wwood-bioruby 1.2.11

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Files changed (386) hide show
  1. data/README.rdoc +205 -0
  2. data/README_DEV.rdoc +285 -0
  3. data/VERSION.yml +4 -0
  4. data/bin/bioruby +44 -0
  5. data/bin/br_biofetch.rb +47 -0
  6. data/bin/br_bioflat.rb +293 -0
  7. data/bin/br_biogetseq.rb +45 -0
  8. data/bin/br_pmfetch.rb +421 -0
  9. data/lib/bio.rb +306 -0
  10. data/lib/bio/alignment.rb +2518 -0
  11. data/lib/bio/appl/bl2seq/report.rb +334 -0
  12. data/lib/bio/appl/blast.rb +505 -0
  13. data/lib/bio/appl/blast/ddbj.rb +142 -0
  14. data/lib/bio/appl/blast/format0.rb +1438 -0
  15. data/lib/bio/appl/blast/format8.rb +83 -0
  16. data/lib/bio/appl/blast/genomenet.rb +263 -0
  17. data/lib/bio/appl/blast/ncbioptions.rb +220 -0
  18. data/lib/bio/appl/blast/remote.rb +105 -0
  19. data/lib/bio/appl/blast/report.rb +767 -0
  20. data/lib/bio/appl/blast/rexml.rb +144 -0
  21. data/lib/bio/appl/blast/rpsblast.rb +277 -0
  22. data/lib/bio/appl/blast/wublast.rb +635 -0
  23. data/lib/bio/appl/blast/xmlparser.rb +236 -0
  24. data/lib/bio/appl/blat/report.rb +530 -0
  25. data/lib/bio/appl/clustalw.rb +219 -0
  26. data/lib/bio/appl/clustalw/report.rb +152 -0
  27. data/lib/bio/appl/emboss.rb +203 -0
  28. data/lib/bio/appl/fasta.rb +235 -0
  29. data/lib/bio/appl/fasta/format10.rb +325 -0
  30. data/lib/bio/appl/gcg/msf.rb +212 -0
  31. data/lib/bio/appl/gcg/seq.rb +195 -0
  32. data/lib/bio/appl/genscan/report.rb +552 -0
  33. data/lib/bio/appl/hmmer.rb +126 -0
  34. data/lib/bio/appl/hmmer/report.rb +683 -0
  35. data/lib/bio/appl/iprscan/report.rb +374 -0
  36. data/lib/bio/appl/mafft.rb +259 -0
  37. data/lib/bio/appl/mafft/report.rb +226 -0
  38. data/lib/bio/appl/muscle.rb +52 -0
  39. data/lib/bio/appl/paml/baseml.rb +95 -0
  40. data/lib/bio/appl/paml/baseml/report.rb +32 -0
  41. data/lib/bio/appl/paml/codeml.rb +242 -0
  42. data/lib/bio/appl/paml/codeml/rates.rb +67 -0
  43. data/lib/bio/appl/paml/codeml/report.rb +67 -0
  44. data/lib/bio/appl/paml/common.rb +348 -0
  45. data/lib/bio/appl/paml/common_report.rb +38 -0
  46. data/lib/bio/appl/paml/yn00.rb +103 -0
  47. data/lib/bio/appl/paml/yn00/report.rb +32 -0
  48. data/lib/bio/appl/phylip/alignment.rb +133 -0
  49. data/lib/bio/appl/phylip/distance_matrix.rb +96 -0
  50. data/lib/bio/appl/probcons.rb +41 -0
  51. data/lib/bio/appl/psort.rb +548 -0
  52. data/lib/bio/appl/psort/report.rb +542 -0
  53. data/lib/bio/appl/pts1.rb +263 -0
  54. data/lib/bio/appl/sim4.rb +124 -0
  55. data/lib/bio/appl/sim4/report.rb +485 -0
  56. data/lib/bio/appl/sosui/report.rb +151 -0
  57. data/lib/bio/appl/spidey/report.rb +593 -0
  58. data/lib/bio/appl/targetp/report.rb +267 -0
  59. data/lib/bio/appl/tcoffee.rb +55 -0
  60. data/lib/bio/appl/tmhmm/report.rb +231 -0
  61. data/lib/bio/command.rb +593 -0
  62. data/lib/bio/compat/features.rb +157 -0
  63. data/lib/bio/compat/references.rb +128 -0
  64. data/lib/bio/data/aa.rb +353 -0
  65. data/lib/bio/data/codontable.rb +722 -0
  66. data/lib/bio/data/na.rb +223 -0
  67. data/lib/bio/db.rb +329 -0
  68. data/lib/bio/db/aaindex.rb +357 -0
  69. data/lib/bio/db/biosql/biosql_to_biosequence.rb +67 -0
  70. data/lib/bio/db/biosql/sequence.rb +508 -0
  71. data/lib/bio/db/embl/common.rb +352 -0
  72. data/lib/bio/db/embl/embl.rb +500 -0
  73. data/lib/bio/db/embl/embl_to_biosequence.rb +85 -0
  74. data/lib/bio/db/embl/format_embl.rb +190 -0
  75. data/lib/bio/db/embl/sptr.rb +1283 -0
  76. data/lib/bio/db/embl/swissprot.rb +42 -0
  77. data/lib/bio/db/embl/trembl.rb +41 -0
  78. data/lib/bio/db/embl/uniprot.rb +42 -0
  79. data/lib/bio/db/fantom.rb +597 -0
  80. data/lib/bio/db/fasta.rb +410 -0
  81. data/lib/bio/db/fasta/defline.rb +532 -0
  82. data/lib/bio/db/fasta/fasta_to_biosequence.rb +63 -0
  83. data/lib/bio/db/fasta/format_fasta.rb +97 -0
  84. data/lib/bio/db/genbank/common.rb +307 -0
  85. data/lib/bio/db/genbank/ddbj.rb +22 -0
  86. data/lib/bio/db/genbank/format_genbank.rb +187 -0
  87. data/lib/bio/db/genbank/genbank.rb +250 -0
  88. data/lib/bio/db/genbank/genbank_to_biosequence.rb +86 -0
  89. data/lib/bio/db/genbank/genpept.rb +60 -0
  90. data/lib/bio/db/genbank/refseq.rb +18 -0
  91. data/lib/bio/db/gff.rb +1846 -0
  92. data/lib/bio/db/go.rb +481 -0
  93. data/lib/bio/db/kegg/brite.rb +41 -0
  94. data/lib/bio/db/kegg/compound.rb +131 -0
  95. data/lib/bio/db/kegg/drug.rb +98 -0
  96. data/lib/bio/db/kegg/enzyme.rb +148 -0
  97. data/lib/bio/db/kegg/expression.rb +155 -0
