wwood-bioruby 1.2.11

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Files changed (386) hide show
  1. data/README.rdoc +205 -0
  2. data/README_DEV.rdoc +285 -0
  3. data/VERSION.yml +4 -0
  4. data/bin/bioruby +44 -0
  5. data/bin/br_biofetch.rb +47 -0
  6. data/bin/br_bioflat.rb +293 -0
  7. data/bin/br_biogetseq.rb +45 -0
  8. data/bin/br_pmfetch.rb +421 -0
  9. data/lib/bio.rb +306 -0
  10. data/lib/bio/alignment.rb +2518 -0
  11. data/lib/bio/appl/bl2seq/report.rb +334 -0
  12. data/lib/bio/appl/blast.rb +505 -0
  13. data/lib/bio/appl/blast/ddbj.rb +142 -0
  14. data/lib/bio/appl/blast/format0.rb +1438 -0
  15. data/lib/bio/appl/blast/format8.rb +83 -0
  16. data/lib/bio/appl/blast/genomenet.rb +263 -0
  17. data/lib/bio/appl/blast/ncbioptions.rb +220 -0
  18. data/lib/bio/appl/blast/remote.rb +105 -0
  19. data/lib/bio/appl/blast/report.rb +767 -0
  20. data/lib/bio/appl/blast/rexml.rb +144 -0
  21. data/lib/bio/appl/blast/rpsblast.rb +277 -0
  22. data/lib/bio/appl/blast/wublast.rb +635 -0
  23. data/lib/bio/appl/blast/xmlparser.rb +236 -0
  24. data/lib/bio/appl/blat/report.rb +530 -0
  25. data/lib/bio/appl/clustalw.rb +219 -0
  26. data/lib/bio/appl/clustalw/report.rb +152 -0
  27. data/lib/bio/appl/emboss.rb +203 -0
  28. data/lib/bio/appl/fasta.rb +235 -0
  29. data/lib/bio/appl/fasta/format10.rb +325 -0
  30. data/lib/bio/appl/gcg/msf.rb +212 -0
  31. data/lib/bio/appl/gcg/seq.rb +195 -0
  32. data/lib/bio/appl/genscan/report.rb +552 -0
  33. data/lib/bio/appl/hmmer.rb +126 -0
  34. data/lib/bio/appl/hmmer/report.rb +683 -0
  35. data/lib/bio/appl/iprscan/report.rb +374 -0
  36. data/lib/bio/appl/mafft.rb +259 -0
  37. data/lib/bio/appl/mafft/report.rb +226 -0
  38. data/lib/bio/appl/muscle.rb +52 -0
  39. data/lib/bio/appl/paml/baseml.rb +95 -0
  40. data/lib/bio/appl/paml/baseml/report.rb +32 -0
  41. data/lib/bio/appl/paml/codeml.rb +242 -0
  42. data/lib/bio/appl/paml/codeml/rates.rb +67 -0
  43. data/lib/bio/appl/paml/codeml/report.rb +67 -0
  44. data/lib/bio/appl/paml/common.rb +348 -0
  45. data/lib/bio/appl/paml/common_report.rb +38 -0
  46. data/lib/bio/appl/paml/yn00.rb +103 -0
  47. data/lib/bio/appl/paml/yn00/report.rb +32 -0
  48. data/lib/bio/appl/phylip/alignment.rb +133 -0
  49. data/lib/bio/appl/phylip/distance_matrix.rb +96 -0
  50. data/lib/bio/appl/probcons.rb +41 -0
  51. data/lib/bio/appl/psort.rb +548 -0
  52. data/lib/bio/appl/psort/report.rb +542 -0
  53. data/lib/bio/appl/pts1.rb +263 -0
  54. data/lib/bio/appl/sim4.rb +124 -0
  55. data/lib/bio/appl/sim4/report.rb +485 -0
  56. data/lib/bio/appl/sosui/report.rb +151 -0
  57. data/lib/bio/appl/spidey/report.rb +593 -0
  58. data/lib/bio/appl/targetp/report.rb +267 -0
  59. data/lib/bio/appl/tcoffee.rb +55 -0
  60. data/lib/bio/appl/tmhmm/report.rb +231 -0
  61. data/lib/bio/command.rb +593 -0
  62. data/lib/bio/compat/features.rb +157 -0
  63. data/lib/bio/compat/references.rb +128 -0
  64. data/lib/bio/data/aa.rb +353 -0
  65. data/lib/bio/data/codontable.rb +722 -0
  66. data/lib/bio/data/na.rb +223 -0
  67. data/lib/bio/db.rb +329 -0
  68. data/lib/bio/db/aaindex.rb +357 -0
  69. data/lib/bio/db/biosql/biosql_to_biosequence.rb +67 -0
  70. data/lib/bio/db/biosql/sequence.rb +508 -0
  71. data/lib/bio/db/embl/common.rb +352 -0
  72. data/lib/bio/db/embl/embl.rb +500 -0
  73. data/lib/bio/db/embl/embl_to_biosequence.rb +85 -0
  74. data/lib/bio/db/embl/format_embl.rb +190 -0
  75. data/lib/bio/db/embl/sptr.rb +1283 -0
  76. data/lib/bio/db/embl/swissprot.rb +42 -0
  77. data/lib/bio/db/embl/trembl.rb +41 -0
  78. data/lib/bio/db/embl/uniprot.rb +42 -0
  79. data/lib/bio/db/fantom.rb +597 -0
  80. data/lib/bio/db/fasta.rb +410 -0
  81. data/lib/bio/db/fasta/defline.rb +532 -0
  82. data/lib/bio/db/fasta/fasta_to_biosequence.rb +63 -0
  83. data/lib/bio/db/fasta/format_fasta.rb +97 -0
  84. data/lib/bio/db/genbank/common.rb +307 -0
  85. data/lib/bio/db/genbank/ddbj.rb +22 -0
  86. data/lib/bio/db/genbank/format_genbank.rb +187 -0
  87. data/lib/bio/db/genbank/genbank.rb +250 -0
  88. data/lib/bio/db/genbank/genbank_to_biosequence.rb +86 -0
  89. data/lib/bio/db/genbank/genpept.rb +60 -0
  90. data/lib/bio/db/genbank/refseq.rb +18 -0
  91. data/lib/bio/db/gff.rb +1846 -0
  92. data/lib/bio/db/go.rb +481 -0
  93. data/lib/bio/db/kegg/brite.rb +41 -0
  94. data/lib/bio/db/kegg/compound.rb +131 -0
