wwood-bioruby 1.2.11

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Files changed (386) hide show
  1. data/README.rdoc +205 -0
  2. data/README_DEV.rdoc +285 -0
  3. data/VERSION.yml +4 -0
  4. data/bin/bioruby +44 -0
  5. data/bin/br_biofetch.rb +47 -0
  6. data/bin/br_bioflat.rb +293 -0
  7. data/bin/br_biogetseq.rb +45 -0
  8. data/bin/br_pmfetch.rb +421 -0
  9. data/lib/bio.rb +306 -0
  10. data/lib/bio/alignment.rb +2518 -0
  11. data/lib/bio/appl/bl2seq/report.rb +334 -0
  12. data/lib/bio/appl/blast.rb +505 -0
  13. data/lib/bio/appl/blast/ddbj.rb +142 -0
  14. data/lib/bio/appl/blast/format0.rb +1438 -0
  15. data/lib/bio/appl/blast/format8.rb +83 -0
  16. data/lib/bio/appl/blast/genomenet.rb +263 -0
  17. data/lib/bio/appl/blast/ncbioptions.rb +220 -0
  18. data/lib/bio/appl/blast/remote.rb +105 -0
  19. data/lib/bio/appl/blast/report.rb +767 -0
  20. data/lib/bio/appl/blast/rexml.rb +144 -0
  21. data/lib/bio/appl/blast/rpsblast.rb +277 -0
  22. data/lib/bio/appl/blast/wublast.rb +635 -0
  23. data/lib/bio/appl/blast/xmlparser.rb +236 -0
  24. data/lib/bio/appl/blat/report.rb +530 -0
  25. data/lib/bio/appl/clustalw.rb +219 -0
  26. data/lib/bio/appl/clustalw/report.rb +152 -0
  27. data/lib/bio/appl/emboss.rb +203 -0
  28. data/lib/bio/appl/fasta.rb +235 -0
  29. data/lib/bio/appl/fasta/format10.rb +325 -0
  30. data/lib/bio/appl/gcg/msf.rb +212 -0
  31. data/lib/bio/appl/gcg/seq.rb +195 -0
  32. data/lib/bio/appl/genscan/report.rb +552 -0
  33. data/lib/bio/appl/hmmer.rb +126 -0
  34. data/lib/bio/appl/hmmer/report.rb +683 -0
  35. data/lib/bio/appl/iprscan/report.rb +374 -0
  36. data/lib/bio/appl/mafft.rb +259 -0
  37. data/lib/bio/appl/mafft/report.rb +226 -0
  38. data/lib/bio/appl/muscle.rb +52 -0
  39. data/lib/bio/appl/paml/baseml.rb +95 -0
  40. data/lib/bio/appl/paml/baseml/report.rb +32 -0
  41. data/lib/bio/appl/paml/codeml.rb +242 -0
  42. data/lib/bio/appl/paml/codeml/rates.rb +67 -0
  43. data/lib/bio/appl/paml/codeml/report.rb +67 -0
  44. data/lib/bio/appl/paml/common.rb +348 -0
  45. data/lib/bio/appl/paml/common_report.rb +38 -0
  46. data/lib/bio/appl/paml/yn00.rb +103 -0
  47. data/lib/bio/appl/paml/yn00/report.rb +32 -0
  48. data/lib/bio/appl/phylip/alignment.rb +133 -0
  49. data/lib/bio/appl/phylip/distance_matrix.rb +96 -0
  50. data/lib/bio/appl/probcons.rb +41 -0
  51. data/lib/bio/appl/psort.rb +548 -0
  52. data/lib/bio/appl/psort/report.rb +542 -0
  53. data/lib/bio/appl/pts1.rb +263 -0
  54. data/lib/bio/appl/sim4.rb +124 -0
  55. data/lib/bio/appl/sim4/report.rb +485 -0
  56. data/lib/bio/appl/sosui/report.rb +151 -0
  57. data/lib/bio/appl/spidey/report.rb +593 -0
  58. data/lib/bio/appl/targetp/report.rb +267 -0
  59. data/lib/bio/appl/tcoffee.rb +55 -0
  60. data/lib/bio/appl/tmhmm/report.rb +231 -0
  61. data/lib/bio/command.rb +593 -0
  62. data/lib/bio/compat/features.rb +157 -0
  63. data/lib/bio/compat/references.rb +128 -0
  64. data/lib/bio/data/aa.rb +353 -0
  65. data/lib/bio/data/codontable.rb +722 -0
  66. data/lib/bio/data/na.rb +223 -0
  67. data/lib/bio/db.rb +329 -0
  68. data/lib/bio/db/aaindex.rb +357 -0
  69. data/lib/bio/db/biosql/biosql_to_biosequence.rb +67 -0
  70. data/lib/bio/db/biosql/sequence.rb +508 -0
  71. data/lib/bio/db/embl/common.rb +352 -0
  72. data/lib/bio/db/embl/embl.rb +500 -0
  73. data/lib/bio/db/embl/embl_to_biosequence.rb +85 -0
  74. data/lib/bio/db/embl/format_embl.rb +190 -0
  75. data/lib/bio/db/embl/sptr.rb +1283 -0
  76. data/lib/bio/db/embl/swissprot.rb +42 -0
  77. data/lib/bio/db/embl/trembl.rb +41 -0
  78. data/lib/bio/db/embl/uniprot.rb +42 -0
  79. data/lib/bio/db/fantom.rb +597 -0
  80. data/lib/bio/db/fasta.rb +410 -0
  81. data/lib/bio/db/fasta/defline.rb +532 -0
  82. data/lib/bio/db/fasta/fasta_to_biosequence.rb +63 -0
  83. data/lib/bio/db/fasta/format_fasta.rb +97 -0
  84. data/lib/bio/db/genbank/common.rb +307 -0
  85. data/lib/bio/db/genbank/ddbj.rb +22 -0
  86. data/lib/bio/db/genbank/format_genbank.rb +187 -0
  87. data/lib/bio/db/genbank/genbank.rb +250 -0
  88. data/lib/bio/db/genbank/genbank_to_biosequence.rb +86 -0
  89. data/lib/bio/db/genbank/genpept.rb +60 -0
  90. data/lib/bio/db/genbank/refseq.rb +18 -0
  91. data/lib/bio/db/gff.rb +1846 -0
  92. data/lib/bio/db/go.rb +481 -0
