partis-bcr 1.0.8__py3-none-any.whl → 1.0.9.post1.dev1__py3-none-any.whl

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Files changed (156) hide show
  1. packages/ham/bcrham +0 -0
  2. packages/ig-sw/src/ig_align/ig-sw +0 -0
  3. {partis_bcr-1.0.8.dist-info → partis_bcr-1.0.9.post1.dev1.dist-info}/METADATA +1 -1
  4. {partis_bcr-1.0.8.dist-info → partis_bcr-1.0.9.post1.dev1.dist-info}/RECORD +155 -73
  5. test/new-results/get-selection-metrics-new-simu.yaml +1 -0
  6. test/new-results/test.log +12 -16
  7. test/paired/new-results/get-selection-metrics-new-simu-chosen-abs.csv +8 -8
  8. test/paired/new-results/partition-new-simu/fasttree/iclust-0/fasttree.out +1 -1
  9. test/paired/new-results/partition-new-simu/fasttree/iclust-0/log +8 -8
  10. test/paired/new-results/partition-new-simu/fasttree/iclust-1/fasttree.out +1 -1
  11. test/paired/new-results/partition-new-simu/fasttree/iclust-1/log +7 -7
  12. test/paired/new-results/partition-new-simu/fasttree/iclust-2/fasttree.out +1 -1
  13. test/paired/new-results/partition-new-simu/fasttree/iclust-2/log +9 -9
  14. test/paired/new-results/partition-new-simu/igh+igk/partition-igh/fasttree/iclust-0/fasttree.out +1 -1
  15. test/paired/new-results/partition-new-simu/igh+igk/partition-igh/fasttree/iclust-0/log +8 -8
  16. test/paired/new-results/partition-new-simu/igh+igk/partition-igh/fasttree/iclust-1/fasttree.out +1 -1
  17. test/paired/new-results/partition-new-simu/igh+igk/partition-igh/fasttree/iclust-1/log +9 -9
  18. test/paired/new-results/partition-new-simu/igh+igk/partition-igh-selection-metrics.yaml +1 -1
  19. test/paired/new-results/partition-new-simu/igh+igk/partition-igk/fasttree/iclust-0/fasttree.out +1 -1
  20. test/paired/new-results/partition-new-simu/igh+igk/partition-igk/fasttree/iclust-0/log +8 -8
  21. test/paired/new-results/partition-new-simu/igh+igk/partition-igk/fasttree/iclust-1/fasttree.out +1 -1
  22. test/paired/new-results/partition-new-simu/igh+igk/partition-igk/fasttree/iclust-1/log +4 -4
  23. test/paired/new-results/partition-new-simu/igh+igk/partition-igk-selection-metrics.yaml +1 -1
  24. test/paired/new-results/partition-new-simu/igh+igl/partition-igh/fasttree/iclust-0/fasttree.out +1 -1
  25. test/paired/new-results/partition-new-simu/igh+igl/partition-igh/fasttree/iclust-0/log +9 -9
  26. test/paired/new-results/partition-new-simu/igh+igl/partition-igh-selection-metrics.yaml +1 -1
  27. test/paired/new-results/partition-new-simu/igh+igl/partition-igl/fasttree/iclust-0/fasttree.out +1 -1
  28. test/paired/new-results/partition-new-simu/igh+igl/partition-igl/fasttree/iclust-0/log +9 -9
  29. test/paired/new-results/partition-new-simu/igh+igl/partition-igl/fasttree/iclust-1/log +3 -3
  30. test/paired/new-results/partition-new-simu/igh+igl/partition-igl-selection-metrics.yaml +1 -1
  31. test/paired/new-results/partition-new-simu/selection-metrics.yaml +1 -1
  32. test/paired/new-results/partition-new-simu/single-chain/partition-igh.yaml +1 -1
  33. test/paired/new-results/partition-new-simu-annotation-performance/plots/flcount-matrix.svg +107 -107
  34. test/paired/new-results/partition-new-simu-annotation-performance/plots/func-non-func-per-drop-log.svg +83 -83
  35. test/paired/new-results/partition-new-simu-annotation-performance/plots/func-non-func-per-drop.svg +61 -61
  36. test/paired/new-results/partition-new-simu-annotation-performance/plots/paired-seqs-per-seq-after.svg +18 -18
  37. test/paired/new-results/partition-new-simu-annotation-performance/plots/paired-seqs-per-seq-before.svg +24 -24
  38. test/paired/new-results/partition-new-simu-annotation-performance/plots/pseq-matrix.svg +35 -35
  39. test/paired/new-results/partition-new-simu-annotation-performance/plots/seqs-per-droplet.svg +22 -22
  40. test/paired/new-results/partition-new-simu-annotation-performance/plots/true-pair-clean-performance-correct-family.svg +45 -45
  41. test/paired/new-results/partition-new-simu-annotation-performance/plots/true-pair-clean-performance-correct.svg +45 -45
  42. test/paired/new-results/partition-new-simu-annotation-performance/plots/true-pair-clean-performance-mispaired.svg +45 -45
  43. test/paired/new-results/partition-new-simu-annotation-performance/plots/true-pair-clean-performance-multiple.svg +15 -15
  44. test/paired/new-results/partition-new-simu-annotation-performance/plots/true-pair-clean-performance-near-family.svg +15 -15
  45. test/paired/new-results/partition-new-simu-annotation-performance/plots/true-pair-clean-performance-total.svg +47 -47
  46. test/paired/new-results/partition-new-simu-annotation-performance/plots/true-pair-clean-performance-unpaired.svg +48 -48
  47. test/paired/new-results/partition-new-simu-annotation-performance/plots/true-pair-clean-performance.svg +27 -27
  48. test/paired/new-results/run-times.csv +6 -6
  49. test/paired/new-results/subset-partition-new-simu/isub-0/partition.log +86 -102
  50. test/paired/new-results/subset-partition-new-simu/isub-1/igh+igk/partition-igh.yaml +1 -1
  51. test/paired/new-results/subset-partition-new-simu/isub-1/partition-igh.yaml +1 -1
  52. test/paired/new-results/subset-partition-new-simu/isub-1/partition.log +84 -100
  53. test/paired/new-results/subset-partition-new-simu/isub-1/single-chain/partition-igh.yaml +1 -1
  54. test/paired/new-results/subset-partition-new-simu/merged-partition.log +50 -54
  55. test/paired/new-results/subset-partition-new-simu/merged-subsets/igh+igk/partition-igh.yaml +1 -1
  56. test/paired/new-results/subset-partition-new-simu/merged-subsets/parameters/igh/sw-cache.yaml +1 -1
  57. test/paired/new-results/subset-partition-new-simu/merged-subsets/parameters/igk/sw-cache.yaml +1 -1
  58. test/paired/new-results/subset-partition-new-simu/merged-subsets/parameters/igl/sw-cache.yaml +1 -1
  59. test/paired/new-results/subset-partition-new-simu/merged-subsets/partition-igh.yaml +1 -1
  60. test/paired/new-results/test.log +203 -236
  61. test/ref-results/partition-new-simu/fasttree/iclust-0/fasttree.out +1 -0
  62. test/ref-results/partition-new-simu/fasttree/iclust-0/input-seqs.fa +24 -0
  63. test/ref-results/partition-new-simu/fasttree/iclust-0/log +23 -0
  64. test/ref-results/partition-new-simu/fasttree/iclust-1/fasttree.out +1 -0
  65. test/ref-results/partition-new-simu/fasttree/iclust-1/input-seqs.fa +16 -0
  66. test/ref-results/partition-new-simu/fasttree/iclust-1/log +23 -0
  67. test/ref-results/partition-new-simu/fasttree/iclust-2/fasttree.out +1 -0
  68. test/ref-results/partition-new-simu/fasttree/iclust-2/input-seqs.fa +16 -0
  69. test/ref-results/partition-new-simu/fasttree/iclust-2/log +22 -0
  70. test/ref-results/partition-new-simu/iqtree/iclust-0/input-seqs.fa +24 -0
  71. test/ref-results/partition-new-simu/iqtree/iclust-0/log +430 -0
  72. test/ref-results/partition-new-simu/iqtree/iclust-0/out.bionj +1 -0
  73. test/ref-results/partition-new-simu/iqtree/iclust-0/out.ckp.gz +0 -0
  74. test/ref-results/partition-new-simu/iqtree/iclust-0/out.iqtree +282 -0
  75. test/ref-results/partition-new-simu/iqtree/iclust-0/out.log +429 -0
  76. test/ref-results/partition-new-simu/iqtree/iclust-0/out.mldist +13 -0
  77. test/ref-results/partition-new-simu/iqtree/iclust-0/out.model.gz +0 -0
  78. test/ref-results/partition-new-simu/iqtree/iclust-0/out.state +3529 -0
  79. test/ref-results/partition-new-simu/iqtree/iclust-0/out.treefile +1 -0
  80. test/ref-results/partition-new-simu/iqtree/iclust-1/input-seqs.fa +16 -0
  81. test/ref-results/partition-new-simu/iqtree/iclust-1/log +373 -0
  82. test/ref-results/partition-new-simu/iqtree/iclust-1/out.bionj +1 -0
  83. test/ref-results/partition-new-simu/iqtree/iclust-1/out.ckp.gz +0 -0
  84. test/ref-results/partition-new-simu/iqtree/iclust-1/out.iqtree +279 -0
  85. test/ref-results/partition-new-simu/iqtree/iclust-1/out.log +372 -0
  86. test/ref-results/partition-new-simu/iqtree/iclust-1/out.mldist +9 -0
  87. test/ref-results/partition-new-simu/iqtree/iclust-1/out.model.gz +0 -0
  88. test/ref-results/partition-new-simu/iqtree/iclust-1/out.state +2229 -0
  89. test/ref-results/partition-new-simu/iqtree/iclust-1/out.treefile +1 -0
  90. test/ref-results/partition-new-simu/iqtree/iclust-2/input-seqs.fa +16 -0
  91. test/ref-results/partition-new-simu/iqtree/iclust-2/log +375 -0
  92. test/ref-results/partition-new-simu/iqtree/iclust-2/out.bionj +1 -0
  93. test/ref-results/partition-new-simu/iqtree/iclust-2/out.ckp.gz +0 -0
  94. test/ref-results/partition-new-simu/iqtree/iclust-2/out.iqtree +274 -0
  95. test/ref-results/partition-new-simu/iqtree/iclust-2/out.log +374 -0
  96. test/ref-results/partition-new-simu/iqtree/iclust-2/out.mldist +9 -0
  97. test/ref-results/partition-new-simu/iqtree/iclust-2/out.model.gz +0 -0
  98. test/ref-results/partition-new-simu/iqtree/iclust-2/out.state +2283 -0
  99. test/ref-results/partition-new-simu/iqtree/iclust-2/out.treefile +1 -0
  100. test/ref-results/partition-new-simu/iqtree-annotations.yaml +1 -0
  101. test/ref-results/partition-new-simu/raxml/iclust-0/input-seqs.fa +24 -0
  102. test/ref-results/partition-new-simu/raxml/iclust-0/input-seqs.fa.raxml.ancestralProbs +3461 -0
  103. test/ref-results/partition-new-simu/raxml/iclust-0/input-seqs.fa.raxml.ancestralStates +10 -0
  104. test/ref-results/partition-new-simu/raxml/iclust-0/input-seqs.fa.raxml.ancestralTree +1 -0
  105. test/ref-results/partition-new-simu/raxml/iclust-0/input-seqs.fa.raxml.bestModel +1 -0
  106. test/ref-results/partition-new-simu/raxml/iclust-0/input-seqs.fa.raxml.bestTree +1 -0
  107. test/ref-results/partition-new-simu/raxml/iclust-0/input-seqs.fa.raxml.bestTreeCollapsed +1 -0
  108. test/ref-results/partition-new-simu/raxml/iclust-0/input-seqs.fa.raxml.log +216 -0
  109. test/ref-results/partition-new-simu/raxml/iclust-0/input-seqs.fa.raxml.mlTrees +20 -0
  110. test/ref-results/partition-new-simu/raxml/iclust-0/input-seqs.fa.raxml.rba +0 -0
  111. test/ref-results/partition-new-simu/raxml/iclust-0/input-seqs.fa.raxml.reduced.phy +9 -0
  112. test/ref-results/partition-new-simu/raxml/iclust-0/input-seqs.fa.raxml.startTree +20 -0
  113. test/ref-results/partition-new-simu/raxml/iclust-0/log +454 -0
  114. test/ref-results/partition-new-simu/raxml/iclust-0/run.sh +3 -0
  115. test/ref-results/partition-new-simu/raxml/iclust-1/input-seqs.fa +16 -0
  116. test/ref-results/partition-new-simu/raxml/iclust-1/input-seqs.fa.raxml.ancestralProbs +2203 -0
  117. test/ref-results/partition-new-simu/raxml/iclust-1/input-seqs.fa.raxml.ancestralStates +6 -0
  118. test/ref-results/partition-new-simu/raxml/iclust-1/input-seqs.fa.raxml.ancestralTree +1 -0
  119. test/ref-results/partition-new-simu/raxml/iclust-1/input-seqs.fa.raxml.bestModel +1 -0
  120. test/ref-results/partition-new-simu/raxml/iclust-1/input-seqs.fa.raxml.bestTree +1 -0
  121. test/ref-results/partition-new-simu/raxml/iclust-1/input-seqs.fa.raxml.bestTreeCollapsed +1 -0
  122. test/ref-results/partition-new-simu/raxml/iclust-1/input-seqs.fa.raxml.log +217 -0
  123. test/ref-results/partition-new-simu/raxml/iclust-1/input-seqs.fa.raxml.mlTrees +20 -0
  124. test/ref-results/partition-new-simu/raxml/iclust-1/input-seqs.fa.raxml.rba +0 -0
  125. test/ref-results/partition-new-simu/raxml/iclust-1/input-seqs.fa.raxml.reduced.phy +4 -0
  126. test/ref-results/partition-new-simu/raxml/iclust-1/input-seqs.fa.raxml.startTree +20 -0
  127. test/ref-results/partition-new-simu/raxml/iclust-1/log +440 -0
  128. test/ref-results/partition-new-simu/raxml/iclust-1/run.sh +3 -0
  129. test/ref-results/partition-new-simu/raxml/iclust-2/input-seqs.fa +16 -0
  130. test/ref-results/partition-new-simu/raxml/iclust-2/input-seqs.fa.raxml.ancestralProbs +2275 -0
  131. test/ref-results/partition-new-simu/raxml/iclust-2/input-seqs.fa.raxml.ancestralStates +6 -0
  132. test/ref-results/partition-new-simu/raxml/iclust-2/input-seqs.fa.raxml.ancestralTree +1 -0
  133. test/ref-results/partition-new-simu/raxml/iclust-2/input-seqs.fa.raxml.bestModel +1 -0
  134. test/ref-results/partition-new-simu/raxml/iclust-2/input-seqs.fa.raxml.bestTree +1 -0
  135. test/ref-results/partition-new-simu/raxml/iclust-2/input-seqs.fa.raxml.bestTreeCollapsed +1 -0
  136. test/ref-results/partition-new-simu/raxml/iclust-2/input-seqs.fa.raxml.log +207 -0
  137. test/ref-results/partition-new-simu/raxml/iclust-2/input-seqs.fa.raxml.mlTrees +20 -0
  138. test/ref-results/partition-new-simu/raxml/iclust-2/input-seqs.fa.raxml.rba +0 -0
  139. test/ref-results/partition-new-simu/raxml/iclust-2/input-seqs.fa.raxml.startTree +20 -0
  140. test/ref-results/partition-new-simu/raxml/iclust-2/log +420 -0
  141. test/ref-results/partition-new-simu/raxml/iclust-2/run.sh +3 -0
  142. test/ref-results/partition-new-simu/raxml-annotations.yaml +1 -0
  143. bin/FastTree-macos +0 -0
  144. {partis_bcr-1.0.8.data → partis_bcr-1.0.9.post1.dev1.data}/scripts/cf-alleles.py +0 -0
  145. {partis_bcr-1.0.8.data → partis_bcr-1.0.9.post1.dev1.data}/scripts/cf-germlines.py +0 -0
  146. {partis_bcr-1.0.8.data → partis_bcr-1.0.9.post1.dev1.data}/scripts/compare-plotdirs.py +0 -0
  147. {partis_bcr-1.0.8.data → partis_bcr-1.0.9.post1.dev1.data}/scripts/extract-pairing-info.py +0 -0
  148. {partis_bcr-1.0.8.data → partis_bcr-1.0.9.post1.dev1.data}/scripts/gctree-run.py +0 -0
  149. {partis_bcr-1.0.8.data → partis_bcr-1.0.9.post1.dev1.data}/scripts/get-naive-probabilities.py +0 -0
  150. {partis_bcr-1.0.8.data → partis_bcr-1.0.9.post1.dev1.data}/scripts/parse-output.py +0 -0
  151. {partis_bcr-1.0.8.data → partis_bcr-1.0.9.post1.dev1.data}/scripts/partis-test.py +0 -0
  152. {partis_bcr-1.0.8.data → partis_bcr-1.0.9.post1.dev1.data}/scripts/split-loci.py +0 -0
  153. {partis_bcr-1.0.8.dist-info → partis_bcr-1.0.9.post1.dev1.dist-info}/WHEEL +0 -0
  154. {partis_bcr-1.0.8.dist-info → partis_bcr-1.0.9.post1.dev1.dist-info}/entry_points.txt +0 -0
  155. {partis_bcr-1.0.8.dist-info → partis_bcr-1.0.9.post1.dev1.dist-info}/licenses/COPYING +0 -0
  156. {partis_bcr-1.0.8.dist-info → partis_bcr-1.0.9.post1.dev1.dist-info}/top_level.txt +0 -0
test/paired/new-results/subset-partition-new-simu/merged-subsets/partition-igh.yaml CHANGED
@@ -1 +1 @@
1
- {"version-info": {"partis-yaml": 0.1, "partis-git": ""}, "germline-info": {"locus": "igh", "functionalities": {}, "seqs": {"v": {"IGHV1-2*02": "CAGGTGCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGGCCTCAGTGAAGGTCTCCTGCAAGGCTTCTGGATACACCTTCACCGGCTACTATATGCACTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGATGGATCAACCCTAACAGTGGTGGCACAAACTATGCACAGAAGTTTCAGGGCAGGGTCACCATGACCAGGGACACGTCCATCAGCACAGCCTACATGGAGCTGAGCAGGCTGAGATCTGACGACACGGCCGTGTATTACTGTGCGAGAGA", "IGHV1-69*04": "CAGGTCCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGTCCTCGGTGAAGGTCTCCTGCAAGGCTTCTGGAGGCACCTTCAGCAGCTATGCTATCAGCTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGAAGGATCATCCCTATCCTTGGTATAGCAAACTACGCACAGAAGTTCCAGGGCAGAGTCACGATTACCGCGGACAAATCCACGAGCACAGCCTACATGGAGCTGAGCAGCCTGAGATCTGAGGACACGGCCGTGTATTACTGTGCGAGAGA", "IGHV2-70*01": "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATAC", "IGHV3-33*01": "CAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGA", "IGHV3-7*01": "GAGGTGCAGCTGGTGGAGTCTGGGGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGACTCTCCTGTGCAGCCTCTGGATTCACCTTTAGTAGCTATTGGATGAGCTGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAGTGGGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGGACTCTGTGAAGGGCCGATTCACCATCTCCAGAGACAACGCCAAGAACTCACTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGA", "IGHV4-39*01": "CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGAAGCCTTCGGAGACCCTGTCCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACTGGGGCTGGATCCGCCAGCCCCCAGGGAAGGGGCTGGAGTGGATTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCCGTCCCTCAAGAGTCGAGTCACCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGCTCTGTGACCGCCGCAGACACGGCTGTGTATTACTGTGCGAGACA"}, "d": {"IGHD1-1*01": "GGTACAACTGGAACGAC", "IGHD1-14*01": "GGTATAACCGGAACCAC", "IGHD1-26*01": "GGTATAGTGGGAGCTACTAC", "IGHD2-21*01": "AGCATATTGTGGTGGTGATTGCTATTCC", "IGHD3-10*03": "GTATTACTATGGTTCAGGGAGTTATTATAAC", "IGHD3-16*03": "GTATTATGATTACATTTGGGGGAGTTATCGTTATACC", "IGHD3-3*01": "GTATTACGATTTTTGGAGTGGTTATTATACC", "IGHD6-19*01": "GGGTATAGCAGTGGCTGGTAC", "IGHD6-6*01": "GAGTATAGCAGCTCGTCC", "IGHD2-15*01": "AGGATATTGTAGTGGTGGTAGCTGCTACTCC", "IGHD2-2*01": "AGGATATTGTAGTAGTACCAGCTGCTATGCC", "IGHD2-8*01": "AGGATATTGTACTAATGGTGTATGCTATACC", "IGHD2-8*02": "AGGATATTGTACTGGTGGTGTATGCTATACC", "IGHD3-9*01": "GTATTACGATATTTTGACTGGTTATTATAAC", "IGHD7-27*01": "CTAACTGGGGA"}, "j": {"IGHJ3*02": "TGATGCTTTTGATATCTGGGGCCAAGGGACAATGGTCACCGTCTCTTCAG", "IGHJ4*02": "ACTACTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "IGHJ5*02": "ACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "IGHJ6*02": "ATTACTACTACTACTACGGTATGGACGTCTGGGGCCAAGGGACCACGGTCACCGTCTCCTCAG"}}, "cyst-positions": {"IGHV1-69*04": 285, "IGHV1-2*02": 285, "IGHV3-33*01": 285, "IGHV2-70*01": 288, "IGHV3-7*01": 285, "IGHV4-39*01": 288}, "tryp-positions": {"IGHJ4*02": 14, "IGHJ3*02": 16, "IGHJ6*02": 29, "IGHJ5*02": 17}}, "partitions": [{"logprob": 0.0, "n_clusters": 27, "n_procs": 1, "partition": [["28f6e090f2-igh", "584ba32878-igh"], ["3a07b6f0a9-igh", "f3509e0ef3-igh"], ["4f03967793-igh", "6577576bb8-igh", "6cf028b770-igh", "c0fcfe005f-igh", "c2cc9da0c3-igh"], ["7c67587674-igh", "cdae60eacc-igh"], ["8b9ef6b10e-igh"], ["a4b090d0be-igh", "e6fa048856-igh"], ["bb82ebe094-igh"], ["be186138e0-igh"], ["09f5010bd3-igh", "eee6809ad6-igh"], ["e11acbe3ab-igh", "eee2c7797d-igh"], ["276733008f-igh"], ["28ce45b82a-igh"], ["3542bd38d8-igh"], ["35fc655801-igh", "7ba384a461-igh", "7d4166ae48-igh"], ["3c5f4c778a-igh"], ["453132f3ab-igh", "7334912e1e-igh", "f094dfd68a-igh", "b997fa9304-igh"], ["665985d2d1-igh", "d1ee7f9ce6-igh"], ["789d880ef2-igh"], ["b9148494e2-igh"], ["253ca59333-igh", "8d79fca804-igh", "a2238f4e9a-igh", "a3baa83300-igh"], ["7588f09c07-igh", "aa25e6c0ce-igh"], ["b739ce37b7-igh"], ["0eb272ee70-igh", "4d37fe487e-igh", "b02ee7754a-igh", "b1e56e40a1-igh", "ddcf0ca433-igh", "9ed10b6475-igh"], ["14195e4958-igh"], ["21cea6e4d0-igh", "57537e5f22-igh"], ["cfe3b29587-igh"], ["bc11af4843-igh"]]}], "events": [{"has_shm_indels": [false, false], "qr_gap_seqs": ["", ""], "gl_gap_seqs": ["", ""], "indel_reversed_seqs": ["", ""], "unique_ids": ["28f6e090f2-igh", "584ba32878-igh"], "invalid": false, "v_gene": "IGHV1-2*02", "d_gene": "IGHD6-6*01", "j_gene": "IGHJ3*02", "cdr3_length": 63, "mut_freqs": [0.0, 0.0], "n_mutations": [0, 