  98. data/lib/bio/db/kegg/genes.rb +263 -0
  99. data/lib/bio/db/kegg/genome.rb +241 -0
  100. data/lib/bio/db/kegg/glycan.rb +166 -0
  101. data/lib/bio/db/kegg/keggtab.rb +357 -0
  102. data/lib/bio/db/kegg/kgml.rb +256 -0
  103. data/lib/bio/db/kegg/orthology.rb +136 -0
  104. data/lib/bio/db/kegg/reaction.rb +82 -0
  105. data/lib/bio/db/kegg/taxonomy.rb +331 -0
  106. data/lib/bio/db/lasergene.rb +209 -0
  107. data/lib/bio/db/litdb.rb +107 -0
  108. data/lib/bio/db/medline.rb +326 -0
  109. data/lib/bio/db/nbrf.rb +191 -0
  110. data/lib/bio/db/newick.rb +658 -0
  111. data/lib/bio/db/nexus.rb +1854 -0
  112. data/lib/bio/db/pdb.rb +29 -0
  113. data/lib/bio/db/pdb/atom.rb +77 -0
  114. data/lib/bio/db/pdb/chain.rb +210 -0
  115. data/lib/bio/db/pdb/chemicalcomponent.rb +224 -0
  116. data/lib/bio/db/pdb/model.rb +148 -0
  117. data/lib/bio/db/pdb/pdb.rb +1911 -0
  118. data/lib/bio/db/pdb/residue.rb +176 -0
  119. data/lib/bio/db/pdb/utils.rb +399 -0
  120. data/lib/bio/db/prosite.rb +597 -0
  121. data/lib/bio/db/rebase.rb +456 -0
  122. data/lib/bio/db/soft.rb +404 -0
  123. data/lib/bio/db/transfac.rb +375 -0
  124. data/lib/bio/db/url.rb +42 -0
  125. data/lib/bio/feature.rb +139 -0
  126. data/lib/bio/io/biosql/biodatabase.rb +64 -0
  127. data/lib/bio/io/biosql/bioentry.rb +29 -0
  128. data/lib/bio/io/biosql/bioentry_dbxref.rb +11 -0
  129. data/lib/bio/io/biosql/bioentry_path.rb +12 -0
  130. data/lib/bio/io/biosql/bioentry_qualifier_value.rb +10 -0
  131. data/lib/bio/io/biosql/bioentry_reference.rb +10 -0
  132. data/lib/bio/io/biosql/bioentry_relationship.rb +10 -0
  133. data/lib/bio/io/biosql/biosequence.rb +11 -0
  134. data/lib/bio/io/biosql/comment.rb +7 -0
  135. data/lib/bio/io/biosql/config/database.yml +20 -0
  136. data/lib/bio/io/biosql/dbxref.rb +13 -0
  137. data/lib/bio/io/biosql/dbxref_qualifier_value.rb +12 -0
  138. data/lib/bio/io/biosql/location.rb +32 -0
  139. data/lib/bio/io/biosql/location_qualifier_value.rb +11 -0
  140. data/lib/bio/io/biosql/ontology.rb +10 -0
  141. data/lib/bio/io/biosql/reference.rb +9 -0
  142. data/lib/bio/io/biosql/seqfeature.rb +32 -0
  143. data/lib/bio/io/biosql/seqfeature_dbxref.rb +11 -0
  144. data/lib/bio/io/biosql/seqfeature_path.rb +11 -0
  145. data/lib/bio/io/biosql/seqfeature_qualifier_value.rb +20 -0
  146. data/lib/bio/io/biosql/seqfeature_relationship.rb +11 -0
  147. data/lib/bio/io/biosql/taxon.rb +12 -0
  148. data/lib/bio/io/biosql/taxon_name.rb +9 -0
  149. data/lib/bio/io/biosql/term.rb +27 -0
  150. data/lib/bio/io/biosql/term_dbxref.rb +11 -0
  151. data/lib/bio/io/biosql/term_path.rb +12 -0
  152. data/lib/bio/io/biosql/term_relationship.rb +13 -0
  153. data/lib/bio/io/biosql/term_relationship_term.rb +11 -0
  154. data/lib/bio/io/biosql/term_synonym.rb +10 -0
  155. data/lib/bio/io/das.rb +461 -0
  156. data/lib/bio/io/dbget.rb +194 -0
  157. data/lib/bio/io/ddbjxml.rb +638 -0
  158. data/lib/bio/io/ebisoap.rb +158 -0
  159. data/lib/bio/io/ensembl.rb +229 -0
  160. data/lib/bio/io/fastacmd.rb +163 -0
  161. data/lib/bio/io/fetch.rb +195 -0
  162. data/lib/bio/io/flatfile.rb +482 -0
  163. data/lib/bio/io/flatfile/autodetection.rb +545 -0
  164. data/lib/bio/io/flatfile/bdb.rb +253 -0
  165. data/lib/bio/io/flatfile/buffer.rb +237 -0
  166. data/lib/bio/io/flatfile/index.rb +1381 -0
  167. data/lib/bio/io/flatfile/indexer.rb +805 -0
  168. data/lib/bio/io/flatfile/splitter.rb +297 -0
  169. data/lib/bio/io/higet.rb +73 -0
  170. data/lib/bio/io/hinv.rb +442 -0
  171. data/lib/bio/io/keggapi.rb +805 -0
  172. data/lib/bio/io/ncbirest.rb +733 -0
  173. data/lib/bio/io/ncbisoap.rb +155 -0
  174. data/lib/bio/io/pubmed.rb +307 -0
  175. data/lib/bio/io/registry.rb +292 -0
  176. data/lib/bio/io/soapwsdl.rb +119 -0
  177. data/lib/bio/io/sql.rb +186 -0
  178. data/lib/bio/location.rb +867 -0
  179. data/lib/bio/map.rb +410 -0
  180. data/lib/bio/pathway.rb +960 -0
  181. data/lib/bio/reference.rb +602 -0
  182. data/lib/bio/sequence.rb +456 -0
  183. data/lib/bio/sequence/aa.rb +152 -0
  184. data/lib/bio/sequence/adapter.rb +108 -0
  185. data/lib/bio/sequence/common.rb +310 -0
  186. data/lib/bio/sequence/compat.rb +123 -0
  187. data/lib/bio/sequence/dblink.rb +54 -0
  188. data/lib/bio/sequence/format.rb +358 -0
  189. data/lib/bio/sequence/format_raw.rb +23 -0
  190. data/lib/bio/sequence/generic.rb +24 -0
  191. data/lib/bio/sequence/na.rb +491 -0
  192. data/lib/bio/shell.rb +44 -0
