@synsci/cli-darwin-x64-baseline 1.1.76 → 1.1.78

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (830) hide show
  1. package/bin/skills/adaptyv/SKILL.md +114 -0
  2. package/bin/skills/adaptyv/reference/api_reference.md +308 -0
  3. package/bin/skills/adaptyv/reference/examples.md +913 -0
  4. package/bin/skills/adaptyv/reference/experiments.md +360 -0
  5. package/bin/skills/adaptyv/reference/protein_optimization.md +637 -0
  6. package/bin/skills/aeon/SKILL.md +374 -0
  7. package/bin/skills/aeon/references/anomaly_detection.md +154 -0
  8. package/bin/skills/aeon/references/classification.md +144 -0
  9. package/bin/skills/aeon/references/clustering.md +123 -0
  10. package/bin/skills/aeon/references/datasets_benchmarking.md +387 -0
  11. package/bin/skills/aeon/references/distances.md +256 -0
  12. package/bin/skills/aeon/references/forecasting.md +140 -0
  13. package/bin/skills/aeon/references/networks.md +289 -0
  14. package/bin/skills/aeon/references/regression.md +118 -0
  15. package/bin/skills/aeon/references/segmentation.md +163 -0
  16. package/bin/skills/aeon/references/similarity_search.md +187 -0
  17. package/bin/skills/aeon/references/transformations.md +246 -0
  18. package/bin/skills/alphafold-database/SKILL.md +513 -0
  19. package/bin/skills/alphafold-database/references/api_reference.md +423 -0
  20. package/bin/skills/anndata/SKILL.md +400 -0
  21. package/bin/skills/anndata/references/best_practices.md +525 -0
  22. package/bin/skills/anndata/references/concatenation.md +396 -0
  23. package/bin/skills/anndata/references/data_structure.md +314 -0
  24. package/bin/skills/anndata/references/io_operations.md +404 -0
  25. package/bin/skills/anndata/references/manipulation.md +516 -0
  26. package/bin/skills/arboreto/SKILL.md +243 -0
  27. package/bin/skills/arboreto/references/algorithms.md +138 -0
  28. package/bin/skills/arboreto/references/basic_inference.md +151 -0
  29. package/bin/skills/arboreto/references/distributed_computing.md +242 -0
  30. package/bin/skills/arboreto/scripts/basic_grn_inference.py +97 -0
  31. package/bin/skills/astropy/SKILL.md +331 -0
  32. package/bin/skills/astropy/references/coordinates.md +273 -0
  33. package/bin/skills/astropy/references/cosmology.md +307 -0
  34. package/bin/skills/astropy/references/fits.md +396 -0
  35. package/bin/skills/astropy/references/tables.md +489 -0
  36. package/bin/skills/astropy/references/time.md +404 -0
  37. package/bin/skills/astropy/references/units.md +178 -0
  38. package/bin/skills/astropy/references/wcs_and_other_modules.md +373 -0
  39. package/bin/skills/benchling-integration/SKILL.md +480 -0
  40. package/bin/skills/benchling-integration/references/api_endpoints.md +883 -0
  41. package/bin/skills/benchling-integration/references/authentication.md +379 -0
  42. package/bin/skills/benchling-integration/references/sdk_reference.md +774 -0
  43. package/bin/skills/biopython/SKILL.md +443 -0
  44. package/bin/skills/biopython/references/advanced.md +577 -0
  45. package/bin/skills/biopython/references/alignment.md +362 -0
  46. package/bin/skills/biopython/references/blast.md +455 -0
  47. package/bin/skills/biopython/references/databases.md +484 -0
  48. package/bin/skills/biopython/references/phylogenetics.md +566 -0
  49. package/bin/skills/biopython/references/sequence_io.md +285 -0
  50. package/bin/skills/biopython/references/structure.md +564 -0
  51. package/bin/skills/biorxiv-database/SKILL.md +483 -0
  52. package/bin/skills/biorxiv-database/references/api_reference.md +280 -0
  53. package/bin/skills/biorxiv-database/scripts/biorxiv_search.py +445 -0
  54. package/bin/skills/bioservices/SKILL.md +361 -0
  55. package/bin/skills/bioservices/references/identifier_mapping.md +685 -0
  56. package/bin/skills/bioservices/references/services_reference.md +636 -0
  57. package/bin/skills/bioservices/references/workflow_patterns.md +811 -0
  58. package/bin/skills/bioservices/scripts/batch_id_converter.py +347 -0