0], "input_seqs": ["NNNCAGGTGCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGGCCTCAGTGAAGGTCTCCTGCAAGGCTTCTGGATACACCTTCACCGGCTACTATATGCACTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGATGGATCAACCCTAACAGTGGTGGCACAAACTATGCACAGAAGTTTCAGGGCAGGGTCACCATGACCAGGGACACGTCCATCAGCACAGCCTACATGGAGCTGAGCAGGCTGAGATCTGACGACACGGCCGTGTATTACTGTGCGAGAACCGGACTGCTCTGTATAGCAGCTCGTCCCGATGGTGATGCTTTTGATATCTGGGGCCAAGGGACAATGGTCACCGTCTCTTCAG", "NNNCAGGTGCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGGCCTCAGTGAAGGTCTCCTGCAAGGCTTCTGGATACACCTTCACCGGCTACTATATGCACTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGATGGATCAACCCTAACAGTGGTGGCACAAACTATGCACAGAAGTTTCAGGGCAGGGTCACCATGACCAGGGACACGTCCATCAGCACAGCCTACATGGAGCTGAGCAGGCTGAGATCTGACGACACGGCCGTGTATTACTGTGCGAGAACCGGACTGCTCTGTATAGCAGCTCGTCCCGATGGTGATGCTTTTGATATCTGGGGCCAAGGGACAATGGTCACCGTCTCTTCAG"], "naive_seq": "NNNCAGGTGCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGGCCTCAGTGAAGGTCTCCTGCAAGGCTTCTGGATACACCTTCACCGGCTACTATATGCACTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGATGGATCAACCCTAACAGTGGTGGCACAAACTATGCACAGAAGTTTCAGGGCAGGGTCACCATGACCAGGGACACGTCCATCAGCACAGCCTACATGGAGCTGAGCAGGCTGAGATCTGACGACACGGCCGTGTATTACTGTGCGAGAACCGGACTGCTCTGTATAGCAGCTCGTCCCGATGGTGATGCTTTTGATATCTGGGGCCAAGGGACAATGGTCACCGTCTCTTCAG", "duplicates": [[], []], "leader_seqs": ["", ""], "c_gene_seqs": ["", ""], "v_per_gene_support": {"IGHV1-2*02": 1.0}, "d_per_gene_support": {"IGHD6-6*01": 0.9999998701800279, "IGHD6-19*01": 1.2981997812807179e-07}, "j_per_gene_support": {"IGHJ3*02": 1.0}, "v_3p_del": 2, "d_5p_del": 2, "d_3p_del": 0, "j_5p_del": 0, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "ACCGGACTGCTCT", "dj_insertion": "CGATGG", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false, false], "in_frames": [true, true], "stops": [false, false], "paired-uids": [["28f6e090f2-igk"], []], "loci": ["igh", "igh"], "codon_positions": {"v": 288, "j": 348}}, {"has_shm_indels": [false, false], "qr_gap_seqs": ["", ""], "gl_gap_seqs": ["", ""], "indel_reversed_seqs": ["", ""], "unique_ids": ["3a07b6f0a9-igh", "f3509e0ef3-igh"], "invalid": false, "v_gene": "IGHV3-33*01", "d_gene": "IGHD1-14*01", "j_gene": "IGHJ6*02", "cdr3_length": 54, "mut_freqs": [0.02702702702702703, 0.02972972972972973], "n_mutations": [10, 11], "input_seqs": ["NNNCAGGTGCAGCTGGTGGAATCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACTCTGCTGTGCAGCGTCTGGATTCACCTTCAGTAGGTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGAGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGTTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGTCACGGCTGTGTATTACTGTGCGAGAGAGCCGGAACCGGAACAAATAGTTGCCTACGGTATGGACGTCTGGGGCCAAGGGACCACGGTCACCGTCTCCTCAG", "NNNCTAGTTCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCTGAATTCACCTTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATCTGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGGGGACACGGCTGTGTATTACTGTGCGAGAGAGCCGACACAGGAACCACGAGTTTGCTACGATATGGACGTCTGGGGCCAAGGGACCACGGTCACCGTCTCCTCAG"], "naive_seq": "NNNCAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGAGCCGGAACCGGAACCACGAGTTGGCTACGGTATGGACGTCTGGGGCCAAGGGACCACGGTCACCGTCTCCTCAG", "duplicates": [[], []], "leader_seqs": ["", ""], "c_gene_seqs": ["", ""], "v_per_gene_support": {"IGHV3-33*01": 1.0}, "d_per_gene_support": {"IGHD1-14*01": 0.9999448576836041, "IGHD1-1*01": 5.514231639909855e-05}, "j_per_gene_support": {"IGHJ6*02": 1.0}, "v_3p_del": 0, "d_5p_del": 5, "d_3p_del": 0, "j_5p_del": 13, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "GCCGG", "dj_insertion": "GAGTTGG", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false, false], "in_frames": [true, true], "stops": [false, false], "paired-uids": [["3a07b6f0a9-igk"], ["f3509e0ef3-igk"]], "loci": ["igh", "igh"], "codon_positions": {"v": 288, "j": 339}}, {"has_shm_indels": [false, true, false, false, false], "qr_gap_seqs": ["", "NNNCAGGTGTAGCTGATGGTGTCTGGGGGAGGCGTGGTCCAGCCTAGGAGGTCCCTGAGACTGACTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGCTATGCCATGCACTGGGTCCGCCAGGCACCCGCCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTATTATATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACCCGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGAATTACTGTGCGAGAGAGGCTGGAGGCGATTTGTGGAATGGTATTTTCGGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "", "", ""], "gl_gap_seqs": ["", "NNNCAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACT..CTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGAGGGCGGGGGCGATTTTTGGAGTGGTTATTATGGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "", "", ""], "indel_reversed_seqs": ["", "NNNCAGGTGTAGCTGATGGTGTCTGGGGGAGGCGTGGTCCAGCCTAGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGCTATGCCATGCACTGGGTCCGCCAGGCACCCGCCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTATTATATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACCCGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGAATTACTGTGCGAGAGAGGCTGGAGGCGATTTGTGGAATGGTATTTTCGGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "", "", ""], "unique_ids": ["4f03967793-igh", "6577576bb8-igh", "6cf028b770-igh", "c0fcfe005f-igh", "c2cc9da0c3-igh"], "invalid": false, "v_gene": "IGHV3-33*01", "d_gene": "IGHD3-3*01", "j_gene": "IGHJ5*02", "cdr3_length": 66, "mut_freqs": [0.060209424083769635, 0.0549738219895288, 0.06806282722513089, 0.034031413612565446, 0.06282722513089005], "n_mutations": [23, 21, 26, 13, 24], "input_seqs": ["NNNCAGGTGCAGCTGATGGTGTCTGGGGGAGGCGGGGTCCAGCCGAGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCGGGATTCACCTTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCACCCGCCAAGGGGCTGGAGTGGGTGGCAATTATATGGTATGATGGAAGTAACAAATACTATGCAGACTCCGTGAAGGGCTGATTCACCATCTCCAGAGACAATTCCAAGAACCCGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGAATTACTGTGCGAGAGAGGGTGGAGGGGATCTCTGGACTGGTCTTTATGGGAACAACTGGTTCGACCCCTGGGGACAGGGAACCCTGGTCACCGTCTCCTCAG", "NNNCAGGTGTAGCTGATGGTGTCTGGGGGAGGCGTGGTCCAGCCTAGGAGGTCCCTGAGACTGACTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGCTATGCCATGCACTGGGTCCGCCAGGCACCCGCCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTATTATATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACCCGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGAATTACTGTGCGAGAGAGGCTGGAGGCGATTTGTGGAATGGTATTTTCGGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "NNNCAGGCGCAGCGGATGGAGTCTGGGGGAGGCGTGGTCCAGCCTAGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCAGGATTCACCTTCAGTAGCTATGGCATGCACCGGGTCCGCCAGGCACCCGCCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATCTTGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACCCGCTGTATCTGCAAATGACAAGCCTGAGAGCCGAGGACACGGATGTGAATTACTGTGCGAGAGATACTGGCGGCGATTTTTCGAATGGCCTTTATGGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "NNNCAGGTGCAGCTGGCGGAGTCTGGGGGAGGCGTGGTCCACCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCATCTGGATTCACCGTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTGCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGAATTACTGTGCGAGAGAGGCCGGGTGAGATTTTGGGTTTGGTTACTATGGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "NNNCAGGTGCAGCTGGTGGGGTCTGGGGGAGGCGTGGTCCAGCCTGGTAGGTCCCTGAGACTCTCCTGTGCAGCGTCTGGATTGACCTTATGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGAGTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAATTGAACAGCTTGAGAGCCGAGGAGACGGCTGTGAATTACTGTCCGAGAGAGGGTGGATTCGAATTATGGATTTGATAGTATGGTACCAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAT"], "naive_seq": "NNNCAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGAGGGCGGGGGCGATTTTTGGAGTGGTTATTATGGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[], [], [], [], []], "leader_seqs": ["", "", "", "", ""], "c_gene_seqs": ["", "", "", "", ""], "v_per_gene_support": {"IGHV3-33*01": 1.0}, "d_per_gene_support": {"IGHD3-3*01": 0.9999999999999716, "IGHD6-19*01": 3.4320278689515095e-14, "IGHD2-21*01": 2.3442754905591374e-15, "IGHD3-10*03": 1.2604117936226715e-16}, "j_per_gene_support": {"IGHJ5*02": 1.0}, "v_3p_del": 0, "d_5p_del": 6, "d_3p_del": 3, "j_5p_del": 0, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "GGGCGGGGG", "dj_insertion": "GGGA", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false, false, false, false, false], "in_frames": [true, false, true, true, true], "stops": [true, true, false, true, true], "paired-uids": [["4f03967793-igk"], ["6577576bb8-igk"], ["6cf028b770-igk"], ["c0fcfe005f-igk"], ["c2cc9da0c3-igk"]], "loci": ["igh", "igh", "igh", "igh", "igh"], "codon_positions": {"v": 288, "j": 351}}, {"has_shm_indels": [false, false], "qr_gap_seqs": ["", ""], "gl_gap_seqs": ["", ""], "indel_reversed_seqs": ["", ""], "unique_ids": ["7c67587674-igh", "cdae60eacc-igh"], "invalid": false, "v_gene": "IGHV3-33*01", "d_gene": "IGHD3-3*01", "j_gene": "IGHJ5*02", "cdr3_length": 66, "mut_freqs": [0.031413612565445025, 0.031413612565445025], "n_mutations": [12, 12], "input_seqs": ["NNNCGGGTGCAGCTGATGGAGTCTGGGGGAGGCGTGGTACAGCCTGGGAGGTCCCTGAGACTCTCCTATGCAGCGTCTGGATTCACCTTCAGTAGCTATGGCATGCACTGGGTCGGCCAGGCTCCCGCCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATGCGCCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGAATTACTGTGCGAGAGAGGCTGGATGCGTTTTTTGGAATGGTCCGTCAAGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "NNNCGGGTGCAGCTGATGGAGTCTGGGGGAGGCGTGGTACAGCCTGGGAGGTCCCTGAGACTCTCCTATGCAGCGTCTGGATTCACCTTCAGTAGCTATGGCATGCACTGGGTCGGCCAGGCTCCCGCCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATGCGCCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGAATTACTGTGCGAGAGAGGCTGGATGCGTTTTTTGGAATGGTCCGTCAAGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG"], "naive_seq": "NNNCAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGAGGCTGGATGCGATTTTTGGAGTGGTCCGTCAAGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[], []], "leader_seqs": ["", ""], "c_gene_seqs": ["", ""], "v_per_gene_support": {"IGHV3-33*01": 1.0}, "d_per_gene_support": {"IGHD3-3*01": 0.9998765244606097, "IGHD6-19*01": 0.000123475539386214}, "j_per_gene_support": {"IGHJ5*02": 1.0}, "v_3p_del": 0, "d_5p_del": 6, "d_3p_del": 9, "j_5p_del": 0, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "GGCTGGATG", "dj_insertion": "CCGTCAAGGA", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false, false], "in_frames": [true, true], "stops": [false, false], "paired-uids": [["7c67587674-igk"], ["cdae60eacc-igk"]], "loci": ["igh", "igh"], "codon_positions": {"v": 288, "j": 351}}, {"has_shm_indels": [false], "qr_gap_seqs": [""], "gl_gap_seqs": [""], "indel_reversed_seqs": [""], "unique_ids": ["8b9ef6b10e-igh"], "invalid": false, "v_gene": "IGHV3-7*01", "d_gene": "IGHD6-6*01", "j_gene": "IGHJ4*02", "cdr3_length": 48, "mut_freqs": [0.04945054945054945], "n_mutations": [18], "input_seqs": ["NNNTAGCTGCAGCTGGCGGAGTCTGGGGGAGGCTTGGTCGAGTCTGGGGGGTCCATGAGACTCTCCTGTGCAGCCTCTGGATTCACCTTTAGTAGTTTTTGGATGAGCTGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAGTGGGTGGCCAACATTAAGCAAGATGGAAGTGAGAAATTCTATGTGGACTCTGTGAAGGGCCGATTCACCATCTCCAGAGACAACGCCAAGAACTAACTGTATCTGCAAATGAACACCCTGAAAGCCGAGGACACGGCTGTGTATTATTGTGCGAGAGAGCGTTCAGCTCGGGGACATGAGCGGGCTGACTAGTGGGGCCAGGGAATCCTTGTCACCGTCTCCACAG"], "naive_seq": "NNNGAGGTGCAGCTGGTGGAGTCTGGGGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGACTCTCCTGTGCAGCCTCTGGATTCACCTTTAGTAGCTATTGGATGAGCTGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAGTGGGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGGACTCTGTGAAGGGCCGATTCACCATCTCCAGAGACAACGCCAAGAACTCACTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGAGCGTTCAGCTCGGGGACATGAGCGGGCTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV3-7*01": 1.0}, "d_per_gene_support": {"IGHD6-6*01": 0.9566124162807413, "IGHD3-10*03": 0.04338758371926616}, "j_per_gene_support": {"IGHJ4*02": 0.999911496238816, "IGHJ5*02": 8.850376117703826e-05}, "v_3p_del": 0, "d_5p_del": 8, "d_3p_del": 3, "j_5p_del": 7, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "GCGTT", "dj_insertion": "GGGACATGAGCGGGC", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [true], "paired-uids": [["51c4c0cd70-igk"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 333}}, {"has_shm_indels": [false, false], "qr_gap_seqs": ["", ""], "gl_gap_seqs": ["", ""], "indel_reversed_seqs": ["", ""], "unique_ids": ["a4b090d0be-igh", "e6fa048856-igh"], "invalid": false, "v_gene": "IGHV2-70*01", "d_gene": "IGHD3-10*03", "j_gene": "IGHJ4*02", "cdr3_length": 39, "mut_freqs": [0.06983240223463687, 0.05307262569832402], "n_mutations": [25, 19], "input_seqs": ["CCGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCTCTCAGCACTAGTGGCATGTGTGTGAGCTGGATCCGTCAGCCCGCAGGGCAGGCCCAGGAGGGGCTTGGACTCATTGATTGGGATGATCATAAATACTACAGCACATCTCTGAAGAACAGACTTACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGATACAGTAACGTATTACTGTGGACGGATACCCTCAATCGTGTACTTGGATTTCTGGGCCCAGGGAACCCTGGTAACCGTCTCCTCAG", "CAGGTCATCTCGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGAACTGCACCTTCTCTGGGTTCTCACTCAGCACGAGTGGAATGTGTGTGAGCTTGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTTCACTCATAGATTGGGATGATCATAAATACTACAGCAAATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACGCCCAAAAACCAGGTGGTCCTTACAATGACCAACATGTACCCTGTGGACAAAGCCACGTCTTACTGTGCACGGATACCTACTATGGTGGAATTTGAACACTGGGGCCAGGGAACCCTGGTCAGCGTCTCCTCAG"], "naive_seq": "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACCTACTATGGTGTACTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[], []], "leader_seqs": ["", ""], "c_gene_seqs": ["", ""], "v_per_gene_support": {"IGHV2-70*01": 1.0}, "d_per_gene_support": {"IGHD3-10*03": 0.9974885981957974, "IGHD6-6*01": 0.0021294073856666707, "IGHD3-16*03": 0.00038199441852192006}, "j_per_gene_support": {"IGHJ4*02": 0.9999974267235101, "IGHJ5*02": 2.5732764872673896e-06}, "v_3p_del": 0, "d_5p_del": 4, "d_3p_del": 18, "j_5p_del": 2, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "C", "dj_insertion": "G", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false, false], "in_frames": [true, true], "stops": [false, false], "paired-uids": [["a4b090d0be-igk"], ["e6fa048856-igk"]], "loci": ["igh", "igh"], "codon_positions": {"v": 288, "j": 324}}, {"has_shm_indels": [false], "qr_gap_seqs": [""], "gl_gap_seqs": [""], "indel_reversed_seqs": [""], "unique_ids": ["bb82ebe094-igh"], "invalid": false, "v_gene": "IGHV2-70*01", "d_gene": "IGHD3-3*01", "j_gene": "IGHJ4*02", "cdr3_length": 39, "mut_freqs": [0.08659217877094973], "n_mutations": [31], "input_seqs": ["CAGGTCACCTTGAGGGAGTTTGGTCCTGCGCTGGTGAAATCCAGACAGATCCTCACCGTGACCTGGACCTTCTCTGGGTTCTCACTCGGCACTAATGGAATGTGTGTGAGCTGGAACCGTCAGCCCCCAGGAAAGGCCATGGAGTGGCTTGGACGCATTGATTGGGATGAGCATAAATACTACAGCACATCGCTGAAAAGCAGGCTCACCATCTCCAAGGACACCTCCAAACACCGGGTGGTCCTTACAATGACCAACATGAACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACTATTGATTTTAGAACTTGATTACTGGGGCTAGGGAACCCTGTTCACCGTCTCCTCAG"], "naive_seq": "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACTGTGGTTATTATACCTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV2-70*01": 1.0}, "d_per_gene_support": {"IGHD3-3*01": 0.9878150009065207, "IGHD3-10*03": 0.00875125776113546, "IGHD3-16*03": 0.0034337413323392097}, "j_per_gene_support": {"IGHJ4*02": 0.9998774786832371, "IGHJ5*02": 0.00012252131675115103}, "v_3p_del": 0, "d_5p_del": 17, "d_3p_del": 0, "j_5p_del": 6, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "T", "dj_insertion": "", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [true], "paired-uids": [["bb82ebe094-igk"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 324}}, {"has_shm_indels": [false], "qr_gap_seqs": [""], "gl_gap_seqs": [""], "indel_reversed_seqs": [""], "unique_ids": ["be186138e0-igh"], "invalid": false, "v_gene": "IGHV1-69*04", "d_gene": "IGHD1-26*01", "j_gene": "IGHJ4*02", "cdr3_length": 48, "mut_freqs": [0.0], "n_mutations": [0], "input_seqs": ["NNNCAGGTCCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGTCCTCGGTGAAGGTCTCCTGCAAGGCTTCTGGAGGCACCTTCAGCAGCTATGCTATCAGCTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGAAGGATCATCCCTATCCTTGGTATAGCAAACTACGCACAGAAGTTCCAGGGCAGAGTCACGATTACCGCGGACAAATCCACGAGCACAGCCTACATGGAGCTGAGCAGCCTGAGATCTGAGGACACGGCCGTGTATTACTGTGCGAGGCGTATAGTGGGAGCTACTACTTACTACTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG"], "naive_seq": "NNNCAGGTCCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGTCCTCGGTGAAGGTCTCCTGCAAGGCTTCTGGAGGCACCTTCAGCAGCTATGCTATCAGCTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGAAGGATCATCCCTATCCTTGGTATAGCAAACTACGCACAGAAGTTCCAGGGCAGAGTCACGATTACCGCGGACAAATCCACGAGCACAGCCTACATGGAGCTGAGCAGCCTGAGATCTGAGGACACGGCCGTGTATTACTGTGCGAGGCGTATAGTGGGAGCTACTACTTACTACTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV1-69*04": 1.0}, "d_per_gene_support": {"IGHD1-26*01": 1.0}, "j_per_gene_support": {"IGHJ4*02": 0.9999999997386197, "IGHJ5*02": 2.6137917103419394e-10}, "v_3p_del": 3, "d_5p_del": 1, "d_3p_del": 0, "j_5p_del": 0, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "GC", "dj_insertion": "TT", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [false], "paired-uids": [["be186138e0-igk"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 333}}, {"has_shm_indels": [true, false], "qr_gap_seqs": ["NNNCAGGTCCAGCTGCTGCAGCCTGGGGCTGAGCTGAAGAAGC............TGCAGGTCTCCTGCAAGGCTTCTGGAGGCACGTTCAGCAGCTTTGCTATCAACTGGGTGAGACAGGCCCCTGGACAAGGGCTTAGGGAGGTCAGGTAGGAGTGGATGGGAAGGATCATCCCTATCCGTGGTATAGCAAACTTCGCACAGAAGTTTCAGGGTGGAGTCACGATTCCCGCGGAAAAATCCACGATGCCAGCCTACATGGAGGTAAGCAGCCTTAGATCCGAGGACACGCTCGTGTATTACTGTGAGAGCCACCACGAGTTATGTCATAAAAATTACTTTGACTATTGGGGCCAGGGAACCCTGGTCACCGTTTGCTCAG", ""], "gl_gap_seqs": ["NNNCAGGTCCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGTCCTCGGTGAAGGTCTCCTGCAAGGCTTCTGGAGGCACCTTCAGCAGCTATGCTATCAGCTGGGTGCGACAGGCCCCTGGACAAGGGCTT...............GAGTGGATGGGAAGGATCATCCCTATCCTTGGTATAGCAAACTACGCACAGAAGTTCCAGGGCAGAGTCACGATTACCGCGGACAAATCCACGAGCACAGCCTACATGGAGCTGAGCAGCCTGAGATCTGAGGACACGGCCGTGTATTACTGTGCGAGCCGCCACGCGTTATACCATAAAACTTACTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", ""], "indel_reversed_seqs": ["NNNCAGGTCCAGCTGCTGCAGCCTGGGGCTGAGCTGAAGAAGCCTGGGTCCTCGGTGCAGGTCTCCTGCAAGGCTTCTGGAGGCACGTTCAGCAGCTTTGCTATCAACTGGGTGAGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGAAGGATCATCCCTATCCGTGGTATAGCAAACTTCGCACAGAAGTTTCAGGGTGGAGTCACGATTCCCGCGGAAAAATCCACGATGCCAGCCTACATGGAGGTAAGCAGCCTTAGATCCGAGGACACGCTCGTGTATTACTGTGAGAGCCACCACGAGTTATGTCATAAAAATTACTTTGACTATTGGGGCCAGGGAACCCTGGTCACCGTTTGCTCAG", ""], "unique_ids": ["09f5010bd3-igh", "eee6809ad6-igh"], "invalid": false, "v_gene": "IGHV1-69*04", "d_gene": "IGHD3-16*03", "j_gene": "IGHJ4*02", "cdr3_length": 48, "mut_freqs": [0.09065934065934066, 0.09065934065934066], "n_mutations": [33, 