heor-agent-mcp 0.1.0

package/dist/providers/direct/bnf.js

@@ -0,0 +1,30 @@
+export async function fetchBnf(query, maxResults) {
+    const entries = [
+        {
+            title: `BNF Drug Pricing: ${query}`,
+            abstract: `The British National Formulary (BNF) is the authoritative UK drug reference, including prices, dosing, indications, and contraindications. For "${query}", search the NICE BNF website. NHS list prices are used as the primary drug cost input in NICE economic models. Prices are updated monthly.`,
+            url: `https://bnf.nice.org.uk/search/?q=${encodeURIComponent(query)}`,
+        },
+        {
+            title: `NHS Drug Tariff — Community Pharmacy Prices`,
+            abstract: `NHS Business Services Authority publishes the monthly Drug Tariff with reimbursement prices paid to community pharmacies for drugs dispensed in primary care. Complementary to BNF for understanding community prescribing costs.`,
+            url: "https://www.nhsbsa.nhs.uk/pharmacies-gp-practices-and-appliance-contractors/drug-tariff",
+        },
+        {
+            title: `Electronic Medicines Compendium (emc)`,
+            abstract: `Free access to Summary of Product Characteristics (SmPC) and Patient Information Leaflets (PILs) for UK-licensed medicines. Required for confirming indications and dosing when building cost models.`,
+            url: `https://www.medicines.org.uk/emc/search?q=${encodeURIComponent(query)}`,
+        },
+    ];
+    return entries.slice(0, maxResults).map((e, i) => ({
+        id: `bnf_${i}`,
+        source: "bnf",
+        title: e.title,
+        authors: ["Joint Formulary Committee (BMJ Group & Royal Pharmaceutical Society)"],
+        date: new Date().getFullYear().toString(),
+        study_type: "drug_pricing",
+        abstract: e.abstract,
+        url: e.url,
+    }));
+}
+//# sourceMappingURL=bnf.js.map

package/dist/providers/direct/bnf.js.map

@@ -0,0 +1 @@
+{"version":3,"file":"bnf.js","sourceRoot":"","sources":["../../../src/providers/direct/bnf.ts"],"names":[],"mappings":"AAEA,MAAM,CAAC,KAAK,UAAU,QAAQ,CAAC,KAAa,EAAE,UAAkB;IAC9D,MAAM,OAAO,GAAG;QACd;YACE,KAAK,EAAE,qBAAqB,KAAK,EAAE;YACnC,QAAQ,EAAE,mJAAmJ,KAAK,8IAA8I;YAChT,GAAG,EAAE,qCAAqC,kBAAkB,CAAC,KAAK,CAAC,EAAE;SACtE;QACD;YACE,KAAK,EAAE,6CAA6C;YACpD,QAAQ,EAAE,mOAAmO;YAC7O,GAAG,EAAE,yFAAyF;SAC/F;QACD;YACE,KAAK,EAAE,uCAAuC;YAC9C,QAAQ,EAAE,uMAAuM;YACjN,GAAG,EAAE,6CAA6C,kBAAkB,CAAC,KAAK,CAAC,EAAE;SAC9E;KACF,CAAC;IAEF,OAAO,OAAO,CAAC,KAAK,CAAC,CAAC,EAAE,UAAU,CAAC,CAAC,GAAG,CAAC,CAAC,CAAC,EAAE,CAAC,EAAE,EAAE,CAAC,CAAC;QACjD,EAAE,EAAE,OAAO,CAAC,EAAE;QACd,MAAM,EAAE,KAAc;QACtB,KAAK,EAAE,CAAC,CAAC,KAAK;QACd,OAAO,EAAE,CAAC,sEAAsE,CAAC;QACjF,IAAI,EAAE,IAAI,IAAI,EAAE,CAAC,WAAW,EAAE,CAAC,QAAQ,EAAE;QACzC,UAAU,EAAE,cAAc;QAC1B,QAAQ,EAAE,CAAC,CAAC,QAAQ;QACpB,GAAG,EAAE,CAAC,CAAC,GAAG;KACX,CAAC,CAAC,CAAC;AACN,CAAC"}

package/dist/providers/direct/cadthReviews.d.ts

@@ -0,0 +1,3 @@
+import type { LiteratureResult } from "../types.js";
+export declare function fetchCadthReviews(query: string, maxResults: number): Promise<LiteratureResult[]>;
+//# sourceMappingURL=cadthReviews.d.ts.map

package/dist/providers/direct/cadthReviews.d.ts.map

@@ -0,0 +1 @@
+{"version":3,"file":"cadthReviews.d.ts","sourceRoot":"","sources":["../../../src/providers/direct/cadthReviews.ts"],"names":[],"mappings":"AAAA,OAAO,KAAK,EAAE,gBAAgB,EAAE,MAAM,aAAa,CAAC;AAEpD,wBAAsB,iBAAiB,CAAC,KAAK,EAAE,MAAM,EAAE,UAAU,EAAE,MAAM,GAAG,OAAO,CAAC,gBAAgB,EAAE,CAAC,CA6BtG"}

package/dist/providers/direct/cadthReviews.js

@@ -0,0 +1,30 @@
+export async function fetchCadthReviews(query, maxResults) {
+    const entries = [
+        {
+            title: `CADTH CDR (Common Drug Review) Reports: ${query}`,
+            abstract: `CADTH's Common Drug Review (CDR) and pan-Canadian Oncology Drug Review (pCODR) provide independent health technology assessments for reimbursement decisions across Canadian provinces. Each review includes clinical evidence summary, pharmacoeconomic review, and formulary recommendations. Search "${query}" to find past CDR/pCODR decisions relevant to the drug or indication. Key for benchmarking Canadian market access strategy and understanding CADTH's evidence standards.`,
+            url: `https://www.cadth.ca/reimbursement-reviews-search?search_api_fulltext=${encodeURIComponent(query)}`,
+        },
+        {
+            title: `CADTH Pan-Canadian Oncology Drug Review (pCODR)`,
+            abstract: `pCODR reviews oncology drugs for reimbursement across Canada. Includes initial and resubmission reviews with clinical and pharmacoeconomic summaries, expert committee recommendations, and pan-Canadian reimbursement conditions. Essential for oncology HTA submissions targeting Canadian payers.`,
+            url: "https://www.cadth.ca/pcodr",
+        },
+        {
+            title: `CADTH Methods and Guidelines`,
+            abstract: `CADTH's methodological guidelines for health technology assessments, including pharmacoeconomic guidelines for Canada. Covers modelling standards, utility values, costs, willingness-to-pay thresholds, and indirect treatment comparisons. Required reference for preparing Canadian HTA submissions.`,
+            url: "https://www.cadth.ca/methods-and-guidelines",
+        },
+    ];
+    return entries.slice(0, maxResults).map((e, i) => ({
+        id: `cadth_reviews_${i}`,
+        source: "cadth_reviews",
+        title: e.title,
+        authors: ["CADTH — Canadian Agency for Drugs and Technologies in Health"],
+        date: new Date().getFullYear().toString(),
+        study_type: "hta_report",
+        abstract: e.abstract,
+        url: e.url,
+    }));
+}
+//# sourceMappingURL=cadthReviews.js.map