  59. package/bin/skills/bioservices/scripts/compound_cross_reference.py +378 -0
  60. package/bin/skills/bioservices/scripts/pathway_analysis.py +309 -0
  61. package/bin/skills/bioservices/scripts/protein_analysis_workflow.py +408 -0
  62. package/bin/skills/brenda-database/SKILL.md +719 -0
  63. package/bin/skills/brenda-database/references/api_reference.md +537 -0
  64. package/bin/skills/brenda-database/scripts/brenda_queries.py +844 -0
  65. package/bin/skills/brenda-database/scripts/brenda_visualization.py +772 -0
  66. package/bin/skills/brenda-database/scripts/enzyme_pathway_builder.py +1053 -0
  67. package/bin/skills/cellxgene-census/SKILL.md +511 -0
  68. package/bin/skills/cellxgene-census/references/census_schema.md +182 -0
  69. package/bin/skills/cellxgene-census/references/common_patterns.md +351 -0
  70. package/bin/skills/chembl-database/SKILL.md +389 -0
  71. package/bin/skills/chembl-database/references/api_reference.md +272 -0
  72. package/bin/skills/chembl-database/scripts/example_queries.py +278 -0
  73. package/bin/skills/cirq/SKILL.md +346 -0
  74. package/bin/skills/cirq/references/building.md +307 -0
  75. package/bin/skills/cirq/references/experiments.md +572 -0
  76. package/bin/skills/cirq/references/hardware.md +515 -0
  77. package/bin/skills/cirq/references/noise.md +515 -0
  78. package/bin/skills/cirq/references/simulation.md +350 -0
  79. package/bin/skills/cirq/references/transformation.md +416 -0
  80. package/bin/skills/clinicaltrials-database/SKILL.md +507 -0
  81. package/bin/skills/clinicaltrials-database/references/api_reference.md +358 -0
  82. package/bin/skills/clinicaltrials-database/scripts/query_clinicaltrials.py +215 -0
  83. package/bin/skills/clinpgx-database/SKILL.md +638 -0
  84. package/bin/skills/clinpgx-database/references/api_reference.md +757 -0
  85. package/bin/skills/clinpgx-database/scripts/query_clinpgx.py +518 -0
  86. package/bin/skills/clinvar-database/SKILL.md +362 -0
  87. package/bin/skills/clinvar-database/references/api_reference.md +227 -0
  88. package/bin/skills/clinvar-database/references/clinical_significance.md +218 -0
  89. package/bin/skills/clinvar-database/references/data_formats.md +358 -0
  90. package/bin/skills/cobrapy/SKILL.md +463 -0
  91. package/bin/skills/cobrapy/references/api_quick_reference.md +655 -0
  92. package/bin/skills/cobrapy/references/workflows.md +593 -0
  93. package/bin/skills/cosmic-database/SKILL.md +336 -0
  94. package/bin/skills/cosmic-database/references/cosmic_data_reference.md +220 -0
  95. package/bin/skills/cosmic-database/scripts/download_cosmic.py +231 -0
  96. package/bin/skills/dask/SKILL.md +456 -0
  97. package/bin/skills/dask/references/arrays.md +497 -0
  98. package/bin/skills/dask/references/bags.md +468 -0
  99. package/bin/skills/dask/references/best-practices.md +277 -0
  100. package/bin/skills/dask/references/dataframes.md +368 -0
  101. package/bin/skills/dask/references/futures.md +541 -0
  102. package/bin/skills/dask/references/schedulers.md +504 -0
  103. package/bin/skills/datacommons-client/SKILL.md +255 -0
  104. package/bin/skills/datacommons-client/references/getting_started.md +417 -0
  105. package/bin/skills/datacommons-client/references/node.md +250 -0
  106. package/bin/skills/datacommons-client/references/observation.md +185 -0
  107. package/bin/skills/datacommons-client/references/resolve.md +246 -0
  108. package/bin/skills/datamol/SKILL.md +706 -0
  109. package/bin/skills/datamol/references/conformers_module.md +131 -0
  110. package/bin/skills/datamol/references/core_api.md +130 -0
  111. package/bin/skills/datamol/references/descriptors_viz.md +195 -0
  112. package/bin/skills/datamol/references/fragments_scaffolds.md +174 -0
  113. package/bin/skills/datamol/references/io_module.md +109 -0
  114. package/bin/skills/datamol/references/reactions_data.md +218 -0
  115. package/bin/skills/deepchem/SKILL.md +597 -0
  116. package/bin/skills/deepchem/references/api_reference.md +303 -0