  93. data/lib/bio/db/kegg/brite.rb +41 -0
  94. data/lib/bio/db/kegg/compound.rb +131 -0
  95. data/lib/bio/db/kegg/drug.rb +98 -0
  96. data/lib/bio/db/kegg/enzyme.rb +148 -0
  97. data/lib/bio/db/kegg/expression.rb +155 -0
  98. data/lib/bio/db/kegg/genes.rb +263 -0
  99. data/lib/bio/db/kegg/genome.rb +241 -0
  100. data/lib/bio/db/kegg/glycan.rb +166 -0
  101. data/lib/bio/db/kegg/keggtab.rb +357 -0
  102. data/lib/bio/db/kegg/kgml.rb +256 -0
  103. data/lib/bio/db/kegg/orthology.rb +136 -0
  104. data/lib/bio/db/kegg/reaction.rb +82 -0
  105. data/lib/bio/db/kegg/taxonomy.rb +331 -0
  106. data/lib/bio/db/lasergene.rb +209 -0
  107. data/lib/bio/db/litdb.rb +107 -0
  108. data/lib/bio/db/medline.rb +326 -0
  109. data/lib/bio/db/nbrf.rb +191 -0
  110. data/lib/bio/db/newick.rb +658 -0
  111. data/lib/bio/db/nexus.rb +1854 -0
  112. data/lib/bio/db/pdb.rb +29 -0
  113. data/lib/bio/db/pdb/atom.rb +77 -0
  114. data/lib/bio/db/pdb/chain.rb +210 -0
  115. data/lib/bio/db/pdb/chemicalcomponent.rb +224 -0
  116. data/lib/bio/db/pdb/model.rb +148 -0
  117. data/lib/bio/db/pdb/pdb.rb +1911 -0
  118. data/lib/bio/db/pdb/residue.rb +176 -0
  119. data/lib/bio/db/pdb/utils.rb +399 -0
  120. data/lib/bio/db/prosite.rb +597 -0
  121. data/lib/bio/db/rebase.rb +456 -0
  122. data/lib/bio/db/soft.rb +404 -0
  123. data/lib/bio/db/transfac.rb +375 -0
  124. data/lib/bio/db/url.rb +42 -0
  125. data/lib/bio/feature.rb +139 -0
  126. data/lib/bio/io/biosql/biodatabase.rb +64 -0
  127. data/lib/bio/io/biosql/bioentry.rb +29 -0
  128. data/lib/bio/io/biosql/bioentry_dbxref.rb +11 -0
  129. data/lib/bio/io/biosql/bioentry_path.rb +12 -0
  130. data/lib/bio/io/biosql/bioentry_qualifier_value.rb +10 -0
  131. data/lib/bio/io/biosql/bioentry_reference.rb +10 -0
  132. data/lib/bio/io/biosql/bioentry_relationship.rb +10 -0
  133. data/lib/bio/io/biosql/biosequence.rb +11 -0
  134. data/lib/bio/io/biosql/comment.rb +7 -0
  135. data/lib/bio/io/biosql/config/database.yml +20 -0
  136. data/lib/bio/io/biosql/dbxref.rb +13 -0
  137. data/lib/bio/io/biosql/dbxref_qualifier_value.rb +12 -0
  138. data/lib/bio/io/biosql/location.rb +32 -0
  139. data/lib/bio/io/biosql/location_qualifier_value.rb +11 -0
  140. data/lib/bio/io/biosql/ontology.rb +10 -0
  141. data/lib/bio/io/biosql/reference.rb +9 -0
  142. data/lib/bio/io/biosql/seqfeature.rb +32 -0
  143. data/lib/bio/io/biosql/seqfeature_dbxref.rb +11 -0
  144. data/lib/bio/io/biosql/seqfeature_path.rb +11 -0
  145. data/lib/bio/io/biosql/seqfeature_qualifier_value.rb +20 -0
  146. data/lib/bio/io/biosql/seqfeature_relationship.rb +11 -0
  147. data/lib/bio/io/biosql/taxon.rb +12 -0
  148. data/lib/bio/io/biosql/taxon_name.rb +9 -0
  149. data/lib/bio/io/biosql/term.rb +27 -0
  150. data/lib/bio/io/biosql/term_dbxref.rb +11 -0
  151. data/lib/bio/io/biosql/term_path.rb +12 -0
  152. data/lib/bio/io/biosql/term_relationship.rb +13 -0
  153. data/lib/bio/io/biosql/term_relationship_term.rb +11 -0
  154. data/lib/bio/io/biosql/term_synonym.rb +10 -0
  155. data/lib/bio/io/das.rb +461 -0
  156. data/lib/bio/io/dbget.rb +194 -0
  157. data/lib/bio/io/ddbjxml.rb +638 -0
  158. data/lib/bio/io/ebisoap.rb +158 -0
  159. data/lib/bio/io/ensembl.rb +229 -0
  160. data/lib/bio/io/fastacmd.rb +163 -0
  161. data/lib/bio/io/fetch.rb +195 -0
  162. data/lib/bio/io/flatfile.rb +482 -0
  163. data/lib/bio/io/flatfile/autodetection.rb +545 -0
  164. data/lib/bio/io/flatfile/bdb.rb +253 -0
  165. data/lib/bio/io/flatfile/buffer.rb +237 -0
  166. data/lib/bio/io/flatfile/index.rb +1381 -0
  167. data/lib/bio/io/flatfile/indexer.rb +805 -0
  168. data/lib/bio/io/flatfile/splitter.rb +297 -0
  169. data/lib/bio/io/higet.rb +73 -0
  170. data/lib/bio/io/hinv.rb +442 -0
  171. data/lib/bio/io/keggapi.rb +805 -0
  172. data/lib/bio/io/ncbirest.rb +733 -0
  173. data/lib/bio/io/ncbisoap.rb +155 -0
  174. data/lib/bio/io/pubmed.rb +307 -0
  175. data/lib/bio/io/registry.rb +292 -0
  176. data/lib/bio/io/soapwsdl.rb +119 -0
  177. data/lib/bio/io/sql.rb +186 -0
  178. data/lib/bio/location.rb +867 -0
  179. data/lib/bio/map.rb +410 -0
  180. data/lib/bio/pathway.rb +960 -0
  181. data/lib/bio/reference.rb +602 -0
  182. data/lib/bio/sequence.rb +456 -0
  183. data/lib/bio/sequence/aa.rb +152 -0
