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- data/ext/bamtools/src/utils/CMakeFiles/BamTools-utils.dir/flags.make +8 -0
- data/ext/bamtools/src/utils/CMakeFiles/BamTools-utils.dir/link.txt +1 -0
- data/ext/bamtools/src/utils/CMakeFiles/BamTools-utils.dir/progress.make +5 -0
- data/ext/bamtools/src/utils/CMakeFiles/CMakeDirectoryInformation.cmake +23 -0
- data/ext/bamtools/src/utils/CMakeFiles/progress.marks +1 -0
- data/ext/bamtools/src/utils/CMakeLists.txt +30 -0
- data/ext/bamtools/src/utils/Makefile +290 -0
- data/ext/bamtools/src/utils/bamtools_fasta.cpp +632 -0
- data/ext/bamtools/src/utils/bamtools_fasta.h +47 -0
- data/ext/bamtools/src/utils/bamtools_filter_engine.h +552 -0
- data/ext/bamtools/src/utils/bamtools_filter_properties.h +195 -0
- data/ext/bamtools/src/utils/bamtools_filter_ruleparser.h +319 -0
- data/ext/bamtools/src/utils/bamtools_options.cpp +287 -0
- data/ext/bamtools/src/utils/bamtools_options.h +213 -0
- data/ext/bamtools/src/utils/bamtools_pileup_engine.cpp +327 -0
- data/ext/bamtools/src/utils/bamtools_pileup_engine.h +94 -0
- data/ext/bamtools/src/utils/bamtools_utilities.cpp +333 -0
- data/ext/bamtools/src/utils/bamtools_utilities.h +67 -0
- data/ext/bamtools/src/utils/bamtools_variant.h +128 -0
- data/ext/bamtools/src/utils/cmake_install.cmake +29 -0
- data/ext/bamtools/src/utils/utils_global.h +21 -0
- data/lib/ngs_server/version.rb +3 -0
- data/lib/ngs_server.rb +3 -0
- data/ngs_server.gemspec +23 -0
- metadata +339 -0
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// ***************************************************************************
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// bamtools_filter_engine.h (c) 2010 Derek Barnett, Erik Garrison
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// Marth Lab, Department of Biology, Boston College
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// ---------------------------------------------------------------------------
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// Last modified: 19 November 2010
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// ---------------------------------------------------------------------------
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// Provides a generic filter engine based on filter-sets of properties,
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// with possible "rules" (compound logical expressions) to create more complex
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// queries on a data set.
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//
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// FilterEngine consists, most importantly, of :
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//
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// a list of possible properties (each tagged whether it has been 'enabled' as a filter)
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// a map of filterName => propertySet
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// queue for compound rule expression (i.e. "(filter1 AND filter2) OR !filter3" )
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//
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// Each propertySet is a list of properties enabled for this particular filter object
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//
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// Implemented as a map of propertyNames to propertyFilterValue
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// ( "property1" => pfv1
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// "property2" => pfv2
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// "property4" => pfv4
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// etc. )
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//
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// Any properties that are 'possible', via FilterEngine::addProperty(), but not enabled
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// via FilterEngine::setProperty() (in our example, say "property3"), evaluate to true
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// for any query. Meaning that if a property is not set on this filter, we don't care
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// about it here, so it passes though OK.
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//
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// A propertyFilterValue contains a value and comparison type
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//
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// ( pfv1: Value = 50, Type = GREATER_THAN_EQUAL
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// pfv2: Value = "foo", Type = STARTS_WITH
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// pfv4: Value = "bar", Type = CONTAINS
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// etc. )
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//
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// This allows for more complex queries (than simple isEqual?) against a variety of data types.