  117. package/bin/skills/deepchem/references/workflows.md +491 -0
  118. package/bin/skills/deepchem/scripts/graph_neural_network.py +338 -0
  119. package/bin/skills/deepchem/scripts/predict_solubility.py +224 -0
  120. package/bin/skills/deepchem/scripts/transfer_learning.py +375 -0
  121. package/bin/skills/deeptools/SKILL.md +531 -0
  122. package/bin/skills/deeptools/assets/quick_reference.md +58 -0
  123. package/bin/skills/deeptools/references/effective_genome_sizes.md +116 -0
  124. package/bin/skills/deeptools/references/normalization_methods.md +410 -0
  125. package/bin/skills/deeptools/references/tools_reference.md +533 -0
  126. package/bin/skills/deeptools/references/workflows.md +474 -0
  127. package/bin/skills/deeptools/scripts/validate_files.py +195 -0
  128. package/bin/skills/deeptools/scripts/workflow_generator.py +454 -0
  129. package/bin/skills/denario/SKILL.md +215 -0
  130. package/bin/skills/denario/references/examples.md +494 -0
  131. package/bin/skills/denario/references/installation.md +213 -0
  132. package/bin/skills/denario/references/llm_configuration.md +265 -0
  133. package/bin/skills/denario/references/research_pipeline.md +471 -0
  134. package/bin/skills/diffdock/SKILL.md +483 -0
  135. package/bin/skills/diffdock/assets/batch_template.csv +4 -0
  136. package/bin/skills/diffdock/assets/custom_inference_config.yaml +90 -0
  137. package/bin/skills/diffdock/references/confidence_and_limitations.md +182 -0
  138. package/bin/skills/diffdock/references/parameters_reference.md +163 -0
  139. package/bin/skills/diffdock/references/workflows_examples.md +392 -0
  140. package/bin/skills/diffdock/scripts/analyze_results.py +334 -0
  141. package/bin/skills/diffdock/scripts/prepare_batch_csv.py +254 -0
  142. package/bin/skills/diffdock/scripts/setup_check.py +278 -0
  143. package/bin/skills/dnanexus-integration/SKILL.md +383 -0
  144. package/bin/skills/dnanexus-integration/references/app-development.md +247 -0
  145. package/bin/skills/dnanexus-integration/references/configuration.md +646 -0
  146. package/bin/skills/dnanexus-integration/references/data-operations.md +400 -0
  147. package/bin/skills/dnanexus-integration/references/job-execution.md +412 -0
  148. package/bin/skills/dnanexus-integration/references/python-sdk.md +523 -0
  149. package/bin/skills/document-skills/docx/LICENSE.txt +30 -0
  150. package/bin/skills/document-skills/docx/SKILL.md +233 -0
  151. package/bin/skills/document-skills/docx/docx-js.md +350 -0
  152. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/dml-chart.xsd +1499 -0
  153. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/dml-chartDrawing.xsd +146 -0
  154. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/dml-diagram.xsd +1085 -0
  155. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/dml-lockedCanvas.xsd +11 -0
  156. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/dml-main.xsd +3081 -0
  157. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/dml-picture.xsd +23 -0
  158. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/dml-spreadsheetDrawing.xsd +185 -0
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  160. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/pml.xsd +1676 -0
  161. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/shared-additionalCharacteristics.xsd +28 -0
  162. package/bin/skills/document-skills/docx/ooxml/schemas/ISO-IEC29500-4_2016/shared-bibliography.xsd +144 -0
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  193. package/bin/skills/document-skills/docx/ooxml/scripts/validate.py +69 -0
  194. package/bin/skills/document-skills/docx/ooxml/scripts/validation/__init__.py +15 -0
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+ # DICOMweb Guide for IDC
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+
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+ IDC provides DICOMweb access through Google Cloud Healthcare API DICOM stores. This guide covers the implementation specifics and usage patterns.
