@synsci/cli-darwin-x64-baseline 1.1.77 → 1.1.78

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (830) hide show
  1. package/bin/skills/adaptyv/SKILL.md +114 -0
  2. package/bin/skills/adaptyv/reference/api_reference.md +308 -0
  3. package/bin/skills/adaptyv/reference/examples.md +913 -0
  4. package/bin/skills/adaptyv/reference/experiments.md +360 -0
  5. package/bin/skills/adaptyv/reference/protein_optimization.md +637 -0
  6. package/bin/skills/aeon/SKILL.md +374 -0
  7. package/bin/skills/aeon/references/anomaly_detection.md +154 -0
  8. package/bin/skills/aeon/references/classification.md +144 -0
  9. package/bin/skills/aeon/references/clustering.md +123 -0
  10. package/bin/skills/aeon/references/datasets_benchmarking.md +387 -0
  11. package/bin/skills/aeon/references/distances.md +256 -0
  12. package/bin/skills/aeon/references/forecasting.md +140 -0
  13. package/bin/skills/aeon/references/networks.md +289 -0
  14. package/bin/skills/aeon/references/regression.md +118 -0
  15. package/bin/skills/aeon/references/segmentation.md +163 -0
  16. package/bin/skills/aeon/references/similarity_search.md +187 -0
  17. package/bin/skills/aeon/references/transformations.md +246 -0
  18. package/bin/skills/alphafold-database/SKILL.md +513 -0
  19. package/bin/skills/alphafold-database/references/api_reference.md +423 -0
  20. package/bin/skills/anndata/SKILL.md +400 -0
  21. package/bin/skills/anndata/references/best_practices.md +525 -0
  22. package/bin/skills/anndata/references/concatenation.md +396 -0
  23. package/bin/skills/anndata/references/data_structure.md +314 -0
  24. package/bin/skills/anndata/references/io_operations.md +404 -0
  25. package/bin/skills/anndata/references/manipulation.md +516 -0
  26. package/bin/skills/arboreto/SKILL.md +243 -0
  27. package/bin/skills/arboreto/references/algorithms.md +138 -0
  28. package/bin/skills/arboreto/references/basic_inference.md +151 -0
  29. package/bin/skills/arboreto/references/distributed_computing.md +242 -0
  30. package/bin/skills/arboreto/scripts/basic_grn_inference.py +97 -0
  31. package/bin/skills/astropy/SKILL.md +331 -0
  32. package/bin/skills/astropy/references/coordinates.md +273 -0
  33. package/bin/skills/astropy/references/cosmology.md +307 -0
  34. package/bin/skills/astropy/references/fits.md +396 -0
  35. package/bin/skills/astropy/references/tables.md +489 -0
  36. package/bin/skills/astropy/references/time.md +404 -0
  37. package/bin/skills/astropy/references/units.md +178 -0
  38. package/bin/skills/astropy/references/wcs_and_other_modules.md +373 -0
  39. package/bin/skills/benchling-integration/SKILL.md +480 -0
  40. package/bin/skills/benchling-integration/references/api_endpoints.md +883 -0
  41. package/bin/skills/benchling-integration/references/authentication.md +379 -0
  42. package/bin/skills/benchling-integration/references/sdk_reference.md +774 -0
  43. package/bin/skills/biopython/SKILL.md +443 -0
  44. package/bin/skills/biopython/references/advanced.md +577 -0
  45. package/bin/skills/biopython/references/alignment.md +362 -0
  46. package/bin/skills/biopython/references/blast.md +455 -0
  47. package/bin/skills/biopython/references/databases.md +484 -0
  48. package/bin/skills/biopython/references/phylogenetics.md +566 -0
  49. package/bin/skills/biopython/references/sequence_io.md +285 -0
  50. package/bin/skills/biopython/references/structure.md +564 -0
  51. package/bin/skills/biorxiv-database/SKILL.md +483 -0
  52. package/bin/skills/biorxiv-database/references/api_reference.md +280 -0
  53. package/bin/skills/biorxiv-database/scripts/biorxiv_search.py +445 -0
  54. package/bin/skills/bioservices/SKILL.md +361 -0
  55. package/bin/skills/bioservices/references/identifier_mapping.md +685 -0
  56. package/bin/skills/bioservices/references/services_reference.md +636 -0
  57. package/bin/skills/bioservices/references/workflow_patterns.md +811 -0
  58. package/bin/skills/bioservices/scripts/batch_id_converter.py +347 -0
  59. package/bin/skills/bioservices/scripts/compound_cross_reference.py +378 -0
  60. package/bin/skills/bioservices/scripts/pathway_analysis.py +309 -0
  61. package/bin/skills/bioservices/scripts/protein_analysis_workflow.py +408 -0
  62. package/bin/skills/brenda-database/SKILL.md +719 -0
  63. package/bin/skills/brenda-database/references/api_reference.md +537 -0
  64. package/bin/skills/brenda-database/scripts/brenda_queries.py +844 -0
  65. package/bin/skills/brenda-database/scripts/brenda_visualization.py +772 -0
