@sjcrh/proteinpaint-client 2.208.0 → 2.210.0

package/dist/CorrelationVolcano-33I4FC44.js

@@ -1,617 +0,0 @@
-import {
-  LegendCircleReference,
-  PlotBase,
-  appInit,
-  axisstyle,
-  controlsInit,
-  fillTermWrapper,
-  fillTwLst,
-  formatHeaderText,
-  table2col,
-  to_svg
-} from "./chunk-QJ3HYZH3.js";
-import "./chunk-HJ6L54YS.js";
-import "./chunk-KV4W2ACA.js";
-import "./chunk-DMWOK4DS.js";
-import {
-  Menu
-} from "./chunk-ELJX3QIQ.js";
-import "./chunk-5IMFPVGT.js";
-import "./chunk-EEB5VE2A.js";
-import "./chunk-6RRZRISL.js";
-import "./chunk-2KM4PRQM.js";
-import "./chunk-VMRO6DMC.js";
-import "./chunk-HKKTNIMX.js";
-import {
-  termType2label
-} from "./chunk-GMRIEUBW.js";
-import "./chunk-4EZLVENZ.js";
-import {
-  copyMerge,
-  getCompInit
-} from "./chunk-WINIL2KN.js";
-import "./chunk-PF4DSFDR.js";
-import "./chunk-7X6NF7NI.js";
-import "./chunk-W5J3LTYS.js";
-import {
-  axisBottom,
-  axisLeft
-} from "./chunk-Z2ZITHT4.js";
-import {
-  linear
-} from "./chunk-4OLM3KSB.js";
-import "./chunk-FXQXCOII.js";
-import {
-  roundValue
-} from "./chunk-TLT4YIG3.js";
-import "./chunk-5R63Q5KH.js";
-import {
-  select_default
-} from "./chunk-I6Y4O3RR.js";
-import "./chunk-Q5RDQNIT.js";
-import "./chunk-DQC5FFGV.js";
-import "./chunk-HS5PO5ZQ.js";
-
-// plots/corrVolcano/model/Model.ts
-var Model = class {
-  constructor(config, state, app, settings, variableTwLst, vocabApi) {
-    this.config = config;
-    this.state = state;
-    this.app = app;
-    this.settings = settings;
-    this.variableTwLst = variableTwLst;
-    this.vocabApi = vocabApi;
-  }
-  async getData() {
-    const opts = await this.setRequestOpts();
-    const data = await this.vocabApi.getCorrelationVolcanoData(opts);
-    return data;
-  }
-  async setRequestOpts() {
-    return {
-      featureTw: this.config.featureTw,
-      variableTwLst: this.variableTwLst,
-      filter: this.state.termfilter.filter,
-      filter0: this.state.termfilter.filter0,
-      correlationMethod: this.settings.method
-    };
-  }
-};
-
-// plots/corrVolcano/viewModel/ViewModel.ts
-var ViewModel = class {
-  constructor(config, data, dom, settings, variableTwLst) {
-    this.bottomPad = 60;
-    /** Only one side, left or right */
-    this.horizPad = 70;
-    this.topPad = 40;
-    this.variableTwLst = variableTwLst;
-    const pValueKey = settings.isAdjustedPValue ? "adjusted_pvalue" : "original_pvalue";
-    const d = this.transformPValues(data, pValueKey);
-    const [absYMax, absYMin] = this.setMinMax(d, `transformed_${pValueKey}`);
-    const [absXMax, absXMin] = this.setMinMax(d, "correlation");
-    const [absSampleMax, absSampleMin] = this.setMinMax(d, "sampleSize");
-    const plotDim = this.setPlotDimensions(config, settings, absYMax, absYMin, absXMax, absXMin);
-    this.viewData = {
-      plotDim,
-      variableItems: this.setVariablesData(absSampleMax, absSampleMin, d, dom, pValueKey, plotDim, settings),
-      legendData: this.setLegendData(absSampleMin, absSampleMax, data.skippedVariables)
-    };
-  }
-  transformPValues(data, key) {
-    data.variableItems = data.variableItems.filter((v) => v[key] > 0);
-    for (const item of data.variableItems) {
-      if (item[key] > 0) item[`transformed_${key}`] = -Math.log10(item[key]);
-      else item[key] = null;
-    }
-    return data;
-  }
-  setMinMax(data, key) {
-    const sortedValues = data.variableItems.map((v) => v[key]).sort((a, b) => a - b);
-    const max = sortedValues[sortedValues.length - 1];
-    const min = sortedValues[0];
-    return [max, min];
-  }
-  setPlotDimensions(config, settings, absYMax, absYMin, absXMax, absXMin) {
-    const maxXRange = Math.max(Math.abs(absXMin), absXMax);
-    const xScale = linear().domain(this.setDomain(-maxXRange, maxXRange, 0.05)).range([0, settings.width]);
