md +0 -566
- package/skills/biopython/references/sequence_io.md +0 -289
- package/skills/biopython/references/structure.md +0 -564
- package/skills/bioservices/references/identifier_mapping.md +0 -685
- package/skills/bioservices/references/services_reference.md +0 -638
- package/skills/bioservices/references/workflow_patterns.md +0 -813
- package/skills/bioservices/scripts/batch_id_converter.py +0 -347
- package/skills/bioservices/scripts/compound_cross_reference.py +0 -387
- package/skills/bioservices/scripts/pathway_analysis.py +0 -309
- package/skills/bioservices/scripts/protein_analysis_workflow.py +0 -441
- package/skills/bulk-rnaseq/references/counts-and-handoff.md +0 -91
- package/skills/bulk-rnaseq/references/design-and-qc.md +0 -68
- package/skills/bulk-rnaseq/references/upstream-manual.md +0 -128
- package/skills/bulk-rnaseq/references/upstream-nfcore.md +0 -108
- package/skills/bulk-rnaseq/scripts/build_counts_matrix.py +0 -203
- package/skills/bulk-rnaseq/scripts/validate_samplesheet.py +0 -206
- package/skills/cellxgene-census/references/census_schema.md +0 -218
- package/skills/cellxgene-census/references/common_patterns.md +0 -368
- package/skills/cellxgene-census/references/core_workflow_patterns.md +0 -297
- package/skills/cirq/references/building.md +0 -307
- package/skills/cirq/references/experiments.md +0 -572
- package/skills/cirq/references/hardware.md +0 -527
- package/skills/cirq/references/noise.md +0 -514
- package/skills/cirq/references/simulation.md +0 -353
- package/skills/cirq/references/transformation.md +0 -416
- package/skills/citation-management/assets/bibtex_template.bib +0 -264
- package/skills/citation-management/assets/citation_checklist.md +0 -386
- package/skills/citation-management/references/best_practices.md +0 -91
- package/skills/citation-management/references/bibtex_formatting.md +0 -908
- package/skills/citation-management/references/citation_validation.md +0 -835
- package/skills/citation-management/references/core_workflow.md +0 -569
- package/skills/citation-management/references/example_workflows.md +0 -126
- package/skills/citation-management/references/google_scholar_search.md +0 -732
- package/skills/citation-management/references/metadata_extraction.md +0 -870
- package/skills/citation-management/references/pubmed_search.md +0 -839
- package/skills/citation-management/references/script_reference.md +0 -250
- package/skills/citation-management/references/search_strategies.md +0 -110
- package/skills/citation-management/scripts/_common.py +0 -331
- package/skills/citation-management/scripts/doi_to_bibtex.py +0 -204
- package/skills/citation-management/scripts/extract_metadata.py +0 -690
- package/skills/citation-management/scripts/format_bibtex.py +0 -356
- package/skills/citation-management/scripts/search_google_scholar.py +0 -268
- package/skills/citation-management/scripts/search_openalex.py +0 -297
- package/skills/citation-management/scripts/search_pubmed.py +0 -419
- package/skills/citation-management/scripts/validate_citations.py +0 -688
- package/skills/clinical-decision-support/assets/aggregate_cohort_table_template.json +0 -114
- package/skills/clinical-decision-support/assets/aggregate_model_evaluation_template.json +0 -115
- package/skills/clinical-decision-support/assets/artifact_intended_use_template.json +0 -81
- package/skills/clinical-decision-support/assets/decision_logic_traceability_template.json +0 -108
- package/skills/clinical-decision-support/assets/deidentification_checklist_template.json +0 -176
- package/skills/clinical-decision-support/assets/evidence_profile_template.json +0 -139
- package/skills/clinical-decision-support/assets/survival_analysis_plan_template.json +0 -134
- package/skills/clinical-decision-support/references/cohort_evaluation.md +0 -142
- package/skills/clinical-decision-support/references/decision_logic_traceability.md +0 -146
- package/skills/clinical-decision-support/references/evidence_profiles.md +0 -153
- package/skills/clinical-decision-support/references/model_biomarker_evaluation.md +0 -152
- package/skills/clinical-decision-support/references/privacy_and_disclosure.md +0 -144
- package/skills/clinical-decision-support/references/regulatory_and_governance.md +0 -104
- package/skills/clinical-decision-support/references/safety_and_scope.md +0 -103
- package/skills/clinical-decision-support/references/security_validation.md +0 -60
- package/skills/clinical-decision-support/references/sources.md +0 -119
- package/skills/clinical-decision-support/references/study_reporting.md +0 -134
- package/skills/clinical-decision-support/references/survival_analysis.md +0 -156
- package/skills/clinical-decision-support/scripts/_common.py +0 -223
- package/skills/clinical-decision-support/scripts/cohort_table_generator.py +0 -288
- package/skills/clinical-decision-support/scripts/decision_logic_traceability.py +0 -313
- package/skills/clinical-decision-support/scripts/deidentification_checklist.py +0 -260
- package/skills/clinical-decision-support/scripts/evidence_profile_check.py +0 -259
- package/skills/clinical-decision-support/scripts/model_biomarker_evaluation.py +0 -345
- package/skills/clinical-decision-support/scripts/survival_plan_validator.py +0 -294
- package/skills/clinical-decision-support/scripts/validate_cds_artifact.py +0 -269
- package/skills/clinical-reports/assets/adverse_event_aggregate_input_template.csv +0 -1
- package/skills/clinical-reports/assets/case_report_template.json +0 -43
- package/skills/clinical-reports/assets/clinical_trial_csr_template.json +0 -51
- package/skills/clinical-reports/assets/clinical_trial_results_template.json +0 -66
- package/skills/clinical-reports/assets/clinical_trial_safety_aggregate_template.json +0 -49
- package/skills/clinical-reports/assets/consistency_manifest_template.json +0 -15
- package/skills/clinical-reports/assets/deidentification_process_checklist.json +0 -56
- package/skills/clinical-reports/assets/lab_report_template.json +0 -36
- package/skills/clinical-reports/assets/pathology_report_template.json +0 -36
- package/skills/clinical-reports/assets/provenance_manifest_template.json +0 -17
