benchling-v3-sdk-python 5.0.0__py3-none-any.whl

benchling_v3_sdk/dna_sequence/raw_client.py

@@ -0,0 +1,3923 @@
+# This file was auto-generated by Fern from our API Definition.
+
+import typing
+from json.decoder import JSONDecodeError
+
+from ..core.api_error import ApiError
+from ..core.client_wrapper import AsyncClientWrapper, SyncClientWrapper
+from ..core.http_response import AsyncHttpResponse, HttpResponse
+from ..core.jsonable_encoder import encode_path_param
+from ..core.pagination import AsyncPager, SyncPager
+from ..core.parse_error import ParsingError
+from ..core.pydantic_utilities import parse_obj_as
+from ..core.request_options import RequestOptions
+from ..core.serialization import convert_and_respect_annotation_metadata
+from ..errors.bad_request_error import BadRequestError
+from ..errors.forbidden_error import ForbiddenError
+from ..errors.internal_server_error import InternalServerError
+from ..errors.not_found_error import NotFoundError
+from ..errors.too_many_requests_error import TooManyRequestsError
+from ..types.async_task_link import AsyncTaskLink
+from ..types.create_dna_sequence_input import CreateDnaSequenceInput
+from ..types.create_dna_sequence_input_naming_strategy import CreateDnaSequenceInputNamingStrategy
+from ..types.dna_part import DnaPart
+from ..types.dna_part_paginated_list import DnaPartPaginatedList
+from ..types.dna_sequence import DnaSequence
+from ..types.dna_sequence_paginated_list import DnaSequencePaginatedList
+from ..types.field_value_input import FieldValueInput
+from ..types.general_error import GeneralError
+from ..types.internal_server_error_body import InternalServerErrorBody
+from ..types.nucleotide_alignment_unpaginated_list import NucleotideAlignmentUnpaginatedList
+from ..types.nucleotide_annotation import NucleotideAnnotation
+from ..types.nucleotide_annotation_input import NucleotideAnnotationInput
+from ..types.nucleotide_annotation_paginated_list import NucleotideAnnotationPaginatedList
+from ..types.nucleotide_part_input import NucleotidePartInput
+from ..types.primer import Primer
+from ..types.primer_input import PrimerInput
+from ..types.primer_paginated_list import PrimerPaginatedList
+from ..types.principal_unpaginated_list import PrincipalUnpaginatedList
+from ..types.translation import Translation
+from ..types.translation_input import TranslationInput
+from ..types.translation_paginated_list import TranslationPaginatedList
+from ..types.update_dna_sequence_input_with_path_params import UpdateDnaSequenceInputWithPathParams
+from .types.batch_create_dna_sequence_response import BatchCreateDnaSequenceResponse
+from .types.batch_update_dna_sequence_response import BatchUpdateDnaSequenceResponse
+from .types.list_dna_sequence_request_sort import ListDnaSequenceRequestSort
+from .types.update_dna_sequence_input_naming_strategy import UpdateDnaSequenceInputNamingStrategy
+from pydantic import ValidationError
+
+# this is used as the default value for optional parameters
+OMIT = typing.cast(typing.Any, ...)
+
+
+class RawDnaSequenceClient:
+    def __init__(self, *, client_wrapper: SyncClientWrapper):
+        self._client_wrapper = client_wrapper
+
+    def create(
+        self,
+        *,
+        bases: str,
+        folder_id: str,
+        name: str,
+        aliases: typing.Optional[typing.Sequence[str]] = OMIT,
+        annotations: typing.Optional[typing.Sequence[NucleotideAnnotationInput]] = OMIT,
+        author_ids: typing.Optional[typing.Sequence[str]] = OMIT,
+        custom_fields: typing.Optional[typing.Dict[str, FieldValueInput]] = OMIT,
+        entity_registry_id: typing.Optional[str] = OMIT,
+        is_circular: typing.Optional[bool] = OMIT,
+        naming_strategy: typing.Optional[CreateDnaSequenceInputNamingStrategy] = OMIT,
+        parts: typing.Optional[typing.Sequence[NucleotidePartInput]] = OMIT,
+        primers: typing.Optional[typing.Sequence[PrimerInput]] = OMIT,
+        registry_id: typing.Optional[str] = OMIT,
+        schema_fields: typing.Optional[typing.Dict[str, FieldValueInput]] = OMIT,
+        schema_id: typing.Optional[str] = OMIT,
+        translations: typing.Optional[typing.Sequence[TranslationInput]] = OMIT,
+        request_options: typing.Optional[RequestOptions] = None,
+    ) -> HttpResponse[DnaSequence]:
+        """
+        Create DnaSequence.
+
+        Parameters
+        ----------
+        bases : str
+            Bases of the forward strand of the DNA sequence.
+
+        folder_id : str
+
+        name : str
+            Name of the item.
+
+        aliases : typing.Optional[typing.Sequence[str]]
+            Array of aliases
+
+        annotations : typing.Optional[typing.Sequence[NucleotideAnnotationInput]]
+            Annotations on the DNA sequence, not including translations or primers. Annotations on parts are
+            not included.
+
+        author_ids : typing.Optional[typing.Sequence[str]]
+
+        custom_fields : typing.Optional[typing.Dict[str, FieldValueInput]]
+            Custom fields set on the DNA sequence.
+
+        entity_registry_id : typing.Optional[str]
+            Registry ID to assign to the entity. If one is specified, the labeling_strategy must be unspecified.
+
+        is_circular : typing.Optional[bool]
+            Whether the sequence forms a closed loop, with the last base connecting back to the first. Defaults to false if not specified.
+
+        naming_strategy : typing.Optional[CreateDnaSequenceInputNamingStrategy]
+            Strategy to use for labeling the item in the registry. If one is specified, the entity_registry_id must be unspecified.
+
+        parts : typing.Optional[typing.Sequence[NucleotidePartInput]]
+            Part features linking regions of this sequence to other nucleotide sequences.
+
+        primers : typing.Optional[typing.Sequence[PrimerInput]]
+            Primer bind features on the DNA sequence. Primers on parts are not included.
+
+        registry_id : typing.Optional[str]
+            A not null value means the entity should be registered. If not null, the value must match the registry of the item's schema.
+
+        schema_fields : typing.Optional[typing.Dict[str, FieldValueInput]]
+
+        schema_id : typing.Optional[str]
+
+        translations : typing.Optional[typing.Sequence[TranslationInput]]
+            Translation annotations present on the DNA sequence. Translations may be one region or split
+            across multiple regions. Translations on parts are not included.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        HttpResponse[DnaSequence]
+            Created
+        """
+        _response = self._client_wrapper.httpx_client.request(
+            "api/v3/dna-sequence",
+            method="POST",
+            json={
+                "aliases": aliases,
+                "annotations": convert_and_respect_annotation_metadata(
+                    object_=annotations, annotation=typing.Sequence[NucleotideAnnotationInput], direction="write"
+                ),
+                "authorIds": author_ids,
+                "bases": bases,
+                "customFields": convert_and_respect_annotation_metadata(
+                    object_=custom_fields, annotation=typing.Dict[str, FieldValueInput], direction="write"
+                ),
+                "entityRegistryId": entity_registry_id,
+                "folderId": folder_id,
+                "isCircular": is_circular,
+                "name": name,
+                "namingStrategy": naming_strategy,
+                "parts": convert_and_respect_annotation_metadata(
+                    object_=parts, annotation=typing.Sequence[NucleotidePartInput], direction="write"
+                ),
+                "primers": convert_and_respect_annotation_metadata(
+                    object_=primers, annotation=typing.Sequence[PrimerInput], direction="write"
+                ),
+                "registryId": registry_id,
+                "schemaFields": convert_and_respect_annotation_metadata(
+                    object_=schema_fields, annotation=typing.Dict[str, FieldValueInput], direction="write"
+                ),
+                "schemaId": schema_id,
+                "translations": convert_and_respect_annotation_metadata(
+                    object_=translations, annotation=typing.Sequence[TranslationInput], direction="write"
+                ),
+            },
+            request_options=request_options,
+            omit=OMIT,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _data = typing.cast(
+                    DnaSequence,
+                    parse_obj_as(
+                        type_=DnaSequence,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                return HttpResponse(response=_response, data=_data)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    def list(
+        self,
+        *,
+        archive_reason_any_of: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        archived_any_of: typing.Optional[typing.Union[bool, typing.Sequence[bool]]] = None,
+        authors_any_of: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        bases_any_of: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        created_at_gt: typing.Optional[str] = None,
+        created_at_gte: typing.Optional[str] = None,
+        created_at_lt: typing.Optional[str] = None,
+        created_at_lte: typing.Optional[str] = None,
+        creator_any_of: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        entity_registry_ids_any_of: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        fieldset_any_of: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        folder_eq: typing.Optional[str] = None,
+        id_any_of: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        mentioned_in_any_of: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        modified_at_gt: typing.Optional[str] = None,
+        modified_at_gte: typing.Optional[str] = None,
+        modified_at_lt: typing.Optional[str] = None,
+        modified_at_lte: typing.Optional[str] = None,
+        name_any_of: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        name_any_of_case_sensitive: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        next_token: typing.Optional[str] = None,
+        omit: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        page_size: typing.Optional[int] = None,
+        project_eq: typing.Optional[str] = None,
+        registry_eq: typing.Optional[str] = None,
+        returning: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        schema_any_of: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        schema_eq: typing.Optional[str] = None,
+        system_category_any_of: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        sort: typing.Optional[ListDnaSequenceRequestSort] = None,
+        request_options: typing.Optional[RequestOptions] = None,
+    ) -> SyncPager[DnaSequence, DnaSequencePaginatedList]:
+        """
+        List DnaSequence items.