-    const yScale = linear().domain(this.setDomain(absYMin, absYMax)).range([settings.height, 0]);
-    return {
-      svg: {
-        height: settings.height + this.topPad + this.bottomPad * 2,
-        width: settings.width + this.horizPad * 2
-      },
-      title: {
-        text: `${config.featureTw.term.name} ${termType2label(config.featureTw.term.type)}`,
-        x: this.horizPad + settings.width / 2,
-        y: this.topPad / 2
-      },
-      xAxisLabel: {
-        x: this.horizPad + settings.width / 2,
-        y: this.topPad + settings.height + this.bottomPad
-      },
-      yAxisLabel: {
-        x: this.horizPad / 3,
-        y: this.topPad + settings.height / 2
-      },
-      xScale: {
-        scale: xScale,
-        x: this.horizPad,
-        y: settings.height + this.topPad
-      },
-      yScale: {
-        //Do not use scaleLog() here. scaleLog is for raw values before the log transformation
-        //Using it will distort the values.
-        scale: yScale,
-        x: this.horizPad,
-        y: this.topPad
-      },
-      divideLine: {
-        x: xScale(0) + this.horizPad,
-        y1: settings.height + this.topPad,
-        y2: this.topPad
-      },
-      thresholdLine: {
-        y: yScale(-Math.log10(settings.threshold)) + this.topPad,
-        x1: this.horizPad,
-        x2: settings.width + this.horizPad
-      }
-    };
-  }
-  /** Increase the domain slightly so all data points fit within the plot */
-  setDomain(min, max, percent = 0.1) {
-    const rangeInc = (max - min) * percent;
-    const domain = [min - rangeInc, max + rangeInc];
-    return domain;
-  }
-  setVariablesData(absSampleMax, absSampleMin, data, dom, key, plotDim, settings) {
-    const radiusScale = linear().domain([absSampleMin, absSampleMax]).range([settings.radiusMin, settings.radiusMax]);
-    const renderedCircles = dom.plot?.selectAll("circle").nodes().map((d) => d.__data__);
-    for (const item of data.variableItems) {
-      item.color = item.correlation > 0 ? settings.corrColor : settings.antiCorrColor;
-      item.label = this.variableTwLst.find((t) => t.$id == item.tw$id).term.name;
-      item.x = plotDim.xScale.scale(item.correlation) + this.horizPad;
-      item.y = plotDim.yScale.scale(item[`transformed_${key}`]) + this.topPad;
-      item.radius = radiusScale(item.sampleSize);
-      if (renderedCircles?.length > 0) {
-        const findRenderdCircle = renderedCircles.find((d) => d.tw$id === item.tw$id);
-        if (findRenderdCircle) {
-          item.previousX = findRenderdCircle.x;
-          item.previousY = findRenderdCircle.y;
-        }
-      } else {
-        item.previousX = item.x;
-        item.previousY = item.y;
-      }
-    }
-    return data.variableItems;
-  }
-  setLegendData(absSampleMin, absSampleMax, skippedVariables) {
-    const opts = {
-      absMin: absSampleMin,
-      absMax: absSampleMax,
-      skippedVariables: skippedVariables.length == 0 ? [] : skippedVariables.map((t) => {
-        return { label: this.variableTwLst.find((tw) => tw.$id == t.tw$id).term.name };
-      })
-    };
-    return opts;
-  }
-};
-
-// plots/corrVolcano/view/ItemToolTip.ts
-var ItemToolTip = class {
-  constructor(item, circle, tip, settings) {
-    circle.on("mouseover", () => {
-      tip.clear().showunder(circle.node());
-      const table = table2col({ holder: tip.d.append("table") });
-      table.addRow("Item", item.label);
-      table.addRow("Correlation (\u03C1)", roundValue(item.correlation, 3));
-      const pValue = settings.isAdjustedPValue ? item.adjusted_pvalue : item.original_pvalue;
-      table.addRow(settings.isAdjustedPValue ? "Adjusted p value" : "Original p value", roundValue(pValue, 5));
-      table.addRow("Sample size", item.sampleSize);
-    });
-    circle.on("mouseout", () => {