  66. package/bin/skills/brenda-database/scripts/enzyme_pathway_builder.py +1053 -0
  67. package/bin/skills/cellxgene-census/SKILL.md +511 -0
  68. package/bin/skills/cellxgene-census/references/census_schema.md +182 -0
  69. package/bin/skills/cellxgene-census/references/common_patterns.md +351 -0
  70. package/bin/skills/chembl-database/SKILL.md +389 -0
  71. package/bin/skills/chembl-database/references/api_reference.md +272 -0
  72. package/bin/skills/chembl-database/scripts/example_queries.py +278 -0
  73. package/bin/skills/cirq/SKILL.md +346 -0
  74. package/bin/skills/cirq/references/building.md +307 -0
  75. package/bin/skills/cirq/references/experiments.md +572 -0
  76. package/bin/skills/cirq/references/hardware.md +515 -0
  77. package/bin/skills/cirq/references/noise.md +515 -0
  78. package/bin/skills/cirq/references/simulation.md +350 -0
  79. package/bin/skills/cirq/references/transformation.md +416 -0
  80. package/bin/skills/clinicaltrials-database/SKILL.md +507 -0
  81. package/bin/skills/clinicaltrials-database/references/api_reference.md +358 -0
  82. package/bin/skills/clinicaltrials-database/scripts/query_clinicaltrials.py +215 -0
  83. package/bin/skills/clinpgx-database/SKILL.md +638 -0
  84. package/bin/skills/clinpgx-database/references/api_reference.md +757 -0
  85. package/bin/skills/clinpgx-database/scripts/query_clinpgx.py +518 -0
  86. package/bin/skills/clinvar-database/SKILL.md +362 -0
  87. package/bin/skills/clinvar-database/references/api_reference.md +227 -0
  88. package/bin/skills/clinvar-database/references/clinical_significance.md +218 -0
  89. package/bin/skills/clinvar-database/references/data_formats.md +358 -0
  90. package/bin/skills/cobrapy/SKILL.md +463 -0
  91. package/bin/skills/cobrapy/references/api_quick_reference.md +655 -0
  92. package/bin/skills/cobrapy/references/workflows.md +593 -0
  93. package/bin/skills/cosmic-database/SKILL.md +336 -0
  94. package/bin/skills/cosmic-database/references/cosmic_data_reference.md +220 -0
  95. package/bin/skills/cosmic-database/scripts/download_cosmic.py +231 -0
  96. package/bin/skills/dask/SKILL.md +456 -0
  97. package/bin/skills/dask/references/arrays.md +497 -0
  98. package/bin/skills/dask/references/bags.md +468 -0
  99. package/bin/skills/dask/references/best-practices.md +277 -0
  100. package/bin/skills/dask/references/dataframes.md +368 -0
  101. package/bin/skills/dask/references/futures.md +541 -0
  102. package/bin/skills/dask/references/schedulers.md +504 -0
  103. package/bin/skills/datacommons-client/SKILL.md +255 -0
  104. package/bin/skills/datacommons-client/references/getting_started.md +417 -0
  105. package/bin/skills/datacommons-client/references/node.md +250 -0
  106. package/bin/skills/datacommons-client/references/observation.md +185 -0
  107. package/bin/skills/datacommons-client/references/resolve.md +246 -0
  108. package/bin/skills/datamol/SKILL.md +706 -0
  109. package/bin/skills/datamol/references/conformers_module.md +131 -0
  110. package/bin/skills/datamol/references/core_api.md +130 -0
  111. package/bin/skills/datamol/references/descriptors_viz.md +195 -0
  112. package/bin/skills/datamol/references/fragments_scaffolds.md +174 -0
  113. package/bin/skills/datamol/references/io_module.md +109 -0
  114. package/bin/skills/datamol/references/reactions_data.md +218 -0
  115. package/bin/skills/deepchem/SKILL.md +597 -0
  116. package/bin/skills/deepchem/references/api_reference.md +303 -0
  117. package/bin/skills/deepchem/references/workflows.md +491 -0
  118. package/bin/skills/deepchem/scripts/graph_neural_network.py +338 -0
  119. package/bin/skills/deepchem/scripts/predict_solubility.py +224 -0
  120. package/bin/skills/deepchem/scripts/transfer_learning.py +375 -0
  121. package/bin/skills/deeptools/SKILL.md +531 -0
  122. package/bin/skills/deeptools/assets/quick_reference.md +58 -0
  123. package/bin/skills/deeptools/references/effective_genome_sizes.md +116 -0
  124. package/bin/skills/deeptools/references/normalization_methods.md +410 -0
  125. package/bin/skills/deeptools/references/tools_reference.md +533 -0
  126. package/bin/skills/deeptools/references/workflows.md +474 -0
  127. package/bin/skills/deeptools/scripts/validate_files.py +195 -0
  128. package/bin/skills/deeptools/scripts/workflow_generator.py +454 -0
  129. package/bin/skills/denario/SKILL.md +215 -0
  130. package/bin/skills/denario/references/examples.md +494 -0
  131. package/bin/skills/denario/references/installation.md +213 -0