  95. data/lib/bio/db/kegg/drug.rb +98 -0
  96. data/lib/bio/db/kegg/enzyme.rb +148 -0
  97. data/lib/bio/db/kegg/expression.rb +155 -0
  98. data/lib/bio/db/kegg/genes.rb +263 -0
  99. data/lib/bio/db/kegg/genome.rb +241 -0
  100. data/lib/bio/db/kegg/glycan.rb +166 -0
  101. data/lib/bio/db/kegg/keggtab.rb +357 -0
  102. data/lib/bio/db/kegg/kgml.rb +256 -0
  103. data/lib/bio/db/kegg/orthology.rb +136 -0
  104. data/lib/bio/db/kegg/reaction.rb +82 -0
  105. data/lib/bio/db/kegg/taxonomy.rb +331 -0
  106. data/lib/bio/db/lasergene.rb +209 -0
  107. data/lib/bio/db/litdb.rb +107 -0
  108. data/lib/bio/db/medline.rb +326 -0
  109. data/lib/bio/db/nbrf.rb +191 -0
  110. data/lib/bio/db/newick.rb +658 -0
  111. data/lib/bio/db/nexus.rb +1854 -0
  112. data/lib/bio/db/pdb.rb +29 -0
  113. data/lib/bio/db/pdb/atom.rb +77 -0
  114. data/lib/bio/db/pdb/chain.rb +210 -0
  115. data/lib/bio/db/pdb/chemicalcomponent.rb +224 -0
  116. data/lib/bio/db/pdb/model.rb +148 -0
  117. data/lib/bio/db/pdb/pdb.rb +1911 -0
  118. data/lib/bio/db/pdb/residue.rb +176 -0
  119. data/lib/bio/db/pdb/utils.rb +399 -0
  120. data/lib/bio/db/prosite.rb +597 -0
  121. data/lib/bio/db/rebase.rb +456 -0
  122. data/lib/bio/db/soft.rb +404 -0
  123. data/lib/bio/db/transfac.rb +375 -0
  124. data/lib/bio/db/url.rb +42 -0
  125. data/lib/bio/feature.rb +139 -0
  126. data/lib/bio/io/biosql/biodatabase.rb +64 -0
  127. data/lib/bio/io/biosql/bioentry.rb +29 -0
  128. data/lib/bio/io/biosql/bioentry_dbxref.rb +11 -0
  129. data/lib/bio/io/biosql/bioentry_path.rb +12 -0
  130. data/lib/bio/io/biosql/bioentry_qualifier_value.rb +10 -0
  131. data/lib/bio/io/biosql/bioentry_reference.rb +10 -0
  132. data/lib/bio/io/biosql/bioentry_relationship.rb +10 -0
  133. data/lib/bio/io/biosql/biosequence.rb +11 -0
  134. data/lib/bio/io/biosql/comment.rb +7 -0
  135. data/lib/bio/io/biosql/config/database.yml +20 -0
  136. data/lib/bio/io/biosql/dbxref.rb +13 -0
  137. data/lib/bio/io/biosql/dbxref_qualifier_value.rb +12 -0
  138. data/lib/bio/io/biosql/location.rb +32 -0
  139. data/lib/bio/io/biosql/location_qualifier_value.rb +11 -0
  140. data/lib/bio/io/biosql/ontology.rb +10 -0
  141. data/lib/bio/io/biosql/reference.rb +9 -0
  142. data/lib/bio/io/biosql/seqfeature.rb +32 -0
  143. data/lib/bio/io/biosql/seqfeature_dbxref.rb +11 -0
  144. data/lib/bio/io/biosql/seqfeature_path.rb +11 -0
  145. data/lib/bio/io/biosql/seqfeature_qualifier_value.rb +20 -0
  146. data/lib/bio/io/biosql/seqfeature_relationship.rb +11 -0
  147. data/lib/bio/io/biosql/taxon.rb +12 -0
  148. data/lib/bio/io/biosql/taxon_name.rb +9 -0
  149. data/lib/bio/io/biosql/term.rb +27 -0
  150. data/lib/bio/io/biosql/term_dbxref.rb +11 -0
  151. data/lib/bio/io/biosql/term_path.rb +12 -0
  152. data/lib/bio/io/biosql/term_relationship.rb +13 -0
  153. data/lib/bio/io/biosql/term_relationship_term.rb +11 -0
  154. data/lib/bio/io/biosql/term_synonym.rb +10 -0
  155. data/lib/bio/io/das.rb +461 -0
  156. data/lib/bio/io/dbget.rb +194 -0
  157. data/lib/bio/io/ddbjxml.rb +638 -0
  158. data/lib/bio/io/ebisoap.rb +158 -0
  159. data/lib/bio/io/ensembl.rb +229 -0
  160. data/lib/bio/io/fastacmd.rb +163 -0
  161. data/lib/bio/io/fetch.rb +195 -0
  162. data/lib/bio/io/flatfile.rb +482 -0
  163. data/lib/bio/io/flatfile/autodetection.rb +545 -0
  164. data/lib/bio/io/flatfile/bdb.rb +253 -0
  165. data/lib/bio/io/flatfile/buffer.rb +237 -0
  166. data/lib/bio/io/flatfile/index.rb +1381 -0
  167. data/lib/bio/io/flatfile/indexer.rb +805 -0
  168. data/lib/bio/io/flatfile/splitter.rb +297 -0
  169. data/lib/bio/io/higet.rb +73 -0
  170. data/lib/bio/io/hinv.rb +442 -0
  171. data/lib/bio/io/keggapi.rb +805 -0
  172. data/lib/bio/io/ncbirest.rb +733 -0
  173. data/lib/bio/io/ncbisoap.rb +155 -0
  174. data/lib/bio/io/pubmed.rb +307 -0
  175. data/lib/bio/io/registry.rb +292 -0
  176. data/lib/bio/io/soapwsdl.rb +119 -0
  177. data/lib/bio/io/sql.rb +186 -0
  178. data/lib/bio/location.rb +867 -0
  179. data/lib/bio/map.rb +410 -0
  180. data/lib/bio/pathway.rb +960 -0
  181. data/lib/bio/reference.rb +602 -0
  182. data/lib/bio/sequence.rb +456 -0
  183. data/lib/bio/sequence/aa.rb +152 -0
  184. data/lib/bio/sequence/adapter.rb +108 -0
  185. data/lib/bio/sequence/common.rb +310 -0
  186. data/lib/bio/sequence/compat.rb +123 -0
  187. data/lib/bio/sequence/dblink.rb +54 -0
