@synsci/cli-darwin-x64-baseline 1.1.76 → 1.1.78

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (830) hide show
  1. package/bin/skills/adaptyv/SKILL.md +114 -0
  2. package/bin/skills/adaptyv/reference/api_reference.md +308 -0
  3. package/bin/skills/adaptyv/reference/examples.md +913 -0
  4. package/bin/skills/adaptyv/reference/experiments.md +360 -0
  5. package/bin/skills/adaptyv/reference/protein_optimization.md +637 -0
  6. package/bin/skills/aeon/SKILL.md +374 -0
  7. package/bin/skills/aeon/references/anomaly_detection.md +154 -0
  8. package/bin/skills/aeon/references/classification.md +144 -0
  9. package/bin/skills/aeon/references/clustering.md +123 -0
  10. package/bin/skills/aeon/references/datasets_benchmarking.md +387 -0
  11. package/bin/skills/aeon/references/distances.md +256 -0
  12. package/bin/skills/aeon/references/forecasting.md +140 -0
  13. package/bin/skills/aeon/references/networks.md +289 -0
  14. package/bin/skills/aeon/references/regression.md +118 -0
  15. package/bin/skills/aeon/references/segmentation.md +163 -0
  16. package/bin/skills/aeon/references/similarity_search.md +187 -0
  17. package/bin/skills/aeon/references/transformations.md +246 -0
  18. package/bin/skills/alphafold-database/SKILL.md +513 -0
  19. package/bin/skills/alphafold-database/references/api_reference.md +423 -0
  20. package/bin/skills/anndata/SKILL.md +400 -0
  21. package/bin/skills/anndata/references/best_practices.md +525 -0
  22. package/bin/skills/anndata/references/concatenation.md +396 -0
  23. package/bin/skills/anndata/references/data_structure.md +314 -0
  24. package/bin/skills/anndata/references/io_operations.md +404 -0
  25. package/bin/skills/anndata/references/manipulation.md +516 -0
  26. package/bin/skills/arboreto/SKILL.md +243 -0
  27. package/bin/skills/arboreto/references/algorithms.md +138 -0
  28. package/bin/skills/arboreto/references/basic_inference.md +151 -0
  29. package/bin/skills/arboreto/references/distributed_computing.md +242 -0
  30. package/bin/skills/arboreto/scripts/basic_grn_inference.py +97 -0
  31. package/bin/skills/astropy/SKILL.md +331 -0
  32. package/bin/skills/astropy/references/coordinates.md +273 -0
  33. package/bin/skills/astropy/references/cosmology.md +307 -0
  34. package/bin/skills/astropy/references/fits.md +396 -0
  35. package/bin/skills/astropy/references/tables.md +489 -0
  36. package/bin/skills/astropy/references/time.md +404 -0
  37. package/bin/skills/astropy/references/units.md +178 -0
  38. package/bin/skills/astropy/references/wcs_and_other_modules.md +373 -0
  39. package/bin/skills/benchling-integration/SKILL.md +480 -0
  40. package/bin/skills/benchling-integration/references/api_endpoints.md +883 -0
  41. package/bin/skills/benchling-integration/references/authentication.md +379 -0
  42. package/bin/skills/benchling-integration/references/sdk_reference.md +774 -0
  43. package/bin/skills/biopython/SKILL.md +443 -0
  44. package/bin/skills/biopython/references/advanced.md +577 -0
  45. package/bin/skills/biopython/references/alignment.md +362 -0
  46. package/bin/skills/biopython/references/blast.md +455 -0
  47. package/bin/skills/biopython/references/databases.md +484 -0
  48. package/bin/skills/biopython/references/phylogenetics.md +566 -0
  49. package/bin/skills/biopython/references/sequence_io.md +285 -0
  50. package/bin/skills/biopython/references/structure.md +564 -0
  51. package/bin/skills/biorxiv-database/SKILL.md +483 -0
  52. package/bin/skills/biorxiv-database/references/api_reference.md +280 -0
  53. package/bin/skills/biorxiv-database/scripts/biorxiv_search.py +445 -0
  54. package/bin/skills/bioservices/SKILL.md +361 -0
  55. package/bin/skills/bioservices/references/identifier_mapping.md +685 -0
  56. package/bin/skills/bioservices/references/services_reference.md +636 -0
  57. package/bin/skills/bioservices/references/workflow_patterns.md +811 -0
  58. package/bin/skills/bioservices/scripts/batch_id_converter.py +347 -0
  59. package/bin/skills/bioservices/scripts/compound_cross_reference.py +378 -0
  60. package/bin/skills/bioservices/scripts/pathway_analysis.py +309 -0
  61. package/bin/skills/bioservices/scripts/protein_analysis_workflow.py +408 -0
  62. package/bin/skills/brenda-database/SKILL.md +719 -0
  63. package/bin/skills/brenda-database/references/api_reference.md +537 -0
  64. package/bin/skills/brenda-database/scripts/brenda_queries.py +844 -0