+
+        Parameters
+        ----------
+        archive_reason_any_of : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts items to those with any of the specified archive reasons. Use "NOT_ARCHIVED" to filter for unarchived items. Use "ANY_ARCHIVED" to filter for archived items regardless of reason. Use "ANY_ARCHIVED_OR_NOT_ARCHIVED" to return items for both archived and unarchived. Comma-separated list.
+
+        archived_any_of : typing.Optional[typing.Union[bool, typing.Sequence[bool]]]
+            If true, returns archived items. If false, returns unarchived items. If both true and false, returns archived and unarchived items. Comma-separated list.
+
+        authors_any_of : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts results to those whose author matches any of the specified user or author IDs. Comma-separated list.
+
+        bases_any_of : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts results to those whose sequence exactly matches any of the specified DNA base sequences (case-insensitive, accounting for circular and reverse complement). Comma-separated list.
+
+        created_at_gt : typing.Optional[str]
+            Datetime, in RFC 3339 format. Time zone defaults to UTC. Restricts results to those created after the specified time. e.g. > 2017-04-30.
+
+        created_at_gte : typing.Optional[str]
+            Datetime, in RFC 3339 format. Time zone defaults to UTC. Restricts results to those created at or after the specified time. e.g. >= 2017-04-30.
+
+        created_at_lt : typing.Optional[str]
+            Datetime, in RFC 3339 format. Time zone defaults to UTC. Restricts results to those created before the specified time. e.g. < 2017-04-30.
+
+        created_at_lte : typing.Optional[str]
+            Datetime, in RFC 3339 format. Time zone defaults to UTC. Restricts results to those created at or before the specified time. e.g. <= 2017-04-30.
+
+        creator_any_of : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts results to those created by any of the specified user IDs. Comma-separated list.
+
+        entity_registry_ids_any_of : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts results to those that match any of the specified entity registry IDs. Comma-separated list.
+
+        fieldset_any_of : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts results to those whose schema implements any of the specified fieldset API IDs (custom schema interfaces). Comma-separated list.
+
+        folder_eq : typing.Optional[str]
+            ID of a folder. Restricts results to its direct children.
+
+        id_any_of : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts results to those matching any of the specified IDs. Comma-separated list.
+
+        mentioned_in_any_of : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts results to items mentioned in entries matching any of the specified entry IDs. Comma-separated list.
+
+        modified_at_gt : typing.Optional[str]
+            Datetime, in RFC 3339 format. Time zone defaults to UTC. Restricts results to those modified after the specified time. e.g. > 2017-04-30.
+
+        modified_at_gte : typing.Optional[str]
+            Datetime, in RFC 3339 format. Time zone defaults to UTC. Restricts results to those modified at or after the specified time. e.g. >= 2017-04-30.
+
+        modified_at_lt : typing.Optional[str]
+            Datetime, in RFC 3339 format. Time zone defaults to UTC. Restricts results to those modified before the specified time. e.g. < 2017-04-30.
+
+        modified_at_lte : typing.Optional[str]
+            Datetime, in RFC 3339 format. Time zone defaults to UTC. Restricts results to those modified at or before the specified time. e.g. <= 2017-04-30.
+
+        name_any_of : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts results to those that match any of the specified names. Case insensitive. Warning - this filter can be non-performant due to case insensitivity. Ensure only one name filter is used at a time. Comma-separated list.
+
+        name_any_of_case_sensitive : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts results to those that match any of the specified names. Case sensitive. Ensure only one name filter is used at a time. Comma-separated list.
+
+        next_token : typing.Optional[str]
+            Token for pagination
+
+        omit : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Comma-separated list of top-level fields to omit from each returned item. Cannot overlap with returning.
+
+        page_size : typing.Optional[int]
+            Number of results to return. Defaults to 50, maximum of 100.
+
+        project_eq : typing.Optional[str]
+            ID of a project. Restricts results to those in the project.
+
+        registry_eq : typing.Optional[str]
+            ID of a registry. Restricts results to those registered in this registry. Specifying "null" returns unregistered items.
+
+        returning : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Comma-separated list of top-level fields to include in each returned item. Cannot overlap with omit.
+
+        schema_any_of : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts results to those that match any of the specified schema IDs. Use only one `schema` filter arg at a time. Comma-separated list.
+
+        schema_eq : typing.Optional[str]
+            Single schema ID. Restricts results to those that match the specified schema exactly. Use only one `schema` filter arg at a time.
+
+        system_category_any_of : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts results to those whose schema implements any of the specified system category API IDs (non-exclusive static schema interfaces). Comma-separated list.
+
+        sort : typing.Optional[ListDnaSequenceRequestSort]
+            Method by which to order results. Valid sorts are: createdAt (created time, oldest first) and modifiedAt (modified time, oldest first). Use :asc or :desc to specify ascending or descending order. Default is modifiedAt:desc.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        SyncPager[DnaSequence, DnaSequencePaginatedList]
+            OK
+        """
+        _response = self._client_wrapper.httpx_client.request(
+            "api/v3/dna-sequence/items",
+            method="GET",
+            params={
+                "archiveReason.anyOf": ",".join(map(str, archive_reason_any_of))
+                if isinstance(archive_reason_any_of, (list, tuple, set))
+                else archive_reason_any_of,
+                "archived.anyOf": ",".join(map(str, archived_any_of))
+                if isinstance(archived_any_of, (list, tuple, set))
+                else archived_any_of,
+                "authors.anyOf": ",".join(map(str, authors_any_of))
+                if isinstance(authors_any_of, (list, tuple, set))
+                else authors_any_of,
+                "bases.anyOf": ",".join(map(str, bases_any_of))
+                if isinstance(bases_any_of, (list, tuple, set))
+                else bases_any_of,
+                "createdAt.gt": created_at_gt,
+                "createdAt.gte": created_at_gte,
+                "createdAt.lt": created_at_lt,
+                "createdAt.lte": created_at_lte,
+                "creator.anyOf": ",".join(map(str, creator_any_of))
+                if isinstance(creator_any_of, (list, tuple, set))
+                else creator_any_of,
+                "entityRegistryIds.anyOf": ",".join(map(str, entity_registry_ids_any_of))
+                if isinstance(entity_registry_ids_any_of, (list, tuple, set))
+                else entity_registry_ids_any_of,
+                "fieldset.anyOf": ",".join(map(str, fieldset_any_of))
+                if isinstance(fieldset_any_of, (list, tuple, set))
+                else fieldset_any_of,
+                "folder.eq": folder_eq,
+                "id.anyOf": ",".join(map(str, id_any_of)) if isinstance(id_any_of, (list, tuple, set)) else id_any_of,
+                "mentionedIn.anyOf": ",".join(map(str, mentioned_in_any_of))
+                if isinstance(mentioned_in_any_of, (list, tuple, set))
+                else mentioned_in_any_of,
+                "modifiedAt.gt": modified_at_gt,
+                "modifiedAt.gte": modified_at_gte,
+                "modifiedAt.lt": modified_at_lt,
+                "modifiedAt.lte": modified_at_lte,
+                "name.anyOf": ",".join(map(str, name_any_of))
+                if isinstance(name_any_of, (list, tuple, set))
+                else name_any_of,
+                "name.anyOf.caseSensitive": ",".join(map(str, name_any_of_case_sensitive))
+                if isinstance(name_any_of_case_sensitive, (list, tuple, set))
+                else name_any_of_case_sensitive,
+                "nextToken": next_token,
+                "omit": ",".join(map(str, omit)) if isinstance(omit, (list, tuple, set)) else omit,
+                "pageSize": page_size,
+                "project.eq": project_eq,
+                "registry.eq": registry_eq,
+                "returning": ",".join(map(str, returning)) if isinstance(returning, (list, tuple, set)) else returning,
+                "schema.anyOf": ",".join(map(str, schema_any_of))
+                if isinstance(schema_any_of, (list, tuple, set))
+                else schema_any_of,
+                "schema.eq": schema_eq,
+                "systemCategory.anyOf": ",".join(map(str, system_category_any_of))
+                if isinstance(system_category_any_of, (list, tuple, set))
+                else system_category_any_of,
+                "sort": sort,
+            },
+            request_options=request_options,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _parsed_response = typing.cast(
+                    DnaSequencePaginatedList,
+                    parse_obj_as(
+                        type_=DnaSequencePaginatedList,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                _items = _parsed_response.items
+                _parsed_next = _parsed_response.next_token
+                _has_next = _parsed_next is not None and _parsed_next != ""
+                _get_next = lambda: self.list(
+                    archive_reason_any_of=archive_reason_any_of,
+                    archived_any_of=archived_any_of,
+                    authors_any_of=authors_any_of,
+                    bases_any_of=bases_any_of,
+                    created_at_gt=created_at_gt,
+                    created_at_gte=created_at_gte,
+                    created_at_lt=created_at_lt,
+                    created_at_lte=created_at_lte,
+                    creator_any_of=creator_any_of,
+                    entity_registry_ids_any_of=entity_registry_ids_any_of,
+                    fieldset_any_of=fieldset_any_of,
+                    folder_eq=folder_eq,
+                    id_any_of=id_any_of,
+                    mentioned_in_any_of=mentioned_in_any_of,
+                    modified_at_gt=modified_at_gt,
+                    modified_at_gte=modified_at_gte,
+                    modified_at_lt=modified_at_lt,
+                    modified_at_lte=modified_at_lte,
+                    name_any_of=name_any_of,
+                    name_any_of_case_sensitive=name_any_of_case_sensitive,
+                    next_token=_parsed_next,
+                    omit=omit,
+                    page_size=page_size,
+                    project_eq=project_eq,
+                    registry_eq=registry_eq,
+                    returning=returning,
+                    schema_any_of=schema_any_of,
+                    schema_eq=schema_eq,
+                    system_category_any_of=system_category_any_of,
+                    sort=sort,
+                    request_options=request_options,
+                )
+                return SyncPager(has_next=_has_next, items=_items, get_next=_get_next, response=_parsed_response)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    def get(
+        self,
+        dna_sequence_id: str,
+        *,
+        returning: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        omit: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        request_options: typing.Optional[RequestOptions] = None,
+    ) -> HttpResponse[DnaSequence]:
+        """
+        Get a single DnaSequence by ID.
