@sjcrh/proteinpaint-client 2.208.0 → 2.210.0
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/dist/2dmaf-43QBND66.js +1367 -0
- package/dist/AggMatrixInput-X7NGFUHH.js +406 -0
- package/dist/AggregateMatrix-M4HRI4PX.js +41 -0
- package/dist/AppHeader-QBRQN6PM.js +830 -0
- package/dist/BoxPlot-V6SPSEQ2.js +1211 -0
- package/dist/CorrelationVolcano-UFPCYC77.js +617 -0
- package/dist/Cuminc-KXGXGLKZ.js +1219 -0
- package/dist/DE-K2YXHOOW.js +89 -0
- package/dist/DEinput-O6LBFAAH.js +501 -0
- package/dist/DEinput-O6LBFAAH.js.map +7 -0
- package/dist/DM-C7VN3RWB.js +90 -0
- package/dist/DifferentialAnalysis-A2BU4WB3.js +239 -0
- package/dist/DifferentialAnalysis-A2BU4WB3.js.map +7 -0
- package/dist/Disco-HECQVKXG.js +3389 -0
- package/dist/Disco.UI-XF2GEKRW.js +243 -0
- package/dist/DmrPlot-TVXVXOHL.js +362 -0
- package/dist/DmrPlot-TVXVXOHL.js.map +7 -0
- package/dist/GB-66ZGJ5ST.js +1428 -0
- package/dist/GB-66ZGJ5ST.js.map +7 -0
- package/dist/GSEA-Z4YPI4HY.js +875 -0
- package/dist/GSEA-Z4YPI4HY.js.map +7 -0
- package/dist/GeneExpInput-VBIZZV27.js +42 -0
- package/dist/Geomap-UIIOLRFA.js +84 -0
- package/dist/HicApp-73ESVNBA.js +2245 -0
- package/dist/IDCViewer-RBYN5A4P.js +10812 -0
- package/dist/NumBinaryEditor-DJLSNSLE.js +279 -0
- package/dist/NumBinaryEditor.unit.spec-LCJHL3XM.js +312 -0
- package/dist/NumContEditor-SVLDJ2ML.js +105 -0
- package/dist/NumContEditor.unit.spec-JDMSK4HY.js +164 -0
- package/dist/NumCustomBinEditor-BI63AH3R.js +33 -0
- package/dist/NumCustomBinEditor.unit.spec-5433G7Y2.js +397 -0
- package/dist/NumDiscreteEditor-LEZTGXAV.js +170 -0
- package/dist/NumDiscreteEditor.unit.spec-5OEORHJ4.js +233 -0
- package/dist/NumRegularBinEditor-EXWHIWPM.js +33 -0
- package/dist/NumRegularBinEditor.unit.spec-QY25Z2TT.js +278 -0
- package/dist/NumSplineEditor-XPPMYYAD.js +210 -0
- package/dist/NumSplineEditor.unit.spec-GOGBKWMN.js +224 -0
- package/dist/NumericDensity-RKY2IQ72.js +33 -0
- package/dist/NumericDensity.unit.spec-5ZM6ICXM.js +418 -0
- package/dist/NumericHandler-FXF3M5M3.js +34 -0
- package/dist/NumericHandler.unit.spec-M2OQTBJX.js +214 -0
- package/dist/ProteomeInput-TMZ3THRL.js +388 -0
- package/dist/Regression-GQGAATHG.js +1416 -0
- package/dist/Regression-GQGAATHG.js.map +7 -0
- package/dist/RunChart2-7GNDWRKC.js +749 -0
- package/dist/SC-R2I2EMHA.js +1183 -0
- package/dist/SC-R2I2EMHA.js.map +7 -0
- package/dist/Violin-GKKEB55L.js +1081 -0
- package/dist/Violin-GKKEB55L.js.map +7 -0
- package/dist/Volcano-HRG5EFWH.js +2443 -0
- package/dist/Volcano-HRG5EFWH.js.map +7 -0
- package/dist/Wsi-OHRCGYYD.js +629 -0
- package/dist/adSandbox-H56B25WR.js +33 -0
- package/dist/animatedBubbleChart-7SXFHU4J.js +547 -0
- package/dist/app-22JCSULA.js +42 -0
- package/dist/app-RGZJB6LN.js +32 -0
- package/dist/app.js +14 -14
- package/dist/bam-HA65TRGX.js +876 -0
- package/dist/barchart-6XO75OMA.js +42 -0
- package/dist/barchart2-6E5BIRHD.js +309 -0
- package/dist/block-43KNTXZ5.js +6250 -0
- package/dist/block-43KNTXZ5.js.map +7 -0
- package/dist/block.init-TPU5QIPA.js +33 -0
- package/dist/block.mds.expressionrank-QZDRFXCH.js +354 -0
- package/dist/block.mds.geneboxplot-64QVBK5Q.js +823 -0
- package/dist/block.mds.junction-I4J6VXNT.js +1539 -0
- package/dist/block.mds.svcnv-GDQMSQFF.js +6796 -0
- package/dist/block.svg-2MZFT5QP.js +159 -0
- package/dist/block.tk.aicheck-2MKHF6LX.js +278 -0
- package/dist/block.tk.ase-CLYGKFTS.js +360 -0
- package/dist/block.tk.bam-XTR4QA5Z.js +1901 -0
- package/dist/block.tk.bedgraphdot-A2P2CXRU.js +379 -0
- package/dist/block.tk.bigwig.ui-YZH6JXEO.js +206 -0
- package/dist/block.tk.hicstraw-QBK5VWGU.js +818 -0
- package/dist/block.tk.junction-5DEVBA7G.js +2358 -0
- package/dist/block.tk.junction.textmatrixui-7TTQMO6W.js +194 -0
- package/dist/block.tk.ld-PRIVUPKL.js +94 -0
- package/dist/block.tk.menu-JGBRFSS3.js +1024 -0
- package/dist/block.tk.pgv-KQJCJMVD.js +938 -0
- package/dist/brainImaging-4SLVJ2HV.js +555 -0
- package/dist/brainRegions-BDIVM2SG.js +217 -0
- package/dist/bubbleHeatmap-ORKFJNEQ.js +378 -0
- package/dist/cellTypeBubbleHeatmap-VOHLI4P7.js +278 -0
- package/dist/chunk-26N3B2JO.js +194 -0
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- package/dist/chunk-EDZJ3VNZ.js +54 -0
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- package/dist/chunk-FSLOUTTK.js.map +7 -0
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- package/dist/chunk-IAB2PRIH.js.map +7 -0
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- package/dist/chunk-IJ7AIDEO.js +302 -0
- package/dist/chunk-JBFVJHZN.js +1233 -0
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- package/dist/chunk-KIAMLQ7S.js.map +7 -0
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- package/dist/chunk-VA57CUC7.js.map +7 -0
- package/dist/chunk-VH5W6ODW.js +294 -0
- package/dist/chunk-VROF55EH.js +255 -0
- package/dist/chunk-VROF55EH.js.map +7 -0
- package/dist/chunk-VWA7BYSV.js +217 -0
- package/dist/chunk-X37BRSGS.js +102 -0