- package/skills/clinical-reports/assets/quality_review_checklist.json +0 -34
- package/skills/clinical-reports/assets/radiology_report_template.json +0 -34
- package/skills/clinical-reports/assets/research_summary_template.json +0 -36
- package/skills/clinical-reports/assets/terminology_manifest_template.json +0 -11
- package/skills/clinical-reports/assets/trial_protocol_reporting_checklist.json +0 -70
- package/skills/clinical-reports/references/case_report_guidelines.md +0 -72
- package/skills/clinical-reports/references/clinical_trial_reporting.md +0 -97
- package/skills/clinical-reports/references/data_presentation.md +0 -92
- package/skills/clinical-reports/references/diagnostic_reports_standards.md +0 -76
- package/skills/clinical-reports/references/medical_terminology.md +0 -84
- package/skills/clinical-reports/references/privacy_and_deidentification.md +0 -84
- package/skills/clinical-reports/references/professional_review.md +0 -78
- package/skills/clinical-reports/references/report_type_routing.md +0 -57
- package/skills/clinical-reports/references/safety_reporting.md +0 -109
- package/skills/clinical-reports/references/sources.md +0 -75
- package/skills/clinical-reports/scripts/_common.py +0 -263
- package/skills/clinical-reports/scripts/check_deidentification.py +0 -298
- package/skills/clinical-reports/scripts/consistency_checker.py +0 -390
- package/skills/clinical-reports/scripts/format_adverse_events.py +0 -455
- package/skills/clinical-reports/scripts/generate_report_template.py +0 -115
- package/skills/clinical-reports/scripts/provenance_validator.py +0 -263
- package/skills/clinical-reports/scripts/terminology_validator.py +0 -277
- package/skills/clinical-reports/scripts/validate_case_report.py +0 -278
- package/skills/clinical-reports/scripts/validate_trial_report.py +0 -534
- package/skills/cobrapy/references/api_quick_reference.md +0 -665
- package/skills/cobrapy/references/workflows.md +0 -600
- package/skills/consciousness-council/references/advanced-configurations.md +0 -96
- package/skills/dask/references/arrays.md +0 -495
- package/skills/dask/references/bags.md +0 -468
- package/skills/dask/references/best-practices.md +0 -277
- package/skills/dask/references/dataframes.md +0 -370
- package/skills/dask/references/futures.md +0 -541
- package/skills/dask/references/schedulers.md +0 -517
- package/skills/database-lookup/references/addgene.md +0 -38
- package/skills/database-lookup/references/alphafold.md +0 -52
- package/skills/database-lookup/references/alphavantage.md +0 -261
- package/skills/database-lookup/references/bea.md +0 -409
- package/skills/database-lookup/references/bindingdb.md +0 -85
- package/skills/database-lookup/references/biogrid.md +0 -110
- package/skills/database-lookup/references/bls.md +0 -235
- package/skills/database-lookup/references/brenda.md +0 -71
- package/skills/database-lookup/references/cbioportal.md +0 -206
- package/skills/database-lookup/references/census.md +0 -251
- package/skills/database-lookup/references/chebi.md +0 -103
- package/skills/database-lookup/references/chembl.md +0 -80
- package/skills/database-lookup/references/clinicaltrials.md +0 -86
- package/skills/database-lookup/references/clinpgx.md +0 -64
- package/skills/database-lookup/references/clinvar.md +0 -91
- package/skills/database-lookup/references/cod.md +0 -121
- package/skills/database-lookup/references/cosmic.md +0 -59
- package/skills/database-lookup/references/dailymed.md +0 -65
- package/skills/database-lookup/references/database_selection_guide.md +0 -166
- package/skills/database-lookup/references/datacommons.md +0 -237
- package/skills/database-lookup/references/dbsnp.md +0 -143
- package/skills/database-lookup/references/disgenet.md +0 -52
- package/skills/database-lookup/references/drugbank.md +0 -54
- package/skills/database-lookup/references/ecb.md +0 -191
- package/skills/database-lookup/references/emdb.md +0 -37
- package/skills/database-lookup/references/ena.md +0 -372
- package/skills/database-lookup/references/encode.md +0 -47
- package/skills/database-lookup/references/ensembl.md +0 -539
- package/skills/database-lookup/references/epa.md +0 -232
- package/skills/database-lookup/references/eurostat.md +0 -237
- package/skills/database-lookup/references/fda.md +0 -64
- package/skills/database-lookup/references/federal-reserve.md +0 -216
- package/skills/database-lookup/references/fred.md +0 -297
- package/skills/database-lookup/references/gene-ontology.md +0 -147
- package/skills/database-lookup/references/geo.md +0 -130
- package/skills/database-lookup/references/gnomad.md +0 -93
- package/skills/database-lookup/references/gtex.md +0 -136
- package/skills/database-lookup/references/gwas-catalog.md +0 -46
- package/skills/database-lookup/references/hca.md +0 -35
- package/skills/database-lookup/references/hpo.md +0 -48
- package/skills/database-lookup/references/human-protein-atlas.md +0 -57
- package/skills/database-lookup/references/interpro.md +0 -120
- package/skills/database-lookup/references/jaspar.md +0 -50
- package/skills/database-lookup/references/kegg.md +0 -78
- package/skills/database-lookup/references/lincs-l1000.md +0 -68
- package/skills/database-lookup/references/materials-project.md +0 -123
- package/skills/database-lookup/references/metabolomics-workbench.md +0 -98
- package/skills/database-lookup/references/monarch.md +0 -46
- package/skills/database-lookup/references/mousemine.md +0 -40
- package/skills/database-lookup/references/nasa-exoplanet-archive.md +0 -112
- package/skills/database-lookup/references/nasa.md +0 -121
- package/skills/database-lookup/references/ncbi-gene.md +0 -64
- package/skills/database-lookup/references/ncbi-protein.md +0 -104
- package/skills/database-lookup/references/ncbi-taxonomy.md +0 -121
- package/skills/database-lookup/references/nist.md +0 -105
- package/skills/database-lookup/references/noaa.md +0 -199
- package/skills/database-lookup/references/omim.md +0 -114
- package/skills/database-lookup/references/opentargets.md +0 -459
- package/skills/database-lookup/references/openweathermap.md +0 -255
