bio-polymarker 1.3.2
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- checksums.yaml +7 -0
- data/.travis.yml +24 -0
- data/Gemfile +23 -0
- data/README.md +205 -0
- data/Rakefile +61 -0
- data/SECURITY.md +16 -0
- data/VERSION +1 -0
- data/bin/bfr.rb +128 -0
- data/bin/blast_triads.rb +166 -0
- data/bin/blast_triads_promoters.rb +192 -0
- data/bin/count_variations.rb +36 -0
- data/bin/filter_blat_by_target_coverage.rb +69 -0
- data/bin/filter_exonerate_by_identity.rb +38 -0
- data/bin/find_best_blat_hit.rb +33 -0
- data/bin/find_best_exonerate.rb +17 -0
- data/bin/get_longest_hsp_blastx_triads.rb +66 -0
- data/bin/hexaploid_primers.rb +168 -0
- data/bin/homokaryot_primers.rb +183 -0
- data/bin/mafft_triads.rb +120 -0
- data/bin/mafft_triads_promoters.rb +403 -0
- data/bin/map_markers_to_contigs.rb +66 -0
- data/bin/marker_to_vcf.rb +241 -0
- data/bin/markers_in_region.rb +42 -0
- data/bin/mask_triads.rb +169 -0
- data/bin/polymarker.rb +410 -0
- data/bin/polymarker_capillary.rb +443 -0
- data/bin/polymarker_deletions.rb +350 -0
- data/bin/snp_position_to_polymarker.rb +101 -0
- data/bin/snps_between_bams.rb +107 -0
- data/bin/tag_stats.rb +75 -0
- data/bin/vcfLineToTable.rb +56 -0
- data/bin/vcfToPolyMarker.rb +82 -0
- data/bio-polymarker.gemspec +227 -0
- data/conf/defaults.rb +1 -0
- data/conf/primer3_config/dangle.dh +128 -0
- data/conf/primer3_config/dangle.ds +128 -0
- data/conf/primer3_config/interpretations/dangle_i.dh +131 -0
- data/conf/primer3_config/interpretations/dangle_i.ds +131 -0
- data/conf/primer3_config/interpretations/loops_i.dh +34 -0
- data/conf/primer3_config/interpretations/loops_i.ds +31 -0
- data/conf/primer3_config/interpretations/stack_i.dh +257 -0
- data/conf/primer3_config/interpretations/stack_i.ds +256 -0
- data/conf/primer3_config/interpretations/stackmm_i_mm.dh +257 -0
- data/conf/primer3_config/interpretations/stackmm_i_mm.ds +256 -0
- data/conf/primer3_config/interpretations/tetraloop_i.dh +79 -0
- data/conf/primer3_config/interpretations/tetraloop_i.ds +81 -0
- data/conf/primer3_config/interpretations/triloop_i.dh +21 -0
- data/conf/primer3_config/interpretations/triloop_i.ds +18 -0
- data/conf/primer3_config/interpretations/tstack2_i.dh +256 -0
- data/conf/primer3_config/interpretations/tstack2_i.ds +256 -0
- data/conf/primer3_config/interpretations/tstack_i.dh +256 -0
- data/conf/primer3_config/interpretations/tstack_i.ds +256 -0
- data/conf/primer3_config/interpretations/tstack_tm_inf_i.dh +256 -0
- data/conf/primer3_config/interpretations/tstack_tm_inf_i.ds +256 -0
- data/conf/primer3_config/loops.dh +30 -0
- data/conf/primer3_config/loops.ds +30 -0
- data/conf/primer3_config/stack.dh +256 -0
- data/conf/primer3_config/stack.ds +256 -0
- data/conf/primer3_config/stackmm.dh +256 -0
- data/conf/primer3_config/stackmm.ds +256 -0
- data/conf/primer3_config/tetraloop.dh +77 -0
- data/conf/primer3_config/tetraloop.ds +77 -0
- data/conf/primer3_config/triloop.dh +16 -0
- data/conf/primer3_config/triloop.ds +16 -0
- data/conf/primer3_config/tstack.dh +256 -0
- data/conf/primer3_config/tstack2.dh +256 -0
- data/conf/primer3_config/tstack2.ds +256 -0
- data/conf/primer3_config/tstack_tm_inf.ds +256 -0
- data/lib/bio/BFRTools.rb +465 -0
- data/lib/bio/BIOExtensions.rb +153 -0
- data/lib/bio/PolyploidTools/ChromosomeArm.rb +63 -0
- data/lib/bio/PolyploidTools/ExonContainer.rb +245 -0
- data/lib/bio/PolyploidTools/Marker.rb +175 -0
- data/lib/bio/PolyploidTools/Mask.rb +116 -0
- data/lib/bio/PolyploidTools/NoSNPSequence.rb +292 -0
- data/lib/bio/PolyploidTools/PrimerRegion.rb +30 -0
- data/lib/bio/PolyploidTools/SNP.rb +804 -0
- data/lib/bio/PolyploidTools/SNPMutant.rb +86 -0
- data/lib/bio/PolyploidTools/SNPSequence.rb +55 -0
- data/lib/bio/db/blast.rb +114 -0
- data/lib/bio/db/exonerate.rb +333 -0
- data/lib/bio/db/primer3.rb +820 -0
- data/lib/bio-polymarker.rb +28 -0
- data/test/data/7B_amplicon_test.fa +12 -0
- data/test/data/7B_amplicon_test.fa.fai +1 -0
- data/test/data/7B_amplicon_test_reference.fa +110 -0
- data/test/data/7B_amplicon_test_reference.fa.fai +3 -0
- data/test/data/7B_marker_test.txt +1 -0
- data/test/data/BS00068396_51.fa +2 -0
- data/test/data/BS00068396_51_blast.tab +4 -0
- data/test/data/BS00068396_51_contigs.aln +1412 -0
- data/test/data/BS00068396_51_contigs.dnd +7 -0
- data/test/data/BS00068396_51_contigs.fa +8 -0
- data/test/data/BS00068396_51_contigs.fa.fai +4 -0
- data/test/data/BS00068396_51_contigs.fa.nhr +0 -0
- data/test/data/BS00068396_51_contigs.fa.nin +0 -0
- data/test/data/BS00068396_51_contigs.fa.nsq +0 -0
- data/test/data/BS00068396_51_contigs.nhr +0 -0
- data/test/data/BS00068396_51_contigs.nin +0 -0
- data/test/data/BS00068396_51_contigs.nsq +0 -0
- data/test/data/BS00068396_51_exonerate.tab +6 -0
- data/test/data/BS00068396_51_for_polymarker.txt +1 -0
- data/test/data/BS00068396_51_genes.txt +14 -0
- data/test/data/IWGSC_CSS_1AL_scaff_1455974.fa +112 -0
- data/test/data/IWGSC_CSS_1AL_scaff_1455974_aln_contigs.fa +2304 -0
- data/test/data/IWGSC_CSS_1AL_scaff_1455974_aln_contigs.fa.fai +11 -0
- data/test/data/LIB1716.bam +0 -0
- data/test/data/LIB1716.bam.bai +0 -0
- data/test/data/LIB1719.bam +0 -0
- data/test/data/LIB1719.bam.bai +0 -0
- data/test/data/LIB1721.bam +0 -0
- data/test/data/LIB1721.bam.bai +0 -0
- data/test/data/LIB1722.bam +0 -0
- data/test/data/LIB1722.bam.bai +0 -0
- data/test/data/PST130_7067.csv +1 -0
- data/test/data/PST130_7067.fa +2 -0
- data/test/data/PST130_7067.fa.fai +1 -0
- data/test/data/PST130_7067.fa.ndb +0 -0