package/dist/providers/direct/cadthReviews.js.map

@@ -0,0 +1 @@
+{"version":3,"file":"cadthReviews.js","sourceRoot":"","sources":["../../../src/providers/direct/cadthReviews.ts"],"names":[],"mappings":"AAEA,MAAM,CAAC,KAAK,UAAU,iBAAiB,CAAC,KAAa,EAAE,UAAkB;IACvE,MAAM,OAAO,GAAG;QACd;YACE,KAAK,EAAE,2CAA2C,KAAK,EAAE;YACzD,QAAQ,EAAE,2SAA2S,KAAK,2KAA2K;YACre,GAAG,EAAE,yEAAyE,kBAAkB,CAAC,KAAK,CAAC,EAAE;SAC1G;QACD;YACE,KAAK,EAAE,iDAAiD;YACxD,QAAQ,EAAE,sSAAsS;YAChT,GAAG,EAAE,4BAA4B;SAClC;QACD;YACE,KAAK,EAAE,8BAA8B;YACrC,QAAQ,EAAE,ySAAyS;YACnT,GAAG,EAAE,6CAA6C;SACnD;KACF,CAAC;IAEF,OAAO,OAAO,CAAC,KAAK,CAAC,CAAC,EAAE,UAAU,CAAC,CAAC,GAAG,CAAC,CAAC,CAAC,EAAE,CAAC,EAAE,EAAE,CAAC,CAAC;QACjD,EAAE,EAAE,iBAAiB,CAAC,EAAE;QACxB,MAAM,EAAE,eAAwB;QAChC,KAAK,EAAE,CAAC,CAAC,KAAK;QACd,OAAO,EAAE,CAAC,8DAA8D,CAAC;QACzE,IAAI,EAAE,IAAI,IAAI,EAAE,CAAC,WAAW,EAAE,CAAC,QAAQ,EAAE;QACzC,UAAU,EAAE,YAAY;QACxB,QAAQ,EAAE,CAAC,CAAC,QAAQ;QACpB,GAAG,EAAE,CAAC,CAAC,GAAG;KACX,CAAC,CAAC,CAAC;AACN,CAAC"}

package/dist/providers/direct/chembl.d.ts

@@ -0,0 +1,3 @@
+import type { LiteratureResult } from "../types.js";
+export declare function fetchChembl(query: string, maxResults: number): Promise<LiteratureResult[]>;
+//# sourceMappingURL=chembl.d.ts.map

package/dist/providers/direct/chembl.d.ts.map

@@ -0,0 +1 @@
+{"version":3,"file":"chembl.d.ts","sourceRoot":"","sources":["../../../src/providers/direct/chembl.ts"],"names":[],"mappings":"AAAA,OAAO,KAAK,EAAE,gBAAgB,EAAE,MAAM,aAAa,CAAC;AAYpD,wBAAsB,WAAW,CAAC,KAAK,EAAE,MAAM,EAAE,UAAU,EAAE,MAAM,GAAG,OAAO,CAAC,gBAAgB,EAAE,CAAC,CAoBhG"}

package/dist/providers/direct/chembl.js

@@ -0,0 +1,24 @@
+const BASE = "https://www.ebi.ac.uk/chembl/api/data";
+export async function fetchChembl(query, maxResults) {
+    try {
+        const url = `${BASE}/molecule.json?pref_name__icontains=${encodeURIComponent(query)}&limit=${maxResults}`;
+        const res = await fetch(url);
+        if (!res.ok)
+            return [];
+        const data = await res.json();
+        return (data.molecules ?? []).map((mol) => ({
+            id: `chembl_${mol.molecule_chembl_id}`,
+            source: "chembl",
+            title: mol.pref_name ?? mol.molecule_chembl_id,
+            authors: [],
+            date: mol.first_approval ? `${mol.first_approval}` : "",
+            study_type: "compound_data",
+            abstract: `${mol.molecule_type ?? "Molecule"} — MW: ${mol.molecule_properties?.full_mwt ?? "unknown"}`,
+            url: `https://www.ebi.ac.uk/chembl/compound_report_card/${mol.molecule_chembl_id}/`,
+        }));
+    }
+    catch {
+        return [];
+    }
+}
+//# sourceMappingURL=chembl.js.map

package/dist/providers/direct/chembl.js.map

@@ -0,0 +1 @@
+{"version":3,"file":"chembl.js","sourceRoot":"","sources":["../../../src/providers/direct/chembl.ts"],"names":[],"mappings":"AAEA,MAAM,IAAI,GAAG,uCAAuC,CAAC;AAUrD,MAAM,CAAC,KAAK,UAAU,WAAW,CAAC,KAAa,EAAE,UAAkB;IACjE,IAAI,CAAC;QACH,MAAM,GAAG,GAAG,GAAG,IAAI,uCAAuC,kBAAkB,CAAC,KAAK,CAAC,UAAU,UAAU,EAAE,CAAC;QAC1G,MAAM,GAAG,GAAG,MAAM,KAAK,CAAC,GAAG,CAAC,CAAC;QAC7B,IAAI,CAAC,GAAG,CAAC,EAAE;YAAE,OAAO,EAAE,CAAC;QAEvB,MAAM,IAAI,GAAG,MAAM,GAAG,CAAC,IAAI,EAAqC,CAAC;QACjE,OAAO,CAAC,IAAI,CAAC,SAAS,IAAI,EAAE,CAAC,CAAC,GAAG,CAAC,CAAC,GAAG,EAAE,EAAE,CAAC,CAAC;YAC1C,EAAE,EAAE,UAAU,GAAG,CAAC,kBAAkB,EAAE;YACtC,MAAM,EAAE,QAAiB;YACzB,KAAK,EAAE,GAAG,CAAC,SAAS,IAAI,GAAG,CAAC,kBAAkB;YAC9C,OAAO,EAAE,EAAE;YACX,IAAI,EAAE,GAAG,CAAC,cAAc,CAAC,CAAC,CAAC,GAAG,GAAG,CAAC,cAAc,EAAE,CAAC,CAAC,CAAC,EAAE;YACvD,UAAU,EAAE,eAAe;YAC3B,QAAQ,EAAE,GAAG,GAAG,CAAC,aAAa,IAAI,UAAU,UAAU,GAAG,CAAC,mBAAmB,EAAE,QAAQ,IAAI,SAAS,EAAE;YACtG,GAAG,EAAE,qDAAqD,GAAG,CAAC,kBAAkB,GAAG;SACpF,CAAC,CAAC,CAAC;IACN,CAAC;IAAC,MAAM,CAAC;QACP,OAAO,EAAE,CAAC;IACZ,CAAC;AACH,CAAC"}

package/dist/providers/direct/citeline.d.ts

@@ -0,0 +1,3 @@
+import type { LiteratureResult } from "../types.js";
+export declare function fetchCiteline(query: string, maxResults: number): Promise<LiteratureResult[]>;
+//# sourceMappingURL=citeline.d.ts.map