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//
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// ***************************************************************************
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#ifndef BAMTOOLS_FILTER_ENGINE_H
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#define BAMTOOLS_FILTER_ENGINE_H
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#include <utils/bamtools_filter_properties.h>
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#include <utils/bamtools_filter_ruleparser.h>
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#include <utils/bamtools_utilities.h>
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#include <utils/utils_global.h>
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#include <algorithm>
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#include <iostream>
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#include <map>
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#include <queue>
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#include <sstream>
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#include <stack>
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#include <string>
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#include <utility>
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#include <vector>
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namespace BamTools {
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struct UTILS_EXPORT FilterCompareType {
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enum Type { AND = 0
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, NOT
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, OR
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};
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};
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// -----------------------------------------------------------
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// FilterEngine
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template <typename FilterChecker>
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class UTILS_EXPORT FilterEngine {
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// ctor & dtor
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public:
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FilterEngine(void)
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: m_ruleString("")
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, m_isRuleQueueGenerated(false)
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, m_defaultCompareType(FilterCompareType::OR)
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, AND_OPERATOR("&")
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, OR_OPERATOR("|")
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, NOT_OPERATOR("!")
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{ }
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~FilterEngine(void) { }
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// 'filter set' methods
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public:
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// creates a new filter set, returns true if created, false if error or already exists
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bool addFilter(const std::string& filterName);
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// return list of current filter names
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const std::vector<std::string> filterNames(void);
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// 'property' methods
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public:
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// add a new known property (& type) to engine
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bool addProperty(const std::string& propertyName);
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// sets property filter (value, type) for propertyName, on a particular filter set
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// setProperty("filter1", "mapQuality", 50, GREATER_THAN_EQUAL)
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template<typename T>
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bool setProperty(const std::string& filterName,
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const std::string& propertyName,
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const T& value,
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const PropertyFilterValue::ValueCompareType& type = PropertyFilterValue::EXACT);
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// returns list of all properties known by FilterEngine ( any created using addProperty() )
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const std::vector<std::string> allPropertyNames(void);
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// returns list of property names that are 'enabled' ( only those touched by setProperty() )
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const std::vector<std::string> enabledPropertyNames(void);
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// 'rule' methods
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public:
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// sets comparison operator between filters if no rule string given
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// default is to do an OR on each filter
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void setDefaultCompareType(const FilterCompareType::Type& type = FilterCompareType::OR);
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// sets rule string for building expression queue
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// if empty, creates
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void setRule(const std::string& ruleString = "");
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// token parsing (for property filter generation)
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public:
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template<typename T>