+
+        Parameters
+        ----------
+        dna_sequence_id : str
+            ID of the DnaSequence.
+
+        returning : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Comma-separated list of top-level fields to include in each returned item. Cannot overlap with omit.
+
+        omit : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Comma-separated list of top-level fields to omit from each returned item. Cannot overlap with returning.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        HttpResponse[DnaSequence]
+            OK
+        """
+        _response = self._client_wrapper.httpx_client.request(
+            f"api/v3/dna-sequence/{encode_path_param(dna_sequence_id)}",
+            method="GET",
+            params={
+                "returning": ",".join(map(str, returning)) if isinstance(returning, (list, tuple, set)) else returning,
+                "omit": ",".join(map(str, omit)) if isinstance(omit, (list, tuple, set)) else omit,
+            },
+            request_options=request_options,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _data = typing.cast(
+                    DnaSequence,
+                    parse_obj_as(
+                        type_=DnaSequence,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                return HttpResponse(response=_response, data=_data)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    def update(
+        self,
+        dna_sequence_id: str,
+        *,
+        aliases: typing.Optional[typing.Sequence[str]] = OMIT,
+        annotations: typing.Optional[typing.Sequence[NucleotideAnnotationInput]] = OMIT,
+        archive_reason: typing.Optional[str] = OMIT,
+        archived: typing.Optional[bool] = OMIT,
+        author_ids: typing.Optional[typing.Sequence[str]] = OMIT,
+        bases: typing.Optional[str] = OMIT,
+        custom_fields: typing.Optional[typing.Dict[str, FieldValueInput]] = OMIT,
+        entity_registry_id: typing.Optional[str] = OMIT,
+        folder_id: typing.Optional[str] = OMIT,
+        is_circular: typing.Optional[bool] = OMIT,
+        name: typing.Optional[str] = OMIT,
+        naming_strategy: typing.Optional[UpdateDnaSequenceInputNamingStrategy] = OMIT,
+        parts: typing.Optional[typing.Sequence[NucleotidePartInput]] = OMIT,
+        primers: typing.Optional[typing.Sequence[PrimerInput]] = OMIT,
+        registry_id: typing.Optional[str] = OMIT,
+        schema_fields: typing.Optional[typing.Dict[str, FieldValueInput]] = OMIT,
+        schema_id: typing.Optional[str] = OMIT,
+        translations: typing.Optional[typing.Sequence[TranslationInput]] = OMIT,
+        request_options: typing.Optional[RequestOptions] = None,
+    ) -> HttpResponse[DnaSequence]:
+        """
+        Update a DNA sequence. The `id` path parameter identifies the DNA sequence to update.
+
+        ## Updating bases
+
+        When replacing `bases`, include every sequence feature collection that already exists on the sequence: `annotations`, `translations`, `primers`, and `parts`. Provide the updated values or an empty array (`[]`) to clear a collection. Omitting a key that has existing data returns `400`.
+
+        Parameters
+        ----------
+        dna_sequence_id : str
+            ID of the DnaSequence.
+
+        aliases : typing.Optional[typing.Sequence[str]]
+            Array of aliases
+
+        annotations : typing.Optional[typing.Sequence[NucleotideAnnotationInput]]
+            Annotations on the DNA sequence, not including translations or primers. Annotations on parts are
+            not included.
+
+        archive_reason : typing.Optional[str]
+
+        archived : typing.Optional[bool]
+
+        author_ids : typing.Optional[typing.Sequence[str]]
+
+        bases : typing.Optional[str]
+            Bases of the forward strand of the DNA sequence.
+
+        custom_fields : typing.Optional[typing.Dict[str, FieldValueInput]]
+            Custom fields set on the DNA sequence.
+
+        entity_registry_id : typing.Optional[str]
+            Registry ID to assign to the entity. When registering, specifying this value sets the registry ID of the entity. When already registered, specifying this value updates the entity's registry ID. If set, naming_strategy must be unspecified.
+
+        folder_id : typing.Optional[str]
+
+        is_circular : typing.Optional[bool]
+            Whether the sequence forms a closed loop, with the last base connecting back to the first. Defaults to false if not specified.
+
+        name : typing.Optional[str]
+            Name of the item.
+
+        naming_strategy : typing.Optional[UpdateDnaSequenceInputNamingStrategy]
+            Strategy to use for labeling the item in the registry if registering. If one is specified, the entity_registry_id must be unspecified.
+
+        parts : typing.Optional[typing.Sequence[NucleotidePartInput]]
+            Part features linking regions of this sequence to other nucleotide sequences.
+
+        primers : typing.Optional[typing.Sequence[PrimerInput]]
+            Primer bind features on the DNA sequence. Primers on parts are not included.
+
+        registry_id : typing.Optional[str]
+            A not null value means the entity should be registered. A null value means it should be unregistered. If not null, the value must match the registry of the item's schema.
+
+        schema_fields : typing.Optional[typing.Dict[str, FieldValueInput]]
+
+        schema_id : typing.Optional[str]
+
+        translations : typing.Optional[typing.Sequence[TranslationInput]]
+            Translation annotations present on the DNA sequence. Translations may be one region or split
+            across multiple regions. Translations on parts are not included.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        HttpResponse[DnaSequence]
+            OK
+        """
+        _response = self._client_wrapper.httpx_client.request(
+            f"api/v3/dna-sequence/{encode_path_param(dna_sequence_id)}",
+            method="PATCH",
+            json={
+                "aliases": aliases,
+                "annotations": convert_and_respect_annotation_metadata(
+                    object_=annotations, annotation=typing.Sequence[NucleotideAnnotationInput], direction="write"
+                ),
+                "archiveReason": archive_reason,
+                "archived": archived,
+                "authorIds": author_ids,
+                "bases": bases,
+                "customFields": convert_and_respect_annotation_metadata(
+                    object_=custom_fields, annotation=typing.Dict[str, FieldValueInput], direction="write"
+                ),
+                "entityRegistryId": entity_registry_id,
+                "folderId": folder_id,
+                "isCircular": is_circular,
+                "name": name,
+                "namingStrategy": naming_strategy,
+                "parts": convert_and_respect_annotation_metadata(
+                    object_=parts, annotation=typing.Sequence[NucleotidePartInput], direction="write"
+                ),
+                "primers": convert_and_respect_annotation_metadata(
+                    object_=primers, annotation=typing.Sequence[PrimerInput], direction="write"
+                ),
+                "registryId": registry_id,
+                "schemaFields": convert_and_respect_annotation_metadata(
+                    object_=schema_fields, annotation=typing.Dict[str, FieldValueInput], direction="write"
+                ),
+                "schemaId": schema_id,
+                "translations": convert_and_respect_annotation_metadata(
+                    object_=translations, annotation=typing.Sequence[TranslationInput], direction="write"
+                ),
+            },
+            headers={
+                "content-type": "application/json",
+            },
+            request_options=request_options,
+            omit=OMIT,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _data = typing.cast(
+                    DnaSequence,
+                    parse_obj_as(
+                        type_=DnaSequence,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                return HttpResponse(response=_response, data=_data)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    def list_annotations(
+        self,
+        dna_sequence_id: str,
+        *,
+        next_token: typing.Optional[str] = None,
+        page_size: typing.Optional[int] = None,
+        request_options: typing.Optional[RequestOptions] = None,
+    ) -> SyncPager[NucleotideAnnotation, NucleotideAnnotationPaginatedList]:
+        """
+        List NucleotideAnnotation items.
+
+        Parameters
+        ----------
+        dna_sequence_id : str
+            ID of the DnaSequence.
+
+        next_token : typing.Optional[str]
+            Token for pagination
+
+        page_size : typing.Optional[int]
+            Number of results to return. Defaults to 50, maximum of 100.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        SyncPager[NucleotideAnnotation, NucleotideAnnotationPaginatedList]
+            OK
+        """
+        _response = self._client_wrapper.httpx_client.request(
+            f"api/v3/dna-sequence/{encode_path_param(dna_sequence_id)}/annotations/items",
+            method="GET",
+            params={
+                "nextToken": next_token,
+                "pageSize": page_size,
+            },
+            request_options=request_options,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _parsed_response = typing.cast(
+                    NucleotideAnnotationPaginatedList,
+                    parse_obj_as(
+                        type_=NucleotideAnnotationPaginatedList,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                _items = _parsed_response.items
+                _parsed_next = _parsed_response.next_token
+                _has_next = _parsed_next is not None and _parsed_next != ""
+                _get_next = lambda: self.list_annotations(
+                    dna_sequence_id,
+                    next_token=_parsed_next,
+                    page_size=page_size,
+                    request_options=request_options,
+                )
+                return SyncPager(has_next=_has_next, items=_items, get_next=_get_next, response=_parsed_response)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    def list_authors(
+        self, dna_sequence_id: str, *, request_options: typing.Optional[RequestOptions] = None
+    ) -> HttpResponse[PrincipalUnpaginatedList]:
+        """
+        List Principal items.
