@sjcrh/proteinpaint-client 2.222.0 → 2.224.0

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (868) hide show
  1. package/dist/2dmaf-AHG6N6GX.js +1362 -0
  2. package/dist/AggMatrixInput-A4EATVXG.js +402 -0
  3. package/dist/AggregateMatrix-3D36XP7Q.js +37 -0
  4. package/dist/AppHeader-LBFNK6BI.js +826 -0
  5. package/dist/BoxPlot-JNISSUMV.js +1229 -0
  6. package/dist/CorrelationVolcano-BXXFXVHQ.js +613 -0
  7. package/dist/Cuminc-PYG3TJSE.js +1217 -0
  8. package/dist/DE-QGNB5JKB.js +85 -0
  9. package/dist/DEinput-YVXCVTCX.js +479 -0
  10. package/dist/DM-D37YHRJL.js +86 -0
  11. package/dist/DifferentialAnalysis-TFWK7UE7.js +236 -0
  12. package/dist/Disco-PXBROYMP.js +3384 -0
  13. package/dist/Disco.UI-XERJSEDE.js +239 -0
  14. package/dist/DmrPlot-G3QAPQ5I.js +361 -0
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  17. package/dist/GeneExpInput-EYNET6LR.js +38 -0
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  37. package/dist/ProteomeInput-4M2SXSJG.js +610 -0
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  143. package/dist/condition-ZDF5SRLZ.js +323 -0
  144. package/dist/controls-Z4URI2HB.js +30 -0
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  150. package/dist/dictionary-S4MSWVZV.js +109 -0
  151. package/dist/dnaMethylation-QMKO3DXK.js +29 -0
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  153. package/dist/dofetch-4P5F5ZGU.js +49 -0
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  163. package/dist/geneORA-NWJCROO7.js +269 -0
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  216. package/dist/proteinView-ZHNMVSLF.js +1346 -0
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  807. /package/dist/{selectGenomeWithTklst-LGBKEN3T.js.map → selectGenomeWithTklst-YQMYWVXF.js.map} +0 -0
  808. /package/dist/{singleCellCellType-ACQACM6W.js.map → singleCellCellType-AJEAQL4Y.js.map} +0 -0
  809. /package/dist/{singleCellCellType.unit.spec-WLGTJKOM.js.map → singleCellCellType.unit.spec-7YCO4VV7.js.map} +0 -0
  810. /package/dist/{singleCellGeneExpression-M4RPITJW.js.map → singleCellGeneExpression-LPDACSPJ.js.map} +0 -0
  811. /package/dist/{singleCellGeneExpression.unit.spec-N3VD6PUW.js.map → singleCellGeneExpression.unit.spec-JZHG5OAH.js.map} +0 -0
  812. /package/dist/{singleCellNumericValue-W6F44FJN.js.map → singleCellNumericValue-SDUSPCBR.js.map} +0 -0
  813. /package/dist/{singleCellNumericValue.unit.spec-JZNMY77I.js.map → singleCellNumericValue.unit.spec-VQSNCIJC.js.map} +0 -0
  814. /package/dist/{singleCellPlot-CCG2KSCO.js.map → singleCellPlot-5AAE5QGD.js.map} +0 -0
  815. /package/dist/{singlecell-I6H3Z7FT.js.map → singlecell-7XO5TLVF.js.map} +0 -0
  816. /package/dist/{singlecell-32P47E4I.js.map → singlecell-MUI27JKF.js.map} +0 -0
  817. /package/dist/{snp-7X2BXRQP.js.map → snp-2QX25UKB.js.map} +0 -0
  818. /package/dist/{snp.unit.spec-BJGWNSVR.js.map → snp.unit.spec-6B7ZUD7Q.js.map} +0 -0
  819. /package/dist/{snplocus-UOVS2GD6.js.map → snplocus-GMWNSSHV.js.map} +0 -0
  820. /package/dist/{snplst-JFVP4NG2.js.map → snplst-6NAHQAXI.js.map} +0 -0
  821. /package/dist/{spliceevent.a53ss.diagram-ETXJX57W.js.map → spliceevent.a53ss.diagram-WUHKYRWG.js.map} +0 -0
  822. /package/dist/{spliceevent.exonskip.diagram-C4JCEOXQ.js.map → spliceevent.exonskip.diagram-KAFGBL2I.js.map} +0 -0
  823. /package/dist/{spliceevent.noeventdiagram-4DD3Z4OM.js.map → spliceevent.noeventdiagram-SUBU5BLZ.js.map} +0 -0
  824. /package/dist/{ssGSEA-GOZOYROM.js.map → ssGSEA-V4W3E6MF.js.map} +0 -0
  825. /package/dist/{ssGSEA.unit.spec-J4DPFU4D.js.map → ssGSEA.unit.spec-DYMT2CCB.js.map} +0 -0
  826. /package/dist/{stattable-ICUZQHUF.js.map → stattable-DJCYOA6Y.js.map} +0 -0
  827. /package/dist/{studyCatalog-PCFXVOI3.js.map → studyCatalog-TOGQ24WQ.js.map} +0 -0
  828. /package/dist/{summarizeCnvGeneexp-DK6HNUFE.js.map → summarizeCnvGeneexp-6Z3VVSMQ.js.map} +0 -0
  829. /package/dist/{summarizeGeneexpSurvival-JLCR2VIX.js.map → summarizeGeneexpSurvival-REIPWAEJ.js.map} +0 -0
  830. /package/dist/{summarizeMutationCnv-CFAKT6IP.js.map → summarizeMutationCnv-OJNIJR55.js.map} +0 -0
  831. /package/dist/{summarizeMutationDiagnosis-5HMVSYMI.js.map → summarizeMutationDiagnosis-PVOTM3DF.js.map} +0 -0
  832. /package/dist/{summarizeMutationSurvival-GP2OQMUS.js.map → summarizeMutationSurvival-X7TV3EKS.js.map} +0 -0
  833. /package/dist/{summary-6K553VNS.js.map → summary-RNNIEEHQ.js.map} +0 -0
  834. /package/dist/{summary.integration.spec-MXERZOVY.js.map → summary.integration.spec-PEICP7YJ.js.map} +0 -0