package/dist/providers/direct/citeline.d.ts.map

@@ -0,0 +1 @@
+{"version":3,"file":"citeline.d.ts","sourceRoot":"","sources":["../../../src/providers/direct/citeline.ts"],"names":[],"mappings":"AAAA,OAAO,KAAK,EAAE,gBAAgB,EAAE,MAAM,aAAa,CAAC;AAsBpD,wBAAsB,aAAa,CACjC,KAAK,EAAE,MAAM,EACb,UAAU,EAAE,MAAM,GACjB,OAAO,CAAC,gBAAgB,EAAE,CAAC,CA4C7B"}

package/dist/providers/direct/citeline.js

@@ -0,0 +1,50 @@
+import { fetchViaProxy, getProxyUrl } from "./proxyClient.js";
+// Citeline TrialTrove API (Informa/Citeline)
+const BASE = "https://api.citeline.com/trialtrove/v1/trials";
+export async function fetchCiteline(query, maxResults) {
+    // Try proxy first (user has Teva access via proxy)
+    if (getProxyUrl()) {
+        const proxyResults = await fetchViaProxy("citeline", query, maxResults);
+        if (proxyResults.length > 0)
+            return proxyResults;
+    }
+    // Fall back to direct API call if key is set
+    const apiKey = process.env.CITELINE_API_KEY;
+    if (!apiKey)
+        return [];
+    try {
+        const url = `${BASE}?q=${encodeURIComponent(query)}&limit=${maxResults}`;
+        const res = await fetch(url, {
+            headers: {
+                Authorization: `Bearer ${apiKey}`,
+                Accept: "application/json",
+            },
+        });
+        if (!res.ok)
+            return [];
+        const data = (await res.json());
+        const trials = data.trials ?? [];
+        return trials.slice(0, maxResults).map((t, i) => ({
+            id: `citeline_${t.trialId ?? i}`,
+            source: "citeline",
+            title: t.title ?? "Untitled trial",
+            authors: t.sponsors ?? [],
+            date: t.startDate ?? "",
+            study_type: "rct",
+            abstract: [
+                `Phase: ${t.phase ?? "N/A"}`,
+                `Status: ${t.status ?? "N/A"}`,
+                `Indication: ${t.indication ?? "N/A"}`,
+                `Therapeutic area: ${t.therapeuticArea ?? "N/A"}`,
+                t.primaryOutcome ? `Primary outcome: ${t.primaryOutcome}` : null,
+            ]
+                .filter(Boolean)
+                .join(" | "),
+            url: `https://citeline.informa.com/trial/${t.trialId ?? ""}`,
+        }));
+    }
+    catch {
+        return [];
+    }
+}
+//# sourceMappingURL=citeline.js.map

package/dist/providers/direct/citeline.js.map

@@ -0,0 +1 @@
+{"version":3,"file":"citeline.js","sourceRoot":"","sources":["../../../src/providers/direct/citeline.ts"],"names":[],"mappings":"AACA,OAAO,EAAE,aAAa,EAAE,WAAW,EAAE,MAAM,kBAAkB,CAAC;AAE9D,6CAA6C;AAC7C,MAAM,IAAI,GAAG,+CAA+C,CAAC;AAkB7D,MAAM,CAAC,KAAK,UAAU,aAAa,CACjC,KAAa,EACb,UAAkB;IAElB,mDAAmD;IACnD,IAAI,WAAW,EAAE,EAAE,CAAC;QAClB,MAAM,YAAY,GAAG,MAAM,aAAa,CAAC,UAAU,EAAE,KAAK,EAAE,UAAU,CAAC,CAAC;QACxE,IAAI,YAAY,CAAC,MAAM,GAAG,CAAC;YAAE,OAAO,YAAY,CAAC;IACnD,CAAC;IAED,6CAA6C;IAC7C,MAAM,MAAM,GAAG,OAAO,CAAC,GAAG,CAAC,gBAAgB,CAAC;IAC5C,IAAI,CAAC,MAAM;QAAE,OAAO,EAAE,CAAC;IAEvB,IAAI,CAAC;QACH,MAAM,GAAG,GAAG,GAAG,IAAI,MAAM,kBAAkB,CAAC,KAAK,CAAC,UAAU,UAAU,EAAE,CAAC;QACzE,MAAM,GAAG,GAAG,MAAM,KAAK,CAAC,GAAG,EAAE;YAC3B,OAAO,EAAE;gBACP,aAAa,EAAE,UAAU,MAAM,EAAE;gBACjC,MAAM,EAAE,kBAAkB;aAC3B;SACF,CAAC,CAAC;QACH,IAAI,CAAC,GAAG,CAAC,EAAE;YAAE,OAAO,EAAE,CAAC;QACvB,MAAM,IAAI,GAAG,CAAC,MAAM,GAAG,CAAC,IAAI,EAAE,CAAqB,CAAC;QACpD,MAAM,MAAM,GAAG,IAAI,CAAC,MAAM,IAAI,EAAE,CAAC;QAEjC,OAAO,MAAM,CAAC,KAAK,CAAC,CAAC,EAAE,UAAU,CAAC,CAAC,GAAG,CAAC,CAAC,CAAC,EAAE,CAAC,EAAE,EAAE,CAAC,CAAC;YAChD,EAAE,EAAE,YAAY,CAAC,CAAC,OAAO,IAAI,CAAC,EAAE;YAChC,MAAM,EAAE,UAAmB;YAC3B,KAAK,EAAE,CAAC,CAAC,KAAK,IAAI,gBAAgB;YAClC,OAAO,EAAE,CAAC,CAAC,QAAQ,IAAI,EAAE;YACzB,IAAI,EAAE,CAAC,CAAC,SAAS,IAAI,EAAE;YACvB,UAAU,EAAE,KAAK;YACjB,QAAQ,EAAE;gBACR,UAAU,CAAC,CAAC,KAAK,IAAI,KAAK,EAAE;gBAC5B,WAAW,CAAC,CAAC,MAAM,IAAI,KAAK,EAAE;gBAC9B,eAAe,CAAC,CAAC,UAAU,IAAI,KAAK,EAAE;gBACtC,qBAAqB,CAAC,CAAC,eAAe,IAAI,KAAK,EAAE;gBACjD,CAAC,CAAC,cAAc,CAAC,CAAC,CAAC,oBAAoB,CAAC,CAAC,cAAc,EAAE,CAAC,CAAC,CAAC,IAAI;aACjE;iBACE,MAAM,CAAC,OAAO,CAAC;iBACf,IAAI,CAAC,KAAK,CAAC;YACd,GAAG,EAAE,sCAAsC,CAAC,CAAC,OAAO,IAAI,EAAE,EAAE;SAC7D,CAAC,CAAC,CAAC;IACN,CAAC;IAAC,MAAM,CAAC;QACP,OAAO,EAAE,CAAC;IACZ,CAAC;AACH,CAAC"}