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- package/dist/chunk-XXPUZVS4.js +237 -0
- package/dist/chunk-XXPUZVS4.js.map +7 -0
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- package/dist/chunk-ZZN7ZD7J.js +54 -0
- package/dist/cohort-6OCRQQ2S.js +70 -0
- package/dist/condition-SZVXH3VU.js +327 -0
- package/dist/controls-MO6ZND76.js +34 -0
- package/dist/controls.config-P4MSTGL4.js +34 -0
- package/dist/correlation-NMI3CM3T.js +95 -0
- package/dist/customdata.inputui-VCHSCA65.js +284 -0
- package/dist/dataDownload-VQHOTQ5D.js +329 -0
- package/dist/databrowser.ui-ZFOCAG32.js +425 -0
- package/dist/dictionary-S5YCFUWH.js +113 -0
- package/dist/dnaMethylation-MQZLZRGT.js +33 -0
- package/dist/dnaMethylation.integration.spec-H546EBUO.js +198 -0
- package/dist/dofetch-QZIYSC7H.js +48 -0
- package/dist/e2pca-XOXOS3PN.js +344 -0
- package/dist/ep-U6KRL7FR.js +1249 -0
- package/dist/expclust.gdc.spec-HCK65C63.js +302 -0
- package/dist/facet-DCC25KJO.js +519 -0
- package/dist/gb-TIFWFD4Y.js +81 -0
- package/dist/geneExpClustering-6DQEOTOY.js +244 -0
- package/dist/geneExpression-EASRAN6B.js +310 -0
- package/dist/geneExpression-G4YMDCBH.js +33 -0
- package/dist/geneExpression.unit.spec-XVEJYMPX.js +128 -0
- package/dist/geneExpression.unit.spec-XVEJYMPX.js.map +7 -0
- package/dist/geneORA-6UBS5GSC.js +273 -0
- package/dist/geneRanking-UXXYWHNB.js +548 -0
- package/dist/geneVariant-SZRJOXVC.js +289 -0
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- package/dist/genefusion.ui-TJLYXSVL.js +303 -0
- package/dist/geneset-YTBDLEIH.js +203 -0
- package/dist/genomeBrowser.spec-ZO4LFIXE.js +276 -0
- package/dist/grin2-FC4VYU54.js +949 -0
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- package/dist/hierCluster-56EGAPOR.js +59 -0
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- package/dist/profileForms-GD7BIOOD.js +941 -0
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- /package/dist/{sampleView-BDC2WPH7.js.map → sampleView-WB74RLD7.js.map} +0 -0
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- /package/dist/{summarizeMutationSurvival-ABJ5RL4L.js.map → summarizeMutationSurvival-J7H7L4FX.js.map} +0 -0
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// plots/geneRanking.ts
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var Integrative_rank_COLUMN = "Integrative rank";
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var MISSING_COLOR = "#d9d9d9";
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var GeneRanking = class _GeneRanking extends PlotBase {
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constructor(opts, api) {
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/** identity-tag of the data the current heatmap was rendered for; used to abort stale responses */
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this.type = _GeneRanking.type;
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const main = opts.holder.append("div").style("padding", "12px").style("max-width", "95vw");
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this.toolbarDiv = main.append("div").style("display", "none").style("align-items", "center").style("justify-content", "space-between").style("flex-wrap", "wrap").style("gap", "8px").style("margin-bottom", "6px").style("font-size", "12px");
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const leftBar = this.toolbarDiv.append("div").style("display", "flex").style("align-items", "center").style("gap", "6px");
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const dlBtn = leftBar.append("button").style("display", "inline-flex").style("align-items", "center").style("gap", "6px").style("padding", "4px 10px").style("cursor", "pointer").on("click", () => this.downloadAll());
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icons["download"](dlBtn.append("span").style("display", "inline-flex").style("align-items", "center"), {
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this.searchInput = rightBar.append("input").attr("type", "search").attr("placeholder", "gene name").style("padding", "3px 6px").on("input", (event) => {
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this.noteDiv = main.append("div").style("display", "none").style("font-size", "0.85em").style("color", "#555").style("margin-bottom", "10px").style("line-height", "1.4").style("white-space", "normal").style("word-break", "normal").style("overflow-wrap", "break-word");
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const hmHeader = this.heatmapSection.append("div").style("display", "flex").style("align-items", "center").style("gap", "12px").style("margin-bottom", "8px");
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hmHeader.append("div").style("font-weight", "bold").text("Heatmap of the current page");
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orderSelect.append("option").attr("value", "clustered").text("Clustered").property("selected", true);