  65. package/bin/skills/brenda-database/scripts/brenda_visualization.py +772 -0
  66. package/bin/skills/brenda-database/scripts/enzyme_pathway_builder.py +1053 -0
  67. package/bin/skills/cellxgene-census/SKILL.md +511 -0
  68. package/bin/skills/cellxgene-census/references/census_schema.md +182 -0
  69. package/bin/skills/cellxgene-census/references/common_patterns.md +351 -0
  70. package/bin/skills/chembl-database/SKILL.md +389 -0
  71. package/bin/skills/chembl-database/references/api_reference.md +272 -0
  72. package/bin/skills/chembl-database/scripts/example_queries.py +278 -0
  73. package/bin/skills/cirq/SKILL.md +346 -0
  74. package/bin/skills/cirq/references/building.md +307 -0
  75. package/bin/skills/cirq/references/experiments.md +572 -0
  76. package/bin/skills/cirq/references/hardware.md +515 -0
  77. package/bin/skills/cirq/references/noise.md +515 -0
  78. package/bin/skills/cirq/references/simulation.md +350 -0
  79. package/bin/skills/cirq/references/transformation.md +416 -0
  80. package/bin/skills/clinicaltrials-database/SKILL.md +507 -0
  81. package/bin/skills/clinicaltrials-database/references/api_reference.md +358 -0
  82. package/bin/skills/clinicaltrials-database/scripts/query_clinicaltrials.py +215 -0
  83. package/bin/skills/clinpgx-database/SKILL.md +638 -0
  84. package/bin/skills/clinpgx-database/references/api_reference.md +757 -0
  85. package/bin/skills/clinpgx-database/scripts/query_clinpgx.py +518 -0
  86. package/bin/skills/clinvar-database/SKILL.md +362 -0
  87. package/bin/skills/clinvar-database/references/api_reference.md +227 -0
  88. package/bin/skills/clinvar-database/references/clinical_significance.md +218 -0
  89. package/bin/skills/clinvar-database/references/data_formats.md +358 -0
  90. package/bin/skills/cobrapy/SKILL.md +463 -0
  91. package/bin/skills/cobrapy/references/api_quick_reference.md +655 -0
  92. package/bin/skills/cobrapy/references/workflows.md +593 -0
  93. package/bin/skills/cosmic-database/SKILL.md +336 -0
  94. package/bin/skills/cosmic-database/references/cosmic_data_reference.md +220 -0
  95. package/bin/skills/cosmic-database/scripts/download_cosmic.py +231 -0
  96. package/bin/skills/dask/SKILL.md +456 -0
  97. package/bin/skills/dask/references/arrays.md +497 -0
  98. package/bin/skills/dask/references/bags.md +468 -0
  99. package/bin/skills/dask/references/best-practices.md +277 -0
  100. package/bin/skills/dask/references/dataframes.md +368 -0
  101. package/bin/skills/dask/references/futures.md +541 -0
  102. package/bin/skills/dask/references/schedulers.md +504 -0
  103. package/bin/skills/datacommons-client/SKILL.md +255 -0
  104. package/bin/skills/datacommons-client/references/getting_started.md +417 -0
  105. package/bin/skills/datacommons-client/references/node.md +250 -0
  106. package/bin/skills/datacommons-client/references/observation.md +185 -0
  107. package/bin/skills/datacommons-client/references/resolve.md +246 -0
  108. package/bin/skills/datamol/SKILL.md +706 -0
  109. package/bin/skills/datamol/references/conformers_module.md +131 -0
  110. package/bin/skills/datamol/references/core_api.md +130 -0
  111. package/bin/skills/datamol/references/descriptors_viz.md +195 -0
  112. package/bin/skills/datamol/references/fragments_scaffolds.md +174 -0
  113. package/bin/skills/datamol/references/io_module.md +109 -0
  114. package/bin/skills/datamol/references/reactions_data.md +218 -0
  115. package/bin/skills/deepchem/SKILL.md +597 -0
  116. package/bin/skills/deepchem/references/api_reference.md +303 -0
  117. package/bin/skills/deepchem/references/workflows.md +491 -0
  118. package/bin/skills/deepchem/scripts/graph_neural_network.py +338 -0
  119. package/bin/skills/deepchem/scripts/predict_solubility.py +224 -0
  120. package/bin/skills/deepchem/scripts/transfer_learning.py +375 -0
  121. package/bin/skills/deeptools/SKILL.md +531 -0
  122. package/bin/skills/deeptools/assets/quick_reference.md +58 -0
  123. package/bin/skills/deeptools/references/effective_genome_sizes.md +116 -0
  124. package/bin/skills/deeptools/references/normalization_methods.md +410 -0
  125. package/bin/skills/deeptools/references/tools_reference.md +533 -0
  126. package/bin/skills/deeptools/references/workflows.md +474 -0
  127. package/bin/skills/deeptools/scripts/validate_files.py +195 -0
  128. package/bin/skills/deeptools/scripts/workflow_generator.py +454 -0
  129. package/bin/skills/denario/SKILL.md +215 -0