  835. /package/dist/{summaryInput-V2G6HFJS.js.map → summaryInput-53MQOUXV.js.map} +0 -0
  836. /package/dist/{sunburst-6GKVNIRF.js.map → sunburst-MYKDYBVD.js.map} +0 -0
  837. /package/dist/{sunburst-YOVKC5G2.js.map → sunburst-OMNCQM26.js.map} +0 -0
  838. /package/dist/{survival-GHTV2ZPX.js.map → survival-3IECSQKM.js.map} +0 -0
  839. /package/dist/{survival-KF2QUWSM.js.map → survival-TQZXLQMK.js.map} +0 -0
  840. /package/dist/{survival.integration.spec-GVSQL4VB.js.map → survival.integration.spec-IMLRYIX2.js.map} +0 -0
  841. /package/dist/{svgraph-WN3JLEOC.js.map → svgraph-YE4MTHLA.js.map} +0 -0
  842. /package/dist/{svmr-ZZKBQFQK.js.map → svmr-KY3V2L4L.js.map} +0 -0
  843. /package/dist/{swimmer-XHORJEVI.js.map → swimmer-HO32NUCE.js.map} +0 -0
  844. /package/dist/{table-XQCTNHSZ.js.map → table-6VZK2B2G.js.map} +0 -0
  845. /package/dist/{termCollection-DXZQT7YT.js.map → termCollection-AMV35ML5.js.map} +0 -0
  846. /package/dist/{termCollection-HRM2NHLA.js.map → termCollection-ETWJLZJT.js.map} +0 -0
  847. /package/dist/{termCollection.unit.spec-BGULSLH6.js.map → termCollection.unit.spec-QHKLFPWO.js.map} +0 -0
  848. /package/dist/{termCollectionFractionSelection-TPNNP2ER.js.map → termCollectionFractionSelection-ZNMCUSN4.js.map} +0 -0
  849. /package/dist/{termCollectionFractionSelection.unit.spec-VONXAGZH.js.map → termCollectionFractionSelection.unit.spec-PO4BHCMC.js.map} +0 -0
  850. /package/dist/{tk-KPD6HTHR.js.map → tk-7OE7QMYG.js.map} +0 -0
  851. /package/dist/{tk-RCTQPQH7.js.map → tk-R6IBTAYE.js.map} +0 -0
  852. /package/dist/{tp.ui-MVNQLMAD.js.map → tp.ui-BGSBCIR7.js.map} +0 -0
  853. /package/dist/{tvs.categorical-4TKKU6HO.js.map → tvs.categorical-RTSI5L6T.js.map} +0 -0
  854. /package/dist/{tvs.condition-SARY3O5Y.js.map → tvs.condition-VBDUN33K.js.map} +0 -0
  855. /package/dist/{tvs.dt-XJ2MW2AP.js.map → tvs.dt-NP6556P7.js.map} +0 -0
  856. /package/dist/{tvs.dtcnv.categorical-H7FKTXH4.js.map → tvs.dtcnv.categorical-RERJRI5J.js.map} +0 -0
  857. /package/dist/{tvs.dtcnv.continuous-JQ62ZHER.js.map → tvs.dtcnv.continuous-UEVWYT3H.js.map} +0 -0
  858. /package/dist/{tvs.dtfusion-GC3DZ2BO.js.map → tvs.dtfusion-CRJ77JUK.js.map} +0 -0
  859. /package/dist/{tvs.dtitd-3SHGIDIB.js.map → tvs.dtitd-ZOCNVICE.js.map} +0 -0
  860. /package/dist/{tvs.dtsnvindel-BEDWZ4A2.js.map → tvs.dtsnvindel-LFWG54AQ.js.map} +0 -0
  861. /package/dist/{tvs.dtsv-HRIMULVD.js.map → tvs.dtsv-SNIZC3C6.js.map} +0 -0
  862. /package/dist/{tvs.multivalue-5VC7BLSZ.js.map → tvs.multivalue-UJS4743S.js.map} +0 -0
  863. /package/dist/{tvs.numeric-TGEC7G6A.js.map → tvs.numeric-KKMUTKSJ.js.map} +0 -0
  864. /package/dist/{tvs.samplelst-Q6EYAUQZ.js.map → tvs.samplelst-AW3IY3CB.js.map} +0 -0
  865. /package/dist/{tvs.survival-NJ3DTZIG.js.map → tvs.survival-LH2Z3WTM.js.map} +0 -0
  866. /package/dist/{tvs.termCollection-TVVLPSTG.js.map → tvs.termCollection-OQNMYVX5.js.map} +0 -0
  867. /package/dist/{vocabulary-A7ZBBU65.js.map → vocabulary-6XMG22NZ.js.map} +0 -0
  868. /package/dist/{wsi.direct-JJGIAH6A.js.map → wsi.direct-EJ2ENH64.js.map} +0 -0
@@ -1,93 +0,0 @@
1
- import {
2
- SunburstChart,
3
- getPlotConfig
4
- } from "./chunk-R55JRVX7.js";
5
- import {
6
- LINK,
7
- TEXT_DARK
8
- } from "./chunk-7SFK32JP.js";
9
- import "./chunk-4ASBDE27.js";
10
- import "./chunk-HJ6L54YS.js";
11
- import "./chunk-OF6FDDKV.js";
12
- import "./chunk-CNFTQSNE.js";
13
- import "./chunk-RIHO7ZD5.js";
14
- import "./chunk-TVJOSRCH.js";
15
- import "./chunk-3CIL7KH7.js";
16
- import "./chunk-T4XPCSLP.js";
17
- import "./chunk-4TJO2DGU.js";
18
- import "./chunk-W5J3LTYS.js";
19
- import "./chunk-MHWYRNGA.js";
20
- import "./chunk-JHLF2ZC2.js";
21
- import "./chunk-WJLRU5OF.js";
22
- import "./chunk-HBNB5TRH.js";
23
- import "./chunk-PF4DSFDR.js";
24
- import "./chunk-4OLM3KSB.js";
25
- import "./chunk-PWYMHUXY.js";
26
- import "./chunk-TLT4YIG3.js";
27
- import "./chunk-5R63Q5KH.js";
28
- import "./chunk-I6Y4O3RR.js";
29
- import "./chunk-Q5RDQNIT.js";
30
- import "./chunk-HS5PO5ZQ.js";
31
-
32
- // plots/sunburst/aboutSunburst.ts
33
- var AboutSunburst = class {
34
- constructor(holder, app, onOpen) {
35
- this.app = app;
36
- this.onOpen = onOpen;
37
- const div = holder.append("div").attr("data-testid", "sjpp-about-sunburst").style("white-space", "normal");
38
- this.chart = new SunburstChart({
39
- holder: div,
40
- app,
41
- // the Rings box and the stats close to the chart, 12px from it on both sides
42
- gap: 6,
43
- // a plot of the selection is shown in the plots tab, as the About tab's launch items are
