@sjcrh/proteinpaint-client 2.203.0 → 2.203.1
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/dist/2dmaf-6CEBP4SA.js +1366 -0
- package/dist/AIProjectAdmin-2CKKFC3A.js +951 -0
- package/dist/AggregateMatrix-5TBUMFE5.js +665 -0
- package/dist/AppHeader-5YBPWF44.js +829 -0
- package/dist/BoxPlot-UOJS5SJV.js +1210 -0
- package/dist/CorrelationVolcano-KX6JPZMT.js +613 -0
- package/dist/Cuminc-TLOOLZWR.js +1208 -0
- package/dist/DE-HUQLQ2Z3.js +87 -0
- package/dist/DEinput-WWUISAF2.js +404 -0
- package/dist/DifferentialAnalysis-6DTAGCEY.js +237 -0
- package/dist/Disco-P6ZLPYLF.js +3388 -0
- package/dist/Disco.UI-WGTMAFK2.js +242 -0
- package/dist/DmrPlot-3FRU5KUK.js +636 -0
- package/dist/GB-NWOBARL3.js +1390 -0
- package/dist/GSEA-DEEUAAMI.js +850 -0
- package/dist/GeneExpInput-6QWGEAFV.js +361 -0
- package/dist/Geomap-6HT2B7RH.js +83 -0
- package/dist/HicApp-PCNOUULF.js +2244 -0
- package/dist/IDCViewer-H3QPXVM3.js +10811 -0
- package/dist/NumBinaryEditor-IU6OLMKN.js +278 -0
- package/dist/NumBinaryEditor.unit.spec-YUPUILIV.js +311 -0
- package/dist/NumContEditor-KFDA76QN.js +104 -0
- package/dist/NumContEditor.unit.spec-QBOT5QHU.js +163 -0
- package/dist/NumCustomBinEditor-EOSTEXLB.js +32 -0
- package/dist/NumCustomBinEditor.unit.spec-B46XWFYH.js +396 -0
- package/dist/NumDiscreteEditor-Y4EAADXC.js +169 -0
- package/dist/NumDiscreteEditor.unit.spec-SJGHLWSM.js +232 -0
- package/dist/NumRegularBinEditor-3BNG7DIN.js +32 -0
- package/dist/NumRegularBinEditor.unit.spec-KM45QXXG.js +277 -0
- package/dist/NumSplineEditor-K4KPDC4S.js +209 -0
- package/dist/NumSplineEditor.unit.spec-TKQP5XTS.js +223 -0
- package/dist/NumericDensity-Z6JFVN3D.js +32 -0
- package/dist/NumericDensity.unit.spec-YEYBVLEP.js +417 -0
- package/dist/NumericHandler-ITT6HMPN.js +33 -0
- package/dist/NumericHandler.unit.spec-QVONMXY4.js +213 -0
- package/dist/ProteomeInput-PRS3DEMZ.js +387 -0
- package/dist/Regression-LJJJBBT6.js +1413 -0
- package/dist/Regression-LJJJBBT6.js.map +7 -0
- package/dist/RunChart2-AMM2JFF5.js +749 -0
- package/dist/SC-F7IE66VZ.js +1106 -0
- package/dist/Violin-RJ6OJZ4F.js +1073 -0
- package/dist/Volcano-BJA5HN5Y.js +1414 -0
- package/dist/WSIViewer-RJZGRUIR.js +26194 -0
- package/dist/Wsi-DXP6KOQA.js +232 -0
- package/dist/WsiSamplesPlot-2IAWV2B6.js +159 -0
- package/dist/adSandbox-RGWOIV3W.js +32 -0
- package/dist/animatedBubbleChart-J4Q2NAEW.js +546 -0
- package/dist/app-3QXNR4VG.js +31 -0
- package/dist/app-B4B7YNP3.js +41 -0
- package/dist/app.js +12 -12
- package/dist/bam-LRUMN45P.js +875 -0
- package/dist/barchart-L2G6GEHK.js +41 -0
- package/dist/barchart2-DWNVAZAJ.js +308 -0
- package/dist/block-TVEVAXNP.js +6248 -0
- package/dist/block.init-YOHAKPRI.js +32 -0
- package/dist/block.mds.expressionrank-PU6JH4W5.js +353 -0
- package/dist/block.mds.geneboxplot-WYYFDNE3.js +822 -0
- package/dist/block.mds.junction-4WCTL7Y4.js +1538 -0
- package/dist/block.mds.svcnv-MR3VCYUW.js +6795 -0
- package/dist/block.svg-LR3Y4ZO7.js +158 -0
- package/dist/block.tk.aicheck-A5AWKJZI.js +277 -0
- package/dist/block.tk.ase-AQBBAQEH.js +359 -0
- package/dist/block.tk.bam-QBTA2O3V.js +1900 -0
- package/dist/block.tk.bedgraphdot-4ALZG2MY.js +378 -0
- package/dist/block.tk.bigwig.ui-32W6XW37.js +205 -0
- package/dist/block.tk.hicstraw-PKBHBAG2.js +817 -0
- package/dist/block.tk.junction-AO5CXUCU.js +2357 -0
- package/dist/block.tk.junction.textmatrixui-RORVUIPI.js +193 -0
- package/dist/block.tk.ld-TNBSR4FT.js +93 -0
- package/dist/block.tk.menu-QDJO54J5.js +1023 -0
- package/dist/block.tk.pgv-6222WWYR.js +937 -0
- package/dist/brainImaging-2TPE7MXB.js +426 -0
- package/dist/brainImaging-2TPE7MXB.js.map +7 -0
- package/dist/brainRegions-KTFH6DE2.js +215 -0
- package/dist/bubbleHeatmap-LNXZLFY6.js +377 -0
- package/dist/cellTypeBubbleHeatmap-SRHUNX3S.js +277 -0
- package/dist/chunk-3TXVDBGN.js +626 -0
- package/dist/chunk-4HLHKBHP.js +274 -0
- package/dist/chunk-5GG7Q2ZG.js +397 -0
- package/dist/chunk-5HVAVJKW.js +518 -0
- package/dist/chunk-5HVAVJKW.js.map +7 -0
- package/dist/chunk-5PMFCQKC.js +98 -0
- package/dist/chunk-67URJYN7.js +84 -0
- package/dist/chunk-67URJYN7.js.map +7 -0
- package/dist/chunk-6AKSOLBX.js +5071 -0
- package/dist/chunk-6AKSOLBX.js.map +7 -0
- package/dist/chunk-6X7PP7A4.js +2126 -0