  193. data/lib/bio/shell/core.rb +578 -0
  194. data/lib/bio/shell/demo.rb +146 -0
  195. data/lib/bio/shell/interface.rb +218 -0
  196. data/lib/bio/shell/irb.rb +95 -0
  197. data/lib/bio/shell/object.rb +71 -0
  198. data/lib/bio/shell/plugin/blast.rb +42 -0
  199. data/lib/bio/shell/plugin/codon.rb +218 -0
  200. data/lib/bio/shell/plugin/das.rb +58 -0
  201. data/lib/bio/shell/plugin/emboss.rb +23 -0
  202. data/lib/bio/shell/plugin/entry.rb +105 -0
  203. data/lib/bio/shell/plugin/flatfile.rb +101 -0
  204. data/lib/bio/shell/plugin/keggapi.rb +181 -0
  205. data/lib/bio/shell/plugin/midi.rb +430 -0
  206. data/lib/bio/shell/plugin/obda.rb +45 -0
  207. data/lib/bio/shell/plugin/psort.rb +56 -0
  208. data/lib/bio/shell/plugin/seq.rb +247 -0
  209. data/lib/bio/shell/plugin/soap.rb +87 -0
  210. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/bioruby_generator.rb +29 -0
  211. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/_classes.rhtml +4 -0
  212. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/_log.rhtml +27 -0
  213. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/_methods.rhtml +11 -0
  214. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/_modules.rhtml +4 -0
  215. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/_variables.rhtml +7 -0
  216. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby-bg.gif +0 -0
  217. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby-gem.png +0 -0
  218. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby-link.gif +0 -0
  219. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby.css +368 -0
  220. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby.rhtml +47 -0
  221. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby_controller.rb +144 -0
  222. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby_helper.rb +47 -0
  223. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/commands.rhtml +8 -0
  224. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/history.rhtml +10 -0
  225. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/index.rhtml +26 -0
  226. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/spinner.gif +0 -0
  227. data/lib/bio/shell/script.rb +25 -0
  228. data/lib/bio/shell/setup.rb +109 -0
  229. data/lib/bio/shell/web.rb +102 -0
  230. data/lib/bio/tree.rb +852 -0
  231. data/lib/bio/util/color_scheme.rb +191 -0
  232. data/lib/bio/util/color_scheme/buried.rb +59 -0
  233. data/lib/bio/util/color_scheme/helix.rb +59 -0
  234. data/lib/bio/util/color_scheme/hydropathy.rb +64 -0
  235. data/lib/bio/util/color_scheme/nucleotide.rb +31 -0
  236. data/lib/bio/util/color_scheme/strand.rb +59 -0
  237. data/lib/bio/util/color_scheme/taylor.rb +50 -0
  238. data/lib/bio/util/color_scheme/turn.rb +59 -0
  239. data/lib/bio/util/color_scheme/zappo.rb +50 -0
  240. data/lib/bio/util/contingency_table.rb +370 -0
  241. data/lib/bio/util/restriction_enzyme.rb +228 -0
  242. data/lib/bio/util/restriction_enzyme/analysis.rb +249 -0
  243. data/lib/bio/util/restriction_enzyme/analysis_basic.rb +217 -0
  244. data/lib/bio/util/restriction_enzyme/cut_symbol.rb +107 -0
  245. data/lib/bio/util/restriction_enzyme/double_stranded.rb +321 -0
  246. data/lib/bio/util/restriction_enzyme/double_stranded/aligned_strands.rb +130 -0
  247. data/lib/bio/util/restriction_enzyme/double_stranded/cut_location_pair.rb +103 -0
  248. data/lib/bio/util/restriction_enzyme/double_stranded/cut_location_pair_in_enzyme_notation.rb +38 -0
  249. data/lib/bio/util/restriction_enzyme/double_stranded/cut_locations.rb +76 -0
  250. data/lib/bio/util/restriction_enzyme/double_stranded/cut_locations_in_enzyme_notation.rb +107 -0
  251. data/lib/bio/util/restriction_enzyme/enzymes.yaml +7061 -0
  252. data/lib/bio/util/restriction_enzyme/range/cut_range.rb +24 -0
  253. data/lib/bio/util/restriction_enzyme/range/cut_ranges.rb +47 -0
  254. data/lib/bio/util/restriction_enzyme/range/horizontal_cut_range.rb +67 -0
  255. data/lib/bio/util/restriction_enzyme/range/sequence_range.rb +257 -0
  256. data/lib/bio/util/restriction_enzyme/range/sequence_range/calculated_cuts.rb +242 -0
  257. data/lib/bio/util/restriction_enzyme/range/sequence_range/fragment.rb +51 -0
  258. data/lib/bio/util/restriction_enzyme/range/sequence_range/fragments.rb +41 -0
  259. data/lib/bio/util/restriction_enzyme/range/vertical_cut_range.rb +77 -0
  260. data/lib/bio/util/restriction_enzyme/single_strand.rb +200 -0
  261. data/lib/bio/util/restriction_enzyme/single_strand/cut_locations_in_enzyme_notation.rb +135 -0