package/dist/providers/direct/clinicalTrials.d.ts

@@ -0,0 +1,3 @@
+import type { LiteratureResult } from "../types.js";
+export declare function fetchClinicalTrials(query: string, maxResults: number): Promise<LiteratureResult[]>;
+//# sourceMappingURL=clinicalTrials.d.ts.map

package/dist/providers/direct/clinicalTrials.d.ts.map

@@ -0,0 +1 @@
+{"version":3,"file":"clinicalTrials.d.ts","sourceRoot":"","sources":["../../../src/providers/direct/clinicalTrials.ts"],"names":[],"mappings":"AAAA,OAAO,KAAK,EAAE,gBAAgB,EAAE,MAAM,aAAa,CAAC;AAcpD,wBAAsB,mBAAmB,CAAC,KAAK,EAAE,MAAM,EAAE,UAAU,EAAE,MAAM,GAAG,OAAO,CAAC,gBAAgB,EAAE,CAAC,CAyBxG"}

package/dist/providers/direct/clinicalTrials.js

@@ -0,0 +1,29 @@
+const BASE = "https://clinicaltrials.gov/api/v2/studies";
+export async function fetchClinicalTrials(query, maxResults) {
+    try {
+        const url = `${BASE}?query.term=${encodeURIComponent(query)}&pageSize=${maxResults}&format=json`;
+        const res = await fetch(url);
+        if (!res.ok)
+            return [];
+        const data = (await res.json());
+        return (data.studies ?? []).map((study) => {
+            const id = study.protocolSection.identificationModule;
+            const desc = study.protocolSection.descriptionModule;
+            const contacts = study.protocolSection.contactsLocationsModule;
+            return {
+                id: `ct_${id.nctId}`,
+                source: "clinicaltrials",
+                title: id.briefTitle,
+                authors: contacts?.overallOfficials?.map((o) => o.name) ?? [],
+                date: study.protocolSection.statusModule.startDateStruct?.date ?? "",
+                study_type: study.protocolSection.designModule?.studyType?.toLowerCase() ?? "unknown",
+                abstract: desc?.briefSummary ?? "",
+                url: `https://clinicaltrials.gov/study/${id.nctId}`,
+            };
+        });
+    }
+    catch {
+        return [];
+    }
+}
+//# sourceMappingURL=clinicalTrials.js.map

package/dist/providers/direct/clinicalTrials.js.map

@@ -0,0 +1 @@
+{"version":3,"file":"clinicalTrials.js","sourceRoot":"","sources":["../../../src/providers/direct/clinicalTrials.ts"],"names":[],"mappings":"AAEA,MAAM,IAAI,GAAG,2CAA2C,CAAC;AAYzD,MAAM,CAAC,KAAK,UAAU,mBAAmB,CAAC,KAAa,EAAE,UAAkB;IACzE,IAAI,CAAC;QACH,MAAM,GAAG,GAAG,GAAG,IAAI,eAAe,kBAAkB,CAAC,KAAK,CAAC,aAAa,UAAU,cAAc,CAAC;QACjG,MAAM,GAAG,GAAG,MAAM,KAAK,CAAC,GAAG,CAAC,CAAC;QAC7B,IAAI,CAAC,GAAG,CAAC,EAAE;YAAE,OAAO,EAAE,CAAC;QAEvB,MAAM,IAAI,GAAG,CAAC,MAAM,GAAG,CAAC,IAAI,EAAE,CAA2B,CAAC;QAC1D,OAAO,CAAC,IAAI,CAAC,OAAO,IAAI,EAAE,CAAC,CAAC,GAAG,CAAC,CAAC,KAAK,EAAE,EAAE;YACxC,MAAM,EAAE,GAAG,KAAK,CAAC,eAAe,CAAC,oBAAoB,CAAC;YACtD,MAAM,IAAI,GAAG,KAAK,CAAC,eAAe,CAAC,iBAAiB,CAAC;YACrD,MAAM,QAAQ,GAAG,KAAK,CAAC,eAAe,CAAC,uBAAuB,CAAC;YAC/D,OAAO;gBACL,EAAE,EAAE,MAAM,EAAE,CAAC,KAAK,EAAE;gBACpB,MAAM,EAAE,gBAAyB;gBACjC,KAAK,EAAE,EAAE,CAAC,UAAU;gBACpB,OAAO,EAAE,QAAQ,EAAE,gBAAgB,EAAE,GAAG,CAAC,CAAC,CAAC,EAAE,EAAE,CAAC,CAAC,CAAC,IAAI,CAAC,IAAI,EAAE;gBAC7D,IAAI,EAAE,KAAK,CAAC,eAAe,CAAC,YAAY,CAAC,eAAe,EAAE,IAAI,IAAI,EAAE;gBACpE,UAAU,EAAE,KAAK,CAAC,eAAe,CAAC,YAAY,EAAE,SAAS,EAAE,WAAW,EAAE,IAAI,SAAS;gBACrF,QAAQ,EAAE,IAAI,EAAE,YAAY,IAAI,EAAE;gBAClC,GAAG,EAAE,oCAAoC,EAAE,CAAC,KAAK,EAAE;aACpD,CAAC;QACJ,CAAC,CAAC,CAAC;IACL,CAAC;IAAC,MAAM,CAAC;QACP,OAAO,EAAE,CAAC;IACZ,CAAC;AACH,CAAC"}

package/dist/providers/direct/cmsNadac.d.ts

@@ -0,0 +1,3 @@
+import type { LiteratureResult } from "../types.js";
+export declare function fetchCmsNadac(query: string, maxResults: number): Promise<LiteratureResult[]>;
+//# sourceMappingURL=cmsNadac.d.ts.map

package/dist/providers/direct/cmsNadac.d.ts.map

@@ -0,0 +1 @@
+{"version":3,"file":"cmsNadac.d.ts","sourceRoot":"","sources":["../../../src/providers/direct/cmsNadac.ts"],"names":[],"mappings":"AAAA,OAAO,KAAK,EAAE,gBAAgB,EAAE,MAAM,aAAa,CAAC;AAoBpD,wBAAsB,aAAa,CAAC,KAAK,EAAE,MAAM,EAAE,UAAU,EAAE,MAAM,GAAG,OAAO,CAAC,gBAAgB,EAAE,CAAC,CA+BlG"}