  132. package/bin/skills/denario/references/llm_configuration.md +265 -0
  133. package/bin/skills/denario/references/research_pipeline.md +471 -0
  134. package/bin/skills/diffdock/SKILL.md +483 -0
  135. package/bin/skills/diffdock/assets/batch_template.csv +4 -0
  136. package/bin/skills/diffdock/assets/custom_inference_config.yaml +90 -0
  137. package/bin/skills/diffdock/references/confidence_and_limitations.md +182 -0
  138. package/bin/skills/diffdock/references/parameters_reference.md +163 -0
  139. package/bin/skills/diffdock/references/workflows_examples.md +392 -0
  140. package/bin/skills/diffdock/scripts/analyze_results.py +334 -0
  141. package/bin/skills/diffdock/scripts/prepare_batch_csv.py +254 -0
  142. package/bin/skills/diffdock/scripts/setup_check.py +278 -0
  143. package/bin/skills/dnanexus-integration/SKILL.md +383 -0
  144. package/bin/skills/dnanexus-integration/references/app-development.md +247 -0
  145. package/bin/skills/dnanexus-integration/references/configuration.md +646 -0
  146. package/bin/skills/dnanexus-integration/references/data-operations.md +400 -0
  147. package/bin/skills/dnanexus-integration/references/job-execution.md +412 -0
  148. package/bin/skills/dnanexus-integration/references/python-sdk.md +523 -0
  149. package/bin/skills/document-skills/docx/LICENSE.txt +30 -0
  150. package/bin/skills/document-skills/docx/SKILL.md +233 -0
  151. package/bin/skills/document-skills/docx/docx-js.md +350 -0
  152. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/dml-chart.xsd +1499 -0
  153. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/dml-chartDrawing.xsd +146 -0
  154. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/dml-diagram.xsd +1085 -0
  155. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/dml-lockedCanvas.xsd +11 -0
  156. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/dml-main.xsd +3081 -0
  157. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/dml-picture.xsd +23 -0
  158. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/dml-spreadsheetDrawing.xsd +185 -0
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  160. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/pml.xsd +1676 -0
  161. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/shared-additionalCharacteristics.xsd +28 -0
  162. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/shared-bibliography.xsd +144 -0
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  805. package/bin/skills/uniprot-database/references/api_examples.md +413 -0
  806. package/bin/skills/uniprot-database/references/api_fields.md +275 -0
  807. package/bin/skills/uniprot-database/references/id_mapping_databases.md +285 -0
  808. package/bin/skills/uniprot-database/references/query_syntax.md +256 -0
  809. package/bin/skills/uniprot-database/scripts/uniprot_client.py +341 -0
  810. package/bin/skills/uspto-database/SKILL.md +607 -0
  811. package/bin/skills/uspto-database/references/additional_apis.md +394 -0
  812. package/bin/skills/uspto-database/references/patentsearch_api.md +266 -0
  813. package/bin/skills/uspto-database/references/peds_api.md +212 -0
  814. package/bin/skills/uspto-database/references/trademark_api.md +358 -0
  815. package/bin/skills/uspto-database/scripts/patent_search.py +290 -0
  816. package/bin/skills/uspto-database/scripts/peds_client.py +285 -0
  817. package/bin/skills/uspto-database/scripts/trademark_client.py +311 -0
  818. package/bin/skills/vaex/SKILL.md +182 -0
  819. package/bin/skills/vaex/references/core_dataframes.md +367 -0
  820. package/bin/skills/vaex/references/data_processing.md +555 -0
  821. package/bin/skills/vaex/references/io_operations.md +703 -0
  822. package/bin/skills/vaex/references/machine_learning.md +728 -0
  823. package/bin/skills/vaex/references/performance.md +571 -0
  824. package/bin/skills/vaex/references/visualization.md +613 -0
  825. package/bin/skills/zarr-python/SKILL.md +779 -0
  826. package/bin/skills/zarr-python/references/api_reference.md +515 -0
  827. package/bin/skills/zinc-database/SKILL.md +404 -0
  828. package/bin/skills/zinc-database/references/api_reference.md +692 -0
  829. package/bin/synsc +0 -0
  830. package/package.json +1 -1
@@ -0,0 +1,352 @@
1
+ # DICOM Transfer Syntaxes Reference
2
+
3
+ This document provides a comprehensive reference for DICOM transfer syntaxes and compression formats. Transfer syntaxes define how DICOM data is encoded, including byte ordering, compression method, and other encoding rules.