  262. data/lib/bio/util/restriction_enzyme/single_strand_complement.rb +23 -0
  263. data/lib/bio/util/restriction_enzyme/string_formatting.rb +111 -0
  264. data/lib/bio/util/sirna.rb +288 -0
  265. data/test/data/HMMER/hmmpfam.out +64 -0
  266. data/test/data/HMMER/hmmsearch.out +88 -0
  267. data/test/data/SOSUI/sample.report +11 -0
  268. data/test/data/TMHMM/sample.report +21 -0
  269. data/test/data/aaindex/DAYM780301 +30 -0
  270. data/test/data/aaindex/PRAM900102 +20 -0
  271. data/test/data/bl2seq/cd8a_cd8b_blastp.bl2seq +53 -0
  272. data/test/data/bl2seq/cd8a_p53_e-5blastp.bl2seq +37 -0
  273. data/test/data/blast/2.2.15.blastp.m7 +876 -0
  274. data/test/data/blast/b0002.faa +15 -0
  275. data/test/data/blast/b0002.faa.m0 +128 -0
  276. data/test/data/blast/b0002.faa.m7 +65 -0
  277. data/test/data/blast/b0002.faa.m8 +1 -0
  278. data/test/data/blast/blastp-multi.m7 +188 -0
  279. data/test/data/command/echoarg2.bat +1 -0
  280. data/test/data/embl/AB090716.embl +65 -0
  281. data/test/data/embl/AB090716.embl.rel89 +63 -0
  282. data/test/data/fasta/example1.txt +75 -0
  283. data/test/data/fasta/example2.txt +21 -0
  284. data/test/data/genscan/sample.report +63 -0
  285. data/test/data/iprscan/merged.raw +32 -0
  286. data/test/data/iprscan/merged.txt +74 -0
  287. data/test/data/paml/codeml/control_file.txt +30 -0
  288. data/test/data/paml/codeml/output.txt +78 -0
  289. data/test/data/paml/codeml/rates +217 -0
  290. data/test/data/prosite/prosite.dat +2233 -0
  291. data/test/data/refseq/nm_126355.entret +64 -0
  292. data/test/data/rpsblast/misc.rpsblast +193 -0
  293. data/test/data/soft/GDS100_partial.soft +92 -0
  294. data/test/data/soft/GSE3457_family_partial.soft +874 -0
  295. data/test/data/uniprot/p53_human.uniprot +1456 -0
  296. data/test/functional/bio/appl/test_pts1.rb +115 -0
  297. data/test/functional/bio/io/test_ensembl.rb +229 -0
  298. data/test/functional/bio/io/test_soapwsdl.rb +52 -0
  299. data/test/functional/bio/sequence/test_output_embl.rb +51 -0
  300. data/test/functional/bio/test_command.rb +301 -0
  301. data/test/runner.rb +14 -0
  302. data/test/unit/bio/appl/bl2seq/test_report.rb +134 -0
  303. data/test/unit/bio/appl/blast/test_ncbioptions.rb +112 -0
  304. data/test/unit/bio/appl/blast/test_report.rb +1135 -0
  305. data/test/unit/bio/appl/blast/test_rpsblast.rb +398 -0
  306. data/test/unit/bio/appl/genscan/test_report.rb +182 -0
  307. data/test/unit/bio/appl/hmmer/test_report.rb +342 -0
  308. data/test/unit/bio/appl/iprscan/test_report.rb +338 -0
  309. data/test/unit/bio/appl/mafft/test_report.rb +63 -0
  310. data/test/unit/bio/appl/paml/codeml/test_rates.rb +45 -0
  311. data/test/unit/bio/appl/paml/codeml/test_report.rb +45 -0
  312. data/test/unit/bio/appl/paml/test_codeml.rb +174 -0
  313. data/test/unit/bio/appl/sosui/test_report.rb +81 -0
  314. data/test/unit/bio/appl/targetp/test_report.rb +146 -0
  315. data/test/unit/bio/appl/test_blast.rb +277 -0
  316. data/test/unit/bio/appl/test_fasta.rb +130 -0
  317. data/test/unit/bio/appl/test_psort.rb +57 -0
  318. data/test/unit/bio/appl/test_pts1.rb +77 -0
  319. data/test/unit/bio/appl/tmhmm/test_report.rb +126 -0
  320. data/test/unit/bio/data/test_aa.rb +90 -0
  321. data/test/unit/bio/data/test_codontable.rb +107 -0
  322. data/test/unit/bio/data/test_na.rb +80 -0
  323. data/test/unit/bio/db/embl/test_common.rb +117 -0
  324. data/test/unit/bio/db/embl/test_embl.rb +214 -0
  325. data/test/unit/bio/db/embl/test_embl_rel89.rb +219 -0
  326. data/test/unit/bio/db/embl/test_embl_to_bioseq.rb +203 -0
  327. data/test/unit/bio/db/embl/test_sptr.rb +1812 -0
  328. data/test/unit/bio/db/embl/test_uniprot.rb +31 -0
  329. data/test/unit/bio/db/kegg/test_genes.rb +45 -0
  330. data/test/unit/bio/db/pdb/test_pdb.rb +152 -0
  331. data/test/unit/bio/db/test_aaindex.rb +197 -0
  332. data/test/unit/bio/db/test_fasta.rb +250 -0
  333. data/test/unit/bio/db/test_gff.rb +1190 -0
  334. data/test/unit/bio/db/test_lasergene.rb +95 -0
  335. data/test/unit/bio/db/test_medline.rb +127 -0
  336. data/test/unit/bio/db/test_newick.rb +293 -0
  337. data/test/unit/bio/db/test_nexus.rb +364 -0
  338. data/test/unit/bio/db/test_prosite.rb +1437 -0
  339. data/test/unit/bio/db/test_rebase.rb +101 -0
  340. data/test/unit/bio/db/test_soft.rb +138 -0
  341. data/test/unit/bio/db/test_url.rb +36 -0
  342. data/test/unit/bio/io/flatfile/test_autodetection.rb +375 -0