44
- beforeLaunch: () => app.dispatch({ type: "tab_set", activeTab: 1 })
45
- });
46
- }
47
- /** draw the counts of the app state's filter, unless they are shown already */
48
- async update(appState) {
49
- const termfilter = appState.termfilter;
50
- const sig = JSON.stringify(termfilter);
51
- if (sig == this.filterShown) return;
52
- this.filterShown = sig;
53
- this.ringsLoaded ??= getPlotConfig({}, this.app).then((config) => {
54
- this.twLst = config.twLst;
55
- this.renderRings();
56
- return config.twLst;
57
- });
58
- let twLst;
59
- try {
60
- twLst = await this.ringsLoaded;
61
- } catch (e) {
62
- this.ringsLoaded = void 0;
63
- this.filterShown = void 0;
64
- this.chart.dom.errdiv.style("display", "").text(e?.message || String(e));
65
- return;
66
- }
67
- const drawn = await this.chart.update({
68
- genome: appState.vocab.genome,
69
- dslabel: appState.vocab.dslabel,
70
- twLst,
71
- termfilter,
72
- colors: appState.termdbConfig?.sunburst?.colors
73
- });
74
- if (drawn === false && this.filterShown == sig) this.filterShown = void 0;
75
- }
76
- /** one line per ring with its term name, then the link to the full chart */
77
- renderRings() {
78
- for (const [i, tw] of this.twLst.entries()) {
79
- this.chart.ringLine(i).append("div").style("font-size", ".9em").style("color", TEXT_DARK).style("overflow", "hidden").style("white-space", "nowrap").style("text-overflow", "ellipsis").attr("title", tw.term.name).text(tw.term.name);
80
- }
81
- this.chart.dom.rings.body.append("div").attr("data-testid", "sjpp-about-sunburst-open").attr("role", "button").style("margin-top", "10px").style("font-size", ".85em").style("color", LINK).style("cursor", "pointer").text("Edit rings in the full chart \u203A").attr("tabindex", 0).on("click", this.onOpen).on("keydown", (event) => {
82
- if (event.key == "Enter" || event.key == " ") {
83
- event.preventDefault();
84
- this.onOpen();
85
- }
86
- });
87
- this.chart.markShownRings();
88
- }
89
- };
90
- export {
91
- AboutSunburst
92
- };
93
- //# sourceMappingURL=aboutSunburst-2T5SLCCB.js.map
@@ -1,29 +0,0 @@
1
- import {
2
- openSandbox
3
- } from "./chunk-BGYZJXYZ.js";
4
- import "./chunk-4ASBDE27.js";
5
- import "./chunk-HJ6L54YS.js";
6
- import "./chunk-OF6FDDKV.js";
7
- import "./chunk-CNFTQSNE.js";
8
- import "./chunk-RIHO7ZD5.js";
9
- import "./chunk-TVJOSRCH.js";
10
- import "./chunk-3CIL7KH7.js";
11
- import "./chunk-T4XPCSLP.js";
12
- import "./chunk-4TJO2DGU.js";
13
- import "./chunk-W5J3LTYS.js";
14
- import "./chunk-MHWYRNGA.js";
15
- import "./chunk-JHLF2ZC2.js";
16
- import "./chunk-WJLRU5OF.js";
17
- import "./chunk-HBNB5TRH.js";
18
- import "./chunk-PF4DSFDR.js";
19
- import "./chunk-4OLM3KSB.js";
20
- import "./chunk-PWYMHUXY.js";
21
- import "./chunk-TLT4YIG3.js";
22
- import "./chunk-5R63Q5KH.js";
23
- import "./chunk-I6Y4O3RR.js";
24
- import "./chunk-Q5RDQNIT.js";
25
- import "./chunk-HS5PO5ZQ.js";
26
- export {
27
- openSandbox
28
- };
29
- //# sourceMappingURL=adSandbox-GFF6ZCRM.js.map
@@ -1,542 +0,0 @@
1
- import {
2
- PlotBase,
3
- Tabs
4
- } from "./chunk-4ASBDE27.js";
5
- import "./chunk-HJ6L54YS.js";
6
- import "./chunk-OF6FDDKV.js";
7
- import {
8
- Menu
9
- } from "./chunk-CNFTQSNE.js";
10
- import "./chunk-RIHO7ZD5.js";
11
- import "./chunk-TVJOSRCH.js";
12
- import "./chunk-3CIL7KH7.js";
13
- import "./chunk-T4XPCSLP.js";
14
- import {
15
- dofetch3
16
- } from "./chunk-4TJO2DGU.js";
17
- import "./chunk-W5J3LTYS.js";
18
- import "./chunk-MHWYRNGA.js";
19
- import "./chunk-JHLF2ZC2.js";
20
- import {
21
- TermTypes,
22
- arc_default,
23
- collide_default,
24
- getColors,
25
- simulation_default,
26
- x_default,
27
- y_default
28
- } from "./chunk-WJLRU5OF.js";
29
- import {
30
- copyMerge,
31
- getCompInit
32
- } from "./chunk-HBNB5TRH.js";
33
- import "./chunk-PF4DSFDR.js";
34
- import {
35
- enclose_default,
36
- siblings_default,
37
- sqrt
38
- } from "./chunk-4OLM3KSB.js";
39
- import "./chunk-PWYMHUXY.js";
40
- import "./chunk-TLT4YIG3.js";
41
- import "./chunk-5R63Q5KH.js";
42
- import {
43
- select_default
44
- } from "./chunk-I6Y4O3RR.js";
45
- import "./chunk-Q5RDQNIT.js";
46
- import "./chunk-HS5PO5ZQ.js";
47
-
48
- // plots/animatedBubbleChart.ts
49
- var defaultConfig = { chartType: "animatedBubbleChart" };
50
- var SPLIT_W = 1100;
51
- var SPLIT_H = 900;
52
- var MIN_R = 6;
53
- var MAX_R = 43;
54
- var INNER_CIRCLE_RATIO = 0.75;
55
- var RING_GAP = 1;
56
- var PADDING = 0;
57
- var HOVER_SCALE = 1.2;
58
- var HOVER_COLLIDE_BOOST = 1.4;
59