33], "input_seqs": ["NNNCAGGTCCAGCTGCTGCAGCCTGGGGCTGAGCTGAAGAAGCTGCAGGTCTCCTGCAAGGCTTCTGGAGGCACGTTCAGCAGCTTTGCTATCAACTGGGTGAGACAGGCCCCTGGACAAGGGCTTAGGGAGGTCAGGTAGGAGTGGATGGGAAGGATCATCCCTATCCGTGGTATAGCAAACTTCGCACAGAAGTTTCAGGGTGGAGTCACGATTCCCGCGGAAAAATCCACGATGCCAGCCTACATGGAGGTAAGCAGCCTTAGATCCGAGGACACGCTCGTGTATTACTGTGAGAGCCACCACGAGTTATGTCATAAAAATTACTTTGACTATTGGGGCCAGGGAACCCTGGTCACCGTTTGCTCAG", "NNNCAGGTCGAGCTGCTGCAGCCTGGGGCTGAGCTGAAGAAGCCTGGGGCCTCGCTGCAGGTCTCCTGCAAGGCTTCTGGAGGCACGTTCAGCAGCTTTGCTATCAACTGGGTGAGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGAAGGATCATCCCTATCTGTGGTATAGCAAACTTCGCACAGAAGTTTCAGGGTTGAGTCACGATTCCCGCGGAAAAATCCACGATGCCAGCCTACATGGAGCTAAGCAGCCTGAGATCCGAGGACACGGTCGTGTATAACTGTGAGAGCCGCAACACGTTATATCATAAAACTAACTTTGACTATTGGGGCCAGGGAACCCTGGTCACCGTTTCCTCAG"], "naive_seq": "NNNCAGGTCCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGTCCTCGGTGAAGGTCTCCTGCAAGGCTTCTGGAGGCACCTTCAGCAGCTATGCTATCAGCTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGAAGGATCATCCCTATCCTTGGTATAGCAAACTACGCACAGAAGTTCCAGGGCAGAGTCACGATTACCGCGGACAAATCCACGAGCACAGCCTACATGGAGCTGAGCAGCCTGAGATCTGAGGACACGGCCGTGTATTACTGTGCGAGCCGCCACGCGTTATACCATAAAACTTACTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[], []], "leader_seqs": ["", ""], "c_gene_seqs": ["", ""], "v_per_gene_support": {"IGHV1-69*04": 1.0}, "d_per_gene_support": {"IGHD3-16*03": 0.9336685372120426, "IGHD3-3*01": 0.06559880570253065, "IGHD3-9*01": 0.0007326570854398782}, "j_per_gene_support": {"IGHJ4*02": 0.9999999999985789, "IGHJ5*02": 1.4021616982191138e-12}, "v_3p_del": 3, "d_5p_del": 28, "d_3p_del": 0, "j_5p_del": 3, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "CCGCCACG", "dj_insertion": "ATAAAACTT", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false, false], "in_frames": [true, true], "stops": [true, true], "paired-uids": [["cfe3b29587-igk"], ["bc11af4843-igk"]], "loci": ["igh", "igh"], "codon_positions": {"v": 288, "j": 333}}, {"has_shm_indels": [false, false], "qr_gap_seqs": ["", ""], "gl_gap_seqs": ["", ""], "indel_reversed_seqs": ["", ""], "unique_ids": ["e11acbe3ab-igh", "eee2c7797d-igh"], "invalid": false, "v_gene": "IGHV3-7*01", "d_gene": "IGHD2-15*01", "j_gene": "IGHJ4*02", "cdr3_length": 48, "mut_freqs": [0.03296703296703297, 0.04395604395604396], "n_mutations": [12, 16], "input_seqs": ["NNNTAGGTGCAGCCGGTGGAGTCTGGGGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGACTCTCCTGTGCAGCCTCTGGATTCACCTTTACTAGCTATTGGATGAGCTGGGTCCGCCAGGCTCCAGGGAAGTGGCTGGAGTGTGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGGACTCTGTGAAGGGCCGATTCACCAGCTCCAGAGACAACACCAAGAACTCACTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACCCGGCTGTGTATTACTGTGCGAGAGACCAATCTGCTAGTGGTCTTGGGCGGGGTGACTACTGGGGCCAGGGAAGCCTGGTCACCGTCTCCTCAG", "NNNTAGGTGCAGCGGGTGGAGTATGGGGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGACTCTCCTGAGCAGCCTCTGGATTCACCTTTACTAGCTATTGGATGAGCTGGGTCGGCCAGGCTCCAGGGAAGGGGCTGGAGTGTGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGCACTCTGTGAAGGGCCGACTCACCAGCTCCAGAGACAACGCCAAGAACTCACTGTATCTGCAATTGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGAGCAACCGGCTAGTGGTGTTTGGCGGGCTGAATACTGGGGCCAGGGAAGCCTGGTCACCGTCTCCTCAG"], "naive_seq": "NNNGAGGTGCAGCTGGTGGAGTCTGGGGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGACTCTCCTGTGCAGCCTCTGGATTCACCTTTAGTAGCTATTGGATGAGCTGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAGTGGGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGGACTCTGTGAAGGGCCGATTCACCATCTCCAGAGACAACGCCAAGAACTCACTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGACCAACCGGCTAGTGGTGTTGGGCGGGGTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[], []], "leader_seqs": ["", ""], "c_gene_seqs": ["", ""], "v_per_gene_support": {"IGHV3-7*01": 1.0}, "d_per_gene_support": {"IGHD2-15*01": 0.8865071394001133, "IGHD2-8*02": 0.06261714854126509, "IGHD3-3*01": 0.04667483614876748, "IGHD2-8*01": 0.003361237396511689, "IGHD1-26*01": 0.0008396385133238052}, "j_per_gene_support": {"IGHJ4*02": 0.9999999822484825, "IGHJ5*02": 1.7751514197686412e-08}, "v_3p_del": 0, "d_5p_del": 9, "d_3p_del": 14, "j_5p_del": 7, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "CCAACCGGC", "dj_insertion": "TTGGGCGGGG", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false, false], "in_frames": [true, true], "stops": [true, true], "paired-uids": [["db63559ea9-igk"], ["52387a89c7-igk"]], "loci": ["igh", "igh"], "codon_positions": {"v": 288, "j": 333}}, {"has_shm_indels": [false], "qr_gap_seqs": [""], "gl_gap_seqs": [""], "indel_reversed_seqs": [""], "unique_ids": ["276733008f-igh"], "invalid": false, "v_gene": "IGHV2-70*01", "d_gene": "IGHD2-8*01", "j_gene": "IGHJ4*02", "cdr3_length": 39, "mut_freqs": [0.05865921787709497], "n_mutations": [21], "input_seqs": ["CAGGTCACCTTGAGGGCGTCTGGTCCTGCGCTGCTGAAACCCACAAAGACCCTCACACTTACCTGCACCTTCTCTGGGTTCCCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGCGATGATCATAAATATTATACCACATCTCTTAAGACCCGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCCTACATTGACCAACATGGACCCTGTGAACACAGCCACGTATTACTGTGCACGGATACTCTCTACTATTGGTTTTGTTTACTGGGGCCAGGGTACCCTGGTCACCCTCTCCTCAG"], "naive_seq": "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACTCTGTACTAATGGTTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV2-70*01": 1.0}, "d_per_gene_support": {"IGHD2-8*01": 0.9667034825003873, "IGHD1-26*01": 0.033296517499616006}, "j_per_gene_support": {"IGHJ4*02": 1.0}, "v_3p_del": 0, "d_5p_del": 7, "d_3p_del": 12, "j_5p_del": 5, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "TC", "dj_insertion": "", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [false], "paired-uids": [["276733008f-igk"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 324}}, {"has_shm_indels": [false], "qr_gap_seqs": [""], "gl_gap_seqs": [""], "indel_reversed_seqs": [""], "unique_ids": ["28ce45b82a-igh"], "invalid": false, "v_gene": "IGHV1-69*04", "d_gene": "IGHD1-26*01", "j_gene": "IGHJ4*02", "cdr3_length": 48, "mut_freqs": [0.0], "n_mutations": [0], "input_seqs": ["NNNCAGGTCCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGTCCTCGGTGAAGGTCTCCTGCAAGGCTTCTGGAGGCACCTTCAGCAGCTATGCTATCAGCTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGAAGGATCATCCCTATCCTTGGTATAGCAAACTACGCACAGAAGTTCCAGGGCAGAGTCACGATTACCGCGGACAAATCCACGAGCACAGCCTACATGGAGCTGAGCAGCCTGAGATCTGAGGACACGGCCGTGTATTACTGTGCGAGGCGTATAGTGGGAGCTACTACTTACTACTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG"], "naive_seq": "NNNCAGGTCCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGTCCTCGGTGAAGGTCTCCTGCAAGGCTTCTGGAGGCACCTTCAGCAGCTATGCTATCAGCTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGAAGGATCATCCCTATCCTTGGTATAGCAAACTACGCACAGAAGTTCCAGGGCAGAGTCACGATTACCGCGGACAAATCCACGAGCACAGCCTACATGGAGCTGAGCAGCCTGAGATCTGAGGACACGGCCGTGTATTACTGTGCGAGGCGTATAGTGGGAGCTACTACTTACTACTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV1-69*04": 1.0}, "d_per_gene_support": {"IGHD1-26*01": 0.9999999957069079, "IGHD2-15*01": 4.293090340313514e-09}, "j_per_gene_support": {"IGHJ4*02": 0.999999999857998, "IGHJ5*02": 1.4200256428546358e-10}, "v_3p_del": 3, "d_5p_del": 1, "d_3p_del": 0, "j_5p_del": 0, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "GC", "dj_insertion": "TT", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [false], "paired-uids": [["28ce45b82a-igk"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 333}}, {"has_shm_indels": [false], "qr_gap_seqs": [""], "gl_gap_seqs": [""], "indel_reversed_seqs": [""], "unique_ids": ["3542bd38d8-igh"], "invalid": false, "v_gene": "IGHV2-70*01", "d_gene": "IGHD3-3*01", "j_gene": "IGHJ4*02", "cdr3_length": 39, "mut_freqs": [0.0782122905027933], "n_mutations": [28], "input_seqs": ["CCGGTCACCTTGAGGGAGTCTGGTCCCGCGCTGGTTAAACCCACACAGACCCTCACACTGACCTGCAACTTCTCTGGGCTCTCACTCAGCACTAGTGTAATGCGTGTGAGCTGGATCCGTCAGCCCCCAAGGAAGGCCCTGGAGTGGGATGCACTCATTGTTTGGGATGATCATATATACTACAGCACATCTCTGAAGACCAGGCTCACTATCTCCAAGGACACCTCCACAAACCCGGTGGTCCTTACAATGACCAACATGGTCCCTGTGGATACAGCCACGTATTACTGTGCACTGATACTCGCGAATTTGGATTTAGATTACTGGGGCCACGGAACTCTGTTCACCGTCTCCTCAA"], "naive_seq": "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACTCGCGATTTTTGACTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV2-70*01": 1.0}, "d_per_gene_support": {"IGHD3-3*01": 0.6787543160763233, "IGHD3-16*03": 0.3080937839866766, "IGHD3-9*01": 0.01315189993699562}, "j_per_gene_support": {"IGHJ4*02": 0.9999702470345994, "IGHJ5*02": 2.9752965406579544e-05}, "v_3p_del": 0, "d_5p_del": 6, "d_3p_del": 16, "j_5p_del": 3, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "TCG", "dj_insertion": "", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [false], "paired-uids": [["3542bd38d8-igk"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 324}}, {"has_shm_indels": [false, false, false], "qr_gap_seqs": ["", "", ""], "gl_gap_seqs": ["", "", ""], "indel_reversed_seqs": ["", "", ""], "unique_ids": ["35fc655801-igh", "7ba384a461-igh", "7d4166ae48-igh"], "invalid": false, "v_gene": "IGHV2-70*01", "d_gene": "IGHD7-27*01", "j_gene": "IGHJ4*02", "cdr3_length": 39, "mut_freqs": [0.0, 0.0, 0.00558659217877095], "n_mutations": [0, 0, 2], "input_seqs": ["CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACGCCGAACTGGGGACGTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACGCCGAACTGGGGACGTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACCCCCAACTGGGGACGTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG"], "naive_seq": "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACGCCGAACTGGGGACGTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[], [], []], "leader_seqs": ["", "", ""], "c_gene_seqs": ["", "", ""], "v_per_gene_support": {"IGHV2-70*01": 1.0}, "d_per_gene_support": {"IGHD7-27*01": 0.9998556794105843, "IGHD1-1*01": 0.00014412056798953168, "IGHD3-9*01": 2.000214290266751e-07}, "j_per_gene_support": {"IGHJ4*02": 0.9999990543118211, "IGHJ5*02": 9.456881762103001e-07}, "v_3p_del": 0, "d_5p_del": 2, "d_3p_del": 0, "j_5p_del": 7, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "GCCG", "dj_insertion": "CGT", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false, false, false], "in_frames": [true, true, true], "stops": [false, false, false], "paired-uids": [["35fc655801-igk"], ["7ba384a461-igk"], []], "loci": ["igh", "igh", "igh"], "codon_positions": {"v": 288, "j": 324}}, {"has_shm_indels": [false], "qr_gap_seqs": [""], "gl_gap_seqs": [""], "indel_reversed_seqs": [""], "unique_ids": ["3c5f4c778a-igh"], "invalid": false, "v_gene": "IGHV2-70*01", "d_gene": "IGHD1-1*01", "j_gene": "IGHJ4*02", "cdr3_length": 39, "mut_freqs": [0.04748603351955307], "n_mutations": [17], "input_seqs": ["CAGGTCACCTTGAGGGCGTCTGGTCCTCCGCTGCTGAAACCCACAAAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCCCACTCAGCACGAGTGGAATGTGTGTGAGCTGGATCCTTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTCATTGGGATGCTCATAAATACTACAGCACATCTCTGAAGACCAAGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACCTGGACCCTGTGAACACAGCCACGTATTACTGTGCACGGATACTCCCAACTGTCGGTTTTGATTACTGGGGCCAGGGCACCCTGGTCACCCTCTCCTCAA"], "naive_seq": "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACTCCCAACTGTCGGTTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV2-70*01": 1.0}, "d_per_gene_support": {"IGHD1-1*01": 0.488415118115327, "IGHD7-27*01": 0.48029125259610855, "IGHD2-8*02": 0.01633765712142096, "IGHD2-2*01": 0.014955972167129735}, "j_per_gene_support": {"IGHJ4*02": 1.0}, "v_3p_del": 0, "d_5p_del": 4, "d_3p_del": 7, "j_5p_del": 5, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "TCC", "dj_insertion": "TCGGT", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [false], "paired-uids": [["3c5f4c778a-igk"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 324}}, {"has_shm_indels": [false, false, false, false], "qr_gap_seqs": ["", "", "", ""], "gl_gap_seqs": ["", "", "", ""], "indel_reversed_seqs": ["", "", "", ""], "unique_ids": ["453132f3ab-igh", "7334912e1e-igh", "f094dfd68a-igh", "b997fa9304-igh"], "invalid": false, "v_gene": "IGHV3-33*01", "d_gene": "IGHD1-14*01", "j_gene": "IGHJ6*02", "cdr3_length": 54, "mut_freqs": [0.03513513513513514, 0.03783783783783784, 0.032432432432432434, 0.024324324324324326], "n_mutations": [13, 14, 12, 9], "input_seqs": ["NNNCAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACCCTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGCTATGTCATGGACTGGGTCCGCCAGGCACCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGAACAGGCAGCGGAACCAGAACTTTCCTACGGTATAGACGTCTGGGGCCAAGGGACCACGGTCACCGTCTCCTCAG", "NNNCAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTAGGAGGTCCCTGAGACTCTCCTTTTCAGCGTCTGGATTCACCTTCAGTAGGTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCATACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGTTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGTCCCGGCTGTGTATTACTGTGCGAGAGAGCCGGAACTGGTAGCACTAGTTCCCTACGGTATGGACGTCTGGGGCCAAGGGACCACGGTCACCGTCTCCTCAG", "NNNCAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGGTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGGAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGTCACGGCTGTGGATTACTGTGCGAGAGGGCCGGCACCGGAACCGCTACTTACCTACGGTATGGACGTCTGGGGCCAAGGGACCACGGGCACCGTCTCCTCAG", "NNNCTGGTTCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCTGAATTCACCTTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATCTGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGGGGACACGGCTGTGTATTACTGTGCGAGAGAGCCGACACAGGAACCACGAGTTCGCTACGGTATGGACGTCTGGGGCCAAGGGACCACGGTCACCGTCTCCTCAG"], "naive_seq": "NNNCAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGAGCCGGAACCGGAACCACGAGTTTGCTACGGTATGGACGTCTGGGGCCAAGGGACCACGGTCACCGTCTCCTCAG", "duplicates": [[], [], [], []], "leader_seqs": ["", "", "", ""], "c_gene_seqs": ["", "", "", ""], "v_per_gene_support": {"IGHV3-33*01": 1.0}, "d_per_gene_support": {"IGHD1-14*01": 0.9999976766879956, "IGHD1-1*01": 1.6037445435736297e-06, "IGHD6-19*01": 3.624470931209077e-07, "IGHD2-15*01": 3.433366709190294e-07, "IGHD1-26*01": 1.3783696953904691e-08}, "j_per_gene_support": {"IGHJ6*02": 1.0}, "v_3p_del": 0, "d_5p_del": 5, "d_3p_del": 0, "j_5p_del": 13, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "GCCGG", "dj_insertion": "GAGTTTG", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false, false, false, false], "in_frames": [true, true, true, true], "stops": [false, false, false, false], "paired-uids": [["453132f3ab-igk"], ["7334912e1e-igk"], ["f094dfd68a-igk"], []], "loci": ["igh", "igh", "igh", "igh"], "codon_positions": {"v": 288, "j": 339}}, {"has_shm_indels": [false, false], "qr_gap_seqs": ["", ""], "gl_gap_seqs": ["", ""], "indel_reversed_seqs": ["", ""], "unique_ids": ["665985d2d1-igh", "d1ee7f9ce6-igh"], "invalid": false, "v_gene": "IGHV3-33*01", "d_gene": "IGHD6-19*01", "j_gene": "IGHJ5*02", "cdr3_length": 66, "mut_freqs": [0.015706806282722512, 0.01832460732984293], "n_mutations": [6, 7], "input_seqs": ["NNNCAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCACCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCATCTGGATTCACCGTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGAATTACTGTGCGAGAGAGGCTGGGTTAGATTTTGGGTTTGGTTAGTGTGCGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "NNNCAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCACCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCATCTGGATTCACCGTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGAATTACTGTGCGAGAGAGGCTGGGTGAGATTTTGGGTTTGCTTACTATGGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG"], "naive_seq": "NNNCAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGAGGCTGGGTGAGATTTTGGGTTTGGTTAGTGTGGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[], []], "leader_seqs": ["", ""], "c_gene_seqs": ["", ""], "v_per_gene_support": {"IGHV3-33*01": 1.0}, "d_per_gene_support": {"IGHD6-19*01": 0.5498427718139053, "IGHD3-3*01": 0.4188548198724743, "IGHD3-16*03": 0.028855233142586194, "IGHD3-9*01": 0.002447175171016475}, "j_per_gene_support": {"IGHJ5*02": 1.0}, "v_3p_del": 0, "d_5p_del": 12, "d_3p_del": 3, "j_5p_del": 0, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "", "dj_insertion": "GTGAGATTTTGGGTTTGGTTAGTGTGGGA", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false, false], "in_frames": [true, true], "stops": [true, true], "paired-uids": [["665985d2d1-igk"], ["d1ee7f9ce6-igk"]], "loci": ["igh", "igh"], "codon_positions": {"v": 288, "j": 351}}, {"has_shm_indels": [false], "qr_gap_seqs": [""], "gl_gap_seqs": [""], "indel_reversed_seqs": [""], "unique_ids": ["789d880ef2-igh"], "invalid": false, "v_gene": "IGHV2-70*01", "d_gene": "IGHD3-9*01", "j_gene": "IGHJ4*02", "cdr3_length": 39, "mut_freqs": [0.061452513966480445], "n_mutations": [22], "input_seqs": ["CAGGTCACCTTGAGGGAGTTTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCTCACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCTCTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGGACTCATTTATTGGTATGATCATAAATAATACGGCACATCGCTGAAGAGGAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGATCCTTACAATTACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTTCACGGATACACTAAAGTGTGACTGTTGATTCCTGGGGCCAGGGAACCCTGGTCACCGTATCCTCAG"], "naive_seq": "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACACGATATTTTGACTGTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV2-70*01": 1.0}, "d_per_gene_support": {"IGHD3-9*01": 0.9520465873464513, "IGHD1-26*01": 0.047953412653544795}, "j_per_gene_support": {"IGHJ4*02": 0.9986875587196622, "IGHJ5*02": 0.0013124412803428623}, "v_3p_del": 0, "d_5p_del": 5, "d_3p_del": 11, "j_5p_del": 6, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "", "dj_insertion": "", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [true], "paired-uids": [["789d880ef2-igk"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 324}}, {"has_shm_indels": [false], "qr_gap_seqs": [""], "gl_gap_seqs": [""], "indel_reversed_seqs": [""], "unique_ids": ["b9148494e2-igh"], "invalid": false, "v_gene": "IGHV1-2*02", "d_gene": "IGHD6-6*01", "j_gene": "IGHJ3*02", "cdr3_length": 63, "mut_freqs": [0.0], "n_mutations": [0], "input_seqs": ["NNNCAGGTGCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGGCCTCAGTGAAGGTCTCCTGCAAGGCTTCTGGATACACCTTCACCGGCTACTATATGCACTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGATGGATCAACCCTAACAGTGGTGGCACAAACTATGCACAGAAGTTTCAGGGCAGGGTCACCATGACCAGGGACACGTCCATCAGCACAGCCTACATGGAGCTGAGCAGGCTGAGATCTGACGACACGGCCGTGTATTACTGTGCGAGAACCGGACTGCTCTGTATAGCAGCTCGTCCCGATGGTGATGCTTTTGATATCTGGGGCCAAGGGACAATGGTCACCGTCTCTTCAG"], "naive_seq": "NNNCAGGTGCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGGCCTCAGTGAAGGTCTCCTGCAAGGCTTCTGGATACACCTTCACCGGCTACTATATGCACTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGATGGATCAACCCTAACAGTGGTGGCACAAACTATGCACAGAAGTTTCAGGGCAGGGTCACCATGACCAGGGACACGTCCATCAGCACAGCCTACATGGAGCTGAGCAGGCTGAGATCTGACGACACGGCCGTGTATTACTGTGCGAGAACCGGACTGCTCTGTATAGCAGCTCGTCCCGATGGTGATGCTTTTGATATCTGGGGCCAAGGGACAATGGTCACCGTCTCTTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV1-2*02": 1.0}, "d_per_gene_support": {"IGHD6-6*01": 0.9999992854308881, "IGHD6-19*01": 6.887629223866832e-07, "IGHD2-15*01": 2.5806183206409083e-08}, "j_per_gene_support": {"IGHJ3*02": 1.0}, "v_3p_del": 2, "d_5p_del": 2, "d_3p_del": 0, "j_5p_del": 0, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "ACCGGACTGCTCT", "dj_insertion": "CGATGG", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [false], "paired-uids": [["b9148494e2-igk"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 348}}, {"has_shm_indels": [false, false, true, false], "qr_gap_seqs": ["", "", "CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTGTTCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACAGGGGCTCGATCCGCCAGCCCCCAAGTAAGGGGCTGGAGTGGATTGGGAGTATCTATTATAGTGTGAGCACC.ACTACAACCAGTCTCTCAAGAGTCGAGTCTCCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAACTGAGCTCTGTGACTCCCGCAGAAACGGCGGCGTATTACTGTGCGAGAAAGCAAAGCGACACAGTACCCCCCACTGTCCTCGAACGGGACTACTGGGGCCAGGGAACCCTGGTTACCGTCTCCTCAG", ""], "gl_gap_seqs": ["", "", "CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGAAGCCTTCGGAGACCCTGTCCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACTGGGGCTGGATCCGCCAGCCCCCAGGGAAGGGGCTGGAGTGGATTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCCGTCCCTCAAGAGTCGAGTCACCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGCTCTGTGACCGCCGCAGACACGGCTGTGTATTACTGTGCGAGCGAGCCAAGTATAGCAGTACCCCCCACGACCCTCGGGCGGGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", ""], "indel_reversed_seqs": ["", "", "CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTGTTCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACAGGGGCTCGATCCGCCAGCCCCCAAGTAAGGGGCTGGAGTGGATTGGGAGTATCTATTATAGTGTGAGCACCTACTACAACCAGTCTCTCAAGAGTCGAGTCTCCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAACTGAGCTCTGTGACTCCCGCAGAAACGGCGGCGTATTACTGTGCGAGAAAGCAAAGCGACACAGTACCCCCCACTGTCCTCGAACGGGACTACTGGGGCCAGGGAACCCTGGTTACCGTCTCCTCAG", ""], "unique_ids": ["253ca59333-igh", "8d79fca804-igh", "a2238f4e9a-igh", "a3baa83300-igh"], "invalid": false, "v_gene": "IGHV4-39*01", "d_gene": "IGHD6-19*01", "j_gene": "IGHJ4*02", "cdr3_length": 57, "mut_freqs": [0.06914893617021277, 0.06914893617021277, 0.08244680851063829, 0.07180851063829788], "n_mutations": [26, 26, 31, 27], "input_seqs": ["CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTGTCCCTCACCTGCACTGTCTCTGTTGGCTCCATCAGCAGAAGTAGTTACTACTGCGGCCCGATCCGCCAGCCCCCAGGTAAGGGGCTGGAGTGGATTCGGAGTATCTATTATAGTGGGAGCACCTACTACATCCAGTCCCTCAAGAGTCGAGTCACCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGCTCTGTGACCGCCGCAGACACGGCTGCGTATTACTGTGCGAGCCAACCATGCATATCAGTACCTCCTACTAAACTCTCGCAAGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "CAGCTGCAGCAGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTATCCCTCACCTGCACTGGCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACAGGGGCTCGATCCGCCAGCCCCCAGGTAAGGGGCTGGAGTGGATTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCAGTCCCTCAAGAGTCGAGTCTCCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGGTCTGTGACCGCGGCAGACACGGCTGCGTATTACTGTGCGAGCGAGCAATGTAAAACAGTACCTCCTACTTCCATCGGTCGAGACTACTGGGGCCAGGGAACCCTGGTTCCCGTCTCCTCAG", "CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTGTTCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACAGGGGCTCGATCCGCCAGCCCCCAAGTAAGGGGCTGGAGTGGATTGGGAGTATCTATTATAGTGTGAGCACCACTACAACCAGTCTCTCAAGAGTCGAGTCTCCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAACTGAGCTCTGTGACTCCCGCAGAAACGGCGGCGTATTACTGTGCGAGAAAGCAAAGCGACACAGTACCCCCCACTGTCCTCGAACGGGACTACTGGGGCCAGGGAACCCTGGTTACCGTCTCCTCAG", "CAGCTGCAGCAGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTATCCCTCACCTGCACTGGCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACAGGGGCTCGATCCGCCAGCCCCCAGGTAAGGGGCTGGAGTGGATTGGGAGTATCTATTAAAGTGGGAGCACCTACTACAACCAGTCCCTCAAGAGTCGAGTCTCCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGGTCTGTGACCGCGGCAGACACGGCTGCGTATTACTGTGCGAGCTAGCAATGTAAAACAGTACCTCCTACGTCCATCGGTCGAGACTACTGGGGCCAGGGAACCCTGGTTCCCGTCTCCTCAG"], "naive_seq": "CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGAAGCCTTCGGAGACCCTGTCCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACTGGGGCTGGATCCGCCAGCCCCCAGGGAAGGGGCTGGAGTGGATTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCCGTCCCTCAAGAGTCGAGTCACCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGCTCTGTGACCGCCGCAGACACGGCTGTGTATTACTGTGCGAGCGAGCCAAGTATAGCAGTACCCCCCACGACCCTCGGGCGGGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[], [], [], []], "leader_seqs": ["", "", "", ""], "c_gene_seqs": ["", "", "", ""], "v_per_gene_support": {"IGHV4-39*01": 1.0}, "d_per_gene_support": {"IGHD6-19*01": 0.9833480536021382, "IGHD6-6*01": 0.015956577558223453, "IGHD1-1*01": 0.0006953688396342909}, "j_per_gene_support": {"IGHJ4*02": 0.999982268710881, "IGHJ5*02": 1.7731289131899734e-05}, "v_3p_del": 3, "d_5p_del": 2, "d_3p_del": 9, "j_5p_del": 8, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "CGAGCCAA", "dj_insertion": "ACCCCCCACGACCCTCGGGCGG", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false, false, false, false], "in_frames": [true, true, false, true], "stops": [false, false, true, true], "paired-uids": [["253ca59333-igl"], ["8d79fca804-igl"], ["a2238f4e9a-igl"], ["a3baa83300-igl"]], "loci": ["igh", "igh", "igh", "igh"], "codon_positions": {"v": 288, "j": 342}}, {"has_shm_indels": [false, false], "qr_gap_seqs": ["", ""], "gl_gap_seqs": ["", ""], "indel_reversed_seqs": ["", ""], "unique_ids": ["7588f09c07-igh", "aa25e6c0ce-igh"], "invalid": false, "v_gene": "IGHV4-39*01", "d_gene": "IGHD6-19*01", "j_gene": "IGHJ4*02", "cdr3_length": 57, "mut_freqs": [0.05319148936170213, 0.061170212765957445], "n_mutations": [20, 23], "input_seqs": ["CAGCTGCAGCTGCAGGAGTCGAGCCCAGGACTGGTGATGCCTTCGGAGACCTTGTCCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACTGGGGCTGGATCCGCCAGCCCCCAGGTAAGGGGCTGGAGTGGCTTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCAGTCAGTCAAGAGTCGAGTCACCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGATGAGCTCTGTGACCGCCGCAGACACGGCTGCGTATTACTGTGCGAGCCCTCCTTGGATAGCAGGGCTTCGTTCAAAGATAGCACTAGACTACTGGGACCAGGGAACCCTGGTCACCGTCTCCTCAG", "CAGCTGCAGCTGCAGGAGTCGAGCCCAGGACTGGTGATGCCTTCGGAGACCTTGTCCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACGACTGGGGCTTGATCCGCCAGCCCCCAGGTAAGGGGCTGGAGTGGCTTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCAGTCCCTCAAGAGTCGATTCACCATATCCGTAGACCCGTCCAAGAACCAGTTCTCCCTGAAGCTGCGCTCTGTGACCGCCGCAGACACGGCTGCGTATTACTGTGCGAGCAAACATTGAATAGCAGTATCTAGTACTTCGATAGCACCGGACTACTGGGACAAGGGAACCCTGGTCACCGTCTCCTCAG"], "naive_seq": "CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGAAGCCTTCGGAGACCCTGTCCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACTGGGGCTGGATCCGCCAGCCCCCAGGGAAGGGGCTGGAGTGGATTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCCGTCCCTCAAGAGTCGAGTCACCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGCTCTGTGACCGCCGCAGACACGGCTGTGTATTACTGTGCGAGCCCACCTTGGATAGCAGTGGCTGGTACAACGATAGCACCGGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[], []], "leader_seqs": ["", ""], "c_gene_seqs": ["", ""], "v_per_gene_support": {"IGHV4-39*01": 1.0}, "d_per_gene_support": {"IGHD6-19*01": 0.9999979095272203, "IGHD6-6*01": 2.090456509010692e-06, "IGHD1-26*01": 1.6260047500959325e-11}, "j_per_gene_support": {"IGHJ4*02": 0.9999982940214863, "IGHJ5*02": 1.705978509508022e-06}, "v_3p_del": 3, "d_5p_del": 4, "d_3p_del": 0, "j_5p_del": 8, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "CCCACCTTGG", "dj_insertion": "AACGATAGCACCG", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false, false], "in_frames": [true, true], "stops": [false, true], "paired-uids": [["7588f09c07-igl"], ["aa25e6c0ce-igl"]], "loci": ["igh", "igh"], "codon_positions": {"v": 288, "j": 342}}, {"has_shm_indels": [false], "qr_gap_seqs": [""], "gl_gap_seqs": [""], "indel_reversed_seqs": [""], "unique_ids": ["b739ce37b7-igh"], "invalid": false, "v_gene": "IGHV1-69*04", "d_gene": "IGHD2-21*01", "j_gene": "IGHJ4*02", "cdr3_length": 48, "mut_freqs": [0.07692307692307693], "n_mutations": [28], "input_seqs": ["NNNCAGGTCCAGCTGATGCAGTCTTGGGCTGAGCTGAAGAAGCCTGTGTCCTCGCTGAAGGTCTCCTGCAAGGCTTCTGGAGGCACCTTCAGCAGCTAAGATATCAACTGTGTGCGACAGGCCCCTGGACAGGGGCTTGAGTGGATGGGAAGGATCATCCCTATCCTTGGTATAGCAAACATCGCACAGAAGTTCCACGGCAGAGTCACGATTCCCGTGGAAATATACACGATGACAGCCTACATGGAGCTGAGCAGCATGAGATCCGGGGACACGGCCGTGTATTACTGTGGGAGATGACGGGAGGGAGATGGTGTTGATTACTTTGACTATTGGGGCCAGGGAACCCTGGTCACCGTCTTCTCAC"], "naive_seq": "NNNCAGGTCCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGTCCTCGGTGAAGGTCTCCTGCAAGGCTTCTGGAGGCACCTTCAGCAGCTATGCTATCAGCTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGAAGGATCATCCCTATCCTTGGTATAGCAAACTACGCACAGAAGTTCCAGGGCAGAGTCACGATTACCGCGGACAAATCCACGAGCACAGCCTACATGGAGCTGAGCAGCCTGAGATCTGAGGACACGGCCGTGTATTACTGTGCGAGATGACGGGAGGGAGATGGTGGTGATTACTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV1-69*04": 1.0}, "d_per_gene_support": {"IGHD2-21*01": 1.0}, "j_per_gene_support": {"IGHJ4*02": 1.0}, "v_3p_del": 2, "d_5p_del": 9, "d_3p_del": 9, "j_5p_del": 2, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "TGACGGGAGGGAGA", "dj_insertion": "", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [true], "paired-uids": [["b739ce37b7-igl"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 333}}, {"has_shm_indels": [false, false, true, true, false, false], "qr_gap_seqs": ["", "", "CAGCTGCAGCAGCAGGAGTCGGGCCCAAGGGACTGGTGATGCCTTCGGAGACCTTATCCCTCACCTGCACTGGCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACAGGGGCTCGATCCGCCAGCCCCCAGGTAAGGGGCTGGACTGGATTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCAGTCTCTCAAGAGTCGAGTCTCCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGGTCTGTGACCGCGGCAGACACGGCTGCGTATTACTGTGCGAGCGAGCAATGTAAAACAGTACCTCCTACTTCCATCGCTCGCGACTACTGGGGCCAGGGAACCCTGGTTCCCGTCTCCTCAG", "CAGCTGCAGCAGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTATCCCTCACCTGCACTGGCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACAGGGGCTCGATCCGCCAGACCCCAGGTAAGGGGCTGGAGTGGATTGGGACTATCTATTACATTACTGGGAGCACCTACTACGACCAGTCCCTCAAGAGTCGAGTCTCCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGGTCTGTGACCGCGGCAGACACGGCTGCGTATTACTGTGCGAGCGAGCAATGTAAAACAGTACCACCTACTTCCATCGCTCGAGACTTCTGGGGCCAGGGAACCCTGGTTCCCGTCTCCTCAG", "", ""], "gl_gap_seqs": ["", "", "CAGCTGCAGCTGCAGGAGTCGGGCCCA..GGACTGGTGAAGCCTTCGGAGACCCTGTCCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACTGGGGCTGGATCCGCCAGCCCCCAGGGAAGGGGCTGGAGTGGATTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCCGTCCCTCAAGAGTCGAGTCACCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGCTCTGTGACCGCCGCAGACACGGCTGTGTATTACTGTGCGAGCCAGCCGTGTATAGCAGTACCTCTTGCTTGGATCGCGCGGGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGAAGCCTTCGGAGACCCTGTCCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACTGGGGCTGGATCCGCCAGCCCCCAGGGAAGGGGCTGGAGTGGATTGGGAGTATCTATTA...TAGTGGGAGCACCTACTACAACCCGTCCCTCAAGAGTCGAGTCACCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGCTCTGTGACCGCCGCAGACACGGCTGTGTATTACTGTGCGAGCCAGCCGTGTATAGCAGTACCTCTTGCTTGGATCGCGCGGGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "", ""], "indel_reversed_seqs": ["", "", "CAGCTGCAGCAGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTATCCCTCACCTGCACTGGCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACAGGGGCTCGATCCGCCAGCCCCCAGGTAAGGGGCTGGACTGGATTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCAGTCTCTCAAGAGTCGAGTCTCCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGGTCTGTGACCGCGGCAGACACGGCTGCGTATTACTGTGCGAGCGAGCAATGTAAAACAGTACCTCCTACTTCCATCGCTCGCGACTACTGGGGCCAGGGAACCCTGGTTCCCGTCTCCTCAG", "CAGCTGCAGCAGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTATCCCTCACCTGCACTGGCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACAGGGGCTCGATCCGCCAGACCCCAGGTAAGGGGCTGGAGTGGATTGGGACTATCTATTATACTGGGAGCACCTACTACGACCAGTCCCTCAAGAGTCGAGTCTCCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGGTCTGTGACCGCGGCAGACACGGCTGCGTATTACTGTGCGAGCGAGCAATGTAAAACAGTACCACCTACTTCCATCGCTCGAGACTTCTGGGGCCAGGGAACCCTGGTTCCCGTCTCCTCAG", "", ""], "unique_ids": ["0eb272ee70-igh", "4d37fe487e-igh", "b02ee7754a-igh", "b1e56e40a1-igh", "ddcf0ca433-igh", "9ed10b6475-igh"], "invalid": false, "v_gene": "IGHV4-39*01", "d_gene": "IGHD6-19*01", "j_gene": "IGHJ4*02", "cdr3_length": 57, "mut_freqs": [0.07180851063829788, 0.08244680851063829, 0.07446808510638298, 0.0851063829787234, 0.06648936170212766, 0.0797872340425532], "n_mutations": [27, 31, 28, 32, 25, 30], "input_seqs": ["CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTGTCCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGAAGTAGTAGTTCCTACTGGGGCCGGATCCGCCAGCCCCCAGGTAAGGGGGTGGAGTGGATTGGGAGTATCTATGATAGTGGTAGCACCTACTATAACCAGTCCCTCAAGAGTCGAGTCACCATATCTGTAGACGCGTCCAAGAAGCAGTTCTCCCTGAAGCTGAGCTCTGTGCCCGCCGCAGACACGGCTGCGTATTACTGTGCGAGAGAGTTGTGTATAGCAGTGCTTCTTGCTTGGATAGCCCCGGACTACTGGGGCTAGGGAACCCTGGTCACCGTCTCCTCTG", "CAGCTGCAGCTGCAGGAGTCGAACCCAGGACTGGTGATGCCTTCGGAGACCTTGTCCCTCACCTGCACTGTCTATGGTGGCTCCATCACCAGTAGTAGTTACTACTGGGGCTGGATCCGCCAGCCCCCAGGTAAGGGGCTGGAGTGGCTTGGGAGTATCTCTTATAGTGGGAGCACATACTACAACCAGTCACTCAAGAGTCGAGTCACCATATCCGTAGACACGTCCATGAACCAGTTCTCCCTGAAGCTGAGCTCTGTCACCGCCGCAGACACGGCTGCGTCTTACTGTGCGAGCCTGCCTAGAAGAGAAGTACCTCTTTATAAGATAGCTCAAGACTACTGGGACCAGGGAACCCTGGTCACCGTCTCCTCAG", "CAGCTGCAGCAGCAGGAGTCGGGCCCAAGGGACTGGTGATGCCTTCGGAGACCTTATCCCTCACCTGCACTGGCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACAGGGGCTCGATCCGCCAGCCCCCAGGTAAGGGGCTGGACTGGATTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCAGTCTCTCAAGAGTCGAGTCTCCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGGTCTGTGACCGCGGCAGACACGGCTGCGTATTACTGTGCGAGCGAGCAATGTAAAACAGTACCTCCTACTTCCATCGCTCGCGACTACTGGGGCCAGGGAACCCTGGTTCCCGTCTCCTCAG", "CAGCTGCAGCAGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTATCCCTCACCTGCACTGGCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACAGGGGCTCGATCCGCCAGACCCCAGGTAAGGGGCTGGAGTGGATTGGGACTATCTATTACATTACTGGGAGCACCTACTACGACCAGTCCCTCAAGAGTCGAGTCTCCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGGTCTGTGACCGCGGCAGACACGGCTGCGTATTACTGTGCGAGCGAGCAATGTAAAACAGTACCACCTACTTCCATCGCTCGAGACTTCTGGGGCCAGGGAACCCTGGTTCCCGTCTCCTCAG", "CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTGTCCCTCACCTGCACTGTCTCTGTTGGCTCCATCAGCAGAAGTAGTTACTACTGCGGCCCGATCCGCCAGCCCCCAGGTAAGGGGCTGGAGTGGATTCGGAGTATCTATTATAGTGGGAGCACCTACTACATCCAGTCCCTCAAGAGTCGAGTCACCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGCTCTGTGACCGCCGCAGACACGGCTGCGTATTACTGTGCGAGCCAGCCTTGCATATCAGTACCTCCTACAAAACTCTCGCAAGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "CAGCTGCAGCTGCAGGAGTCGAGCCCAGGACTGGTGATGCCTTCGGAGACCTTGTCCCTCACCTGCACTGTCTGTGGTGGCTCCATCAGCAGTAGTAGTTACGACTGGGGCTTGATCCGCCAGCCCCCAGGTAAGGGGCTGGAGTGGCTTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCAGTCCCTCAAGAGTCGATTCACCATATCCGTAGAGCCGTCCAAGAACCAGTTCTCCCTGAAGCTGAGCTCTGTGACCGCCGCCGACACGGCTGCGTATTACTGTCCGAGTTAGCTTTGAATAGCAGTCCCTCGTACTTCGATATCACCGGACTACTGGGACAAGGGAACCCTGGTCACCGTCTCCTCAG"], "naive_seq": "CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGAAGCCTTCGGAGACCCTGTCCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACTGGGGCTGGATCCGCCAGCCCCCAGGGAAGGGGCTGGAGTGGATTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCCGTCCCTCAAGAGTCGAGTCACCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGCTCTGTGACCGCCGCAGACACGGCTGTGTATTACTGTGCGAGCCAGCCGTGTATAGCAGTACCTCTTGCTTGGATCGCGCGGGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[], [], [], [], [], []], "leader_seqs": ["", "", "", "", "", ""], "c_gene_seqs": ["", "", "", "", "", ""], "v_per_gene_support": {"IGHV4-39*01": 1.0}, "d_per_gene_support": {"IGHD6-19*01": 0.9369032357955595, "IGHD6-6*01": 0.058574356983753295, "IGHD1-14*01": 0.001326241506365111, "IGHD3-16*03": 0.0011458274120855697, "IGHD2-2*01": 0.0010424013132667286, "IGHD2-15*01": 0.0010078627570677952, "IGHD3-9*01": 7.423186939560802e-08}, "j_per_gene_support": {"IGHJ4*02": 0.9999941657499907, "IGHJ5*02": 5.834250005393095e-06}, "v_3p_del": 3, "d_5p_del": 2, "d_3p_del": 9, "j_5p_del": 8, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "CCAGCCGT", "dj_insertion": "ACCTCTTGCTTGGATCGCGCGG", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false, false, false, false, false, false], "in_frames": [true, true, false, true, true, true], "stops": [true, false, true, false, false, true], "paired-uids": [["0eb272ee70-igl"], ["4d37fe487e-igl"], ["b02ee7754a-igl"], ["b1e56e40a1-igl"], ["ddcf0ca433-igl"], []], "loci": ["igh", "igh", "igh", "igh", "igh", "igh"], "codon_positions": {"v": 288, "j": 342}}, {"has_shm_indels": [true], "qr_gap_seqs": ["NNNTTGGTGCAGCTGGTGGAGTCTGGGAGTGTATGGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGGCTCTCATGGGCAGCCTCTGGATTCACCTTTACTAGCTATTTGATGAGCTGGGTTGGCCAGGCTCCAGGGAAGGGGCTGGAGTGCGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGGACTCTGTGAAGGGCCGATTCACTACTCTCCAGAGACAACGCCAAGAACTCACTGTATGTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGGTCCATCCCCTGGTGGTCCTGTGTGGGGTGACTACTGGGGCCAGGGAATCCTGGTCACCGTCTCCTCAG"], "gl_gap_seqs": ["NNNGAGGTGCAGCTGGTGGAGTCTGG........GGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGACTCTCCTGTGCAGCCTCTGGATTCACCTTTAGTAGCTATTGGATGAGCTGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAGTGGGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGGACTCTGTGAAGGGCCGATTCACCA.TCTCCAGAGACAACGCCAAGAACTCACTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGGTCCATCCCCTGGTGGTCCTGTGTGGGGTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG"], "indel_reversed_seqs": ["NNNTTGGTGCAGCTGGTGGAGTCTGGGGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGGCTCTCATGGGCAGCCTCTGGATTCACCTTTACTAGCTATTTGATGAGCTGGGTTGGCCAGGCTCCAGGGAAGGGGCTGGAGTGCGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGGACTCTGTGAAGGGCCGATTCACTATCTCCAGAGACAACGCCAAGAACTCACTGTATGTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGGTCCATCCCCTGGTGGTCCTGTGTGGGGTGACTACTGGGGCCAGGGAATCCTGGTCACCGTCTCCTCAG"], "unique_ids": ["14195e4958-igh"], "invalid": false, "v_gene": "IGHV3-7*01", "d_gene": "IGHD2-8*02", "j_gene": "IGHJ4*02", "cdr3_length": 48, "mut_freqs": [0.03571428571428571], "n_mutations": [13], "input_seqs": ["NNNTTGGTGCAGCTGGTGGAGTCTGGGAGTGTATGGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGGCTCTCATGGGCAGCCTCTGGATTCACCTTTACTAGCTATTTGATGAGCTGGGTTGGCCAGGCTCCAGGGAAGGGGCTGGAGTGCGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGGACTCTGTGAAGGGCCGATTCACTACTCTCCAGAGACAACGCCAAGAACTCACTGTATGTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGGTCCATCCCCTGGTGGTCCTGTGTGGGGTGACTACTGGGGCCAGGGAATCCTGGTCACCGTCTCCTCAG"], "naive_seq": "NNNGAGGTGCAGCTGGTGGAGTCTGGGGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGACTCTCCTGTGCAGCCTCTGGATTCACCTTTAGTAGCTATTGGATGAGCTGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAGTGGGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGGACTCTGTGAAGGGCCGATTCACCATCTCCAGAGACAACGCCAAGAACTCACTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGGTCCATCCCCTGGTGGTCCTGTGTGGGGTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV3-7*01": 1.0}, "d_per_gene_support": {"IGHD2-8*02": 0.7456845063922822, "IGHD2-15*01": 0.2543154936077163}, "j_per_gene_support": {"IGHJ4*02": 0.999999591826876, "IGHJ5*02": 4.081731325060781e-07}, "v_3p_del": 1, "d_5p_del": 11, "d_3p_del": 12, "j_5p_del": 7, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "GTCCATCCC", "dj_insertion": "CCTGTGTGGGG", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [true], "paired-uids": [["d5ddf0c2ec-igl"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 333}}, {"has_shm_indels": [true, false], "qr_gap_seqs": ["NNNTAGGTGCAGCTGGTGGAGTCTGGAGGAGGCTTGGTCCAGCCTGGGGGTTCCCTGAGACTCTCCTGTGCAACCTCTGGATTCACCTTTAGTAGCTATT.GATGAGCAGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAATGGTTGGCCAACATAAAGTAAGATGGAAGTGAGAAATACTATCTGGACTCTGTGAAGGGCCGACTTACCATCTCCAGAGACAACGCCAAGAACTCACTGTATCTGCAAATGAGCAGCCTGAGAGCCGAGGTCACGGCTGTGTATTACTGTGCGAGAGAGAATTCCGCTAGTGGACCTGTTATCGGTGACTCCTGGGGCCAGGGATTCCTGGTCTCCGTCTCCTCAG", ""], "gl_gap_seqs": ["NNNGAGGTGCAGCTGGTGGAGTCTGGGGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGACTCTCCTGTGCAGCCTCTGGATTCACCTTTAGTAGCTATTGGATGAGCTGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAGTGGGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGGACTCTGTGAAGGGCCGATTCACCATCTCCAGAGACAACGCCAAGAACTCACTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGAGGGTCCCGCCAGTGCACCTGATACCGGTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", ""], "indel_reversed_seqs": ["NNNTAGGTGCAGCTGGTGGAGTCTGGAGGAGGCTTGGTCCAGCCTGGGGGTTCCCTGAGACTCTCCTGTGCAACCTCTGGATTCACCTTTAGTAGCTATTGGATGAGCAGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAATGGTTGGCCAACATAAAGTAAGATGGAAGTGAGAAATACTATCTGGACTCTGTGAAGGGCCGACTTACCATCTCCAGAGACAACGCCAAGAACTCACTGTATCTGCAAATGAGCAGCCTGAGAGCCGAGGTCACGGCTGTGTATTACTGTGCGAGAGAGAATTCCGCTAGTGGACCTGTTATCGGTGACTCCTGGGGCCAGGGATTCCTGGTCTCCGTCTCCTCAG", ""], "unique_ids": ["21cea6e4d0-igh", "57537e5f22-igh"], "invalid": false, "v_gene": "IGHV3-7*01", "d_gene": "IGHD3-16*03", "j_gene": "IGHJ4*02", "cdr3_length": 48, "mut_freqs": [0.06593406593406594, 0.06318681318681318], "n_mutations": [24, 23], "input_seqs": ["NNNTAGGTGCAGCTGGTGGAGTCTGGAGGAGGCTTGGTCCAGCCTGGGGGTTCCCTGAGACTCTCCTGTGCAACCTCTGGATTCACCTTTAGTAGCTATTGATGAGCAGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAATGGTTGGCCAACATAAAGTAAGATGGAAGTGAGAAATACTATCTGGACTCTGTGAAGGGCCGACTTACCATCTCCAGAGACAACGCCAAGAACTCACTGTATCTGCAAATGAGCAGCCTGAGAGCCGAGGTCACGGCTGTGTATTACTGTGCGAGAGAGAATTCCGCTAGTGGACCTGTTATCGGTGACTCCTGGGGCCAGGGATTCCTGGTCTCCGTCTCCTCAG", "NNNTAGGTGCAGCTTGTGGAGTCTGGAGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGACTCTCATGTGCAGCCTCTCGATTCACCTTTAGTAGCTATTGGATGAGCTGGGTCCGCCAGGGTCCAGGGAAGGGGCTGGAGTGGGTGGCCGAGATAAAGCAAGATGGTAGTCAGAAATACTATCTGGACTCACTGAAGGGCCGATTCACCAACTCCAGAGACAACGCCAAGACCTCACTGTATCTGCAAATGAGCAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGGGGGTCCCGCCATTGCAACTGACACCGGTGACTACTGGGGCCAGGCAATCCTGGGCACCGTCTCCTCAG"], "naive_seq": "NNNGAGGTGCAGCTGGTGGAGTCTGGGGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGACTCTCCTGTGCAGCCTCTGGATTCACCTTTAGTAGCTATTGGATGAGCTGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAGTGGGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGGACTCTGTGAAGGGCCGATTCACCATCTCCAGAGACAACGCCAAGAACTCACTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGAGGGTCCCGCCAGTGCACCTGATACCGGTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[], []], "leader_seqs": ["", ""], "c_gene_seqs": ["", ""], "v_per_gene_support": {"IGHV3-7*01": 1.0}, "d_per_gene_support": {"IGHD3-16*03": 0.7677680346276209, "IGHD1-1*01": 0.23028015877168076, "IGHD6-6*01": 0.0012800212115014128, "IGHD1-26*01": 0.0006717853892368645}, "j_per_gene_support": {"IGHJ4*02": 0.9999992505751117, "IGHJ5*02": 7.494248813636061e-07}, "v_3p_del": 0, "d_5p_del": 32, "d_3p_del": 0, "j_5p_del": 7, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "GGGTCCCGCCAGTGCACCTG", "dj_insertion": "GG", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false, false], "in_frames": [false, true], "stops": [true, true], "paired-uids": [["21cea6e4d0-igl"], ["57537e5f22-igl"]], "loci": ["igh", "igh"], "codon_positions": {"v": 288, "j": 333}}, {"has_shm_indels": [true], "qr_gap_seqs": ["CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCAGTGTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACCCCCAACTGGGGACGTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG"], "gl_gap_seqs": ["CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATC....TCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACCCCCAACTGGGGACGTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG"], "indel_reversed_seqs": ["CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACCCCCAACTGGGGACGTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG"], "unique_ids": ["cfe3b29587-igh"], "invalid": false, "v_gene": "IGHV2-70*01", "d_gene": "IGHD7-27*01", "j_gene": "IGHJ4*02", "cdr3_length": 39, "mut_freqs": [0.0], "n_mutations": [0], "input_seqs": ["CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCAGTGTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACCCCCAACTGGGGACGTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG"], "naive_seq": "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACCCCCAACTGGGGACGTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV2-70*01": 1.0}, "d_per_gene_support": {"IGHD7-27*01": 0.9993476455881649, "IGHD1-1*01": 0.0006523544118351107}, "j_per_gene_support": {"IGHJ4*02": 0.9999984857866788, "IGHJ5*02": 1.514213320570988e-06}, "v_3p_del": 0, "d_5p_del": 2, "d_3p_del": 0, "j_5p_del": 7, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "CCCC", "dj_insertion": "CGT", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [false], "stops": [true], "paired-uids": [["09f5010bd3-igl"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 324}}, {"has_shm_indels": [false], "qr_gap_seqs": [""], "gl_gap_seqs": [""], "indel_reversed_seqs": [""], "unique_ids": ["bc11af4843-igh"], "invalid": false, "v_gene": "IGHV2-70*01", "d_gene": "IGHD2-2*01", "j_gene": "IGHJ4*02", "cdr3_length": 39, "mut_freqs": [0.05865921787709497], "n_mutations": [21], "input_seqs": ["CAGGTCAGCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTGTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCAAGGGAAGGCCCTGGAGTGGCTTGCCCTCATTGATTGGGATGATCATAAATACTACAGCAGGACTGTGAAGACCAGGCTCACCATCTTCCAGTACACCTCCAGAAAACAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACTATGCAGAGTCAGCTTTGATTGCTGGGGCCAGGGAAGCCTGGTCACCGTGTCCCCAG"], "naive_seq": "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACTATGCCGAGTCAACTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV2-70*01": 1.0}, "d_per_gene_support": {"IGHD2-2*01": 0.5527021321579755, "IGHD2-8*01": 0.3428150937549728, "IGHD2-8*02": 0.10448277408704772}, "j_per_gene_support": {"IGHJ4*02": 0.9999953481550304, "IGHJ5*02": 4.65184495817866e-06}, "v_3p_del": 0, "d_5p_del": 25, "d_3p_del": 0, "j_5p_del": 3, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "", "dj_insertion": "GAGTCA", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [false], "paired-uids": [["eee6809ad6-igl"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 324}}]}
1
+ {"version-info": {"partis-yaml": 0.1, "partis-git": ""}, "germline-info": {"locus": "igh", "functionalities": {}, "seqs": {"v": {"IGHV1-2*02": "CAGGTGCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGGCCTCAGTGAAGGTCTCCTGCAAGGCTTCTGGATACACCTTCACCGGCTACTATATGCACTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGATGGATCAACCCTAACAGTGGTGGCACAAACTATGCACAGAAGTTTCAGGGCAGGGTCACCATGACCAGGGACACGTCCATCAGCACAGCCTACATGGAGCTGAGCAGGCTGAGATCTGACGACACGGCCGTGTATTACTGTGCGAGAGA", "IGHV1-69*04": "CAGGTCCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGTCCTCGGTGAAGGTCTCCTGCAAGGCTTCTGGAGGCACCTTCAGCAGCTATGCTATCAGCTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGAAGGATCATCCCTATCCTTGGTATAGCAAACTACGCACAGAAGTTCCAGGGCAGAGTCACGATTACCGCGGACAAATCCACGAGCACAGCCTACATGGAGCTGAGCAGCCTGAGATCTGAGGACACGGCCGTGTATTACTGTGCGAGAGA", "IGHV2-70*01": "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATAC", "IGHV3-33*01": "CAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGA", "IGHV3-7*01": "GAGGTGCAGCTGGTGGAGTCTGGGGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGACTCTCCTGTGCAGCCTCTGGATTCACCTTTAGTAGCTATTGGATGAGCTGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAGTGGGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGGACTCTGTGAAGGGCCGATTCACCATCTCCAGAGACAACGCCAAGAACTCACTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGA", "IGHV4-39*01": "CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGAAGCCTTCGGAGACCCTGTCCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACTGGGGCTGGATCCGCCAGCCCCCAGGGAAGGGGCTGGAGTGGATTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCCGTCCCTCAAGAGTCGAGTCACCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGCTCTGTGACCGCCGCAGACACGGCTGTGTATTACTGTGCGAGACA"}, "d": {"IGHD1-1*01": "GGTACAACTGGAACGAC", "IGHD1-14*01": "GGTATAACCGGAACCAC", "IGHD1-26*01": "GGTATAGTGGGAGCTACTAC", "IGHD2-21*01": "AGCATATTGTGGTGGTGATTGCTATTCC", "IGHD3-10*03": "GTATTACTATGGTTCAGGGAGTTATTATAAC", "IGHD3-16*03": "GTATTATGATTACATTTGGGGGAGTTATCGTTATACC", "IGHD3-3*01": "GTATTACGATTTTTGGAGTGGTTATTATACC", "IGHD6-19*01": "GGGTATAGCAGTGGCTGGTAC", "IGHD6-6*01": "GAGTATAGCAGCTCGTCC", "IGHD2-15*01": "AGGATATTGTAGTGGTGGTAGCTGCTACTCC", "IGHD2-2*01": "AGGATATTGTAGTAGTACCAGCTGCTATGCC", "IGHD2-8*01": "AGGATATTGTACTAATGGTGTATGCTATACC", "IGHD2-8*02": "AGGATATTGTACTGGTGGTGTATGCTATACC", "IGHD3-9*01": "GTATTACGATATTTTGACTGGTTATTATAAC", "IGHD7-27*01": "CTAACTGGGGA"}, "j": {"IGHJ3*02": "TGATGCTTTTGATATCTGGGGCCAAGGGACAATGGTCACCGTCTCTTCAG", "IGHJ4*02": "ACTACTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "IGHJ5*02": "ACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "IGHJ6*02": "ATTACTACTACTACTACGGTATGGACGTCTGGGGCCAAGGGACCACGGTCACCGTCTCCTCAG"}}, "cyst-positions": {"IGHV1-69*04": 285, "IGHV1-2*02": 285, "IGHV3-33*01": 285, "IGHV2-70*01": 288, "IGHV3-7*01": 285, "IGHV4-39*01": 288}, "tryp-positions": {"IGHJ4*02": 14, "IGHJ3*02": 16, "IGHJ6*02": 29, "IGHJ5*02": 17}}, "partitions": [{"logprob": 0.0, "n_clusters": 27, "n_procs": 1, "partition": [["28f6e090f2-igh", "584ba32878-igh"], ["3a07b6f0a9-igh", "f3509e0ef3-igh"], ["4f03967793-igh", "6577576bb8-igh", "6cf028b770-igh", "c0fcfe005f-igh", "c2cc9da0c3-igh"], ["7c67587674-igh", "cdae60eacc-igh"], ["8b9ef6b10e-igh"], ["a4b090d0be-igh", "e6fa048856-igh"], ["bb82ebe094-igh"], ["be186138e0-igh"], ["09f5010bd3-igh", "eee6809ad6-igh"], ["e11acbe3ab-igh", "eee2c7797d-igh"], ["276733008f-igh"], ["28ce45b82a-igh"], ["3542bd38d8-igh"], ["35fc655801-igh", "7ba384a461-igh", "7d4166ae48-igh"], ["3c5f4c778a-igh"], ["453132f3ab-igh", "7334912e1e-igh", "f094dfd68a-igh", "b997fa9304-igh"], ["665985d2d1-igh", "d1ee7f9ce6-igh"], ["789d880ef2-igh"], ["b9148494e2-igh"], ["253ca59333-igh", "8d79fca804-igh", "a2238f4e9a-igh", "a3baa83300-igh"], ["7588f09c07-igh", "aa25e6c0ce-igh"], ["b739ce37b7-igh"], ["0eb272ee70-igh", "4d37fe487e-igh", "b02ee7754a-igh", "b1e56e40a1-igh", "ddcf0ca433-igh", "9ed10b6475-igh"], ["14195e4958-igh"], ["21cea6e4d0-igh", "57537e5f22-igh"], ["cfe3b29587-igh"], ["bc11af4843-igh"]]}], "events": [{"has_shm_indels": [false, false], "qr_gap_seqs": ["", ""], "gl_gap_seqs": ["", ""], "indel_reversed_seqs": ["", ""], "unique_ids": ["28f6e090f2-igh", "584ba32878-igh"], "invalid": false, "v_gene": "IGHV1-2*02", "d_gene": "IGHD6-6*01", "j_gene": "IGHJ3*02", "cdr3_length": 63, "mut_freqs": [0.0, 0.0], "n_mutations": [0, 0], "input_seqs": ["NNNCAGGTGCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGGCCTCAGTGAAGGTCTCCTGCAAGGCTTCTGGATACACCTTCACCGGCTACTATATGCACTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGATGGATCAACCCTAACAGTGGTGGCACAAACTATGCACAGAAGTTTCAGGGCAGGGTCACCATGACCAGGGACACGTCCATCAGCACAGCCTACATGGAGCTGAGCAGGCTGAGATCTGACGACACGGCCGTGTATTACTGTGCGAGAACCGGACTGCTCTGTATAGCAGCTCGTCCCGATGGTGATGCTTTTGATATCTGGGGCCAAGGGACAATGGTCACCGTCTCTTCAG", "NNNCAGGTGCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGGCCTCAGTGAAGGTCTCCTGCAAGGCTTCTGGATACACCTTCACCGGCTACTATATGCACTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGATGGATCAACCCTAACAGTGGTGGCACAAACTATGCACAGAAGTTTCAGGGCAGGGTCACCATGACCAGGGACACGTCCATCAGCACAGCCTACATGGAGCTGAGCAGGCTGAGATCTGACGACACGGCCGTGTATTACTGTGCGAGAACCGGACTGCTCTGTATAGCAGCTCGTCCCGATGGTGATGCTTTTGATATCTGGGGCCAAGGGACAATGGTCACCGTCTCTTCAG"], "naive_seq": "NNNCAGGTGCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGGCCTCAGTGAAGGTCTCCTGCAAGGCTTCTGGATACACCTTCACCGGCTACTATATGCACTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGATGGATCAACCCTAACAGTGGTGGCACAAACTATGCACAGAAGTTTCAGGGCAGGGTCACCATGACCAGGGACACGTCCATCAGCACAGCCTACATGGAGCTGAGCAGGCTGAGATCTGACGACACGGCCGTGTATTACTGTGCGAGAACCGGACTGCTCTGTATAGCAGCTCGTCCCGATGGTGATGCTTTTGATATCTGGGGCCAAGGGACAATGGTCACCGTCTCTTCAG", "duplicates": [[], []], "leader_seqs": ["", ""], "c_gene_seqs": ["", ""], "v_per_gene_support": {"IGHV1-2*02": 1.0}, "d_per_gene_support": {"IGHD6-6*01": 0.9999998701800279, "IGHD6-19*01": 1.2981997812807179e-07}, "j_per_gene_support": {"IGHJ3*02": 1.0}, "v_3p_del": 2, "d_5p_del": 2, "d_3p_del": 0, "j_5p_del": 0, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "ACCGGACTGCTCT", "dj_insertion": "CGATGG", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false, false], "in_frames": [true, true], "stops": [false, false], "paired-uids": [["28f6e090f2-igk"], []], "loci": ["igh", "igh"], "codon_positions": {"v": 288, "j": 348}}, {"has_shm_indels": [false, false], "qr_gap_seqs": ["", ""], "gl_gap_seqs": ["", ""], "indel_reversed_seqs": ["", ""], "unique_ids": ["3a07b6f0a9-igh", "f3509e0ef3-igh"], "invalid": false, "v_gene": "IGHV3-33*01", "d_gene": "IGHD1-14*01", "j_gene": "IGHJ6*02", "cdr3_length": 54, "mut_freqs": [0.02702702702702703, 0.02972972972972973], "n_mutations": [10, 11], "input_seqs": ["NNNCAGGTGCAGCTGGTGGAATCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACTCTGCTGTGCAGCGTCTGGATTCACCTTCAGTAGGTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGAGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGTTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGTCACGGCTGTGTATTACTGTGCGAGAGAGCCGGAACCGGAACAAATAGTTGCCTACGGTATGGACGTCTGGGGCCAAGGGACCACGGTCACCGTCTCCTCAG", "NNNCTAGTTCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCTGAATTCACCTTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATCTGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGGGGACACGGCTGTGTATTACTGTGCGAGAGAGCCGACACAGGAACCACGAGTTTGCTACGATATGGACGTCTGGGGCCAAGGGACCACGGTCACCGTCTCCTCAG"], "naive_seq": "NNNCAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGAGCCGGAACCGGAACCACGAGTTGGCTACGGTATGGACGTCTGGGGCCAAGGGACCACGGTCACCGTCTCCTCAG", "duplicates": [[], []], "leader_seqs": ["", ""], "c_gene_seqs": ["", ""], "v_per_gene_support": {"IGHV3-33*01": 1.0}, "d_per_gene_support": {"IGHD1-14*01": 0.9999448576836041, "IGHD1-1*01": 5.514231639909855e-05}, "j_per_gene_support": {"IGHJ6*02": 1.0}, "v_3p_del": 0, "d_5p_del": 5, "d_3p_del": 0, "j_5p_del": 13, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "GCCGG", "dj_insertion": "GAGTTGG", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false, false], "in_frames": [true, true], "stops": [false, false], "paired-uids": [["3a07b6f0a9-igk"], ["f3509e0ef3-igk"]], "loci": ["igh", "igh"], "codon_positions": {"v": 288, "j": 339}}, {"has_shm_indels": [false, true, false, false, false], "qr_gap_seqs": ["", "NNNCAGGTGTAGCTGATGGTGTCTGGGGGAGGCGTGGTCCAGCCTAGGAGGTCCCTGAGACTGACTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGCTATGCCATGCACTGGGTCCGCCAGGCACCCGCCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTATTATATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACCCGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGAATTACTGTGCGAGAGAGGCTGGAGGCGATTTGTGGAATGGTATTTTCGGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "", "", ""], "gl_gap_seqs": ["", "NNNCAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACT..CTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGAGGGCGGGGGCGATTTTTGGAGTGGTTATTATGGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "", "", ""], "indel_reversed_seqs": ["", "NNNCAGGTGTAGCTGATGGTGTCTGGGGGAGGCGTGGTCCAGCCTAGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGCTATGCCATGCACTGGGTCCGCCAGGCACCCGCCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTATTATATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACCCGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGAATTACTGTGCGAGAGAGGCTGGAGGCGATTTGTGGAATGGTATTTTCGGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "", "", ""], "unique_ids": ["4f03967793-igh", "6577576bb8-igh", "6cf028b770-igh", "c0fcfe005f-igh", "c2cc9da0c3-igh"], "invalid": false, "v_gene": "IGHV3-33*01", "d_gene": "IGHD3-3*01", "j_gene": "IGHJ5*02", "cdr3_length": 66, "mut_freqs": [0.060209424083769635, 0.0549738219895288, 0.06806282722513089, 0.034031413612565446, 0.06282722513089005], "n_mutations": [23, 21, 26, 13, 24], "input_seqs": ["NNNCAGGTGCAGCTGATGGTGTCTGGGGGAGGCGGGGTCCAGCCGAGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCGGGATTCACCTTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCACCCGCCAAGGGGCTGGAGTGGGTGGCAATTATATGGTATGATGGAAGTAACAAATACTATGCAGACTCCGTGAAGGGCTGATTCACCATCTCCAGAGACAATTCCAAGAACCCGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGAATTACTGTGCGAGAGAGGGTGGAGGGGATCTCTGGACTGGTCTTTATGGGAACAACTGGTTCGACCCCTGGGGACAGGGAACCCTGGTCACCGTCTCCTCAG", "NNNCAGGTGTAGCTGATGGTGTCTGGGGGAGGCGTGGTCCAGCCTAGGAGGTCCCTGAGACTGACTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGCTATGCCATGCACTGGGTCCGCCAGGCACCCGCCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTATTATATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACCCGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGAATTACTGTGCGAGAGAGGCTGGAGGCGATTTGTGGAATGGTATTTTCGGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "NNNCAGGCGCAGCGGATGGAGTCTGGGGGAGGCGTGGTCCAGCCTAGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCAGGATTCACCTTCAGTAGCTATGGCATGCACCGGGTCCGCCAGGCACCCGCCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATCTTGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACCCGCTGTATCTGCAAATGACAAGCCTGAGAGCCGAGGACACGGATGTGAATTACTGTGCGAGAGATACTGGCGGCGATTTTTCGAATGGCCTTTATGGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "NNNCAGGTGCAGCTGGCGGAGTCTGGGGGAGGCGTGGTCCACCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCATCTGGATTCACCGTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTGCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGAATTACTGTGCGAGAGAGGCCGGGTGAGATTTTGGGTTTGGTTACTATGGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "NNNCAGGTGCAGCTGGTGGGGTCTGGGGGAGGCGTGGTCCAGCCTGGTAGGTCCCTGAGACTCTCCTGTGCAGCGTCTGGATTGACCTTATGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGAGTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAATTGAACAGCTTGAGAGCCGAGGAGACGGCTGTGAATTACTGTCCGAGAGAGGGTGGATTCGAATTATGGATTTGATAGTATGGTACCAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAT"], "naive_seq": "NNNCAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGAGGGCGGGGGCGATTTTTGGAGTGGTTATTATGGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[], [], [], [], []], "leader_seqs": ["", "", "", "", ""], "c_gene_seqs": ["", "", "", "", ""], "v_per_gene_support": {"IGHV3-33*01": 