4
+
5
+ ## When to Use DICOMweb
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+
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+ Use DICOMweb when you need:
8
+ - Integration with PACS systems or DICOMweb-compatible tools
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+ - Streaming metadata without downloading full files
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+ - Building custom viewers or web applications
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+ - Using existing DICOMweb client libraries (OHIF, dicomweb-client, etc.)
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+
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+ For most use cases, `idc-index` is simpler and recommended. Use DICOMweb when you specifically need the DICOMweb protocol.
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+
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+ ## Endpoints
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+
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+ ### Public Proxy (No Authentication)
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+
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+ ```
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+ https://proxy.imaging.datacommons.cancer.gov/current/viewer-only-no-downloads-see-tinyurl-dot-com-slash-3j3d9jyp/dicomWeb
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+ ```
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+
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+ - **100% data coverage** - Contains all IDC data from all storage buckets
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+ - Points to the latest IDC version automatically
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+ - **Updates immediately** on new IDC releases
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+ - Per-IP daily quota (suitable for testing and moderate use)
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+ - No authentication required
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+ - Read-only access
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+ - Note: "viewer-only-no-downloads" in URL is legacy naming with no functional meaning
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+
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+ ### Google Healthcare API (Requires Authentication)
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+
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+ ```
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+ https://healthcare.googleapis.com/v1/projects/nci-idc-data/locations/us-central1/datasets/idc/dicomStores/idc-store-v{VERSION}/dicomWeb
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+ ```
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+
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+ Replace `{VERSION}` with the IDC release number. To find the current version:
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+
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+ ```python
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+ from idc_index import IDCClient
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+ client = IDCClient()
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+ print(client.get_idc_version()) # e.g., "23" for v23
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+ ```
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+
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+ - **~96% data coverage** - Only replicates data from `idc-open-data` bucket (missing ~4% from other buckets)
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+ - **Updates 1-2 weeks after** IDC releases
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+ - Requires authentication and provides higher quotas
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+ - Better performance (no proxy routing)
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+ - Each release gets a new versioned store
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+
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+ See [Content Coverage Differences](#content-coverage-differences) and [Authentication](#authentication-for-google-healthcare-api) sections below.
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+
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+ ## Content Coverage Differences
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+
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+ **Important:** The two DICOMweb endpoints have different data coverage. The IDC public proxy contains MORE data than the authenticated Google Healthcare endpoint.
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+
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+ ### Coverage Summary
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+
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+ | Endpoint | Coverage | Missing Data |
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+ |----------|----------|--------------|
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+ | **IDC Public Proxy** | 100% | None |
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+ | **Google Healthcare API** | ~96% | ~4% (two buckets not replicated) |
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+
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+ ### What's Missing from Google Healthcare?
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+
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+ The Google Healthcare DICOM store **only replicates data from the `idc-open-data` S3 bucket**. It does not include data from two additional buckets:
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+
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+ - `idc-open-data-cr`
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+ - `idc-open-data-two`
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+
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+ These missing buckets typically contain several thousand series each, representing approximately 4% of total IDC data. The exact counts vary by IDC version.