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static bool parseToken(const std::string& token, T& value, PropertyFilterValue::ValueCompareType& type);
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// query evaluation
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public:
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// returns true if query passes all filters in FilterEngine
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template<typename T>
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bool check(const T& query);
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// internal rule-handling methods
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private:
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void buildDefaultRuleString(void);
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void buildRuleQueue(void);
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template<typename T>
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bool evaluateFilterRules(const T& query);
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// data members
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private:
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// all 'filter sets'
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FilterMap m_filters;
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// all known properties
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std::vector<Property> m_properties;
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// infix expression of filter-set comparison rules
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std::string m_ruleString;
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// postfix expression of tokens (filterNames) and operators (as strings)
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// if this is empty, uses m_compareType to build default expression queue
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std::queue<std::string> m_ruleQueue;
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// flag to test if the rule expression queue has been generated
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bool m_isRuleQueueGenerated;
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// 'default' comparison operator between filters if no rule string given
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// if this is changed, m_ruleString is used to build new m_ruleQueue
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FilterCompareType::Type m_defaultCompareType;
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// client-specified checking type ( provides method: bool check(PropertyFilter, T object) )
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FilterChecker m_checker;
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// token-parsing constants
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static const int NOT_CHAR = (int)'!';
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static const int EQUAL_CHAR = (int)'=';
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static const int GREATER_THAN_CHAR = (int)'>';
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static const int LESS_THAN_CHAR = (int)'<';
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static const int WILDCARD_CHAR = (int)'*';
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// filter evaluation constants
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const std::string AND_OPERATOR;
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const std::string OR_OPERATOR;
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const std::string NOT_OPERATOR;
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};
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// creates a new filter set, returns true if created, false if error or already exists
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template<typename FilterChecker>
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inline bool FilterEngine<FilterChecker>::addFilter(const std::string& filterName) {
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return (m_filters.insert(std::make_pair(filterName, PropertyFilter()))).second;
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}
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// add a new known property & type to engine
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template<typename FilterChecker>
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inline bool FilterEngine<FilterChecker>::addProperty(const std::string& propertyName) {
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const std::vector<std::string> propertyNames = allPropertyNames();
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bool found = std::binary_search( propertyNames.begin(), propertyNames.end(), propertyName );
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if ( found ) return false;
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m_properties.push_back( Property(propertyName) );
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std::sort( m_properties.begin(), m_properties.end() );
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return true;
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}
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// returns list of all properties known by FilterEngine
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// ( any that were created using addProperty() )
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template<typename FilterChecker>
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inline const std::vector<std::string> FilterEngine<FilterChecker>::allPropertyNames(void) {
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// set up stringlist
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std::vector<std::string> names;
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names.reserve(m_properties.size());
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// iterate through all properties, appending to stringlist
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std::vector<Property>::const_iterator propIter = m_properties.begin();