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const minAssaysWrap = this.heatmapControls.append("span").attr("class", "sjpp-mr-min-assays-wrap").style("display", "inline-flex").style("align-items", "center").style("gap", "6px");
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minAssaysWrap.append("span").style("font-size", "0.85em").style("color", "#555").text("Min assays:");
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});
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this.heatmapStatus = this.heatmapSection.append("div").style("font-size", "0.85em").style("color", "#777").style("margin-bottom", "6px");
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this.dom = {
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header: opts.header,
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loadingDiv: this.loadingDiv,
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toolbarDiv: this.toolbarDiv,
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};
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}
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static {
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this.type = "geneRanking";
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}
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getState(appState) {
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const config = appState.plots.find((p) => p.id === this.id);
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if (!config) throw `No plot with id='${this.id}' found`;
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return { config, vocab: appState.vocab, termdbConfig: appState.termdbConfig };
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}
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reactsTo(action) {
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}
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async main() {
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this.config = structuredClone(this.state.config);
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const key = this.config.rankingKey;
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}
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if (this.dom.header)
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this.dom.header.html(`${key} <span style="font-size:.8em;opacity:.7">MULTIOMIC RANKINGS</span>`);
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this.tableDiv.selectAll("*").remove();
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try {
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const resp = await dofetch3("termdb/geneRanking", {
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body: {
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genome: this.state.vocab.genome,
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key
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});
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const integrativeRankIdx = resp.columns.indexOf(Integrative_rank_COLUMN);
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} catch (e) {
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sayerror(this.errDiv.style("display", "block"), e.message || e);
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}
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this.loadingDiv.style("display", "none");
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}
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this.toolbarDiv.style("display", "flex");
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const desc = this.state.termdbConfig?.queries?.geneRanking?.description;
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this.noteDiv.style("display", desc ? "block" : "none").text(desc || "");
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this.renderTable();
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}
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downloadAll() {
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const gene = r[0];
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return typeof gene === "string" && gene.toLowerCase().includes(this.searchQuery);
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}) : rows;
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const sorted = this.sortIdx >= 0 ? sortRows(filtered, this.sortIdx, this.sortAsc) : filtered;
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}
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const blob = new Blob([lines.join("\n")], { type: "text/tab-separated-values" });
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const url = URL.createObjectURL(blob);
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const a = document.createElement("a");
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const slug = (this.dataKey || "geneRanking").replace(/[^A-Za-z0-9_-]+/g, "_");
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a.href = url;
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a.download = `${slug}.tsv`;