- data/test/data/PST130_7067.fa.nhr +0 -0
- data/test/data/PST130_7067.fa.nin +0 -0
- data/test/data/PST130_7067.fa.not +0 -0
- data/test/data/PST130_7067.fa.nsq +0 -0
- data/test/data/PST130_7067.fa.ntf +0 -0
- data/test/data/PST130_7067.fa.nto +0 -0
- data/test/data/PST130_reverse_primer.csv +1 -0
- data/test/data/S22380157.fa +16 -0
- data/test/data/S22380157.fa.fai +1 -0
- data/test/data/S22380157.vcf +67 -0
- data/test/data/S58861868/LIB1716.bam +0 -0
- data/test/data/S58861868/LIB1716.sam +651 -0
- data/test/data/S58861868/LIB1719.bam +0 -0
- data/test/data/S58861868/LIB1719.sam +805 -0
- data/test/data/S58861868/LIB1721.bam +0 -0
- data/test/data/S58861868/LIB1721.sam +1790 -0
- data/test/data/S58861868/LIB1722.bam +0 -0
- data/test/data/S58861868/LIB1722.sam +1271 -0
- data/test/data/S58861868/S58861868.fa +16 -0
- data/test/data/S58861868/S58861868.fa.fai +1 -0
- data/test/data/S58861868/S58861868.vcf +76 -0
- data/test/data/S58861868/header.txt +9 -0
- data/test/data/S58861868/merged.bam +0 -0
- data/test/data/S58861868/merged_reheader.bam +0 -0
- data/test/data/S58861868/merged_reheader.bam.bai +0 -0
- data/test/data/Test3Aspecific.csv +2 -0
- data/test/data/Test3Aspecific_contigs.fa +6 -0
- data/test/data/bfr_out_test.csv +5 -0
- data/test/data/chr1A_C1145499T/chr1A_C1145499T.csv +1 -0
- data/test/data/chr1A_G540414846C/chr1A_G540414846C.csv +1 -0
- data/test/data/chr1A_G540414846C/chr1A_G540414846C.fa +2 -0
- data/test/data/chr1A_T517634750C/chr1A_T517634750C.csv +1 -0
- data/test/data/chr2D_C112180134A/chr2D_C112180134A.csv +1 -0
- data/test/data/chr4D_C14473543T/chr4D_C14473543T.csv +1 -0
- data/test/data/chr4D_C14473543T/chr4D_C14473543T.fa +2 -0
- data/test/data/headerMergeed.txt +9 -0
- data/test/data/headerS2238015 +1 -0
- data/test/data/mergedLibs.bam +0 -0
- data/test/data/mergedLibsReheader.bam +0 -0
- data/test/data/mergedLibsSorted.bam +0 -0
- data/test/data/mergedLibsSorted.bam.bai +0 -0
- data/test/data/patological_cases5D.csv +1 -0
- data/test/data/primer_3_input_header_test +5 -0
- data/test/data/short_primer_design_test.csv +10 -0
- data/test/data/some_tests/some_tests.csv +201 -0
- data/test/data/test_from_mutant.csv +3 -0
- data/test/data/test_iselect.csv +196 -0
- data/test/data/test_iselect_reference.fa +1868 -0
- data/test/data/test_iselect_reference.fa.fai +934 -0
- data/test/data/test_primer3_error.csv +4 -0
- data/test/data/test_primer3_error_contigs.fa +10 -0
- data/test/test_bfr.rb +135 -0
- data/test/test_blast.rb +47 -0
- data/test/test_exon_container.rb +17 -0
- data/test/test_exonearate.rb +48 -0
- data/test/test_integration.rb +76 -0
- data/test/test_snp_parsing.rb +121 -0
- data/test/test_wrong_selection.sh +5 -0
- metadata +356 -0
metadata
ADDED
@@ -0,0 +1,356 @@
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--- !ruby/object:Gem::Specification
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2
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name: bio-polymarker
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version: !ruby/object:Gem::Version
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version: 1.3.2
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platform: ruby
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authors:
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- Rob Ellis
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autorequire:
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9
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bindir: bin
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cert_chain: []
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11
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date: 2024-09-25 00:00:00.000000000 Z
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dependencies:
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13
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- !ruby/object:Gem::Dependency
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14
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name: bio
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requirement: !ruby/object:Gem::Requirement
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requirements:
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- - ">="
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- !ruby/object:Gem::Version
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version: 1.5.1
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type: :runtime
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prerelease: false
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version_requirements: !ruby/object:Gem::Requirement
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requirements:
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- - ">="
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25
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- !ruby/object:Gem::Version
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26
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version: 1.5.1
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27
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- !ruby/object:Gem::Dependency
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28
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name: bio-samtools-wrapper
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29
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requirement: !ruby/object:Gem::Requirement
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30