  184. data/lib/bio/sequence/adapter.rb +108 -0
  185. data/lib/bio/sequence/common.rb +310 -0
  186. data/lib/bio/sequence/compat.rb +123 -0
  187. data/lib/bio/sequence/dblink.rb +54 -0
  188. data/lib/bio/sequence/format.rb +358 -0
  189. data/lib/bio/sequence/format_raw.rb +23 -0
  190. data/lib/bio/sequence/generic.rb +24 -0
  191. data/lib/bio/sequence/na.rb +491 -0
  192. data/lib/bio/shell.rb +44 -0
  193. data/lib/bio/shell/core.rb +578 -0
  194. data/lib/bio/shell/demo.rb +146 -0
  195. data/lib/bio/shell/interface.rb +218 -0
  196. data/lib/bio/shell/irb.rb +95 -0
  197. data/lib/bio/shell/object.rb +71 -0
  198. data/lib/bio/shell/plugin/blast.rb +42 -0
  199. data/lib/bio/shell/plugin/codon.rb +218 -0
  200. data/lib/bio/shell/plugin/das.rb +58 -0
  201. data/lib/bio/shell/plugin/emboss.rb +23 -0
  202. data/lib/bio/shell/plugin/entry.rb +105 -0
  203. data/lib/bio/shell/plugin/flatfile.rb +101 -0
  204. data/lib/bio/shell/plugin/keggapi.rb +181 -0
  205. data/lib/bio/shell/plugin/midi.rb +430 -0
  206. data/lib/bio/shell/plugin/obda.rb +45 -0
  207. data/lib/bio/shell/plugin/psort.rb +56 -0
  208. data/lib/bio/shell/plugin/seq.rb +247 -0
  209. data/lib/bio/shell/plugin/soap.rb +87 -0
  210. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/bioruby_generator.rb +29 -0
  211. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/_classes.rhtml +4 -0
  212. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/_log.rhtml +27 -0
  213. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/_methods.rhtml +11 -0
  214. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/_modules.rhtml +4 -0
  215. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/_variables.rhtml +7 -0
  216. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby-bg.gif +0 -0
  217. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby-gem.png +0 -0
  218. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby-link.gif +0 -0
  219. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby.css +368 -0
  220. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby.rhtml +47 -0
  221. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby_controller.rb +144 -0
  222. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby_helper.rb +47 -0
  223. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/commands.rhtml +8 -0
  224. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/history.rhtml +10 -0
  225. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/index.rhtml +26 -0
  226. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/spinner.gif +0 -0
  227. data/lib/bio/shell/script.rb +25 -0
  228. data/lib/bio/shell/setup.rb +109 -0
  229. data/lib/bio/shell/web.rb +102 -0
  230. data/lib/bio/tree.rb +852 -0
  231. data/lib/bio/util/color_scheme.rb +191 -0
  232. data/lib/bio/util/color_scheme/buried.rb +59 -0
  233. data/lib/bio/util/color_scheme/helix.rb +59 -0
  234. data/lib/bio/util/color_scheme/hydropathy.rb +64 -0
  235. data/lib/bio/util/color_scheme/nucleotide.rb +31 -0
  236. data/lib/bio/util/color_scheme/strand.rb +59 -0
  237. data/lib/bio/util/color_scheme/taylor.rb +50 -0
  238. data/lib/bio/util/color_scheme/turn.rb +59 -0
  239. data/lib/bio/util/color_scheme/zappo.rb +50 -0
  240. data/lib/bio/util/contingency_table.rb +370 -0
  241. data/lib/bio/util/restriction_enzyme.rb +228 -0
  242. data/lib/bio/util/restriction_enzyme/analysis.rb +249 -0
  243. data/lib/bio/util/restriction_enzyme/analysis_basic.rb +217 -0
  244. data/lib/bio/util/restriction_enzyme/cut_symbol.rb +107 -0
  245. data/lib/bio/util/restriction_enzyme/double_stranded.rb +321 -0
  246. data/lib/bio/util/restriction_enzyme/double_stranded/aligned_strands.rb +130 -0
  247. data/lib/bio/util/restriction_enzyme/double_stranded/cut_location_pair.rb +103 -0
  248. data/lib/bio/util/restriction_enzyme/double_stranded/cut_location_pair_in_enzyme_notation.rb +38 -0
  249. data/lib/bio/util/restriction_enzyme/double_stranded/cut_locations.rb +76 -0
  250. data/lib/bio/util/restriction_enzyme/double_stranded/cut_locations_in_enzyme_notation.rb +107 -0
  251. data/lib/bio/util/restriction_enzyme/enzymes.yaml +7061 -0
  252. data/lib/bio/util/restriction_enzyme/range/cut_range.rb +24 -0
  253. data/lib/bio/util/restriction_enzyme/range/cut_ranges.rb +47 -0