- var HOVER_REPEL_REACH = 91;
60
- var HOVER_REPEL_STRENGTH = 0.17;
61
- var GRAVITY_STRENGTH = 0.28;
62
- var HOVER_GRAVITY = 0.045;
63
- var AnimatedBubbleChart = class _AnimatedBubbleChart extends PlotBase {
64
- constructor(opts, api) {
65
- super(opts, api);
66
- this.simulation = null;
67
- this.selectedRankingKey = null;
68
- this.groupBy = "all";
69
- // State for the split-view toggle. Stored on the instance so the toggle handler
70
- // can recompute layout + restart the simulation without re-fetching data.
71
- this.currentNodes = [];
72
- this.currentAssays = [];
73
- // 'all'-mode packed-cluster enclosing radius (+slack); set by computeHomes and used by
74
- // the per-tick circular clamp, so we don't pack the same nodes twice.
75
- this.allModeBoundaryR = 0;
76
- this.modalityLabelsSel = null;
77
- // Computed each time we enter split mode: where each modality's sub-cluster sits.
78
- // Sizes vary because we hierarchically pack groups by their natural cluster radii.
79
- // `topY` is the topmost EDGE of the cluster (min(homeY - outerR)) — bubble radii
80
- // aren't scaled with the layout, so the visual extent reaches farther up than
81
- // `cy - r*scale`. Labels use this so they always sit clear of every bubble.
82
- this.groupCenters = [];
83
- this.svgSel = null;
84
- this.wrapperSel = null;
85
- // Computed by `computeHomes` from the actual home positions + bubble radii.
86
- // Drives the wrapper's visible width/height so the chart frame hugs the cluster
87
- // instead of inheriting the much larger fixed SPLIT canvas size.
88
- this.contentBbox = {
89
- minX: 0,
90
- minY: 0,
91
- maxX: 0,
92
- maxY: 0
93
- };
94
- this.BBOX_PAD = 20;
95
- this.type = _AnimatedBubbleChart.type;
96
- this.components = {};
97
- }
98
- static {
99
- this.type = "animatedBubbleChart";
100
- }
101
- /** Internal SVG coordinate space — fixed, used by computeHomes for layout math. */
102
- canvasW() {
103
- return SPLIT_W;
104
- }
105
- canvasH() {
106
- return SPLIT_H;
107
- }
108
- /** Visible viewport — sized to the actual content bbox + padding, not a fixed constant. */
109
- viewportW() {
110
- return Math.max(50, this.contentBbox.maxX - this.contentBbox.minX + 2 * this.BBOX_PAD);
111
- }
112
- viewportH() {
113
- return Math.max(50, this.contentBbox.maxY - this.contentBbox.minY + 2 * this.BBOX_PAD);
114
- }
115
- async init() {
116
- const holder = this.opts.holder.append("div").style("padding", "10px");
117
- this.dom = {
118
- holder,
119
- controls: holder.append("div").style("display", "flex").style("gap", "14px").style("align-items", "center").style("margin-bottom", "10px"),
120
- body: holder.append("div"),
121
- tip: new Menu({ padding: "" }),
122
- header: this.opts.header
123
- };
124
- if (this.dom.header) this.dom.header.html("Bubble Chart");
125
- }
126
- getState(appState) {
127
- const config = appState.plots.find((p) => p.id === this.id);
128
- if (!config) throw `No plot with id='${this.id}' found`;
129
- return { config };
130
- }
131
- async main() {
132
- await this.fetchAndRender(this.selectedRankingKey ?? void 0);
133
- }
134
- async fetchAndRender(rankingKey) {
135
- const body = {
136
- genome: this.app.opts.state.vocab.genome,
137
- dslabel: this.app.opts.state.vocab.dslabel
138
- };
139
- if (rankingKey) body.rankingKey = rankingKey;
140
- const data = await dofetch3("termdb/animatedBubbleChart", { body });
141
- if (this.simulation) {
142
- this.simulation.stop();
143
- this.simulation = null;
144
- }
145
- if (data.error) {
146
- if (data.rankingKeys?.length) this.renderControls(data.rankingKeys, rankingKey ?? data.rankingKeys[0]);
147
- this.dom.body.selectAll("*").remove();
148
- this.dom.body.append("div").style("padding", "20px").style("color", "#b00020").text(`Error: ${data.error}`);
149
- return;
150
- }
151
- this.selectedRankingKey = data.selectedRankingKey;
152
- this.renderControls(data.rankingKeys, data.selectedRankingKey);
153
- this.dom.body.selectAll("*").remove();
154
- if (!data.bubbles?.length) {
155
- this.dom.body.append("div").style("padding", "20px").style("color", "#666").text("No data in the selected ranking file.");
156
- return;
157
- }
158
- const container = this.dom.body.append("div").style("display", "flex").style("gap", "24px").style("align-items", "flex-start").style("flex-wrap", "nowrap");
159
- const colorScale = getColors(data.assays.length).domain(data.assays);
160
- const assayColors = {};
161
- for (const a of data.assays) assayColors[a] = colorScale(a);
162