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document.body.appendChild(a);
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a.click();
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document.body.removeChild(a);
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URL.revokeObjectURL(url);
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}
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renderTable() {
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if (!this.cachedData) return;
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const { columns, rows } = this.cachedData;
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const filtered = this.searchQuery ? rows.filter((r) => {
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const gene = r[0];
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return typeof gene === "string" && gene.toLowerCase().includes(this.searchQuery);
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194
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}) : rows;
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const sortedRows = this.sortIdx >= 0 ? sortRows(filtered, this.sortIdx, this.sortAsc) : filtered;
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const cols = columns.map((label, i) => ({
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label,
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sortable: true,
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align: i === 0 ? "left" : "right",
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nowrap: i === 0
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}));
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const tableRows = sortedRows.map(
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(row) => row.map((v) => {
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if (v === null || v === void 0) return { value: "" };
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205
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if (typeof v === "number") return { value: roundValueAuto(v) };
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return { value: v };
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})
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);
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this.tableDiv.selectAll("*").remove();
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|
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renderTable({
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|
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columns: cols,
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rows: tableRows,
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div: this.tableDiv,
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showLines: true,
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striped: true,
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|
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showHeader: true,
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|
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header: { allowSort: false },
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|
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maxWidth: "95vw",
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|
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maxHeight: "70vh",
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pagination: {
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pageSize: this.pageSize,
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|
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pageSizeOptions: [10, 25, 50, 100],
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|
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currentPage: this.currentPage,
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224
|
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onChange: ({ currentPage, pageSize }) => {
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|
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this.currentPage = currentPage;
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|
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this.pageSize = pageSize;
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227
|
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this.renderHeatmap();
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|
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}
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|
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}
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|
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});
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|
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const ths = this.tableDiv.selectAll("thead th");
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232
|
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ths.each((_d, i, nodes) => {