package/dist/providers/direct/cmsNadac.js

@@ -0,0 +1,52 @@
+// CMS publishes NADAC data via data.cms.gov. The dataset UUID can be found at:
+// https://data.cms.gov/dataset/nadac
+// We use the data.cms.gov Resources API which returns JSON.
+const BASE = "https://data.cms.gov/data-api/v1/dataset";
+// NADAC dataset UUID (stable since 2022)
+const NADAC_DATASET_ID = "dfa2ab14-06c2-4b99-9f0e-215a6713b5f2";
+export async function fetchCmsNadac(query, maxResults) {
+    try {
+        // The CMS data-api supports filter syntax
+        const url = `${BASE}/${NADAC_DATASET_ID}/data?filter[NDC Description][condition][path]=NDC Description&filter[NDC Description][condition][operator]=CONTAINS&filter[NDC Description][condition][value]=${encodeURIComponent(query.toUpperCase())}&size=${Math.min(maxResults, 100)}`;
+        const res = await fetch(url);
+        if (!res.ok)
+            return getFallback(query, maxResults);
+        const data = (await res.json());
+        if (!Array.isArray(data) || data.length === 0)
+            return getFallback(query, maxResults);
+        return data.slice(0, maxResults).map((row, i) => ({
+            id: `cms_nadac_${row["NDC"] ?? i}`,
+            source: "cms_nadac",
+            title: `${row["NDC Description"] ?? "Unknown drug"} — NADAC $${row["NADAC Per Unit"] ?? "N/A"}/${row["Pricing Unit"] ?? "unit"}`,
+            authors: ["Centers for Medicare & Medicaid Services"],
+            date: row["Effective Date"] ?? "",
+            study_type: "pricing",
+            abstract: [
+                `NDC: ${row["NDC"] ?? "N/A"}`,
+                `NADAC per unit: $${row["NADAC Per Unit"] ?? "N/A"}`,
+                `Pricing unit: ${row["Pricing Unit"] ?? "N/A"}`,
+                `Classification: ${row["Classification for Rate Setting"] ?? "N/A"}`,
+                `Pharmacy type: ${row["Pharmacy Type Indicator"] ?? "N/A"}`,
+                `OTC: ${row["OTC"] ?? "N"}`,
+                `Effective: ${row["Effective Date"] ?? ""}`,
+            ].join(" | "),
+            url: `https://data.cms.gov/dataset/dfa2ab14-06c2-4b99-9f0e-215a6713b5f2/data?filter[NDC]=${row["NDC"] ?? ""}`,
+        }));
+    }
+    catch {
+        return getFallback(query, maxResults);
+    }
+}
+function getFallback(query, maxResults) {
+    return [{
+            id: "cms_nadac_search",
+            source: "cms_nadac",
+            title: `CMS NADAC Search: ${query}`,
+            authors: ["Centers for Medicare & Medicaid Services"],
+            date: new Date().getFullYear().toString(),
+            study_type: "pricing",
+            abstract: `Search the CMS National Average Drug Acquisition Cost (NADAC) dataset for "${query}". NADAC provides weekly updated average acquisition costs for all covered outpatient drugs, based on a monthly survey of retail community pharmacies. Used as a reference benchmark for Medicaid pharmacy reimbursement.`,
+            url: `https://data.cms.gov/dataset/nadac?query=${encodeURIComponent(query)}`,
+        }].slice(0, maxResults);
+}
+//# sourceMappingURL=cmsNadac.js.map

package/dist/providers/direct/cmsNadac.js.map

@@ -0,0 +1 @@
+{"version":3,"file":"cmsNadac.js","sourceRoot":"","sources":["../../../src/providers/direct/cmsNadac.ts"],"names":[],"mappings":"AAEA,+EAA+E;AAC/E,qCAAqC;AACrC,4DAA4D;AAC5D,MAAM,IAAI,GAAG,0CAA0C,CAAC;AACxD,yCAAyC;AACzC,MAAM,gBAAgB,GAAG,sCAAsC,CAAC;AAahE,MAAM,CAAC,KAAK,UAAU,aAAa,CAAC,KAAa,EAAE,UAAkB;IACnE,IAAI,CAAC;QACH,0CAA0C;QAC1C,MAAM,GAAG,GAAG,GAAG,IAAI,IAAI,gBAAgB,kKAAkK,kBAAkB,CAAC,KAAK,CAAC,WAAW,EAAE,CAAC,SAAS,IAAI,CAAC,GAAG,CAAC,UAAU,EAAE,GAAG,CAAC,EAAE,CAAC;QACrR,MAAM,GAAG,GAAG,MAAM,KAAK,CAAC,GAAG,CAAC,CAAC;QAC7B,IAAI,CAAC,GAAG,CAAC,EAAE;YAAE,OAAO,WAAW,CAAC,KAAK,EAAE,UAAU,CAAC,CAAC;QAEnD,MAAM,IAAI,GAAG,CAAC,MAAM,GAAG,CAAC,IAAI,EAAE,CAAe,CAAC;QAC9C,IAAI,CAAC,KAAK,CAAC,OAAO,CAAC,IAAI,CAAC,IAAI,IAAI,CAAC,MAAM,KAAK,CAAC;YAAE,OAAO,WAAW,CAAC,KAAK,EAAE,UAAU,CAAC,CAAC;QAErF,OAAO,IAAI,CAAC,KAAK,CAAC,CAAC,EAAE,UAAU,CAAC,CAAC,GAAG,CAAC,CAAC,GAAG,EAAE,CAAC,EAAE,EAAE,CAAC,CAAC;YAChD,EAAE,EAAE,aAAa,GAAG,CAAC,KAAK,CAAC,IAAI,CAAC,EAAE;YAClC,MAAM,EAAE,WAAoB;YAC5B,KAAK,EAAE,GAAG,GAAG,CAAC,iBAAiB,CAAC,IAAI,cAAc,aAAa,GAAG,CAAC,gBAAgB,CAAC,IAAI,KAAK,IAAI,GAAG,CAAC,cAAc,CAAC,IAAI,MAAM,EAAE;YAChI,OAAO,EAAE,CAAC,0CAA0C,CAAC;YACrD,IAAI,EAAE,GAAG,CAAC,gBAAgB,CAAC,IAAI,EAAE;YACjC,UAAU,EAAE,SAAS;YACrB,QAAQ,EAAE;gBACR,QAAQ,GAAG,CAAC,KAAK,CAAC,IAAI,KAAK,EAAE;gBAC7B,oBAAoB,GAAG,CAAC,gBAAgB,CAAC,IAAI,KAAK,EAAE;gBACpD,iBAAiB,GAAG,CAAC,cAAc,CAAC,IAAI,KAAK,EAAE;gBAC/C,mBAAmB,GAAG,CAAC,iCAAiC,CAAC,IAAI,KAAK,EAAE;gBACpE,kBAAkB,GAAG,CAAC,yBAAyB,CAAC,IAAI,KAAK,EAAE;gBAC3D,QAAQ,GAAG,CAAC,KAAK,CAAC,IAAI,GAAG,EAAE;gBAC3B,cAAc,GAAG,CAAC,gBAAgB,CAAC,IAAI,EAAE,EAAE;aAC5C,CAAC,IAAI,CAAC,KAAK,CAAC;YACb,GAAG,EAAE,sFAAsF,GAAG,CAAC,KAAK,CAAC,IAAI,EAAE,EAAE;SAC9G,CAAC,CAAC,CAAC;IACN,CAAC;IAAC,MAAM,CAAC;QACP,OAAO,WAAW,CAAC,KAAK,EAAE,UAAU,CAAC,CAAC;IACxC,CAAC;AACH,CAAC;AAED,SAAS,WAAW,CAAC,KAAa,EAAE,UAAkB;IACpD,OAAO,CAAC;YACN,EAAE,EAAE,kBAAkB;YACtB,MAAM,EAAE,WAAoB;YAC5B,KAAK,EAAE,qBAAqB,KAAK,EAAE;YACnC,OAAO,EAAE,CAAC,0CAA0C,CAAC;YACrD,IAAI,EAAE,IAAI,IAAI,EAAE,CAAC,WAAW,EAAE,CAAC,QAAQ,EAAE;YACzC,UAAU,EAAE,SAAS;YACrB,QAAQ,EAAE,8EAA8E,KAAK,2NAA2N;YACxT,GAAG,EAAE,4CAA4C,kBAAkB,CAAC,KAAK,CAAC,EAAE;SAC7E,CAAC,CAAC,KAAK,CAAC,CAAC,EAAE,UAAU,CAAC,CAAC;AAC1B,CAAC"}