- package/skills/database-lookup/references/pdb.md +0 -121
- package/skills/database-lookup/references/pride.md +0 -74
- package/skills/database-lookup/references/pubchem.md +0 -145
- package/skills/database-lookup/references/quickgo.md +0 -45
- package/skills/database-lookup/references/reactome.md +0 -140
- package/skills/database-lookup/references/retrieval-contract.md +0 -123
- package/skills/database-lookup/references/rummageo.md +0 -32
- package/skills/database-lookup/references/sdss.md +0 -130
- package/skills/database-lookup/references/sec-edgar.md +0 -315
- package/skills/database-lookup/references/simbad.md +0 -405
- package/skills/database-lookup/references/sra.md +0 -149
- package/skills/database-lookup/references/string.md +0 -283
- package/skills/database-lookup/references/tcga-gdc.md +0 -58
- package/skills/database-lookup/references/treasury.md +0 -215
- package/skills/database-lookup/references/ucsc-genome.md +0 -135
- package/skills/database-lookup/references/uniprot.md +0 -283
- package/skills/database-lookup/references/usgs.md +0 -260
- package/skills/database-lookup/references/uspto.md +0 -130
- package/skills/database-lookup/references/who.md +0 -283
- package/skills/database-lookup/references/worldbank.md +0 -239
- package/skills/database-lookup/references/zinc.md +0 -202
- package/skills/datamol/references/conformers_module.md +0 -131
- package/skills/datamol/references/core_api.md +0 -136
- package/skills/datamol/references/core_workflows.md +0 -451
- package/skills/datamol/references/descriptors_viz.md +0 -195
- package/skills/datamol/references/fragments_scaffolds.md +0 -174
- package/skills/datamol/references/io_module.md +0 -112
- package/skills/datamol/references/reactions_data.md +0 -218
- package/skills/datamol/references/workflow_patterns.md +0 -104
- package/skills/deepchem/references/api_reference.md +0 -305
- package/skills/deepchem/references/core_capabilities.md +0 -276
- package/skills/deepchem/references/typical_workflows.md +0 -109
- package/skills/deepchem/references/workflows.md +0 -491
- package/skills/deepchem/scripts/graph_neural_network.py +0 -350
- package/skills/deepchem/scripts/predict_solubility.py +0 -223
- package/skills/deepchem/scripts/transfer_learning.py +0 -443
- package/skills/deepspot-m/references/api.md +0 -186
- package/skills/deepspot-m/references/whole_slide.md +0 -174
- package/skills/deeptools/assets/quick_reference.md +0 -65
- package/skills/deeptools/references/core_workflows.md +0 -134
- package/skills/deeptools/references/effective_genome_sizes.md +0 -118
- package/skills/deeptools/references/normalization_methods.md +0 -424
- package/skills/deeptools/references/tools_reference.md +0 -569
- package/skills/deeptools/references/workflows.md +0 -476
- package/skills/deeptools/scripts/validate_files.py +0 -195
- package/skills/deeptools/scripts/workflow_generator.py +0 -520
- package/skills/depmap/references/dependency_analysis.md +0 -178
- package/skills/dhdna-profiler/references/advanced-profiling.md +0 -72
- package/skills/diffdock/assets/batch_template.csv +0 -4
- package/skills/diffdock/assets/custom_inference_config.yaml +0 -94
- package/skills/diffdock/references/confidence_and_limitations.md +0 -182
- package/skills/diffdock/references/parameters_reference.md +0 -173
- package/skills/diffdock/references/workflows_examples.md +0 -401
- package/skills/diffdock/scripts/analyze_results.py +0 -346
- package/skills/diffdock/scripts/prepare_batch_csv.py +0 -257
- package/skills/diffdock/scripts/setup_check.py +0 -283
- package/skills/dnanexus-integration/references/app-development.md +0 -371
- package/skills/dnanexus-integration/references/authentication.md +0 -226
- package/skills/dnanexus-integration/references/configuration.md +0 -444
- package/skills/dnanexus-integration/references/data-operations.md +0 -474
- package/skills/dnanexus-integration/references/job-execution.md +0 -482
- package/skills/dnanexus-integration/references/operations-and-troubleshooting.md +0 -506
- package/skills/dnanexus-integration/references/python-sdk.md +0 -548
- package/skills/dnanexus-integration/references/sources.md +0 -168
- package/skills/dnanexus-integration/references/workflow-languages.md +0 -292
- package/skills/dnanexus-integration/scripts/inspect_dxpy.py +0 -366
- package/skills/dnanexus-integration/scripts/validate_dxapp.py +0 -796
- package/skills/docx/LICENSE.txt +0 -30
- package/skills/docx/scripts/__init__.py +0 -1
- package/skills/docx/scripts/accept_changes.py +0 -135
- package/skills/docx/scripts/comment.py +0 -368
- package/skills/docx/scripts/merge_runs.py +0 -310
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- package/skills/xlsx/scripts/office/schemas/microsoft/wml-cid-2016.xsd +0 -13
- package/skills/xlsx/scripts/office/schemas/microsoft/wml-sdtdatahash-2020.xsd +0 -4
- package/skills/xlsx/scripts/office/schemas/microsoft/wml-symex-2015.xsd +0 -8
- package/skills/xlsx/scripts/office/soffice.py +0 -232
- package/skills/xlsx/scripts/office/validate.py +0 -173
- package/skills/xlsx/scripts/office/validators/__init__.py +0 -15
- package/skills/xlsx/scripts/office/validators/base.py +0 -875
- package/skills/xlsx/scripts/office/validators/docx.py +0 -466
- package/skills/xlsx/scripts/office/validators/pptx.py +0 -441
- package/skills/xlsx/scripts/office/validators/redlining.py +0 -299
- package/skills/xlsx/scripts/recalc.py +0 -308
- package/skills/zarr-python/references/api_reference.md +0 -162
- package/skills/zarr-python/references/chunking_and_compression.md +0 -138
- package/skills/zarr-python/references/integration.md +0 -147
- package/skills/zarr-python/references/performance_and_patterns.md +0 -198
- package/skills/zarr-python/references/storage_backends.md +0 -91
- package/skills/zarr-python/references/v3_migration.md +0 -127
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# build123d 0.11.1 patterns
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An API cookbook for the geometry this skill actually needs. Every snippet here was run against
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build123d 0.11.1 on Python 3.12.