  188. data/lib/bio/sequence/format.rb +358 -0
  189. data/lib/bio/sequence/format_raw.rb +23 -0
  190. data/lib/bio/sequence/generic.rb +24 -0
  191. data/lib/bio/sequence/na.rb +491 -0
  192. data/lib/bio/shell.rb +44 -0
  193. data/lib/bio/shell/core.rb +578 -0
  194. data/lib/bio/shell/demo.rb +146 -0
  195. data/lib/bio/shell/interface.rb +218 -0
  196. data/lib/bio/shell/irb.rb +95 -0
  197. data/lib/bio/shell/object.rb +71 -0
  198. data/lib/bio/shell/plugin/blast.rb +42 -0
  199. data/lib/bio/shell/plugin/codon.rb +218 -0
  200. data/lib/bio/shell/plugin/das.rb +58 -0
  201. data/lib/bio/shell/plugin/emboss.rb +23 -0
  202. data/lib/bio/shell/plugin/entry.rb +105 -0
  203. data/lib/bio/shell/plugin/flatfile.rb +101 -0
  204. data/lib/bio/shell/plugin/keggapi.rb +181 -0
  205. data/lib/bio/shell/plugin/midi.rb +430 -0
  206. data/lib/bio/shell/plugin/obda.rb +45 -0
  207. data/lib/bio/shell/plugin/psort.rb +56 -0
  208. data/lib/bio/shell/plugin/seq.rb +247 -0
  209. data/lib/bio/shell/plugin/soap.rb +87 -0
  210. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/bioruby_generator.rb +29 -0
  211. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/_classes.rhtml +4 -0
  212. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/_log.rhtml +27 -0
  213. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/_methods.rhtml +11 -0
  214. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/_modules.rhtml +4 -0
  215. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/_variables.rhtml +7 -0
  216. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby-bg.gif +0 -0
  217. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby-gem.png +0 -0
  218. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby-link.gif +0 -0
  219. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby.css +368 -0
  220. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby.rhtml +47 -0
  221. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby_controller.rb +144 -0
  222. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/bioruby_helper.rb +47 -0
  223. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/commands.rhtml +8 -0
  224. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/history.rhtml +10 -0
  225. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/index.rhtml +26 -0
  226. data/lib/bio/shell/rails/vendor/plugins/bioruby/generators/bioruby/templates/spinner.gif +0 -0
  227. data/lib/bio/shell/script.rb +25 -0
  228. data/lib/bio/shell/setup.rb +109 -0
  229. data/lib/bio/shell/web.rb +102 -0
  230. data/lib/bio/tree.rb +852 -0
  231. data/lib/bio/util/color_scheme.rb +191 -0
  232. data/lib/bio/util/color_scheme/buried.rb +59 -0
  233. data/lib/bio/util/color_scheme/helix.rb +59 -0
  234. data/lib/bio/util/color_scheme/hydropathy.rb +64 -0
  235. data/lib/bio/util/color_scheme/nucleotide.rb +31 -0
  236. data/lib/bio/util/color_scheme/strand.rb +59 -0
  237. data/lib/bio/util/color_scheme/taylor.rb +50 -0
  238. data/lib/bio/util/color_scheme/turn.rb +59 -0
  239. data/lib/bio/util/color_scheme/zappo.rb +50 -0
  240. data/lib/bio/util/contingency_table.rb +370 -0
  241. data/lib/bio/util/restriction_enzyme.rb +228 -0
  242. data/lib/bio/util/restriction_enzyme/analysis.rb +249 -0
  243. data/lib/bio/util/restriction_enzyme/analysis_basic.rb +217 -0
  244. data/lib/bio/util/restriction_enzyme/cut_symbol.rb +107 -0
  245. data/lib/bio/util/restriction_enzyme/double_stranded.rb +321 -0
  246. data/lib/bio/util/restriction_enzyme/double_stranded/aligned_strands.rb +130 -0
  247. data/lib/bio/util/restriction_enzyme/double_stranded/cut_location_pair.rb +103 -0
  248. data/lib/bio/util/restriction_enzyme/double_stranded/cut_location_pair_in_enzyme_notation.rb +38 -0
  249. data/lib/bio/util/restriction_enzyme/double_stranded/cut_locations.rb +76 -0
  250. data/lib/bio/util/restriction_enzyme/double_stranded/cut_locations_in_enzyme_notation.rb +107 -0
  251. data/lib/bio/util/restriction_enzyme/enzymes.yaml +7061 -0
  252. data/lib/bio/util/restriction_enzyme/range/cut_range.rb +24 -0
  253. data/lib/bio/util/restriction_enzyme/range/cut_ranges.rb +47 -0
  254. data/lib/bio/util/restriction_enzyme/range/horizontal_cut_range.rb +67 -0
  255. data/lib/bio/util/restriction_enzyme/range/sequence_range.rb +257 -0
  256. data/lib/bio/util/restriction_enzyme/range/sequence_range/calculated_cuts.rb +242 -0