+
+        Parameters
+        ----------
+        dna_sequence_id : str
+            ID of the DnaSequence.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        HttpResponse[PrincipalUnpaginatedList]
+            OK
+        """
+        _response = self._client_wrapper.httpx_client.request(
+            f"api/v3/dna-sequence/{encode_path_param(dna_sequence_id)}/authors/items",
+            method="GET",
+            request_options=request_options,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _data = typing.cast(
+                    PrincipalUnpaginatedList,
+                    parse_obj_as(
+                        type_=PrincipalUnpaginatedList,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                return HttpResponse(response=_response, data=_data)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    def list_nucleotide_alignments(
+        self, dna_sequence_id: str, *, request_options: typing.Optional[RequestOptions] = None
+    ) -> HttpResponse[NucleotideAlignmentUnpaginatedList]:
+        """
+        List NucleotideAlignment items.
+
+        Parameters
+        ----------
+        dna_sequence_id : str
+            ID of the DnaSequence.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        HttpResponse[NucleotideAlignmentUnpaginatedList]
+            OK
+        """
+        _response = self._client_wrapper.httpx_client.request(
+            f"api/v3/dna-sequence/{encode_path_param(dna_sequence_id)}/nucleotide-alignments/items",
+            method="GET",
+            request_options=request_options,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _data = typing.cast(
+                    NucleotideAlignmentUnpaginatedList,
+                    parse_obj_as(
+                        type_=NucleotideAlignmentUnpaginatedList,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                return HttpResponse(response=_response, data=_data)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    def list_parts(
+        self,
+        dna_sequence_id: str,
+        *,
+        next_token: typing.Optional[str] = None,
+        page_size: typing.Optional[int] = None,
+        request_options: typing.Optional[RequestOptions] = None,
+    ) -> SyncPager[DnaPart, DnaPartPaginatedList]:
+        """
+        List DnaPart items.
+
+        Parameters
+        ----------
+        dna_sequence_id : str
+            ID of the DnaSequence.
+
+        next_token : typing.Optional[str]
+            Token for pagination
+
+        page_size : typing.Optional[int]
+            Number of results to return. Defaults to 50, maximum of 100.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        SyncPager[DnaPart, DnaPartPaginatedList]
+            OK
+        """
+        _response = self._client_wrapper.httpx_client.request(
+            f"api/v3/dna-sequence/{encode_path_param(dna_sequence_id)}/parts/items",
+            method="GET",
+            params={
+                "nextToken": next_token,
+                "pageSize": page_size,
+            },
+            request_options=request_options,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _parsed_response = typing.cast(
+                    DnaPartPaginatedList,
+                    parse_obj_as(
+                        type_=DnaPartPaginatedList,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                _items = _parsed_response.items
+                _parsed_next = _parsed_response.next_token
+                _has_next = _parsed_next is not None and _parsed_next != ""
+                _get_next = lambda: self.list_parts(
+                    dna_sequence_id,
+                    next_token=_parsed_next,
+                    page_size=page_size,
+                    request_options=request_options,
+                )
+                return SyncPager(has_next=_has_next, items=_items, get_next=_get_next, response=_parsed_response)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    def list_primers(
+        self,
+        dna_sequence_id: str,
+        *,
+        next_token: typing.Optional[str] = None,
+        page_size: typing.Optional[int] = None,
+        request_options: typing.Optional[RequestOptions] = None,
+    ) -> SyncPager[Primer, PrimerPaginatedList]:
+        """
+        List Primer items.
+
+        Parameters
+        ----------
+        dna_sequence_id : str
+            ID of the DnaSequence.
+
+        next_token : typing.Optional[str]
+            Token for pagination
+
+        page_size : typing.Optional[int]
+            Number of results to return. Defaults to 50, maximum of 100.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        SyncPager[Primer, PrimerPaginatedList]
+            OK
+        """
+        _response = self._client_wrapper.httpx_client.request(
+            f"api/v3/dna-sequence/{encode_path_param(dna_sequence_id)}/primers/items",
+            method="GET",
+            params={
+                "nextToken": next_token,
+                "pageSize": page_size,
+            },
+            request_options=request_options,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _parsed_response = typing.cast(
+                    PrimerPaginatedList,
+                    parse_obj_as(
+                        type_=PrimerPaginatedList,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                _items = _parsed_response.items
+                _parsed_next = _parsed_response.next_token
+                _has_next = _parsed_next is not None and _parsed_next != ""
+                _get_next = lambda: self.list_primers(
+                    dna_sequence_id,
+                    next_token=_parsed_next,
+                    page_size=page_size,
+                    request_options=request_options,
+                )
+                return SyncPager(has_next=_has_next, items=_items, get_next=_get_next, response=_parsed_response)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    def list_translations(
+        self,
+        dna_sequence_id: str,
+        *,
+        next_token: typing.Optional[str] = None,
+        page_size: typing.Optional[int] = None,
+        request_options: typing.Optional[RequestOptions] = None,
+    ) -> SyncPager[Translation, TranslationPaginatedList]:
+        """
+        List Translation items.
+
+        Parameters
+        ----------
+        dna_sequence_id : str
+            ID of the DnaSequence.
+
+        next_token : typing.Optional[str]
+            Token for pagination
+
+        page_size : typing.Optional[int]
+            Number of results to return. Defaults to 50, maximum of 100.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        SyncPager[Translation, TranslationPaginatedList]
+            OK
+        """
+        _response = self._client_wrapper.httpx_client.request(
+            f"api/v3/dna-sequence/{encode_path_param(dna_sequence_id)}/translations/items",
+            method="GET",
+            params={
+                "nextToken": next_token,
+                "pageSize": page_size,
+            },
+            request_options=request_options,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _parsed_response = typing.cast(
+                    TranslationPaginatedList,
+                    parse_obj_as(
+                        type_=TranslationPaginatedList,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                _items = _parsed_response.items
+                _parsed_next = _parsed_response.next_token
+                _has_next = _parsed_next is not None and _parsed_next != ""
+                _get_next = lambda: self.list_translations(
+                    dna_sequence_id,
+                    next_token=_parsed_next,
+                    page_size=page_size,
+                    request_options=request_options,
+                )
+                return SyncPager(has_next=_has_next, items=_items, get_next=_get_next, response=_parsed_response)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    def batch_create(
+        self, *, items: typing.Sequence[CreateDnaSequenceInput], request_options: typing.Optional[RequestOptions] = None
+    ) -> HttpResponse[BatchCreateDnaSequenceResponse]:
+        """
+        Batch create DnaSequence synchronously in one transaction. Maximum 25 items per request.
+
+        Parameters
+        ----------
+        items : typing.Sequence[CreateDnaSequenceInput]
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        HttpResponse[BatchCreateDnaSequenceResponse]
+            Created
+        """
+        _response = self._client_wrapper.httpx_client.request(
+            "api/v3/dna-sequence:batch-create",
+            method="POST",
+            json={
+                "items": convert_and_respect_annotation_metadata(
+                    object_=items, annotation=typing.Sequence[CreateDnaSequenceInput], direction="write"
+                ),
+            },
+            headers={
+                "content-type": "application/json",
+            },
+            request_options=request_options,
+            omit=OMIT,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _data = typing.cast(
+                    BatchCreateDnaSequenceResponse,
+                    parse_obj_as(
+                        type_=BatchCreateDnaSequenceResponse,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                return HttpResponse(response=_response, data=_data)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    def batch_update(
+        self,
+        *,
+        items: typing.Sequence[UpdateDnaSequenceInputWithPathParams],
+        request_options: typing.Optional[RequestOptions] = None,
+    ) -> HttpResponse[BatchUpdateDnaSequenceResponse]:
+        """
+        Batch update DnaSequence synchronously in one transaction. Maximum 25 items per request.
+
+        Parameters
+        ----------
+        items : typing.Sequence[UpdateDnaSequenceInputWithPathParams]
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        HttpResponse[BatchUpdateDnaSequenceResponse]
+            OK
+        """
+        _response = self._client_wrapper.httpx_client.request(
+            "api/v3/dna-sequence:batch-update",
+            method="PATCH",
+            json={
+                "items": convert_and_respect_annotation_metadata(
+                    object_=items, annotation=typing.Sequence[UpdateDnaSequenceInputWithPathParams], direction="write"
+                ),
+            },
+            headers={
+                "content-type": "application/json",
+            },
+            request_options=request_options,
+            omit=OMIT,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _data = typing.cast(
+                    BatchUpdateDnaSequenceResponse,
+                    parse_obj_as(
+                        type_=BatchUpdateDnaSequenceResponse,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                return HttpResponse(response=_response, data=_data)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    def bulk_create(
+        self, *, file_id: str, request_options: typing.Optional[RequestOptions] = None
+    ) -> HttpResponse[AsyncTaskLink]:
+        """
+        Bulk create DnaSequence.
+
+        Parameters
+        ----------
+        file_id : str
+            The API ID of the scratch file (`scrfile_XXXXXXXX`) containing the items to import. The referenced file must be a scratch file whose upload has completed successfully.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        HttpResponse[AsyncTaskLink]
+            Task started
+        """
+        _response = self._client_wrapper.httpx_client.request(
+            "api/v3/dna-sequence:bulk-create",
+            method="POST",
+            json={
+                "fileId": file_id,
+            },
+            request_options=request_options,
+            omit=OMIT,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _data = typing.cast(
+                    AsyncTaskLink,
+                    parse_obj_as(
+                        type_=AsyncTaskLink,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                return HttpResponse(response=_response, data=_data)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    def bulk_update(
+        self, *, file_id: str, request_options: typing.Optional[RequestOptions] = None
+    ) -> HttpResponse[AsyncTaskLink]:
+        """
+        Bulk update DnaSequence.