  343. data/test/unit/bio/io/flatfile/test_buffer.rb +251 -0
  344. data/test/unit/bio/io/flatfile/test_splitter.rb +369 -0
  345. data/test/unit/bio/io/test_ddbjxml.rb +80 -0
  346. data/test/unit/bio/io/test_ensembl.rb +109 -0
  347. data/test/unit/bio/io/test_fastacmd.rb +42 -0
  348. data/test/unit/bio/io/test_flatfile.rb +505 -0
  349. data/test/unit/bio/io/test_soapwsdl.rb +32 -0
  350. data/test/unit/bio/sequence/test_aa.rb +115 -0
  351. data/test/unit/bio/sequence/test_common.rb +373 -0
  352. data/test/unit/bio/sequence/test_compat.rb +69 -0
  353. data/test/unit/bio/sequence/test_dblink.rb +58 -0
  354. data/test/unit/bio/sequence/test_na.rb +330 -0
  355. data/test/unit/bio/shell/plugin/test_seq.rb +185 -0
  356. data/test/unit/bio/test_alignment.rb +1025 -0
  357. data/test/unit/bio/test_command.rb +349 -0
  358. data/test/unit/bio/test_db.rb +96 -0
  359. data/test/unit/bio/test_feature.rb +144 -0
  360. data/test/unit/bio/test_location.rb +599 -0
  361. data/test/unit/bio/test_map.rb +230 -0
  362. data/test/unit/bio/test_pathway.rb +499 -0
  363. data/test/unit/bio/test_reference.rb +252 -0
  364. data/test/unit/bio/test_sequence.rb +329 -0
  365. data/test/unit/bio/test_shell.rb +18 -0
  366. data/test/unit/bio/test_tree.rb +593 -0
  367. data/test/unit/bio/util/restriction_enzyme/analysis/test_calculated_cuts.rb +299 -0
  368. data/test/unit/bio/util/restriction_enzyme/analysis/test_cut_ranges.rb +103 -0
  369. data/test/unit/bio/util/restriction_enzyme/analysis/test_sequence_range.rb +240 -0
  370. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_aligned_strands.rb +101 -0
  371. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_location_pair.rb +75 -0
  372. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_location_pair_in_enzyme_notation.rb +73 -0
  373. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_locations.rb +53 -0
  374. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_locations_in_enzyme_notation.rb +104 -0
  375. data/test/unit/bio/util/restriction_enzyme/single_strand/test_cut_locations_in_enzyme_notation.rb +83 -0
  376. data/test/unit/bio/util/restriction_enzyme/test_analysis.rb +246 -0
  377. data/test/unit/bio/util/restriction_enzyme/test_cut_symbol.rb +44 -0
  378. data/test/unit/bio/util/restriction_enzyme/test_double_stranded.rb +115 -0
  379. data/test/unit/bio/util/restriction_enzyme/test_single_strand.rb +147 -0
  380. data/test/unit/bio/util/restriction_enzyme/test_single_strand_complement.rb +147 -0
  381. data/test/unit/bio/util/restriction_enzyme/test_string_formatting.rb +60 -0
  382. data/test/unit/bio/util/test_color_scheme.rb +33 -0
  383. data/test/unit/bio/util/test_contingency_table.rb +94 -0
  384. data/test/unit/bio/util/test_restriction_enzyme.rb +42 -0
  385. data/test/unit/bio/util/test_sirna.rb +245 -0
  386. metadata +543 -0
@@ -0,0 +1,205 @@
1
+ Copyright (C) 2001-2007 Toshiaki Katayama <k@bioruby.org>
2
+ 2008 Jan Aerts <jandot@bioruby.org>
3
+
4
+ = BioRuby
5
+
6
+ BioRuby is an open source Ruby library for developing bioinformatics
7
+ software. Object oriented scripting language Ruby has many features
8
+ suitable for bioinformatics research, for example, clear syntax to
9
+ express complex objects, regular expressions for text handling as
10
+ powerful as Perl's, a wide variety of libraries including web service
11
+ etc. As the syntax of the Ruby language is simple and very clean, we
12
+ believe that it is easy to learn for beginners, easy to use for
13
+ biologists, and also powerful enough for the software developers.
14
+
15
+ In BioRuby, you can retrieve biological database entries from flat
16
+ files, internet web servers and local relational databases. These
17
+ database entries can be parsed to extract information you need.
18
+ Biological sequences can be treated with the fulfilling methods of the
19
+ Ruby's String class and with regular expressions. Daily tools like
20
+ Blast, Fasta, Hmmer and many other software packages for biological
21
+ analysis can be executed within the BioRuby script, and the results
22
+ can be fully parsed to extract the portion you need. BioRuby supports
23
+ major biological database formats and provides many ways for accessing
24
+ them through flatfile indexing, SQL, web services etc. Various web
25
+ services including KEGG API can be easily utilized by BioRuby.
26
+
27
+
28
+ == FOR MORE INFORMATION
29
+
30
+ BioRuby's official website is at ((<URL:http://bioruby.org/>)).