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+
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+ See `cloud_storage_guide.md` for details on bucket organization, file structure, and direct access methods.
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+
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+ ### Update Timing
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+
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+ - **IDC Public Proxy**: Updates immediately when new IDC versions are released
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+ - **Google Healthcare**: Updates 1-2 weeks after each new IDC version release
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+
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+ Between releases, both endpoints remain current. The 1-2 week delay only occurs during the transition period after a new IDC version is published.
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+
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+ **Warning from IDC documentation:** *"Google-hosted DICOM store may not contain the latest version of IDC data!"* - Check during the weeks following a new release.
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+
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+ ### Choosing the Right Endpoint
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+
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+ **Use IDC Public Proxy when:**
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+ - You need complete data coverage (100%)
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+ - You need the absolute latest data immediately after a new version release
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+ - You don't want to set up GCP authentication
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+ - Your usage fits within per-IP quotas (can request increases via support@canceridc.dev)
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+ - You're accessing slide microscopy images frame-by-frame
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+
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+ **Use Google Healthcare API when:**
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+ - The ~4% missing data doesn't affect your use case
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+ - You need higher quotas for heavy usage
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+ - You want better performance (direct access, no proxy routing)
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+
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+ ### Checking Your Data Availability
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+
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+ Before choosing an endpoint, verify whether your data might be in the missing buckets:
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+
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+ ```python
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+ from idc_index import IDCClient
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+
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+ client = IDCClient()
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+
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+ # Check which buckets contain your collection's data
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+ results = client.sql_query("""
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+ SELECT series_aws_url, COUNT(*) as series_count
110
+ FROM index
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+ WHERE collection_id = 'your_collection_id'
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+ GROUP BY series_aws_url
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+ """)
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+
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+ print(results)
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+
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+ # Look for URLs containing 'idc-open-data-cr' or 'idc-open-data-two'
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+ # If present, that data won't be available in Google Healthcare endpoint
119
+ ```
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+
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+ ## Implementation Details
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+
123
+ IDC DICOMweb is provided through Google Cloud Healthcare API DICOM stores. The implementation follows DICOM PS3.18 Web Services with specific characteristics documented in the [Google Healthcare DICOM conformance statement](https://docs.cloud.google.com/healthcare-api/docs/dicom).
124
+
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+ ### Supported Operations
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+
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+ | Service | Description | Supported |
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+ |---------|-------------|-----------|
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+ | QIDO-RS | Search for DICOM objects | Yes |
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+ | WADO-RS | Retrieve DICOM objects and metadata | Yes |
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+ | STOW-RS | Store DICOM objects | No (IDC is read-only) |
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+
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+ **Not supported:** URI Service, Worklist Service, Non-Patient Instance Service, Capabilities Transactions
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+
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+ ### Searchable DICOM Tags (QIDO-RS)
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+
137
+ The implementation supports a limited set of searchable tags:
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+
139
+ | Level | Searchable Tags |
140
+ |-------|-----------------|
141
+ | Study | StudyInstanceUID, PatientName, PatientID, AccessionNumber, ReferringPhysicianName, StudyDate |
142
+ | Series | All study tags + SeriesInstanceUID, Modality |
143
+ | Instance | All series tags + SOPInstanceUID |
144
+
145
+ **Important:** Only exact matching is supported, except for:
146
+ - StudyDate: supports range queries
147
+ - PatientName: supports fuzzy matching
148
+
149
+ ### Query Limitations
150
+
151
+ - Maximum results: 5,000 for studies/series searches; 50,000 for instances
152
+ - Maximum offset: 1,000,000
153
+ - DICOM sequence tags larger than ~1 MB are not returned in metadata (BulkDataURI provided instead)
154
+
155
+ ## Code Examples
156
+
157
+ All examples use the public proxy endpoint. For authenticated access to Google Healthcare, see the [authentication section](#authentication-for-google-healthcare-api).
