@sjcrh/proteinpaint-client 2.222.0 → 2.224.0

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (868) hide show
  1. package/dist/2dmaf-AHG6N6GX.js +1362 -0
  2. package/dist/AggMatrixInput-A4EATVXG.js +402 -0
  3. package/dist/AggregateMatrix-3D36XP7Q.js +37 -0
  4. package/dist/AppHeader-LBFNK6BI.js +826 -0
  5. package/dist/BoxPlot-JNISSUMV.js +1229 -0
  6. package/dist/CorrelationVolcano-BXXFXVHQ.js +613 -0
  7. package/dist/Cuminc-PYG3TJSE.js +1217 -0
  8. package/dist/DE-QGNB5JKB.js +85 -0
  9. package/dist/DEinput-YVXCVTCX.js +479 -0
  10. package/dist/DM-D37YHRJL.js +86 -0
  11. package/dist/DifferentialAnalysis-TFWK7UE7.js +236 -0
  12. package/dist/Disco-PXBROYMP.js +3384 -0
  13. package/dist/Disco.UI-XERJSEDE.js +239 -0
  14. package/dist/DmrPlot-G3QAPQ5I.js +361 -0
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  17. package/dist/GeneExpInput-EYNET6LR.js +38 -0
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  37. package/dist/ProteomeInput-4M2SXSJG.js +610 -0
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  143. package/dist/condition-ZDF5SRLZ.js +323 -0
  144. package/dist/controls-Z4URI2HB.js +30 -0
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  150. package/dist/dictionary-S4MSWVZV.js +109 -0
  151. package/dist/dnaMethylation-QMKO3DXK.js +29 -0
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  153. package/dist/dofetch-4P5F5ZGU.js +49 -0
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  163. package/dist/geneORA-NWJCROO7.js +269 -0
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  216. package/dist/proteinView-ZHNMVSLF.js +1346 -0
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  807. /package/dist/{selectGenomeWithTklst-LGBKEN3T.js.map → selectGenomeWithTklst-YQMYWVXF.js.map} +0 -0
  808. /package/dist/{singleCellCellType-ACQACM6W.js.map → singleCellCellType-AJEAQL4Y.js.map} +0 -0
  809. /package/dist/{singleCellCellType.unit.spec-WLGTJKOM.js.map → singleCellCellType.unit.spec-7YCO4VV7.js.map} +0 -0
  810. /package/dist/{singleCellGeneExpression-M4RPITJW.js.map → singleCellGeneExpression-LPDACSPJ.js.map} +0 -0
  811. /package/dist/{singleCellGeneExpression.unit.spec-N3VD6PUW.js.map → singleCellGeneExpression.unit.spec-JZHG5OAH.js.map} +0 -0
  812. /package/dist/{singleCellNumericValue-W6F44FJN.js.map → singleCellNumericValue-SDUSPCBR.js.map} +0 -0
  813. /package/dist/{singleCellNumericValue.unit.spec-JZNMY77I.js.map → singleCellNumericValue.unit.spec-VQSNCIJC.js.map} +0 -0
  814. /package/dist/{singleCellPlot-CCG2KSCO.js.map → singleCellPlot-5AAE5QGD.js.map} +0 -0
  815. /package/dist/{singlecell-I6H3Z7FT.js.map → singlecell-7XO5TLVF.js.map} +0 -0
  816. /package/dist/{singlecell-32P47E4I.js.map → singlecell-MUI27JKF.js.map} +0 -0
  817. /package/dist/{snp-7X2BXRQP.js.map → snp-2QX25UKB.js.map} +0 -0
  818. /package/dist/{snp.unit.spec-BJGWNSVR.js.map → snp.unit.spec-6B7ZUD7Q.js.map} +0 -0
  819. /package/dist/{snplocus-UOVS2GD6.js.map → snplocus-GMWNSSHV.js.map} +0 -0
  820. /package/dist/{snplst-JFVP4NG2.js.map → snplst-6NAHQAXI.js.map} +0 -0
  821. /package/dist/{spliceevent.a53ss.diagram-ETXJX57W.js.map → spliceevent.a53ss.diagram-WUHKYRWG.js.map} +0 -0
  822. /package/dist/{spliceevent.exonskip.diagram-C4JCEOXQ.js.map → spliceevent.exonskip.diagram-KAFGBL2I.js.map} +0 -0
  823. /package/dist/{spliceevent.noeventdiagram-4DD3Z4OM.js.map → spliceevent.noeventdiagram-SUBU5BLZ.js.map} +0 -0
  824. /package/dist/{ssGSEA-GOZOYROM.js.map → ssGSEA-V4W3E6MF.js.map} +0 -0
  825. /package/dist/{ssGSEA.unit.spec-J4DPFU4D.js.map → ssGSEA.unit.spec-DYMT2CCB.js.map} +0 -0
  826. /package/dist/{stattable-ICUZQHUF.js.map → stattable-DJCYOA6Y.js.map} +0 -0
  827. /package/dist/{studyCatalog-PCFXVOI3.js.map → studyCatalog-TOGQ24WQ.js.map} +0 -0
  828. /package/dist/{summarizeCnvGeneexp-DK6HNUFE.js.map → summarizeCnvGeneexp-6Z3VVSMQ.js.map} +0 -0
  829. /package/dist/{summarizeGeneexpSurvival-JLCR2VIX.js.map → summarizeGeneexpSurvival-REIPWAEJ.js.map} +0 -0
  830. /package/dist/{summarizeMutationCnv-CFAKT6IP.js.map → summarizeMutationCnv-OJNIJR55.js.map} +0 -0
  831. /package/dist/{summarizeMutationDiagnosis-5HMVSYMI.js.map → summarizeMutationDiagnosis-PVOTM3DF.js.map} +0 -0
  832. /package/dist/{summarizeMutationSurvival-GP2OQMUS.js.map → summarizeMutationSurvival-X7TV3EKS.js.map} +0 -0
  833. /package/dist/{summary-6K553VNS.js.map → summary-RNNIEEHQ.js.map} +0 -0
  834. /package/dist/{summary.integration.spec-MXERZOVY.js.map → summary.integration.spec-PEICP7YJ.js.map} +0 -0
  835. /package/dist/{summaryInput-V2G6HFJS.js.map → summaryInput-53MQOUXV.js.map} +0 -0