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std::vector<Property>::const_iterator propEnd = m_properties.end();
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for ( ; propIter != propEnd; ++propIter )
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names.push_back( (*propIter).Name );
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// return stringlist
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return names;
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}
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// builds a default rule string based on m_defaultCompareType
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// used if user supplied an explicit rule string
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template<typename FilterChecker>
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inline void FilterEngine<FilterChecker>::buildDefaultRuleString(void) {
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// set up temp string stream
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std::stringstream ruleStream("");
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// get first filterName
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FilterMap::const_iterator mapIter = m_filters.begin();
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ruleStream << (*mapIter).first;
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// if there are more filters present
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// iterate over remaining filters, appending compare operator and filter name
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if ( m_filters.size() > 1 ) {
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for ( ++mapIter ; mapIter != m_filters.end(); ++mapIter )
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ruleStream << ( (m_defaultCompareType == FilterCompareType::AND) ? " & " : " | " )
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<< (*mapIter).first;
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}
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// set m_ruleString from temp stream
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m_ruleString = ruleStream.str();
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}
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// build expression queue based on ruleString
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template<typename FilterChecker>
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inline void FilterEngine<FilterChecker>::buildRuleQueue(void) {
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// skip if no filters present
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if ( m_filters.empty() ) return;
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// clear out any prior expression queue data
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while ( !m_ruleQueue.empty() )
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m_ruleQueue.pop();
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// create a rule string, if not provided
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if ( m_ruleString.empty() )
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buildDefaultRuleString();
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// initialize RuleParser, run, and retrieve results
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RuleParser ruleParser(m_ruleString);
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ruleParser.parse();
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m_ruleQueue = ruleParser.results();
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// set flag if rule queue contains any values
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m_isRuleQueueGenerated = (!m_ruleQueue.empty());
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}
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// returns whether query value passes filter engine rules
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template<class FilterChecker> template<typename T>
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bool FilterEngine<FilterChecker>::check(const T& query) {
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// return result of querying against filter rules
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return evaluateFilterRules(query);
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}
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// returns list of property names that are 'enabled' ( only those touched by setProperty() )
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template<typename FilterChecker>
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inline const std::vector<std::string> FilterEngine<FilterChecker>::enabledPropertyNames(void) {
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// initialize stringlist
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std::vector<std::string> names;
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names.reserve(m_properties.size());
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// iterate over all properties, appending if enabled
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std::vector<Property>::const_iterator propIter = m_properties.begin();
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std::vector<Property>::const_iterator propEnd = m_properties.end();
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for ( ; propIter != propEnd; ++propIter )
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if ( (*propIter).IsEnabled )
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names.push_back( (*propIter).Name );
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// return stringlist
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return names;
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}
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// evaluates postfix rule queue - with each filter as an operand, AND|OR|NOT as operators
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template<class FilterChecker> template<typename T>