- package/dist/chunk-A3EDLRUN.js +54 -0
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- package/dist/chunk-EO6M3LY3.js +339 -0
- package/dist/chunk-EO6M3LY3.js.map +7 -0
- package/dist/chunk-F4PMOAQK.js +494 -0
- package/dist/chunk-FISQTHD4.js +2327 -0
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- package/dist/chunk-FXT2XM4E.js.map +7 -0
- package/dist/chunk-HIWTGMTE.js +1721 -0
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- package/dist/chunk-KLWSW6CC.js +203 -0
- package/dist/chunk-KNNSOOTG.js +194 -0
- package/dist/chunk-KTPXQH2N.js +170 -0
- package/dist/chunk-LGKXSWY4.js +276 -0
- package/dist/chunk-LP2GIXVK.js +4274 -0
- package/dist/chunk-M2ZZL5EV.js +2669 -0
- package/dist/chunk-M2ZZL5EV.js.map +7 -0
- package/dist/chunk-MBHERRJR.js +302 -0
- package/dist/chunk-MLYQDJUQ.js +480 -0
- package/dist/chunk-NBGDLLMX.js +446 -0
- package/dist/chunk-OPMMU6DQ.js +183 -0
- package/dist/chunk-OPMMU6DQ.js.map +7 -0
- package/dist/chunk-P3JEXVBT.js +50 -0
- package/dist/chunk-PZPPJY4K.js +34 -0
- package/dist/chunk-Q6JF4ZLT.js +141 -0
- package/dist/chunk-QF5IH7PC.js +263 -0
- package/dist/chunk-QJ6SO7CF.js +465 -0
- package/dist/chunk-QQUOVIOM.js +2899 -0
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- package/dist/chunk-SNCZRDS5.js +557 -0
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- package/dist/chunk-SPDNUC76.js +70 -0
- package/dist/chunk-T3663ZQL.js +37 -0
- package/dist/chunk-TSK4ZTFK.js +340 -0
- package/dist/chunk-USW6WRDZ.js +217 -0
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- package/dist/chunk-XE6E526E.js +129 -0
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- package/dist/chunk-YCECQV3T.js +160 -0
- package/dist/chunk-YROOKO3Q.js +1954 -0
- package/dist/chunk-YROOKO3Q.js.map +7 -0
- package/dist/chunk-Z4NADGZX.js +243 -0
- package/dist/chunk-Z53KOPRJ.js +102 -0
- package/dist/cohort-U7M6Q2UX.js +69 -0
- package/dist/condition-EGAV2PMJ.js +326 -0
- package/dist/controls-PTMYWUZV.js +33 -0
- package/dist/controls.config-DOA6PTP2.js +33 -0
- package/dist/correlation-Y3EL6GB7.js +94 -0
- package/dist/customdata.inputui-4NDDG6FL.js +283 -0
- package/dist/dataDownload-EQGUAOK2.js +328 -0
- package/dist/databrowser.ui-ABGOJUWQ.js +424 -0
- package/dist/dictionary-YOLLEDE5.js +112 -0
- package/dist/dnaMethylation-JZT63UHO.js +32 -0
- package/dist/dnaMethylation.integration.spec-EATCABJW.js +197 -0
- package/dist/dofetch-YNBIUFV5.js +48 -0
- package/dist/e2pca-RD6COCRL.js +343 -0
- package/dist/ep-BAI7WUET.js +1248 -0
- package/dist/expclust.gdc.spec-LKV2CQA5.js +301 -0
- package/dist/facet-X3SXQIAC.js +518 -0
- package/dist/gb-K324K7XB.js +80 -0
- package/dist/geneExpClustering-BJD5U3KG.js +243 -0
- package/dist/geneExpression-2TK3XLZ5.js +310 -0
- package/dist/geneExpression-F6NRTHZ4.js +32 -0
- package/dist/geneExpression.unit.spec-IFZN3J6A.js +96 -0
- package/dist/geneORA-DUEP735U.js +272 -0
- package/dist/geneRanking-LURDNT7L.js +547 -0
- package/dist/geneVariant-EAVCWQAZ.js +35 -0
- package/dist/geneVariant-IZTFYAG6.js +284 -0
- package/dist/geneVariant-IZTFYAG6.js.map +7 -0
- package/dist/geneVariant.integration.spec-LHL4ERFO.js +192 -0
- package/dist/genefusion.ui-4T5R7DT7.js +302 -0
- package/dist/geneset-3PWXPBG2.js +202 -0
- package/dist/genomeBrowser.spec-5SEN7R2P.js +275 -0
- package/dist/grin2-EXBG7TMS.js +1136 -0
- package/dist/grin2-XIXVFVWO.js +69 -0
- package/dist/hierCluster-5XQIWXAY.js +57 -0
- package/dist/hierCluster-I4TAQWPF.js +53 -0
- package/dist/hierCluster.config-T7HVAWES.js +34 -0
- package/dist/hierCluster.integration.spec-XWX43K4D.js +482 -0
- package/dist/hierCluster.interactivity-MYIDHFSL.js +48 -0
- package/dist/hierCluster.renderers-YRXA5ZUK.js +19 -0
- package/dist/imagePlot-4JQB6JUG.js +155 -0
- package/dist/importPlot-D3MXCCLN.js +8 -0
- package/dist/isoformExpression-WNGGUVIZ.js +34 -0
- package/dist/isoformExpression.unit.spec-NVJ5TIKM.js +236 -0
- package/dist/junction-O7N57JE3.js +35 -0
- package/dist/junction.unit.spec-Z63DRTRR.js +181 -0
- package/dist/launch.adhoc-MBDRXD3B.js +36 -0
- package/dist/leftlabel.sample-IG6FOQ26.js +257 -0
- package/dist/lollipop-ZUYBLPGN.js +165 -0
- package/dist/maf-QOS5LURG.js +454 -0
- package/dist/maftimeline-FEHP2J55.js +586 -0
- package/dist/matrix-BG4J4RXA.js +57 -0