  257. data/lib/bio/util/restriction_enzyme/range/sequence_range/fragment.rb +51 -0
  258. data/lib/bio/util/restriction_enzyme/range/sequence_range/fragments.rb +41 -0
  259. data/lib/bio/util/restriction_enzyme/range/vertical_cut_range.rb +77 -0
  260. data/lib/bio/util/restriction_enzyme/single_strand.rb +200 -0
  261. data/lib/bio/util/restriction_enzyme/single_strand/cut_locations_in_enzyme_notation.rb +135 -0
  262. data/lib/bio/util/restriction_enzyme/single_strand_complement.rb +23 -0
  263. data/lib/bio/util/restriction_enzyme/string_formatting.rb +111 -0
  264. data/lib/bio/util/sirna.rb +288 -0
  265. data/test/data/HMMER/hmmpfam.out +64 -0
  266. data/test/data/HMMER/hmmsearch.out +88 -0
  267. data/test/data/SOSUI/sample.report +11 -0
  268. data/test/data/TMHMM/sample.report +21 -0
  269. data/test/data/aaindex/DAYM780301 +30 -0
  270. data/test/data/aaindex/PRAM900102 +20 -0
  271. data/test/data/bl2seq/cd8a_cd8b_blastp.bl2seq +53 -0
  272. data/test/data/bl2seq/cd8a_p53_e-5blastp.bl2seq +37 -0
  273. data/test/data/blast/2.2.15.blastp.m7 +876 -0
  274. data/test/data/blast/b0002.faa +15 -0
  275. data/test/data/blast/b0002.faa.m0 +128 -0
  276. data/test/data/blast/b0002.faa.m7 +65 -0
  277. data/test/data/blast/b0002.faa.m8 +1 -0
  278. data/test/data/blast/blastp-multi.m7 +188 -0
  279. data/test/data/command/echoarg2.bat +1 -0
  280. data/test/data/embl/AB090716.embl +65 -0
  281. data/test/data/embl/AB090716.embl.rel89 +63 -0
  282. data/test/data/fasta/example1.txt +75 -0
  283. data/test/data/fasta/example2.txt +21 -0
  284. data/test/data/genscan/sample.report +63 -0
  285. data/test/data/iprscan/merged.raw +32 -0
  286. data/test/data/iprscan/merged.txt +74 -0
  287. data/test/data/paml/codeml/control_file.txt +30 -0
  288. data/test/data/paml/codeml/output.txt +78 -0
  289. data/test/data/paml/codeml/rates +217 -0
  290. data/test/data/prosite/prosite.dat +2233 -0
  291. data/test/data/refseq/nm_126355.entret +64 -0
  292. data/test/data/rpsblast/misc.rpsblast +193 -0
  293. data/test/data/soft/GDS100_partial.soft +92 -0
  294. data/test/data/soft/GSE3457_family_partial.soft +874 -0
  295. data/test/data/uniprot/p53_human.uniprot +1456 -0
  296. data/test/functional/bio/appl/test_pts1.rb +115 -0
  297. data/test/functional/bio/io/test_ensembl.rb +229 -0
  298. data/test/functional/bio/io/test_soapwsdl.rb +52 -0
  299. data/test/functional/bio/sequence/test_output_embl.rb +51 -0
  300. data/test/functional/bio/test_command.rb +301 -0
  301. data/test/runner.rb +14 -0
  302. data/test/unit/bio/appl/bl2seq/test_report.rb +134 -0
  303. data/test/unit/bio/appl/blast/test_ncbioptions.rb +112 -0
  304. data/test/unit/bio/appl/blast/test_report.rb +1135 -0
  305. data/test/unit/bio/appl/blast/test_rpsblast.rb +398 -0
  306. data/test/unit/bio/appl/genscan/test_report.rb +182 -0
  307. data/test/unit/bio/appl/hmmer/test_report.rb +342 -0
  308. data/test/unit/bio/appl/iprscan/test_report.rb +338 -0
  309. data/test/unit/bio/appl/mafft/test_report.rb +63 -0
  310. data/test/unit/bio/appl/paml/codeml/test_rates.rb +45 -0
  311. data/test/unit/bio/appl/paml/codeml/test_report.rb +45 -0
  312. data/test/unit/bio/appl/paml/test_codeml.rb +174 -0
  313. data/test/unit/bio/appl/sosui/test_report.rb +81 -0
  314. data/test/unit/bio/appl/targetp/test_report.rb +146 -0
  315. data/test/unit/bio/appl/test_blast.rb +277 -0
  316. data/test/unit/bio/appl/test_fasta.rb +130 -0
  317. data/test/unit/bio/appl/test_psort.rb +57 -0
  318. data/test/unit/bio/appl/test_pts1.rb +77 -0
  319. data/test/unit/bio/appl/tmhmm/test_report.rb +126 -0
  320. data/test/unit/bio/data/test_aa.rb +90 -0
  321. data/test/unit/bio/data/test_codontable.rb +107 -0
  322. data/test/unit/bio/data/test_na.rb +80 -0
  323. data/test/unit/bio/db/embl/test_common.rb +117 -0
  324. data/test/unit/bio/db/embl/test_embl.rb +214 -0
  325. data/test/unit/bio/db/embl/test_embl_rel89.rb +219 -0
  326. data/test/unit/bio/db/embl/test_embl_to_bioseq.rb +203 -0
  327. data/test/unit/bio/db/embl/test_sptr.rb +1812 -0
  328. data/test/unit/bio/db/embl/test_uniprot.rb +31 -0
  329. data/test/unit/bio/db/kegg/test_genes.rb +45 -0
  330. data/test/unit/bio/db/pdb/test_pdb.rb +152 -0
  331. data/test/unit/bio/db/test_aaindex.rb +197 -0
  332. data/test/unit/bio/db/test_fasta.rb +250 -0
  333. data/test/unit/bio/db/test_gff.rb +1190 -0