  254. data/lib/bio/util/restriction_enzyme/range/horizontal_cut_range.rb +67 -0
  255. data/lib/bio/util/restriction_enzyme/range/sequence_range.rb +257 -0
  256. data/lib/bio/util/restriction_enzyme/range/sequence_range/calculated_cuts.rb +242 -0
  257. data/lib/bio/util/restriction_enzyme/range/sequence_range/fragment.rb +51 -0
  258. data/lib/bio/util/restriction_enzyme/range/sequence_range/fragments.rb +41 -0
  259. data/lib/bio/util/restriction_enzyme/range/vertical_cut_range.rb +77 -0
  260. data/lib/bio/util/restriction_enzyme/single_strand.rb +200 -0
  261. data/lib/bio/util/restriction_enzyme/single_strand/cut_locations_in_enzyme_notation.rb +135 -0
  262. data/lib/bio/util/restriction_enzyme/single_strand_complement.rb +23 -0
  263. data/lib/bio/util/restriction_enzyme/string_formatting.rb +111 -0
  264. data/lib/bio/util/sirna.rb +288 -0
  265. data/test/data/HMMER/hmmpfam.out +64 -0
  266. data/test/data/HMMER/hmmsearch.out +88 -0
  267. data/test/data/SOSUI/sample.report +11 -0
  268. data/test/data/TMHMM/sample.report +21 -0
  269. data/test/data/aaindex/DAYM780301 +30 -0
  270. data/test/data/aaindex/PRAM900102 +20 -0
  271. data/test/data/bl2seq/cd8a_cd8b_blastp.bl2seq +53 -0
  272. data/test/data/bl2seq/cd8a_p53_e-5blastp.bl2seq +37 -0
  273. data/test/data/blast/2.2.15.blastp.m7 +876 -0
  274. data/test/data/blast/b0002.faa +15 -0
  275. data/test/data/blast/b0002.faa.m0 +128 -0
  276. data/test/data/blast/b0002.faa.m7 +65 -0
  277. data/test/data/blast/b0002.faa.m8 +1 -0
  278. data/test/data/blast/blastp-multi.m7 +188 -0
  279. data/test/data/command/echoarg2.bat +1 -0
  280. data/test/data/embl/AB090716.embl +65 -0
  281. data/test/data/embl/AB090716.embl.rel89 +63 -0
  282. data/test/data/fasta/example1.txt +75 -0
  283. data/test/data/fasta/example2.txt +21 -0
  284. data/test/data/genscan/sample.report +63 -0
  285. data/test/data/iprscan/merged.raw +32 -0
  286. data/test/data/iprscan/merged.txt +74 -0
  287. data/test/data/paml/codeml/control_file.txt +30 -0
  288. data/test/data/paml/codeml/output.txt +78 -0
  289. data/test/data/paml/codeml/rates +217 -0
  290. data/test/data/prosite/prosite.dat +2233 -0
  291. data/test/data/refseq/nm_126355.entret +64 -0
  292. data/test/data/rpsblast/misc.rpsblast +193 -0
  293. data/test/data/soft/GDS100_partial.soft +92 -0
  294. data/test/data/soft/GSE3457_family_partial.soft +874 -0
  295. data/test/data/uniprot/p53_human.uniprot +1456 -0
  296. data/test/functional/bio/appl/test_pts1.rb +115 -0
  297. data/test/functional/bio/io/test_ensembl.rb +229 -0
  298. data/test/functional/bio/io/test_soapwsdl.rb +52 -0
  299. data/test/functional/bio/sequence/test_output_embl.rb +51 -0
  300. data/test/functional/bio/test_command.rb +301 -0
  301. data/test/runner.rb +14 -0
  302. data/test/unit/bio/appl/bl2seq/test_report.rb +134 -0
  303. data/test/unit/bio/appl/blast/test_ncbioptions.rb +112 -0
  304. data/test/unit/bio/appl/blast/test_report.rb +1135 -0
  305. data/test/unit/bio/appl/blast/test_rpsblast.rb +398 -0
  306. data/test/unit/bio/appl/genscan/test_report.rb +182 -0
  307. data/test/unit/bio/appl/hmmer/test_report.rb +342 -0
  308. data/test/unit/bio/appl/iprscan/test_report.rb +338 -0
  309. data/test/unit/bio/appl/mafft/test_report.rb +63 -0
  310. data/test/unit/bio/appl/paml/codeml/test_rates.rb +45 -0
  311. data/test/unit/bio/appl/paml/codeml/test_report.rb +45 -0
  312. data/test/unit/bio/appl/paml/test_codeml.rb +174 -0
  313. data/test/unit/bio/appl/sosui/test_report.rb +81 -0
  314. data/test/unit/bio/appl/targetp/test_report.rb +146 -0
  315. data/test/unit/bio/appl/test_blast.rb +277 -0
  316. data/test/unit/bio/appl/test_fasta.rb +130 -0
  317. data/test/unit/bio/appl/test_psort.rb +57 -0
  318. data/test/unit/bio/appl/test_pts1.rb +77 -0
  319. data/test/unit/bio/appl/tmhmm/test_report.rb +126 -0
  320. data/test/unit/bio/data/test_aa.rb +90 -0
  321. data/test/unit/bio/data/test_codontable.rb +107 -0
  322. data/test/unit/bio/data/test_na.rb +80 -0
  323. data/test/unit/bio/db/embl/test_common.rb +117 -0
  324. data/test/unit/bio/db/embl/test_embl.rb +214 -0
  325. data/test/unit/bio/db/embl/test_embl_rel89.rb +219 -0
  326. data/test/unit/bio/db/embl/test_embl_to_bioseq.rb +203 -0
  327. data/test/unit/bio/db/embl/test_sptr.rb +1812 -0