  130. package/bin/skills/denario/references/examples.md +494 -0
  131. package/bin/skills/denario/references/installation.md +213 -0
  132. package/bin/skills/denario/references/llm_configuration.md +265 -0
  133. package/bin/skills/denario/references/research_pipeline.md +471 -0
  134. package/bin/skills/diffdock/SKILL.md +483 -0
  135. package/bin/skills/diffdock/assets/batch_template.csv +4 -0
  136. package/bin/skills/diffdock/assets/custom_inference_config.yaml +90 -0
  137. package/bin/skills/diffdock/references/confidence_and_limitations.md +182 -0
  138. package/bin/skills/diffdock/references/parameters_reference.md +163 -0
  139. package/bin/skills/diffdock/references/workflows_examples.md +392 -0
  140. package/bin/skills/diffdock/scripts/analyze_results.py +334 -0
  141. package/bin/skills/diffdock/scripts/prepare_batch_csv.py +254 -0
  142. package/bin/skills/diffdock/scripts/setup_check.py +278 -0
  143. package/bin/skills/dnanexus-integration/SKILL.md +383 -0
  144. package/bin/skills/dnanexus-integration/references/app-development.md +247 -0
  145. package/bin/skills/dnanexus-integration/references/configuration.md +646 -0
  146. package/bin/skills/dnanexus-integration/references/data-operations.md +400 -0
  147. package/bin/skills/dnanexus-integration/references/job-execution.md +412 -0
  148. package/bin/skills/dnanexus-integration/references/python-sdk.md +523 -0
  149. package/bin/skills/document-skills/docx/LICENSE.txt +30 -0
  150. package/bin/skills/document-skills/docx/SKILL.md +233 -0
  151. package/bin/skills/document-skills/docx/docx-js.md +350 -0
  152. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/dml-chart.xsd +1499 -0
  153. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/dml-chartDrawing.xsd +146 -0
  154. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/dml-diagram.xsd +1085 -0
  155. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/dml-lockedCanvas.xsd +11 -0
  156. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/dml-main.xsd +3081 -0
  157. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/dml-picture.xsd +23 -0
  158. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/dml-spreadsheetDrawing.xsd +185 -0
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  160. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/pml.xsd +1676 -0
  161. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/shared-additionalCharacteristics.xsd +28 -0
  162. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/shared-bibliography.xsd +144 -0
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  193. package/bin/skills/document-skills/docx/ooxml/scripts/validate.py +69 -0
  194. package/bin/skills/document-skills/docx/ooxml/scripts/validation/__init__.py +15 -0
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@@ -0,0 +1,412 @@
1
+ # File Manager API
2
+
3
+ ## Overview
4
+
5
+ The File Manager API enables file operations within protocols.io workspaces, including uploading files, organizing folders, searching content, and managing file lifecycle. This is useful for attaching data files, images, documents, and other resources to protocols.
6
+
7
+ ## Base URL
8
+
9
+ All file manager endpoints use the base URL: `https://protocols.io/api/v3`
10
+
11
+ ## Search and Browse
12
+
13
+ ### Search Workspace Files
14
+
15
+ Search for files and folders within a workspace.
16
+
17
+ **Endpoint:** `GET /workspaces/{workspace_id}/files/search`
18
+
19
+ **Path Parameters:**
20
+ - `workspace_id`: The workspace's unique identifier
21
+
22
+ **Query Parameters:**
23
+ - `query`: Search keywords (searches filenames and metadata)
24
+ - `type`: Filter by type
25
+ - `file`: Files only
26
+ - `folder`: Folders only
27
+ - `all`: Both files and folders (default)
28
+ - `folder_id`: Limit search to specific folder
29
+ - `page_size`: Number of results per page (default: 20, max: 100)
30
+ - `page_id`: Page number for pagination (starts at 0)
31
+
32
+ **Response includes:**
33
+ - File/folder ID and name
34
+ - File size and type
35
+ - Creation and modification dates
36
+ - File path in workspace
37
+ - Download URL (for files)
38
+
39
+ **Example Request:**
40
+ ```bash
41
+ curl -H "Authorization: Bearer YOUR_TOKEN" \
42
+ "https://protocols.io/api/v3/workspaces/12345/files/search?query=microscopy&type=file"
43
+ ```
44
+
45
+ ### List Folder Contents
46
+
47
+ Browse files and folders within a specific folder.