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requirements:
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31
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- - ">="
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32
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- !ruby/object:Gem::Version
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33
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version: 2.7.0
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34
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type: :runtime
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35
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prerelease: false
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36
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version_requirements: !ruby/object:Gem::Requirement
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requirements:
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38
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- - ">="
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39
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+
- !ruby/object:Gem::Version
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40
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version: 2.7.0
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41
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- !ruby/object:Gem::Dependency
|
42
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name: descriptive_statistics
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43
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requirement: !ruby/object:Gem::Requirement
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44
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requirements:
|
45
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+
- - ">="
|
46
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+
- !ruby/object:Gem::Version
|
47
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version: '0'
|
48
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type: :runtime
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49
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prerelease: false
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50
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version_requirements: !ruby/object:Gem::Requirement
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51
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requirements:
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52
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+
- - ">="
|
53
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+
- !ruby/object:Gem::Version
|
54
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version: '0'
|
55
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+
- !ruby/object:Gem::Dependency
|
56
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name: systemu
|
57
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requirement: !ruby/object:Gem::Requirement
|
58
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requirements:
|
59
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- - ">="
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60
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- !ruby/object:Gem::Version
|
61
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version: 2.5.2
|
62
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type: :runtime
|
63
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prerelease: false
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64
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version_requirements: !ruby/object:Gem::Requirement
|
65
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requirements:
|
66
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+
- - ">="
|
67
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+
- !ruby/object:Gem::Version
|
68
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version: 2.5.2
|
69
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- !ruby/object:Gem::Dependency
|
70
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name: shoulda
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71
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requirement: !ruby/object:Gem::Requirement
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72
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requirements:
|
73
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- - ">="
|
74
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- !ruby/object:Gem::Version
|
75
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version: '2.10'
|
76
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type: :development
|
77
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prerelease: false
|
78
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version_requirements: !ruby/object:Gem::Requirement
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79
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requirements:
|
80
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- - ">="
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81
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+
- !ruby/object:Gem::Version
|
82
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version: '2.10'
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83
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- !ruby/object:Gem::Dependency
|
84