  836. /package/dist/{sunburst-6GKVNIRF.js.map → sunburst-MYKDYBVD.js.map} +0 -0
  837. /package/dist/{sunburst-YOVKC5G2.js.map → sunburst-OMNCQM26.js.map} +0 -0
  838. /package/dist/{survival-GHTV2ZPX.js.map → survival-3IECSQKM.js.map} +0 -0
  839. /package/dist/{survival-KF2QUWSM.js.map → survival-TQZXLQMK.js.map} +0 -0
  840. /package/dist/{survival.integration.spec-GVSQL4VB.js.map → survival.integration.spec-IMLRYIX2.js.map} +0 -0
  841. /package/dist/{svgraph-WN3JLEOC.js.map → svgraph-YE4MTHLA.js.map} +0 -0
  842. /package/dist/{svmr-ZZKBQFQK.js.map → svmr-KY3V2L4L.js.map} +0 -0
  843. /package/dist/{swimmer-XHORJEVI.js.map → swimmer-HO32NUCE.js.map} +0 -0
  844. /package/dist/{table-XQCTNHSZ.js.map → table-6VZK2B2G.js.map} +0 -0
  845. /package/dist/{termCollection-DXZQT7YT.js.map → termCollection-AMV35ML5.js.map} +0 -0
  846. /package/dist/{termCollection-HRM2NHLA.js.map → termCollection-ETWJLZJT.js.map} +0 -0
  847. /package/dist/{termCollection.unit.spec-BGULSLH6.js.map → termCollection.unit.spec-QHKLFPWO.js.map} +0 -0
  848. /package/dist/{termCollectionFractionSelection-TPNNP2ER.js.map → termCollectionFractionSelection-ZNMCUSN4.js.map} +0 -0
  849. /package/dist/{termCollectionFractionSelection.unit.spec-VONXAGZH.js.map → termCollectionFractionSelection.unit.spec-PO4BHCMC.js.map} +0 -0
  850. /package/dist/{tk-KPD6HTHR.js.map → tk-7OE7QMYG.js.map} +0 -0
  851. /package/dist/{tk-RCTQPQH7.js.map → tk-R6IBTAYE.js.map} +0 -0
  852. /package/dist/{tp.ui-MVNQLMAD.js.map → tp.ui-BGSBCIR7.js.map} +0 -0
  853. /package/dist/{tvs.categorical-4TKKU6HO.js.map → tvs.categorical-RTSI5L6T.js.map} +0 -0
  854. /package/dist/{tvs.condition-SARY3O5Y.js.map → tvs.condition-VBDUN33K.js.map} +0 -0
  855. /package/dist/{tvs.dt-XJ2MW2AP.js.map → tvs.dt-NP6556P7.js.map} +0 -0
  856. /package/dist/{tvs.dtcnv.categorical-H7FKTXH4.js.map → tvs.dtcnv.categorical-RERJRI5J.js.map} +0 -0
  857. /package/dist/{tvs.dtcnv.continuous-JQ62ZHER.js.map → tvs.dtcnv.continuous-UEVWYT3H.js.map} +0 -0
  858. /package/dist/{tvs.dtfusion-GC3DZ2BO.js.map → tvs.dtfusion-CRJ77JUK.js.map} +0 -0
  859. /package/dist/{tvs.dtitd-3SHGIDIB.js.map → tvs.dtitd-ZOCNVICE.js.map} +0 -0
  860. /package/dist/{tvs.dtsnvindel-BEDWZ4A2.js.map → tvs.dtsnvindel-LFWG54AQ.js.map} +0 -0
  861. /package/dist/{tvs.dtsv-HRIMULVD.js.map → tvs.dtsv-SNIZC3C6.js.map} +0 -0
  862. /package/dist/{tvs.multivalue-5VC7BLSZ.js.map → tvs.multivalue-UJS4743S.js.map} +0 -0
  863. /package/dist/{tvs.numeric-TGEC7G6A.js.map → tvs.numeric-KKMUTKSJ.js.map} +0 -0
  864. /package/dist/{tvs.samplelst-Q6EYAUQZ.js.map → tvs.samplelst-AW3IY3CB.js.map} +0 -0
  865. /package/dist/{tvs.survival-NJ3DTZIG.js.map → tvs.survival-LH2Z3WTM.js.map} +0 -0
  866. /package/dist/{tvs.termCollection-TVVLPSTG.js.map → tvs.termCollection-OQNMYVX5.js.map} +0 -0
  867. /package/dist/{vocabulary-A7ZBBU65.js.map → vocabulary-6XMG22NZ.js.map} +0 -0
  868. /package/dist/{wsi.direct-JJGIAH6A.js.map → wsi.direct-EJ2ENH64.js.map} +0 -0
@@ -0,0 +1,451 @@
1
+ import {
2
+ font
3
+ } from "./chunk-U45YALDI.js";
4
+ import "./chunk-HJ6L54YS.js";
5
+ import "./chunk-KZXFNO75.js";
6
+ import "./chunk-CNFTQSNE.js";
7
+ import "./chunk-RIHO7ZD5.js";
8
+ import "./chunk-TVJOSRCH.js";
9
+ import "./chunk-3CIL7KH7.js";
10
+ import "./chunk-T4XPCSLP.js";
11
+ import "./chunk-KBTFT76L.js";
12
+ import "./chunk-W5J3LTYS.js";
13
+ import "./chunk-MHWYRNGA.js";
14
+ import "./chunk-JHLF2ZC2.js";
15
+ import {
16
+ exoncolor
17
+ } from "./chunk-WJLRU5OF.js";
18
+ import "./chunk-HBNB5TRH.js";
19
+ import "./chunk-PF4DSFDR.js";
20
+ import "./chunk-4OLM3KSB.js";
21
+ import "./chunk-PWYMHUXY.js";
22
+ import "./chunk-TLT4YIG3.js";
23
+ import "./chunk-5R63Q5KH.js";
24
+ import "./chunk-I6Y4O3RR.js";
25
+ import "./chunk-Q5RDQNIT.js";
26
+ import "./chunk-HS5PO5ZQ.js";
27
+
28
+ // src/spliceevent.noeventdiagram.js
29
+ var intronwidth = 30;
30
+ var exonxpad = 5;
31
+ var junctionBcolor = "#990000";
32
+ var exonheight = 20;
33
+ var fontsize = 14;
34
+ var junctionheight = 20;
35
+ var xpad = 15;
36
+ var ypad = 15;
37
+ function samegene(arg) {
38
+ const isoform = arg.isoform;
39
+ if (!isoform) {
40
+ arg.holder.text(".event missing");
41
+ return;
42
+ }
43
+ if (!arg.ongene) {
44
+ holder.text(".ongene missing");
45
+ return;
46
+ }
47
+ let exonleft, exonright, exonleftin, exonrightin, intronleft, intronright, leftout, rightout;
48
+ if (arg.ongene.exonleft) {
49
+ const a = arg.ongene.exonleft.filter((i) => i.isoform == isoform)[0];
50
+ if (arg.reverse) exonright = a;
51
+ else exonleft = a;
52
+ }
53