48
+
49
+ **Endpoint:** `GET /workspaces/{workspace_id}/folders/{folder_id}`
50
+
51
+ **Path Parameters:**
52
+ - `workspace_id`: The workspace's unique identifier
53
+ - `folder_id`: The folder's unique identifier (use `root` for workspace root)
54
+
55
+ **Query Parameters:**
56
+ - `order_by`: Sort field (`name`, `size`, `created`, `modified`)
57
+ - `order_dir`: Sort direction (`asc`, `desc`)
58
+ - `page_size`: Number of results per page
59
+ - `page_id`: Page number for pagination
60
+
61
+ **Example Request:**
62
+ ```bash
63
+ curl -H "Authorization: Bearer YOUR_TOKEN" \
64
+ "https://protocols.io/api/v3/workspaces/12345/folders/root?order_by=modified&order_dir=desc"
65
+ ```
66
+
67
+ ## File Upload
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+
69
+ ### Upload File
70
+
71
+ Upload a file to a workspace folder.
72
+
73
+ **Endpoint:** `POST /workspaces/{workspace_id}/files/upload`
74
+
75
+ **Request Format**: `multipart/form-data`
76
+
77
+ **Form Parameters:**
78
+ - `file` (required): The file to upload
79
+ - `folder_id`: Target folder ID (omit or use `root` for workspace root)
80
+ - `name`: Custom filename (optional, uses original filename if omitted)
81
+ - `description`: File description
82
+ - `tags`: Comma-separated tags
83
+
84
+ **Example Request:**
85
+ ```bash
86
+ curl -X POST \
87
+ -H "Authorization: Bearer YOUR_TOKEN" \
88
+ -F "file=@/path/to/local/data.xlsx" \
89
+ -F "folder_id=67890" \
90
+ -F "description=Experimental results from trial #3" \
91
+ -F "tags=experiment,data,2025" \
92
+ "https://protocols.io/api/v3/workspaces/12345/files/upload"
93
+ ```
94
+
95
+ ### Upload Verification
96
+
97
+ After upload, verify the file was processed correctly.
98
+
99
+ **Endpoint:** `GET /workspaces/{workspace_id}/files/{file_id}/status`
100
+
101
+ **Response includes:**
102
+ - Upload status (`processing`, `complete`, `failed`)
103
+ - File metadata
104
+ - Any processing errors
105
+
106
+ ## File Operations
107
+
108
+ ### Download File
109
+
110
+ Download a file from the workspace.
111
+
112
+ **Endpoint:** `GET /workspaces/{workspace_id}/files/{file_id}/download`
113
+
114
+ **Path Parameters:**
115
+ - `workspace_id`: The workspace's unique identifier
116
+ - `file_id`: The file's unique identifier
117
+
118
+ **Response**: Binary file data with appropriate Content-Type header
119
+
120
+ **Example Request:**
121
+ ```bash
122
+ curl -H "Authorization: Bearer YOUR_TOKEN" \
123
+ -o "downloaded_file.xlsx" \
124
+ "https://protocols.io/api/v3/workspaces/12345/files/67890/download"
125
+ ```
126
+
127
+ ### Get File Metadata
128
+
129
+ Retrieve file information without downloading.
130
+
131
+ **Endpoint:** `GET /workspaces/{workspace_id}/files/{file_id}`
132
+
133
+ **Response includes:**
134
+ - File name, size, and type
135
+ - Upload date and author
136
+ - Description and tags
137
+ - File path and location
138
+ - Download URL
139
+ - Sharing permissions
140
+
141
+ ### Update File Metadata
142
+
143
+ Update file description, tags, or other metadata.
144
+
145
+ **Endpoint:** `PATCH /workspaces/{workspace_id}/files/{file_id}`
146
+
147
+ **Request Body:**
148
+ - `name`: New filename
149
+ - `description`: Updated description
150
+ - `tags`: Updated tags (comma-separated)
151
+ - `folder_id`: Move to different folder
152
+
153
+ **Example Request:**
154
+ ```bash
155
+ curl -X PATCH \
156
+ -H "Authorization: Bearer YOUR_TOKEN" \
157
+ -H "Content-Type: application/json" \
158
+ -d '{
159
+ "description": "Experimental results from trial #3 - REVISED",
160
+ "tags": "experiment,data,2025,revised"
161
+ }' \
162
+ "https://protocols.io/api/v3/workspaces/12345/files/67890"
163
+ ```
164
+
165
+ ### Delete File
166
+
167
+ Move a file to trash (soft delete).
168
+
169
+ **Endpoint:** `DELETE /workspaces/{workspace_id}/files/{file_id}`
170
+
171
+ **Note**: Deleted files may be recoverable from trash for a limited time
172
+
173
+ ### Restore File
174
+
175
+ Restore a deleted file from trash.
176
+
177
+ **Endpoint:** `POST /workspaces/{workspace_id}/files/{file_id}/restore`
178
+
179
+ ## Folder Operations
180
+
181
+ ### Create Folder
182
+
183
+ Create a new folder in the workspace.