-      tip.hide();
-    });
-  }
-};
-
-// plots/corrVolcano/view/View.ts
-var View = class {
-  constructor(dom, viewData, interactions, settings, defaultMaxRadius, defaultMinRadius) {
-    this.duration = 500;
-    this.dom = dom;
-    this.viewData = viewData;
-    interactions.clearDom();
-    const plotDim = viewData.plotDim;
-    this.renderDom(plotDim);
-    renderVariables(this, settings, interactions);
-    this.renderLegend(viewData.legendData, settings, interactions, defaultMaxRadius, defaultMinRadius);
-  }
-  renderDom(plotDim) {
-    this.dom.svg.attr("width", plotDim.svg.width).attr("height", plotDim.svg.height);
-    this.dom.title.attr("class", "sjpp-corr-volcano-title").style("font-weight", 600).attr("text-anchor", "middle").attr("x", plotDim.title.x).attr("y", plotDim.title.y).text(plotDim.title.text);
-    this.dom.yAxisLabel.attr("class", "sjpp-corr-volcano-y-axis").style("font-weight", 600).attr("text-anchor", "middle").attr("transform", `translate(${plotDim.yAxisLabel.x}, ${plotDim.yAxisLabel.y}) rotate(-90)`).text("-log10(p value)");
-    this.dom.xAxisLabel.attr("class", "sjpp-corr-volcano-x-axis").style("font-weight", 600).attr("text-anchor", "middle").attr("transform", `translate(${plotDim.xAxisLabel.x}, ${plotDim.xAxisLabel.y})`).html("Correlation Coefficient (ρ)");
-    this.renderScale(plotDim.yScale, true);
-    this.renderScale(plotDim.xScale);
-    this.dom.svg.append("line").attr("class", "sjpp-corr-volcano-divide-line").attr("stroke", "black").attr("stroke-dasharray", "5 4").attr("stroke-opacity", 0.4).attr("x1", plotDim.divideLine.x).attr("x2", plotDim.divideLine.x).attr("y1", plotDim.divideLine.y1).attr("y2", plotDim.divideLine.y2);
-    this.dom.svg.append("line").attr("class", "sjpp-corr-volcano-threshold-line").attr("stroke", "black").attr("stroke-dasharray", "5 4").attr("stroke-opacity", 0.4).attr("x1", plotDim.thresholdLine.x1).attr("x2", plotDim.thresholdLine.x2).attr("y1", plotDim.thresholdLine.y).attr("y2", plotDim.thresholdLine.y);
-  }
-  renderScale(scale, isLeft = false) {
-    const scaleG = this.dom.plot.append("g").attr("transform", `translate(${scale.x}, ${scale.y})`).transition().duration(this.duration).call(isLeft ? axisLeft(scale.scale) : axisBottom(scale.scale));
-    axisstyle({
-      axis: scaleG,
-      color: "black",
-      showline: true
-    });
-  }
-  renderLegend(legendData, settings, interactions, defaultMaxRadius, defaultMinRadius) {
-    const svg = this.dom.legend.attr("width", 400).attr("height", 400).style("display", "inline-block").style("vertical-align", "top").style("padding-top", "20px");
-    const startXPos = 20;
-    const startYPos = 20;
-    new LegendCircleReference({
-      g: svg.append("g").attr("transform", `translate(${startXPos}, ${startYPos})`),
-      inputMax: defaultMaxRadius,
-      inputMin: defaultMinRadius,
-      maxLabel: legendData.absMax,
-      maxRadius: settings.radiusMax,
-      minLabel: legendData.absMin,
-      minRadius: settings.radiusMin,
-      title: "Sample Size",
-      menu: {
-        minMaxLabel: "pixels",
-        callback: async (obj) => {
-          await interactions.changeRadius(obj);
-        }
-      }
-    });
-    if (legendData.skippedVariables.length > 0) {
-      const newYPos = startYPos + settings.radiusMax + 60;
-      let incrY = 30;
-      const skippedVariablesG = svg.append("g").attr("transform", `translate(${startXPos}, ${newYPos})`);
-      skippedVariablesG.append("text").style("font-weight", "bold").style("font-size", "0.8em").text("Skipped Variables");
-      for (const term of legendData.skippedVariables) {
-        skippedVariablesG.append("text").attr("transform", `translate(${startXPos}, ${incrY})`).style("font-size", "0.8em").text(term.label);
-        incrY += 20;
-      }
-    }
-  }
-};