  328. data/test/unit/bio/db/embl/test_uniprot.rb +31 -0
  329. data/test/unit/bio/db/kegg/test_genes.rb +45 -0
  330. data/test/unit/bio/db/pdb/test_pdb.rb +152 -0
  331. data/test/unit/bio/db/test_aaindex.rb +197 -0
  332. data/test/unit/bio/db/test_fasta.rb +250 -0
  333. data/test/unit/bio/db/test_gff.rb +1190 -0
  334. data/test/unit/bio/db/test_lasergene.rb +95 -0
  335. data/test/unit/bio/db/test_medline.rb +127 -0
  336. data/test/unit/bio/db/test_newick.rb +293 -0
  337. data/test/unit/bio/db/test_nexus.rb +364 -0
  338. data/test/unit/bio/db/test_prosite.rb +1437 -0
  339. data/test/unit/bio/db/test_rebase.rb +101 -0
  340. data/test/unit/bio/db/test_soft.rb +138 -0
  341. data/test/unit/bio/db/test_url.rb +36 -0
  342. data/test/unit/bio/io/flatfile/test_autodetection.rb +375 -0
  343. data/test/unit/bio/io/flatfile/test_buffer.rb +251 -0
  344. data/test/unit/bio/io/flatfile/test_splitter.rb +369 -0
  345. data/test/unit/bio/io/test_ddbjxml.rb +80 -0
  346. data/test/unit/bio/io/test_ensembl.rb +109 -0
  347. data/test/unit/bio/io/test_fastacmd.rb +42 -0
  348. data/test/unit/bio/io/test_flatfile.rb +505 -0
  349. data/test/unit/bio/io/test_soapwsdl.rb +32 -0
  350. data/test/unit/bio/sequence/test_aa.rb +115 -0
  351. data/test/unit/bio/sequence/test_common.rb +373 -0
  352. data/test/unit/bio/sequence/test_compat.rb +69 -0
  353. data/test/unit/bio/sequence/test_dblink.rb +58 -0
  354. data/test/unit/bio/sequence/test_na.rb +330 -0
  355. data/test/unit/bio/shell/plugin/test_seq.rb +185 -0
  356. data/test/unit/bio/test_alignment.rb +1025 -0
  357. data/test/unit/bio/test_command.rb +349 -0
  358. data/test/unit/bio/test_db.rb +96 -0
  359. data/test/unit/bio/test_feature.rb +144 -0
  360. data/test/unit/bio/test_location.rb +599 -0
  361. data/test/unit/bio/test_map.rb +230 -0
  362. data/test/unit/bio/test_pathway.rb +499 -0
  363. data/test/unit/bio/test_reference.rb +252 -0
  364. data/test/unit/bio/test_sequence.rb +329 -0
  365. data/test/unit/bio/test_shell.rb +18 -0
  366. data/test/unit/bio/test_tree.rb +593 -0
  367. data/test/unit/bio/util/restriction_enzyme/analysis/test_calculated_cuts.rb +299 -0
  368. data/test/unit/bio/util/restriction_enzyme/analysis/test_cut_ranges.rb +103 -0
  369. data/test/unit/bio/util/restriction_enzyme/analysis/test_sequence_range.rb +240 -0
  370. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_aligned_strands.rb +101 -0
  371. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_location_pair.rb +75 -0
  372. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_location_pair_in_enzyme_notation.rb +73 -0
  373. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_locations.rb +53 -0
  374. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_locations_in_enzyme_notation.rb +104 -0
  375. data/test/unit/bio/util/restriction_enzyme/single_strand/test_cut_locations_in_enzyme_notation.rb +83 -0
  376. data/test/unit/bio/util/restriction_enzyme/test_analysis.rb +246 -0
  377. data/test/unit/bio/util/restriction_enzyme/test_cut_symbol.rb +44 -0
  378. data/test/unit/bio/util/restriction_enzyme/test_double_stranded.rb +115 -0
  379. data/test/unit/bio/util/restriction_enzyme/test_single_strand.rb +147 -0
  380. data/test/unit/bio/util/restriction_enzyme/test_single_strand_complement.rb +147 -0
  381. data/test/unit/bio/util/restriction_enzyme/test_string_formatting.rb +60 -0
  382. data/test/unit/bio/util/test_color_scheme.rb +33 -0
  383. data/test/unit/bio/util/test_contingency_table.rb +94 -0
  384. data/test/unit/bio/util/test_restriction_enzyme.rb +42 -0
  385. data/test/unit/bio/util/test_sirna.rb +245 -0
  386. metadata +543 -0
@@ -0,0 +1,155 @@
1
+ #
2
+ # = bio/io/ncbisoap.rb - SOAP interface for NCBI Entrez Utilities
3
+ #
4
+ # Copyright:: Copyright (C) 2004, 2006
5
+ # Toshiaki Katayama <k@bioruby.org>
6
+ # License:: The Ruby License
7
+ #
8
+ # $Id: ncbisoap.rb,v 1.3 2007/04/05 23:35:41 trevor Exp $
9
+ #
10
+
11
+ require 'bio/io/soapwsdl'
12
+
13
+ module Bio
14
+ class NCBI
15
+
16
+ # == References
17
+ #
18
+ # * http://eutils.ncbi.nlm.nih.gov/entrez/query/static/esoap_help.html
19
+ #
20
+ # == Methods
21
+ #
22
+ # All methods accept a hash as its argument and most of the keys can be
23
+ # ommited (values are string).