184
+
185
+ **Endpoint:** `POST /workspaces/{workspace_id}/folders`
186
+
187
+ **Request Body:**
188
+ - `name` (required): Folder name
189
+ - `parent_folder_id`: Parent folder ID (omit for workspace root)
190
+ - `description`: Folder description
191
+
192
+ **Example Request:**
193
+ ```bash
194
+ curl -X POST \
195
+ -H "Authorization: Bearer YOUR_TOKEN" \
196
+ -H "Content-Type: application/json" \
197
+ -d '{
198
+ "name": "2025 Experiments",
199
+ "parent_folder_id": "root",
200
+ "description": "All experimental data from 2025"
201
+ }' \
202
+ "https://protocols.io/api/v3/workspaces/12345/folders"
203
+ ```
204
+
205
+ ### Rename Folder
206
+
207
+ **Endpoint:** `PATCH /workspaces/{workspace_id}/folders/{folder_id}`
208
+
209
+ **Request Body:**
210
+ - `name`: New folder name
211
+ - `description`: Updated description
212
+
213
+ ### Delete Folder
214
+
215
+ Delete a folder and optionally its contents.
216
+
217
+ **Endpoint:** `DELETE /workspaces/{workspace_id}/folders/{folder_id}`
218
+
219
+ **Query Parameters:**
220
+ - `recursive`: Set to `true` to delete folder and all contents (default: `false`)
221
+
222
+ **Warning**: Recursive deletion cannot be easily undone
223
+
224
+ ## Common Use Cases
225
+
226
+ ### 1. Protocol Data Attachment
227
+
228
+ Attach experimental data files to protocols:
229
+
230
+ 1. Upload data files: `POST /workspaces/{id}/files/upload`
231
+ 2. Verify upload completion
232
+ 3. Reference file IDs in protocol steps
233
+ 4. Include download links in protocol description
234
+
235
+ **Example Workflow:**
236
+ ```bash
237
+ # Upload the data file
238
+ curl -X POST \
239
+ -H "Authorization: Bearer YOUR_TOKEN" \
240
+ -F "file=@results.csv" \
241
+ -F "description=Results from protocol execution" \
242
+ "https://protocols.io/api/v3/workspaces/12345/files/upload"
243
+
244
+ # Note the file_id from response, then reference in protocol
245
+ ```
246
+
247
+ ### 2. Workspace Organization
248
+
249
+ Organize files into logical folder structures:
250
+
251
+ 1. Create folder hierarchy: `POST /workspaces/{id}/folders`
252
+ 2. Upload files to appropriate folders
253
+ 3. Use consistent naming conventions
254
+ 4. Tag files for easy search
255
+
256
+ **Example Structure:**
257
+ ```
258
+ Workspace Root
259
+ ├── Protocols
260
+ │ ├── Published
261
+ │ └── Drafts
262
+ ├── Data
263
+ │ ├── Raw
264
+ │ └── Processed
265
+ ├── Images
266
+ │ ├── Microscopy
267
+ │ └── Gels
268
+ └── Documents
269
+ ├── Papers
270
+ └── Presentations
271
+ ```
272
+
273
+ ### 3. File Search and Discovery
274
+
275
+ Find files across workspace:
276
+
277
+ 1. Search by keywords: `GET /workspaces/{id}/files/search?query=keywords`
278
+ 2. Filter by type and date
279
+ 3. Download relevant files
280
+ 4. Update metadata for better organization
281
+
282
+ ### 4. Batch File Upload
283
+
284
+ Upload multiple related files:
285
+
286
+ 1. Create target folder
287
+ 2. For each file:
288
+ - Upload file
289
+ - Verify upload status
290
+ - Add consistent tags
291
+ 3. Create index or manifest file listing all uploads
292
+
293
+ ### 5. Data Backup and Export
294
+
295
+ Export workspace files for backup:
296
+
297
+ 1. List all folders: `GET /workspaces/{id}/folders/root`
298
+ 2. For each folder, list files
299
+ 3. Download all files: `GET /workspaces/{id}/files/{file_id}/download`
300
+ 4. Maintain folder structure locally
301
+ 5. Store metadata separately for restoration
302
+
303
+ ### 6. File Versioning
304
+
305
+ Manage file versions manually:
306
+
307
+ 1. Upload new version with versioned name (e.g., `data_v2.csv`)
308
+ 2. Update previous version metadata to indicate superseded
309
+ 3. Maintain version history in folder structure
310
+ 4. Reference specific versions in protocols
311
+
312
+ ## Supported File Types
313
+
314
+ Protocols.io supports various file types:
315
+
316
+ **Data Files:**
317
+ - Spreadsheets: `.xlsx`, `.xls`, `.csv`, `.tsv`
318
+ - Statistical data: `.rds`, `.rdata`, `.sav`, `.dta`
319
+ - Plain text: `.txt`, `.log`, `.json`, `.xml`