4
+
5
+ ## Overview
6
+
7
+ A Transfer Syntax UID specifies:
8
+ 1. **Byte ordering**: Little Endian or Big Endian
9
+ 2. **Value Representation (VR)**: Implicit or Explicit
10
+ 3. **Compression**: None, or specific compression algorithm
11
+
12
+ ## Uncompressed Transfer Syntaxes
13
+
14
+ ### Implicit VR Little Endian (1.2.840.10008.1.2)
15
+ - **Default** transfer syntax
16
+ - Value Representations are implicit (not explicitly encoded)
17
+ - Little Endian byte ordering
18
+ - **Pydicom constant**: `pydicom.uid.ImplicitVRLittleEndian`
19
+
20
+ **Usage:**
21
+ ```python
22
+ import pydicom
23
+ ds.file_meta.TransferSyntaxUID = pydicom.uid.ImplicitVRLittleEndian
24
+ ```
25
+
26
+ ### Explicit VR Little Endian (1.2.840.10008.1.2.1)
27
+ - **Most common** transfer syntax
28
+ - Value Representations are explicit
29
+ - Little Endian byte ordering
30
+ - **Pydicom constant**: `pydicom.uid.ExplicitVRLittleEndian`
31
+
32
+ **Usage:**
33
+ ```python
34
+ ds.file_meta.TransferSyntaxUID = pydicom.uid.ExplicitVRLittleEndian
35
+ ```
36
+
37
+ ### Explicit VR Big Endian (1.2.840.10008.1.2.2) - RETIRED
38
+ - Value Representations are explicit
39
+ - Big Endian byte ordering
40
+ - **Deprecated** - not recommended for new implementations
41
+ - **Pydicom constant**: `pydicom.uid.ExplicitVRBigEndian`
42
+
43
+ ## JPEG Compression
44
+
45
+ ### JPEG Baseline (Process 1) (1.2.840.10008.1.2.4.50)
46
+ - **Lossy** compression
47
+ - 8-bit samples only
48
+ - Most widely supported JPEG format
49
+ - **Pydicom constant**: `pydicom.uid.JPEGBaseline8Bit`
50
+
51
+ **Dependencies:** Requires `pylibjpeg` or `pillow`
52
+
53
+ **Usage:**
54
+ ```python
55
+ # Compress
56
+ ds.compress(pydicom.uid.JPEGBaseline8Bit)
57
+
58
+ # Decompress
59
+ ds.decompress()
60
+ ```
61
+
62
+ ### JPEG Extended (Process 2 & 4) (1.2.840.10008.1.2.4.51)
63
+ - **Lossy** compression
64
+ - 8-bit and 12-bit samples
65
+ - **Pydicom constant**: `pydicom.uid.JPEGExtended12Bit`
66
+
67
+ ### JPEG Lossless, Non-Hierarchical (Process 14) (1.2.840.10008.1.2.4.57)
68
+ - **Lossless** compression
69
+ - First-Order Prediction
70
+ - **Pydicom constant**: `pydicom.uid.JPEGLossless`
71
+
72
+ **Dependencies:** Requires `pylibjpeg-libjpeg` or `gdcm`
73
+
74
+ ### JPEG Lossless, Non-Hierarchical, First-Order Prediction (1.2.840.10008.1.2.4.70)
75
+ - **Lossless** compression
76
+ - Uses Process 14 Selection Value 1
77
+ - **Pydicom constant**: `pydicom.uid.JPEGLosslessSV1`
78
+
79
+ **Usage:**
80
+ ```python
81
+ # Compress to JPEG Lossless
82
+ ds.compress(pydicom.uid.JPEGLossless)
83
+ ```
84
+
85
+ ### JPEG-LS Lossless (1.2.840.10008.1.2.4.80)
86
+ - **Lossless** compression
87
+ - Low complexity, good compression
88
+ - **Pydicom constant**: `pydicom.uid.JPEGLSLossless`
89
+
90
+ **Dependencies:** Requires `pylibjpeg-libjpeg` or `gdcm`
91
+
92
+ ### JPEG-LS Lossy (Near-Lossless) (1.2.840.10008.1.2.4.81)
93
+ - **Near-lossless** compression
94
+ - Allows controlled loss of precision
95
+ - **Pydicom constant**: `pydicom.uid.JPEGLSNearLossless`
96
+
97
+ ## JPEG 2000 Compression
98
+
99
+ ### JPEG 2000 Lossless Only (1.2.840.10008.1.2.4.90)
100
+ - **Lossless** compression
101
+ - Wavelet-based compression
102
+ - Better compression than JPEG Lossless
103
+ - **Pydicom constant**: `pydicom.uid.JPEG2000Lossless`
104
+
105
+ **Dependencies:** Requires `pylibjpeg-openjpeg`, `gdcm`, or `pillow`
106
+
107
+ **Usage:**
108
+ ```python
109
+ # Compress to JPEG 2000 Lossless
110
+ ds.compress(pydicom.uid.JPEG2000Lossless)
111
+ ```
112
+
113
+ ### JPEG 2000 (1.2.840.10008.1.2.4.91)
114
+ - **Lossy or lossless** compression
115
+ - Wavelet-based compression
116
+ - High quality at low bit rates
117
+ - **Pydicom constant**: `pydicom.uid.JPEG2000`
118
+
119
+ **Dependencies:** Requires `pylibjpeg-openjpeg`, `gdcm`, or `pillow`
120
+
121
+ ### JPEG 2000 Part 2 Multi-component Lossless (1.2.840.10008.1.2.4.92)
122
+ - **Lossless** compression
123
+ - Supports multi-component images
124
+ - **Pydicom constant**: `pydicom.uid.JPEG2000MCLossless`
125
+
126
+ ### JPEG 2000 Part 2 Multi-component (1.2.840.10008.1.2.4.93)
127
+ - **Lossy or lossless** compression
128
+ - Supports multi-component images
129
+ - **Pydicom constant**: `pydicom.uid.JPEG2000MC`
130
+
131
+ ## RLE Compression
132
+
133
+ ### RLE Lossless (1.2.840.10008.1.2.5)
134