+ if (arg.ongene.exonright) {
54
+ const a = arg.ongene.exonright.filter((i) => i.isoform == isoform)[0];
55
+ if (arg.reverse) exonleft = a;
56
+ else exonright = a;
57
+ }
58
+ if (arg.ongene.exonleftin) {
59
+ const a = arg.ongene.exonleftin.filter((i) => i.isoform == isoform)[0];
60
+ if (arg.reverse) exonrightin = a;
61
+ else exonleftin = a;
62
+ }
63
+ if (arg.ongene.exonrightin) {
64
+ const a = arg.ongene.exonrightin.filter((i) => i.isoform == isoform)[0];
65
+ if (arg.reverse) exonleftin = a;
66
+ else exonrightin = a;
67
+ }
68
+ if (arg.ongene.intronleft) {
69
+ const a = arg.ongene.intronleft.filter((i) => i.isoform == isoform)[0];
70
+ if (arg.reverse) intronright = a;
71
+ else intronleft = a;
72
+ }
73
+ if (arg.ongene.intronright) {
74
+ const a = arg.ongene.intronright.filter((i) => i.isoform == isoform)[0];
75
+ if (arg.reverse) intronleft = a;
76
+ else intronright = a;
77
+ }
78
+ if (arg.ongene.leftout) {
79
+ const a = arg.ongene.leftout.filter((i) => i.isoform == isoform)[0];
80
+ if (arg.reverse) rightout = a;
81
+ else leftout = a;
82
+ }
83
+ if (arg.ongene.rightout) {
84
+ const a = arg.ongene.rightout.filter((i) => i.isoform == isoform)[0];
85
+ if (arg.reverse) leftout = a;
86
+ else rightout = a;
87
+ }
88
+ const svg = arg.holder.append("svg").attr("width", 1).attr("height", 1);
89
+ if (exonleft) {
90
+ if (exonright) {
91
+ exonleft_exonright(exonleft, exonright, svg);
92
+ } else if (exonrightin) {
93
+ exonleft_exonrightin(exonleft, exonrightin, svg);
94
+ } else if (intronright) {
95
+ exonleft_intronright(exonleft, intronright, svg);
96
+ } else {
97
+ exonleft_rightout(exonleft, svg);
98
+ }
99
+ } else if (exonleftin) {
100
+ if (exonright) {
101
+ exonleftin_exonright(exonleftin, exonright, svg);
102
+ } else if (exonrightin) {
103
+ exonleftin_exonrightin(exonleftin, exonrightin, svg);
104
+ } else if (intronright) {
105
+ exonleftin_intronright(exonleftin, intronright, svg);
106
+ } else {
107
+ exonleftin_rightout(exonleftin, svg);
108
+ }
109
+ } else if (intronleft) {
110
+ if (exonright) {
111
+ intronleft_exonright(intronleft, exonright, svg);
112
+ } else if (exonrightin) {
113
+ intronleft_exonrightin(intronleft, exonrightin, svg);
114
+ } else if (intronright) {
115
+ intronleft_intronright(intronleft, intronright, svg);
116
+ } else {
117
+ intronleft_rightout(intronleft, svg);
118
+ }
119
+ } else {
120
+ if (exonright) {
121
+ leftout_exonright(exonright, svg);
122
+ } else if (exonrightin) {
123
+ leftout_exonrightin(exonrightin, svg);
124
+ } else if (intronright) {
125
+ leftout_intronright(intronright, svg);
126
+ }
127
+ }
128
+ }
129
+ function differentgenes(arg) {
130
+ const svg = arg.holder.append("svg");
131
+ const g = svg.append("g").attr("transform", "translate(" + xpad + "," + ypad + ")");
132
+ let x1 = 0, x2 = 0;
133
+ let exonleft, exonleftin, intronleft;
134
+ if (arg.ongene.exonleft) {
135
+ exonleft = arg.ongene.exonleft[0];
136
+ } else if (arg.ongene.exonleftin) {
137
+ exonleftin = arg.ongene.exonleftin[0];
138
+ } else if (arg.ongene.intronleft) {
139
+ intronleft = arg.ongene.intronleft[0];
140
+ }
141
+ let x = 0;
142
+ g.append("text").text(exonleft ? exonleft.gene : exonleftin ? exonleftin.gene : intronleft ? intronleft.gene : "Left gene").attr("x", 0).attr("y", junctionheight + exonheight / 2).attr("dominant-baseline", "central").attr("font-size", fontsize).attr("font-family", font).each(function() {
143
+ x = this.getBBox().width;
144
+ });
145
+ x += 5;
146
+ if (exonleft) {
147
+ const w = renderRightExon(x, exonleft.exonidx, g);
148
+ x += w;
149
+ x1 = x;
150
+ } else if (exonleftin) {
151
+ const w = renderRightExon(x, exonleftin.exonidx, g);
152
+ x1 = x + w / 2;
153
+ x += w;
154
+ } else if (intronleft) {
155
+ const w1 = renderRightExon(x, intronleft.intronidx, g);
156
+ renderIntron(g, x + w1, x + w1 + intronwidth);
157
+ const w2 = renderRightExon(x + w1 + intronwidth, intronleft.intronidx + 1, g);
158
+ x += w1;
159
+ x1 = x + intronwidth / 2;
160
+ x += intronwidth + w2;
161
+ }
162
+ x += 30;
163
+ let exonright, exonrightin, intronright;
164
+ if (arg.ongene.exonright) {
165
+ exonright = arg.ongene.exonright[0];
166
+ } else if (arg.ongene.exonrightin) {
167
+ exonrightin = arg.ongene.exonrightin[0];
168
+ } else if (arg.ongene.intronright) {
169
+ intronright = arg.ongene.intronright[0];
170
+ }
171
+ if (exonright) {
172
+ const w = renderRightExon(x, exonright.exonidx, g);
173
+ x2 = x;
174
+ x += w;
175
+ } else if (exonrightin) {
176
+ const w = renderRightExon(x, exonrightin.exonidx, g);
177
+ x2 = x + w / 2;