320
+
321
+ **Images:**
322
+ - Common formats: `.jpg`, `.jpeg`, `.png`, `.gif`, `.bmp`, `.tif`, `.tiff`
323
+ - Scientific: `.czi`, `.nd2`, `.lsm` (may require special handling)
324
+
325
+ **Documents:**
326
+ - PDF: `.pdf`
327
+ - Word: `.docx`, `.doc`
328
+ - PowerPoint: `.pptx`, `.ppt`
329
+
330
+ **Code and Scripts:**
331
+ - Python: `.py`, `.ipynb`
332
+ - R: `.r`, `.rmd`
333
+ - Shell: `.sh`, `.bash`
334
+
335
+ **Multimedia:**
336
+ - Video: `.mp4`, `.avi`, `.mov`
337
+ - Audio: `.mp3`, `.wav`
338
+
339
+ **Archives:**
340
+ - Compressed: `.zip`, `.tar.gz`, `.7z`
341
+
342
+ **File Size Limits:**
343
+ - Standard files: Check workspace limits (typically 100 MB - 1 GB)
344
+ - Large files: May require chunked upload or special handling
345
+
346
+ ## Best Practices
347
+
348
+ 1. **File Naming**
349
+ - Use descriptive, consistent naming conventions
350
+ - Include dates in ISO format (YYYY-MM-DD)
351
+ - Avoid special characters and spaces (use underscores)
352
+ - Example: `experiment_results_2025-10-26.csv`
353
+
354
+ 2. **Organization**
355
+ - Create logical folder hierarchy
356
+ - Group related files together
357
+ - Separate raw data from processed results
358
+ - Keep protocol-specific files in dedicated folders
359
+
360
+ 3. **Metadata**
361
+ - Add detailed descriptions
362
+ - Tag files consistently
363
+ - Include version information
364
+ - Document processing steps
365
+
366
+ 4. **Storage Management**
367
+ - Regularly review and archive old files
368
+ - Delete unnecessary duplicates
369
+ - Compress large datasets
370
+ - Monitor workspace storage limits
371
+
372
+ 5. **Collaboration**
373
+ - Use clear file names for team members
374
+ - Document file purposes in descriptions
375
+ - Maintain consistent folder structures
376
+ - Communicate major organizational changes
377
+
378
+ 6. **Security**
379
+ - Avoid uploading sensitive data without proper permissions
380
+ - Be aware of workspace visibility settings
381
+ - Use appropriate access controls
382
+ - Regularly audit file access
383
+
384
+ ## Error Handling
385
+
386
+ Common error responses:
387
+
388
+ - `400 Bad Request`: Invalid file format or parameters
389
+ - `401 Unauthorized`: Missing or invalid access token
390
+ - `403 Forbidden`: Insufficient workspace permissions
391
+ - `404 Not Found`: File or folder not found
392
+ - `413 Payload Too Large`: File exceeds size limit
393
+ - `422 Unprocessable Entity`: File validation failed
394
+ - `429 Too Many Requests`: Rate limit exceeded
395
+ - `507 Insufficient Storage`: Workspace storage limit reached
396
+
397
+ ## Performance Considerations
398
+
399
+ 1. **Large Files**
400
+ - Consider chunked upload for files > 100 MB
401
+ - Use compression for large datasets
402
+ - Upload during off-peak hours if possible
403
+
404
+ 2. **Batch Operations**
405
+ - Implement retry logic for failed uploads
406
+ - Use exponential backoff for rate limits
407
+ - Process uploads in parallel where possible
408
+
409
+ 3. **Download Optimization**
410
+ - Cache frequently accessed files locally
411
+ - Use streaming for large file downloads
412
+ - Implement resume capability for interrupted downloads
@@ -0,0 +1,294 @@
1
+ # Protocols API
2
+
3
+ ## Overview
4
+
5
+ The Protocols API is the core functionality of protocols.io, supporting the complete protocol lifecycle from creation to publication. This includes searching, creating, updating, managing steps, handling materials, bookmarking, and generating PDFs.
6
+
7
+ ## Base URL
8
+
9
+ All protocol endpoints use the base URL: `https://protocols.io/api/v3`
10
+
11
+ ## Content Format Parameter
12
+
13
+ Many endpoints support a `content_format` parameter to specify how content is returned:
14
+
15
+ - `json`: Draft.js JSON format (default)
16
+ - `html`: HTML format
17
+ - `markdown`: Markdown format
18
+
19
+ Include this as a query parameter: `?content_format=html`
20
+
21
+ ## List and Search Operations
22
+
23
+ ### List Protocols
24
+
25
+ Retrieve protocols with filtering and pagination.