+
+        Parameters
+        ----------
+        file_id : str
+            The API ID of the scratch file (`scrfile_XXXXXXXX`) containing the items to import. The referenced file must be a scratch file whose upload has completed successfully.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        HttpResponse[AsyncTaskLink]
+            Task started
+        """
+        _response = self._client_wrapper.httpx_client.request(
+            "api/v3/dna-sequence:bulk-update",
+            method="PATCH",
+            json={
+                "fileId": file_id,
+            },
+            request_options=request_options,
+            omit=OMIT,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _data = typing.cast(
+                    AsyncTaskLink,
+                    parse_obj_as(
+                        type_=AsyncTaskLink,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                return HttpResponse(response=_response, data=_data)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+
+class AsyncRawDnaSequenceClient:
+    def __init__(self, *, client_wrapper: AsyncClientWrapper):
+        self._client_wrapper = client_wrapper
+
+    async def create(
+        self,
+        *,
+        bases: str,
+        folder_id: str,
+        name: str,
+        aliases: typing.Optional[typing.Sequence[str]] = OMIT,
+        annotations: typing.Optional[typing.Sequence[NucleotideAnnotationInput]] = OMIT,
+        author_ids: typing.Optional[typing.Sequence[str]] = OMIT,
+        custom_fields: typing.Optional[typing.Dict[str, FieldValueInput]] = OMIT,
+        entity_registry_id: typing.Optional[str] = OMIT,
+        is_circular: typing.Optional[bool] = OMIT,
+        naming_strategy: typing.Optional[CreateDnaSequenceInputNamingStrategy] = OMIT,
+        parts: typing.Optional[typing.Sequence[NucleotidePartInput]] = OMIT,
+        primers: typing.Optional[typing.Sequence[PrimerInput]] = OMIT,
+        registry_id: typing.Optional[str] = OMIT,
+        schema_fields: typing.Optional[typing.Dict[str, FieldValueInput]] = OMIT,
+        schema_id: typing.Optional[str] = OMIT,
+        translations: typing.Optional[typing.Sequence[TranslationInput]] = OMIT,
+        request_options: typing.Optional[RequestOptions] = None,
+    ) -> AsyncHttpResponse[DnaSequence]:
+        """
+        Create DnaSequence.
+
+        Parameters
+        ----------
+        bases : str
+            Bases of the forward strand of the DNA sequence.
+
+        folder_id : str
+
+        name : str
+            Name of the item.
+
+        aliases : typing.Optional[typing.Sequence[str]]
+            Array of aliases
+
+        annotations : typing.Optional[typing.Sequence[NucleotideAnnotationInput]]
+            Annotations on the DNA sequence, not including translations or primers. Annotations on parts are
+            not included.
+
+        author_ids : typing.Optional[typing.Sequence[str]]
+
+        custom_fields : typing.Optional[typing.Dict[str, FieldValueInput]]
+            Custom fields set on the DNA sequence.
+
+        entity_registry_id : typing.Optional[str]
+            Registry ID to assign to the entity. If one is specified, the labeling_strategy must be unspecified.
+
+        is_circular : typing.Optional[bool]
+            Whether the sequence forms a closed loop, with the last base connecting back to the first. Defaults to false if not specified.
+
+        naming_strategy : typing.Optional[CreateDnaSequenceInputNamingStrategy]
+            Strategy to use for labeling the item in the registry. If one is specified, the entity_registry_id must be unspecified.
+
+        parts : typing.Optional[typing.Sequence[NucleotidePartInput]]
+            Part features linking regions of this sequence to other nucleotide sequences.
+
+        primers : typing.Optional[typing.Sequence[PrimerInput]]
+            Primer bind features on the DNA sequence. Primers on parts are not included.
+
+        registry_id : typing.Optional[str]
+            A not null value means the entity should be registered. If not null, the value must match the registry of the item's schema.
+
+        schema_fields : typing.Optional[typing.Dict[str, FieldValueInput]]
+
+        schema_id : typing.Optional[str]
+
+        translations : typing.Optional[typing.Sequence[TranslationInput]]
+            Translation annotations present on the DNA sequence. Translations may be one region or split
+            across multiple regions. Translations on parts are not included.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        AsyncHttpResponse[DnaSequence]
+            Created
+        """
+        _response = await self._client_wrapper.httpx_client.request(
+            "api/v3/dna-sequence",
+            method="POST",
+            json={
+                "aliases": aliases,
+                "annotations": convert_and_respect_annotation_metadata(
+                    object_=annotations, annotation=typing.Sequence[NucleotideAnnotationInput], direction="write"
+                ),
+                "authorIds": author_ids,
+                "bases": bases,
+                "customFields": convert_and_respect_annotation_metadata(
+                    object_=custom_fields, annotation=typing.Dict[str, FieldValueInput], direction="write"
+                ),
+                "entityRegistryId": entity_registry_id,
+                "folderId": folder_id,
+                "isCircular": is_circular,
+                "name": name,
+                "namingStrategy": naming_strategy,
+                "parts": convert_and_respect_annotation_metadata(
+                    object_=parts, annotation=typing.Sequence[NucleotidePartInput], direction="write"
+                ),
+                "primers": convert_and_respect_annotation_metadata(
+                    object_=primers, annotation=typing.Sequence[PrimerInput], direction="write"
+                ),
+                "registryId": registry_id,
+                "schemaFields": convert_and_respect_annotation_metadata(
+                    object_=schema_fields, annotation=typing.Dict[str, FieldValueInput], direction="write"
+                ),
+                "schemaId": schema_id,
+                "translations": convert_and_respect_annotation_metadata(
+                    object_=translations, annotation=typing.Sequence[TranslationInput], direction="write"
+                ),
+            },
+            request_options=request_options,
+            omit=OMIT,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _data = typing.cast(
+                    DnaSequence,
+                    parse_obj_as(
+                        type_=DnaSequence,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                return AsyncHttpResponse(response=_response, data=_data)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    async def list(
+        self,
+        *,
+        archive_reason_any_of: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        archived_any_of: typing.Optional[typing.Union[bool, typing.Sequence[bool]]] = None,
+        authors_any_of: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        bases_any_of: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        created_at_gt: typing.Optional[str] = None,
+        created_at_gte: typing.Optional[str] = None,
+        created_at_lt: typing.Optional[str] = None,
+        created_at_lte: typing.Optional[str] = None,
+        creator_any_of: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        entity_registry_ids_any_of: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        fieldset_any_of: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        folder_eq: typing.Optional[str] = None,
+        id_any_of: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        mentioned_in_any_of: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        modified_at_gt: typing.Optional[str] = None,
+        modified_at_gte: typing.Optional[str] = None,
+        modified_at_lt: typing.Optional[str] = None,
+        modified_at_lte: typing.Optional[str] = None,
+        name_any_of: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        name_any_of_case_sensitive: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        next_token: typing.Optional[str] = None,
+        omit: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        page_size: typing.Optional[int] = None,
+        project_eq: typing.Optional[str] = None,
+        registry_eq: typing.Optional[str] = None,
+        returning: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        schema_any_of: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        schema_eq: typing.Optional[str] = None,
+        system_category_any_of: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        sort: typing.Optional[ListDnaSequenceRequestSort] = None,
+        request_options: typing.Optional[RequestOptions] = None,
+    ) -> AsyncPager[DnaSequence, DnaSequencePaginatedList]:
+        """
+        List DnaSequence items.
+
+        Parameters
+        ----------
+        archive_reason_any_of : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts items to those with any of the specified archive reasons. Use "NOT_ARCHIVED" to filter for unarchived items. Use "ANY_ARCHIVED" to filter for archived items regardless of reason. Use "ANY_ARCHIVED_OR_NOT_ARCHIVED" to return items for both archived and unarchived. Comma-separated list.
+
+        archived_any_of : typing.Optional[typing.Union[bool, typing.Sequence[bool]]]
+            If true, returns archived items. If false, returns unarchived items. If both true and false, returns archived and unarchived items. Comma-separated list.
+
+        authors_any_of : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts results to those whose author matches any of the specified user or author IDs. Comma-separated list.
+
+        bases_any_of : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts results to those whose sequence exactly matches any of the specified DNA base sequences (case-insensitive, accounting for circular and reverse complement). Comma-separated list.
+
+        created_at_gt : typing.Optional[str]
+            Datetime, in RFC 3339 format. Time zone defaults to UTC. Restricts results to those created after the specified time. e.g. > 2017-04-30.
+
+        created_at_gte : typing.Optional[str]
+            Datetime, in RFC 3339 format. Time zone defaults to UTC. Restricts results to those created at or after the specified time. e.g. >= 2017-04-30.
+
+        created_at_lt : typing.Optional[str]
+            Datetime, in RFC 3339 format. Time zone defaults to UTC. Restricts results to those created before the specified time. e.g. < 2017-04-30.
+
+        created_at_lte : typing.Optional[str]
+            Datetime, in RFC 3339 format. Time zone defaults to UTC. Restricts results to those created at or before the specified time. e.g. <= 2017-04-30.
+
+        creator_any_of : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts results to those created by any of the specified user IDs. Comma-separated list.
+
+        entity_registry_ids_any_of : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts results to those that match any of the specified entity registry IDs. Comma-separated list.
+
+        fieldset_any_of : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts results to those whose schema implements any of the specified fieldset API IDs (custom schema interfaces). Comma-separated list.
+
+        folder_eq : typing.Optional[str]
+            ID of a folder. Restricts results to its direct children.
+
+        id_any_of : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts results to those matching any of the specified IDs. Comma-separated list.
+
+        mentioned_in_any_of : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts results to items mentioned in entries matching any of the specified entry IDs. Comma-separated list.
+
+        modified_at_gt : typing.Optional[str]
+            Datetime, in RFC 3339 format. Time zone defaults to UTC. Restricts results to those modified after the specified time. e.g. > 2017-04-30.