+ - **Lossless** compression
135
+ - Run-Length Encoding
136
+ - Simple, fast algorithm
137
+ - Good for images with repeated values
138
+ - **Pydicom constant**: `pydicom.uid.RLELossless`
139
+
140
+ **Dependencies:** Built into pydicom (no additional packages needed)
141
+
142
+ **Usage:**
143
+ ```python
144
+ # Compress with RLE
145
+ ds.compress(pydicom.uid.RLELossless)
146
+
147
+ # Decompress
148
+ ds.decompress()
149
+ ```
150
+
151
+ ## Deflated Transfer Syntaxes
152
+
153
+ ### Deflated Explicit VR Little Endian (1.2.840.10008.1.2.1.99)
154
+ - Uses ZLIB compression on entire dataset
155
+ - Not commonly used
156
+ - **Pydicom constant**: `pydicom.uid.DeflatedExplicitVRLittleEndian`
157
+
158
+ ## MPEG Compression
159
+
160
+ ### MPEG2 Main Profile @ Main Level (1.2.840.10008.1.2.4.100)
161
+ - **Lossy** video compression
162
+ - For multi-frame images/videos
163
+ - **Pydicom constant**: `pydicom.uid.MPEG2MPML`
164
+
165
+ ### MPEG2 Main Profile @ High Level (1.2.840.10008.1.2.4.101)
166
+ - **Lossy** video compression
167
+ - Higher resolution than MPML
168
+ - **Pydicom constant**: `pydicom.uid.MPEG2MPHL`
169
+
170
+ ### MPEG-4 AVC/H.264 High Profile (1.2.840.10008.1.2.4.102-106)
171
+ - **Lossy** video compression
172
+ - Various levels (BD, 2D, 3D, Stereo)
173
+ - Modern video codec
174
+
175
+ ## Checking Transfer Syntax
176
+
177
+ ### Identify Current Transfer Syntax
178
+ ```python
179
+ import pydicom
180
+
181
+ ds = pydicom.dcmread('image.dcm')
182
+
183
+ # Get transfer syntax UID
184
+ ts_uid = ds.file_meta.TransferSyntaxUID
185
+ print(f"Transfer Syntax UID: {ts_uid}")
186
+
187
+ # Get human-readable name
188
+ print(f"Transfer Syntax Name: {ts_uid.name}")
189
+
190
+ # Check if compressed
191
+ print(f"Is compressed: {ts_uid.is_compressed}")
192
+ ```
193
+
194
+ ### Common Checks
195
+ ```python
196
+ # Check if little endian
197
+ if ts_uid.is_little_endian:
198
+ print("Little Endian")
199
+
200
+ # Check if implicit VR
201
+ if ts_uid.is_implicit_VR:
202
+ print("Implicit VR")
203
+
204
+ # Check compression type
205
+ if 'JPEG' in ts_uid.name:
206
+ print("JPEG compressed")
207
+ elif 'JPEG2000' in ts_uid.name:
208
+ print("JPEG 2000 compressed")
209
+ elif 'RLE' in ts_uid.name:
210
+ print("RLE compressed")
211
+ ```
212
+
213
+ ## Decompression
214
+
215
+ ### Automatic Decompression
216
+ Pydicom can automatically decompress pixel data when accessing `pixel_array`:
217
+
218
+ ```python
219
+ import pydicom
220
+
221
+ # Read compressed DICOM
222
+ ds = pydicom.dcmread('compressed.dcm')
223
+
224
+ # Pixel data is automatically decompressed
225
+ pixel_array = ds.pixel_array # Decompresses if needed
226
+ ```
227
+
228
+ ### Manual Decompression
229
+ ```python
230
+ import pydicom
231
+
232
+ ds = pydicom.dcmread('compressed.dcm')
233
+
234
+ # Decompress in-place
235
+ ds.decompress()
236
+
237
+ # Now save as uncompressed
238
+ ds.save_as('uncompressed.dcm', write_like_original=False)
239
+ ```
240
+
241
+ ## Compression
242
+
243
+ ### Compressing DICOM Files
244
+ ```python
245
+ import pydicom
246
+
247
+ ds = pydicom.dcmread('uncompressed.dcm')
248
+
249
+ # Compress using JPEG 2000 Lossless
250
+ ds.compress(pydicom.uid.JPEG2000Lossless)
251
+ ds.save_as('compressed_j2k.dcm')
252
+
253
+ # Compress using RLE Lossless (no additional dependencies)
254
+ ds.compress(pydicom.uid.RLELossless)
255
+ ds.save_as('compressed_rle.dcm')
256
+
257
+ # Compress using JPEG Baseline (lossy)
258
+ ds.compress(pydicom.uid.JPEGBaseline8Bit)
259
+ ds.save_as('compressed_jpeg.dcm')
260
+ ```
261
+
262
+ ### Compression with Custom Encoding Parameters
263
+ ```python
264
+ import pydicom
265
+ from pydicom.encoders import JPEGLSLosslessEncoder
266
+
267
+ ds = pydicom.dcmread('uncompressed.dcm')
268
+
269
+ # Compress with custom parameters
270
+ ds.compress(pydicom.uid.JPEGLSLossless, encoding_plugin='pylibjpeg')
271
+ ```
272
+
273
+ ## Installing Compression Handlers
274
+
275
+ Different transfer syntaxes require different Python packages:
276
+
277
+ ### JPEG Baseline/Extended
278
+ ```bash
279
+ pip install pylibjpeg pylibjpeg-libjpeg
280
+ # Or
281
+ pip install pillow
282
+ ```
283
+
284
+ ### JPEG Lossless/JPEG-LS
285
+ ```bash
286
+ pip install pylibjpeg pylibjpeg-libjpeg
287
+ # Or
288
+ pip install python-gdcm
289
+ ```
290
+
291
+ ### JPEG 2000