178
+ x += w;
179
+ } else if (intronright) {
180
+ const w1 = renderRightExon(x, intronright.intronidx, g);
181
+ renderIntron(g, x + w1, x + w1 + intronwidth);
182
+ const w2 = renderRightExon(x + w1 + intronwidth, intronright.intronidx + 1, g);
183
+ x += w1;
184
+ x2 = x + intronwidth / 2;
185
+ x += intronwidth + w2;
186
+ }
187
+ x += 5;
188
+ g.append("text").text(exonright ? exonright.gene : exonrightin ? exonrightin.gene : intronright ? intronright.gene : "Right gene").attr("x", x).attr("y", junctionheight + exonheight / 2).attr("dominant-baseline", "central").attr("font-size", fontsize).attr("font-family", font).each(function() {
189
+ x += this.getBBox().width;
190
+ });
191
+ renderJunction(g, x1, x2, intronleft, intronright);
192
+ svg.attr("width", xpad * 2 + x).attr("height", junctionheight + exonheight + ypad * 2);
193
+ }
194
+ function exonleft_exonright(l, r, svg) {
195
+ const g = svg.append("g").attr("transform", "translate(" + xpad + "," + ypad + ")");
196
+ const isnormaljunction = r.exonidx - l.exonidx == 1;
197
+ const x1 = renderLeftExon(l.exonidx, g);
198
+ let x2 = x1;
199
+ x2 += renderMidExons(x2, l.exonidx, r.exonidx, g);
200
+ if (!isnormaljunction) {
201
+ renderIntron(g, x2, x2 + intronwidth);
202
+ }
203
+ x2 += intronwidth;
204
+ const rightboxw = renderRightExon(x2, r.exonidx, g);
205
+ renderJunction(g, x1, x2, false, false, true);
206
+ svg.attr("width", xpad * 2 + x2 + rightboxw).attr("height", ypad * 2 + junctionheight + exonheight);
207
+ }
208
+ function exonleft_exonrightin(l, r, svg) {
209
+ const g = svg.append("g").attr("transform", "translate(" + xpad + "," + ypad + ")");
210
+ const x1 = renderLeftExon(l.exonidx, g);
211
+ let x2 = x1;
212
+ x2 += renderMidExons(x2, l.exonidx, r.exonidx, g);
213
+ renderIntron(g, x2, x2 + intronwidth);
214
+ x2 += intronwidth;
215
+ const rightboxw = renderRightExon(x2, r.exonidx, g);
216
+ x2 += rightboxw / 2;
217
+ renderJunction(g, x1, x2);
218
+ svg.attr("width", xpad * 2 + x2 + rightboxw / 2).attr("height", ypad * 2 + junctionheight + exonheight);
219
+ }
220
+ function exonleft_intronright(l, r, svg) {
221
+ const g = svg.append("g").attr("transform", "translate(" + xpad + "," + ypad + ")");
222
+ const x1 = renderLeftExon(l.exonidx, g);
223
+ let x2 = x1;
224
+ x2 += renderMidExons(x2, l.exonidx, r.intronidx + 1, g);
225
+ renderIntron(g, x2, x2 + intronwidth);
226
+ x2 += intronwidth / 2;
227
+ const rightboxw = renderRightExon(x2 + intronwidth / 2, r.intronidx + 1, g);
228
+ renderJunction(g, x1, x2, false, true);
229
+ svg.attr("width", xpad * 2 + x2 + intronwidth / 2 + rightboxw).attr("height", ypad * 2 + junctionheight + exonheight);
230
+ }
231
+ function exonleft_rightout(l, svg) {
232
+ const g = svg.append("g").attr("transform", "translate(" + xpad + "," + ypad + ")");
233
+ const x1 = renderLeftExon(l.exonidx, g);
234
+ const x2 = x1 + intronwidth;
235
+ g.append("text").text("OUT").attr("x", x2 + 5).attr("y", junctionheight + exonheight / 2).attr("fill", junctionBcolor).attr("dominant-baseline", "central").attr("font-size", fontsize).attr("font-family", font);
236
+ renderJunction(g, x1, x2);
237
+ svg.attr("width", xpad * 2 + x2 + 40).attr("height", ypad * 2 + junctionheight + exonheight);
238
+ }
239
+ function exonleftin_exonright(l, r, svg) {
240
+ const g = svg.append("g").attr("transform", "translate(" + xpad + "," + ypad + ")");
241
+ const leftboxw = renderLeftExon(l.exonidx, g);
242
+ const x1 = leftboxw / 2;
243
+ let x2 = leftboxw;
244
+ x2 += renderMidExons(x2, l.exonidx, r.exonidx, g);
245
+ renderIntron(g, x2, x2 + intronwidth);
246
+ x2 += intronwidth;
247
+ const rightboxw = renderRightExon(x2, r.exonidx, g);
248
+ renderJunction(g, x1, x2);
249
+ svg.attr("width", xpad * 2 + x2 + rightboxw).attr("height", ypad * 2 + junctionheight + exonheight);
250
+ }
251
+ function exonleftin_exonrightin(l, r, svg) {
252
+ const g = svg.append("g").attr("transform", "translate(" + xpad + "," + ypad + ")");
253
+ const leftboxw = renderLeftExon(l.exonidx, g);
254
+ if (l.exonidx == r.exonidx) {
255
+ const x12 = leftboxw / 3;
256
+ const x22 = leftboxw * 2 / 3;
257
+ g.append("path").attr("d", "M" + x12 + "," + junctionheight + "L" + (x12 + x22) / 2 + ",0L" + x22 + "," + junctionheight).attr("stroke", junctionBcolor).attr("fill", "none");
258
+ svg.attr("width", xpad * 2 + leftboxw).attr("height", ypad * 2 + junctionheight * 2 + exonheight);
259
+ return;
260
+ }
261
+ const x1 = leftboxw / 2;
262
+ let x2 = leftboxw;
263
+ x2 += renderMidExons(x2, l.exonidx, r.exonidx, g);
264
+ renderIntron(g, x2, x2 + intronwidth);