  334. data/test/unit/bio/db/test_lasergene.rb +95 -0
  335. data/test/unit/bio/db/test_medline.rb +127 -0
  336. data/test/unit/bio/db/test_newick.rb +293 -0
  337. data/test/unit/bio/db/test_nexus.rb +364 -0
  338. data/test/unit/bio/db/test_prosite.rb +1437 -0
  339. data/test/unit/bio/db/test_rebase.rb +101 -0
  340. data/test/unit/bio/db/test_soft.rb +138 -0
  341. data/test/unit/bio/db/test_url.rb +36 -0
  342. data/test/unit/bio/io/flatfile/test_autodetection.rb +375 -0
  343. data/test/unit/bio/io/flatfile/test_buffer.rb +251 -0
  344. data/test/unit/bio/io/flatfile/test_splitter.rb +369 -0
  345. data/test/unit/bio/io/test_ddbjxml.rb +80 -0
  346. data/test/unit/bio/io/test_ensembl.rb +109 -0
  347. data/test/unit/bio/io/test_fastacmd.rb +42 -0
  348. data/test/unit/bio/io/test_flatfile.rb +505 -0
  349. data/test/unit/bio/io/test_soapwsdl.rb +32 -0
  350. data/test/unit/bio/sequence/test_aa.rb +115 -0
  351. data/test/unit/bio/sequence/test_common.rb +373 -0
  352. data/test/unit/bio/sequence/test_compat.rb +69 -0
  353. data/test/unit/bio/sequence/test_dblink.rb +58 -0
  354. data/test/unit/bio/sequence/test_na.rb +330 -0
  355. data/test/unit/bio/shell/plugin/test_seq.rb +185 -0
  356. data/test/unit/bio/test_alignment.rb +1025 -0
  357. data/test/unit/bio/test_command.rb +349 -0
  358. data/test/unit/bio/test_db.rb +96 -0
  359. data/test/unit/bio/test_feature.rb +144 -0
  360. data/test/unit/bio/test_location.rb +599 -0
  361. data/test/unit/bio/test_map.rb +230 -0
  362. data/test/unit/bio/test_pathway.rb +499 -0
  363. data/test/unit/bio/test_reference.rb +252 -0
  364. data/test/unit/bio/test_sequence.rb +329 -0
  365. data/test/unit/bio/test_shell.rb +18 -0
  366. data/test/unit/bio/test_tree.rb +593 -0
  367. data/test/unit/bio/util/restriction_enzyme/analysis/test_calculated_cuts.rb +299 -0
  368. data/test/unit/bio/util/restriction_enzyme/analysis/test_cut_ranges.rb +103 -0
  369. data/test/unit/bio/util/restriction_enzyme/analysis/test_sequence_range.rb +240 -0
  370. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_aligned_strands.rb +101 -0
  371. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_location_pair.rb +75 -0
  372. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_location_pair_in_enzyme_notation.rb +73 -0
  373. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_locations.rb +53 -0
  374. data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_locations_in_enzyme_notation.rb +104 -0
  375. data/test/unit/bio/util/restriction_enzyme/single_strand/test_cut_locations_in_enzyme_notation.rb +83 -0
  376. data/test/unit/bio/util/restriction_enzyme/test_analysis.rb +246 -0
  377. data/test/unit/bio/util/restriction_enzyme/test_cut_symbol.rb +44 -0
  378. data/test/unit/bio/util/restriction_enzyme/test_double_stranded.rb +115 -0
  379. data/test/unit/bio/util/restriction_enzyme/test_single_strand.rb +147 -0
  380. data/test/unit/bio/util/restriction_enzyme/test_single_strand_complement.rb +147 -0
  381. data/test/unit/bio/util/restriction_enzyme/test_string_formatting.rb +60 -0
  382. data/test/unit/bio/util/test_color_scheme.rb +33 -0
  383. data/test/unit/bio/util/test_contingency_table.rb +94 -0
  384. data/test/unit/bio/util/test_restriction_enzyme.rb +42 -0
  385. data/test/unit/bio/util/test_sirna.rb +245 -0
  386. metadata +543 -0
@@ -0,0 +1,158 @@
1
+ #
2
+ # = bio/io/emblsoap.rb - EBI SOAP server access class
3
+ #
4
+ # Copyright:: Copyright (C) 2006
5
+ # Toshiaki Katayama <k@bioruby.org>
6
+ # License:: The Ruby License
7
+ #
8
+ # $Id: ebisoap.rb,v 1.3 2007/04/05 23:35:41 trevor Exp $
9
+ #
10
+
11
+ require 'bio/io/soapwsdl'
12
+
13
+ module Bio
14
+ class EBI
15
+
16
+ class SOAP < Bio::SOAPWSDL
17
+
18
+ BASE_URI = "http://www.ebi.ac.uk/Tools/webservices/wsdl/"
19
+
20
+ # set default to Dbfetch
21
+ SERVER_URI = BASE_URI + "WSDbfetch.wsdl"
22
+
23
+ def initialize(wsdl = nil)
24
+ super(wsdl || self.class::SERVER_URI)
25
+ end
26
+
27
+ # * fetchData
28
+ # * getSupportedDBs
29
+ # * getSupportedFormats
30
+ # * getSupportedStyles
31
+ class Dbfetch < Bio::EBI::SOAP
32
+ SERVER_URI = BASE_URI + "WSDbfetch.wsdl"
33
+ end
34
+
35
+ # * checkStatus
36
+ # * doIprscan
37
+ # * getResults
38
+ # * poll
39
+ # * polljob
40
+ # * runInterProScan
41
+ # * test
42
+ class InterProScan < Bio::EBI::SOAP
43
+ SERVER_URI = BASE_URI + "WSInterProScan.wsdl"
44
+ end
45
+
46