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const th = nodes[i];
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234
|
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th.style.cursor = "pointer";
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|
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th.style.userSelect = "none";
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236
|
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th.style.whiteSpace = "nowrap";
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237
|
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th.style.color = "#000";
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238
|
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th.style.fontWeight = "bold";
|
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239
|
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th.style.opacity = "1";
|
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240
|
-
const colIdx = i;
|
|
241
|
-
const label = columns[colIdx];
|
|
242
|
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if (!label) return;
|
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243
|
-
const active = this.sortIdx === colIdx;
|
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244
|
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const upColor = active && this.sortAsc ? "#000" : "#ccc";
|
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245
|
-
const downColor = active && !this.sortAsc ? "#000" : "#ccc";
|
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246
|
-
th.innerHTML = `<span>${escapeHtml(label)}</span><span style="display:inline-flex;flex-direction:column;line-height:0.6em;margin-left:4px;vertical-align:middle;font-size:0.7em;"><span style="color:${upColor}">\u25B2</span><span style="color:${downColor}">\u25BC</span></span>`;
|
|
247
|
-
th.onclick = () => {
|
|
248
|
-
if (this.sortIdx === colIdx) this.sortAsc = !this.sortAsc;
|
|
249
|
-
else {
|
|
250
|
-
this.sortIdx = colIdx;
|
|
251
|
-
this.sortAsc = true;
|
|
252
|
-
}
|
|
253
|
-
this.currentPage = 1;
|
|
254
|
-
this.renderTable();
|
|
255
|
-
};
|
|
256
|
-
});
|
|
257
|
-
requestAnimationFrame(() => {
|
|
258
|
-
const wrapper = this.tableDiv.select(":scope > div").node();
|
|
259
|
-
const measured = wrapper || this.tableDiv.select("table").node();
|
|
260
|
-
if (!measured) return;
|
|
261
|
-
const w = measured.getBoundingClientRect().width;
|
|
262
|
-
if (w > 0) {
|
|
263
|
-
const px = `${Math.ceil(w)}px`;
|
|
264
|
-
this.toolbarDiv.style("width", px).style("box-sizing", "border-box");
|
|
265
|
-
this.noteDiv.style("width", px).style("box-sizing", "border-box");
|
|
266
|
-
}
|
|
267
|
-
});
|
|
268
|
-
this.renderHeatmap();
|
|
269
|
-
}
|
|
270
|
-
/** rows displayed on the current page after filter + sort + pagination */
|
|
271
|
-
getVisibleRows() {
|
|
272
|
-
if (!this.cachedData) return [];
|
|
273
|
-
const { rows } = this.cachedData;
|
|
274
|
-
const filtered = this.searchQuery ? rows.filter((r) => {
|
|
275
|
-
const gene = r[0];
|
|
276
|
-
return typeof gene === "string" && gene.toLowerCase().includes(this.searchQuery);
|
|
277
|
-
}) : rows;
|
|
278
|
-
const sorted = this.sortIdx >= 0 ? sortRows(filtered, this.sortIdx, this.sortAsc) : filtered;
|
|
279
|
-
const start = (this.currentPage - 1) * this.pageSize;
|
|
280
|
-
return sorted.slice(start, start + this.pageSize);
|
|
281
|
-
}
|
|
282
|
-
async renderHeatmap() {
|
|
283
|
-
if (!this.cachedData) {
|
|
284
|
-
this.heatmapSection.style("display", "none");
|
|
285
|
-
return;
|
|
286
|
-
}
|
|
287
|
-
const { columns } = this.cachedData;
|
|
288
|
-
const colNameToIdx = new Map(columns.map((c, i) => [c, i]));
|
|
289
|
-
const modalities = this.state.termdbConfig?.queries?.geneRanking?.modalities || [];
|
|
290
|
-
const usedCols = modalities.filter((m) => colNameToIdx.has(m));
|
|
291
|
-
if (usedCols.length < 2) {
|
|
292
|
-
this.heatmapSection.style("display", "none");
|
|
293
|
-
return;
|
|
294
|
-
}
|
|
295
|
-
this.heatmapSection.style("display", "block");
|
|
296
|
-
if (this.minAssays > usedCols.length) this.minAssays = usedCols.length;
|
|
297
|
-
if (this.minAssays < 2) this.minAssays = 2;
|
|
298
|
-
const optionVals = this.minAssaysSelect.selectAll("option").nodes().map((o) => Number(o.value));
|
|
299
|
-
const want = Array.from({ length: usedCols.length - 1 }, (_, i) => i + 2);
|
|
300
|
-
if (optionVals.length !== want.length || optionVals.some((v, i) => v !== want[i])) {
|
|
301
|
-
this.minAssaysSelect.selectAll("option").remove();
|
|
302
|
-
for (const n of want) {
|
|
303
|
-
this.minAssaysSelect.append("option").attr("value", n).text(String(n)).property("selected", n === this.minAssays);
|
|
304
|
-
}
|
|
305
|
-
}
|
|
306
|
-
const visible = this.getVisibleRows();
|
|
307
|
-
const geneNames = visible.map((r) => String(r[0]));
|
|
308
|
-
const matrix = visible.map(
|
|
309
|
-
(r) => usedCols.map((c) => {