265
+ x2 += intronwidth;
266
+ const rightboxw = renderRightExon(x2, r.exonidx, g);
267
+ x2 += rightboxw / 2;
268
+ renderJunction(g, x1, x2);
269
+ svg.attr("width", xpad * 2 + x2 + rightboxw / 2).attr("height", ypad * 2 + junctionheight + exonheight);
270
+ }
271
+ function exonleftin_intronright(l, r, svg) {
272
+ const g = svg.append("g").attr("transform", "translate(" + xpad + "," + ypad + ")");
273
+ const leftboxw = renderLeftExon(l.exonidx, g);
274
+ const x1 = leftboxw / 2;
275
+ let x2 = leftboxw;
276
+ x2 += renderMidExons(x2, l.exonidx, r.intronidx + 1, g);
277
+ renderIntron(g, x2, x2 + intronwidth);
278
+ x2 += intronwidth / 2;
279
+ const rightboxw = renderRightExon(x2 + intronwidth / 2, r.intronidx + 1, g);
280
+ renderJunction(g, x1, x2, false, true);
281
+ svg.attr("width", xpad * 2 + x2 + intronwidth / 2 + rightboxw).attr("height", ypad * 2 + junctionheight + exonheight);
282
+ }
283
+ function exonleftin_rightout(l, svg) {
284
+ const g = svg.append("g").attr("transform", "translate(" + xpad + "," + ypad + ")");
285
+ const leftboxw = renderLeftExon(l.exonidx, g);
286
+ const x1 = leftboxw / 2;
287
+ let x2 = leftboxw + intronwidth;
288
+ g.append("text").text("OUT").attr("x", x2 + 5).attr("y", junctionheight + exonheight / 2).attr("fill", junctionBcolor).attr("dominant-baseline", "central").attr("font-size", fontsize).attr("font-family", font);
289
+ renderJunction(g, x1, x2);
290
+ svg.attr("width", xpad * 2 + x2 + 40).attr("height", ypad * 2 + junctionheight + exonheight);
291
+ }
292
+ function intronleft_exonright(l, r, svg) {
293
+ const g = svg.append("g").attr("transform", "translate(" + xpad + "," + ypad + ")");
294
+ const leftboxw = renderLeftExon(l.intronidx, g);
295
+ const x1 = leftboxw + intronwidth / 2;
296
+ let x2 = leftboxw + intronwidth;
297
+ renderIntron(g, leftboxw, x2);
298
+ x2 += renderMidExons(x2, l.intronidx, r.exonidx, g, true);
299
+ const rightboxw = renderRightExon(x2, r.exonidx, g);
300
+ renderJunction(g, x1, x2, true);
301
+ svg.attr("width", xpad * 2 + x2 + rightboxw).attr("height", ypad * 2 + junctionheight + exonheight);
302
+ }
303
+ function intronleft_exonrightin(l, r, svg) {
304
+ const g = svg.append("g").attr("transform", "translate(" + xpad + "," + ypad + ")");
305
+ const leftboxw = renderLeftExon(l.intronidx, g);
306
+ const x1 = leftboxw + intronwidth / 2;
307
+ let x2 = leftboxw + intronwidth;
308
+ renderIntron(g, leftboxw, x2);
309
+ x2 += renderMidExons(x2, l.intronidx, r.exonidx, g, true);
310
+ const rightboxw = renderRightExon(x2, r.exonidx, g);
311
+ x2 += rightboxw / 2;
312
+ renderJunction(g, x1, x2, true);
313
+ svg.attr("width", xpad * 2 + x2 + rightboxw / 2).attr("height", ypad * 2 + junctionheight + exonheight);
314
+ }
315
+ function intronleft_intronright(l, r, svg) {
316
+ const g = svg.append("g").attr("transform", "translate(" + xpad + "," + ypad + ")");
317
+ const leftboxw = renderLeftExon(l.intronidx, g);
318
+ if (l.intronidx == r.intronidx) {
319
+ renderIntron(g, leftboxw, leftboxw + 30);
320
+ const x12 = leftboxw + 10;
321
+ const x22 = leftboxw + 20;
322
+ renderJunction(g, x12, x22, true, true);
323
+ const rightboxw2 = renderRightExon(x22 + 10, r.intronidx + 1, g);
324
+ svg.attr("width", xpad * 2 + leftboxw + 30 + rightboxw2).attr("height", ypad * 2 + junctionheight + exonheight);
325
+ return;
326
+ }
327
+ const x1 = leftboxw + intronwidth / 2;
328
+ let x2 = leftboxw + intronwidth;
329
+ renderIntron(g, leftboxw, x2);
330
+ x2 += renderMidExons(x2, l.intronidx, r.intronidx + 1, g, true);
331
+ renderIntron(g, x2, x2 + intronwidth);
332
+ x2 += intronwidth / 2;
333
+ const rightboxw = renderRightExon(x2 + intronwidth / 2, r.intronidx + 1, g);
334
+ renderJunction(g, x1, x2, true, true);
335
+ svg.attr("width", xpad * 2 + x2 + intronwidth / 2 + rightboxw).attr("height", ypad * 2 + junctionheight + exonheight);
336
+ }
337
+ function intronleft_rightout(l, svg) {
338
+ const g = svg.append("g").attr("transform", "translate(" + xpad + "," + ypad + ")");
339
+ const leftboxw = renderLeftExon(l.intronidx, g);
340
+ const x1 = leftboxw + intronwidth / 2;
341
+ let x2 = leftboxw + intronwidth;
342
+ renderIntron(g, leftboxw, x2);
343
+ const rightboxw = renderRightExon(x2, l.intronidx + 1, g);
344
+ x2 += rightboxw + 10;
345
+ g.append("text").text("OUT").attr("x", x2).attr("y", junctionheight + exonheight / 2).attr("fill", junctionBcolor).attr("dominant-baseline", "central").attr("font-size", fontsize).attr("font-family", font);
346
+ renderJunction(g, x1, x2, true);
347