158
+
159
+ ### Finding UIDs with idc-index
160
+
161
+ Use `idc-index` to discover data, then use DICOMweb for metadata access:
162
+
163
+ ```python
164
+ from idc_index import IDCClient
165
+
166
+ client = IDCClient()
167
+
168
+ # Find studies of interest
169
+ results = client.sql_query("""
170
+ SELECT StudyInstanceUID, SeriesInstanceUID, PatientID, Modality
171
+ FROM index
172
+ WHERE collection_id = 'tcga_luad' AND Modality = 'CT'
173
+ LIMIT 5
174
+ """)
175
+
176
+ # Use these UIDs with DICOMweb
177
+ study_uid = results.iloc[0]['StudyInstanceUID']
178
+ series_uid = results.iloc[0]['SeriesInstanceUID']
179
+ print(f"Study: {study_uid}")
180
+ print(f"Series: {series_uid}")
181
+ ```
182
+
183
+ ### QIDO-RS: Search by UID
184
+
185
+ ```python
186
+ import requests
187
+
188
+ base_url = "https://proxy.imaging.datacommons.cancer.gov/current/viewer-only-no-downloads-see-tinyurl-dot-com-slash-3j3d9jyp/dicomWeb"
189
+
190
+ # Search for a specific study
191
+ study_uid = "1.3.6.1.4.1.14519.5.2.1.6450.9002.307623500513044641407722230440"
192
+ response = requests.get(
193
+ f"{base_url}/studies",
194
+ params={"StudyInstanceUID": study_uid},
195
+ headers={"Accept": "application/dicom+json"}
196
+ )
197
+
198
+ if response.status_code == 200:
199
+ studies = response.json()
200
+ print(f"Found {len(studies)} study")
201
+ ```
202
+
203
+ ### QIDO-RS: List Series in a Study
204
+
205
+ ```python
206
+ import requests
207
+
208
+ base_url = "https://proxy.imaging.datacommons.cancer.gov/current/viewer-only-no-downloads-see-tinyurl-dot-com-slash-3j3d9jyp/dicomWeb"
209
+ study_uid = "1.3.6.1.4.1.14519.5.2.1.6450.9002.307623500513044641407722230440"
210
+
211
+ response = requests.get(
212
+ f"{base_url}/studies/{study_uid}/series",
213
+ headers={"Accept": "application/dicom+json"}
214
+ )
215
+
216
+ if response.status_code == 200:
217
+ series_list = response.json()
218
+ for series in series_list:
219
+ # DICOM tags are returned as hex codes
220
+ series_uid = series.get("0020000E", {}).get("Value", [None])[0]
221
+ modality = series.get("00080060", {}).get("Value", [None])[0]
222
+ description = series.get("0008103E", {}).get("Value", [""])[0]
223
+ print(f"{modality}: {description}")
224
+ ```
225
+
226
+ ### QIDO-RS: List Instances in a Series
227
+
228
+ ```python
229
+ import requests
230
+
231
+ base_url = "https://proxy.imaging.datacommons.cancer.gov/current/viewer-only-no-downloads-see-tinyurl-dot-com-slash-3j3d9jyp/dicomWeb"
232
+ study_uid = "1.3.6.1.4.1.14519.5.2.1.6450.9002.307623500513044641407722230440"
233
+ series_uid = "1.3.6.1.4.1.14519.5.2.1.6450.9002.217441095430480124587725641302"
234
+
235
+ response = requests.get(
236
+ f"{base_url}/studies/{study_uid}/series/{series_uid}/instances",
237
+ params={"limit": 10},
238
+ headers={"Accept": "application/dicom+json"}
239
+ )
240
+
241
+ if response.status_code == 200:
242
+ instances = response.json()
243
+ print(f"Found {len(instances)} instances")
244
+ for inst in instances[:3]:
245
+ sop_uid = inst.get("00080018", {}).get("Value", [None])[0]
246
+ print(f" SOPInstanceUID: {sop_uid}")
247
+ ```
248
+
249
+ ### WADO-RS: Retrieve Series Metadata
250
+
251
+ ```python
252
+ import requests
253
+
254
+ base_url = "https://proxy.imaging.datacommons.cancer.gov/current/viewer-only-no-downloads-see-tinyurl-dot-com-slash-3j3d9jyp/dicomWeb"
255
+ study_uid = "1.3.6.1.4.1.14519.5.2.1.6450.9002.307623500513044641407722230440"
256
+ series_uid = "1.3.6.1.4.1.14519.5.2.1.6450.9002.217441095430480124587725641302"
257
+
258
+ response = requests.get(
259
+ f"{base_url}/studies/{study_uid}/series/{series_uid}/metadata",
260