+ # * checkStatus
47
+ # * getInfo
48
+ # * getResults
49
+ # * getTools
50
+ # * poll
51
+ # * run
52
+ # * test
53
+ class Emboss < Bio::EBI::SOAP
54
+ SERVER_URI = BASE_URI + "WSEmboss.wsdl"
55
+ end
56
+
57
+ # * checkStatus
58
+ # * getResults
59
+ # * poll
60
+ # * runClustalW
61
+ # * test
62
+ class ClustalW < Bio::EBI::SOAP
63
+ SERVER_URI = BASE_URI + "WSClustalW.wsdl"
64
+ end
65
+
66
+ # * checkStatus
67
+ # * getResults
68
+ # * poll
69
+ # * runTCoffee
70
+ class TCoffee < Bio::EBI::SOAP
71
+ SERVER_URI = BASE_URI + "WSTCoffee.wsdl"
72
+ end
73
+
74
+ # * checkStatus
75
+ # * getResults
76
+ # * poll
77
+ # * runMuscle
78
+ # * test
79
+ class Muscle < Bio::EBI::SOAP
80
+ SERVER_URI = BASE_URI + "WSMuscle.wsdl"
81
+ end
82
+
83
+ # * checkStatus
84
+ # * doFasta
85
+ # * getResults
86
+ # * poll
87
+ # * polljob
88
+ # * runFasta
89
+ class Fasta < Bio::EBI::SOAP
90
+ SERVER_URI = BASE_URI + "WSFasta.wsdl"
91
+ end
92
+
93
+ # * checkStatus
94
+ # * doWUBlast
95
+ # * getIds
96
+ # * getResults
97
+ # * poll
98
+ # * polljob
99
+ # * runWUBlast
100
+ # * test
101
+ class WUBlast < Bio::EBI::SOAP
102
+ SERVER_URI = BASE_URI + "WSWUBlast.wsdl"
103
+ end
104
+
105
+ # * checkStatus
106
+ # * getResults
107
+ # * poll
108
+ # * runMPsrch
109
+ # * test
110
+ class MPsrch < Bio::EBI::SOAP
111
+ SERVER_URI = BASE_URI + "WSMPsrch.wsdl"
112
+ end
113
+
114
+ # * checkStatus
115
+ # * getResults
116
+ # * poll
117
+ # * runScanPS
118
+ # * test
119
+ class ScanPS < Bio::EBI::SOAP
120
+ SERVER_URI = BASE_URI + "WSScanPS.wsdl"
121
+ end
122
+
123
+ class MSD < Bio::EBI::SOAP
124
+ SERVER_URI = "http://www.ebi.ac.uk/msd-srv/docs/api/msd_soap_service.wsdl"
125
+ end
126
+
127
+ class Ontology < Bio::EBI::SOAP
128
+ SERVER_URI = "http://www.ebi.ac.uk/ontology-lookup/OntologyQuery.wsdl"
129
+ end
130
+
131
+ class Citation < Bio::EBI::SOAP
132
+ SERVER_URI = "http://www.ebi.ac.uk/citations/webservices/wsdl"
133
+ end
134
+
135
+ end # SOAP
136
+
137
+ end # EBI
138
+ end # Bio
139
+
140
+
141
+
142
+ if __FILE__ == $0
143
+ serv = Bio::EBI::SOAP::Dbfetch.new
144
+ p serv.getSupportedDBs
145
+
146
+ require 'base64'
147
+
148
+ serv = Bio::EBI::SOAP::Emboss.new
149
+ hash = {"tool" => "water",
150
+ "asequence" => "uniprot:alk1_human",
151
+ "bsequence" => "uniprot:alk1_mouse",
152
+ "email" => "ebisoap@example.org"}
153
+ poll = serv.run(hash, [])
154
+ puts poll
155
+ base = serv.poll(poll, "tooloutput")
156
+ puts Base64.decode64(base)
157
+ end
158
+
@@ -0,0 +1,229 @@
1
+ #
2
+ # = bio/io/ensembl.rb - An Ensembl Genome Browser client.
3
+ #
4
+ # Copyright:: Copyright (C) 2006
5
+ # Mitsuteru C. Nakao <n@bioruby.org>
6
+ # License:: The Ruby License
7
+ #
8
+ # $Id:$
9
+ #
10
+ # == Description
11
+ #
12
+ # Client classes for Ensembl Genome Browser.
13
+ #
14
+ # == Examples
15
+ #
16
+ # human = Bio::Ensembl.new('Homo_sapiens')
17
+ # seq = human.exportview(1, 1000, 100000)
18
+ # gff = human.exportview(1, 1000, 100000, ['gene', 'variation', 'genscan'])
19
+ #
20
+ # human = Bio::Ensembl.human
21
+ # seq = human.exportview(1, 1000, 100000)
22
+ # gff = human.exportview(1, 1000, 100000, ['gene'])
23
+ #
24
+ # seq = Bio::Ensembl.human.exportview(1, 1000, 100000)
25
+ # gff = Bio::Ensembl.human.exportview(1, 1000, 100000, ['gene', 'variation', 'genscan'])
26
+ #
27
+ #
28
+ # == References
29
+ #
30
+ # * Ensembl
31
+ # http:/www.ensembl.org/
32
+ #
33
+
34
+ require 'bio/command'
35
+
36
+ module Bio
37
+
38
+ # == Description
39
+ #
40
+ # An Ensembl Genome Browser client class.
41
+ #
42
+ # == Examples
43
+ #
44
+ # human = Bio::Ensembl.new('Homo_sapiens')
45
+ # seq = human.exportview(1, 1000, 100000)
46
+ # gff = human.exportview(1, 1000, 100000, ['gene'])
47
+ #
48
+ # mouse = Bio::Ensembl.new('Mus_musculus')
49
+ # seq = mouse.exportview(1, 1000, 100000)
50
+ # gff = mouse.exportview(1, 1000, 100000, ['gene', 'variation', 'genscan'])
51
+ #
52
+ # rice = Bio::Enesmbl.new('Oryza_sativa', 'http://www.gramene.org')
53
+ # seq = rice.exportview(1, 1000, 100000)
54
+ #
55
+ # == References
56
+ #
57
+ # * Ensembl
58
+ # http:/www.ensembl.org/
59
+ #
60
+ # * GRAMENE
61
+ # http://www.gramene.org/
62
+ #
63
+ class Ensembl
64
+
65
+ ENSEMBL_URL = 'http://www.ensembl.org'
66
+
67
+ # Server URL (ex. 'http://www.ensembl.org')
68
+ attr_reader :server
69
+
70
+ # Organism name. (ex. 'Homo_sapiens').