1.0}, "d_per_gene_support": {"IGHD3-3*01": 0.9999999999999716, "IGHD6-19*01": 3.4320278689515095e-14, "IGHD2-21*01": 2.3442754905591374e-15, "IGHD3-10*03": 1.2604117936226715e-16}, "j_per_gene_support": {"IGHJ5*02": 1.0}, "v_3p_del": 0, "d_5p_del": 6, "d_3p_del": 3, "j_5p_del": 0, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "GGGCGGGGG", "dj_insertion": "GGGA", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false, false, false, false, false], "in_frames": [true, false, true, true, true], "stops": [true, true, false, true, true], "paired-uids": [["4f03967793-igk"], ["6577576bb8-igk"], ["6cf028b770-igk"], ["c0fcfe005f-igk"], ["c2cc9da0c3-igk"]], "loci": ["igh", "igh", "igh", "igh", "igh"], "codon_positions": {"v": 288, "j": 351}}, {"has_shm_indels": [false, false], "qr_gap_seqs": ["", ""], "gl_gap_seqs": ["", ""], "indel_reversed_seqs": ["", ""], "unique_ids": ["7c67587674-igh", "cdae60eacc-igh"], "invalid": false, "v_gene": "IGHV3-33*01", "d_gene": "IGHD3-3*01", "j_gene": "IGHJ5*02", "cdr3_length": 66, "mut_freqs": [0.031413612565445025, 0.031413612565445025], "n_mutations": [12, 12], "input_seqs": ["NNNCGGGTGCAGCTGATGGAGTCTGGGGGAGGCGTGGTACAGCCTGGGAGGTCCCTGAGACTCTCCTATGCAGCGTCTGGATTCACCTTCAGTAGCTATGGCATGCACTGGGTCGGCCAGGCTCCCGCCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATGCGCCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGAATTACTGTGCGAGAGAGGCTGGATGCGTTTTTTGGAATGGTCCGTCAAGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "NNNCGGGTGCAGCTGATGGAGTCTGGGGGAGGCGTGGTACAGCCTGGGAGGTCCCTGAGACTCTCCTATGCAGCGTCTGGATTCACCTTCAGTAGCTATGGCATGCACTGGGTCGGCCAGGCTCCCGCCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATGCGCCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGAATTACTGTGCGAGAGAGGCTGGATGCGTTTTTTGGAATGGTCCGTCAAGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG"], "naive_seq": "NNNCAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGAGGCTGGATGCGATTTTTGGAGTGGTCCGTCAAGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[], []], "leader_seqs": ["", ""], "c_gene_seqs": ["", ""], "v_per_gene_support": {"IGHV3-33*01": 1.0}, "d_per_gene_support": {"IGHD3-3*01": 0.9998765244606097, "IGHD6-19*01": 0.000123475539386214}, "j_per_gene_support": {"IGHJ5*02": 1.0}, "v_3p_del": 0, "d_5p_del": 6, "d_3p_del": 9, "j_5p_del": 0, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "GGCTGGATG", "dj_insertion": "CCGTCAAGGA", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false, false], "in_frames": [true, true], "stops": [false, false], "paired-uids": [["7c67587674-igk"], ["cdae60eacc-igk"]], "loci": ["igh", "igh"], "codon_positions": {"v": 288, "j": 351}}, {"has_shm_indels": [false], "qr_gap_seqs": [""], "gl_gap_seqs": [""], "indel_reversed_seqs": [""], "unique_ids": ["8b9ef6b10e-igh"], "invalid": false, "v_gene": "IGHV3-7*01", "d_gene": "IGHD6-6*01", "j_gene": "IGHJ4*02", "cdr3_length": 48, "mut_freqs": [0.04945054945054945], "n_mutations": [18], "input_seqs": ["NNNTAGCTGCAGCTGGCGGAGTCTGGGGGAGGCTTGGTCGAGTCTGGGGGGTCCATGAGACTCTCCTGTGCAGCCTCTGGATTCACCTTTAGTAGTTTTTGGATGAGCTGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAGTGGGTGGCCAACATTAAGCAAGATGGAAGTGAGAAATTCTATGTGGACTCTGTGAAGGGCCGATTCACCATCTCCAGAGACAACGCCAAGAACTAACTGTATCTGCAAATGAACACCCTGAAAGCCGAGGACACGGCTGTGTATTATTGTGCGAGAGAGCGTTCAGCTCGGGGACATGAGCGGGCTGACTAGTGGGGCCAGGGAATCCTTGTCACCGTCTCCACAG"], "naive_seq": "NNNGAGGTGCAGCTGGTGGAGTCTGGGGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGACTCTCCTGTGCAGCCTCTGGATTCACCTTTAGTAGCTATTGGATGAGCTGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAGTGGGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGGACTCTGTGAAGGGCCGATTCACCATCTCCAGAGACAACGCCAAGAACTCACTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGAGCGTTCAGCTCGGGGACATGAGCGGGCTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV3-7*01": 1.0}, "d_per_gene_support": {"IGHD6-6*01": 0.9566124162807413, "IGHD3-10*03": 0.04338758371926616}, "j_per_gene_support": {"IGHJ4*02": 0.999911496238816, "IGHJ5*02": 8.850376117703826e-05}, "v_3p_del": 0, "d_5p_del": 8, "d_3p_del": 3, "j_5p_del": 7, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "GCGTT", "dj_insertion": "GGGACATGAGCGGGC", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [true], "paired-uids": [["51c4c0cd70-igk"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 333}}, {"has_shm_indels": [false, false], "qr_gap_seqs": ["", ""], "gl_gap_seqs": ["", ""], "indel_reversed_seqs": ["", ""], "unique_ids": ["a4b090d0be-igh", "e6fa048856-igh"], "invalid": false, "v_gene": "IGHV2-70*01", "d_gene": "IGHD3-10*03", "j_gene": "IGHJ4*02", "cdr3_length": 39, "mut_freqs": [0.06983240223463687, 0.05307262569832402], "n_mutations": [25, 19], "input_seqs": ["CCGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCTCTCAGCACTAGTGGCATGTGTGTGAGCTGGATCCGTCAGCCCGCAGGGCAGGCCCAGGAGGGGCTTGGACTCATTGATTGGGATGATCATAAATACTACAGCACATCTCTGAAGAACAGACTTACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGATACAGTAACGTATTACTGTGGACGGATACCCTCAATCGTGTACTTGGATTTCTGGGCCCAGGGAACCCTGGTAACCGTCTCCTCAG", "CAGGTCATCTCGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGAACTGCACCTTCTCTGGGTTCTCACTCAGCACGAGTGGAATGTGTGTGAGCTTGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTTCACTCATAGATTGGGATGATCATAAATACTACAGCAAATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACGCCCAAAAACCAGGTGGTCCTTACAATGACCAACATGTACCCTGTGGACAAAGCCACGTCTTACTGTGCACGGATACCTACTATGGTGGAATTTGAACACTGGGGCCAGGGAACCCTGGTCAGCGTCTCCTCAG"], "naive_seq": "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACCTACTATGGTGTACTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[], []], "leader_seqs": ["", ""], "c_gene_seqs": ["", ""], "v_per_gene_support": {"IGHV2-70*01": 1.0}, "d_per_gene_support": {"IGHD3-10*03": 0.9974885981957974, "IGHD6-6*01": 0.0021294073856666707, "IGHD3-16*03": 0.00038199441852192006}, "j_per_gene_support": {"IGHJ4*02": 0.9999974267235101, "IGHJ5*02": 2.5732764872673896e-06}, "v_3p_del": 0, "d_5p_del": 4, "d_3p_del": 18, "j_5p_del": 2, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "C", "dj_insertion": "G", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false, false], "in_frames": [true, true], "stops": [false, false], "paired-uids": [["a4b090d0be-igk"], ["e6fa048856-igk"]], "loci": ["igh", "igh"], "codon_positions": {"v": 288, "j": 324}}, {"has_shm_indels": [false], "qr_gap_seqs": [""], "gl_gap_seqs": [""], "indel_reversed_seqs": [""], "unique_ids": ["bb82ebe094-igh"], "invalid": false, "v_gene": "IGHV2-70*01", "d_gene": "IGHD3-3*01", "j_gene": "IGHJ4*02", "cdr3_length": 39, "mut_freqs": [0.08659217877094973], "n_mutations": [31], "input_seqs": ["CAGGTCACCTTGAGGGAGTTTGGTCCTGCGCTGGTGAAATCCAGACAGATCCTCACCGTGACCTGGACCTTCTCTGGGTTCTCACTCGGCACTAATGGAATGTGTGTGAGCTGGAACCGTCAGCCCCCAGGAAAGGCCATGGAGTGGCTTGGACGCATTGATTGGGATGAGCATAAATACTACAGCACATCGCTGAAAAGCAGGCTCACCATCTCCAAGGACACCTCCAAACACCGGGTGGTCCTTACAATGACCAACATGAACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACTATTGATTTTAGAACTTGATTACTGGGGCTAGGGAACCCTGTTCACCGTCTCCTCAG"], "naive_seq": "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACTGTGGTTATTATACCTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV2-70*01": 1.0}, "d_per_gene_support": {"IGHD3-3*01": 0.9878150009065207, "IGHD3-10*03": 0.00875125776113546, "IGHD3-16*03": 0.0034337413323392097}, "j_per_gene_support": {"IGHJ4*02": 0.9998774786832371, "IGHJ5*02": 0.00012252131675115103}, "v_3p_del": 0, "d_5p_del": 17, "d_3p_del": 0, "j_5p_del": 6, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "T", "dj_insertion": "", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [true], "paired-uids": [["bb82ebe094-igk"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 324}}, {"has_shm_indels": [false], "qr_gap_seqs": [""], "gl_gap_seqs": [""], "indel_reversed_seqs": [""], "unique_ids": ["be186138e0-igh"], "invalid": false, "v_gene": "IGHV1-69*04", "d_gene": "IGHD1-26*01", "j_gene": "IGHJ4*02", "cdr3_length": 48, "mut_freqs": [0.0], "n_mutations": [0], "input_seqs": ["NNNCAGGTCCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGTCCTCGGTGAAGGTCTCCTGCAAGGCTTCTGGAGGCACCTTCAGCAGCTATGCTATCAGCTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGAAGGATCATCCCTATCCTTGGTATAGCAAACTACGCACAGAAGTTCCAGGGCAGAGTCACGATTACCGCGGACAAATCCACGAGCACAGCCTACATGGAGCTGAGCAGCCTGAGATCTGAGGACACGGCCGTGTATTACTGTGCGAGGCGTATAGTGGGAGCTACTACTTACTACTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG"], "naive_seq": "NNNCAGGTCCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGTCCTCGGTGAAGGTCTCCTGCAAGGCTTCTGGAGGCACCTTCAGCAGCTATGCTATCAGCTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGAAGGATCATCCCTATCCTTGGTATAGCAAACTACGCACAGAAGTTCCAGGGCAGAGTCACGATTACCGCGGACAAATCCACGAGCACAGCCTACATGGAGCTGAGCAGCCTGAGATCTGAGGACACGGCCGTGTATTACTGTGCGAGGCGTATAGTGGGAGCTACTACTTACTACTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV1-69*04": 1.0}, "d_per_gene_support": {"IGHD1-26*01": 1.0}, "j_per_gene_support": {"IGHJ4*02": 0.9999999997386197, "IGHJ5*02": 2.6137917103419394e-10}, "v_3p_del": 3, "d_5p_del": 1, "d_3p_del": 0, "j_5p_del": 0, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "GC", "dj_insertion": "TT", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [false], "paired-uids": [["be186138e0-igk"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 333}}, {"has_shm_indels": [true, false], "qr_gap_seqs": ["NNNCAGGTCCAGCTGCTGCAGCCTGGGGCTGAGCTGAAGAAGC............TGCAGGTCTCCTGCAAGGCTTCTGGAGGCACGTTCAGCAGCTTTGCTATCAACTGGGTGAGACAGGCCCCTGGACAAGGGCTTAGGGAGGTCAGGTAGGAGTGGATGGGAAGGATCATCCCTATCCGTGGTATAGCAAACTTCGCACAGAAGTTTCAGGGTGGAGTCACGATTCCCGCGGAAAAATCCACGATGCCAGCCTACATGGAGGTAAGCAGCCTTAGATCCGAGGACACGCTCGTGTATTACTGTGAGAGCCACCACGAGTTATGTCATAAAAATTACTTTGACTATTGGGGCCAGGGAACCCTGGTCACCGTTTGCTCAG", ""], "gl_gap_seqs": ["NNNCAGGTCCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGTCCTCGGTGAAGGTCTCCTGCAAGGCTTCTGGAGGCACCTTCAGCAGCTATGCTATCAGCTGGGTGCGACAGGCCCCTGGACAAGGGCTT...............GAGTGGATGGGAAGGATCATCCCTATCCTTGGTATAGCAAACTACGCACAGAAGTTCCAGGGCAGAGTCACGATTACCGCGGACAAATCCACGAGCACAGCCTACATGGAGCTGAGCAGCCTGAGATCTGAGGACACGGCCGTGTATTACTGTGCGAGCCGCCACGCGTTATACCATAAAACTTACTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", ""], "indel_reversed_seqs": ["NNNCAGGTCCAGCTGCTGCAGCCTGGGGCTGAGCTGAAGAAGCCTGGGTCCTCGGTGCAGGTCTCCTGCAAGGCTTCTGGAGGCACGTTCAGCAGCTTTGCTATCAACTGGGTGAGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGAAGGATCATCCCTATCCGTGGTATAGCAAACTTCGCACAGAAGTTTCAGGGTGGAGTCACGATTCCCGCGGAAAAATCCACGATGCCAGCCTACATGGAGGTAAGCAGCCTTAGATCCGAGGACACGCTCGTGTATTACTGTGAGAGCCACCACGAGTTATGTCATAAAAATTACTTTGACTATTGGGGCCAGGGAACCCTGGTCACCGTTTGCTCAG", ""], "unique_ids": ["09f5010bd3-igh", "eee6809ad6-igh"], "invalid": false, "v_gene": "IGHV1-69*04", "d_gene": "IGHD3-16*03", "j_gene": "IGHJ4*02", "cdr3_length": 48, "mut_freqs": [0.09065934065934066, 0.09065934065934066], "n_mutations": [33, 33], "input_seqs": ["NNNCAGGTCCAGCTGCTGCAGCCTGGGGCTGAGCTGAAGAAGCTGCAGGTCTCCTGCAAGGCTTCTGGAGGCACGTTCAGCAGCTTTGCTATCAACTGGGTGAGACAGGCCCCTGGACAAGGGCTTAGGGAGGTCAGGTAGGAGTGGATGGGAAGGATCATCCCTATCCGTGGTATAGCAAACTTCGCACAGAAGTTTCAGGGTGGAGTCACGATTCCCGCGGAAAAATCCACGATGCCAGCCTACATGGAGGTAAGCAGCCTTAGATCCGAGGACACGCTCGTGTATTACTGTGAGAGCCACCACGAGTTATGTCATAAAAATTACTTTGACTATTGGGGCCAGGGAACCCTGGTCACCGTTTGCTCAG", "NNNCAGGTCGAGCTGCTGCAGCCTGGGGCTGAGCTGAAGAAGCCTGGGGCCTCGCTGCAGGTCTCCTGCAAGGCTTCTGGAGGCACGTTCAGCAGCTTTGCTATCAACTGGGTGAGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGAAGGATCATCCCTATCTGTGGTATAGCAAACTTCGCACAGAAGTTTCAGGGTTGAGTCACGATTCCCGCGGAAAAATCCACGATGCCAGCCTACATGGAGCTAAGCAGCCTGAGATCCGAGGACACGGTCGTGTATAACTGTGAGAGCCGCAACACGTTATATCATAAAACTAACTTTGACTATTGGGGCCAGGGAACCCTGGTCACCGTTTCCTCAG"], "naive_seq": "NNNCAGGTCCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGTCCTCGGTGAAGGTCTCCTGCAAGGCTTCTGGAGGCACCTTCAGCAGCTATGCTATCAGCTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGAAGGATCATCCCTATCCTTGGTATAGCAAACTACGCACAGAAGTTCCAGGGCAGAGTCACGATTACCGCGGACAAATCCACGAGCACAGCCTACATGGAGCTGAGCAGCCTGAGATCTGAGGACACGGCCGTGTATTACTGTGCGAGCCGCCACGCGTTATACCATAAAACTTACTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[], []], "leader_seqs": ["", ""], "c_gene_seqs": ["", ""], "v_per_gene_support": {"IGHV1-69*04": 1.0}, "d_per_gene_support": {"IGHD3-16*03": 0.9336685372120426, "IGHD3-3*01": 0.06559880570253067, "IGHD3-9*01": 0.0007326570854398782}, "j_per_gene_support": {"IGHJ4*02": 0.9999999999985789, "IGHJ5*02": 1.4021616982191138e-12}, "v_3p_del": 3, "d_5p_del": 28, "d_3p_del": 0, "j_5p_del": 3, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "CCGCCACG", "dj_insertion": "ATAAAACTT", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false, false], "in_frames": [true, true], "stops": [true, true], "paired-uids": [["cfe3b29587-igk"], ["bc11af4843-igk"]], "loci": ["igh", "igh"], "codon_positions": {"v": 288, "j": 333}}, {"has_shm_indels": [false, false], "qr_gap_seqs": ["", ""], "gl_gap_seqs": ["", ""], "indel_reversed_seqs": ["", ""], "unique_ids": ["e11acbe3ab-igh", "eee2c7797d-igh"], "invalid": false, "v_gene": "IGHV3-7*01", "d_gene": "IGHD2-15*01", "j_gene": "IGHJ4*02", "cdr3_length": 48, "mut_freqs": [0.03296703296703297, 0.04395604395604396], "n_mutations": [12, 16], "input_seqs": ["NNNTAGGTGCAGCCGGTGGAGTCTGGGGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGACTCTCCTGTGCAGCCTCTGGATTCACCTTTACTAGCTATTGGATGAGCTGGGTCCGCCAGGCTCCAGGGAAGTGGCTGGAGTGTGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGGACTCTGTGAAGGGCCGATTCACCAGCTCCAGAGACAACACCAAGAACTCACTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACCCGGCTGTGTATTACTGTGCGAGAGACCAATCTGCTAGTGGTCTTGGGCGGGGTGACTACTGGGGCCAGGGAAGCCTGGTCACCGTCTCCTCAG", "NNNTAGGTGCAGCGGGTGGAGTATGGGGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGACTCTCCTGAGCAGCCTCTGGATTCACCTTTACTAGCTATTGGATGAGCTGGGTCGGCCAGGCTCCAGGGAAGGGGCTGGAGTGTGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGCACTCTGTGAAGGGCCGACTCACCAGCTCCAGAGACAACGCCAAGAACTCACTGTATCTGCAATTGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGAGCAACCGGCTAGTGGTGTTTGGCGGGCTGAATACTGGGGCCAGGGAAGCCTGGTCACCGTCTCCTCAG"], "naive_seq": "NNNGAGGTGCAGCTGGTGGAGTCTGGGGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGACTCTCCTGTGCAGCCTCTGGATTCACCTTTAGTAGCTATTGGATGAGCTGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAGTGGGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGGACTCTGTGAAGGGCCGATTCACCATCTCCAGAGACAACGCCAAGAACTCACTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGACCAACCGGCTAGTGGTGTTGGGCGGGGTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[], []], "leader_seqs": ["", ""], "c_gene_seqs": ["", ""], "v_per_gene_support": {"IGHV3-7*01": 1.0}, "d_per_gene_support": {"IGHD2-15*01": 0.8865071394001133, "IGHD2-8*02": 0.06261714854126509, "IGHD3-3*01": 0.04667483614876748, "IGHD2-8*01": 0.003361237396511689, "IGHD1-26*01": 0.0008396385133238052}, "j_per_gene_support": {"IGHJ4*02": 0.9999999822484825, "IGHJ5*02": 1.7751514197686412e-08}, "v_3p_del": 0, "d_5p_del": 9, "d_3p_del": 14, "j_5p_del": 7, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "CCAACCGGC", "dj_insertion": "TTGGGCGGGG", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false, false], "in_frames": [true, true], "stops": [true, true], "paired-uids": [["db63559ea9-igk"], ["52387a89c7-igk"]], "loci": ["igh", "igh"], "codon_positions": {"v": 288, "j": 333}}, {"has_shm_indels": [false], "qr_gap_seqs": [""], "gl_gap_seqs": [""], "indel_reversed_seqs": [""], "unique_ids": ["276733008f-igh"], "invalid": false, "v_gene": "IGHV2-70*01", "d_gene": "IGHD2-8*01", "j_gene": "IGHJ4*02", "cdr3_length": 39, "mut_freqs": [0.05865921787709497], "n_mutations": [21], "input_seqs": ["CAGGTCACCTTGAGGGCGTCTGGTCCTGCGCTGCTGAAACCCACAAAGACCCTCACACTTACCTGCACCTTCTCTGGGTTCCCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGCGATGATCATAAATATTATACCACATCTCTTAAGACCCGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCCTACATTGACCAACATGGACCCTGTGAACACAGCCACGTATTACTGTGCACGGATACTCTCTACTATTGGTTTTGTTTACTGGGGCCAGGGTACCCTGGTCACCCTCTCCTCAG"], "naive_seq": "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACTCTGTACTAATGGTTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV2-70*01": 1.0}, "d_per_gene_support": {"IGHD2-8*01": 0.9667034825003873, "IGHD1-26*01": 0.033296517499616006}, "j_per_gene_support": {"IGHJ4*02": 1.0}, "v_3p_del": 0, "d_5p_del": 7, "d_3p_del": 12, "j_5p_del": 5, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "TC", "dj_insertion": "", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [false], "paired-uids": [["276733008f-igk"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 324}}, {"has_shm_indels": [false], "qr_gap_seqs": [""], "gl_gap_seqs": [""], "indel_reversed_seqs": [""], "unique_ids": ["28ce45b82a-igh"], "invalid": false, "v_gene": "IGHV1-69*04", "d_gene": "IGHD1-26*01", "j_gene": "IGHJ4*02", "cdr3_length": 48, "mut_freqs": [0.0], "n_mutations": [0], "input_seqs": ["NNNCAGGTCCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGTCCTCGGTGAAGGTCTCCTGCAAGGCTTCTGGAGGCACCTTCAGCAGCTATGCTATCAGCTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGAAGGATCATCCCTATCCTTGGTATAGCAAACTACGCACAGAAGTTCCAGGGCAGAGTCACGATTACCGCGGACAAATCCACGAGCACAGCCTACATGGAGCTGAGCAGCCTGAGATCTGAGGACACGGCCGTGTATTACTGTGCGAGGCGTATAGTGGGAGCTACTACTTACTACTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG"], "naive_seq": "NNNCAGGTCCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGTCCTCGGTGAAGGTCTCCTGCAAGGCTTCTGGAGGCACCTTCAGCAGCTATGCTATCAGCTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGAAGGATCATCCCTATCCTTGGTATAGCAAACTACGCACAGAAGTTCCAGGGCAGAGTCACGATTACCGCGGACAAATCCACGAGCACAGCCTACATGGAGCTGAGCAGCCTGAGATCTGAGGACACGGCCGTGTATTACTGTGCGAGGCGTATAGTGGGAGCTACTACTTACTACTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV1-69*04": 1.0}, "d_per_gene_support": {"IGHD1-26*01": 0.9999999957069079, "IGHD2-15*01": 4.293090340313514e-09}, "j_per_gene_support": {"IGHJ4*02": 0.999999999857998, "IGHJ5*02": 1.4200256428546358e-10}, "v_3p_del": 3, "d_5p_del": 1, "d_3p_del": 0, "j_5p_del": 0, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "GC", "dj_insertion": "TT", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [false], "paired-uids": [["28ce45b82a-igk"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 333}}, {"has_shm_indels": [false], "qr_gap_seqs": [""], "gl_gap_seqs": [""], "indel_reversed_seqs": [""], "unique_ids": ["3542bd38d8-igh"], "invalid": false, "v_gene": "IGHV2-70*01", "d_gene": "IGHD3-3*01", "j_gene": "IGHJ4*02", "cdr3_length": 