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## Builder mode or algebra mode
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build123d offers two equivalent APIs.
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```python
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# Builder mode: a context manager collects operations. mode= controls the boolean.
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with BuildPart() as ex:
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Box(80.0, 60.0, 10.0)
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Cylinder(radius=11.0, height=10.0, mode=Mode.SUBTRACT)
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part = ex.part
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# Algebra mode: plain objects and operators.
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part = Box(80.0, 60.0, 10.0) - Cylinder(radius=11.0, height=10.0)
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```
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**Use builder mode for parts in this skill.** Selectors (`ex.edges()`, `ex.faces()`) read naturally
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from the builder, which is what you need for fillets and for placing features on found faces.
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Algebra mode is a good fit for short, purely constructive shapes.
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Do not mix the two styles inside one `build()`.
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## The model file contract
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`gen.py` imports the module, calls `build()`, and then reads `interfaces()`. Parameters must be
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module-level so they can be overridden with `--param`.
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```python
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"""One-line description of the part.
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Process: SLA, tough resin. Orientation: bore axis vertical.
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Interfaces:
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- Rod bores: 30 mm cage system, Thorlabs ER series (cage-system-30mm).
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"""
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from build123d import *
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# --- INTERFACE (fixed; do not tune) ---
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rod_spacing_mm = 30.0 # cage-system-30mm
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rod_bore_d_mm = 6.4 # rod_diameter 6.0 + 2 x 0.20 SLA free-sliding (fabrication-limits.md)
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# --- DESIGN (free) ---
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plate_t_mm = 8.9
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aperture_d_mm = 25.4
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def interfaces() -> list[dict]:
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return [
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{"feature": "cage rod bore spacing", "standard": "cage-system-30mm",
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"dimension": "rod_spacing", "value": rod_spacing_mm, "intent": "match"},
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{"feature": "cage rod bore diameter", "standard": "cage-system-30mm",
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"dimension": "rod_diameter", "value": rod_bore_d_mm,
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"intent": "envelope", "clearance": 0.4},
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]
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def build() -> Part:
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half = rod_spacing_mm / 2
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with BuildPart() as plate:
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Box(rod_spacing_mm + 12.0, rod_spacing_mm + 12.0, plate_t_mm)
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with Locations((half, half), (-half, half), (half, -half), (-half, -half)):
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Hole(radius=rod_bore_d_mm / 2)
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Hole(radius=aperture_d_mm / 2)
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return plate.part
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```
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## Declaring interfaces
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Most lab-hardware interfaces are **internal features** — a pocket, a bore, a slot — and none of
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them appear in the part's outer bounding box. So `check.py fit` cannot find them by measuring the
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STEP, and hand-copying the number into `--value` reintroduces exactly the transcription error the
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skill exists to prevent. Declaring them closes the loop: `gen.py` records the declaration in the
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manifest, and `check.py interfaces` verifies every entry.
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Each entry needs `standard`, `dimension`, and `value`; `feature`, `intent`, and `clearance` are
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optional:
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| Key | Meaning |
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| --- | --- |
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| `standard` | ID from `check.py standards --list` |
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| `dimension` | a dimension name inside that standard |
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| `value` | the number **this model computed**, in mm |
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| `feature` | human label for the check output (default: the dimension name) |
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| `intent` | `match` if this part must itself conform; `envelope` if the feature must accept any conforming part (default: `match`) |
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| `clearance` | total intended clearance in mm, both sides (default: 0) |
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**Write `interfaces()` as a function, and compute derived dimensions inside functions.** A
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module-level `INTERFACES = [...]` list is also accepted, but it is evaluated at import — before
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`--param` is applied — so any value derived from an overridden parameter is recorded wrong. The same
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applies to the geometry: derive inside `build()` or a helper, never at module level.
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```python
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# Wrong: --param plate_tol_mm=0 silently leaves pocket_l_mm at the old value
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pocket_l_mm = plate_l_mm + plate_tol_mm + 2 * pocket_clearance_mm
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# Right: recomputed on every call, so overrides land
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def pocket_l_mm() -> float:
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return plate_l_mm + plate_tol_mm + 2 * pocket_clearance_mm
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```
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`gen.py` warns when it sees a static `INTERFACES` list together with `--param`.
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## Declaring geometry checks
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`interfaces()` compares declared numbers against the standards database; it never touches the
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solid. `checks()` is its measured counterpart: a list of **go/no-go gauges** evaluated by boolean
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intersection against the part `build()` actually produced. `gen.py` runs them on every
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generation and fails the build if one fails; `check.py geometry` re-runs them against an
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exported STEP.
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The principle: **every geometric requirement in the request maps to one entry.** Something must
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pass through (a screw, a beam, a probe) → a `clear` region. Something must fit into a void (a
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plate into a pocket) → a `clear` box the size of the mating part at maximum material condition.
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Something must remain (a ridge, a ledge, a screw seat) → a `material` region. A stated size
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limit → a `bbox_*` bound. These are exactly the errors `is_valid`, the bounding box, and a
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declared-number check cannot see.
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```python
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def checks() -> list[dict]:
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top = plate_t_mm / 2
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return [
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# a clear region: no material may intrude (screw shafts, through the part)
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{"feature": "M6 screws pass all four bores",
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"clear": {"cylinder": 6.0, "axis": "z", "at": bolt_xy()}},
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# a keep-out with an explicit span (a beam corridor along x at height z)
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{"feature": "beam clear at 15 mm above the bench",
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"clear": {"cylinder": 5.0, "axis": "x", "at": [(0.0, 15.0)]}},
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# a gauge part that must drop into a pocket: the mating part at MMC
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{"feature": "SLAS plate at MMC drops into the pocket",
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"clear": {"box": (128.01, 85.73, pocket_depth_mm()),
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"at": [(0.0, 0.0, floor_t_mm + pocket_depth_mm() / 2)]}},
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# a counterbore that really is a counterbore: recess open, seat present.