package/dist/providers/direct/cochrane.d.ts

@@ -0,0 +1,3 @@
+import type { LiteratureResult } from "../types.js";
+export declare function fetchCochrane(query: string, maxResults: number): Promise<LiteratureResult[]>;
+//# sourceMappingURL=cochrane.d.ts.map

package/dist/providers/direct/cochrane.d.ts.map

@@ -0,0 +1 @@
+{"version":3,"file":"cochrane.d.ts","sourceRoot":"","sources":["../../../src/providers/direct/cochrane.ts"],"names":[],"mappings":"AAAA,OAAO,KAAK,EAAE,gBAAgB,EAAE,MAAM,aAAa,CAAC;AAmBpD,wBAAsB,aAAa,CACjC,KAAK,EAAE,MAAM,EACb,UAAU,EAAE,MAAM,GACjB,OAAO,CAAC,gBAAgB,EAAE,CAAC,CAwC7B"}

package/dist/providers/direct/cochrane.js

@@ -0,0 +1,46 @@
+import { fetchViaProxy, getProxyUrl } from "./proxyClient.js";
+// Wiley Online Library API — Cochrane Library is published by Wiley
+const BASE = "https://api.wiley.com/onlinelibrary/tdm/v1/articles";
+export async function fetchCochrane(query, maxResults) {
+    // Try proxy first (user has Teva access via proxy)
+    if (getProxyUrl()) {
+        const proxyResults = await fetchViaProxy("cochrane", query, maxResults);
+        if (proxyResults.length > 0)
+            return proxyResults;
+    }
+    // Fall back to direct API call if key is set
+    const apiKey = process.env.COCHRANE_API_KEY;
+    if (!apiKey)
+        return [];
+    try {
+        const url = `${BASE}?q=${encodeURIComponent(query)}&rows=${maxResults}&filter=publication:cochrane`;
+        const res = await fetch(url, {
+            headers: {
+                "Wiley-TDM-Client-Token": apiKey,
+                Accept: "application/json",
+            },
+        });
+        if (!res.ok)
+            return [];
+        const data = (await res.json());
+        const items = data.items ?? [];
+        return items.slice(0, maxResults).map((item, i) => ({
+            id: `cochrane_${item.doi ?? i}`,
+            source: "cochrane",
+            title: item.title ?? "Untitled Cochrane Review",
+            authors: item.authors ?? [],
+            date: item.publicationDate ?? "",
+            study_type: item.reviewType?.toLowerCase().includes("meta")
+                ? "meta_analysis"
+                : "review",
+            abstract: item.abstract ?? "",
+            url: item.doi
+                ? `https://doi.org/${item.doi}`
+                : "https://www.cochranelibrary.com/",
+        }));
+    }
+    catch {
+        return [];
+    }
+}
+//# sourceMappingURL=cochrane.js.map

package/dist/providers/direct/cochrane.js.map

@@ -0,0 +1 @@
+{"version":3,"file":"cochrane.js","sourceRoot":"","sources":["../../../src/providers/direct/cochrane.ts"],"names":[],"mappings":"AACA,OAAO,EAAE,aAAa,EAAE,WAAW,EAAE,MAAM,kBAAkB,CAAC;AAE9D,oEAAoE;AACpE,MAAM,IAAI,GAAG,qDAAqD,CAAC;AAenE,MAAM,CAAC,KAAK,UAAU,aAAa,CACjC,KAAa,EACb,UAAkB;IAElB,mDAAmD;IACnD,IAAI,WAAW,EAAE,EAAE,CAAC;QAClB,MAAM,YAAY,GAAG,MAAM,aAAa,CAAC,UAAU,EAAE,KAAK,EAAE,UAAU,CAAC,CAAC;QACxE,IAAI,YAAY,CAAC,MAAM,GAAG,CAAC;YAAE,OAAO,YAAY,CAAC;IACnD,CAAC;IAED,6CAA6C;IAC7C,MAAM,MAAM,GAAG,OAAO,CAAC,GAAG,CAAC,gBAAgB,CAAC;IAC5C,IAAI,CAAC,MAAM;QAAE,OAAO,EAAE,CAAC;IAEvB,IAAI,CAAC;QACH,MAAM,GAAG,GAAG,GAAG,IAAI,MAAM,kBAAkB,CAAC,KAAK,CAAC,SAAS,UAAU,8BAA8B,CAAC;QACpG,MAAM,GAAG,GAAG,MAAM,KAAK,CAAC,GAAG,EAAE;YAC3B,OAAO,EAAE;gBACP,wBAAwB,EAAE,MAAM;gBAChC,MAAM,EAAE,kBAAkB;aAC3B;SACF,CAAC,CAAC;QACH,IAAI,CAAC,GAAG,CAAC,EAAE;YAAE,OAAO,EAAE,CAAC;QACvB,MAAM,IAAI,GAAG,CAAC,MAAM,GAAG,CAAC,IAAI,EAAE,CAAqB,CAAC;QACpD,MAAM,KAAK,GAAG,IAAI,CAAC,KAAK,IAAI,EAAE,CAAC;QAE/B,OAAO,KAAK,CAAC,KAAK,CAAC,CAAC,EAAE,UAAU,CAAC,CAAC,GAAG,CAAC,CAAC,IAAI,EAAE,CAAC,EAAE,EAAE,CAAC,CAAC;YAClD,EAAE,EAAE,YAAY,IAAI,CAAC,GAAG,IAAI,CAAC,EAAE;YAC/B,MAAM,EAAE,UAAmB;YAC3B,KAAK,EAAE,IAAI,CAAC,KAAK,IAAI,0BAA0B;YAC/C,OAAO,EAAE,IAAI,CAAC,OAAO,IAAI,EAAE;YAC3B,IAAI,EAAE,IAAI,CAAC,eAAe,IAAI,EAAE;YAChC,UAAU,EAAE,IAAI,CAAC,UAAU,EAAE,WAAW,EAAE,CAAC,QAAQ,CAAC,MAAM,CAAC;gBACzD,CAAC,CAAC,eAAe;gBACjB,CAAC,CAAC,QAAQ;YACZ,QAAQ,EAAE,IAAI,CAAC,QAAQ,IAAI,EAAE;YAC7B,GAAG,EAAE,IAAI,CAAC,GAAG;gBACX,CAAC,CAAC,mBAAmB,IAAI,CAAC,GAAG,EAAE;gBAC/B,CAAC,CAAC,kCAAkC;SACvC,CAAC,CAAC,CAAC;IACN,CAAC;IAAC,MAAM,CAAC;QACP,OAAO,EAAE,CAAC;IACZ,CAAC;AACH,CAAC"}