31
+ You will find links to related resources including downloads,
32
+ mailing lists, Wiki documentation etc. in the top page.
33
+
34
+ * ((<URL:http://bioruby.org/>))
35
+
36
+
37
+ == WHERE TO OBTAIN
38
+
39
+ --- WWW
40
+
41
+ The stable release is freely available from the BioRuby website.
42
+
43
+ * ((<URL:http://bioruby.org/archive/>))
44
+
45
+ --- git
46
+
47
+ If you need the latest development version, this is provided at
48
+
49
+ * ((<URL:http://github.com/bioruby/bioruby>))
50
+
51
+ and can be obtained by the following procedure:
52
+
53
+ % git clone git://github.com/bioruby/bioruby.git
54
+
55
+ --- CVS
56
+
57
+ CVS is now deprecated as source control has moved to github. Please use git
58
+ instead of CVS. For historical purposes: the anonymous CVS was provided at
59
+
60
+ * ((<URL:http://cvs.bioruby.org/>))
61
+
62
+ and could be obtained by the following procedure.
63
+
64
+ % cvs -d :pserver:cvs@code.open-bio.org:/home/repository/bioruby login
65
+ CVS password: cvs (login with a password 'cvs' for the first time)
66
+ % cvs -d :pserver:cvs@code.open-bio.org:/home/repository/bioruby co bioruby
67
+
68
+ --- RubyGems
69
+
70
+ ((<RubyGems|URL:http://rubyforge.org/projects/rubygems/>)) version of
71
+ the BioRuby package is also available for easy installation.
72
+
73
+ * ((<URL:http://rubyforge.org/projects/bioruby/>))
74
+
75
+
76
+ == REQUIREMENTS
77
+
78
+ * Ruby 1.8.2 or later -- ((<URL:http://www.ruby-lang.org/>))
79
+ (Ruby 1.8.5 or later is recommended)
80
+
81
+ == OPTIONAL REQUIREMENTS
82
+
83
+ Some optional libraries can be utilized to extend BioRuby's functionality.
84
+ If your needs meets the following conditions, install them from the "Ruby
85
+ Application Archive" at ((<URL:http://raa.ruby-lang.org/>)).
86
+
87
+ For faster parsing of the BLAST XML output format:
88
+
89
+ * [RAA:xmlparser]
90
+
91
+ Creating faster flatfile index using Berkley DB:
92
+
93
+ * [RAA:bdb]
94
+
95
+ Accessing BioSQL database created by other Open Bio* libraries:
96
+
97
+ * ActiveRecord ((<URL:http://rubyforge.org/projects/activerecord/>))
98
+ and at least one driver (or adapter) from MySQL/Ruby
99
+ ((<URL:http://rubyforge.org/projects/mysql-ruby/>)),
100
+ postgres-pr ((<URL:http://rubyforge.org/projects/postgres-pr>)),
101
+ or ActiveRecord Oracle enhanced adapter
102
+ ((<URL:http://rubyforge.org/projects/oracle-enhanced/>)).
103
+ * For BioRuby 1.2.1 or older version, Ruby/DBI
104
+ ((<URL:http://rubyforge.org/projects/ruby-dbi>) and
105
+ at least one driver from MySQL/Ruby, postgres-pr, or
106
+ ruby-oci8 ((<URL:http://http://ruby-oci8.rubyforge.org/>))
107
+ (note that ruby-oci8 can only work with ruby-dbi 0.2.2).
108
+
109
+
110
+ == INSTALL
111
+
112
+ In the bioruby source directory (such as bioruby-x.x.x/), run setup.rb
113
+ as follows:
114
+
115
+ % su
116
+ # ruby setup.rb
117
+
118
+ These simple step installs this program under the default location of
119
+ Ruby libraries. You can also install files into your favorite directory
120
+ by supplying setup.rb some options. Try "ruby setup.rb --help".
121
+
122
+ If your operating system supports 'sudo' command (such as Mac OS X),
123
+ try the following procedure instead of the above.
124
+
125
+ % sudo ruby setup.rb
126
+
127
+ For older version users: "install.rb" is now renamed to "setup.rb".
128
+ The options "config", "setup", and "install" are still available.
129
+
130
+ % ruby setup.rb config
131
+ % ruby setup.rb setup
132
+ % su
133
+ # ruby setup.rb install
134
+
135
+ You can run tests by
136
+
137
+ % ruby setup.rb test
138
+
139
+ and run
140
+
141
+ % ruby setup.rb --help
142
+
143
+ for more details.
144
+
145
+ --- RubyGems
146
+
147
+ If you are using RubyGems, just type
148
+
149
+ % gems install bio
150
+
151
+
152
+ == SETUP
153
+
154
+ If you want to use the OBDA (Open Bio Database Access) to obtain database
155
+ entries, copy a sample configuration file in the BioRuby distribution
156
+
157
+ bioruby-x.x.x/etc/bioinformatics/seqdatabase.ini
158
+
159
+ to
160
+
161
+ /etc/bioinformatics/seqdatabase.ini (system wide configuration)
162
+
163
+ or
164
+
165
+ ~/.bioinformatics/seqdatabase.ini (personal configuration)
166
+
167
+ and change the contents according to your preference. For more
168
+ information on the OBDA, see ((<URL:http://obda.open-bio.org/>)).
169
+
170
+
171
+ == USAGE
172
+
173
+ You can load all BioRuby classes just by requiring 'bio.rb'. All the
174
+ BioRuby classes and modules are located under the module name 'Bio' to
175
+ separate the name space.
176
+
177
+ #!/usr/bin/env ruby
178
+ require 'bio'
179
+
180
+ You can also read other documentation in the 'doc' directory.
181
+
182
+ bioruby-x.x.x/doc/
183
+
184
+ --- RubyGems
185
+
186
+ With RubyGems, you need to load 'rubygems' library before using 'bio'.