71
+ attr_reader :organism
72
+
73
+ def initialize(organism, server = nil)
74
+ @server = server || ENSEMBL_URL
75
+ @organism = organism
76
+ @uri = [ @server.chomp('/'), @organism ].join('/')
77
+ end
78
+
79
+ def self.human
80
+ self.new("Homo_sapiens")
81
+ end
82
+
83
+ def self.mouse
84
+ self.new("Mus_musculus")
85
+ end
86
+
87
+ # Ensembl ExportView Client.
88
+ #
89
+ # Retrieve genomic sequence/features from Ensembl ExportView in plain text.
90
+ # Ensembl ExportView exports genomic data (sequence and features) in
91
+ # several file formats including fasta, GFF and tab.
92
+ #
93
+ # * ExportViwe (http://www.ensembl.org/Homo_sapiens/exportview).
94
+ #
95
+ # == Examples
96
+ #
97
+ # human = Bio::Ensembl.new('Homo_sapiens')
98
+ # or
99
+ # human = Bio::Ensembl.human
100
+ #
101
+ # # Genomic sequence in Fasta format
102
+ # human.exportview(:seq_region_name => 1,
103
+ # :anchor1 => 1149206, :anchor2 => 1149229)
104
+ # human.exportview(1, 1149206, 1149229)
105
+ #
106
+ # # Feature in GFF
107
+ # human.exportview(:seq_region_name => 1,
108
+ # :anchor1 => 1149206, :anchor2 => 1150000,
109
+ # :options => ['similarity', 'repeat',
110
+ # 'genscan', 'variation', 'gene'])
111
+ # human.exportview(1, 1149206, 1150000, ['variation', 'gene'])
112
+ #
113
+ # Feature in TAB
114
+ # human.exportview(:seq_region_name => 1,
115
+ # :anchor1 => 1149206, :anchor2 => 1150000,
116
+ # :options => ['similarity', 'repeat',
117
+ # 'genscan', 'variation', 'gene'],
118
+ # :format => 'tab')
119
+ #
120
+ # == Arguments
121
+ #
122
+ # Bio::Ensembl#exportview method allow both orderd arguments and
123
+ # named arguments. (Note: mandatory arguments are marked by '*').
124
+ #
125
+ # === Orderd Arguments
126
+ #
127
+ # 1. seq_region_name - Chromosome number (*)
128
+ # 2. anchor1 - From coordination (*)
129
+ # 3. anchor2 - To coordination (*)
130
+ # 4. options - Features to export (in :format => 'gff' or 'tab')
131
+ # ['similarity', 'repeat', 'genscan', 'variation',
132
+ # 'gene']
133
+ #
134
+ # === Named Arguments
135
+ #
136
+ # * :seq_region_name - Chromosome number (*)
137
+ # * :anchor1 - From coordination (*)
138
+ # * :anchor2 - To coordination (*)
139
+ # * :type1 - From coordination type ['bp', ]
140
+ # * :type2 - To coordination type ['bp', ]
141
+ # * :upstream - Bp upstream
142
+ # * :downstream - Bp downstream
143
+ # * :format - File format ['fasta', 'gff', 'tab']
144
+ # * :options - Features to export (for :format => 'gff' or 'tab')
145
+ # ['similarity', 'repeat', 'genscan', 'variation',
146
+ # 'gene']
147
+ #
148
+ def exportview(*args)
149
+ defaults = {
150
+ :type1 => 'bp',
151
+ :type2 => 'bp',
152
+ :downstream => '',
153
+ :upstream => '',
154
+ :format => 'fasta',
155
+ :options => [],
156
+ :action => 'export',
157
+ :_format => 'Text',
158
+ :output => 'txt',
159
+ :submit => 'Continue >>'
160
+ }
161
+
162
+ if args.first.class == Hash
163
+ options = args.first
164
+ if options[:options] and options[:format] != 'fasta' and options[:format] != 'tab'
165
+ options.update({:format => 'gff'})
166
+ end
167
+ else
168
+ options = {
169
+ :seq_region_name => args[0],
170
+ :anchor1 => args[1],
171
+ :anchor2 => args[2],
172
+ }
173
+
174
+ case args[3]
175
+ when Array
176
+ options.update({:format => 'gff', :options => args[3]})
177
+ when Hash
178
+ options.update(args[3])
179
+ end
180
+
181
+ if args[4].class == Hash
182
+ options.update(args[4])
183
+ end
184
+ end
185
+
186
+ params = defaults.update(options)
187
+
188
+ result = Bio::Command.post_form("#{@uri}/exportview", params)
189
+
190
+ return result.body
191
+ end
192
+
193
+ end # class Ensembl
194
+
195
+ end # module Bio
196
+
197
+
198
+
199
+ # Codes for backward-compatibility.
200
+ #
201
+ class Bio::Ensembl
202
+ EBIServerURI = ENSEMBL_URL
203
+
204
+ def self.server_uri(uri = nil)
205
+ if uri
206
+ @uri = uri
207
+ else
208
+ @uri || EBIServerURI
209
+ end
210
+ end
211
+
212
+ class Base
213
+ def self.exportview(*args)
214
+ Bio::Ensembl.new(Organism).exportview(*args)
215
+ end
216
+ end
217
+
218
+ class Human < Base
219
+ Organism = Bio::Ensembl.human.organism
220
+ end
221
+
222
+ class Mouse < Base
223
+ Organism = Bio::Ensembl.mouse.organism
224
+ end
225
+ end # class Bio::Ensembl
226
+
227
+
228
+
229
+
@@ -0,0 +1,163 @@
1
+ #
2
+ # = bio/io/fastacmd.rb - NCBI fastacmd wrapper class
3
+ #
4
+ # Copyright:: Copyright (C) 2005, 2006
5
+ # Shuji SHIGENOBU <shige@nibb.ac.jp>,
6
+ # Toshiaki Katayama <k@bioruby.org>,
7
+ # Mitsuteru C. Nakao <n@bioruby.org>,
8
+ # Jan Aerts <jan.aerts@bbsrc.ac.uk>
9
+ # License:: The Ruby License
10
+ #
11
+ # $Id: fastacmd.rb,v 1.16 2007/04/05 23:35:41 trevor Exp $
12
+ #
13
+
14
+ require 'bio/db/fasta'
15
+ require 'bio/io/flatfile'
16
+ require 'bio/command'
17
+
18
+ module Bio
19
+ class Blast
20
+
21
+ # = DESCRIPTION
22
+ #
23
+ # Retrieves FASTA formatted sequences from a blast database using
24
+ # NCBI fastacmd command.