26
+
27
+ **Endpoint:** `GET /protocols`
28
+
29
+ **Query Parameters:**
30
+ - `filter`: Filter type
31
+ - `public`: Public protocols only
32
+ - `private`: Your private protocols
33
+ - `shared`: Protocols shared with you
34
+ - `user_public`: Another user's public protocols
35
+ - `key`: Search keywords in protocol title, description, and content
36
+ - `order_field`: Sort field (`activity`, `created_on`, `modified_on`, `name`, `id`)
37
+ - `order_dir`: Sort direction (`desc`, `asc`)
38
+ - `page_size`: Number of results per page (default: 10, max: 50)
39
+ - `page_id`: Page number for pagination (starts at 0)
40
+ - `fields`: Comma-separated list of fields to return
41
+ - `content_format`: Content format (`json`, `html`, `markdown`)
42
+
43
+ **Example Request:**
44
+ ```bash
45
+ curl -H "Authorization: Bearer YOUR_TOKEN" \
46
+ "https://protocols.io/api/v3/protocols?filter=public&key=CRISPR&page_size=20&content_format=html"
47
+ ```
48
+
49
+ ### Search by DOI
50
+
51
+ Retrieve a protocol by its DOI.
52
+
53
+ **Endpoint:** `GET /protocols/{doi}`
54
+
55
+ **Path Parameters:**
56
+ - `doi`: The protocol DOI (e.g., `dx.doi.org/10.17504/protocols.io.xxxxx`)
57
+
58
+ ## Retrieve Protocol Details
59
+
60
+ ### Get Protocol by ID
61
+
62
+ **Endpoint:** `GET /protocols/{protocol_id}`
63
+
64
+ **Path Parameters:**
65
+ - `protocol_id`: The protocol's unique identifier
66
+
67
+ **Query Parameters:**
68
+ - `content_format`: Content format (`json`, `html`, `markdown`)
69
+
70
+ **Response includes:**
71
+ - Protocol metadata (title, authors, description, DOI)
72
+ - All protocol steps with content
73
+ - Materials and reagents
74
+ - Guidelines and warnings
75
+ - Version information
76
+ - Publication status
77
+
78
+ ## Create and Update Protocols
79
+
80
+ ### Create New Protocol
81
+
82
+ **Endpoint:** `POST /protocols`
83
+
84
+ **Request Body Parameters:**
85
+ - `title` (required): Protocol title
86
+ - `description`: Protocol description
87
+ - `tags`: Array of tag strings
88
+ - `vendor_name`: Vendor/company name
89
+ - `vendor_link`: Vendor website URL
90
+ - `warning`: Warning or safety message
91
+ - `guidelines`: Usage guidelines
92
+ - `manuscript_citation`: Citation for related manuscript
93
+ - `link`: External link to related resource
94
+
95
+ **Example Request:**
96
+ ```bash
97
+ curl -X POST \
98
+ -H "Authorization: Bearer YOUR_TOKEN" \
99
+ -H "Content-Type: application/json" \
100
+ -d '{
101
+ "title": "CRISPR Gene Editing Protocol",
102
+ "description": "Comprehensive protocol for CRISPR-Cas9 mediated gene editing",
103
+ "tags": ["CRISPR", "gene editing", "molecular biology"]
104
+ }' \
105
+ "https://protocols.io/api/v3/protocols"
106
+ ```
107
+
108
+ ### Update Protocol
109
+
110
+ **Endpoint:** `PATCH /protocols/{protocol_id}`
111
+
112
+ **Path Parameters:**
113
+ - `protocol_id`: The protocol's unique identifier
114
+
115
+ **Request Body**: Same parameters as create, all optional
116
+
117
+ ## Protocol Steps Management
118
+
119
+ ### Create Protocol Step
120
+
121
+ **Endpoint:** `POST /protocols/{protocol_id}/steps`
122
+
123
+ **Request Body Parameters:**
124
+ - `title` (required): Step title
125
+ - `description`: Step description (HTML, Markdown, or Draft.js JSON)
126
+ - `duration`: Step duration in seconds
127
+ - `temperature`: Temperature setting
128
+ - `components`: Array of materials/reagents used
129
+ - `software`: Software or tools required
130
+ - `commands`: Commands to execute
131
+ - `expected_result`: Expected outcome description
132
+
133
+ **Example Request:**
134
+ ```bash
135
+ curl -X POST \
136
+ -H "Authorization: Bearer YOUR_TOKEN" \
137
+ -H "Content-Type: application/json" \
138
+ -d '{
139
+ "title": "Prepare sgRNA",
140
+ "description": "Design and synthesize single guide RNA (sgRNA) targeting your gene of interest",
141
+ "duration": 3600,
142
+ "temperature": 25
143
+ }' \
144
+ "https://protocols.io/api/v3/protocols/12345/steps"
145
+ ```
146
+
147
+ ### Update Protocol Step
148
+
149
+ **Endpoint:** `PATCH /protocols/{protocol_id}/steps/{step_id}`
150
+
151
+ **Parameters**: Same as create step, all optional
152
+
153
+ ### Delete Protocol Step
154
+
155
+ **Endpoint:** `DELETE /protocols/{protocol_id}/steps/{step_id}`
156
+
157
+ ### Reorder Steps
158
+
159
+ **Endpoint:** `POST /protocols/{protocol_id}/steps/reorder`
160
+
161
+ **Request Body:**
162
+ - `step_order`: Array of step IDs in desired order
163
+
164
+ ## Materials and Reagents
165
+
166
+ ### Get Protocol Materials
167
+
168
+ Retrieve all materials and reagents used in a protocol.