+ svg.attr("width", xpad * 2 + x2 + 30).attr("height", ypad * 2 + junctionheight + exonheight);
348
+ }
349
+ function leftout_exonright(r, svg) {
350
+ const g = svg.append("g").attr("transform", "translate(" + xpad + "," + ypad + ")");
351
+ let leftboxw;
352
+ g.append("text").text("OUT").attr("x", 0).attr("y", junctionheight + exonheight / 2).attr("fill", junctionBcolor).attr("dominant-baseline", "central").attr("font-size", fontsize).attr("font-family", font).each(function() {
353
+ leftboxw = this.getBBox().width;
354
+ });
355
+ const x1 = leftboxw + 5;
356
+ const x2 = x1 + intronwidth;
357
+ const rightboxw = renderRightExon(x2, r.exonidx, g);
358
+ renderJunction(g, x1, x2);
359
+ svg.attr("width", xpad * 2 + x2 + rightboxw).attr("height", ypad * 2 + junctionheight + exonheight);
360
+ }
361
+ function leftout_exonrightin(r, svg) {
362
+ const g = svg.append("g").attr("transform", "translate(" + xpad + "," + ypad + ")");
363
+ let leftboxw;
364
+ g.append("text").text("OUT").attr("x", 0).attr("y", junctionheight + exonheight / 2).attr("fill", junctionBcolor).attr("dominant-baseline", "central").attr("font-size", fontsize).attr("font-family", font).each(function() {
365
+ leftboxw = this.getBBox().width;
366
+ });
367
+ const x1 = leftboxw + 5;
368
+ const rightboxw = renderRightExon(x1 + intronwidth, r.exonidx, g);
369
+ const x2 = x1 + intronwidth + rightboxw / 2;
370
+ renderJunction(g, x1, x2);
371
+ svg.attr("width", xpad * 2 + x2 + rightboxw / 2).attr("height", ypad * 2 + junctionheight + exonheight);
372
+ }
373
+ function leftout_intronright(r, svg) {
374
+ const g = svg.append("g").attr("transform", "translate(" + xpad + "," + ypad + ")");
375
+ let leftboxw;
376
+ g.append("text").text("OUT").attr("x", 0).attr("y", junctionheight + exonheight / 2).attr("fill", junctionBcolor).attr("dominant-baseline", "central").attr("font-size", fontsize).attr("font-family", font).each(function() {
377
+ leftboxw = this.getBBox().width;
378
+ });
379
+ const x1 = leftboxw + 5;
380
+ const exon1w = renderRightExon(x1 + 30, r.intronidx, g);
381
+ renderIntron(g, x1 + 30 + exon1w, x1 + 30 + exon1w + intronwidth);
382
+ const x2 = x1 + 30 + exon1w + intronwidth / 2;
383
+ const exon2w = renderRightExon(x1 + 30 + exon1w + intronwidth, r.intronidx + 1, g);
384
+ renderJunction(g, x1, x2, false, true);
385
+ svg.attr("width", xpad * 2 + x1 + 30 + exon1w + intronwidth + exon2w).attr("height", ypad * 2 + junctionheight + exonheight);
386
+ }
387
+ function renderIntron(g, x1, x2) {
388
+ g.append("line").attr("x1", x1).attr("y1", junctionheight + exonheight / 2).attr("x2", x2).attr("y2", junctionheight + exonheight / 2).attr("stroke", exoncolor).attr("shape-rendering", "crispEdges");
389
+ }
390
+ function renderJunction(g, x1, x2, x1atintron, x2atintron, isnormal) {
391
+ g.append("path").attr(
392
+ "d",
393
+ "M" + x1 + "," + (junctionheight + (x1atintron ? exonheight / 2 : 0)) + "L" + (x1 + x2) / 2 + ",0L" + x2 + "," + (junctionheight + (x2atintron ? exonheight / 2 : 0))
394
+ ).attr("stroke", isnormal ? exoncolor : junctionBcolor).attr("fill", "none");
395
+ }
396
+ function renderLeftExon(exonidx, g) {
397
+ const text = "e" + (exonidx + 1);
398
+ let textw;
399
+ g.append("text").text(text).attr("font-size", fontsize).attr("font-family", font).each(function() {
400
+ textw = this.getBBox().width;
401
+ }).remove();
402
+ const boxw = exonxpad * 2 + textw;
403
+ g.append("rect").attr("fill", exoncolor).attr("stroke", exoncolor).attr("x", 0).attr("y", junctionheight).attr("width", boxw).attr("height", exonheight).attr("shape-rendering", "crispEdges");
404
+ g.append("text").text(text).attr("text-anchor", "middle").attr("x", boxw / 2).attr("y", junctionheight + exonheight / 2).attr("fill", "white").attr("dominant-baseline", "central").attr("font-size", fontsize).attr("font-family", font);
405
+ return boxw;
406
+ }
407
+ function renderRightExon(x, exonidx, g) {
408
+ let text;
409
+ if (Number.isInteger(exonidx)) {
410
+ text = "e" + (exonidx + 1);
411
+ } else {
412
+ text = text;
413
+ }
414
+ let textw;
415
+ g.append("text").text(text).attr("font-size", fontsize).attr("font-family", font).each(function() {
416
+ textw = this.getBBox().width;
417
+ }).remove();
418
+ const boxw = exonxpad * 2 + textw;
419
+ g.append("rect").attr("fill", exoncolor).attr("stroke", exoncolor).attr("x", x).attr("y", junctionheight).attr("width", boxw).attr("height", exonheight).attr("shape-rendering", "crispEdges");
420
+ g.append("text").text(text).attr("text-anchor", "middle").attr("x", x + boxw / 2).attr("y", junctionheight + exonheight / 2).attr("fill", "white").attr("dominant-baseline", "central").attr("font-size", fontsize).attr("font-family", font);