187
+
188
+ #!/usr/bin/env ruby
189
+ require 'rubygems'
190
+ require_gem 'bio'
191
+
192
+
193
+ == LICENSE
194
+
195
+ BioRuby can be freely distributed under the same terms as Ruby.
196
+
197
+ Note that setup.rb included in the BioRuby package comes from
198
+ [RAA:setup] developed by Minero Aoki.
199
+
200
+
201
+ == CONTACT
202
+
203
+ Current staff of the BioRuby project can be reached by sending e-mail
204
+ to <staff@bioruby.org>.
205
+
@@ -0,0 +1,285 @@
1
+ = README.DEV
2
+
3
+ Copyright:: Copyright (C) 2005, 2006 Toshiaki Katayama <k@bioruby.org>
4
+ Copyright:: Copyright (C) 2006, 2008 Jan Aerts <jandot@bioruby.org>
5
+
6
+ = HOW TO CONTRIBUTE TO THE BIORUBY PROJECT?
7
+
8
+ There are many possible ways to contribute to the BioRuby project,
9
+ such as:
10
+
11
+ * Join the discussion on the BioRuby mailing list
12
+ * Send a bug report or write a bug fix patch
13
+ * Add and correct documentation
14
+ * Develop code for new features, etc.
15
+
16
+ All of these are welcome! However, this document describes the last option,
17
+ how to contribute your code to the BioRuby distribution.
18
+
19
+ We would like to include your contribution as long as the scope of
20
+ your module meets the field of bioinformatics.
21
+
22
+ == Git
23
+
24
+ Bioruby is now under git source control at http://github.com/bioruby/bioruby.
25
+ There are two basic ways to contribute: with patches or pull requests. Both are
26
+ explained on the bioruby wiki at http://bioruby.open-bio.org/wiki.
27
+
28
+ = LICENSE
29
+
30
+ If you would like your module to be included in the BioRuby distribution,
31
+ you need to give us right to change the license of your module to make it
32
+ compatible with other modules in BioRuby.
33
+
34
+ BioRuby was previously distributed under the LGPL license, but now is
35
+ distributed under the same terms as Ruby.
36
+
37
+ = CODING STYLE
38
+
39
+ You will need to follow the typical coding styles of the BioRuby modules:
40
+
41
+ == Use the following naming conventions
42
+
43
+ * CamelCase for module and class names
44
+ * '_'-separated_lowercase for method names
45
+ * '_'-separated_lowercase for variable names
46
+ * all UPPERCASE for constants
47
+
48
+ == Indentation must not include tabs
49
+
50
+ * Use 2 spaces for indentation.
51
+ * Don't replace spaces to tabs.
52
+
53
+ == Comments
54
+
55
+ Don't use <tt>=begin</tt> and <tt>=end</tt> blocks for comments. If you need to
56
+ add comments, include it in the RDoc documentation.
57
+
58
+ == Documentation should be written in the RDoc format in the source code
59
+
60
+ The RDoc format is becoming the popular standard for Ruby documentation.
61
+ We are now in transition from the previously used RD format to the RDoc
62
+ format in API documentation.
63
+
64
+ Additional tutorial documentation and working examples are encouraged
65
+ with your contribution. You may use the header part of the file for
66
+ this purpose as demonstrated in the previous section.
67
+
68
+ == Standard documentation
69
+
70
+ === of files
71
+
72
+ Each file should start with a header, which covers the following topics:
73
+ * copyright
74
+ * license
75
+ * description of the file (_not_ the classes; see below)
76
+ * any references, if appropriate
77
+
78
+ The header should be formatted as follows:
79
+
80
+ #
81
+ # = bio/db/hoge.rb - Hoge database parser classes
82
+ #
83
+ # Copyright:: Copyright (C) 2001, 2003-2005 Bio R. Hacker <brh@example.org>,
84
+ # Copyright:: Copyright (C) 2006 Chem R. Hacker <crh@example.org>
85
+ #
86
+ # License:: The Ruby License
87
+ #
88
+ # == Description
89
+ #
90
+ # This file contains classes that implement an interface to the Hoge database.
91
+ #
92
+ # == References
93
+ #
94
+ # * Hoge F. et al., The Hoge database, Nucleic. Acid. Res. 123:100--123 (2030)
95
+ # * http://hoge.db/
96
+ #
97
+
98
+ require 'foo'
99
+
100
+ module Bio
101
+
102
+ autoload :Bar, 'bio/bar'
103
+
104
+ class Hoge
105
+ :
106
+ end # Hoge
107
+
108
+ end # Bio
109
+
110
+ === of classes and methods within those files
111
+
112
+ Classes and methods should be documented in a standardized format, as in the
113
+ following example (from lib/bio/sequence.rb):
114
+
115
+ # == Description
116
+ #
117
+ # Bio::Sequence objects represent annotated sequences in bioruby.
118
+ # A Bio::Sequence object is a wrapper around the actual sequence,
119
+ # represented as either a Bio::Sequence::NA or a Bio::Sequence::AA object.
120
+ # For most users, this encapsulation will be completely transparent.
121
+ # Bio::Sequence responds to all methods defined for Bio::Sequence::NA/AA
122
+ # objects using the same arguments and returning the same values (even though
123
+ # these methods are not documented specifically for Bio::Sequence).