+
+        modified_at_gte : typing.Optional[str]
+            Datetime, in RFC 3339 format. Time zone defaults to UTC. Restricts results to those modified at or after the specified time. e.g. >= 2017-04-30.
+
+        modified_at_lt : typing.Optional[str]
+            Datetime, in RFC 3339 format. Time zone defaults to UTC. Restricts results to those modified before the specified time. e.g. < 2017-04-30.
+
+        modified_at_lte : typing.Optional[str]
+            Datetime, in RFC 3339 format. Time zone defaults to UTC. Restricts results to those modified at or before the specified time. e.g. <= 2017-04-30.
+
+        name_any_of : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts results to those that match any of the specified names. Case insensitive. Warning - this filter can be non-performant due to case insensitivity. Ensure only one name filter is used at a time. Comma-separated list.
+
+        name_any_of_case_sensitive : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts results to those that match any of the specified names. Case sensitive. Ensure only one name filter is used at a time. Comma-separated list.
+
+        next_token : typing.Optional[str]
+            Token for pagination
+
+        omit : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Comma-separated list of top-level fields to omit from each returned item. Cannot overlap with returning.
+
+        page_size : typing.Optional[int]
+            Number of results to return. Defaults to 50, maximum of 100.
+
+        project_eq : typing.Optional[str]
+            ID of a project. Restricts results to those in the project.
+
+        registry_eq : typing.Optional[str]
+            ID of a registry. Restricts results to those registered in this registry. Specifying "null" returns unregistered items.
+
+        returning : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Comma-separated list of top-level fields to include in each returned item. Cannot overlap with omit.
+
+        schema_any_of : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts results to those that match any of the specified schema IDs. Use only one `schema` filter arg at a time. Comma-separated list.
+
+        schema_eq : typing.Optional[str]
+            Single schema ID. Restricts results to those that match the specified schema exactly. Use only one `schema` filter arg at a time.
+
+        system_category_any_of : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Restricts results to those whose schema implements any of the specified system category API IDs (non-exclusive static schema interfaces). Comma-separated list.
+
+        sort : typing.Optional[ListDnaSequenceRequestSort]
+            Method by which to order results. Valid sorts are: createdAt (created time, oldest first) and modifiedAt (modified time, oldest first). Use :asc or :desc to specify ascending or descending order. Default is modifiedAt:desc.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        AsyncPager[DnaSequence, DnaSequencePaginatedList]
+            OK
+        """
+        _response = await self._client_wrapper.httpx_client.request(
+            "api/v3/dna-sequence/items",
+            method="GET",
+            params={
+                "archiveReason.anyOf": ",".join(map(str, archive_reason_any_of))
+                if isinstance(archive_reason_any_of, (list, tuple, set))
+                else archive_reason_any_of,
+                "archived.anyOf": ",".join(map(str, archived_any_of))
+                if isinstance(archived_any_of, (list, tuple, set))
+                else archived_any_of,
+                "authors.anyOf": ",".join(map(str, authors_any_of))
+                if isinstance(authors_any_of, (list, tuple, set))
+                else authors_any_of,
+                "bases.anyOf": ",".join(map(str, bases_any_of))
+                if isinstance(bases_any_of, (list, tuple, set))
+                else bases_any_of,
+                "createdAt.gt": created_at_gt,
+                "createdAt.gte": created_at_gte,
+                "createdAt.lt": created_at_lt,
+                "createdAt.lte": created_at_lte,
+                "creator.anyOf": ",".join(map(str, creator_any_of))
+                if isinstance(creator_any_of, (list, tuple, set))
+                else creator_any_of,
+                "entityRegistryIds.anyOf": ",".join(map(str, entity_registry_ids_any_of))
+                if isinstance(entity_registry_ids_any_of, (list, tuple, set))
+                else entity_registry_ids_any_of,
+                "fieldset.anyOf": ",".join(map(str, fieldset_any_of))
+                if isinstance(fieldset_any_of, (list, tuple, set))
+                else fieldset_any_of,
+                "folder.eq": folder_eq,
+                "id.anyOf": ",".join(map(str, id_any_of)) if isinstance(id_any_of, (list, tuple, set)) else id_any_of,
+                "mentionedIn.anyOf": ",".join(map(str, mentioned_in_any_of))
+                if isinstance(mentioned_in_any_of, (list, tuple, set))
+                else mentioned_in_any_of,
+                "modifiedAt.gt": modified_at_gt,
+                "modifiedAt.gte": modified_at_gte,
+                "modifiedAt.lt": modified_at_lt,
+                "modifiedAt.lte": modified_at_lte,
+                "name.anyOf": ",".join(map(str, name_any_of))
+                if isinstance(name_any_of, (list, tuple, set))
+                else name_any_of,
+                "name.anyOf.caseSensitive": ",".join(map(str, name_any_of_case_sensitive))
+                if isinstance(name_any_of_case_sensitive, (list, tuple, set))
+                else name_any_of_case_sensitive,
+                "nextToken": next_token,
+                "omit": ",".join(map(str, omit)) if isinstance(omit, (list, tuple, set)) else omit,
+                "pageSize": page_size,
+                "project.eq": project_eq,
+                "registry.eq": registry_eq,
+                "returning": ",".join(map(str, returning)) if isinstance(returning, (list, tuple, set)) else returning,
+                "schema.anyOf": ",".join(map(str, schema_any_of))
+                if isinstance(schema_any_of, (list, tuple, set))
+                else schema_any_of,
+                "schema.eq": schema_eq,
+                "systemCategory.anyOf": ",".join(map(str, system_category_any_of))
+                if isinstance(system_category_any_of, (list, tuple, set))
+                else system_category_any_of,
+                "sort": sort,
+            },
+            request_options=request_options,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _parsed_response = typing.cast(
+                    DnaSequencePaginatedList,
+                    parse_obj_as(
+                        type_=DnaSequencePaginatedList,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                _items = _parsed_response.items
+                _parsed_next = _parsed_response.next_token
+                _has_next = _parsed_next is not None and _parsed_next != ""
+
+                async def _get_next():
+                    return await self.list(
+                        archive_reason_any_of=archive_reason_any_of,
+                        archived_any_of=archived_any_of,
+                        authors_any_of=authors_any_of,
+                        bases_any_of=bases_any_of,
+                        created_at_gt=created_at_gt,
+                        created_at_gte=created_at_gte,
+                        created_at_lt=created_at_lt,
+                        created_at_lte=created_at_lte,
+                        creator_any_of=creator_any_of,
+                        entity_registry_ids_any_of=entity_registry_ids_any_of,
+                        fieldset_any_of=fieldset_any_of,
+                        folder_eq=folder_eq,
+                        id_any_of=id_any_of,
+                        mentioned_in_any_of=mentioned_in_any_of,
+                        modified_at_gt=modified_at_gt,
+                        modified_at_gte=modified_at_gte,
+                        modified_at_lt=modified_at_lt,
+                        modified_at_lte=modified_at_lte,
+                        name_any_of=name_any_of,
+                        name_any_of_case_sensitive=name_any_of_case_sensitive,
+                        next_token=_parsed_next,
+                        omit=omit,
+                        page_size=page_size,
+                        project_eq=project_eq,
+                        registry_eq=registry_eq,
+                        returning=returning,
+                        schema_any_of=schema_any_of,
+                        schema_eq=schema_eq,
+                        system_category_any_of=system_category_any_of,
+                        sort=sort,
+                        request_options=request_options,
+                    )
+
+                return AsyncPager(has_next=_has_next, items=_items, get_next=_get_next, response=_parsed_response)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    async def get(
+        self,
+        dna_sequence_id: str,
+        *,
+        returning: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        omit: typing.Optional[typing.Union[str, typing.Sequence[str]]] = None,
+        request_options: typing.Optional[RequestOptions] = None,
+    ) -> AsyncHttpResponse[DnaSequence]:
+        """
+        Get a single DnaSequence by ID.
+
+        Parameters
+        ----------
+        dna_sequence_id : str
+            ID of the DnaSequence.
+
+        returning : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Comma-separated list of top-level fields to include in each returned item. Cannot overlap with omit.
+
+        omit : typing.Optional[typing.Union[str, typing.Sequence[str]]]
+            Comma-separated list of top-level fields to omit from each returned item. Cannot overlap with returning.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        AsyncHttpResponse[DnaSequence]
+            OK
+        """
+        _response = await self._client_wrapper.httpx_client.request(
+            f"api/v3/dna-sequence/{encode_path_param(dna_sequence_id)}",
+            method="GET",
+            params={
+                "returning": ",".join(map(str, returning)) if isinstance(returning, (list, tuple, set)) else returning,
+                "omit": ",".join(map(str, omit)) if isinstance(omit, (list, tuple, set)) else omit,
+            },
+            request_options=request_options,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _data = typing.cast(
+                    DnaSequence,
+                    parse_obj_as(
+                        type_=DnaSequence,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                return AsyncHttpResponse(response=_response, data=_data)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    async def update(
+        self,
+        dna_sequence_id: str,
+        *,
+        aliases: typing.Optional[typing.Sequence[str]] = OMIT,
+        annotations: typing.Optional[typing.Sequence[NucleotideAnnotationInput]] = OMIT,
+        archive_reason: typing.Optional[str] = OMIT,
+        archived: typing.Optional[bool] = OMIT,
+        author_ids: typing.Optional[typing.Sequence[str]] = OMIT,
+        bases: typing.Optional[str] = OMIT,
+        custom_fields: typing.Optional[typing.Dict[str, FieldValueInput]] = OMIT,
+        entity_registry_id: typing.Optional[str] = OMIT,
+        folder_id: typing.Optional[str] = OMIT,
+        is_circular: typing.Optional[bool] = OMIT,
+        name: typing.Optional[str] = OMIT,
+        naming_strategy: typing.Optional[UpdateDnaSequenceInputNamingStrategy] = OMIT,
+        parts: typing.Optional[typing.Sequence[NucleotidePartInput]] = OMIT,
+        primers: typing.Optional[typing.Sequence[PrimerInput]] = OMIT,
+        registry_id: typing.Optional[str] = OMIT,
+        schema_fields: typing.Optional[typing.Dict[str, FieldValueInput]] = OMIT,
+        schema_id: typing.Optional[str] = OMIT,
+        translations: typing.Optional[typing.Sequence[TranslationInput]] = OMIT,
+        request_options: typing.Optional[RequestOptions] = None,
+    ) -> AsyncHttpResponse[DnaSequence]:
+        """
+        Update a DNA sequence. The `id` path parameter identifies the DNA sequence to update.