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bool FilterEngine<FilterChecker>::evaluateFilterRules(const T& query) {
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// build ruleQueue if not done before
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if ( !m_isRuleQueueGenerated )
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buildRuleQueue();
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std::stack<bool> resultStack;
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FilterMap::const_iterator filterIter;
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FilterMap::const_iterator filterEnd = m_filters.end();
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std::queue<std::string> ruleQueueCopy = m_ruleQueue;
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while ( !ruleQueueCopy.empty() ) {
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const std::string& token = ruleQueueCopy.front();
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// token is NOT_OPERATOR
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if ( token == FilterEngine<FilterChecker>::NOT_OPERATOR ) {
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BAMTOOLS_ASSERT_MESSAGE( !resultStack.empty(), "Empty result stack - cannot apply operator: !" );
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resultStack.top() = !resultStack.top();
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}
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// token is AND_OPERATOR
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else if ( token == FilterEngine<FilterChecker>::AND_OPERATOR ) {
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BAMTOOLS_ASSERT_MESSAGE( resultStack.size() >= 2 , "Not enough operands - cannot apply operator: &" );
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bool topResult = resultStack.top();
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resultStack.pop();
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resultStack.top() &= topResult;
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}
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// token is OR_OPERATOR
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else if ( token == FilterEngine<FilterChecker>::OR_OPERATOR ) {
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BAMTOOLS_ASSERT_MESSAGE( resultStack.size() >= 2 , "Not enough operands - cannot apply operator: |" );
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bool topResult = resultStack.top();
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resultStack.pop();
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resultStack.top() |= topResult;
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}
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// token is an operand
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else {
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// look up PropertyFilter that matches this token
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filterIter = m_filters.find(token);
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BAMTOOLS_ASSERT_MESSAGE( (filterIter != filterEnd), "Filter mentioned in rule, not found in FilterEngine" );
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const PropertyFilter& filter = (*filterIter).second;
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bool result = m_checker.check(filter, query);
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resultStack.push( result );
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}
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// pop token from ruleQueue
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ruleQueueCopy.pop();
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}
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// return last result
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BAMTOOLS_ASSERT_MESSAGE( resultStack.size() == 1, "Result stack should only have one value remaining - cannot return result" );
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return resultStack.top();
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}
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|
+
// return list of current filter names
|
343
|
+
template<typename FilterChecker>
|
344
|
+
inline const std::vector<std::string> FilterEngine<FilterChecker>::filterNames(void) {
|
345
|
+
// initialize stringlist
|
346
|
+
std::vector<std::string> names;
|
347
|
+
names.reserve(m_filters.size());
|
348
|
+
// iterate over all filters, appending filter name
|
349
|
+
FilterMap::const_iterator mapIter = m_filters.begin();
|
350
|
+
FilterMap::const_iterator mapEnd = m_filters.end();
|
351
|
+
for ( ; mapIter != mapEnd; ++mapIter )
|
352
|
+
names.push_back( (*mapIter).first );
|
353
|
+
// return stringlist
|
354
|
+
return names;
|
355
|
+
}
|
356
|
+
|
357
|
+
// parse a filterValue token string that may contain comparison qualifiers (">50", "*SRR", etc.)
|
358
|
+
template<class FilterChecker> template<typename T>
|
359
|
+
bool FilterEngine<FilterChecker>::parseToken(const std::string& token, T& value, PropertyFilterValue::ValueCompareType& type) {
|
360
|
+
|
361
|
+
// skip if token is empty
|
362
|
+
if ( token.empty() ) return false;
|
363
|
+
|
364
|
+
// will store token after special chars are removed
|
365
|
+
std::string strippedToken;
|
366
|
+
|
367
|
+
// if only single character
|
368
|
+
if ( token.length() == 1 ) {
|
369
|
+
strippedToken = token;
|
370
|
+
type = PropertyFilterValue::EXACT;
|
371
|
+
}
|
372
|
+
|
373
|
+
// more than one character, check for special chars
|
374
|
+
else {
|
375
|
+
const int firstChar = (int)token.at(0);
|
376
|
+
switch ( firstChar ) {
|
377
|
+
|
378
|
+
case ( FilterEngine<FilterChecker>::NOT_CHAR ) :
|
379
|
+
strippedToken = token.substr(1);
|
380
|
+
type = PropertyFilterValue::NOT;
|
381
|
+
break;
|
382
|
+
|
383
|
+
case ( FilterEngine<FilterChecker>::GREATER_THAN_CHAR ) :
|
384
|
+
|
385
|
+
// check for '>=' case
|
386
|
+
if ( token.at(1) == FilterEngine<FilterChecker>::EQUAL_CHAR ) {
|
387
|
+
if ( token.length() == 2 ) return false;
|
388
|
+