292
+ ```bash
293
+ pip install pylibjpeg pylibjpeg-openjpeg
294
+ # Or
295
+ pip install python-gdcm
296
+ # Or
297
+ pip install pillow
298
+ ```
299
+
300
+ ### RLE
301
+ No additional packages needed - built into pydicom
302
+
303
+ ### Comprehensive Installation
304
+ ```bash
305
+ # Install all common handlers
306
+ pip install pylibjpeg pylibjpeg-libjpeg pylibjpeg-openjpeg python-gdcm
307
+ ```
308
+
309
+ ## Checking Available Handlers
310
+
311
+ ```python
312
+ import pydicom
313
+
314
+ # List available pixel data handlers
315
+ from pydicom.pixel_data_handlers.util import get_pixel_data_handlers
316
+ handlers = get_pixel_data_handlers()
317
+
318
+ print("Available handlers:")
319
+ for handler in handlers:
320
+ print(f" - {handler.__name__}")
321
+ ```
322
+
323
+ ## Best Practices
324
+
325
+ 1. **Use Explicit VR Little Endian** for maximum compatibility when creating new files
326
+ 2. **Use JPEG 2000 Lossless** for good compression with no quality loss
327
+ 3. **Use RLE Lossless** if you can't install additional dependencies
328
+ 4. **Check Transfer Syntax** before processing to ensure you have the right handlers
329
+ 5. **Test decompression** before deploying to ensure all required packages are installed
330
+ 6. **Preserve original** transfer syntax when possible using `write_like_original=True`
331
+ 7. **Consider file size** vs. quality tradeoffs when choosing lossy compression
332
+ 8. **Use lossless compression** for diagnostic images to maintain clinical quality
333
+
334
+ ## Common Issues
335
+
336
+ ### Issue: "Unable to decode pixel data"
337
+ **Cause:** Missing compression handler
338
+ **Solution:** Install the appropriate package (see Installing Compression Handlers above)
339
+
340
+ ### Issue: "Unsupported Transfer Syntax"
341
+ **Cause:** Rare or unsupported compression format
342
+ **Solution:** Try installing `python-gdcm` which supports more formats
343
+
344
+ ### Issue: "Pixel data decompressed but looks wrong"
345
+ **Cause:** May need to apply VOI LUT or rescale
346
+ **Solution:** Use `apply_voi_lut()` or apply `RescaleSlope`/`RescaleIntercept`
347
+
348
+ ## References
349
+
350
+ - DICOM Standard Part 5 (Data Structures and Encoding): https://dicom.nema.org/medical/dicom/current/output/chtml/part05/PS3.5.html
351
+ - Pydicom Transfer Syntax Documentation: https://pydicom.github.io/pydicom/stable/guides/user/transfer_syntaxes.html
352
+ - Pydicom Compression Guide: https://pydicom.github.io/pydicom/stable/old/image_data_compression.html
@@ -0,0 +1,137 @@
1
+ #!/usr/bin/env python3
2
+ """
3
+ Anonymize DICOM files by removing or replacing Protected Health Information (PHI).
4
+
5
+ Usage:
6
+ python anonymize_dicom.py input.dcm output.dcm
7
+ python anonymize_dicom.py input.dcm output.dcm --patient-id ANON001
8
+ """
9
+
10
+ import argparse
11
+ import sys
12
+ from pathlib import Path
13
+
14
+ try:
15
+ import pydicom
16
+ except ImportError:
17
+ print("Error: pydicom is not installed. Install it with: pip install pydicom")
18
+ sys.exit(1)
19
+
20
+
21
+ # Tags commonly containing PHI (Protected Health Information)
22
+ PHI_TAGS = [
23
+ 'PatientName', 'PatientID', 'PatientBirthDate', 'PatientBirthTime',
24
+ 'PatientSex', 'PatientAge', 'PatientSize', 'PatientWeight',
25
+ 'PatientAddress', 'PatientTelephoneNumbers', 'PatientMotherBirthName',
26
+ 'MilitaryRank', 'EthnicGroup', 'Occupation', 'PatientComments',
27
+ 'InstitutionName', 'InstitutionAddress', 'InstitutionalDepartmentName',
28
+ 'ReferringPhysicianName', 'ReferringPhysicianAddress',
29
+ 'ReferringPhysicianTelephoneNumbers', 'ReferringPhysicianIdentificationSequence',
30
+ 'PerformingPhysicianName', 'PerformingPhysicianIdentificationSequence',
31
+ 'OperatorsName', 'PhysiciansOfRecord', 'PhysiciansOfRecordIdentificationSequence',
32
+ 'NameOfPhysiciansReadingStudy', 'PhysiciansReadingStudyIdentificationSequence',
33
+ 'StudyDescription', 'SeriesDescription', 'AdmittingDiagnosesDescription',
34
+ 'DerivationDescription', 'RequestingPhysician', 'RequestingService',
35
+ 'RequestedProcedureDescription', 'ScheduledPerformingPhysicianName',
36
+ 'PerformedLocation', 'PerformedStationName',
37
+ ]
38
+
39
+
40
+ def anonymize_dicom(input_path, output_path, patient_id='ANONYMOUS', patient_name='ANONYMOUS'):
41
+ """
42
+ Anonymize a DICOM file by removing or replacing PHI.