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# The second entry is what catches a recess that punched through.
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{"feature": "counterbore recess open at the top",
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"clear": {"cylinder": cbore_d_mm - 0.2, "axis": "z", "at": bolt_xy(),
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"span": (top - cbore_depth_mm + 0.1, top + 0.1)}},
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{"feature": "screw seat present below the recess",
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"material": {"cylinder": cbore_d_mm - 0.2, "axis": "z", "at": bolt_xy(),
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"span": (-top + 0.1, top - cbore_depth_mm - 0.1)},
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"min_mm3": 50.0},
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# a user-stated hard limit, measured from the solid
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{"feature": "clears the objective turret", "bbox_z": {"max": 15.0}},
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]
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```
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Semantics:
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| Key | Meaning |
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| --- | --- |
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| `clear` / `material` | region that must contain no material / must contain material |
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| `{"cylinder": DIA, "axis": "x"\|"y"\|"z", "at": [(a, b), ...], "span": (lo, hi)}` | `at` is 2D in the plane perpendicular to the axis — axis `z`: (x, y); axis `x`: (y, z); axis `y`: (x, z). Omit `span` to run through the whole part |
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| `{"box": (dx, dy, dz), "at": [(x, y, z), ...]}` | axis-aligned box gauges centred at each position |
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| `tol_mm3` / `min_mm3` | pass thresholds per position (both default 0.01) |
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| `bbox_x`…`bbox_z`, `bbox_min/mid/max` | `{"min": mm, "max": mm}` bounds on the measured bounding box |
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Size the gauges from the same named constants as the geometry **only when the requirement is
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relational** (the recess sits above the seat). When the requirement is absolute — a mating part's
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MMC, a user's height limit, a beam position — write the gauge from the requirement's own numbers,
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so a wrong parameter cannot shrink the gauge to match the wrong geometry.
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For a one-off question without editing the model, `check.py probe` runs a single gauge from the
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command line, and `check.py bores` prints a census of every cylindrical face (diameter, axis,
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position, span, sweep) to reconcile against the model's intent.
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## Positioning
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`Locations` places the objects created inside it. It is the workhorse for bolt patterns.
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```python
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with Locations((10.0, 0.0), (-10.0, 0.0)): # two positions on the current plane
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Hole(radius=3.3)
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with Locations((0.0, 0.0, floor_t_mm)): # offset in z
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Box(10.0, 10.0, 5.0, mode=Mode.SUBTRACT)
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with GridLocations(9.0, 9.0, 12, 8): # x spacing, y spacing, x count, y count
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Hole(radius=1.5)
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```
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`GridLocations` centres the grid on the origin. A microplate well grid is dimensioned from the
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plate corner instead, so compute absolute positions and pass them to `Locations`:
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```python
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a1_x_mm, a1_y_mm, pitch_mm = 14.38, 11.24, 9.0 # slas-well-positions-96
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origin_x = -plate_l_mm / 2
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origin_y = plate_w_mm / 2
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wells = [
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(origin_x + a1_x_mm + pitch_mm * col, origin_y - a1_y_mm - pitch_mm * row)
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for row in range(8) for col in range(12)
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]
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with Locations(*wells):
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Hole(radius=well_clear_d_mm / 2)
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```
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## Alignment
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By default objects are centred on the origin. `align` moves the datum, which is usually what you
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want for a pocket that starts at a floor:
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```python
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Box(x, y, z, align=(Align.CENTER, Align.CENTER, Align.MIN)) # sits on z = 0
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Box(x, y, z, align=(Align.MIN, Align.MIN, Align.MIN)) # corner at the origin
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```
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Getting this wrong is the classic "pocket cut through the floor" bug, and it is exactly what the
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snapshot catches.
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## Holes
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`Hole` cuts through the whole part; `CounterBoreHole` and `CounterSinkHole` add a head recess.
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**`CounterBoreHole` cuts downward from the workplane it is placed on, with the recess at that
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plane.** On a centred `Box` the default workplane is the mid-height of the part, so a 2-tuple
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location buries the screw seat inside the plate — or, on a thin plate, lets the recess swallow the
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top entirely, leaving a straight bore the screw head falls through. Place it on the **top face**
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(or give the location an explicit z at the top):
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```python
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with BuildPart() as plate:
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Box(60.0, 60.0, 10.0) # spans z = -5 .. +5
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top = plate.faces().sort_by(Axis.Z)[-1]
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with Locations(top):
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with Locations((20.0, 20.0)):
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CounterBoreHole(radius=6.6 / 2, counter_bore_radius=11.0 / 2,
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counter_bore_depth=6.5)
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```
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Size `counter_bore_depth` from the **screw head height**, not from habit: an M6 socket head cap
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screw head is 6.0 mm tall, a 1/4-20 head 6.35 mm (`screw_head_height` in the breadboard
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standards). A 4 mm counterbore leaves either head 2 mm proud — do not call that flush. After
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generating, confirm in the snapshot (or a section) that the recess is at the top face and the
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seat ledge exists; both failure modes here pass `is_valid` and the bounding box untouched.
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Remember that printed holes come out undersize — see `references/fabrication-limits.md`.
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## Selectors
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Selectors find edges and faces to fillet, chamfer, or build on. The three you need:
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```python
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part.edges().filter_by(Axis.Z) # keep edges parallel to Z (the vertical corners)
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part.edges().group_by(Axis.Z)[-1] # the group with the highest Z (the top edges)
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part.faces().sort_by(Axis.Z)[-1] # the single highest face
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part.edges().filter_by(GeomType.CIRCLE) # only circular edges
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```
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`filter_by` keeps everything matching. `group_by` partitions into lists ordered by the key, so
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`[-1]` is the last group and `[0]` the first. `sort_by` orders individual items.