+ headers={"Accept": "application/dicom+json"}
261
+ )
262
+
263
+ if response.status_code == 200:
264
+ instances = response.json()
265
+ print(f"Retrieved metadata for {len(instances)} instances")
266
+
267
+ # Extract image dimensions from first instance
268
+ if instances:
269
+ inst = instances[0]
270
+ rows = inst.get("00280010", {}).get("Value", [None])[0]
271
+ cols = inst.get("00280011", {}).get("Value", [None])[0]
272
+ print(f"Image dimensions: {rows} x {cols}")
273
+ ```
274
+
275
+ ### Combined Workflow: idc-index Discovery + DICOMweb Metadata
276
+
277
+ ```python
278
+ from idc_index import IDCClient
279
+ import requests
280
+
281
+ # Use idc-index for efficient discovery
282
+ idc = IDCClient()
283
+ results = idc.sql_query("""
284
+ SELECT StudyInstanceUID, SeriesInstanceUID, Modality, SeriesDescription
285
+ FROM index
286
+ WHERE collection_id = 'nlst' AND Modality = 'CT'
287
+ LIMIT 1
288
+ """)
289
+
290
+ study_uid = results.iloc[0]['StudyInstanceUID']
291
+ series_uid = results.iloc[0]['SeriesInstanceUID']
292
+ print(f"Found: {results.iloc[0]['SeriesDescription']}")
293
+
294
+ # Use DICOMweb to stream metadata without downloading files
295
+ base_url = "https://proxy.imaging.datacommons.cancer.gov/current/viewer-only-no-downloads-see-tinyurl-dot-com-slash-3j3d9jyp/dicomWeb"
296
+
297
+ response = requests.get(
298
+ f"{base_url}/studies/{study_uid}/series/{series_uid}/metadata",
299
+ headers={"Accept": "application/dicom+json"}
300
+ )
301
+
302
+ if response.status_code == 200:
303
+ metadata = response.json()
304
+ print(f"Retrieved metadata for {len(metadata)} instances without downloading files")
305
+ ```
306
+
307
+ ## Common DICOM Tags Reference
308
+
309
+ DICOMweb returns tags as hexadecimal codes. Common tags:
310
+
311
+ | Tag | Name | Description |
312
+ |-----|------|-------------|
313
+ | 00080018 | SOPInstanceUID | Unique instance identifier |
314
+ | 00080020 | StudyDate | Date study was performed |
315
+ | 00080060 | Modality | Imaging modality (CT, MR, PT, etc.) |
316
+ | 0008103E | SeriesDescription | Description of series |
317
+ | 00100020 | PatientID | Patient identifier |
318
+ | 0020000D | StudyInstanceUID | Unique study identifier |
319
+ | 0020000E | SeriesInstanceUID | Unique series identifier |
320
+ | 00280010 | Rows | Image height in pixels |
321
+ | 00280011 | Columns | Image width in pixels |
322
+
323
+ ## Authentication for Google Healthcare API
324
+
325
+ To use the Google Healthcare endpoint with higher quotas:
326
+
327
+ ```python
328
+ from google.auth import default
329
+ from google.auth.transport.requests import Request
330
+ import requests
331
+
332
+ # Get credentials (requires gcloud auth)
333
+ credentials, project = default()
334
+ credentials.refresh(Request())
335
+
336
+ # Build authenticated request
337
+ base_url = "https://healthcare.googleapis.com/v1/projects/nci-idc-data/locations/us-central1/datasets/idc/dicomStores/idc-store-v23/dicomWeb"
338
+
339
+ response = requests.get(
340
+ f"{base_url}/studies",
341
+ params={"limit": 5},
342
+ headers={
343
+ "Authorization": f"Bearer {credentials.token}",
344
+ "Accept": "application/dicom+json"
345
+ }
346
+ )
347
+ ```
348
+
349
+ **Prerequisites:**
350
+ 1. Google Cloud SDK installed (`gcloud`)
351
+ 2. Authenticated: `gcloud auth application-default login`
352
+ 3. Account has access to public Google Cloud datasets
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+
354
+ ## Troubleshooting
355
+
356
+ ### Issue: 400 Bad Request on search queries
357
+ - **Cause:** Using unsupported search parameters. The implementation only supports specific DICOM tags for filtering.