43
+
44
+ Args:
45
+ input_path: Path to input DICOM file
46
+ output_path: Path to output anonymized DICOM file
47
+ patient_id: Replacement patient ID (default: 'ANONYMOUS')
48
+ patient_name: Replacement patient name (default: 'ANONYMOUS')
49
+ """
50
+ try:
51
+ # Read DICOM file
52
+ ds = pydicom.dcmread(input_path)
53
+
54
+ # Track what was anonymized
55
+ anonymized = []
56
+
57
+ # Remove or replace sensitive data
58
+ for tag in PHI_TAGS:
59
+ if hasattr(ds, tag):
60
+ if tag == 'PatientName':
61
+ ds.PatientName = patient_name
62
+ anonymized.append(f"{tag}: replaced with '{patient_name}'")
63
+ elif tag == 'PatientID':
64
+ ds.PatientID = patient_id
65
+ anonymized.append(f"{tag}: replaced with '{patient_id}'")
66
+ elif tag == 'PatientBirthDate':
67
+ ds.PatientBirthDate = '19000101'
68
+ anonymized.append(f"{tag}: replaced with '19000101'")
69
+ else:
70
+ delattr(ds, tag)
71
+ anonymized.append(f"{tag}: removed")
72
+
73
+ # Anonymize UIDs if present (optional - maintains referential integrity)
74
+ # Uncomment if you want to anonymize UIDs as well
75
+ # if hasattr(ds, 'StudyInstanceUID'):
76
+ # ds.StudyInstanceUID = pydicom.uid.generate_uid()
77
+ # if hasattr(ds, 'SeriesInstanceUID'):
78
+ # ds.SeriesInstanceUID = pydicom.uid.generate_uid()
79
+ # if hasattr(ds, 'SOPInstanceUID'):
80
+ # ds.SOPInstanceUID = pydicom.uid.generate_uid()
81
+
82
+ # Save anonymized file
83
+ ds.save_as(output_path)
84
+
85
+ return True, anonymized
86
+
87
+ except Exception as e:
88
+ return False, str(e)
89
+
90
+
91
+ def main():
92
+ parser = argparse.ArgumentParser(
93
+ description='Anonymize DICOM files by removing or replacing PHI',
94
+ formatter_class=argparse.RawDescriptionHelpFormatter,
95
+ epilog="""
96
+ Examples:
97
+ python anonymize_dicom.py input.dcm output.dcm
98
+ python anonymize_dicom.py input.dcm output.dcm --patient-id ANON001
99
+ python anonymize_dicom.py input.dcm output.dcm --patient-id ANON001 --patient-name "Anonymous^Patient"
100
+ """
101
+ )
102
+
103
+ parser.add_argument('input', type=str, help='Input DICOM file')
104
+ parser.add_argument('output', type=str, help='Output anonymized DICOM file')
105
+ parser.add_argument('--patient-id', type=str, default='ANONYMOUS',
106
+ help='Replacement patient ID (default: ANONYMOUS)')
107
+ parser.add_argument('--patient-name', type=str, default='ANONYMOUS',
108
+ help='Replacement patient name (default: ANONYMOUS)')
109
+ parser.add_argument('-v', '--verbose', action='store_true',
110
+ help='Show detailed anonymization information')
111
+
112
+ args = parser.parse_args()
113
+
114
+ # Validate input file exists
115
+ input_path = Path(args.input)
116
+ if not input_path.exists():
117
+ print(f"Error: Input file '{args.input}' not found")
118
+ sys.exit(1)
119
+
120
+ # Anonymize the file
121
+ print(f"Anonymizing: {args.input}")
122
+ success, result = anonymize_dicom(args.input, args.output,
123
+ args.patient_id, args.patient_name)
124
+
125
+ if success:
126
+ print(f"✓ Successfully anonymized DICOM file: {args.output}")
127
+ if args.verbose:
128
+ print(f"\nAnonymized {len(result)} fields:")
129
+ for item in result:
130
+ print(f" - {item}")
131
+ else:
132
+ print(f"✗ Error: {result}")
133
+ sys.exit(1)
134
+
135
+
136
+ if __name__ == '__main__':
137
+ main()
@@ -0,0 +1,172 @@
1
+ #!/usr/bin/env python3
2
+ """
3
+ Convert DICOM files to common image formats (PNG, JPEG, TIFF).
4
+
5
+ Usage:
6
+ python dicom_to_image.py input.dcm output.png
7
+ python dicom_to_image.py input.dcm output.jpg --format JPEG
8
+ python dicom_to_image.py input.dcm output.tiff --apply-windowing
9
+ """
10
+
11
+ import argparse
12
+ import sys
13
+ from pathlib import Path
14
+
15
+ try:
16
+ import pydicom
17
+ import numpy as np
18
+ from PIL import Image
19
+ except ImportError as e:
20
+ print(f"Error: Required package not installed: {e}")
21
+ print("Install with: pip install pydicom pillow numpy")
22
+ sys.exit(1)
23
+
24
+
25
+ def apply_windowing(pixel_array, ds):
26
+ """Apply VOI LUT windowing if available."""
27
+ try:
28
+ from pydicom.pixel_data_handlers.util import apply_voi_lut
29
+ return apply_voi_lut(pixel_array, ds)
30
+ except (ImportError, AttributeError):
31
+ return pixel_array
32
+
33
+
34
+ def normalize_to_uint8(pixel_array):
35
+ """Normalize pixel array to uint8 (0-255) range."""
36
+ if pixel_array.dtype == np.uint8:
37
+ return pixel_array
38
+
39
+ # Normalize to 0-1 range
40
+ pix_min = pixel_array.min()
41
+ pix_max = pixel_array.max()
42
+
43
+ if pix_max > pix_min:
44
+ normalized = (pixel_array - pix_min) / (pix_max - pix_min)
45
+ else:
46
+ normalized = np.zeros_like(pixel_array, dtype=float)
47
+
48
+ # Scale to 0-255
49
+ return (normalized * 255).astype(np.uint8)
50
+
51
+
52
+ def convert_dicom_to_image(input_path, output_path, image_format='PNG',
53
+ apply_window=False, frame=0):
54
+ """
55
+ Convert DICOM file to standard image format.