+
+        ## Updating bases
+
+        When replacing `bases`, include every sequence feature collection that already exists on the sequence: `annotations`, `translations`, `primers`, and `parts`. Provide the updated values or an empty array (`[]`) to clear a collection. Omitting a key that has existing data returns `400`.
+
+        Parameters
+        ----------
+        dna_sequence_id : str
+            ID of the DnaSequence.
+
+        aliases : typing.Optional[typing.Sequence[str]]
+            Array of aliases
+
+        annotations : typing.Optional[typing.Sequence[NucleotideAnnotationInput]]
+            Annotations on the DNA sequence, not including translations or primers. Annotations on parts are
+            not included.
+
+        archive_reason : typing.Optional[str]
+
+        archived : typing.Optional[bool]
+
+        author_ids : typing.Optional[typing.Sequence[str]]
+
+        bases : typing.Optional[str]
+            Bases of the forward strand of the DNA sequence.
+
+        custom_fields : typing.Optional[typing.Dict[str, FieldValueInput]]
+            Custom fields set on the DNA sequence.
+
+        entity_registry_id : typing.Optional[str]
+            Registry ID to assign to the entity. When registering, specifying this value sets the registry ID of the entity. When already registered, specifying this value updates the entity's registry ID. If set, naming_strategy must be unspecified.
+
+        folder_id : typing.Optional[str]
+
+        is_circular : typing.Optional[bool]
+            Whether the sequence forms a closed loop, with the last base connecting back to the first. Defaults to false if not specified.
+
+        name : typing.Optional[str]
+            Name of the item.
+
+        naming_strategy : typing.Optional[UpdateDnaSequenceInputNamingStrategy]
+            Strategy to use for labeling the item in the registry if registering. If one is specified, the entity_registry_id must be unspecified.
+
+        parts : typing.Optional[typing.Sequence[NucleotidePartInput]]
+            Part features linking regions of this sequence to other nucleotide sequences.
+
+        primers : typing.Optional[typing.Sequence[PrimerInput]]
+            Primer bind features on the DNA sequence. Primers on parts are not included.
+
+        registry_id : typing.Optional[str]
+            A not null value means the entity should be registered. A null value means it should be unregistered. If not null, the value must match the registry of the item's schema.
+
+        schema_fields : typing.Optional[typing.Dict[str, FieldValueInput]]
+
+        schema_id : typing.Optional[str]
+
+        translations : typing.Optional[typing.Sequence[TranslationInput]]
+            Translation annotations present on the DNA sequence. Translations may be one region or split
+            across multiple regions. Translations on parts are not included.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        AsyncHttpResponse[DnaSequence]
+            OK
+        """
+        _response = await self._client_wrapper.httpx_client.request(
+            f"api/v3/dna-sequence/{encode_path_param(dna_sequence_id)}",
+            method="PATCH",
+            json={
+                "aliases": aliases,
+                "annotations": convert_and_respect_annotation_metadata(
+                    object_=annotations, annotation=typing.Sequence[NucleotideAnnotationInput], direction="write"
+                ),
+                "archiveReason": archive_reason,
+                "archived": archived,
+                "authorIds": author_ids,
+                "bases": bases,
+                "customFields": convert_and_respect_annotation_metadata(
+                    object_=custom_fields, annotation=typing.Dict[str, FieldValueInput], direction="write"
+                ),
+                "entityRegistryId": entity_registry_id,
+                "folderId": folder_id,
+                "isCircular": is_circular,
+                "name": name,
+                "namingStrategy": naming_strategy,
+                "parts": convert_and_respect_annotation_metadata(
+                    object_=parts, annotation=typing.Sequence[NucleotidePartInput], direction="write"
+                ),
+                "primers": convert_and_respect_annotation_metadata(
+                    object_=primers, annotation=typing.Sequence[PrimerInput], direction="write"
+                ),
+                "registryId": registry_id,
+                "schemaFields": convert_and_respect_annotation_metadata(
+                    object_=schema_fields, annotation=typing.Dict[str, FieldValueInput], direction="write"
+                ),
+                "schemaId": schema_id,
+                "translations": convert_and_respect_annotation_metadata(
+                    object_=translations, annotation=typing.Sequence[TranslationInput], direction="write"
+                ),
+            },
+            headers={
+                "content-type": "application/json",
+            },
+            request_options=request_options,
+            omit=OMIT,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _data = typing.cast(
+                    DnaSequence,
+                    parse_obj_as(
+                        type_=DnaSequence,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                return AsyncHttpResponse(response=_response, data=_data)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    async def list_annotations(
+        self,
+        dna_sequence_id: str,
+        *,
+        next_token: typing.Optional[str] = None,
+        page_size: typing.Optional[int] = None,
+        request_options: typing.Optional[RequestOptions] = None,
+    ) -> AsyncPager[NucleotideAnnotation, NucleotideAnnotationPaginatedList]:
+        """
+        List NucleotideAnnotation items.
+
+        Parameters
+        ----------
+        dna_sequence_id : str
+            ID of the DnaSequence.
+
+        next_token : typing.Optional[str]
+            Token for pagination
+
+        page_size : typing.Optional[int]
+            Number of results to return. Defaults to 50, maximum of 100.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        AsyncPager[NucleotideAnnotation, NucleotideAnnotationPaginatedList]
+            OK
+        """
+        _response = await self._client_wrapper.httpx_client.request(
+            f"api/v3/dna-sequence/{encode_path_param(dna_sequence_id)}/annotations/items",
+            method="GET",
+            params={
+                "nextToken": next_token,
+                "pageSize": page_size,
+            },
+            request_options=request_options,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _parsed_response = typing.cast(
+                    NucleotideAnnotationPaginatedList,
+                    parse_obj_as(
+                        type_=NucleotideAnnotationPaginatedList,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                _items = _parsed_response.items
+                _parsed_next = _parsed_response.next_token
+                _has_next = _parsed_next is not None and _parsed_next != ""
+
+                async def _get_next():
+                    return await self.list_annotations(
+                        dna_sequence_id,
+                        next_token=_parsed_next,
+                        page_size=page_size,
+                        request_options=request_options,
+                    )
+
+                return AsyncPager(has_next=_has_next, items=_items, get_next=_get_next, response=_parsed_response)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    async def list_authors(
+        self, dna_sequence_id: str, *, request_options: typing.Optional[RequestOptions] = None
+    ) -> AsyncHttpResponse[PrincipalUnpaginatedList]:
+        """
+        List Principal items.
+
+        Parameters
+        ----------
+        dna_sequence_id : str
+            ID of the DnaSequence.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        AsyncHttpResponse[PrincipalUnpaginatedList]
+            OK
+        """
+        _response = await self._client_wrapper.httpx_client.request(
+            f"api/v3/dna-sequence/{encode_path_param(dna_sequence_id)}/authors/items",
+            method="GET",
+            request_options=request_options,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _data = typing.cast(
+                    PrincipalUnpaginatedList,
+                    parse_obj_as(
+                        type_=PrincipalUnpaginatedList,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                return AsyncHttpResponse(response=_response, data=_data)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    async def list_nucleotide_alignments(
+        self, dna_sequence_id: str, *, request_options: typing.Optional[RequestOptions] = None
+    ) -> AsyncHttpResponse[NucleotideAlignmentUnpaginatedList]:
+        """
+        List NucleotideAlignment items.
+
+        Parameters
+        ----------
+        dna_sequence_id : str
+            ID of the DnaSequence.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        AsyncHttpResponse[NucleotideAlignmentUnpaginatedList]
+            OK
+        """
+        _response = await self._client_wrapper.httpx_client.request(
+            f"api/v3/dna-sequence/{encode_path_param(dna_sequence_id)}/nucleotide-alignments/items",
+            method="GET",
+            request_options=request_options,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _data = typing.cast(
+                    NucleotideAlignmentUnpaginatedList,
+                    parse_obj_as(
+                        type_=NucleotideAlignmentUnpaginatedList,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                return AsyncHttpResponse(response=_response, data=_data)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    async def list_parts(
+        self,
+        dna_sequence_id: str,
+        *,
+        next_token: typing.Optional[str] = None,
+        page_size: typing.Optional[int] = None,
+        request_options: typing.Optional[RequestOptions] = None,
+    ) -> AsyncPager[DnaPart, DnaPartPaginatedList]:
+        """
+        List DnaPart items.
+
+        Parameters
+        ----------
+        dna_sequence_id : str
+            ID of the DnaSequence.