package/dist/providers/direct/conitec.d.ts

@@ -0,0 +1,3 @@
+import type { LiteratureResult } from "../types.js";
+export declare function fetchConitec(query: string, maxResults: number): Promise<LiteratureResult[]>;
+//# sourceMappingURL=conitec.d.ts.map

package/dist/providers/direct/conitec.d.ts.map

@@ -0,0 +1 @@
+{"version":3,"file":"conitec.d.ts","sourceRoot":"","sources":["../../../src/providers/direct/conitec.ts"],"names":[],"mappings":"AAAA,OAAO,KAAK,EAAE,gBAAgB,EAAE,MAAM,aAAa,CAAC;AAEpD,wBAAsB,YAAY,CAAC,KAAK,EAAE,MAAM,EAAE,UAAU,EAAE,MAAM,GAAG,OAAO,CAAC,gBAAgB,EAAE,CAAC,CAwBjG"}

package/dist/providers/direct/conitec.js

@@ -0,0 +1,25 @@
+export async function fetchConitec(query, maxResults) {
+    const entries = [
+        {
+            title: `CONITEC Reports: ${query}`,
+            abstract: `CONITEC (Comissão Nacional de Incorporação de Tecnologias no SUS) is Brazil's HTA agency. Published reports include cost-effectiveness analyses, budget impact analyses, and incorporation recommendations for SUS. Search "${query}" for relevant Brazilian HTA precedents. Decisions published in Portuguese.`,
+            url: `https://www.gov.br/conitec/pt-br/assuntos/tecnologias-avaliadas/busca?search_api_fulltext=${encodeURIComponent(query)}`,
+        },
+        {
+            title: `CONITEC Methodology Guidelines`,
+            abstract: `CONITEC's methodology guidelines for economic evaluation of health technologies in Brazil. Covers cost-effectiveness analysis, budget impact analysis, and recommendations structure for SUS submissions.`,
+            url: "https://www.gov.br/conitec/pt-br/assuntos/diretrizes-metodologicas",
+        },
+    ];
+    return entries.slice(0, maxResults).map((e, i) => ({
+        id: `conitec_${i}`,
+        source: "conitec",
+        title: e.title,
+        authors: ["CONITEC — Brazilian Ministry of Health"],
+        date: new Date().getFullYear().toString(),
+        study_type: "hta_report",
+        abstract: e.abstract,
+        url: e.url,
+    }));
+}
+//# sourceMappingURL=conitec.js.map

package/dist/providers/direct/conitec.js.map

@@ -0,0 +1 @@
+{"version":3,"file":"conitec.js","sourceRoot":"","sources":["../../../src/providers/direct/conitec.ts"],"names":[],"mappings":"AAEA,MAAM,CAAC,KAAK,UAAU,YAAY,CAAC,KAAa,EAAE,UAAkB;IAClE,MAAM,OAAO,GAAG;QACd;YACE,KAAK,EAAE,oBAAoB,KAAK,EAAE;YAClC,QAAQ,EAAE,+NAA+N,KAAK,6EAA6E;YAC3T,GAAG,EAAE,6FAA6F,kBAAkB,CAAC,KAAK,CAAC,EAAE;SAC9H;QACD;YACE,KAAK,EAAE,gCAAgC;YACvC,QAAQ,EAAE,2MAA2M;YACrN,GAAG,EAAE,oEAAoE;SAC1E;KACF,CAAC;IAEF,OAAO,OAAO,CAAC,KAAK,CAAC,CAAC,EAAE,UAAU,CAAC,CAAC,GAAG,CAAC,CAAC,CAAC,EAAE,CAAC,EAAE,EAAE,CAAC,CAAC;QACjD,EAAE,EAAE,WAAW,CAAC,EAAE;QAClB,MAAM,EAAE,SAAkB;QAC1B,KAAK,EAAE,CAAC,CAAC,KAAK;QACd,OAAO,EAAE,CAAC,wCAAwC,CAAC;QACnD,IAAI,EAAE,IAAI,IAAI,EAAE,CAAC,WAAW,EAAE,CAAC,QAAQ,EAAE;QACzC,UAAU,EAAE,YAAY;QACxB,QAAQ,EAAE,CAAC,CAAC,QAAQ;QACpB,GAAG,EAAE,CAAC,CAAC,GAAG;KACX,CAAC,CAAC,CAAC;AACN,CAAC"}

package/dist/providers/direct/cortellis.d.ts

@@ -0,0 +1,3 @@
+import type { LiteratureResult } from "../types.js";
+export declare function fetchCortellis(query: string, maxResults: number): Promise<LiteratureResult[]>;
+//# sourceMappingURL=cortellis.d.ts.map

package/dist/providers/direct/cortellis.d.ts.map

@@ -0,0 +1 @@
+{"version":3,"file":"cortellis.d.ts","sourceRoot":"","sources":["../../../src/providers/direct/cortellis.ts"],"names":[],"mappings":"AAAA,OAAO,KAAK,EAAE,gBAAgB,EAAE,MAAM,aAAa,CAAC;AAqBpD,wBAAsB,cAAc,CAClC,KAAK,EAAE,MAAM,EACb,UAAU,EAAE,MAAM,GACjB,OAAO,CAAC,gBAAgB,EAAE,CAAC,CA8C7B"}

package/dist/providers/direct/cortellis.js

@@ -0,0 +1,52 @@
+import { fetchViaProxy, getProxyUrl } from "./proxyClient.js";
+// Clarivate Cortellis Competitive Intelligence API
+const BASE = "https://api.cortellis.com/v2/search/ci";
+export async function fetchCortellis(query, maxResults) {
+    // Try proxy first (user has Teva access via proxy)
+    if (getProxyUrl()) {
+        const proxyResults = await fetchViaProxy("cortellis", query, maxResults);
+        if (proxyResults.length > 0)
+            return proxyResults;
+    }
+    // Fall back to direct API call if key is set
+    const apiKey = process.env.CORTELLIS_API_KEY;
+    if (!apiKey)
+        return [];
+    try {
+        const url = `${BASE}?q=${encodeURIComponent(query)}&limit=${maxResults}`;
+        const res = await fetch(url, {
+            headers: {
+                Authorization: `Bearer ${apiKey}`,
+                Accept: "application/json",
+            },
+        });
+        if (!res.ok)
+            return [];
+        const data = (await res.json());
+        const drugs = data.results ?? [];
+        return drugs.slice(0, maxResults).map((d, i) => ({
+            id: `cortellis_${d.id ?? i}`,
+            source: "cortellis",
+            title: `${d.name ?? "Unknown"} (${d.phase ?? "N/A"}) — ${d.sponsor ?? "Unknown sponsor"}`,
+            authors: [d.sponsor ?? "Clarivate"],
+            date: d.updatedDate ?? "",
+            study_type: "pipeline",
+            abstract: [
+                `Phase: ${d.phase ?? "N/A"}`,
+                `Sponsor: ${d.sponsor ?? "N/A"}`,
+                `Indications: ${(d.indications ?? []).join(", ") || "N/A"}`,
+                `MoA: ${d.mechanismOfAction ?? "N/A"}`,
+                d.consensusForecast
+                    ? `Consensus forecast: ${d.consensusForecast}`
+                    : null,
+            ]
+                .filter(Boolean)
+                .join(" | "),
+            url: `https://www.cortellis.com/`,
+        }));
+    }
+    catch {
+        return [];
+    }
+}
+//# sourceMappingURL=cortellis.js.map

package/dist/providers/direct/cortellis.js.map

@@ -0,0 +1 @@
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package/dist/providers/direct/datasus.d.ts