24
+ #
25
+ # Note: Methods which name ends with _MS are designed for use with
26
+ # Microsoft Visual Studio and SOAP Toolkit 3.0
27
+ #
28
+ # * http://www.ncbi.nlm.nih.gov/entrez/query/static/esoap_ms_help.html
29
+ #
30
+ # * run_eFetch(_MS)
31
+ # * "db", "id", "WebEnv", "query_key", "tool", "email", "retstart",
32
+ # "retmax", "rettype", "strand", "seq_start", "seq_stop", "complexity",
33
+ # "report"
34
+ #
35
+ # * run_eGquery(_MS)
36
+ # * "term", "tool", "email"
37
+ #
38
+ # * run_eInfo(_MS)
39
+ # * "db", "tool", "email"
40
+ #
41
+ # * run_eSpell(_MS)
42
+ # * "db", "term", "tool", "email"
43
+ #
44
+ # * run_eLink(_MS)
45
+ # * "db", "id", "reldate", "mindate", "maxdate", "datetype", "term"
46
+ # "dbfrom", "WebEnv", "query_key", "cmd", "tool", "email"
47
+ #
48
+ # * run_eSearch(_MS)
49
+ # * "db", "term", "WebEnv", "QueryKey", "usehistory", "tool", "email",
50
+ # "field", "reldate", "mindate", "maxdate", "datetype", "RetStart",
51
+ # "RetMax", "rettype", "sort"
52
+ #
53
+ # * run_eSummary(_MS)
54
+ # * "db", "id", "WebEnv", "query_key", "retstart", "retmax", "tool", "email"
55
+ #
56
+ # == Complex data types
57
+ #
58
+ # * http://www.ncbi.nlm.nih.gov/entrez/eutils/soap/egquery.xsd
59
+ # * http://www.ncbi.nlm.nih.gov/entrez/eutils/soap/einfo.xsd
60
+ # * http://www.ncbi.nlm.nih.gov/entrez/eutils/soap/esearch.xsd
61
+ # * http://www.ncbi.nlm.nih.gov/entrez/eutils/soap/esummary.xsd
62
+ # * http://www.ncbi.nlm.nih.gov/entrez/eutils/soap/elink.xsd
63
+ # * http://www.ncbi.nlm.nih.gov/entrez/eutils/soap/efetch.xsd
64
+ # * http://www.ncbi.nlm.nih.gov/entrez/eutils/soap/espell.xsd
65
+ #
66
+ class SOAP < Bio::SOAPWSDL
67
+
68
+ BASE_URI = "http://www.ncbi.nlm.nih.gov/entrez/eutils/soap/"
69
+
70
+ # set default to EUtils
71
+ SERVER_URI = BASE_URI + "eutils.wsdl"
72
+
73
+ def initialize(wsdl = nil)
74
+ super(wsdl || self.class::SERVER_URI)
75
+ end
76
+
77
+ def method_missing(*arg)
78
+ sleep 3 # make sure to rest for 3 seconds per request
79
+ @driver.send(*arg)
80
+ end
81
+
82
+ class EUtils < Bio::NCBI::SOAP
83
+ SERVER_URI = BASE_URI + "eutils.wsdl"
84
+ end
85
+
86
+ class EUtilsLite < Bio::NCBI::SOAP
87
+ SERVER_URI = BASE_URI + "eutils_lite.wsdl"
88
+ end
89
+
90
+ class EFetch < Bio::NCBI::SOAP
91
+ SERVER_URI = BASE_URI + "efetch.wsdl"
92
+ end
93
+
94
+ class EFetchLite < Bio::NCBI::SOAP
95
+ SERVER_URI = BASE_URI + "efetch_lit.wsdl"
96
+ end
97
+
98
+ end # SOAP
99
+ end # NCBI
100
+ end # Bio
101
+
102
+
103
+ if __FILE__ == $0
104
+
105
+ puts ">>> Bio::NCBI::SOAP::EFetch"
106
+ efetch = Bio::NCBI::SOAP::EFetch.new
107
+
108
+ puts "### run_eFetch in EFetch"
109
+ hash = {"db" => "protein", "id" => "37776955"}
110
+ result = efetch.run_eFetch(hash)
111
+ p result
112
+
113
+ puts ">>> Bio::NCBI::SOAP::EUtils"
114
+ eutils = Bio::NCBI::SOAP::EUtils.new
115
+
116
+ puts "### run_eFetch in EUtils"
117
+ hash = {"db" => "pubmed", "id" => "12345"}
118
+ result = eutils.run_eFetch(hash)
119
+ p result
120
+
121
+ puts "### run_eGquery - Entrez meta search to count hits in each DB"
122
+ hash = {"term" => "kinase"}
123
+ result = eutils.run_eGquery(hash) # working?
124
+ p result
125
+
126
+ puts "### run_eInfo - listing of the databases"
127
+ hash = {"db" => "protein"}
128
+ result = eutils.run_eInfo(hash)
129
+ p result
130
+
131
+ puts "### run_eSpell"
132
+ hash = {"db" => "pubmed", "term" => "kinas"}
133
+ result = eutils.run_eSpell(hash)
134
+ p result
135
+ p result["CorrectedQuery"]
136
+
137
+ puts "### run_eLink"
138
+ hash = {"db" => "protein", "id" => "37776955"}
139
+ result = eutils.run_eLink(hash) # working?
140
+ p result
141
+
142
+ puts "### run_eSearch"
143
+ hash = {"db" => "pubmed", "term" => "kinase"}
144
+ result = eutils.run_eSearch(hash)
145
+ p result
146
+
147
+ puts "### run_eSummary"
148
+ hash = {"db" => "protein", "id" => "37776955"}
149
+ result = eutils.run_eSummary(hash)
150
+ p result
151
+
152
+ end
153
+
154
+
155
+
@@ -0,0 +1,307 @@
1
+ #
2
+ # = bio/io/pubmed.rb - NCBI Entrez/PubMed client module
3
+ #
4
+ # Copyright:: Copyright (C) 2001, 2007, 2008 Toshiaki Katayama <k@bioruby.org>
5
+ # Copyright:: Copyright (C) 2006 Jan Aerts <jan.aerts@bbsrc.ac.uk>
6
+ # License:: The Ruby License
7
+ #
8
+ # $Id:$
9
+ #
10
+
11
+ require 'bio/io/ncbirest'
12
+ require 'bio/command'
13
+ require 'cgi'
14
+
15
+ module Bio
16
+
17
+ # == Description
18
+ #
19
+ # The Bio::PubMed class provides several ways to retrieve bibliographic
20
+ # information from the PubMed database at
21
+ # http://www.ncbi.nlm.nih.gov/sites/entrez?db=PubMed
22
+ #
23
+ # Basically, two types of queries are possible:
24
+ #
25
+ # * searching for PubMed IDs given a query string:
26
+ # * Bio::PubMed#esearch (recommended)
27
+ # * Bio::PubMed#search (only retrieves top 20 hits)
28
+ #
29
+ # * retrieving the MEDLINE text (i.e. authors, journal, abstract, ...)