25
+ #
26
+ # This class requires 'fastacmd' command and a blast database
27
+ # (formatted using the '-o' option of 'formatdb').
28
+ #
29
+ # = USAGE
30
+ # require 'bio'
31
+ #
32
+ # fastacmd = Bio::Blast::Fastacmd.new("/db/myblastdb")
33
+ #
34
+ # entry = fastacmd.get_by_id("sp:128U_DROME")
35
+ # fastacmd.fetch("sp:128U_DROME")
36
+ # fastacmd.fetch(["sp:1433_SPIOL", "sp:1432_MAIZE"])
37
+ #
38
+ # fastacmd.fetch(["sp:1433_SPIOL", "sp:1432_MAIZE"]).each do |fasta|
39
+ # puts fasta
40
+ # end
41
+ #
42
+ # = REFERENCES
43
+ #
44
+ # * NCBI tool
45
+ # ftp://ftp.ncbi.nih.gov/blast/executables/LATEST/ncbi.tar.gz
46
+ #
47
+ # * fastacmd.html
48
+ # http://biowulf.nih.gov/apps/blast/doc/fastacmd.html
49
+ #
50
+ class Fastacmd
51
+
52
+ include Enumerable
53
+
54
+ # Database file path.
55
+ attr_accessor :database
56
+
57
+ # fastacmd command file path.
58
+ attr_accessor :fastacmd
59
+
60
+ # This method provides a handle to a BLASTable database, which you can then
61
+ # use to retrieve sequences.
62
+ #
63
+ # Prerequisites:
64
+ # * You have created a BLASTable database with the '-o T' option.
65
+ # * You have the NCBI fastacmd tool installed.
66
+ #
67
+ # For example, suppose the original input file looks like:
68
+ # >my_seq_1
69
+ # ACCGACCTCCGGAACGGATAGCCCGACCTACG
70
+ # >my_seq_2
71
+ # TCCGACCTTTCCTACCGCACACCTACGCCATCAC
72
+ # ...
73
+ # and you've created a BLASTable database from that with the command
74
+ # cd /my_dir/
75
+ # formatdb -i my_input_file -t Test -n Test -o T
76
+ # then you can get a handle to this database with the command
77
+ # fastacmd = Bio::Blast::Fastacmd.new("/my_dir/Test")
78
+ # ---
79
+ # *Arguments*:
80
+ # * _database_:: path and name of BLASTable database
81
+ def initialize(blast_database_file_path)
82
+ @database = blast_database_file_path
83
+ @fastacmd = 'fastacmd'
84
+ end
85
+
86
+
87
+ # Get the sequence of a specific entry in the BLASTable database.
88
+ # For example:
89
+ # entry = fastacmd.get_by_id("sp:128U_DROME")
90
+ # ---
91
+ # *Arguments*:
92
+ # * _id_: id of an entry in the BLAST database
93
+ # *Returns*:: a Bio::FastaFormat object
94
+ def get_by_id(entry_id)
95
+ fetch(entry_id).shift
96
+ end
97
+
98
+ # Get the sequence for a _list_ of IDs in the database.
99
+ #
100
+ # For example:
101
+ # p fastacmd.fetch(["sp:1433_SPIOL", "sp:1432_MAIZE"])
102
+ #
103
+ # This method always returns an array of Bio::FastaFormat objects, even when
104
+ # the result is a single entry.
105
+ # ---
106
+ # *Arguments*:
107
+ # * _ids_: list of IDs to retrieve from the database
108
+ # *Returns*:: array of Bio::FastaFormat objects
109
+ def fetch(list)
110
+ if list.respond_to?(:join)
111
+ entry_id = list.join(",")
112
+ else
113
+ entry_id = list
114
+ end
115
+
116
+ cmd = [ @fastacmd, '-d', @database, '-s', entry_id ]
117
+ Bio::Command.call_command(cmd) do |io|
118
+ io.close_write
119
+ Bio::FlatFile.new(Bio::FastaFormat, io).to_a
120
+ end
121
+ end
122
+
123
+ # Iterates over _all_ sequences in the database.
124
+ #
125
+ # fastacmd.each_entry do |fasta|
126
+ # p [ fasta.definition[0..30], fasta.seq.size ]
127
+ # end
128
+ # ---
129
+ # *Returns*:: a Bio::FastaFormat object for each iteration
130
+ def each_entry
131
+ cmd = [ @fastacmd, '-d', @database, '-D', '1' ]
132
+ Bio::Command.call_command(cmd) do |io|
133
+ io.close_write
134
+ Bio::FlatFile.open(Bio::FastaFormat, io) do |f|
135
+ f.each_entry do |entry|
136
+ yield entry
137
+ end
138
+ end
139
+ end
140
+ self
141
+ end
142
+ alias each each_entry
143
+
144
+ end # class Fastacmd
145
+
146
+ end # class Blast
147
+ end # module Bio
148
+
149
+ if $0 == __FILE__
150
+ fastacmd = Bio::Blast::Fastacmd.new("/path_to_my_db/db_name")
151
+ seq = fastacmd.get_by_id('id_of_entry1')
152
+ puts seq.class
153
+ puts seq
154
+
155
+ seqs = fastacmd.fetch(['id_of_entry1','id_of_entry2'])
156
+ seqs.each do |seq|
157
+ puts seq
158
+ end
159
+
160
+ fastacmd.each_entry do |fasta|
161
+ puts fasta.seq.size.to_s + "\t" + fasta.definition
162
+ end
163
+ end