@@ -0,0 +1,3 @@
+import type { LiteratureResult } from "../types.js";
+export declare function fetchDatasus(query: string, maxResults: number): Promise<LiteratureResult[]>;
+//# sourceMappingURL=datasus.d.ts.map

package/dist/providers/direct/datasus.d.ts.map

@@ -0,0 +1 @@
+{"version":3,"file":"datasus.d.ts","sourceRoot":"","sources":["../../../src/providers/direct/datasus.ts"],"names":[],"mappings":"AAAA,OAAO,KAAK,EAAE,gBAAgB,EAAE,MAAM,aAAa,CAAC;AAEpD,wBAAsB,YAAY,CAAC,KAAK,EAAE,MAAM,EAAE,UAAU,EAAE,MAAM,GAAG,OAAO,CAAC,gBAAgB,EAAE,CAAC,CA6BjG"}

package/dist/providers/direct/datasus.js

@@ -0,0 +1,30 @@
+export async function fetchDatasus(query, maxResults) {
+    const entries = [
+        {
+            title: `DATASUS TabNet: ${query}`,
+            abstract: `Brazilian Unified Health System (SUS) database. TabNet provides web-based access to aggregated SUS data: hospitalizations (SIH/SUS), outpatient procedures (SIA/SUS), mortality (SIM), births (SINASC), notifiable diseases (SINAN), and population estimates. Essential for Brazilian HEOR studies and CONITEC submissions. Search "${query}" across all modules.`,
+            url: `http://tabnet.datasus.gov.br/cgi/tabcgi.exe?sih/cnv/qiuf.def`,
+        },
+        {
+            title: `SIH/SUS Hospital Information System — ${query}`,
+            abstract: `SIH/SUS (Sistema de Informações Hospitalares) contains all SUS-funded hospital admissions in Brazil with ICD-10 diagnoses, procedures, length of stay, and reimbursement. ~12M admissions/year. Primary source for Brazilian hospitalization cost data.`,
+            url: `http://www2.datasus.gov.br/DATASUS/index.php?area=0202`,
+        },
+        {
+            title: `SIA/SUS Ambulatory Information System`,
+            abstract: `SIA/SUS covers outpatient procedures funded by SUS: consultations, exams, specialty appointments, chemotherapy, radiotherapy, dialysis. Used for outpatient cost modeling in Brazilian HEOR submissions.`,
+            url: `http://www2.datasus.gov.br/DATASUS/index.php?area=0201`,
+        },
+    ];
+    return entries.slice(0, maxResults).map((e, i) => ({
+        id: `datasus_${i}`,
+        source: "datasus",
+        title: e.title,
+        authors: ["Brazilian Ministry of Health — DATASUS"],
+        date: new Date().getFullYear().toString(),
+        study_type: "registry",
+        abstract: e.abstract,
+        url: e.url,
+    }));
+}
+//# sourceMappingURL=datasus.js.map

package/dist/providers/direct/datasus.js.map

@@ -0,0 +1 @@
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package/dist/providers/direct/embase.d.ts

@@ -0,0 +1,3 @@
+import type { LiteratureResult } from "../types.js";
+export declare function fetchEmbase(query: string, maxResults: number): Promise<LiteratureResult[]>;
+//# sourceMappingURL=embase.d.ts.map

package/dist/providers/direct/embase.d.ts.map

@@ -0,0 +1 @@
+{"version":3,"file":"embase.d.ts","sourceRoot":"","sources":["../../../src/providers/direct/embase.ts"],"names":[],"mappings":"AAAA,OAAO,KAAK,EAAE,gBAAgB,EAAE,MAAM,aAAa,CAAC;AAsBpD,wBAAsB,WAAW,CAC/B,KAAK,EAAE,MAAM,EACb,UAAU,EAAE,MAAM,GACjB,OAAO,CAAC,gBAAgB,EAAE,CAAC,CAuC7B"}

package/dist/providers/direct/embase.js

@@ -0,0 +1,54 @@
+const BASE = "https://api.elsevier.com/content/search/embase";
+export async function fetchEmbase(query, maxResults) {
+    const apiKey = process.env.ELSEVIER_API_KEY;
+    if (!apiKey)
+        return [];
+    try {
+        const url = `${BASE}?query=${encodeURIComponent(query)}&count=${maxResults}&field=title,creator,coverDate,description,url,doi,pii,subtypeDescription`;
+        const res = await fetch(url, {
+            headers: {
+                "X-ELS-APIKey": apiKey,
+                "Accept": "application/json",
+            },
+        });
+        if (!res.ok)
+            return [];
+        const data = (await res.json());
+        const entries = data["search-results"]?.entry ?? [];
+        return entries
+            .filter((e) => e["dc:title"])
+            .map((e, i) => {
+            const doi = e["prism:doi"];
+            const pii = e["pii"];
+            const id = doi ?? pii ?? `embase_${i}`;
+            return {
+                id: `embase_${id}`,
+                source: "embase",
+                title: e["dc:title"] ?? "",
+                authors: e["dc:creator"] ? [e["dc:creator"]] : [],
+                date: e["prism:coverDate"] ?? "",
+                study_type: mapSubtype(e["subtypeDescription"]),
+                abstract: e["dc:description"] ?? "",
+                url: doi
+                    ? `https://doi.org/${doi}`
+                    : (e["prism:url"] ?? ""),
+            };
+        });
+    }
+    catch {
+        return [];
+    }
+}
+function mapSubtype(subtype) {
+    if (!subtype)
+        return "unknown";
+    const s = subtype.toLowerCase();
+    if (s.includes("review") || s.includes("meta"))
+        return "review";
+    if (s.includes("randomized") || s.includes("controlled"))
+        return "rct";
+    if (s.includes("observational") || s.includes("cohort"))
+        return "observational";
+    return "unknown";
+}
+//# sourceMappingURL=embase.js.map

package/dist/providers/direct/embase.js.map

@@ -0,0 +1 @@
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package/dist/providers/direct/fonasa.d.ts

@@ -0,0 +1,3 @@
+import type { LiteratureResult } from "../types.js";
+export declare function fetchFonasa(query: string, maxResults: number): Promise<LiteratureResult[]>;
+//# sourceMappingURL=fonasa.d.ts.map

package/dist/providers/direct/fonasa.d.ts.map

@@ -0,0 +1 @@
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