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name: test-unit
|
85
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requirement: !ruby/object:Gem::Requirement
|
86
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requirements:
|
87
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+
- - ">="
|
88
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+
- !ruby/object:Gem::Version
|
89
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version: '0'
|
90
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type: :development
|
91
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prerelease: false
|
92
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version_requirements: !ruby/object:Gem::Requirement
|
93
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requirements:
|
94
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+
- - ">="
|
95
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+
- !ruby/object:Gem::Version
|
96
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version: '0'
|
97
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+
- !ruby/object:Gem::Dependency
|
98
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name: juwelier
|
99
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requirement: !ruby/object:Gem::Requirement
|
100
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requirements:
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101
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+
- - ">="
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102
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- !ruby/object:Gem::Version
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version: '0'
|
104
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type: :development
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105
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prerelease: false
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106
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version_requirements: !ruby/object:Gem::Requirement
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107
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requirements:
|
108
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- - ">="
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109
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- !ruby/object:Gem::Version
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110
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version: '0'
|
111
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- !ruby/object:Gem::Dependency
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112
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name: sorted_set
|
113
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requirement: !ruby/object:Gem::Requirement
|
114
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requirements:
|
115
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+
- - ">="
|
116
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- !ruby/object:Gem::Version
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version: '0'
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type: :development
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119
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prerelease: false
|
120
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version_requirements: !ruby/object:Gem::Requirement
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requirements:
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- - ">="
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123
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- !ruby/object:Gem::Version
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version: '0'
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description: Repository of tools developed at Crop Genetics in JIC to work with polyploid
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wheat
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email: rob.ellis@jic.ac.uk
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128
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executables:
|
129
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- bfr.rb
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130
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- blast_triads.rb
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131
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- blast_triads_promoters.rb
|
132
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- count_variations.rb
|
133
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- filter_blat_by_target_coverage.rb
|
134
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+
- filter_exonerate_by_identity.rb
|
135
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+
- find_best_blat_hit.rb
|
136
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+
- find_best_exonerate.rb
|
137
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+
- get_longest_hsp_blastx_triads.rb
|
138
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- hexaploid_primers.rb
|
139
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- homokaryot_primers.rb
|
140
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+
- mafft_triads.rb
|
141
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+
- mafft_triads_promoters.rb
|
142
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+
- map_markers_to_contigs.rb
|
143
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+