- this.renderBubbles(container, data.bubbles, assayColors);
163
- this.renderLegend(container, data.assays, assayColors);
164
- }
165
- renderControls(rankingKeys, current) {
166
- this.dom.controls.selectAll("*").remove();
167
- const sel = this.dom.controls.append("select").style("padding", "4px 8px").style("min-width", "200px");
168
- sel.selectAll("option").data(rankingKeys).enter().append("option").attr("value", (d) => d).text((d) => d);
169
- sel.property("value", current);
170
- sel.on("change", () => this.fetchAndRender(sel.node().value));
171
- const tabsHolder = this.dom.controls.append("div");
172
- const tabsToggle = new Tabs({
173
- holder: tabsHolder,
174
- noContent: true,
175
- tabs: [
176
- {
177
- label: "Combined",
178
- active: this.groupBy === "all",
179
- callback: () => {
180
- if (this.groupBy === "all") return;
181
- this.groupBy = "all";
182
- this.applyGrouping();
183
- }
184
- },
185
- {
186
- label: "Split by dominant data type",
187
- active: this.groupBy === "modality",
188
- callback: () => {
189
- if (this.groupBy === "modality") return;
190
- this.groupBy = "modality";
191
- this.applyGrouping();
192
- }
193
- }
194
- ]
195
- });
196
- tabsToggle.main();
197
- }
198
- /** Find the modality (assay) that contributes the largest slice to this gene's wheel. */
199
- dominantAssay(node) {
200
- let bestAssay = node.slices[0]?.assay ?? this.currentAssays[0];
201
- let bestAngle = -1;
202
- for (const s of node.slices) {
203
- if (s.angle > bestAngle) {
204
- bestAngle = s.angle;
205
- bestAssay = s.assay;
206
- }
207
- }
208
- return bestAssay;
209
- }
210
- /** Compute homeX/homeY on every node based on the current `groupBy` mode. */
211
- computeHomes() {
212
- const nodes = this.currentNodes;
213
- if (!nodes.length) return;
214
- const W = this.canvasW();
215
- const H = this.canvasH();
216
- if (this.groupBy === "all") {
217
- const packInputs = nodes.map((n) => ({ r: n.outerR, x: 0, y: 0 }));
218
- siblings_default(packInputs);
219
- const enclose = enclose_default(packInputs) ?? { x: 0, y: 0, r: Math.min(W, H) / 2 };
220
- const dx2 = W / 2 - enclose.x;
221
- const dy2 = H / 2 - enclose.y;
222
- for (let i = 0; i < nodes.length; i++) {
223
- nodes[i].homeX = packInputs[i].x + dx2;
224
- nodes[i].homeY = packInputs[i].y + dy2;
225
- }
226
- this.allModeBoundaryR = enclose.r + 2;
227
- this.groupCenters = [];
228
- this.recordContentBbox();
229
- return;
230
- }
231
- const assays = this.currentAssays;
232
- const LABEL_GAP = 200;
233
- const buckets = /* @__PURE__ */ new Map();
234
- for (const a of assays) buckets.set(a, []);
235
- for (const n of nodes) buckets.get(this.dominantAssay(n))?.push(n);
236
- const layouts = [];
237
- for (const assay of assays) {
238
- const groupNodes = buckets.get(assay) ?? [];
239
- if (!groupNodes.length) continue;
240
- const packs = groupNodes.map((n) => ({ r: n.outerR, x: 0, y: 0 }));
241
- siblings_default(packs);
242
- const enclose = enclose_default(packs) ?? { x: 0, y: 0, r: 0 };
243
- let naturalExtent = 0;
244
- for (let j = 0; j < groupNodes.length; j++) {
245
- const dx2 = packs[j].x - enclose.x;
246
- const dy2 = packs[j].y - enclose.y;
247
- const reach = Math.sqrt(dx2 * dx2 + dy2 * dy2) + groupNodes[j].outerR;
248
- if (reach > naturalExtent) naturalExtent = reach;
249
- }
250
- layouts.push({ assay, nodes: groupNodes, packs, enclose, naturalExtent });
251
- }
252
- const superCircles = layouts.map((g) => ({ r: g.naturalExtent + LABEL_GAP, x: 0, y: 0 }));
253
- siblings_default(superCircles);
254
- const overallEnclose = enclose_default(superCircles) ?? { x: 0, y: 0, r: 1 };
255
- const margin = 10;
256
- const maxR = Math.min(W, H) / 2 - margin;
257
- const scale = overallEnclose.r > maxR ? maxR / overallEnclose.r : 1;
258
- const dx = W / 2 - overallEnclose.x * scale;
259
- const dy = H / 2 - overallEnclose.y * scale;
260
- this.groupCenters = [];
261
- for (let i = 0; i < layouts.length; i++) {
262
- const g = layouts[i];
263
- const groupCx = superCircles[i].x * scale + dx;
264
- const groupCy = superCircles[i].y * scale + dy;
265
- const offX = groupCx - g.enclose.x;
266
- const offY = groupCy - g.enclose.y;
267
- for (let j = 0; j < g.nodes.length; j++) {
268
- g.nodes[j].homeX = g.packs[j].x + offX;
269
- g.nodes[j].homeY = g.packs[j].y + offY;
270
- }
271
- this.groupCenters.push({
272
- assay: g.assay,
273
- cx: groupCx,
274
- cy: groupCy,
275
- r: g.naturalExtent,
276
- topY: groupCy - g.naturalExtent
277
- });
278
- }
279
- let minX = Infinity, minY = Infinity, maxX = -Infinity, maxY = -Infinity;