30
+ # given a PubMed ID
31
+ # * Bio::PubMed#efetch (recommended)
32
+ # * Bio::PubMed#query (unstable for the change of the HTML design)
33
+ # * Bio::PubMed#pmfetch (still working but could be obsoleted by NCBI)
34
+ #
35
+ # The different methods within the same group are interchangeable and should
36
+ # return the same result.
37
+ #
38
+ # Additional information about the MEDLINE format and PubMed programmable
39
+ # APIs can be found on the following websites:
40
+ #
41
+ # * PubMed Overview:
42
+ # http://www.ncbi.nlm.nih.gov/entrez/query/static/overview.html
43
+ # * PubMed help:
44
+ # http://www.ncbi.nlm.nih.gov/entrez/query/static/help/pmhelp.html
45
+ # * Entrez utilities index:
46
+ # http://www.ncbi.nlm.nih.gov/entrez/utils/utils_index.html
47
+ # * How to link:
48
+ # http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=helplinks.chapter.linkshelp
49
+ #
50
+ # == Usage
51
+ #
52
+ # require 'bio'
53
+ #
54
+ # # If you don't know the pubmed ID:
55
+ # Bio::PubMed.esearch("(genome AND analysis) OR bioinformatics").each do |x|
56
+ # p x
57
+ # end
58
+ #
59
+ # Bio::PubMed.search("(genome AND analysis) OR bioinformatics").each do |x|
60
+ # p x
61
+ # end
62
+ #
63
+ # # To retrieve the MEDLINE entry for a given PubMed ID:
64
+ # puts Bio::PubMed.efetch("10592173", "14693808")
65
+ # puts Bio::PubMed.query("10592173")
66
+ # puts Bio::PubMed.pmfetch("10592173")
67
+ #
68
+ # # This can be converted into a Bio::MEDLINE object:
69
+ # manuscript = Bio::PubMed.query("10592173")
70
+ # medline = Bio::MEDLINE.new(manuscript)
71
+ #
72
+ class PubMed < Bio::NCBI::REST
73
+
74
+ # Search the PubMed database by given keywords using E-Utils and returns
75
+ # an array of PubMed IDs.
76
+ #
77
+ # For information on the possible arguments, see
78
+ # http://eutils.ncbi.nlm.nih.gov/entrez/query/static/esearch_help.html#PubMed
79
+ # ---
80
+ # *Arguments*:
81
+ # * _str_: query string (required)
82
+ # * _hash_: hash of E-Utils options
83
+ # * _retmode_: "xml", "html", ...
84
+ # * _rettype_: "medline", ...
85
+ # * _retmax_: integer (default 100)
86
+ # * _retstart_: integer
87
+ # * _field_
88
+ # * _reldate_
89
+ # * _mindate_
90
+ # * _maxdate_
91
+ # * _datetype_
92
+ # *Returns*:: array of PubMed IDs or a number of results
93
+ def esearch(str, hash = {})
94
+ opts = { "db" => "pubmed" }
95
+ opts.update(hash)
96
+ super(str, opts)
97
+ end
98
+
99
+ # Retrieve PubMed entry by PMID and returns MEDLINE formatted string using
100
+ # entrez efetch. Multiple PubMed IDs can be provided:
101
+ # Bio::PubMed.efetch(123)
102
+ # Bio::PubMed.efetch([123,456,789])
103
+ # ---
104
+ # *Arguments*:
105
+ # * _ids_: list of PubMed IDs (required)
106
+ # * _hash_: hash of E-Utils options
107
+ # * _retmode_: "xml", "html", ...
108
+ # * _rettype_: "medline", ...
109
+ # * _retmax_: integer (default 100)
110
+ # * _retstart_: integer
111
+ # * _field_
112
+ # * _reldate_
113
+ # * _mindate_
114
+ # * _maxdate_
115
+ # * _datetype_
116
+ # *Returns*:: Array of MEDLINE formatted String
117
+ def efetch(ids, hash = {})
118
+ opts = { "db" => "pubmed", "rettype" => "medline" }
119
+ opts.update(hash)
120
+ super(ids, opts)
121
+ end
122
+
123
+ # Search the PubMed database by given keywords using entrez query and returns
124
+ # an array of PubMed IDs. Caution: this method returns the first 20 hits only.
125
+ # Instead, use of the 'esearch' method is strongly recomended.
126
+ # ---
127
+ # *Arguments*:
128
+ # * _id_: query string (required)
129
+ # *Returns*:: array of PubMed IDs
130
+ def search(str)
131
+ host = "www.ncbi.nlm.nih.gov"
132
+ path = "/sites/entrez?tool=bioruby&cmd=Search&doptcmdl=Brief&db=PubMed&term="
133
+
134
+ ncbi_access_wait
135
+
136
+ http = Bio::Command.new_http(host)
137
+ response = http.get(path + CGI.escape(str))
138
+ result = response.body
139
+ result = result.scan(/value="(\d+)" id="UidCheckBox"/m).flatten
140
+ return result
141
+ end
142
+
143
+ # Retrieve PubMed entry by PMID and returns MEDLINE formatted string using
144
+ # entrez query.