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```python
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with BuildPart() as ex:
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Box(80.0, 60.0, 10.0)
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chamfer(ex.edges().group_by(Axis.Z)[-1], length=4.0) # chamfer the top face edges
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fillet(ex.edges().filter_by(Axis.Z), radius=5.0) # round the vertical corners
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```
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**These broad selectors are only safe on a part that is still a plain box.** Once the part has
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pockets, bores, notches, or micro-relief, `filter_by(Axis.Z)` and `group_by(Axis.Z)[-1]` also
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select the edges of those features, and the fillet either throws a kernel error
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(`Failed creating a fillet`, `BRep_API: command not done`) or — worse — succeeds and silently eats
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a wall or a 0.3 mm ridge. Both happen in practice. So:
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- Fillet or chamfer the **outer body before adding internal features**, or filter the selection
|
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down deliberately (by position, length, or `GeomType`) so only the intended edges remain.
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- Bound the radius with `part.max_fillet(edges)` when the nearby geometry is tight — it returns
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the largest radius the kernel can actually build on that edge set.
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- Make every fillet/chamfer radius a named parameter, and on a kernel failure back the value off
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rather than fighting the selector.
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- Then check the snapshot: a consumed feature is obvious in the picture and invisible in
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`is_valid`.
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## Sketch then extrude
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For a profile that is not a primitive, sketch it and extrude:
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```python
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with BuildPart() as bracket:
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with BuildSketch() as profile:
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Rectangle(40.0, 20.0)
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with Locations((15.0, 0.0)):
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Circle(radius=4.0, mode=Mode.SUBTRACT)
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extrude(amount=6.0)
|
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```
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This is also the route to a laser-cut DXF: the sketch is the cut profile.
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## Exports
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`gen.py` handles these, but for reference:
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```python
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export_step(part, "part.step", unit=Unit.MM) # authoritative
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export_stl(part, "part.stl", tolerance=1e-3, angular_tolerance=0.1)
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# 2D profile for laser cutting. section() is a module-level operation, NOT a
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# method on the shape -- part.section(...) raises AttributeError.
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from build123d.exporters import ColorIndex # NOT exported by `from build123d import *`
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profile = section(part, Plane.XY.offset(z_mm), mode=Mode.PRIVATE)
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profile = profile.moved(Location((0, 0, -z_mm))) # back to z = 0, or the DXF writer
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|
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|
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# warns about a non-planar shape
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|
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exporter = ExportDXF(unit=Unit.MM)
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|
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exporter.add_layer("CUT", color=ColorIndex.RED) # laser shops key power/speed to layers
|
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|
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exporter.add_shape(profile, layer="CUT")
|
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|
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exporter.write("part.dxf")
|
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|
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```
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310
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Cut the section through material, not at `z = 0`: a part modelled sitting on the build plate has
|
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|
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only a degenerate face there. `gen.py --dxf` defaults to the part's mid-height and takes `--dxf-z`
|
|
312
|
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to override.
|
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-
|
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314
|
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STEP preserves exact BREP geometry; STL is a triangulated approximation. **Always keep STEP as the
|
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315
|
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source of truth** and regenerate meshes from it, never the reverse.
|
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|
-
|
|
317
|
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## Measuring in code
|
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|
-
|
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319
|
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Useful for asserting an interface inside the model itself:
|
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|
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|
|
321
|
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```python
|
|
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|
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bbox = part.bounding_box()
|
|
323
|
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print(bbox.size.X, bbox.size.Y, bbox.size.Z)
|
|
324
|
-
print(part.volume, part.area)
|
|
325
|
-
print(part.is_valid) # a property in 0.11.1, not a method
|
|
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|
-
print(part.center(CenterOf.MASS))
|
|
327
|
-
```
|
|
328
|
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|
|
329
|
-
`is_valid` being a property rather than a method is a real difference from older releases and from
|
|
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|
-
some documentation. Access it without parentheses.
|
|
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|
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|
|
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|
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## Things that bite
|
|
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|
-
|
|
334
|
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- **`is_valid` is a property.** `part.is_valid()` raises `TypeError: 'bool' object is not callable`.
|
|
335
|
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- **`section()` is a module-level operation, not a method.** `part.section(Plane.XY)` raises
|
|
336
|
-
`AttributeError`. Call `section(part, plane, mode=Mode.PRIVATE)`.
|
|
337
|
-
- **`intersect()` returns a `ShapeList`** with no `.volume`; the `&` operator returns a `Solid` that
|
|
338
|
-
has one. `check.py clearance` handles both.
|
|
339
|
-
- **Never name a script `inspect.py`** in a directory that lands on `sys.path`. It shadows the
|
|
340
|
-
standard library `inspect` module, which breaks `typing_extensions` and therefore build123d
|
|
341
|
-
itself. This is why the bundled script is `check.py`.
|
|
342
|
-
- **Builder objects are not parts.** Return `builder.part`, not the builder.
|
|
343
|
-
- **`Mode.SUBTRACT` needs an existing body.** Subtracting from an empty context does nothing
|
|
344
|
-
silently.
|
|
345
|
-
- **A swept or extruded profile is centred on its path/plane unless you align it.** Sweeping a
|
|
346
|
-
`Rectangle(w, h)` along a path on a surface leaves half the profile below the surface — a
|
|
347
|
-
"0.3 mm ridge" that is really 0.15 mm proud. Pass `align=` (and an explicit `x_dir` on the
|
|
348
|
-
profile plane) so the profile sits where you think it does, then measure the result.
|
|
349
|
-
- **`Curve` has no `.length`.** Sum the edges instead: `sum(e.length for e in curve.edges())`.
|
|
350
|
-
- **The boolean of touching or disjoint solids is empty, not an error.** Depending on the path you
|
|
351
|
-
get `None`, an empty `Compound`, or a `ShapeList` with no `.volume` — guard before reading
|
|
352
|
-
`.volume` in any interference check.
|
|
353
|
-
- **`ColorIndex` and `LineType` live in `build123d.exporters`**, not in the top-level namespace;
|
|
354
|
-
`from build123d import *` does not bring them in, and `add_layer(color=1)` fails.