280
- for (const n of nodes) {
281
- if (n.homeX - n.outerR < minX) minX = n.homeX - n.outerR;
282
- if (n.homeY - n.outerR < minY) minY = n.homeY - n.outerR;
283
- if (n.homeX + n.outerR > maxX) maxX = n.homeX + n.outerR;
284
- if (n.homeY + n.outerR > maxY) maxY = n.homeY + n.outerR;
285
- }
286
- if (Number.isFinite(minX)) {
287
- const shiftX = W / 2 - (minX + maxX) / 2;
288
- const shiftY = H / 2 - (minY + maxY) / 2;
289
- for (const n of nodes) {
290
- n.homeX += shiftX;
291
- n.homeY += shiftY;
292
- }
293
- for (const g of this.groupCenters) {
294
- g.cx += shiftX;
295
- g.cy += shiftY;
296
- g.topY += shiftY;
297
- }
298
- }
299
- this.recordContentBbox();
300
- }
301
- /** Record the FINAL content bbox (after recentering) so the wrapper can hug the
302
- * cluster instead of inheriting a fixed canvas size. Called by both modes. */
303
- recordContentBbox() {
304
- const nodes = this.currentNodes;
305
- if (!nodes.length) return;
306
- let bx0 = Infinity, by0 = Infinity, bx1 = -Infinity, by1 = -Infinity;
307
- for (const n of nodes) {
308
- if (n.homeX - n.outerR < bx0) bx0 = n.homeX - n.outerR;
309
- if (n.homeY - n.outerR < by0) by0 = n.homeY - n.outerR;
310
- if (n.homeX + n.outerR > bx1) bx1 = n.homeX + n.outerR;
311
- if (n.homeY + n.outerR > by1) by1 = n.homeY + n.outerR;
312
- }
313
- if (this.groupBy === "modality") {
314
- for (const g of this.groupCenters) {
315
- const labelY = g.topY - 32;
316
- if (labelY < by0) by0 = labelY;
317
- }
318
- }
319
- if (Number.isFinite(bx0)) {
320
- this.contentBbox = { minX: bx0, minY: by0, maxX: bx1, maxY: by1 };
321
- }
322
- }
323
- /** Toggle handler — recompute homes for the current groupBy and reheat the simulation. */
324
- applyGrouping() {
325
- this.computeHomes();
326
- if (this.wrapperSel) {
327
- this.wrapperSel.transition().duration(900).style("width", `${this.viewportW()}px`).style("height", `${this.viewportH()}px`);
328
- }
329
- if (this.svgSel) {
330
- this.svgSel.transition().duration(900).style("left", `${this.BBOX_PAD - this.contentBbox.minX}px`).style("top", `${this.BBOX_PAD - this.contentBbox.minY}px`);
331
- }
332
- const centerByAssay = new Map(this.groupCenters.map((g) => [g.assay, g]));
333
- if (this.modalityLabelsSel) {
334
- const labels = this.modalityLabelsSel.selectAll("text");
335
- if (this.groupBy === "modality") {
336
- labels.transition().duration(900).attr("opacity", (assay) => centerByAssay.has(assay) ? 1 : 0).attr("x", (assay) => centerByAssay.get(assay)?.cx ?? 0).attr("y", (assay) => {
337
- const g = centerByAssay.get(assay);
338
- return g ? g.cy - g.r - 12 : 0;
339
- });
340
- } else {
341
- labels.transition().duration(400).attr("opacity", 0);
342
- }
343
- }
344
- if (this.simulation) {
345
- this.simulation.force("x", x_default((d) => d.homeX).strength(GRAVITY_STRENGTH)).force("y", y_default((d) => d.homeY).strength(GRAVITY_STRENGTH)).velocityDecay(0.55).alpha(0.6).alphaDecay(0.018).restart();
346
- setTimeout(() => {
347
- if (this.simulation) this.simulation.velocityDecay(0.4).alphaDecay(0.022);
348
- }, 2500);
349
- }
350
- }
351
- renderBubbles(container, bubbles, assayColors) {
352
- const maxRank = Math.max(...bubbles.map((b) => b.integrativeRank));
353
- const sizeScale = sqrt().domain([1, maxRank]).range([MAX_R, MIN_R]).clamp(true);
354
- const nodes = bubbles.map((b) => {
355
- const outerR = sizeScale(b.integrativeRank);
356
- const innerR = outerR * INNER_CIRCLE_RATIO;
357
- const slices = [];
358
- let cum = 0;
359
- for (const s of b.slices) {
360
- const start = cum;
361
- const end = cum + s.angle;
362
- slices.push({ ...s, startAngle: start, endAngle: end });
363
- cum = end;
364
- }
365
- return {
366
- gene: b.gene,
367
- integrativeRank: b.integrativeRank,
368
- orderStatQ: b.orderStatQ,
369
- pValue: b.pValue,
370
- fdr: b.fdr,
371
- slices,
372
- innerR,
373
- outerR,
374
- // Seed positions in a small jitter around center so the simulation pulls them outward to home
375
- x: this.canvasW() / 2 + (Math.random() - 0.5) * 80,
376
- y: this.canvasH() / 2 + (Math.random() - 0.5) * 80,
377
- homeX: 0,
378
- // filled in by packSiblings below
379
- homeY: 0,
380
- hovered: false
381
- };
382
- });
383
- this.currentNodes = nodes;
384
- this.currentAssays = Object.keys(assayColors);
385
- this.computeHomes();
386
- const wrapper = container.append("div").style("position", "relative").style("overflow", "hidden").style("width", `${this.viewportW()}px`).style("height", `${this.viewportH()}px`);
387