358
+ - **Solution:** Use UID-based queries (StudyInstanceUID, SeriesInstanceUID). For filtering by Modality or other attributes, use `idc-index` to discover UIDs first, then query DICOMweb with specific UIDs.
359
+
360
+ ### Issue: 403 Forbidden on Google Healthcare endpoint
361
+ - **Cause:** Missing authentication or insufficient permissions
362
+ - **Solution:** Run `gcloud auth application-default login` and ensure your account has access
363
+
364
+ ### Issue: 429 Too Many Requests
365
+ - **Cause:** Rate limit exceeded
366
+ - **Solution:** Add delays between requests, reduce `limit` values, or use authenticated endpoint for higher quotas
367
+
368
+ ### Issue: 204 No Content for valid UIDs
369
+ - **Cause:** UID may be from an older IDC version not in current data, or data is in buckets not replicated by Google Healthcare
370
+ - **Solution:**
371
+ - Verify UID exists using `idc-index` query first
372
+ - Check if data is in `idc-open-data-cr` or `idc-open-data-two` buckets (not available in Google Healthcare endpoint)
373
+ - Switch to IDC public proxy for 100% coverage
374
+ - During new version releases, Google Healthcare may lag 1-2 weeks behind
375
+
376
+ ### Issue: Large metadata responses slow to parse
377
+ - **Cause:** Series with many instances returns large JSON
378
+ - **Solution:** Use `limit` parameter on instance queries, or query specific instances by SOPInstanceUID
379
+
380
+ ### Issue: Response missing expected attributes
381
+ - **Cause:** DICOM sequences larger than ~1 MB are excluded from metadata responses
382
+ - **Solution:** Retrieve the full DICOM instance using WADO-RS instance retrieval if you need all attributes
383
+
384
+ ## Resources
385
+
386
+ **IDC Documentation:**
387
+ - [IDC DICOM Stores](https://learn.canceridc.dev/data/organization-of-data/dicom-stores) - Data coverage and bucket details
388
+ - [IDC DICOMweb Access](https://learn.canceridc.dev/data/downloading-data/dicomweb-access) - Endpoint usage and differences
389
+ - [IDC Proxy Policy](https://learn.canceridc.dev/portal/proxy-policy) - Quota policies and usage restrictions
390
+ - [IDC User Guide](https://learn.canceridc.dev/) - Complete documentation
391
+
392
+ **DICOMweb Standards and Tools:**
393
+ - [Google Healthcare DICOM Conformance Statement](https://docs.cloud.google.com/healthcare-api/docs/dicom)
394
+ - [DICOMweb Standard](https://www.dicomstandard.org/using/dicomweb)
395
+ - [dicomweb-client Python library](https://dicomweb-client.readthedocs.io/)
396
+
397
+ **Related Guides:**
398
+ - `cloud_storage_guide.md` - Direct bucket access, file organization, CRDC UUIDs, and versioning
399
+ - `bigquery_guide.md` - Advanced metadata queries with full DICOM attributes