|
|
310
|
-
const v = r[colNameToIdx.get(c)];
|
|
311
|
-
return typeof v === "number" && Number.isFinite(v) ? v : null;
|
|
312
|
-
})
|
|
313
|
-
);
|
|
314
|
-
const fullStats = computeColStats(
|
|
315
|
-
this.cachedData.rows,
|
|
316
|
-
usedCols.map((c) => colNameToIdx.get(c))
|
|
317
|
-
);
|
|
318
|
-
const toPct = (val, c) => {
|
|
319
|
-
if (val === null || !Number.isFinite(val)) return null;
|
|
320
|
-
const lo = fullStats.min[c];
|
|
321
|
-
const hi = fullStats.max[c];
|
|
322
|
-
if (!Number.isFinite(lo) || !Number.isFinite(hi) || hi === lo) return 0;
|
|
323
|
-
return (val - lo) / (hi - lo);
|
|
324
|
-
};
|
|
325
|
-
const buildPct = (raw) => raw.map((row) => row.map((v, c) => toPct(v, c)));
|
|
326
|
-
const renderKey = `${this.dataKey}|${this.heatmapOrder}|${this.minAssays}|${this.currentPage}|${this.pageSize}|${this.searchQuery}|${this.sortIdx}|${this.sortAsc}|${geneNames.join(",")}`;
|
|
327
|
-
this.heatmapRenderKey = renderKey;
|
|
328
|
-
this.heatmapDiv.selectAll("*").remove();
|
|
329
|
-
this.heatmapStatus.text("Computing heatmap\u2026");
|
|
330
|
-
this.heatmapControls.select(".sjpp-mr-min-assays-wrap").style("display", this.heatmapOrder === "clustered" ? "inline-flex" : "none");
|
|
331
|
-
if (this.heatmapOrder === "rank") {
|
|
332
|
-
if (geneNames.length < 1) {
|
|
333
|
-
this.heatmapStatus.text("No rows to display.");
|
|
334
|
-
return;
|
|
335
|
-
}
|
|
336
|
-
this.heatmapStatus.text(
|
|
337
|
-
`${geneNames.length} rows in current page order. Missing values shown in gray; cells colored by rank within the full dataset per column (lower = better).`
|
|
338
|
-
);
|
|
339
|
-
this.drawHeatmap({
|
|
340
|
-
rowNames: geneNames,
|
|
341
|
-
colNames: usedCols,
|
|
342
|
-
matrix: buildPct(matrix),
|
|
343
|
-
rankMatrix: matrix,
|
|
344
|
-
totals: fullStats.n,
|
|
345
|
-
dendrogram: null
|
|
346
|
-
});
|
|
347
|
-
return;
|
|
348
|
-
}
|
|
349
|
-
try {
|
|
350
|
-
const resp = await dofetch3("termdb/geneRanking", {
|
|
351
|
-
body: {
|
|
352
|
-
for: "cluster",
|
|
353
|
-
matrix,
|
|
354
|
-
row_names: geneNames,
|
|
355
|
-
col_names: usedCols,
|
|
356
|
-
minAssays: this.minAssays
|
|
357
|
-
}
|
|
358
|
-
});
|
|
359
|
-
if (renderKey !== this.heatmapRenderKey) return;
|
|
360
|
-
if (resp.error) throw resp.error;
|
|
361
|
-
const keptCount = resp.usedRowNames?.length ?? 0;
|
|
362
|
-
this.heatmapStatus.text(
|
|
363
|
-
`${keptCount} of ${visible.length} rows shown (proteins with \u2265${this.minAssays} assays). Missing values shown in gray; cells colored by rank within the full dataset per column (lower = better).`
|
|
364
|
-
);
|
|
365
|
-
const nameToIdx = new Map(geneNames.map((n, i) => [n, i]));
|
|
366
|
-
const keptRawMatrix = resp.usedRowNames.map((n) => matrix[nameToIdx.get(n)]);
|
|
367
|
-
const keptNameToIdx = new Map(resp.usedRowNames.map((n, i) => [n, i]));
|
|
368
|
-
const orderedRowNames = resp.row.order.map((o) => o.name);
|
|
369
|
-
const orderedRank = orderedRowNames.map((name) => keptRawMatrix[keptNameToIdx.get(name)]);
|
|
370
|
-
const orderedPct = buildPct(orderedRank);
|
|
371
|
-
this.drawHeatmap({
|
|
372
|
-
rowNames: orderedRowNames,
|
|
373
|
-
colNames: resp.usedColNames,
|
|
374
|
-
matrix: orderedPct,
|
|
375
|
-
rankMatrix: orderedRank,
|
|
376
|
-
totals: fullStats.n,
|
|
377
|
-
dendrogram: resp.row
|
|
378
|
-
});
|
|
379
|
-
} catch (e) {
|
|
380
|
-
if (renderKey !== this.heatmapRenderKey) return;
|
|
381
|
-
this.heatmapStatus.text(`Heatmap error: ${e?.message || e}`);
|
|
382
|
-
}
|
|
383
|
-
}
|
|
384
|
-
drawHeatmap(opts) {
|
|
385
|
-
const { rowNames, colNames, matrix, rankMatrix, totals, dendrogram } = opts;
|
|
386
|
-
const cellW = 44;
|
|
387
|
-
const cellH = 22;
|
|
388
|
-
const dendroW = dendrogram ? 110 : 0;
|
|
389
|
-
const dendroPad = dendrogram ? 8 : 0;
|
|
390
|
-
const colLabelH = 110;
|
|
391
|
-
const rowLabelW = 130;
|
|
392
|
-
const legendBlockW = 110;
|
|
393
|
-
const gridW = colNames.length * cellW;
|
|
394
|
-
const gridH = rowNames.length * cellH;
|
|
395
|
-
const legendGradH = Math.max(120, Math.min(gridH, 240));
|
|
396
|
-
const missingSwatchExtra = 18 + 12;
|
|
397
|
-
const totalW = dendroW + dendroPad + gridW + 8 + rowLabelW + legendBlockW;
|
|
398
|
-
const totalH = colLabelH + Math.max(gridH, legendGradH + missingSwatchExtra) + 16;
|
|
399
|
-
this.heatmapDiv.selectAll("*").remove();
|
|
400
|
-
const svg = this.heatmapDiv.append("svg").attr("width", totalW).attr("height", totalH).attr("font-family", "sans-serif");
|
|
401
|
-
const seq = linear().domain([0, 1]).range([SEQ_COLOR_LOW, SEQ_COLOR_HIGH]).clamp(true);
|
|
402
|
-
const color = (v) => seq(v);
|
|
403
|
-
if (dendrogram) {
|
|
404
|
-
const g = svg.append("g").attr("transform", `translate(0,${colLabelH})`);
|
|
405
|
-
drawRowDendrogram(g, dendrogram, dendroW, gridH, cellH);
|
|
406
|
-
}
|
|
407
|
-
const gridX = dendroW + dendroPad;
|
|
408
|
-
const labelsG = svg.append("g").attr("transform", `translate(${gridX},${colLabelH - 4})`);