- this.wrapperSel = wrapper;
388
- const svg = wrapper.append("svg").attr("width", this.canvasW()).attr("height", this.canvasH()).style("position", "absolute").style("left", `${this.BBOX_PAD - this.contentBbox.minX}px`).style("top", `${this.BBOX_PAD - this.contentBbox.minY}px`);
389
- this.svgSel = svg;
390
- const root = svg.append("g");
391
- const arcGen = arc_default().startAngle((d) => d.startAngle).endAngle((d) => d.endAngle);
392
- const groups = root.selectAll("g.sjpp-abc-bubble").data(nodes).enter().append("g").attr("class", "sjpp-abc-bubble").attr("transform", (d) => `translate(${d.x},${d.y})`).style("cursor", "pointer").attr("role", "button").attr("tabindex", 0).attr("aria-label", (d) => `Open protein view for ${d.gene}`);
393
- groups.append("circle").attr("class", "hit-area").attr("r", (d) => d.outerR).attr("fill", "transparent");
394
- groups.each(function(d) {
395
- const slicesG = select_default(this).append("g").attr("class", "ring");
396
- const visible = d.slices.filter((s) => s.angle > 0);
397
- slicesG.selectAll("path").data(visible).enter().append("path").attr("fill", (s) => assayColors[s.assay] ?? "#999").attr("stroke", "#fff").attr("stroke-width", 0.8).attr("opacity", 0).attr(
398
- "d",
399
- (s) => arcGen({
400
- ...s,
401
- innerRadius: d.innerR + RING_GAP,
402
- outerRadius: d.outerR
403
- })
404
- );
405
- });
406
- groups.append("circle").attr("class", "inner").attr("r", 0).attr("fill", "#fff").attr("stroke", "#333").attr("stroke-width", 1);
407
- const labelFontSize = (d) => {
408
- const byRadius = d.innerR * 0.72;
409
- const maxByWidth = d.innerR * 1.8 / Math.max(d.gene.length * 0.6, 1);
410
- return Math.max(5, Math.min(byRadius, maxByWidth, 20));
411
- };
412
- groups.append("text").attr("text-anchor", "middle").attr("dominant-baseline", "central").attr("font-weight", "bold").attr("font-size", (d) => `${labelFontSize(d)}px`).attr("fill", "#222").attr("pointer-events", "none").attr("opacity", 0).text((d) => d.gene);
413
- const tip = this.dom.tip;
414
- groups.on("mouseenter", (event, d) => {
415
- d.hovered = true;
416
- if (this.simulation) {
417
- this.simulation.force("x").strength(HOVER_GRAVITY);
418
- this.simulation.force("y").strength(HOVER_GRAVITY);
419
- this.simulation.alpha(0.5).restart();
420
- }
421
- tip.clear().show(event.clientX, event.clientY);
422
- const t = tip.d.append("div").style("padding", "8px").style("font-size", "13px").style("min-width", "220px");
423
- t.append("div").style("font-weight", "bold").style("font-size", "15px").style("margin-bottom", "4px").text(d.gene);
424
- t.append("div").text(`Integrative rank: ${d.integrativeRank}`);
425
- if (d.orderStatQ != null) t.append("div").text(`Order statistic Q: ${d.orderStatQ.toExponential(3)}`);
426
- if (d.pValue != null)
427
- t.append("div").text(`P value: ${d.pValue >= 1e-4 ? d.pValue.toFixed(4) : d.pValue.toExponential(3)}`);
428
- if (d.fdr != null) t.append("div").text(`FDR: ${d.fdr >= 1e-4 ? d.fdr.toFixed(4) : d.fdr.toExponential(3)}`);
429
- const table = t.append("table").style("margin-top", "6px").style("border-collapse", "collapse").style("font-size", "12px");
430
- const header = table.append("tr");
431
- header.append("th").style("text-align", "left").style("padding", "2px 6px").text("Data Type");
432
- header.append("th").style("text-align", "right").style("padding", "2px 6px").text("Rank");
433
- header.append("th").style("text-align", "right").style("padding", "2px 6px").text("Share");
434
- for (const s of d.slices) {
435
- const row = table.append("tr");
436
- const swatch = row.append("td").style("padding", "2px 6px");
437
- swatch.append("span").style("display", "inline-block").style("width", "10px").style("height", "10px").style("background", assayColors[s.assay] ?? "#999").style("margin-right", "6px").style("vertical-align", "middle");
438
- swatch.append("span").text(s.assay);
439
- row.append("td").style("padding", "2px 6px").style("text-align", "right").text(s.rank == null ? "NA" : String(s.rank));
440
- row.append("td").style("padding", "2px 6px").style("text-align", "right").text(s.weight == null ? "\u2014" : `${(s.weight * 100).toFixed(1)}%`);
441
- }
442
- }).on("mouseleave", (_event, d) => {
443
- d.hovered = false;
444
- if (this.simulation) {
445
- this.simulation.force("x").strength(GRAVITY_STRENGTH);
446
- this.simulation.force("y").strength(GRAVITY_STRENGTH);
447
- this.simulation.alpha(0.25).restart();
448
- }
449
- tip.hide();
450
- }).on("click keydown", (event, d) => {
451
- if (event.type === "keydown") {