-function renderVariables(self, settings, interactions) {
-  self.dom.plot.selectAll("circle").data(self.viewData.variableItems).enter().append("circle").attr("id", (item) => `sjpp-corr-volcano-circle-${item.label}`).attr("stroke", (item) => item.color).attr("fill", (item) => item.color).attr("fill-opacity", 0.5).attr("cx", (item) => item.previousX).attr("cy", (item) => item.previousY).attr("r", (item) => item.radius * 0.9).transition().duration(self.duration).attr("cx", (item) => item.x).attr("cy", (item) => item.y).attr("r", (item) => item.radius).each(function(item) {
-    const circle = select_default(this);
-    new ItemToolTip(item, circle, self.dom.tip, settings);
-    circle.on("click", () => {
-      interactions.launchSampleScatter(item);
-    });
-  });
-}
-
-// plots/corrVolcano/interactions/CorrVolcanoInteractions.ts
-var CorrVolcanoInteractions = class {
-  constructor(app, dom, id) {
-    this.app = app;
-    this.dom = dom;
-    this.id = id;
-    this.variableTwLst = [];
-  }
-  download() {
-    const svg = this.dom.svg.node();
-    to_svg(svg, `correlationVolcano`, { apply_dom_styles: true });
-  }
-  //If no featureTw is set, show the tree to select a feature
-  async showTree() {
-    this.dom.div.selectAll("*").remove();
-    await appInit({
-      vocabApi: this.app.vocabApi,
-      holder: this.dom.div,
-      state: this.app.getState(),
-      tree: {
-        click_term: (_term) => {
-          const term = _term.term || _term;
-          this.app.dispatch({
-            type: "plot_create",
-            config: {
-              chartType: "correlationVolcano",
-              featureTw: _term.term ? _term : { term }
-            }
-          });
-          this.app.dispatch({
-            type: "plot_delete",
-            id: this.id
-          });
-        }
-      }
-    });
-  }
-  //When clicking on dot, launch the sample scatter by gene and drug
-  launchSampleScatter(item) {
-    const config = this.app.getState();
-    const plot = config.plots.find((p) => p.id === this.id);
-    const term2 = this.variableTwLst?.find((t) => t.$id === item.tw$id)?.term;
-    if (!term2) throw `No term found for ${item.tw$id}`;
-    const scatterConfig = {
-      chartType: "sampleScatter",
-      name: `${plot.featureTw.term.name} ${termType2label(plot.featureTw.term.type)} v ${term2.name}`,
-      term: { term: plot.featureTw.term },
-      term2: { id: term2.id },
-      filter: config.termfilter.filter
-    };
-    this.app.dispatch({
-      type: "plot_create",
-      config: scatterConfig
-    });
-  }
-  //Obj is returned from LegendCircleReference callback
-  async changeRadius(obj) {
-    this.app.dispatch({
-      type: "plot_edit",
-      id: this.id,
-      config: {
-        settings: {
-          correlationVolcano: {
-            radiusMax: obj.max,
-            radiusMin: obj.min
-          }
-        }
-      }
-    });
-  }
-  clearDom() {
-    this.dom.error.style("padding", "").text("");
-    this.dom.plot.selectAll("*").remove();
-    this.dom.legend.selectAll("*").remove();
-    this.dom.svg.selectAll("line").remove();
-    this.dom.title.text("");
-    this.dom.yAxisLabel.text("");
-    this.dom.xAxisLabel.text("");
-  }
-};
-
-// plots/corrVolcano/CorrelationVolcano.ts
-var CorrelationVolcano = class _CorrelationVolcano extends PlotBase {
-  constructor(opts, api) {
-    super(opts, api);
-    /** Max radius user may enter in control or legend menu */
-    this.defaultInputMaxRadius = 35;
-    /** Min radius user may enter in control or legend menu */
-    this.defaultInputMinRadius = 1;
-    this.type = _CorrelationVolcano.type;
-    this.components = {
-      controls: {}
-    };
-    const holder = opts.holder.classed("sjpp-corrVolcano-main", true);
-    const controls = opts.controls ? holder : holder.append("div");