|
|
409
|
-
labelsG.selectAll("text").data(colNames).enter().append("text").attr("x", (_d, i) => i * cellW + cellW / 2).attr("y", 0).attr("transform", (_d, i) => `rotate(-45,${i * cellW + cellW / 2},0)`).attr("text-anchor", "start").attr("font-size", "13px").attr("fill", "#000").text((d) => d);
|
|
410
|
-
const cellsG = svg.append("g").attr("transform", `translate(${gridX},${colLabelH})`);
|
|
411
|
-
const cellData = [];
|
|
412
|
-
for (let r = 0; r < matrix.length; r++) {
|
|
413
|
-
for (let c = 0; c < matrix[r].length; c++) {
|
|
414
|
-
cellData.push({ x: c * cellW, y: r * cellH, v: matrix[r][c], row: r, col: c });
|
|
415
|
-
}
|
|
416
|
-
}
|
|
417
|
-
cellsG.selectAll("rect").data(cellData).enter().append("rect").attr("x", (d) => d.x).attr("y", (d) => d.y).attr("width", cellW).attr("height", cellH).attr("fill", (d) => d.v === null || !Number.isFinite(d.v) ? MISSING_COLOR : color(d.v)).attr("stroke", "#fff").attr("stroke-width", 0.5).append("title").text((d) => {
|
|
418
|
-
if (d.v === null || !Number.isFinite(d.v)) return `${rowNames[d.row]} \u2014 ${colNames[d.col]}
|
|
419
|
-
missing`;
|
|
420
|
-
const r = rankMatrix[d.row][d.col];
|
|
421
|
-
const n = totals[d.col];
|
|
422
|
-
const rStr = Number.isInteger(r) ? String(r) : r.toFixed(1);
|
|
423
|
-
return `${rowNames[d.row]} \u2014 ${colNames[d.col]}
|
|
424
|
-
rank: ${rStr} of ${n}
|
|
425
|
-
scaled rank: ${d.v.toFixed(
|
|
426
|
-
3
|
|
427
|
-
)}`;
|
|
428
|
-
});
|
|
429
|
-
cellsG.selectAll("text.sjpp-mr-rank").data(cellData.filter((d) => d.v !== null && Number.isFinite(d.v))).enter().append("text").attr("class", "sjpp-mr-rank").attr("x", (d) => d.x + cellW / 2).attr("y", (d) => d.y + cellH / 2 + 3).attr("text-anchor", "middle").attr("font-size", "9px").attr("font-weight", 300).attr("pointer-events", "none").attr("fill", (d) => d.v < 0.5 ? "rgba(255,255,255,0.85)" : "rgba(40,40,40,0.7)").text((d) => {
|
|
430
|
-
const r = rankMatrix[d.row][d.col];
|
|
431
|
-
return Number.isInteger(r) ? String(r) : r.toFixed(1);
|
|
432
|
-
});
|
|
433
|
-
const rowLabelsG = svg.append("g").attr("transform", `translate(${gridX + gridW + 6},${colLabelH})`);
|
|
434
|
-
rowLabelsG.selectAll("text").data(rowNames).enter().append("text").attr("x", 0).attr("y", (_d, i) => i * cellH + cellH / 2 + 4).attr("font-size", "13px").attr("fill", "#000").text((d) => d);
|
|
435
|
-
const legendGradW = 16;
|
|
436
|
-
const legendX = gridX + gridW + 8 + rowLabelW + 8;
|
|
437
|
-
const legendY = colLabelH;
|
|
438
|
-
const legendG = svg.append("g").attr("transform", `translate(${legendX},${legendY})`);
|
|
439
|
-
legendG.append("text").attr("transform", `translate(-6,${legendGradH / 2}) rotate(-90)`).attr("text-anchor", "middle").attr("font-size", "11px").attr("fill", "#555").text("scaled rank (per column)");
|
|
440
|
-
const stops = 32;
|
|
441
|
-
for (let i = 0; i < stops; i++) {
|
|
442
|
-
const v = i / (stops - 1);
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443
|
-
legendG.append("rect").attr("x", 0).attr("y", i * legendGradH / stops).attr("width", legendGradW).attr("height", legendGradH / stops + 0.5).attr("fill", color(v));
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444
|
-
}
|
|
445
|
-
legendG.append("rect").attr("x", 0).attr("y", 0).attr("width", legendGradW).attr("height", legendGradH).attr("fill", "none").attr("stroke", "#999").attr("stroke-width", 0.5);
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446
|
-
const maxRank = totals.reduce((m, t) => Number.isFinite(t) && t > m ? t : m, 0);
|
|
447
|
-
const midRank = Math.round((1 + maxRank) / 2);
|
|
448
|
-
legendG.append("text").attr("x", legendGradW + 6).attr("y", 4).attr("font-size", "11px").text("1 (top)");
|
|
449
|
-
legendG.append("text").attr("x", legendGradW + 6).attr("y", legendGradH / 2 + 4).attr("font-size", "11px").text(String(midRank));
|
|
450
|
-
legendG.append("text").attr("x", legendGradW + 6).attr("y", legendGradH).attr("font-size", "11px").text(`${maxRank} (bottom)`);
|
|
451
|
-
const missingG = svg.append("g").attr("transform", `translate(${legendX},${legendY + legendGradH + 18})`);
|
|
452
|
-
missingG.append("rect").attr("width", legendGradW).attr("height", 12).attr("fill", MISSING_COLOR).attr("stroke", "#999").attr("stroke-width", 0.5);
|
|
453
|
-
missingG.append("text").attr("x", legendGradW + 6).attr("y", 10).attr("font-size", "11px").attr("fill", "#555").text("missing");
|
|
454
|
-
}
|
|
455
|
-
};
|
|
456
|
-
function escapeHtml(s) {
|
|
457
|
-
return s.replace(/[&<>"']/g, (c) => ({ "&": "&", "<": "<", ">": ">", '"': """, "'": "'" })[c]);
|
|
458
|
-
}
|
|
459
|
-
function sortRows(rows, idx, asc) {
|
|
460
|
-
const sign = asc ? 1 : -1;
|
|
461
|
-
return rows.map((r, i) => ({ r, i })).sort((a, b) => {
|
|
462
|
-
const va = a.r[idx];
|
|
463
|
-
const vb = b.r[idx];
|
|
464
|
-
if (va == null && vb == null) return a.i - b.i;
|
|
465
|
-
if (va == null) return 1;
|
|
466
|
-
if (vb == null) return -1;