452
- const ke = event;
453
- if (ke.key !== "Enter" && ke.key !== " ") return;
454
- ke.preventDefault();
455
- }
456
- tip.hide();
457
- this.app.dispatch({
458
- type: "plot_create",
459
- config: {
460
- chartType: "proteinView",
461
- tw: {
462
- term: {
463
- gene: d.gene,
464
- name: d.gene,
465
- type: TermTypes.PROTEOME_ABUNDANCE
466
- }
467
- }
468
- }
469
- });
470
- });
471
- groups.select("circle.inner").transition().duration(900).attr("r", (d) => d.innerR);
472
- groups.select("g.ring").selectAll("path").transition().delay(200).duration(900).attr("opacity", 0.95);
473
- groups.select("text").transition().delay(500).duration(600).attr("opacity", 1);
474
- const assayNames = this.currentAssays;
475
- const labelsG = svg.append("g").attr("class", "modality-labels");
476
- labelsG.selectAll("text").data(assayNames).enter().append("text").attr("text-anchor", "middle").attr("dominant-baseline", "alphabetic").attr("font-size", "13px").attr("font-weight", "bold").attr("paint-order", "stroke").attr("stroke", "#fff").attr("stroke-width", 3).attr("stroke-linejoin", "round").attr("fill", (d) => assayColors[d] ?? "#333").attr("opacity", 0).attr("x", this.canvasW() / 2).attr("y", 12).text((d) => d);
477
- this.modalityLabelsSel = labelsG;
478
- if (this.groupBy === "modality") {
479
- const centerByAssay = new Map(this.groupCenters.map((g) => [g.assay, g]));
480
- labelsG.selectAll("text").attr("opacity", (assay) => centerByAssay.has(assay) ? 1 : 0).attr("x", (assay) => centerByAssay.get(assay)?.cx ?? this.canvasW() / 2).attr("y", (assay) => {
481
- const g = centerByAssay.get(assay);
482
- return g ? g.cy - g.r - 8 : 12;
483
- });
484
- }
485
- const collideR = (d) => (d.hovered ? d.outerR * HOVER_COLLIDE_BOOST : d.outerR) + PADDING;
486
- function hoverRepel(alpha) {
487
- const h = nodes.find((n) => n.hovered);
488
- if (!h) return;
489
- const sizeRatio = h.outerR / MAX_R;
490
- const reach = HOVER_REPEL_REACH * sizeRatio;
491
- const strength = HOVER_REPEL_STRENGTH * sizeRatio;
492
- if (reach < 1) return;
493
- for (const n of nodes) {
494
- if (n === h) continue;
495
- const dx = n.x - h.x;
496
- const dy = n.y - h.y;
497
- const dist = Math.sqrt(dx * dx + dy * dy) || 0.01;
498
- if (dist >= reach) continue;
499
- const falloff = 1 - dist / reach;
500
- const push = strength * falloff * alpha;
501
- n.vx = (n.vx ?? 0) + dx / dist * push * reach;
502
- n.vy = (n.vy ?? 0) + dy / dist * push * reach;
503
- }
504
- }
505
- this.simulation = simulation_default(nodes).force("collide", collide_default(collideR).strength(1).iterations(2)).force("x", x_default((d) => d.homeX).strength(GRAVITY_STRENGTH)).force("y", y_default((d) => d.homeY).strength(GRAVITY_STRENGTH)).force("hoverRepel", hoverRepel).alpha(1).alphaDecay(0.022).alphaMin(1e-3).on("tick", () => {
506
- if (this.groupBy === "all") {
507
- const cxC = this.canvasW() / 2;
508
- const cyC = this.canvasH() / 2;
509
- for (const d of nodes) {
510
- const ddx = d.x - cxC;
511
- const ddy = d.y - cyC;
512
- const dist = Math.sqrt(ddx * ddx + ddy * ddy) || 1e-4;
513
- const maxDist = this.allModeBoundaryR - d.outerR;
514
- if (dist > maxDist) {
515
- d.x = cxC + ddx * maxDist / dist;
516
- d.y = cyC + ddy * maxDist / dist;
517
- }
518
- }
519
- }
520
- groups.attr("transform", (d) => `translate(${d.x},${d.y})${d.hovered ? ` scale(${HOVER_SCALE})` : ""}`);
521
- });
522
- }
523
- renderLegend(container, assays, assayColors) {
524
- const legend = container.append("div").style("display", "flex").style("flex-direction", "column").style("gap", "6px").style("padding", "4px 0").style("min-width", "160px");
525
- legend.append("div").style("font-weight", "bold").style("font-size", "13px").style("margin-bottom", "4px").text("Data Type");
526
- for (const assay of assays) {
527
- const row = legend.append("div").style("display", "flex").style("align-items", "center").style("gap", "8px").style("font-size", "12px");
528
- row.append("span").style("display", "inline-block").style("width", "14px").style("height", "14px").style("background", assayColors[assay] ?? "#999").style("border", "1px solid #ccc");
529
- row.append("span").text(assay);
530
- }
531
- }
532
- };
533
- var componentInit = getCompInit(AnimatedBubbleChart);
534
- async function getPlotConfig(opts) {
535
- const config = structuredClone(defaultConfig);
536
- return copyMerge(config, opts);
537
- }
538
- export {
539
- componentInit,
540
- getPlotConfig
541
- };
542
- //# sourceMappingURL=animatedBubbleChart-PUPXCFJW.js.map