strippedToken = token.substr(2);
|
389
|
+
type = PropertyFilterValue::GREATER_THAN_EQUAL;
|
390
|
+
}
|
391
|
+
|
392
|
+
// otherwise only '>'
|
393
|
+
else {
|
394
|
+
strippedToken = token.substr(1);
|
395
|
+
type = PropertyFilterValue::GREATER_THAN;
|
396
|
+
}
|
397
|
+
|
398
|
+
break;
|
399
|
+
|
400
|
+
case ( FilterEngine<FilterChecker>::LESS_THAN_CHAR ) :
|
401
|
+
|
402
|
+
// check for '<=' case
|
403
|
+
if ( token.at(1) == FilterEngine<FilterChecker>::EQUAL_CHAR ) {
|
404
|
+
if ( token.length() == 2 ) return false;
|
405
|
+
strippedToken = token.substr(2);
|
406
|
+
type = PropertyFilterValue::LESS_THAN_EQUAL;
|
407
|
+
}
|
408
|
+
|
409
|
+
// otherwise only '<'
|
410
|
+
else {
|
411
|
+
strippedToken = token.substr(1);
|
412
|
+
type = PropertyFilterValue::LESS_THAN;
|
413
|
+
}
|
414
|
+
|
415
|
+
break;
|
416
|
+
|
417
|
+
case ( FilterEngine<FilterChecker>::WILDCARD_CHAR ) :
|
418
|
+
|
419
|
+
// check for *str* case (CONTAINS)
|
420
|
+
if ( token.at( token.length() - 1 ) == FilterEngine<FilterChecker>::WILDCARD_CHAR ) {
|
421
|
+
if ( token.length() == 2 ) return false;
|
422
|
+
strippedToken = token.substr(1, token.length() - 2);
|
423
|
+
type = PropertyFilterValue::CONTAINS;
|
424
|
+
}
|
425
|
+
|
426
|
+
// otherwise *str case (ENDS_WITH)
|
427
|
+
else {
|
428
|
+
strippedToken = token.substr(1);
|
429
|
+
type = PropertyFilterValue::ENDS_WITH;
|
430
|
+
}
|
431
|
+
|
432
|
+
break;
|
433
|
+
|
434
|
+
default :
|
435
|
+
// check for str* case (STARTS_WITH)
|
436
|
+
if ( token.at( token.length() - 1 ) == FilterEngine<FilterChecker>::WILDCARD_CHAR ) {
|
437
|
+
if ( token.length() == 2 ) return false;
|
438
|
+
strippedToken = token.substr(0, token.length() - 1);
|
439
|
+
type = PropertyFilterValue::STARTS_WITH;
|
440
|
+
}
|
441
|
+
|
442
|
+
// otherwise EXACT
|
443
|
+
else {
|
444
|
+
strippedToken = token;
|
445
|
+
type = PropertyFilterValue::EXACT;
|
446
|
+
}
|
447
|
+
|
448
|
+
break;
|
449
|
+
}
|
450
|
+
}
|
451
|
+
|
452
|
+
// convert stripped token to value
|
453
|
+
std::stringstream stream(strippedToken);
|
454
|
+
if ( strippedToken == "true" || strippedToken == "false" )
|
455
|
+
stream >> std::boolalpha >> value;
|
456
|
+
else
|
457
|
+
stream >> value;
|
458
|
+
|
459
|
+
// check for valid CompareType on type T
|
460
|
+
Variant variantCheck = value;
|
461
|
+
|
462
|
+
// if T is not string AND CompareType is for string values, return false
|
463
|
+
if ( !variantCheck.is_type<std::string>() ) {
|
464
|
+
if ( type == PropertyFilterValue::CONTAINS ||
|
465
|
+
type == PropertyFilterValue::ENDS_WITH ||
|
466
|
+
type == PropertyFilterValue::STARTS_WITH )
|
467
|
+
|
468
|
+
return false;
|
469
|
+
}
|
470
|
+
|
471
|
+
// return success
|
472
|
+
return true;
|
473
|
+
}
|
474
|
+
|
475
|
+
// sets comparison operator between filters if no rule string given
|
476
|
+
// default is to do an OR on each filter
|
477
|
+
template<typename FilterChecker>
|
478
|
+
inline void FilterEngine<FilterChecker>::setDefaultCompareType(const FilterCompareType::Type& type) {
|
479
|
+
// check for supported compare type
|
480
|
+
if ( type == FilterCompareType::AND || type == FilterCompareType::OR ) {
|
481
|
+
// if not the current compare type
|
482
|
+
if ( m_defaultCompareType != type ) {
|
483
|
+
m_defaultCompareType = type;
|
484
|
+
buildRuleQueue();
|
485
|
+
}
|
486
|
+
}
|
487
|
+
}
|
488
|
+
|
489
|
+
// sets property filter (value, type) for propertyName, on a particular filter set
|
490
|
+
// setProperty("filter1", "mapQuality", 50, GREATER_THAN_EQUAL)
|
491
|
+
template<class FilterChecker> template<typename T>
|
492
|
+
bool FilterEngine<FilterChecker>::setProperty(const std::string& filterName,
|
493
|
+
const std::string& propertyName,
|
494
|
+
const T& value,
|
495
|
+
const PropertyFilterValue::ValueCompareType& type)
|
496
|
+
{
|
497
|
+
// lookup filter by name, return false if not found
|
498
|
+
FilterMap::iterator filterIter = m_filters.find(filterName);
|
499
|
+
if ( filterIter == m_filters.end() ) return false;
|
500
|
+
|
501
|
+
// lookup property for filter, add new PropertyFilterValue if not found, modify if already exists
|
502
|
+
PropertyFilter& filter = (*filterIter).second;
|
503
|
+
PropertyMap::iterator propertyIter = filter.Properties.find(propertyName);
|
504
|
+
|
505
|
+
bool success;
|
506
|
+
|
507
|
+
// property not found for this filter, create new entry
|
508
|
+
if ( propertyIter == filter.Properties.end() )
|
509
|
+
success = (filter.Properties.insert(std::make_pair(propertyName, PropertyFilterValue(value, type)))).second;
|
510
|
+
|
511
|
+
// property already exists, modify
|
512
|
+
else {
|
513
|
+
PropertyFilterValue& filterValue = (*propertyIter).second;
|
514
|
+
filterValue.Value = value;
|
515
|
+
filterValue.Type = type;
|
516
|
+
success = true;
|
517
|
+
}
|
518
|
+
|
519
|
+
// if error so far, return false
|
520
|
+
if ( !success ) return false;
|
521
|
+
|
522
|
+
// --------------------------------------------
|
523
|
+
// otherwise, set Property.IsEnabled to true
|
524
|
+
|
525
|
+
// lookup property
|
526
|
+
std::vector<Property>::iterator knownPropertyIter = std::find( m_properties.begin(), m_properties.end(), propertyName);
|
527
|
+
|
528
|
+
// if not found, create a new (enabled) entry (& re-sort list)
|
529
|
+
if ( knownPropertyIter == m_properties.end() ) {
|
530
|
+
m_properties.push_back( Property(propertyName, true) );
|
531
|
+
std::sort( m_properties.begin(), m_properties.end() );
|
532
|
+
}
|
533
|
+
|
534
|
+
// property already known, set as enabled
|
535
|
+
else (*knownPropertyIter).IsEnabled = true;
|
536
|
+
|
537
|
+
// return success
|
538
|
+
return true;
|
539
|
+
}
|
540
|
+
|
541
|
+
// sets user-specified rule string & signals update of rule-expression queue
|
542
|
+
template<typename FilterChecker>
|
543
|
+
inline void FilterEngine<FilterChecker>::setRule(const std::string& ruleString) {
|
544
|
+
if ( m_ruleString != ruleString) {
|
545
|
+
m_ruleString = ruleString;
|
546
|
+
buildRuleQueue();
|
547
|
+
}
|
548
|
+
}
|
549
|
+
|
550
|
+
} // namespace BamTools
|
551
|
+
|
552
|
+
#endif // BAMTOOLS_FILTER_ENGINE_H
|