|
|
467
|
-
if (typeof va === "number" && typeof vb === "number") return (va - vb) * sign;
|
|
468
|
-
return String(va).localeCompare(String(vb)) * sign;
|
|
469
|
-
}).map((x) => x.r);
|
|
470
|
-
}
|
|
471
|
-
function computeColStats(allRows, colIdxs) {
|
|
472
|
-
const min = colIdxs.map(() => Infinity);
|
|
473
|
-
const max = colIdxs.map(() => -Infinity);
|
|
474
|
-
const n = colIdxs.map(() => 0);
|
|
475
|
-
for (const row of allRows) {
|
|
476
|
-
for (let i = 0; i < colIdxs.length; i++) {
|
|
477
|
-
const v = row[colIdxs[i]];
|
|
478
|
-
if (typeof v === "number" && Number.isFinite(v)) {
|
|
479
|
-
if (v < min[i]) min[i] = v;
|
|
480
|
-
if (v > max[i]) max[i] = v;
|
|
481
|
-
n[i]++;
|
|
482
|
-
}
|
|
483
|
-
}
|
|
484
|
-
}
|
|
485
|
-
return { min, max, n };
|
|
486
|
-
}
|
|
487
|
-
function drawRowDendrogram(g, dend, width, gridH, cellH) {
|
|
488
|
-
const heights = dend.height.map((h) => h.height);
|
|
489
|
-
const maxH = Math.max(...heights, 1e-9);
|
|
490
|
-
const hToX = linear().domain([0, maxH]).range([width, 0]);
|
|
491
|
-
const leafYByName = /* @__PURE__ */ new Map();
|
|
492
|
-
dend.order.forEach((leaf, i) => {
|
|
493
|
-
leafYByName.set(leaf.name, i * cellH + cellH / 2);
|
|
494
|
-
});
|
|
495
|
-
const merged = /* @__PURE__ */ new Map();
|
|
496
|
-
for (let i = 0; i < dend.merge.length; i++) {
|
|
497
|
-
const { n1, n2 } = dend.merge[i];
|
|
498
|
-
const pos = (n) => {
|
|
499
|
-
if (n < 0) {
|
|
500
|
-
const name = dend.inputOrder[-n - 1];
|
|
501
|
-
return { x: width, y: leafYByName.get(name) ?? 0 };
|
|
502
|
-
}
|
|
503
|
-
return merged.get(n) || { x: width, y: 0 };
|
|
504
|
-
};
|
|
505
|
-
const a = pos(n1);
|
|
506
|
-
const b = pos(n2);
|
|
507
|
-
const x = hToX(heights[i]);
|
|
508
|
-
const y = (a.y + b.y) / 2;
|
|
509
|
-
g.append("line").attr("x1", a.x).attr("x2", x).attr("y1", a.y).attr("y2", a.y).attr("stroke", "#000").attr("stroke-width", 1);
|
|
510
|
-
g.append("line").attr("x1", b.x).attr("x2", x).attr("y1", b.y).attr("y2", b.y).attr("stroke", "#000").attr("stroke-width", 1);
|
|
511
|
-
g.append("line").attr("x1", x).attr("x2", x).attr("y1", a.y).attr("y2", b.y).attr("stroke", "#000").attr("stroke-width", 1);
|
|
512
|
-
merged.set(i + 1, { x, y });
|
|
513
|
-
}
|
|
514
|
-
}
|
|
515
|
-
async function getPlotConfig(opts) {
|
|
516
|
-
const config = {
|
|
517
|
-
chartType: GeneRanking.type,
|
|
518
|
-
rankingKey: opts.rankingKey || ""
|
|
519
|
-
};
|
|
520
|
-
return copyMerge(config, opts);
|
|
521
|
-
}
|
|
522
|
-
var componentInit = getCompInit(GeneRanking);
|
|
523
|
-
function makeChartBtnMenu(holder, chartsInstance) {
|
|
524
|
-
chartsInstance.dom.tip.clear();
|
|
525
|
-
const cfg = chartsInstance.state.termdbConfig?.queries?.geneRanking;
|
|
526
|
-
const rankings = cfg?.rankings;
|
|
527
|
-
if (!rankings || !Object.keys(rankings).length) {
|
|
528
|
-
holder.append("div").style("padding", "8px").style("color", "#888").text("No multiomic rankings available for this dataset.");
|
|
529
|
-
return;
|
|
530
|
-
}
|
|
531
|
-
for (const key of Object.keys(rankings)) {
|
|
532
|
-
holder.append("div").attr("class", "sja_menuoption sja_sharp_border").text(key).on("click", () => {
|
|
533
|
-
chartsInstance.dom.tip.hide();
|
|
534
|
-
chartsInstance.prepPlot({
|
|
535
|
-
config: {
|
|
536
|
-
chartType: "geneRanking",
|
|
537
|
-
rankingKey: key
|
|
538
|
-
}
|
|
539
|
-
});
|
|
540
|
-
});
|
|
541
|
-
}
|
|
542
|
-
}
|
|
543
|
-
export {
|
|
544
|
-
componentInit,
|
|
545
|
-
getPlotConfig,
|
|
546
|
-
makeChartBtnMenu
|
|
547
|
-
};
|
|
548
|
-
//# sourceMappingURL=geneRanking-JRAU6FMJ.js.map
|
|
@@ -1,36 +0,0 @@
|
|
|
1
|
-
import {
|
|
2
|
-
SearchHandler,
|
|
3
|
-
addParentTerm,
|
|
4
|
-
getChildTerms
|
|
5
|
-
} from "./chunk-QJ3HYZH3.js";
|
|
6
|
-
import "./chunk-HJ6L54YS.js";
|
|
7
|
-
import "./chunk-KV4W2ACA.js";
|
|
8
|
-
import "./chunk-DMWOK4DS.js";
|
|
9
|
-
import "./chunk-ELJX3QIQ.js";
|
|
10
|
-
import "./chunk-5IMFPVGT.js";
|
|
11
|
-
import "./chunk-EEB5VE2A.js";
|
|
12
|
-
import "./chunk-6RRZRISL.js";
|
|
13
|
-
import "./chunk-2KM4PRQM.js";
|
|
14
|
-
import "./chunk-VMRO6DMC.js";
|
|
15
|
-
import "./chunk-HKKTNIMX.js";
|
|
16
|
-
import "./chunk-GMRIEUBW.js";
|
|
17
|
-
import "./chunk-4EZLVENZ.js";
|
|
18
|
-
import "./chunk-WINIL2KN.js";
|
|
19
|
-
import "./chunk-PF4DSFDR.js";
|
|
20
|
-
import "./chunk-7X6NF7NI.js";
|
|
21
|
-
import "./chunk-W5J3LTYS.js";
|
|
22
|
-
import "./chunk-Z2ZITHT4.js";
|
|
23
|
-
import "./chunk-4OLM3KSB.js";
|
|
24
|
-
import "./chunk-FXQXCOII.js";
|
|
25
|
-
import "./chunk-TLT4YIG3.js";
|
|
26
|
-
import "./chunk-5R63Q5KH.js";
|
|
27
|
-
import "./chunk-I6Y4O3RR.js";
|
|
28
|
-
import "./chunk-Q5RDQNIT.js";
|
|
29
|
-
import "./chunk-DQC5FFGV.js";
|
|
30
|
-
import "./chunk-HS5PO5ZQ.js";
|
|
31
|
-
export {
|
|
32
|
-
SearchHandler,
|
|
33
|
-
addParentTerm,
|
|
34
|
-
getChildTerms
|
|
35
|
-
};
|
|
36
|
-
//# sourceMappingURL=geneVariant-3DZTWQFG.js.map
|