- marker_to_vcf.rb
|
144
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- markers_in_region.rb
|
145
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- mask_triads.rb
|
146
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- polymarker.rb
|
147
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- polymarker_capillary.rb
|
148
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- polymarker_deletions.rb
|
149
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- snp_position_to_polymarker.rb
|
150
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- snps_between_bams.rb
|
151
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- tag_stats.rb
|
152
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- vcfLineToTable.rb
|
153
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- vcfToPolyMarker.rb
|
154
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extensions: []
|
155
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extra_rdoc_files:
|
156
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- README.md
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157
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files:
|
158
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- ".travis.yml"
|
159
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- Gemfile
|
160
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- README.md
|
161
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- Rakefile
|
162
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- SECURITY.md
|
163
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- VERSION
|
164
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- bin/bfr.rb
|
165
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+
- bin/blast_triads.rb
|
166
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+
- bin/blast_triads_promoters.rb
|
167
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+
- bin/count_variations.rb
|
168
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+
- bin/filter_blat_by_target_coverage.rb
|
169
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+
- bin/filter_exonerate_by_identity.rb
|
170
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+
- bin/find_best_blat_hit.rb
|
171
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+
- bin/find_best_exonerate.rb
|
172
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+
- bin/get_longest_hsp_blastx_triads.rb
|
173
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+
- bin/hexaploid_primers.rb
|
174
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+
- bin/homokaryot_primers.rb
|
175
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+
- bin/mafft_triads.rb
|
176
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- bin/mafft_triads_promoters.rb
|
177
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+
- bin/map_markers_to_contigs.rb
|
178
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+
- bin/marker_to_vcf.rb
|
179
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+
- bin/markers_in_region.rb
|
180
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- bin/mask_triads.rb
|
181
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+
- bin/polymarker.rb
|
182
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+
- bin/polymarker_capillary.rb
|
183
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+
- bin/polymarker_deletions.rb
|
184
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+
- bin/snp_position_to_polymarker.rb
|
185
|
+
- bin/snps_between_bams.rb
|
186
|
+
- bin/tag_stats.rb
|
187
|
+
- bin/vcfLineToTable.rb
|
188
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+
- bin/vcfToPolyMarker.rb
|
189
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+
- bio-polymarker.gemspec
|
190
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|
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|
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|
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|
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|
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|
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|
327
|
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|
328
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- test/test_exon_container.rb
|
329
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|
330
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- test/test_integration.rb
|
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|
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|
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|
+
homepage: https://github.com/cb2e6f/bio-polymarker
|
334
|
+
licenses:
|
335
|
+
- MIT
|
336
|
+
metadata: {}
|
337
|
+
post_install_message:
|
338
|
+
rdoc_options: []
|
339
|
+
require_paths:
|
340
|
+
- lib
|
341
|
+
required_ruby_version: !ruby/object:Gem::Requirement
|
342
|
+
requirements:
|
343
|
+
- - ">="
|
344
|
+
- !ruby/object:Gem::Version
|
345
|
+
version: '0'
|
346
|
+
required_rubygems_version: !ruby/object:Gem::Requirement
|
347
|
+
requirements:
|
348
|
+
- - ">="
|
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|
+
- !ruby/object:Gem::Version
|
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|
+
version: '0'
|
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|
+
requirements: []
|
352
|
+
rubygems_version: 3.5.16
|
353
|
+
signing_key:
|
354
|
+
specification_version: 4
|
355
|
+
summary: Tool to work with polyploids, NGS and molecular biology
|
356
|
+
test_files: []
|