-    const div = holder.append("div").style("padding", "5px").style("display", "inline-block");
-    const errorDiv = div.append("div").attr("id", "sjpp-corrVolcano-error").style("opacity", 0.75);
-    const svg = div.append("svg").style("display", "inline-block").attr("id", "sjpp-corrVolcano-svg");
-    this.dom = {
-      controls: controls.style("display", "block"),
-      div,
-      error: errorDiv,
-      svg,
-      plot: svg.append("g"),
-      title: svg.append("text"),
-      yAxisLabel: svg.append("text"),
-      xAxisLabel: svg.append("text"),
-      legend: div.append("svg"),
-      tip: new Menu({ padding: "" })
-    };
-    if (opts.header) formatHeaderText({
-      header: opts.header,
-      chartType: "CORRELATION VOLCANO"
-    });
-    this.variableTwLst = [];
-  }
-  static {
-    this.type = "correlationVolcano";
-  }
-  getState(appState) {
-    const config = appState.plots.find((p) => p.id === this.id);
-    if (!config) {
-      throw `No plot with id='${this.id}' found. Did you set this.id before this.api = getComponentApi(this)?`;
-    }
-    return {
-      termdbConfig: appState.termdbConfig,
-      termfilter: appState.termfilter,
-      correlationVolcano: appState.termdbConfig.correlationVolcano,
-      config: Object.assign({}, config, {
-        settings: {
-          correlationVolcano: config.settings.correlationVolcano
-        }
-      })
-    };
-  }
-  async setControls() {
-    const inputs = [
-      {
-        type: "term",
-        configKey: "featureTw",
-        chartType: "correlationVolcano",
-        usecase: { target: "correlationVolcano", detail: "numeric" },
-        label: "Feature",
-        vocabApi: this.app.vocabApi,
-        numericEditMenuVersion: ["continuous"],
-        menuOptions: "replace"
-      },
-      {
-        label: "Correlation method",
-        title: "Change the correlation method",
-        type: "radio",
-        chartType: "correlationVolcano",
-        settingsKey: "method",
-        options: [
-          { label: "Pearson", value: "pearson" },
-          { label: "Spearman", value: "spearman" }
-        ]
-      },
-      {
-        label: "P value",
-        title: "Change the p value",
-        type: "radio",
-        chartType: "correlationVolcano",
-        settingsKey: "isAdjustedPValue",
-        options: [
-          { label: "Adjusted", value: true },
-          { label: "Original", value: false }
-        ]
-      },
-      {
-        label: "Significant p value",
-        title: "Set the significant p value threshold",
-        type: "number",
-        chartType: "correlationVolcano",
-        settingsKey: "threshold",
-        debounceInterval: 0.05
-      },
-      {
-        label: "Maximum radius size",
-        title: "Set maximum radius size in pixels",
-        type: "number",
-        chartType: "correlationVolcano",
-        settingsKey: "radiusMax",
-        min: this.defaultInputMinRadius,
-        max: this.defaultInputMaxRadius,
-        debounceInterval: 500
-      },
-      {
-        label: "Minimum radius size",
-        title: "Set minimum radius size in pixels",
-        type: "number",
-        chartType: "correlationVolcano",
-        settingsKey: "radiusMin",
-        min: this.defaultInputMinRadius,
-        max: this.defaultInputMaxRadius,
-        debounceInterval: 500
-      },
-      {
-        label: "Height",
-        title: "Set the height of the plot",
-        type: "number",
-        chartType: "correlationVolcano",
-        settingsKey: "height",
-        debounceInterval: 500
-      },
-      {
-        label: "Width",
-        title: "Set the width of the plot",
-        type: "number",
-        chartType: "correlationVolcano",
-        settingsKey: "width",
-        debounceInterval: 500
-      },
-      {