|
|
355
|
-
- The OpenCascade kernel raises assorted exception types. Catch broadly around boolean operations
|
|
356
|
-
and report the failure rather than letting a traceback escape.
|
|
357
|
-
|
|
358
|
-
## Sources
|
|
359
|
-
|
|
360
|
-
- build123d documentation — <https://build123d.readthedocs.io/en/latest/>
|
|
361
|
-
- Introductory examples (builder vs algebra, selectors, fillets) —
|
|
362
|
-
<https://build123d.readthedocs.io/en/latest/introductory_examples.html>
|
|
363
|
-
- Import/export reference — <https://build123d.readthedocs.io/en/latest/import_export.html>
|
|
@@ -1,156 +0,0 @@
|
|
|
1
|
-
# Fabrication limits, tolerances, and materials
|
|
2
|
-
|
|
3
|
-
Read this before finalising any geometry. Process determines what geometry is possible; material
|
|
4
|
-
determines whether the part survives the lab.
|
|
5
|
-
|
|
6
|
-
## Process tolerances
|
|
7
|
-
|
|
8
|
-
Achievable tolerance and minimum feature size, as planning figures. **Every number here depends on
|
|
9
|
-
the specific machine, material, and operator.** Use them to choose a process and to size a first
|
|
10
|
-
article, then verify with a test coupon.
|
|
11
|
-
|
|
12
|
-
| Process | Typical tolerance | Min wall | Min feature | Notes |
|
|
13
|
-
| --- | --- | --- | --- | --- |
|
|
14
|
-
| FDM | ±0.3 mm (often worse over 100 mm) | 1.2 mm (3 x 0.4 mm nozzle) | ~0.8 mm | Anisotropic: much weaker across layers. Porous. |
|
|
15
|
-
| SLA / DLP | ±0.1 mm | 0.8 mm | ~0.3 mm | Better surface and detail. Resin choice dominates properties. |
|
|
16
|
-
| SLS (nylon) | ±0.2 mm | 0.8 mm | ~0.5 mm | Isotropic, no supports, slightly porous surface. |
|
|
17
|
-
| CNC milling | ±0.05 mm or better | 0.8 mm in metal | Set by tool diameter | Internal corners carry the tool radius — you cannot mill a sharp internal corner. |
|
|
18
|
-
| Laser cutting | ±0.1 mm | n/a | Kerf ~0.1-0.3 mm | 2D only. Edge taper on thick stock. Kerf offset must be applied. |
|
|
19
|
-
|
|
20
|
-
Two consequences that catch people:
|
|
21
|
-
|
|
22
|
-
- **Holes print undersize** on both FDM and SLA. A 6.0 mm modelled hole typically measures under
|
|
23
|
-
6.0 mm. Oversize functional bores, or plan to ream them.
|
|
24
|
-
- **Internal corners cannot be sharp in milling.** If a milled pocket must accept a square part,
|
|
25
|
-
add corner relief cuts. (For a part with *rounded* corners the tool radius is harmless as long
|
|
26
|
-
as it stays at or below the part's minimum corner radius — see the corner-radius rule in
|
|
27
|
-
`references/labware-adapters.md`.)
|
|
28
|
-
|
|
29
|
-
### Laser cutting
|
|
30
|
-
|
|
31
|
-
- **Kerf direction is fixed by the physics, so get it right in the handover.** The beam removes a
|
|
32
|
-
strip of width k (~0.1–0.3 mm) centred on the drawn line. Cutting on the line therefore makes
|
|
33
|
-
**holes and internal cutouts come out oversize by ~k, and the part's outer outline undersize by
|
|
34
|
-
~k**. Say which convention the DXF uses (on-the-line is the default assumption) and let the shop
|
|
35
|
-
offset, or offset the geometry yourself and say so — never both.
|
|
36
|
-
- **Put cut geometry on a named layer** (one layer per operation: `CUT`, `ENGRAVE`). Shops key
|
|
37
|
-
power and speed to layer or colour; geometry on layer 0 forces them to guess.
|
|
38
|
-
- **Cut order matters:** internal features before the outer outline, or the part shifts once it is
|
|
39
|
-
freed from the sheet.
|
|
40
|
-
- **Sheet stock is not its nominal thickness.** "3 mm" acrylic commonly runs ~2.8–3.2 mm; slots
|
|
41
|
-
sized for nominal will be loose or tight. For solvent-welded joints prefer **cast** acrylic over
|
|
42
|
-
extruded — cleaner cut edge, less vapour crazing — and remember alcohols craze acrylic either
|
|
43
|
-
way (see Chemical, below).
|
|
44
|
-
- Laser-cut edges are sharp and slightly tapered; call out deburring or flame-polishing for
|
|
45
|
-
anything handled or animal-facing.
|
|
46
|
-
|
|
47
|
-
## Fits and clearances
|
|
48
|
-
|
|
49
|
-
Nominal dimensions do not produce fits. Choose a clearance deliberately, per side:
|
|
50
|
-
|
|
51
|
-
| Fit | FDM | SLA | CNC |
|
|
52
|
-
| --- | --- | --- | --- |
|
|
53
|
-
| Free-sliding (a plate dropping into a pocket) | 0.40 mm | 0.20 mm | 0.10 mm |
|
|
54
|
-
| Located but removable by hand | 0.25 mm | 0.10 mm | 0.05 mm |
|
|
55
|
-
| Press / interference | -0.05 mm | -0.03 mm | -0.02 mm |
|
|
56
|
-
|
|
57
|
-
Then remember the **other** part has tolerance too. When mating to a standardised component,
|
|
58
|
-
design the receiving feature against the component's **maximum material condition**, not its
|
|
59
|
-
nominal — a pocket sized from nominal fits only the smaller half of conforming parts. This is what
|
|
60
|
-
`intent: "envelope"` enforces. Declare it in the model and check the manifest:
|
|
61
|
-
|
|
62
|
-
```bash
|
|
63
|
-
python scripts/check.py interfaces out/part.manifest.json
|
|
64
|
-
```
|
|
65
|
-
|
|
66
|
-
Or check a single number by hand:
|
|
67
|
-
|
|
68
|
-
```bash
|
|
69
|
-
python scripts/check.py fit --standard slas-microplate-footprint \
|
|
70
|
-
--intent envelope --clearance 0.8 --value footprint_length=128.81
|
|
71
|
-
```
|
|
72
|
-
|
|
73
|
-
## Threads and inserts
|
|
74
|
-
|
|
75
|
-
**Printed threads are usually a mistake.** Layer resolution is comparable to the thread pitch, so
|
|
76
|
-
printed threads are weak, dimensionally unreliable, and shed particles.