421
+ return boxw;
422
+ }
423
+ function width4middleexons(exonnum) {
424
+ if (exonnum < 3) return 12;
425
+ if (exonnum < 6) return 7;
426
+ return 4;
427
+ }
428
+ function renderMidExons(x, lidx, ridx, g, showintronafterexon) {
429
+ const midexonnum = ridx - 1 - lidx;
430
+ if (midexonnum == 0) return 0;
431
+ const smallwidth = width4middleexons(midexonnum);
432
+ let w = 0;
433
+ for (let i = lidx + 1; i < ridx; i++) {
434
+ if (!showintronafterexon) {
435
+ g.append("line").attr("x1", x + w).attr("y1", junctionheight + exonheight / 2).attr("x2", x + w + smallwidth).attr("y2", junctionheight + exonheight / 2).attr("stroke", exoncolor).attr("shape-rendering", "crispEdges");
436
+ w += smallwidth;
437
+ }
438
+ g.append("rect").attr("fill", exoncolor).attr("stroke", exoncolor).attr("x", x + w).attr("y", junctionheight).attr("width", smallwidth).attr("height", exonheight).attr("shape-rendering", "crispEdges");
439
+ w += smallwidth;
440
+ if (showintronafterexon) {
441
+ g.append("line").attr("x1", x + w).attr("y1", junctionheight + exonheight / 2).attr("x2", x + w + smallwidth).attr("y2", junctionheight + exonheight / 2).attr("stroke", exoncolor).attr("shape-rendering", "crispEdges");
442
+ w += smallwidth;
443
+ }
444
+ }
445
+ return w;
446
+ }
447
+ export {
448
+ differentgenes,
449
+ samegene
450
+ };
451
+ //# sourceMappingURL=spliceevent.noeventdiagram-SUBU5BLZ.js.map
@@ -0,0 +1,29 @@
1
+ import {
2
+ SearchHandler
3
+ } from "./chunk-VDXHBYZS.js";
4
+ import "./chunk-U45YALDI.js";
5
+ import "./chunk-HJ6L54YS.js";
6
+ import "./chunk-KZXFNO75.js";
7
+ import "./chunk-CNFTQSNE.js";
8
+ import "./chunk-RIHO7ZD5.js";
9
+ import "./chunk-TVJOSRCH.js";
10
+ import "./chunk-3CIL7KH7.js";
11
+ import "./chunk-T4XPCSLP.js";
12
+ import "./chunk-KBTFT76L.js";
13
+ import "./chunk-W5J3LTYS.js";
14
+ import "./chunk-MHWYRNGA.js";
15
+ import "./chunk-JHLF2ZC2.js";
16
+ import "./chunk-WJLRU5OF.js";
17
+ import "./chunk-HBNB5TRH.js";
18
+ import "./chunk-PF4DSFDR.js";
19
+ import "./chunk-4OLM3KSB.js";
20
+ import "./chunk-PWYMHUXY.js";
21
+ import "./chunk-TLT4YIG3.js";
22
+ import "./chunk-5R63Q5KH.js";
23
+ import "./chunk-I6Y4O3RR.js";
24
+ import "./chunk-Q5RDQNIT.js";
25
+ import "./chunk-HS5PO5ZQ.js";
26
+ export {
27
+ SearchHandler
28
+ };
29
+ //# sourceMappingURL=ssGSEA-V4W3E6MF.js.map
@@ -0,0 +1,79 @@
1
+ import {
2
+ SearchHandler
3
+ } from "./chunk-VDXHBYZS.js";
4
+ import {
5
+ require_tape
6
+ } from "./chunk-PJYCTAMC.js";
7
+ import "./chunk-U45YALDI.js";
8
+ import "./chunk-HJ6L54YS.js";
9
+ import "./chunk-KZXFNO75.js";
10
+ import "./chunk-CNFTQSNE.js";
11
+ import "./chunk-RIHO7ZD5.js";
12
+ import "./chunk-TVJOSRCH.js";
13
+ import "./chunk-3CIL7KH7.js";
14
+ import "./chunk-T4XPCSLP.js";
15
+ import "./chunk-KBTFT76L.js";
16
+ import "./chunk-W5J3LTYS.js";
17
+ import "./chunk-MHWYRNGA.js";
18
+ import "./chunk-JHLF2ZC2.js";
19
+ import "./chunk-WJLRU5OF.js";
20
+ import "./chunk-HBNB5TRH.js";
21
+ import "./chunk-PF4DSFDR.js";
22
+ import "./chunk-4OLM3KSB.js";
23
+ import "./chunk-PWYMHUXY.js";
24
+ import "./chunk-TLT4YIG3.js";
25
+ import "./chunk-5R63Q5KH.js";
26
+ import {
27
+ select_default
28
+ } from "./chunk-I6Y4O3RR.js";
29
+ import "./chunk-Q5RDQNIT.js";
30
+ import {
31
+ __toESM
32
+ } from "./chunk-HS5PO5ZQ.js";
33
+
34
+ // termdb/handlers/test/ssGSEA.unit.spec.ts
35
+ var import_tape = __toESM(require_tape(), 1);
36
+ function getHolder() {
37
+ return select_default("body").append("div");
38
+ }
39
+ (0, import_tape.default)("\n", function(test) {
40
+ test.comment("-***- termdb/handlers/ssGSEA -***-");
41
+ test.end();
42
+ });
43
+ (0, import_tape.default)("init() should throw when genomeObj.termdbs is missing", async (test) => {
44
+ const handler = new SearchHandler();
45
+ const holder = getHolder();
46
+ try {
47
+ await handler.init({
48
+ holder,
49
+ callback: () => {
50
+ },
51
+ app: {},
52
+ genomeObj: { name: "hg38" }
53
+ });
54
+ test.fail("Should throw when genesetDbName is missing");
55
+ } catch (e) {
56
+ test.match(String(e), /genesetDbName missing/, "Should throw expected error message");
57
+ }
58
+ if (test["_ok"]) holder.remove();
59
+ test.end();
60
+ });
61
+ (0, import_tape.default)("init() should throw when genomeObj.termdbs is empty", async (test) => {
62
+ const handler = new SearchHandler();
63
+ const holder = getHolder();
64
+ try {
65
+ await handler.init({
66
+ holder,
67
+ callback: () => {
68
+ },
69
+ app: {},
70