-        label: "Correlation color",
-        type: "color",
-        chartType: "correlationVolcano",
-        settingsKey: "corrColor",
-        title: "Color of correlated values"
-      },
-      {
-        label: "Anticorrelation color",
-        type: "color",
-        chartType: "correlationVolcano",
-        settingsKey: "antiCorrColor",
-        title: "Color of anticorrelated values"
-      }
-    ];
-    this.components.controls = await controlsInit({
-      app: this.app,
-      id: this.id,
-      holder: this.dom.controls.style("display", "inline-block"),
-      inputs
-    });
-    this.components.controls.on("downloadClick.correlationVolcano", () => {
-      this.interactions.download();
-    });
-    this.components.controls.on("helpClick.correlationVolcano", () => {
-      window.open("https://github.com/stjude/proteinpaint/wiki/Correlation-volcano", "_blank");
-    });
-  }
-  async init(appState) {
-    this.interactions = new CorrVolcanoInteractions(this.app, this.dom, this.id);
-    const state = this.getState(appState);
-    if (state.config["featureTw"]) await this.setControls();
-    const dsCorrVolcano = state.termdbConfig.correlationVolcano;
-    this.variableTwLst = dsCorrVolcano.variables.termIds.map((id) => {
-      return { id };
-    });
-    this.interactions.variableTwLst = this.variableTwLst;
-    await fillTwLst(this.variableTwLst, this.app.vocabApi);
-  }
-  async main() {
-    const config = structuredClone(this.state.config);
-    if (config.childType != this.type && config.chartType != this.type) return;
-    if (!this.interactions) throw "Interactions not initialized [correlationVolcano main()]";
-    if (config.featureTw == null) {
-      this.interactions.showTree();
-      return;
-    }
-    const settings = config.settings.correlationVolcano;
-    const model = new Model(config, this.state, this.app, settings, this.variableTwLst, this.vocabApi);
-    const data = await model.getData();
-    if (!data || data.error || !data.variableItems.length) {
-      this.interactions.clearDom();
-      this.dom.error.style("padding", "20px 20px 20px 60px").text(data.error || "No correlation data to render.");
-      return;
-    }
-    const viewModel = new ViewModel(config, data, this.dom, settings, this.variableTwLst);
-    new View(
-      this.dom,
-      viewModel.viewData,
-      this.interactions,
-      settings,
-      this.defaultInputMaxRadius,
-      this.defaultInputMinRadius
-    );
-  }
-};
-var corrVolcanoInit = getCompInit(CorrelationVolcano);
-var componentInit = corrVolcanoInit;
-function getDefaultCorrVolcanoSettings(overrides = {}) {
-  const defaults = {
-    antiCorrColor: "#ff0000",
-    //red
-    corrColor: "#0000ff",
-    //blue
-    isAdjustedPValue: false,
-    method: "pearson",
-    threshold: 0.05,
-    height: 500,
-    width: 500,
-    radiusMax: 20,
-    radiusMin: 5
-  };
-  return Object.assign(defaults, overrides);
-}
-async function getPlotConfig(opts, app) {
-  if (opts.numeric && !opts.featureTw) opts.featureTw = { term: opts.numeric.term };
-  if (opts.featureTw) {
-    try {
-      await fillTermWrapper(opts.featureTw, app.vocabApi);
-    } catch (e) {
-      console.error(new Error(`${e} [correlationVolcano getPlotConfig()]`));
-      throw `correlationVolcano getPlotConfig() failed`;
-    }
-  }
-  const config = {
-    chartType: "correlationVolcano",
-    featureTw: opts.featureTw ?? null,
-    settings: {
-      controls: {
-        term2: null,
-        term0: null
-      },
-      correlationVolcano: getDefaultCorrVolcanoSettings(opts.overrides || {})
-    }
-  };
-  return copyMerge(config, opts);
-}
-export {
-  componentInit,
-  corrVolcanoInit,
-  getDefaultCorrVolcanoSettings,
-  getPlotConfig
-};
-//# sourceMappingURL=CorrelationVolcano-33I4FC44.js.map