39, "mut_freqs": [0.0782122905027933], "n_mutations": [28], "input_seqs": ["CCGGTCACCTTGAGGGAGTCTGGTCCCGCGCTGGTTAAACCCACACAGACCCTCACACTGACCTGCAACTTCTCTGGGCTCTCACTCAGCACTAGTGTAATGCGTGTGAGCTGGATCCGTCAGCCCCCAAGGAAGGCCCTGGAGTGGGATGCACTCATTGTTTGGGATGATCATATATACTACAGCACATCTCTGAAGACCAGGCTCACTATCTCCAAGGACACCTCCACAAACCCGGTGGTCCTTACAATGACCAACATGGTCCCTGTGGATACAGCCACGTATTACTGTGCACTGATACTCGCGAATTTGGATTTAGATTACTGGGGCCACGGAACTCTGTTCACCGTCTCCTCAA"], "naive_seq": "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACTCGCGATTTTTGACTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV2-70*01": 1.0}, "d_per_gene_support": {"IGHD3-3*01": 0.6787543160763233, "IGHD3-16*03": 0.3080937839866766, "IGHD3-9*01": 0.01315189993699562}, "j_per_gene_support": {"IGHJ4*02": 0.9999702470345994, "IGHJ5*02": 2.9752965406579544e-05}, "v_3p_del": 0, "d_5p_del": 6, "d_3p_del": 16, "j_5p_del": 3, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "TCG", "dj_insertion": "", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [false], "paired-uids": [["3542bd38d8-igk"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 324}}, {"has_shm_indels": [false, false, false], "qr_gap_seqs": ["", "", ""], "gl_gap_seqs": ["", "", ""], "indel_reversed_seqs": ["", "", ""], "unique_ids": ["35fc655801-igh", "7ba384a461-igh", "7d4166ae48-igh"], "invalid": false, "v_gene": "IGHV2-70*01", "d_gene": "IGHD7-27*01", "j_gene": "IGHJ4*02", "cdr3_length": 39, "mut_freqs": [0.0, 0.0, 0.00558659217877095], "n_mutations": [0, 0, 2], "input_seqs": ["CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACGCCGAACTGGGGACGTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACGCCGAACTGGGGACGTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACCCCCAACTGGGGACGTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG"], "naive_seq": "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACGCCGAACTGGGGACGTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[], [], []], "leader_seqs": ["", "", ""], "c_gene_seqs": ["", "", ""], "v_per_gene_support": {"IGHV2-70*01": 1.0}, "d_per_gene_support": {"IGHD7-27*01": 0.9998556794105843, "IGHD1-1*01": 0.00014412056798953168, "IGHD3-9*01": 2.000214290266751e-07}, "j_per_gene_support": {"IGHJ4*02": 0.9999990543118211, "IGHJ5*02": 9.456881762103001e-07}, "v_3p_del": 0, "d_5p_del": 2, "d_3p_del": 0, "j_5p_del": 7, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "GCCG", "dj_insertion": "CGT", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false, false, false], "in_frames": [true, true, true], "stops": [false, false, false], "paired-uids": [["35fc655801-igk"], ["7ba384a461-igk"], []], "loci": ["igh", "igh", "igh"], "codon_positions": {"v": 288, "j": 324}}, {"has_shm_indels": [false], "qr_gap_seqs": [""], "gl_gap_seqs": [""], "indel_reversed_seqs": [""], "unique_ids": ["3c5f4c778a-igh"], "invalid": false, "v_gene": "IGHV2-70*01", "d_gene": "IGHD1-1*01", "j_gene": "IGHJ4*02", "cdr3_length": 39, "mut_freqs": [0.04748603351955307], "n_mutations": [17], "input_seqs": ["CAGGTCACCTTGAGGGCGTCTGGTCCTCCGCTGCTGAAACCCACAAAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCCCACTCAGCACGAGTGGAATGTGTGTGAGCTGGATCCTTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTCATTGGGATGCTCATAAATACTACAGCACATCTCTGAAGACCAAGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACCTGGACCCTGTGAACACAGCCACGTATTACTGTGCACGGATACTCCCAACTGTCGGTTTTGATTACTGGGGCCAGGGCACCCTGGTCACCCTCTCCTCAA"], "naive_seq": "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACTCCCAACTGTCGGTTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV2-70*01": 1.0}, "d_per_gene_support": {"IGHD1-1*01": 0.488415118115327, "IGHD7-27*01": 0.48029125259610855, "IGHD2-8*02": 0.01633765712142096, "IGHD2-2*01": 0.014955972167129735}, "j_per_gene_support": {"IGHJ4*02": 1.0}, "v_3p_del": 0, "d_5p_del": 4, "d_3p_del": 7, "j_5p_del": 5, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "TCC", "dj_insertion": "TCGGT", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [false], "paired-uids": [["3c5f4c778a-igk"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 324}}, {"has_shm_indels": [false, false, false, false], "qr_gap_seqs": ["", "", "", ""], "gl_gap_seqs": ["", "", "", ""], "indel_reversed_seqs": ["", "", "", ""], "unique_ids": ["453132f3ab-igh", "7334912e1e-igh", "f094dfd68a-igh", "b997fa9304-igh"], "invalid": false, "v_gene": "IGHV3-33*01", "d_gene": "IGHD1-14*01", "j_gene": "IGHJ6*02", "cdr3_length": 54, "mut_freqs": [0.03513513513513514, 0.03783783783783784, 0.032432432432432434, 0.024324324324324326], "n_mutations": [13, 14, 12, 9], "input_seqs": ["NNNCAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACCCTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGCTATGTCATGGACTGGGTCCGCCAGGCACCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGAACAGGCAGCGGAACCAGAACTTTCCTACGGTATAGACGTCTGGGGCCAAGGGACCACGGTCACCGTCTCCTCAG", "NNNCAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTAGGAGGTCCCTGAGACTCTCCTTTTCAGCGTCTGGATTCACCTTCAGTAGGTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCATACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGTTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGTCCCGGCTGTGTATTACTGTGCGAGAGAGCCGGAACTGGTAGCACTAGTTCCCTACGGTATGGACGTCTGGGGCCAAGGGACCACGGTCACCGTCTCCTCAG", "NNNCAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGGTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGGAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGTCACGGCTGTGGATTACTGTGCGAGAGGGCCGGCACCGGAACCGCTACTTACCTACGGTATGGACGTCTGGGGCCAAGGGACCACGGGCACCGTCTCCTCAG", "NNNCTGGTTCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCTGAATTCACCTTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATCTGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGGGGACACGGCTGTGTATTACTGTGCGAGAGAGCCGACACAGGAACCACGAGTTCGCTACGGTATGGACGTCTGGGGCCAAGGGACCACGGTCACCGTCTCCTCAG"], "naive_seq": "NNNCAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGAGCCGGAACCGGAACCACGAGTTTGCTACGGTATGGACGTCTGGGGCCAAGGGACCACGGTCACCGTCTCCTCAG", "duplicates": [[], [], [], []], "leader_seqs": ["", "", "", ""], "c_gene_seqs": ["", "", "", ""], "v_per_gene_support": {"IGHV3-33*01": 1.0}, "d_per_gene_support": {"IGHD1-14*01": 0.9999976766879956, "IGHD1-1*01": 1.6037445435736297e-06, "IGHD6-19*01": 3.624470931209077e-07, "IGHD2-15*01": 3.433366709190294e-07, "IGHD1-26*01": 1.3783696953904691e-08}, "j_per_gene_support": {"IGHJ6*02": 1.0}, "v_3p_del": 0, "d_5p_del": 5, "d_3p_del": 0, "j_5p_del": 13, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "GCCGG", "dj_insertion": "GAGTTTG", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false, false, false, false], "in_frames": [true, true, true, true], "stops": [false, false, false, false], "paired-uids": [["453132f3ab-igk"], ["7334912e1e-igk"], ["f094dfd68a-igk"], []], "loci": ["igh", "igh", "igh", "igh"], "codon_positions": {"v": 288, "j": 339}}, {"has_shm_indels": [false, false], "qr_gap_seqs": ["", ""], "gl_gap_seqs": ["", ""], "indel_reversed_seqs": ["", ""], "unique_ids": ["665985d2d1-igh", "d1ee7f9ce6-igh"], "invalid": false, "v_gene": "IGHV3-33*01", "d_gene": "IGHD6-19*01", "j_gene": "IGHJ5*02", "cdr3_length": 66, "mut_freqs": [0.015706806282722512, 0.01832460732984293], "n_mutations": [6, 7], "input_seqs": ["NNNCAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCACCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCATCTGGATTCACCGTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGAATTACTGTGCGAGAGAGGCTGGGTTAGATTTTGGGTTTGGTTAGTGTGCGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "NNNCAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCACCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCATCTGGATTCACCGTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGAATTACTGTGCGAGAGAGGCTGGGTGAGATTTTGGGTTTGCTTACTATGGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG"], "naive_seq": "NNNCAGGTGCAGCTGGTGGAGTCTGGGGGAGGCGTGGTCCAGCCTGGGAGGTCCCTGAGACTCTCCTGTGCAGCGTCTGGATTCACCTTCAGTAGCTATGGCATGCACTGGGTCCGCCAGGCTCCAGGCAAGGGGCTGGAGTGGGTGGCAGTTATATGGTATGATGGAAGTAATAAATACTATGCAGACTCCGTGAAGGGCCGATTCACCATCTCCAGAGACAATTCCAAGAACACGCTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGAGGCTGGGTGAGATTTTGGGTTTGGTTAGTGTGGGAACAACTGGTTCGACCCCTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[], []], "leader_seqs": ["", ""], "c_gene_seqs": ["", ""], "v_per_gene_support": {"IGHV3-33*01": 1.0}, "d_per_gene_support": {"IGHD6-19*01": 0.5498427718139053, "IGHD3-3*01": 0.4188548198724743, "IGHD3-16*03": 0.028855233142586194, "IGHD3-9*01": 0.002447175171016475}, "j_per_gene_support": {"IGHJ5*02": 1.0}, "v_3p_del": 0, "d_5p_del": 12, "d_3p_del": 3, "j_5p_del": 0, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "", "dj_insertion": "GTGAGATTTTGGGTTTGGTTAGTGTGGGA", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false, false], "in_frames": [true, true], "stops": [true, true], "paired-uids": [["665985d2d1-igk"], ["d1ee7f9ce6-igk"]], "loci": ["igh", "igh"], "codon_positions": {"v": 288, "j": 351}}, {"has_shm_indels": [false], "qr_gap_seqs": [""], "gl_gap_seqs": [""], "indel_reversed_seqs": [""], "unique_ids": ["789d880ef2-igh"], "invalid": false, "v_gene": "IGHV2-70*01", "d_gene": "IGHD3-9*01", "j_gene": "IGHJ4*02", "cdr3_length": 39, "mut_freqs": [0.061452513966480445], "n_mutations": [22], "input_seqs": ["CAGGTCACCTTGAGGGAGTTTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCTCACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCTCTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGGACTCATTTATTGGTATGATCATAAATAATACGGCACATCGCTGAAGAGGAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGATCCTTACAATTACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTTCACGGATACACTAAAGTGTGACTGTTGATTCCTGGGGCCAGGGAACCCTGGTCACCGTATCCTCAG"], "naive_seq": "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACACGATATTTTGACTGTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV2-70*01": 1.0}, "d_per_gene_support": {"IGHD3-9*01": 0.9520465873464513, "IGHD1-26*01": 0.047953412653544795}, "j_per_gene_support": {"IGHJ4*02": 0.9986875587196622, "IGHJ5*02": 0.0013124412803428623}, "v_3p_del": 0, "d_5p_del": 5, "d_3p_del": 11, "j_5p_del": 6, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "", "dj_insertion": "", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [true], "paired-uids": [["789d880ef2-igk"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 324}}, {"has_shm_indels": [false], "qr_gap_seqs": [""], "gl_gap_seqs": [""], "indel_reversed_seqs": [""], "unique_ids": ["b9148494e2-igh"], "invalid": false, "v_gene": "IGHV1-2*02", "d_gene": "IGHD6-6*01", "j_gene": "IGHJ3*02", "cdr3_length": 63, "mut_freqs": [0.0], "n_mutations": [0], "input_seqs": ["NNNCAGGTGCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGGCCTCAGTGAAGGTCTCCTGCAAGGCTTCTGGATACACCTTCACCGGCTACTATATGCACTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGATGGATCAACCCTAACAGTGGTGGCACAAACTATGCACAGAAGTTTCAGGGCAGGGTCACCATGACCAGGGACACGTCCATCAGCACAGCCTACATGGAGCTGAGCAGGCTGAGATCTGACGACACGGCCGTGTATTACTGTGCGAGAACCGGACTGCTCTGTATAGCAGCTCGTCCCGATGGTGATGCTTTTGATATCTGGGGCCAAGGGACAATGGTCACCGTCTCTTCAG"], "naive_seq": "NNNCAGGTGCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGGCCTCAGTGAAGGTCTCCTGCAAGGCTTCTGGATACACCTTCACCGGCTACTATATGCACTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGATGGATCAACCCTAACAGTGGTGGCACAAACTATGCACAGAAGTTTCAGGGCAGGGTCACCATGACCAGGGACACGTCCATCAGCACAGCCTACATGGAGCTGAGCAGGCTGAGATCTGACGACACGGCCGTGTATTACTGTGCGAGAACCGGACTGCTCTGTATAGCAGCTCGTCCCGATGGTGATGCTTTTGATATCTGGGGCCAAGGGACAATGGTCACCGTCTCTTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV1-2*02": 1.0}, "d_per_gene_support": {"IGHD6-6*01": 0.9999992854308881, "IGHD6-19*01": 6.887629223866832e-07, "IGHD2-15*01": 2.5806183206409083e-08}, "j_per_gene_support": {"IGHJ3*02": 1.0}, "v_3p_del": 2, "d_5p_del": 2, "d_3p_del": 0, "j_5p_del": 0, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "ACCGGACTGCTCT", "dj_insertion": "CGATGG", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [false], "paired-uids": [["b9148494e2-igk"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 348}}, {"has_shm_indels": [false, false, true, false], "qr_gap_seqs": ["", "", "CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTGTTCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACAGGGGCTCGATCCGCCAGCCCCCAAGTAAGGGGCTGGAGTGGATTGGGAGTATCTATTATAGTGTGAGCACC.ACTACAACCAGTCTCTCAAGAGTCGAGTCTCCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAACTGAGCTCTGTGACTCCCGCAGAAACGGCGGCGTATTACTGTGCGAGAAAGCAAAGCGACACAGTACCCCCCACTGTCCTCGAACGGGACTACTGGGGCCAGGGAACCCTGGTTACCGTCTCCTCAG", ""], "gl_gap_seqs": ["", "", "CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGAAGCCTTCGGAGACCCTGTCCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACTGGGGCTGGATCCGCCAGCCCCCAGGGAAGGGGCTGGAGTGGATTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCCGTCCCTCAAGAGTCGAGTCACCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGCTCTGTGACCGCCGCAGACACGGCTGTGTATTACTGTGCGAGCGAGCCAAGTATAGCAGTACCCCCCACGACCCTCGGGCGGGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", ""], "indel_reversed_seqs": ["", "", "CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTGTTCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACAGGGGCTCGATCCGCCAGCCCCCAAGTAAGGGGCTGGAGTGGATTGGGAGTATCTATTATAGTGTGAGCACCTACTACAACCAGTCTCTCAAGAGTCGAGTCTCCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAACTGAGCTCTGTGACTCCCGCAGAAACGGCGGCGTATTACTGTGCGAGAAAGCAAAGCGACACAGTACCCCCCACTGTCCTCGAACGGGACTACTGGGGCCAGGGAACCCTGGTTACCGTCTCCTCAG", ""], "unique_ids": ["253ca59333-igh", "8d79fca804-igh", "a2238f4e9a-igh", "a3baa83300-igh"], "invalid": false, "v_gene": "IGHV4-39*01", "d_gene": "IGHD6-19*01", "j_gene": "IGHJ4*02", "cdr3_length": 57, "mut_freqs": [0.06914893617021277, 0.06914893617021277, 0.08244680851063829, 0.07180851063829788], "n_mutations": [26, 26, 31, 27], "input_seqs": ["CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTGTCCCTCACCTGCACTGTCTCTGTTGGCTCCATCAGCAGAAGTAGTTACTACTGCGGCCCGATCCGCCAGCCCCCAGGTAAGGGGCTGGAGTGGATTCGGAGTATCTATTATAGTGGGAGCACCTACTACATCCAGTCCCTCAAGAGTCGAGTCACCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGCTCTGTGACCGCCGCAGACACGGCTGCGTATTACTGTGCGAGCCAACCATGCATATCAGTACCTCCTACTAAACTCTCGCAAGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "CAGCTGCAGCAGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTATCCCTCACCTGCACTGGCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACAGGGGCTCGATCCGCCAGCCCCCAGGTAAGGGGCTGGAGTGGATTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCAGTCCCTCAAGAGTCGAGTCTCCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGGTCTGTGACCGCGGCAGACACGGCTGCGTATTACTGTGCGAGCGAGCAATGTAAAACAGTACCTCCTACTTCCATCGGTCGAGACTACTGGGGCCAGGGAACCCTGGTTCCCGTCTCCTCAG", "CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTGTTCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACAGGGGCTCGATCCGCCAGCCCCCAAGTAAGGGGCTGGAGTGGATTGGGAGTATCTATTATAGTGTGAGCACCACTACAACCAGTCTCTCAAGAGTCGAGTCTCCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAACTGAGCTCTGTGACTCCCGCAGAAACGGCGGCGTATTACTGTGCGAGAAAGCAAAGCGACACAGTACCCCCCACTGTCCTCGAACGGGACTACTGGGGCCAGGGAACCCTGGTTACCGTCTCCTCAG", "CAGCTGCAGCAGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTATCCCTCACCTGCACTGGCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACAGGGGCTCGATCCGCCAGCCCCCAGGTAAGGGGCTGGAGTGGATTGGGAGTATCTATTAAAGTGGGAGCACCTACTACAACCAGTCCCTCAAGAGTCGAGTCTCCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGGTCTGTGACCGCGGCAGACACGGCTGCGTATTACTGTGCGAGCTAGCAATGTAAAACAGTACCTCCTACGTCCATCGGTCGAGACTACTGGGGCCAGGGAACCCTGGTTCCCGTCTCCTCAG"], "naive_seq": "CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGAAGCCTTCGGAGACCCTGTCCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACTGGGGCTGGATCCGCCAGCCCCCAGGGAAGGGGCTGGAGTGGATTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCCGTCCCTCAAGAGTCGAGTCACCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGCTCTGTGACCGCCGCAGACACGGCTGTGTATTACTGTGCGAGCGAGCCAAGTATAGCAGTACCCCCCACGACCCTCGGGCGGGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[], [], [], []], "leader_seqs": ["", "", "", ""], "c_gene_seqs": ["", "", "", ""], "v_per_gene_support": {"IGHV4-39*01": 1.0}, "d_per_gene_support": {"IGHD6-19*01": 0.9833480536021382, "IGHD6-6*01": 0.015956577558223453, "IGHD1-1*01": 0.0006953688396342909}, "j_per_gene_support": {"IGHJ4*02": 0.999982268710881, "IGHJ5*02": 1.7731289131899734e-05}, "v_3p_del": 3, "d_5p_del": 2, "d_3p_del": 9, "j_5p_del": 8, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "CGAGCCAA", "dj_insertion": "ACCCCCCACGACCCTCGGGCGG", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false, false, false, false], "in_frames": [true, true, false, true], "stops": [false, false, true, true], "paired-uids": [["253ca59333-igl"], ["8d79fca804-igl"], ["a2238f4e9a-igl"], ["a3baa83300-igl"]], "loci": ["igh", "igh", "igh", "igh"], "codon_positions": {"v": 288, "j": 342}}, {"has_shm_indels": [false, false], "qr_gap_seqs": ["", ""], "gl_gap_seqs": ["", ""], "indel_reversed_seqs": ["", ""], "unique_ids": ["7588f09c07-igh", "aa25e6c0ce-igh"], "invalid": false, "v_gene": "IGHV4-39*01", "d_gene": "IGHD6-19*01", "j_gene": "IGHJ4*02", "cdr3_length": 57, "mut_freqs": [0.05319148936170213, 0.061170212765957445], "n_mutations": [20, 23], "input_seqs": ["CAGCTGCAGCTGCAGGAGTCGAGCCCAGGACTGGTGATGCCTTCGGAGACCTTGTCCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACTGGGGCTGGATCCGCCAGCCCCCAGGTAAGGGGCTGGAGTGGCTTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCAGTCAGTCAAGAGTCGAGTCACCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGATGAGCTCTGTGACCGCCGCAGACACGGCTGCGTATTACTGTGCGAGCCCTCCTTGGATAGCAGGGCTTCGTTCAAAGATAGCACTAGACTACTGGGACCAGGGAACCCTGGTCACCGTCTCCTCAG", "CAGCTGCAGCTGCAGGAGTCGAGCCCAGGACTGGTGATGCCTTCGGAGACCTTGTCCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACGACTGGGGCTTGATCCGCCAGCCCCCAGGTAAGGGGCTGGAGTGGCTTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCAGTCCCTCAAGAGTCGATTCACCATATCCGTAGACCCGTCCAAGAACCAGTTCTCCCTGAAGCTGCGCTCTGTGACCGCCGCAGACACGGCTGCGTATTACTGTGCGAGCAAACATTGAATAGCAGTATCTAGTACTTCGATAGCACCGGACTACTGGGACAAGGGAACCCTGGTCACCGTCTCCTCAG"], "naive_seq": "CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGAAGCCTTCGGAGACCCTGTCCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACTGGGGCTGGATCCGCCAGCCCCCAGGGAAGGGGCTGGAGTGGATTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCCGTCCCTCAAGAGTCGAGTCACCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGCTCTGTGACCGCCGCAGACACGGCTGTGTATTACTGTGCGAGCCCACCTTGGATAGCAGTGGCTGGTACAACGATAGCACCGGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[], []], "leader_seqs": ["", ""], "c_gene_seqs": ["", ""], "v_per_gene_support": {"IGHV4-39*01": 1.0}, "d_per_gene_support": {"IGHD6-19*01": 0.9999979095272203, "IGHD6-6*01": 2.090456509010692e-06, "IGHD1-26*01": 1.6260047500959325e-11}, "j_per_gene_support": {"IGHJ4*02": 0.9999982940214863, "IGHJ5*02": 1.705978509508022e-06}, "v_3p_del": 3, "d_5p_del": 4, "d_3p_del": 0, "j_5p_del": 8, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "CCCACCTTGG", "dj_insertion": "AACGATAGCACCG", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false, false], "in_frames": [true, true], "stops": [false, true], "paired-uids": [["7588f09c07-igl"], ["aa25e6c0ce-igl"]], "loci": ["igh", "igh"], "codon_positions": {"v": 288, "j": 342}}, {"has_shm_indels": [false], "qr_gap_seqs": [""], "gl_gap_seqs": [""], "indel_reversed_seqs": [""], "unique_ids": ["b739ce37b7-igh"], "invalid": false, "v_gene": "IGHV1-69*04", "d_gene": "IGHD2-21*01", "j_gene": "IGHJ4*02", "cdr3_length": 48, "mut_freqs": [0.07692307692307693], "n_mutations": [28], "input_seqs": ["NNNCAGGTCCAGCTGATGCAGTCTTGGGCTGAGCTGAAGAAGCCTGTGTCCTCGCTGAAGGTCTCCTGCAAGGCTTCTGGAGGCACCTTCAGCAGCTAAGATATCAACTGTGTGCGACAGGCCCCTGGACAGGGGCTTGAGTGGATGGGAAGGATCATCCCTATCCTTGGTATAGCAAACATCGCACAGAAGTTCCACGGCAGAGTCACGATTCCCGTGGAAATATACACGATGACAGCCTACATGGAGCTGAGCAGCATGAGATCCGGGGACACGGCCGTGTATTACTGTGGGAGATGACGGGAGGGAGATGGTGTTGATTACTTTGACTATTGGGGCCAGGGAACCCTGGTCACCGTCTTCTCAC"], "naive_seq": "NNNCAGGTCCAGCTGGTGCAGTCTGGGGCTGAGGTGAAGAAGCCTGGGTCCTCGGTGAAGGTCTCCTGCAAGGCTTCTGGAGGCACCTTCAGCAGCTATGCTATCAGCTGGGTGCGACAGGCCCCTGGACAAGGGCTTGAGTGGATGGGAAGGATCATCCCTATCCTTGGTATAGCAAACTACGCACAGAAGTTCCAGGGCAGAGTCACGATTACCGCGGACAAATCCACGAGCACAGCCTACATGGAGCTGAGCAGCCTGAGATCTGAGGACACGGCCGTGTATTACTGTGCGAGATGACGGGAGGGAGATGGTGGTGATTACTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV1-69*04": 1.0}, "d_per_gene_support": {"IGHD2-21*01": 1.0}, "j_per_gene_support": {"IGHJ4*02": 1.0}, "v_3p_del": 2, "d_5p_del": 9, "d_3p_del": 9, "j_5p_del": 2, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "TGACGGGAGGGAGA", "dj_insertion": "", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [true], "paired-uids": [["b739ce37b7-igl"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 333}}, {"has_shm_indels": [false, false, true, true, false, false], "qr_gap_seqs": ["", "", "CAGCTGCAGCAGCAGGAGTCGGGCCCAAGGGACTGGTGATGCCTTCGGAGACCTTATCCCTCACCTGCACTGGCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACAGGGGCTCGATCCGCCAGCCCCCAGGTAAGGGGCTGGACTGGATTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCAGTCTCTCAAGAGTCGAGTCTCCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGGTCTGTGACCGCGGCAGACACGGCTGCGTATTACTGTGCGAGCGAGCAATGTAAAACAGTACCTCCTACTTCCATCGCTCGCGACTACTGGGGCCAGGGAACCCTGGTTCCCGTCTCCTCAG", "CAGCTGCAGCAGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTATCCCTCACCTGCACTGGCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACAGGGGCTCGATCCGCCAGACCCCAGGTAAGGGGCTGGAGTGGATTGGGACTATCTATTACATTACTGGGAGCACCTACTACGACCAGTCCCTCAAGAGTCGAGTCTCCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGGTCTGTGACCGCGGCAGACACGGCTGCGTATTACTGTGCGAGCGAGCAATGTAAAACAGTACCACCTACTTCCATCGCTCGAGACTTCTGGGGCCAGGGAACCCTGGTTCCCGTCTCCTCAG", "", ""], "gl_gap_seqs": ["", "", "CAGCTGCAGCTGCAGGAGTCGGGCCCA..GGACTGGTGAAGCCTTCGGAGACCCTGTCCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACTGGGGCTGGATCCGCCAGCCCCCAGGGAAGGGGCTGGAGTGGATTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCCGTCCCTCAAGAGTCGAGTCACCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGCTCTGTGACCGCCGCAGACACGGCTGTGTATTACTGTGCGAGCCAGCCGTGTATAGCAGTACCTCTTGCTTGGATCGCGCGGGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGAAGCCTTCGGAGACCCTGTCCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACTGGGGCTGGATCCGCCAGCCCCCAGGGAAGGGGCTGGAGTGGATTGGGAGTATCTATTA...TAGTGGGAGCACCTACTACAACCCGTCCCTCAAGAGTCGAGTCACCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGCTCTGTGACCGCCGCAGACACGGCTGTGTATTACTGTGCGAGCCAGCCGTGTATAGCAGTACCTCTTGCTTGGATCGCGCGGGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "", ""], "indel_reversed_seqs": ["", "", "CAGCTGCAGCAGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTATCCCTCACCTGCACTGGCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACAGGGGCTCGATCCGCCAGCCCCCAGGTAAGGGGCTGGACTGGATTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCAGTCTCTCAAGAGTCGAGTCTCCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGGTCTGTGACCGCGGCAGACACGGCTGCGTATTACTGTGCGAGCGAGCAATGTAAAACAGTACCTCCTACTTCCATCGCTCGCGACTACTGGGGCCAGGGAACCCTGGTTCCCGTCTCCTCAG", "CAGCTGCAGCAGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTATCCCTCACCTGCACTGGCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACAGGGGCTCGATCCGCCAGACCCCAGGTAAGGGGCTGGAGTGGATTGGGACTATCTATTATACTGGGAGCACCTACTACGACCAGTCCCTCAAGAGTCGAGTCTCCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGGTCTGTGACCGCGGCAGACACGGCTGCGTATTACTGTGCGAGCGAGCAATGTAAAACAGTACCACCTACTTCCATCGCTCGAGACTTCTGGGGCCAGGGAACCCTGGTTCCCGTCTCCTCAG", "", ""], "unique_ids": ["0eb272ee70-igh", "4d37fe487e-igh", "b02ee7754a-igh", "b1e56e40a1-igh", "ddcf0ca433-igh", "9ed10b6475-igh"], "invalid": false, "v_gene": "IGHV4-39*01", "d_gene": "IGHD6-19*01", "j_gene": "IGHJ4*02", "cdr3_length": 57, "mut_freqs": [0.07180851063829788, 0.08244680851063829, 0.07446808510638298, 0.0851063829787234, 0.06648936170212766, 0.0797872340425532], "n_mutations": [27, 31, 28, 32, 25, 30], "input_seqs": ["CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTGTCCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGAAGTAGTAGTTCCTACTGGGGCCGGATCCGCCAGCCCCCAGGTAAGGGGGTGGAGTGGATTGGGAGTATCTATGATAGTGGTAGCACCTACTATAACCAGTCCCTCAAGAGTCGAGTCACCATATCTGTAGACGCGTCCAAGAAGCAGTTCTCCCTGAAGCTGAGCTCTGTGCCCGCCGCAGACACGGCTGCGTATTACTGTGCGAGAGAGTTGTGTATAGCAGTGCTTCTTGCTTGGATAGCCCCGGACTACTGGGGCTAGGGAACCCTGGTCACCGTCTCCTCTG", "CAGCTGCAGCTGCAGGAGTCGAACCCAGGACTGGTGATGCCTTCGGAGACCTTGTCCCTCACCTGCACTGTCTATGGTGGCTCCATCACCAGTAGTAGTTACTACTGGGGCTGGATCCGCCAGCCCCCAGGTAAGGGGCTGGAGTGGCTTGGGAGTATCTCTTATAGTGGGAGCACATACTACAACCAGTCACTCAAGAGTCGAGTCACCATATCCGTAGACACGTCCATGAACCAGTTCTCCCTGAAGCTGAGCTCTGTCACCGCCGCAGACACGGCTGCGTCTTACTGTGCGAGCCTGCCTAGAAGAGAAGTACCTCTTTATAAGATAGCTCAAGACTACTGGGACCAGGGAACCCTGGTCACCGTCTCCTCAG", "CAGCTGCAGCAGCAGGAGTCGGGCCCAAGGGACTGGTGATGCCTTCGGAGACCTTATCCCTCACCTGCACTGGCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACAGGGGCTCGATCCGCCAGCCCCCAGGTAAGGGGCTGGACTGGATTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCAGTCTCTCAAGAGTCGAGTCTCCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGGTCTGTGACCGCGGCAGACACGGCTGCGTATTACTGTGCGAGCGAGCAATGTAAAACAGTACCTCCTACTTCCATCGCTCGCGACTACTGGGGCCAGGGAACCCTGGTTCCCGTCTCCTCAG", "CAGCTGCAGCAGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTATCCCTCACCTGCACTGGCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACAGGGGCTCGATCCGCCAGACCCCAGGTAAGGGGCTGGAGTGGATTGGGACTATCTATTACATTACTGGGAGCACCTACTACGACCAGTCCCTCAAGAGTCGAGTCTCCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGGTCTGTGACCGCGGCAGACACGGCTGCGTATTACTGTGCGAGCGAGCAATGTAAAACAGTACCACCTACTTCCATCGCTCGAGACTTCTGGGGCCAGGGAACCCTGGTTCCCGTCTCCTCAG", "CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGATGCCTTCGGAGACCTTGTCCCTCACCTGCACTGTCTCTGTTGGCTCCATCAGCAGAAGTAGTTACTACTGCGGCCCGATCCGCCAGCCCCCAGGTAAGGGGCTGGAGTGGATTCGGAGTATCTATTATAGTGGGAGCACCTACTACATCCAGTCCCTCAAGAGTCGAGTCACCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGCTCTGTGACCGCCGCAGACACGGCTGCGTATTACTGTGCGAGCCAGCCTTGCATATCAGTACCTCCTACAAAACTCTCGCAAGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "CAGCTGCAGCTGCAGGAGTCGAGCCCAGGACTGGTGATGCCTTCGGAGACCTTGTCCCTCACCTGCACTGTCTGTGGTGGCTCCATCAGCAGTAGTAGTTACGACTGGGGCTTGATCCGCCAGCCCCCAGGTAAGGGGCTGGAGTGGCTTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCAGTCCCTCAAGAGTCGATTCACCATATCCGTAGAGCCGTCCAAGAACCAGTTCTCCCTGAAGCTGAGCTCTGTGACCGCCGCCGACACGGCTGCGTATTACTGTCCGAGTTAGCTTTGAATAGCAGTCCCTCGTACTTCGATATCACCGGACTACTGGGACAAGGGAACCCTGGTCACCGTCTCCTCAG"], "naive_seq": "CAGCTGCAGCTGCAGGAGTCGGGCCCAGGACTGGTGAAGCCTTCGGAGACCCTGTCCCTCACCTGCACTGTCTCTGGTGGCTCCATCAGCAGTAGTAGTTACTACTGGGGCTGGATCCGCCAGCCCCCAGGGAAGGGGCTGGAGTGGATTGGGAGTATCTATTATAGTGGGAGCACCTACTACAACCCGTCCCTCAAGAGTCGAGTCACCATATCCGTAGACACGTCCAAGAACCAGTTCTCCCTGAAGCTGAGCTCTGTGACCGCCGCAGACACGGCTGTGTATTACTGTGCGAGCCAGCCGTGTATAGCAGTACCTCTTGCTTGGATCGCGCGGGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[], [], [], [], [], []], "leader_seqs": ["", "", "", "", "", ""], "c_gene_seqs": ["", "", "", "", "", ""], "v_per_gene_support": {"IGHV4-39*01": 1.0}, "d_per_gene_support": {"IGHD6-19*01": 0.9369032357955595, "IGHD6-6*01": 0.058574356983753295, "IGHD1-14*01": 0.001326241506365111, "IGHD3-16*03": 0.0011458274120855697, "IGHD2-2*01": 0.0010424013132667286, "IGHD2-15*01": 0.0010078627570677952, "IGHD3-9*01": 7.423186939560802e-08}, "j_per_gene_support": {"IGHJ4*02": 0.9999941657499907, "IGHJ5*02": 5.834250005393095e-06}, "v_3p_del": 3, "d_5p_del": 2, "d_3p_del": 9, "j_5p_del": 8, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "CCAGCCGT", "dj_insertion": "ACCTCTTGCTTGGATCGCGCGG", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false, false, false, false, false, false], "in_frames": [true, true, false, true, true, true], "stops": [true, false, true, false, false, true], "paired-uids": [["0eb272ee70-igl"], ["4d37fe487e-igl"], ["b02ee7754a-igl"], ["b1e56e40a1-igl"], ["ddcf0ca433-igl"], []], "loci": ["igh", "igh", "igh", "igh", "igh", "igh"], "codon_positions": {"v": 288, "j": 342}}, {"has_shm_indels": [true], "qr_gap_seqs": ["NNNTTGGTGCAGCTGGTGGAGTCTGGGAGTGTATGGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGGCTCTCATGGGCAGCCTCTGGATTCACCTTTACTAGCTATTTGATGAGCTGGGTTGGCCAGGCTCCAGGGAAGGGGCTGGAGTGCGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGGACTCTGTGAAGGGCCGATTCACTACTCTCCAGAGACAACGCCAAGAACTCACTGTATGTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGGTCCATCCCCTGGTGGTCCTGTGTGGGGTGACTACTGGGGCCAGGGAATCCTGGTCACCGTCTCCTCAG"], "gl_gap_seqs": ["NNNGAGGTGCAGCTGGTGGAGTCTGG........GGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGACTCTCCTGTGCAGCCTCTGGATTCACCTTTAGTAGCTATTGGATGAGCTGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAGTGGGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGGACTCTGTGAAGGGCCGATTCACCA.TCTCCAGAGACAACGCCAAGAACTCACTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGGTCCATCCCCTGGTGGTCCTGTGTGGGGTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG"], "indel_reversed_seqs": ["NNNTTGGTGCAGCTGGTGGAGTCTGGGGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGGCTCTCATGGGCAGCCTCTGGATTCACCTTTACTAGCTATTTGATGAGCTGGGTTGGCCAGGCTCCAGGGAAGGGGCTGGAGTGCGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGGACTCTGTGAAGGGCCGATTCACTATCTCCAGAGACAACGCCAAGAACTCACTGTATGTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGGTCCATCCCCTGGTGGTCCTGTGTGGGGTGACTACTGGGGCCAGGGAATCCTGGTCACCGTCTCCTCAG"], "unique_ids": ["14195e4958-igh"], "invalid": false, "v_gene": "IGHV3-7*01", "d_gene": "IGHD2-8*02", "j_gene": "IGHJ4*02", "cdr3_length": 48, "mut_freqs": [0.03571428571428571], "n_mutations": [13], "input_seqs": ["NNNTTGGTGCAGCTGGTGGAGTCTGGGAGTGTATGGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGGCTCTCATGGGCAGCCTCTGGATTCACCTTTACTAGCTATTTGATGAGCTGGGTTGGCCAGGCTCCAGGGAAGGGGCTGGAGTGCGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGGACTCTGTGAAGGGCCGATTCACTACTCTCCAGAGACAACGCCAAGAACTCACTGTATGTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGGTCCATCCCCTGGTGGTCCTGTGTGGGGTGACTACTGGGGCCAGGGAATCCTGGTCACCGTCTCCTCAG"], "naive_seq": "NNNGAGGTGCAGCTGGTGGAGTCTGGGGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGACTCTCCTGTGCAGCCTCTGGATTCACCTTTAGTAGCTATTGGATGAGCTGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAGTGGGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGGACTCTGTGAAGGGCCGATTCACCATCTCCAGAGACAACGCCAAGAACTCACTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGGTCCATCCCCTGGTGGTCCTGTGTGGGGTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV3-7*01": 1.0}, "d_per_gene_support": {"IGHD2-8*02": 0.7456845063922822, "IGHD2-15*01": 0.2543154936077163}, "j_per_gene_support": {"IGHJ4*02": 0.999999591826876, "IGHJ5*02": 4.081731325060781e-07}, "v_3p_del": 1, "d_5p_del": 11, "d_3p_del": 12, "j_5p_del": 7, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "GTCCATCCC", "dj_insertion": "CCTGTGTGGGG", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [true], "paired-uids": [["d5ddf0c2ec-igl"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 333}}, {"has_shm_indels": [true, false], "qr_gap_seqs": ["NNNTAGGTGCAGCTGGTGGAGTCTGGAGGAGGCTTGGTCCAGCCTGGGGGTTCCCTGAGACTCTCCTGTGCAACCTCTGGATTCACCTTTAGTAGCTATT.GATGAGCAGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAATGGTTGGCCAACATAAAGTAAGATGGAAGTGAGAAATACTATCTGGACTCTGTGAAGGGCCGACTTACCATCTCCAGAGACAACGCCAAGAACTCACTGTATCTGCAAATGAGCAGCCTGAGAGCCGAGGTCACGGCTGTGTATTACTGTGCGAGAGAGAATTCCGCTAGTGGACCTGTTATCGGTGACTCCTGGGGCCAGGGATTCCTGGTCTCCGTCTCCTCAG", ""], "gl_gap_seqs": ["NNNGAGGTGCAGCTGGTGGAGTCTGGGGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGACTCTCCTGTGCAGCCTCTGGATTCACCTTTAGTAGCTATTGGATGAGCTGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAGTGGGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGGACTCTGTGAAGGGCCGATTCACCATCTCCAGAGACAACGCCAAGAACTCACTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGAGGGTCCCGCCAGTGCACCTGATACCGGTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", ""], "indel_reversed_seqs": ["NNNTAGGTGCAGCTGGTGGAGTCTGGAGGAGGCTTGGTCCAGCCTGGGGGTTCCCTGAGACTCTCCTGTGCAACCTCTGGATTCACCTTTAGTAGCTATTGGATGAGCAGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAATGGTTGGCCAACATAAAGTAAGATGGAAGTGAGAAATACTATCTGGACTCTGTGAAGGGCCGACTTACCATCTCCAGAGACAACGCCAAGAACTCACTGTATCTGCAAATGAGCAGCCTGAGAGCCGAGGTCACGGCTGTGTATTACTGTGCGAGAGAGAATTCCGCTAGTGGACCTGTTATCGGTGACTCCTGGGGCCAGGGATTCCTGGTCTCCGTCTCCTCAG", ""], "unique_ids": ["21cea6e4d0-igh", "57537e5f22-igh"], "invalid": false, "v_gene": "IGHV3-7*01", "d_gene": "IGHD3-16*03", "j_gene": "IGHJ4*02", "cdr3_length": 48, "mut_freqs": [0.06593406593406594, 0.06318681318681318], "n_mutations": [24, 23], "input_seqs": ["NNNTAGGTGCAGCTGGTGGAGTCTGGAGGAGGCTTGGTCCAGCCTGGGGGTTCCCTGAGACTCTCCTGTGCAACCTCTGGATTCACCTTTAGTAGCTATTGATGAGCAGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAATGGTTGGCCAACATAAAGTAAGATGGAAGTGAGAAATACTATCTGGACTCTGTGAAGGGCCGACTTACCATCTCCAGAGACAACGCCAAGAACTCACTGTATCTGCAAATGAGCAGCCTGAGAGCCGAGGTCACGGCTGTGTATTACTGTGCGAGAGAGAATTCCGCTAGTGGACCTGTTATCGGTGACTCCTGGGGCCAGGGATTCCTGGTCTCCGTCTCCTCAG", "NNNTAGGTGCAGCTTGTGGAGTCTGGAGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGACTCTCATGTGCAGCCTCTCGATTCACCTTTAGTAGCTATTGGATGAGCTGGGTCCGCCAGGGTCCAGGGAAGGGGCTGGAGTGGGTGGCCGAGATAAAGCAAGATGGTAGTCAGAAATACTATCTGGACTCACTGAAGGGCCGATTCACCAACTCCAGAGACAACGCCAAGACCTCACTGTATCTGCAAATGAGCAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGGGGGTCCCGCCATTGCAACTGACACCGGTGACTACTGGGGCCAGGCAATCCTGGGCACCGTCTCCTCAG"], "naive_seq": "NNNGAGGTGCAGCTGGTGGAGTCTGGGGGAGGCTTGGTCCAGCCTGGGGGGTCCCTGAGACTCTCCTGTGCAGCCTCTGGATTCACCTTTAGTAGCTATTGGATGAGCTGGGTCCGCCAGGCTCCAGGGAAGGGGCTGGAGTGGGTGGCCAACATAAAGCAAGATGGAAGTGAGAAATACTATGTGGACTCTGTGAAGGGCCGATTCACCATCTCCAGAGACAACGCCAAGAACTCACTGTATCTGCAAATGAACAGCCTGAGAGCCGAGGACACGGCTGTGTATTACTGTGCGAGAGAGGGTCCCGCCAGTGCACCTGATACCGGTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[], []], "leader_seqs": ["", ""], "c_gene_seqs": ["", ""], "v_per_gene_support": {"IGHV3-7*01": 1.0}, "d_per_gene_support": {"IGHD3-16*03": 0.7677680346276209, "IGHD1-1*01": 0.23028015877168076, "IGHD6-6*01": 0.0012800212115014128, "IGHD1-26*01": 0.0006717853892368645}, "j_per_gene_support": {"IGHJ4*02": 0.9999992505751117, "IGHJ5*02": 7.494248813636061e-07}, "v_3p_del": 0, "d_5p_del": 32, "d_3p_del": 0, "j_5p_del": 7, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "GGGTCCCGCCAGTGCACCTG", "dj_insertion": "GG", "fv_insertion": "NNN", "jf_insertion": "", "mutated_invariants": [false, false], "in_frames": [false, true], "stops": [true, true], "paired-uids": [["21cea6e4d0-igl"], ["57537e5f22-igl"]], "loci": ["igh", "igh"], "codon_positions": {"v": 288, "j": 333}}, {"has_shm_indels": [true], "qr_gap_seqs": ["CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCAGTGTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACCCCCAACTGGGGACGTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG"], "gl_gap_seqs": ["CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATC....TCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACCCCCAACTGGGGACGTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG"], "indel_reversed_seqs": ["CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACCCCCAACTGGGGACGTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG"], "unique_ids": ["cfe3b29587-igh"], "invalid": false, "v_gene": "IGHV2-70*01", "d_gene": "IGHD7-27*01", "j_gene": "IGHJ4*02", "cdr3_length": 39, "mut_freqs": [0.0], "n_mutations": [0], "input_seqs": ["CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCAGTGTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACCCCCAACTGGGGACGTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG"], "naive_seq": "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACCCCCAACTGGGGACGTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV2-70*01": 1.0}, "d_per_gene_support": {"IGHD7-27*01": 0.9993476455881649, "IGHD1-1*01": 0.0006523544118351107}, "j_per_gene_support": {"IGHJ4*02": 0.9999984857866788, "IGHJ5*02": 1.514213320570988e-06}, "v_3p_del": 0, "d_5p_del": 2, "d_3p_del": 0, "j_5p_del": 7, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "CCCC", "dj_insertion": "CGT", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [false], "stops": [true], "paired-uids": [["09f5010bd3-igl"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 324}}, {"has_shm_indels": [false], "qr_gap_seqs": [""], "gl_gap_seqs": [""], "indel_reversed_seqs": [""], "unique_ids": ["bc11af4843-igh"], "invalid": false, "v_gene": "IGHV2-70*01", "d_gene": "IGHD2-2*01", "j_gene": "IGHJ4*02", "cdr3_length": 39, "mut_freqs": [0.05865921787709497], "n_mutations": [21], "input_seqs": ["CAGGTCAGCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTGTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCAAGGGAAGGCCCTGGAGTGGCTTGCCCTCATTGATTGGGATGATCATAAATACTACAGCAGGACTGTGAAGACCAGGCTCACCATCTTCCAGTACACCTCCAGAAAACAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACTATGCAGAGTCAGCTTTGATTGCTGGGGCCAGGGAAGCCTGGTCACCGTGTCCCCAG"], "naive_seq": "CAGGTCACCTTGAGGGAGTCTGGTCCTGCGCTGGTGAAACCCACACAGACCCTCACACTGACCTGCACCTTCTCTGGGTTCTCACTCAGCACTAGTGGAATGTGTGTGAGCTGGATCCGTCAGCCCCCAGGGAAGGCCCTGGAGTGGCTTGCACTCATTGATTGGGATGATGATAAATACTACAGCACATCTCTGAAGACCAGGCTCACCATCTCCAAGGACACCTCCAAAAACCAGGTGGTCCTTACAATGACCAACATGGACCCTGTGGACACAGCCACGTATTACTGTGCACGGATACTATGCCGAGTCAACTTTGACTACTGGGGCCAGGGAACCCTGGTCACCGTCTCCTCAG", "duplicates": [[]], "leader_seqs": [""], "c_gene_seqs": [""], "v_per_gene_support": {"IGHV2-70*01": 1.0}, "d_per_gene_support": {"IGHD2-2*01": 0.5527021321579755, "IGHD2-8*01": 0.3428150937549728, "IGHD2-8*02": 0.10448277408704772}, "j_per_gene_support": {"IGHJ4*02": 0.9999953481550304, "IGHJ5*02": 4.65184495817866e-06}, "v_3p_del": 0, "d_5p_del": 25, "d_3p_del": 0, "j_5p_del": 3, "v_5p_del": 0, "j_3p_del": 0, "vd_insertion": "", "dj_insertion": "GAGTCA", "fv_insertion": "", "jf_insertion": "", "mutated_invariants": [false], "in_frames": [true], "stops": [false], "paired-uids": [["eee6809ad6-igl"]], "loci": ["igh"], "codon_positions": {"v": 288, "j": 324}}]}