+ genomeObj: { name: "hg38", termdbs: {} }
71
+ });
72
+ test.fail("Should throw when no databases are available");
73
+ } catch (e) {
74
+ test.match(String(e), /genesetDbName missing/, "Should throw expected error message for empty termdbs");
75
+ }
76
+ if (test["_ok"]) holder.remove();
77
+ test.end();
78
+ });
79
+ //# sourceMappingURL=ssGSEA.unit.spec-DYMT2CCB.js.map
@@ -0,0 +1,112 @@
1
+ import {
2
+ PlotBase
3
+ } from "./chunk-U45YALDI.js";
4
+ import "./chunk-HJ6L54YS.js";
5
+ import "./chunk-KZXFNO75.js";
6
+ import "./chunk-CNFTQSNE.js";
7
+ import "./chunk-RIHO7ZD5.js";
8
+ import "./chunk-TVJOSRCH.js";
9
+ import "./chunk-3CIL7KH7.js";
10
+ import "./chunk-T4XPCSLP.js";
11
+ import "./chunk-KBTFT76L.js";
12
+ import "./chunk-W5J3LTYS.js";
13
+ import "./chunk-MHWYRNGA.js";
14
+ import "./chunk-JHLF2ZC2.js";
15
+ import "./chunk-WJLRU5OF.js";
16
+ import {
17
+ getCompInit
18
+ } from "./chunk-HBNB5TRH.js";
19
+ import "./chunk-PF4DSFDR.js";
20
+ import "./chunk-4OLM3KSB.js";
21
+ import "./chunk-PWYMHUXY.js";
22
+ import "./chunk-TLT4YIG3.js";
23
+ import "./chunk-5R63Q5KH.js";
24
+ import "./chunk-I6Y4O3RR.js";
25
+ import "./chunk-Q5RDQNIT.js";
26
+ import "./chunk-HS5PO5ZQ.js";
27
+
28
+ // plots/stattable.js
29
+ var TdbStatTable = class _TdbStatTable extends PlotBase {
30
+ static type = "stattable";
31
+ constructor(opts, api) {
32
+ super(opts, api);
33
+ this.type = _TdbStatTable.type;
34
+ }
35
+ async init() {
36
+ this.dom = {
37
+ div: this.opts.holder.append("div").style("margin", "10px")
38
+ };
39
+ setRenderers(this);
40
+ }
41
+ getState(appState) {
42
+ const config = appState.plots.find((p) => p.id === this.id);
43
+ if (!config) {
44
+ throw `No plot with id='${this.id}' found. Did you set this.id before this.api = getComponentApi(this)?`;
45
+ }
46
+ return {
47
+ activeCohort: appState.activeCohort,
48
+ termfilter: appState.termfilter,
49
+ config: {
50
+ term: config.term,
51
+ term0: config.term0,
52
+ term2: config.term2,
53
+ settings: {
54
+ common: config.settings.common,
55
+ barchart: config.settings.barchart
56
+ }
57
+ },
58
+ filter: appState.termfilter.filter
59
+ };
60
+ }
61
+ async main() {
62
+ try {
63
+ this.config = structuredClone(this.state.config);
64
+ if (this.state.isVisible) {
65
+ const reqOpts = this.getDataRequestOpts();
66
+ const data = await this.vocabApi.getNestedChartSeriesData(reqOpts);
67
+ this.app.vocabApi.syncTermData(this.state.config, data);
68
+ }
69
+ if (!this.state.isVisible || !this.data || !this.data.boxplot) {
70
+ this.dom.div.style("display", "none");
71
+ return;
72
+ }
73
+ this.render(this.data);
74
+ } catch (e) {
75
+ throw e;
76
+ }
77
+ }
78
+ // creates an opts object for the vocabApi.getNestedChartsData()
79
+ getDataRequestOpts() {
80
+ const c = this.config;
81
+ const opts = { term: c.term, filter: this.state.termfilter.filter };
82
+ if (c.term2) opts.term2 = c.term2;
83
+ if (c.term0) opts.term0 = c.term0;
84
+ return opts;
85
+ }
86
+ };
87
+ function setRenderers(self) {
88
+ self.render = function(data) {
89
+ self.dom.div.style("display", "block").selectAll("*").remove();
90
+ let exposed_data = "";
91
+ const sd = data.boxplot.sd ? " (" + data.boxplot.sd.toFixed(2) + ") " : "";
92
+ let rows = "";
93
+ if (Number.isFinite(data.boxplot.min)) {
94
+ rows += "<tr><td>Minimum</td><td>" + data.boxplot.min.toFixed(2) + "</td></tr>";
95
+ }
96
+ if (Number.isFinite(data.boxplot.max)) {
97
+ rows += "<tr><td>Maximum</td><td>" + data.boxplot.max.toFixed(2) + "</td></tr>";
98
+ }
99
+ rows += "<tr><td>Mean (SD)</td><td>" + data.boxplot.mean.toFixed(2) + sd + "</td></tr>";
100
+ if ("p50" in data.boxplot) {
101
+ rows += "<tr><td>Median (IQR)</td><td>" + data.boxplot.p50.toFixed(2) + " (" + data.boxplot.iqr.toFixed(2) + ") </td></tr><tr><td>5th Percentile</td><td>" + data.boxplot.p05.toFixed(2) + "</td></tr><tr><td>25th Percentile</td><td>" + data.boxplot.p25.toFixed(2) + "</td></tr><tr><td>75th Percentile</td><td>" + data.boxplot.p75.toFixed(2) + "</td></tr><tr><td>95th Percentile</td><td>" + data.boxplot.p95.toFixed(2) + "</td></tr>";
102
+ }
103
+ self.dom.div.html("<table><tr><th></th><th>Value</th></tr>" + exposed_data + rows + "</table>");
104
+ self.dom.div.selectAll("td, th, table").style("border", "1px solid black").style("padding", "0").style("border-collapse", "collapse");
105
+ self.dom.div.selectAll("th, td").style("padding", "2px 10px");
106
+ };
107
+ }
108
+ var statTableInit = getCompInit(TdbStatTable);
109
+ export {
110
+ statTableInit
111
+ };
112
+ //# sourceMappingURL=stattable-DJCYOA6Y.js.map