|
|
77
|
-
|
|
78
|
-
In descending order of preference:
|
|
79
|
-
|
|
80
|
-
1. **Heat-set threaded inserts** — the standard solution for printed parts. Model a straight bore
|
|
81
|
-
to the insert manufacturer's specified diameter (it varies by insert; get the datasheet) and
|
|
82
|
-
provide enough surrounding wall, typically at least 2 mm.
|
|
83
|
-
2. **Clearance hole plus a captive nut** in a hex pocket. Reliable and cheap.
|
|
84
|
-
3. **Tapping the printed material directly** — acceptable for light, infrequently-assembled joints.
|
|
85
|
-
4. **Printing the thread** — only for coarse threads (roughly M6 and above), never for fine
|
|
86
|
-
threads like the 0.635 mm pitch SM1 (see `references/optomechanics.md`).
|
|
87
|
-
|
|
88
|
-
## Orientation and anisotropy
|
|
89
|
-
|
|
90
|
-
For FDM especially, orientation is a design decision, not a printing detail:
|
|
91
|
-
|
|
92
|
-
- Parts are substantially weaker **across** layers than along them. Orient so that load runs
|
|
93
|
-
along layers, and state the intended orientation in the model docstring.
|
|
94
|
-
- Overhangs beyond roughly 45 degrees need support, and supported surfaces come out rough and
|
|
95
|
-
dimensionally poor. If a surface is a sealing or mating face, orient it so it is not supported.
|
|
96
|
-
- Holes printed with their axis vertical are round; printed horizontally they come out with a
|
|
97
|
-
drooped top. Teardrop or chamfer horizontal holes that must stay round.
|
|
98
|
-
- **Every enclosed cavity needs a drain path** in resin printing. See
|
|
99
|
-
`references/microfluidics.md`.
|
|
100
|
-
|
|
101
|
-
## Materials
|
|
102
|
-
|
|
103
|
-
### Thermal
|
|
104
|
-
|
|
105
|
-
| Material | Approximate service limit | Autoclave (121 °C)? |
|
|
106
|
-
| --- | --- | --- |
|
|
107
|
-
| PLA | ~50-60 °C | **No** — distorts well below autoclave temperature |
|
|
108
|
-
| PETG | ~70-80 °C | No |
|
|
109
|
-
| ABS / ASA | ~90-100 °C | Marginal, generally no |
|
|
110
|
-
| Polypropylene | ~100 °C | Marginal |
|
|
111
|
-
| Nylon (SLS) | ~120-160 °C | Sometimes; verify per grade |
|
|
112
|
-
| PEEK | >250 °C | Yes |
|
|
113
|
-
| Stainless steel, aluminium, glass | High | Yes |
|
|
114
|
-
|
|
115
|
-
**Assume a printed part is not autoclavable unless it is a verified high-temperature material.**
|
|
116
|
-
Offer chemical or gas sterilisation as the alternative, and check that against the solvent notes
|
|
117
|
-
below.
|
|
118
|
-
|
|
119
|
-
### Chemical
|
|
120
|
-
|
|
121
|
-
- **Acrylic (PMMA)** crazes on contact with alcohols, including 70% ethanol — a serious problem in
|
|
122
|
-
a lab that disinfects everything with ethanol.
|
|
123
|
-
- **Polycarbonate** is attacked by many solvents and by some alkaline cleaners.
|
|
124
|
-
- **PLA** hydrolyses; it degrades in warm, wet, or repeatedly-cleaned service.
|
|
125
|
-
- **PP, PTFE, PEEK** have broad chemical resistance and are the safe choices for solvent contact.
|
|
126
|
-
|
|
127
|
-
Always ask what the part will be cleaned with, not just what it will contain. Cleaning agent
|
|
128
|
-
compatibility is more often the failure than the sample.
|
|
129
|
-
|
|
130
|
-
### Biocompatibility
|
|
131
|
-
|
|
132
|
-
- **Uncured SLA resin is cytotoxic.** Even nominally biocompatible resins require the
|
|
133
|
-
manufacturer's full post-cure and wash protocol, and leachables can still affect sensitive cell
|
|
134
|
-
assays.
|
|
135
|
-
- For anything contacting cells, tissue, or animals: prefer glass, medical-grade polymer, or PTFE
|
|
136
|
-
for the contact surface, and use the printed part as a holder that does not touch the sample.
|
|
137
|
-
- "Biocompatible" on a resin datasheet refers to a specific certified process and application. It
|
|
138
|
-
does not transfer to your printer, your cure schedule, or your assay. Say this rather than
|
|
139
|
-
implying a printed part is cell-safe.
|
|
140
|
-
|
|
141
|
-
### Optical
|
|
142
|
-
|
|
143
|
-
- Printed and milled surfaces scatter; they are not optical surfaces.
|
|
144
|
-
- Most printed resins **autofluoresce**, often strongly, which contaminates fluorescence readouts.
|
|
145
|
-
- Black is not automatically non-reflective.
|
|
146
|
-
- Where an optical surface is needed, use glass or a bonded film and model the holder around it.
|
|
147
|
-
|
|
148
|
-
## Cost and lead-time reality
|
|
149
|
-
|
|
150
|
-
Mention these when recommending a process: FDM is hours and pennies; SLA is hours and modest cost;
|
|
151
|
-
SLS and CNC are typically outsourced with days of lead time and much higher cost. A design that
|
|
152
|
-
needs ±0.05 mm has committed the user to CNC — flag that trade before they discover it at quoting.
|
|
153
|
-
|
|
154
|
-
## Before fabrication
|
|
155
|
-
|
|
156
|
-
Work through `references/validation.md`.
|