56
+
57
+ Args:
58
+ input_path: Path to input DICOM file
59
+ output_path: Path to output image file
60
+ image_format: Output format (PNG, JPEG, TIFF, etc.)
61
+ apply_window: Whether to apply VOI LUT windowing
62
+ frame: Frame number for multi-frame DICOM files
63
+ """
64
+ try:
65
+ # Read DICOM file
66
+ ds = pydicom.dcmread(input_path)
67
+
68
+ # Get pixel array
69
+ pixel_array = ds.pixel_array
70
+
71
+ # Handle multi-frame DICOM
72
+ if len(pixel_array.shape) == 3 and pixel_array.shape[0] > 1:
73
+ if frame >= pixel_array.shape[0]:
74
+ return False, f"Frame {frame} out of range (0-{pixel_array.shape[0]-1})"
75
+ pixel_array = pixel_array[frame]
76
+ print(f"Extracting frame {frame} of {ds.NumberOfFrames}")
77
+
78
+ # Apply windowing if requested
79
+ if apply_window and hasattr(ds, 'WindowCenter'):
80
+ pixel_array = apply_windowing(pixel_array, ds)
81
+
82
+ # Handle color images
83
+ if len(pixel_array.shape) == 3 and pixel_array.shape[2] in [3, 4]:
84
+ # RGB or RGBA image
85
+ if ds.PhotometricInterpretation in ['YBR_FULL', 'YBR_FULL_422']:
86
+ # Convert from YBR to RGB
87
+ try:
88
+ from pydicom.pixel_data_handlers.util import convert_color_space
89
+ pixel_array = convert_color_space(pixel_array,
90
+ ds.PhotometricInterpretation, 'RGB')
91
+ except ImportError:
92
+ print("Warning: Could not convert color space, using as-is")
93
+
94
+ image = Image.fromarray(pixel_array)
95
+ else:
96
+ # Grayscale image - normalize to uint8
97
+ pixel_array = normalize_to_uint8(pixel_array)
98
+ image = Image.fromarray(pixel_array, mode='L')
99
+
100
+ # Save image
101
+ image.save(output_path, format=image_format)
102
+
103
+ return True, {
104
+ 'shape': ds.pixel_array.shape,
105
+ 'modality': ds.Modality if hasattr(ds, 'Modality') else 'Unknown',
106
+ 'bits_allocated': ds.BitsAllocated if hasattr(ds, 'BitsAllocated') else 'Unknown',
107
+ }
108
+
109
+ except Exception as e:
110
+ return False, str(e)
111
+
112
+
113
+ def main():
114
+ parser = argparse.ArgumentParser(
115
+ description='Convert DICOM files to common image formats',
116
+ formatter_class=argparse.RawDescriptionHelpFormatter,
117
+ epilog="""
118
+ Examples:
119
+ python dicom_to_image.py input.dcm output.png
120
+ python dicom_to_image.py input.dcm output.jpg --format JPEG
121
+ python dicom_to_image.py input.dcm output.tiff --apply-windowing
122
+ python dicom_to_image.py multiframe.dcm frame5.png --frame 5
123
+ """
124
+ )
125
+
126
+ parser.add_argument('input', type=str, help='Input DICOM file')
127
+ parser.add_argument('output', type=str, help='Output image file')
128
+ parser.add_argument('--format', type=str, choices=['PNG', 'JPEG', 'TIFF', 'BMP'],
129
+ help='Output image format (default: inferred from extension)')
130
+ parser.add_argument('--apply-windowing', action='store_true',
131
+ help='Apply VOI LUT windowing if available')
132
+ parser.add_argument('--frame', type=int, default=0,
133
+ help='Frame number for multi-frame DICOM files (default: 0)')
134
+ parser.add_argument('-v', '--verbose', action='store_true',
135
+ help='Show detailed conversion information')
136
+
137
+ args = parser.parse_args()
138
+
139
+ # Validate input file exists
140
+ input_path = Path(args.input)
141
+ if not input_path.exists():
142
+ print(f"Error: Input file '{args.input}' not found")
143
+ sys.exit(1)
144
+
145
+ # Determine output format
146
+ if args.format:
147
+ image_format = args.format
148
+ else:
149
+ # Infer from extension
150
+ ext = Path(args.output).suffix.upper().lstrip('.')
151
+ image_format = ext if ext in ['PNG', 'JPEG', 'JPG', 'TIFF', 'BMP'] else 'PNG'
152
+
153
+ # Convert the file
154
+ print(f"Converting: {args.input} -> {args.output}")
155
+ success, result = convert_dicom_to_image(args.input, args.output,
156
+ image_format, args.apply_windowing,
157
+ args.frame)
158
+
159
+ if success:
160
+ print(f"✓ Successfully converted to {image_format}")
161
+ if args.verbose:
162
+ print(f"\nImage information:")
163
+ print(f" - Shape: {result['shape']}")
164
+ print(f" - Modality: {result['modality']}")
165
+ print(f" - Bits Allocated: {result['bits_allocated']}")
166
+ else:
167
+ print(f"✗ Error: {result}")
168
+ sys.exit(1)
169
+
170
+
171
+ if __name__ == '__main__':
172
+ main()