169
+
170
+ **Endpoint:** `GET /protocols/{protocol_id}/materials`
171
+
172
+ **Response includes:**
173
+ - Reagent names and descriptions
174
+ - Catalog numbers
175
+ - Vendor information
176
+ - Concentrations and amounts
177
+ - Links to product pages
178
+
179
+ ## Publishing and DOI
180
+
181
+ ### Publish Protocol
182
+
183
+ Issue a DOI and make the protocol publicly available.
184
+
185
+ **Endpoint:** `POST /protocols/{protocol_id}/publish`
186
+
187
+ **Request Body Parameters:**
188
+ - `version_notes`: Description of changes in this version
189
+ - `publish_type`: Publication type
190
+ - `new`: First publication
191
+ - `update`: Update to existing published protocol
192
+
193
+ **Important Notes:**
194
+ - Once published, protocols receive a permanent DOI
195
+ - Published protocols cannot be deleted, only updated with new versions
196
+ - Published protocols are publicly accessible
197
+
198
+ **Example Request:**
199
+ ```bash
200
+ curl -X POST \
201
+ -H "Authorization: Bearer YOUR_TOKEN" \
202
+ -H "Content-Type: application/json" \
203
+ -d '{
204
+ "version_notes": "Initial publication",
205
+ "publish_type": "new"
206
+ }' \
207
+ "https://protocols.io/api/v3/protocols/12345/publish"
208
+ ```
209
+
210
+ ## Bookmarks
211
+
212
+ ### Add Bookmark
213
+
214
+ Add a protocol to your bookmarks for quick access.
215
+
216
+ **Endpoint:** `POST /protocols/{protocol_id}/bookmarks`
217
+
218
+ ### Remove Bookmark
219
+
220
+ **Endpoint:** `DELETE /protocols/{protocol_id}/bookmarks`
221
+
222
+ ### List Bookmarked Protocols
223
+
224
+ **Endpoint:** `GET /bookmarks`
225
+
226
+ ## PDF Export
227
+
228
+ ### Generate Protocol PDF
229
+
230
+ Generate a formatted PDF version of a protocol.
231
+
232
+ **Endpoint:** `GET /view/{protocol_uri}.pdf`
233
+
234
+ **Query Parameters:**
235
+ - `compact`: Set to `1` for compact view without large spacing
236
+
237
+ **Rate Limits:**
238
+ - Signed-in users: 5 requests per minute
239
+ - Unsigned users: 3 requests per minute
240
+
241
+ **Example:**
242
+ ```
243
+ https://protocols.io/api/v3/view/crispr-protocol-abc123.pdf?compact=1
244
+ ```
245
+
246
+ ## Common Use Cases
247
+
248
+ ### 1. Import Existing Protocol
249
+
250
+ To import and work with an existing protocol:
251
+
252
+ 1. Search for the protocol using keywords or DOI
253
+ 2. Retrieve full protocol details with `/protocols/{protocol_id}`
254
+ 3. Extract steps, materials, and metadata for local use
255
+
256
+ ### 2. Create New Protocol from Scratch
257
+
258
+ To create a new protocol:
259
+
260
+ 1. Create protocol with title and description: `POST /protocols`
261
+ 2. Add steps sequentially: `POST /protocols/{id}/steps`
262
+ 3. Review and test the protocol
263
+ 4. Publish when ready: `POST /protocols/{id}/publish`
264
+
265
+ ### 3. Update Published Protocol
266
+
267
+ To update an already-published protocol:
268
+
269
+ 1. Retrieve current version: `GET /protocols/{protocol_id}`
270
+ 2. Make necessary updates: `PATCH /protocols/{protocol_id}`
271
+ 3. Update or add steps as needed
272
+ 4. Publish new version: `POST /protocols/{protocol_id}/publish` with `publish_type: "update"`
273
+
274
+ ### 4. Clone and Modify Protocol
275
+
276
+ To create a modified version of an existing protocol:
277
+
278
+ 1. Retrieve original protocol details
279
+ 2. Create new protocol with modified metadata
280
+ 3. Copy and modify steps from original
281
+ 4. Publish as new protocol
282
+
283
+ ## Error Handling
284
+
285
+ Common error responses:
286
+
287
+ - `400 Bad Request`: Invalid parameters or request format
288
+ - `401 Unauthorized`: Missing or invalid access token
289
+ - `403 Forbidden`: Insufficient permissions for the operation
290
+ - `404 Not Found`: Protocol or resource not found
291
+ - `429 Too Many Requests`: Rate limit exceeded
292
+ - `500 Internal Server Error`: Server-side error
293
+
294
+ Implement retry logic with exponential backoff for `429` and `500` errors.