+
+        next_token : typing.Optional[str]
+            Token for pagination
+
+        page_size : typing.Optional[int]
+            Number of results to return. Defaults to 50, maximum of 100.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        AsyncPager[DnaPart, DnaPartPaginatedList]
+            OK
+        """
+        _response = await self._client_wrapper.httpx_client.request(
+            f"api/v3/dna-sequence/{encode_path_param(dna_sequence_id)}/parts/items",
+            method="GET",
+            params={
+                "nextToken": next_token,
+                "pageSize": page_size,
+            },
+            request_options=request_options,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _parsed_response = typing.cast(
+                    DnaPartPaginatedList,
+                    parse_obj_as(
+                        type_=DnaPartPaginatedList,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                _items = _parsed_response.items
+                _parsed_next = _parsed_response.next_token
+                _has_next = _parsed_next is not None and _parsed_next != ""
+
+                async def _get_next():
+                    return await self.list_parts(
+                        dna_sequence_id,
+                        next_token=_parsed_next,
+                        page_size=page_size,
+                        request_options=request_options,
+                    )
+
+                return AsyncPager(has_next=_has_next, items=_items, get_next=_get_next, response=_parsed_response)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    async def list_primers(
+        self,
+        dna_sequence_id: str,
+        *,
+        next_token: typing.Optional[str] = None,
+        page_size: typing.Optional[int] = None,
+        request_options: typing.Optional[RequestOptions] = None,
+    ) -> AsyncPager[Primer, PrimerPaginatedList]:
+        """
+        List Primer items.
+
+        Parameters
+        ----------
+        dna_sequence_id : str
+            ID of the DnaSequence.
+
+        next_token : typing.Optional[str]
+            Token for pagination
+
+        page_size : typing.Optional[int]
+            Number of results to return. Defaults to 50, maximum of 100.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        AsyncPager[Primer, PrimerPaginatedList]
+            OK
+        """
+        _response = await self._client_wrapper.httpx_client.request(
+            f"api/v3/dna-sequence/{encode_path_param(dna_sequence_id)}/primers/items",
+            method="GET",
+            params={
+                "nextToken": next_token,
+                "pageSize": page_size,
+            },
+            request_options=request_options,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _parsed_response = typing.cast(
+                    PrimerPaginatedList,
+                    parse_obj_as(
+                        type_=PrimerPaginatedList,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                _items = _parsed_response.items
+                _parsed_next = _parsed_response.next_token
+                _has_next = _parsed_next is not None and _parsed_next != ""
+
+                async def _get_next():
+                    return await self.list_primers(
+                        dna_sequence_id,
+                        next_token=_parsed_next,
+                        page_size=page_size,
+                        request_options=request_options,
+                    )
+
+                return AsyncPager(has_next=_has_next, items=_items, get_next=_get_next, response=_parsed_response)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    async def list_translations(
+        self,
+        dna_sequence_id: str,
+        *,
+        next_token: typing.Optional[str] = None,
+        page_size: typing.Optional[int] = None,
+        request_options: typing.Optional[RequestOptions] = None,
+    ) -> AsyncPager[Translation, TranslationPaginatedList]:
+        """
+        List Translation items.
+
+        Parameters
+        ----------
+        dna_sequence_id : str
+            ID of the DnaSequence.
+
+        next_token : typing.Optional[str]
+            Token for pagination
+
+        page_size : typing.Optional[int]
+            Number of results to return. Defaults to 50, maximum of 100.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        AsyncPager[Translation, TranslationPaginatedList]
+            OK
+        """
+        _response = await self._client_wrapper.httpx_client.request(
+            f"api/v3/dna-sequence/{encode_path_param(dna_sequence_id)}/translations/items",
+            method="GET",
+            params={
+                "nextToken": next_token,
+                "pageSize": page_size,
+            },
+            request_options=request_options,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _parsed_response = typing.cast(
+                    TranslationPaginatedList,
+                    parse_obj_as(
+                        type_=TranslationPaginatedList,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                _items = _parsed_response.items
+                _parsed_next = _parsed_response.next_token
+                _has_next = _parsed_next is not None and _parsed_next != ""
+
+                async def _get_next():
+                    return await self.list_translations(
+                        dna_sequence_id,
+                        next_token=_parsed_next,
+                        page_size=page_size,
+                        request_options=request_options,
+                    )
+
+                return AsyncPager(has_next=_has_next, items=_items, get_next=_get_next, response=_parsed_response)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    async def batch_create(
+        self, *, items: typing.Sequence[CreateDnaSequenceInput], request_options: typing.Optional[RequestOptions] = None
+    ) -> AsyncHttpResponse[BatchCreateDnaSequenceResponse]:
+        """
+        Batch create DnaSequence synchronously in one transaction. Maximum 25 items per request.
+
+        Parameters
+        ----------
+        items : typing.Sequence[CreateDnaSequenceInput]
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        AsyncHttpResponse[BatchCreateDnaSequenceResponse]
+            Created
+        """
+        _response = await self._client_wrapper.httpx_client.request(
+            "api/v3/dna-sequence:batch-create",
+            method="POST",
+            json={
+                "items": convert_and_respect_annotation_metadata(
+                    object_=items, annotation=typing.Sequence[CreateDnaSequenceInput], direction="write"
+                ),
+            },
+            headers={
+                "content-type": "application/json",
+            },
+            request_options=request_options,
+            omit=OMIT,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _data = typing.cast(
+                    BatchCreateDnaSequenceResponse,
+                    parse_obj_as(
+                        type_=BatchCreateDnaSequenceResponse,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                return AsyncHttpResponse(response=_response, data=_data)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    async def batch_update(
+        self,
+        *,
+        items: typing.Sequence[UpdateDnaSequenceInputWithPathParams],
+        request_options: typing.Optional[RequestOptions] = None,
+    ) -> AsyncHttpResponse[BatchUpdateDnaSequenceResponse]:
+        """
+        Batch update DnaSequence synchronously in one transaction. Maximum 25 items per request.
+
+        Parameters
+        ----------
+        items : typing.Sequence[UpdateDnaSequenceInputWithPathParams]
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        AsyncHttpResponse[BatchUpdateDnaSequenceResponse]
+            OK
+        """
+        _response = await self._client_wrapper.httpx_client.request(
+            "api/v3/dna-sequence:batch-update",
+            method="PATCH",
+            json={
+                "items": convert_and_respect_annotation_metadata(
+                    object_=items, annotation=typing.Sequence[UpdateDnaSequenceInputWithPathParams], direction="write"
+                ),
+            },
+            headers={
+                "content-type": "application/json",
+            },
+            request_options=request_options,
+            omit=OMIT,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _data = typing.cast(
+                    BatchUpdateDnaSequenceResponse,
+                    parse_obj_as(
+                        type_=BatchUpdateDnaSequenceResponse,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                return AsyncHttpResponse(response=_response, data=_data)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    async def bulk_create(
+        self, *, file_id: str, request_options: typing.Optional[RequestOptions] = None
+    ) -> AsyncHttpResponse[AsyncTaskLink]:
+        """
+        Bulk create DnaSequence.
+
+        Parameters
+        ----------
+        file_id : str
+            The API ID of the scratch file (`scrfile_XXXXXXXX`) containing the items to import. The referenced file must be a scratch file whose upload has completed successfully.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        AsyncHttpResponse[AsyncTaskLink]
+            Task started
+        """
+        _response = await self._client_wrapper.httpx_client.request(
+            "api/v3/dna-sequence:bulk-create",
+            method="POST",
+            json={
+                "fileId": file_id,
+            },
+            request_options=request_options,
+            omit=OMIT,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _data = typing.cast(
+                    AsyncTaskLink,
+                    parse_obj_as(
+                        type_=AsyncTaskLink,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                return AsyncHttpResponse(response=_response, data=_data)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)
+
+    async def bulk_update(
+        self, *, file_id: str, request_options: typing.Optional[RequestOptions] = None
+    ) -> AsyncHttpResponse[AsyncTaskLink]:
+        """
+        Bulk update DnaSequence.
+
+        Parameters
+        ----------
+        file_id : str
+            The API ID of the scratch file (`scrfile_XXXXXXXX`) containing the items to import. The referenced file must be a scratch file whose upload has completed successfully.
+
+        request_options : typing.Optional[RequestOptions]
+            Request-specific configuration.
+
+        Returns
+        -------
+        AsyncHttpResponse[AsyncTaskLink]
+            Task started
+        """
+        _response = await self._client_wrapper.httpx_client.request(
+            "api/v3/dna-sequence:bulk-update",
+            method="PATCH",
+            json={
+                "fileId": file_id,
+            },
+            request_options=request_options,
+            omit=OMIT,
+        )
+        try:
+            if 200 <= _response.status_code < 300:
+                _data = typing.cast(
+                    AsyncTaskLink,
+                    parse_obj_as(
+                        type_=AsyncTaskLink,  # type: ignore
+                        object_=_response.json(),
+                    ),
+                )
+                return AsyncHttpResponse(response=_response, data=_data)
+            if _response.status_code == 400:
+                raise BadRequestError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        typing.Any,
+                        parse_obj_as(
+                            type_=typing.Any,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 403:
+                raise ForbiddenError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 404:
+                raise NotFoundError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 429:
+                raise TooManyRequestsError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        GeneralError,
+                        parse_obj_as(
+                            type_=GeneralError,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            if _response.status_code == 500:
+                raise InternalServerError(
+                    headers=dict(_response.headers),
+                    body=typing.cast(
+                        InternalServerErrorBody,
+                        parse_obj_as(
+                            type_=InternalServerErrorBody,  # type: ignore
+                            object_=_response.json(),
+                        ),
+                    ),
+                )
+            _response_json = _response.json()
+        except JSONDecodeError:
+            raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response.text)
+        except ValidationError as e:
+            raise ParsingError(
+                status_code=_response.status_code, headers=dict(_response.headers), body=_response.json(), cause=e
+            )
+        raise ApiError(status_code=_response.status_code, headers=dict(_response.headers), body=_response_json)