124
+ #
125
+ # == Usage
126
+ #
127
+ # require 'bio'
128
+ #
129
+ # # Create a nucleic or amino acid sequence
130
+ # dna = Bio::Sequence.auto('atgcatgcATGCATGCAAAA')
131
+ # rna = Bio::Sequence.auto('augcaugcaugcaugcaaaa')
132
+ # aa = Bio::Sequence.auto('ACDEFGHIKLMNPQRSTVWYU')
133
+ #
134
+ # # Print in FASTA format
135
+ # puts dna.output(:fasta)
136
+ #
137
+ # # Print all codons
138
+ # dna.window_search(3,3) do |codon|
139
+ # puts codon
140
+ # end
141
+ #
142
+ class Sequence
143
+
144
+ # Create a new Bio::Sequence object
145
+ #
146
+ # s = Bio::Sequence.new('atgc')
147
+ # puts s # => 'atgc'
148
+ #
149
+ # Note that this method does not intialize the contained sequence
150
+ # as any kind of bioruby object, only as a simple string
151
+ #
152
+ # puts s.seq.class # => String
153
+ #
154
+ # See Bio::Sequence#na, Bio::Sequence#aa, and Bio::Sequence#auto
155
+ # for methods to transform the basic String of a just created
156
+ # Bio::Sequence object to a proper bioruby object
157
+ # ---
158
+ # *Arguments*:
159
+ # * (required) _str_: String or Bio::Sequence::NA/AA object
160
+ # *Returns*:: Bio::Sequence object
161
+ def initialize(str)
162
+ @seq = str
163
+ end
164
+
165
+ # The sequence identifier. For example, for a sequence
166
+ # of Genbank origin, this is the accession number.
167
+ attr_accessor :entry_id
168
+
169
+ # An Array of Bio::Feature objects
170
+ attr_accessor :features
171
+ end # Sequence
172
+
173
+ Preceding the class definition (<tt>class Sequence</tt>), there is at least a
174
+ description and a usage example. Please use the +Description+ and +Usage+
175
+ headings. If appropriate, refer to other classes that interact with or are
176
+ related to the class.
177
+
178
+ The code in the usage example should, if possible, be in a format that a user
179
+ can copy-and-paste into a new script to run. It should illustrate the most
180
+ important uses of the class. If possible and if it would not clutter up the
181
+ example too much, try to provide any input data directly into the usage example,
182
+ instead of refering to ARGV or ARGF for input.
183
+
184
+ dna = Bio::Sequence.auto('atgcatgcATGCATGCAAAA')
185
+
186
+ Otherwise, describe the input shortly, for example:
187
+
188
+ # input should be string consisting of nucleotides
189
+ dna = Bio::Sequence.auto(ARGF.read)
190
+
191
+ Methods should be preceded by a comment that describes what the method does,
192
+ including any relevant usage examples. (In contrast to the documentation for
193
+ the class itself, headings are not required.) In addition, any arguments should
194
+ be listed, as well as the type of thing that is returned by the method. The
195
+ format of this information is as follows:
196
+
197
+ # ---
198
+ # *Arguments*:
199
+ # * (required) _str_: String or Bio::Sequence::NA
200
+ # * (optional) _nr_: a number that means something
201
+ # *Returns*:: true or false
202
+
203
+ Attribute accessors can be preceded by a short description.
204
+
205
+ == Exception handling
206
+
207
+ Don't use
208
+
209
+ $stderr.puts "WARNING"
210
+
211
+ in your code. Instead, try to avoid printing error messages. For fatal errors,
212
+ use +raise+ with an appropriate message.
213
+
214
+ == Testing code should use 'test/unit'
215
+
216
+ Unit tests should come with your modules by which you can assure what
217
+ you meant to do with each method. The test code is useful to make
218
+ maintenance easy and ensure stability. The use of
219
+
220
+ if __FILE__ == $0
221
+
222
+ is deprecated.
223
+
224
+ == Using autoload
225
+
226
+ To quicken the initial load time we have replaced most of 'require' to
227
+ 'autoload' since BioRuby version 0.7. During this change, we have found
228
+ some tips:
229
+
230
+ You should not separate the same namespace into several files.
231
+
232
+ * For example, if you have separated definitions of the Bio::Foo
233
+ class into two files (e.g. 'bio/foo.rb' and 'bio/bar.rb'), you
234
+ need to resolve the dependencies (including the load order)
235
+ yourself.
236
+
237
+ * If you have a defined Bio::Foo in 'bio/foo.rb' and a defined
238
+ Bio::Foo::Bar in 'bio/foo/bar.rb' add the following line in the
239
+ 'bio/foo.rb' file:
240
+
241
+ autoload :Bar, 'bio/foo/bar'
242
+
243
+ You should not put several top level namespaces in one file.
244
+
245
+ * For example, if you have Bio::A, Bio::B and Bio::C in the file
246
+ 'bio/foo.rb', you need
247
+
248
+ autoload :A, 'bio/foo'
249
+ autoload :B, 'bio/foo'
250
+ autoload :C, 'bio/foo'
251
+
252
+ to load the module automatically (instead of require 'bio/foo').
253
+ In this case, you should put them under the new namespace like
254
+ Bio::Foo::A, Bio::Foo::B and Bio::Foo::C in the file 'bio/foo',
255
+ then use
256
+
257
+ autoload :Foo, 'bio/foo'
258
+
259
+ so autoload can be written in 1 line.
260
+
261
+ = NAMESPACE
262
+
263
+ Your module should be located under the top-level module Bio and put under
264
+ the 'bioruby/lib/bio' directory. The class/module names and the
265
+ file names should be short and descriptive.
266
+
267
+ There are already several sub directories in 'bioruby/lib':
268
+
269
+ bio/*.rb -- general and widely used basic classes
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+ bio/appl/ -- wrapper and parser for the external applications
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+ bio/data/ -- basic biological data
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+ bio/db/ -- flatfile database entry parsers
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+ bio/io/ -- I/O interfaces for files, RDB, web services etc.
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+ bio/util/ -- utilities and algorithms for bioinformatics
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+
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+ If your module doesn't match any of the above, please propose
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+ an appropriate directory name when you contribute. Please let the staff
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+ discuss on namespaces (class names), API (method names) before commiting
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+ a new module or making changes on existing modules.
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+
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+ = MAINTENANCE
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+
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+ Finally, please maintain the code you've contributed. Please let us know (on
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+ the bioruby list) before you commit, so that users can discuss on the change.
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+