145
+ # ---
146
+ # *Arguments*:
147
+ # * _id_: PubMed ID (required)
148
+ # *Returns*:: MEDLINE formatted String
149
+ def query(*ids)
150
+ host = "www.ncbi.nlm.nih.gov"
151
+ path = "/sites/entrez?tool=bioruby&cmd=Text&dopt=MEDLINE&db=PubMed&uid="
152
+ list = ids.collect { |x| CGI.escape(x.to_s) }.join(",")
153
+
154
+ ncbi_access_wait
155
+
156
+ http = Bio::Command.new_http(host)
157
+ response = http.get(path + list)
158
+ result = response.body
159
+ result = result.scan(/<pre>\s*(.*?)<\/pre>/m).flatten
160
+
161
+ if result =~ /id:.*Error occurred/
162
+ # id: xxxxx Error occurred: Article does not exist
163
+ raise( result )
164
+ else
165
+ if ids.size > 1
166
+ return result
167
+ else
168
+ return result.first
169
+ end
170
+ end
171
+ end
172
+
173
+ # Retrieve PubMed entry by PMID and returns MEDLINE formatted string using
174
+ # entrez pmfetch.
175
+ # ---
176
+ # *Arguments*:
177
+ # * _id_: PubMed ID (required)
178
+ # *Returns*:: MEDLINE formatted String
179
+ def pmfetch(id)
180
+ host = "www.ncbi.nlm.nih.gov"
181
+ path = "/entrez/utils/pmfetch.fcgi?tool=bioruby&mode=text&report=medline&db=PubMed&id="
182
+
183
+ ncbi_access_wait
184
+
185
+ http = Bio::Command.new_http(host)
186
+ response = http.get(path + CGI.escape(id.to_s))
187
+ result = response.body
188
+ if result =~ /#{id}\s+Error/
189
+ raise( result )
190
+ else
191
+ result = result.gsub("\r", "\n").squeeze("\n").gsub(/<\/?pre>/, '')
192
+ return result
193
+ end
194
+ end
195
+
196
+ def self.esearch(*args)
197
+ self.new.esearch(*args)
198
+ end
199
+
200
+ def self.efetch(*args)
201
+ self.new.efetch(*args)
202
+ end
203
+
204
+ def self.search(*args)
205
+ self.new.search(*args)
206
+ end
207
+
208
+ def self.query(*args)
209
+ self.new.query(*args)
210
+ end
211
+
212
+ def self.pmfetch(*args)
213
+ self.new.pmfetch(*args)
214
+ end
215
+
216
+ end # PubMed
217
+
218
+ end # Bio
219
+
220
+
221
+ if __FILE__ == $0
222
+
223
+ puts "=== instance methods ==="
224
+
225
+ pubmed = Bio::PubMed.new
226
+
227
+ puts "--- Search PubMed by E-Utils ---"
228
+ opts = {"rettype" => "count"}
229
+ puts Time.now
230
+ puts pubmed.esearch("(genome AND analysis) OR bioinformatics", opts)
231
+ puts Time.now
232
+ puts pubmed.esearch("(genome AND analysis) OR bioinformatics", opts)
233
+ puts Time.now
234
+ puts pubmed.esearch("(genome AND analysis) OR bioinformatics", opts)
235
+ puts Time.now
236
+ pubmed.esearch("(genome AND analysis) OR bioinformatics").each do |x|
237
+ puts x
238
+ end
239
+
240
+ puts "--- Retrieve PubMed entry by E-Utils ---"
241
+ puts Time.now
242
+ puts pubmed.efetch(16381885)
243
+ puts Time.now
244
+ puts pubmed.efetch("16381885")
245
+ puts Time.now
246
+ puts pubmed.efetch("16381885")
247
+ puts Time.now
248
+ opts = {"retmode" => "xml"}
249
+ puts pubmed.efetch([10592173, 14693808], opts)
250
+ puts Time.now
251
+ puts pubmed.efetch(["10592173", "14693808"], opts)
252
+
253
+ puts "--- Search PubMed by Entrez CGI ---"
254
+ pubmed.search("(genome AND analysis) OR bioinformatics").each do |x|
255
+ p x
256
+ end
257
+
258
+ puts "--- Retrieve PubMed entry by Entrez CGI ---"
259
+ puts pubmed.query("16381885")
260
+
261
+
262
+ puts "--- Retrieve PubMed entry by PMfetch ---"
263
+ puts pubmed.pmfetch("16381885")
264
+
265
+
266
+ puts "=== class methods ==="
267
+
268
+
269
+ puts "--- Search PubMed by E-Utils ---"
270
+ opts = {"rettype" => "count"}
271
+ puts Time.now
272
+ puts Bio::PubMed.esearch("(genome AND analysis) OR bioinformatics", opts)
273
+ puts Time.now
274
+ puts Bio::PubMed.esearch("(genome AND analysis) OR bioinformatics", opts)
275
+ puts Time.now
276
+ puts Bio::PubMed.esearch("(genome AND analysis) OR bioinformatics", opts)
277
+ puts Time.now
278
+ Bio::PubMed.esearch("(genome AND analysis) OR bioinformatics").each do |x|
279
+ puts x
280
+ end
281
+
282
+ puts "--- Retrieve PubMed entry by E-Utils ---"
283
+ puts Time.now
284
+ puts Bio::PubMed.efetch(16381885)
285
+ puts Time.now
286
+ puts Bio::PubMed.efetch("16381885")
287
+ puts Time.now
288
+ puts Bio::PubMed.efetch("16381885")
289
+ puts Time.now
290
+ opts = {"retmode" => "xml"}
291
+ puts Bio::PubMed.efetch([10592173, 14693808], opts)
292
+ puts Time.now
293
+ puts Bio::PubMed.efetch(["10592173", "14693808"], opts)
294
+
295
+ puts "--- Search PubMed by Entrez CGI ---"
296
+ Bio::PubMed.search("(genome AND analysis) OR bioinformatics").each do |x|
297
+ p x
298
+ end
299
+
300
+ puts "--- Retrieve PubMed entry by Entrez CGI ---"
301
+ puts Bio::PubMed.query("16381885")
302
+
303
+
304
+ puts "--- Retrieve PubMed entry by PMfetch ---"
305
+ puts Bio::PubMed.pmfetch("16381885")
306
+
307
+ end