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- package/dist/matrix.cells-PTIDQVCI.js +26 -0
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- package/dist/matrix.data-FMIQRXOA.js +23 -0
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- package/dist/multivalue-OZALSBFW.js +82 -0
- package/dist/numericDictTermCluster-7PGJ7KV4.js +63 -0
- package/dist/oncomatrix-Q2EQZPLS.js +289 -0
- package/dist/oncomatrix.spec-YEQOQRPW.js +442 -0
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- package/dist/plot.app-AEUR6XGI.js +35 -0
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- package/dist/plot.disco-LUFC5GGC.js +99 -0
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- package/dist/polar2-AB6SVYRS.js +231 -0
- package/dist/profileForms-AIEHZ4GC.js +933 -0
- package/dist/profilePlot-PZDFGXKZ.js +48 -0
- package/dist/proteinView-7GWHQYXC.js +1561 -0
- package/dist/proteomeCohortCompare-BTN4HHFL.js +779 -0
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- package/dist/singleCellCellType-EZYESBVZ.js +32 -0
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// plots/studyCatalog.ts
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var PTM_PROTEOMES = /* @__PURE__ */ new Set(["Phospho", "Ubiquitin"]);
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disease: {
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brainRegion: {
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var PANEL_GAP = 24;
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var FACET_WIDTH = 210;
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var StudyCatalog = class _StudyCatalog extends PlotBase {
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constructor(opts, api) {
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super(opts, api);
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/** active filter values per facet key; empty set (or absent) = no filter on that facet */
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this.activeFilters = /* @__PURE__ */ new Map();
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/** derived rows, one per cohort */
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/** number of cohorts currently passing the filters (shown when nothing is selected) */
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static {
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this.type = "studyCatalog";
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async init() {
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const holder = this.opts.holder.append("div").style("padding", "10px");
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holder,
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body,
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rightDiv: void 0,
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countSpan: void 0,
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tableDiv: void 0,
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tip: new Menu({ padding: "" }),
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header: this.opts.header
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getState(appState) {
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const config = appState.plots.find((p) => p.id === this.id);
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async main() {
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const proteome = this.app.vocabApi.termdbConfig?.queries?.proteome;
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const ui = proteome?.studyCatalog;
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this.dom.body.selectAll("*").remove();
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this.dom.body.append("div").style("padding", "20px").style("color", "#666").text("No study catalog is configured.");
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this.rows = this.deriveRows(proteome.organisms);
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this.dom.body.append("div").style("padding", "20px").style("color", "#666").text("No cohorts found.");
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const topBar = this.dom.body.append("div").style("display", "flex").style("align-items", "center").style("gap", "12px").style("margin-bottom", "8px").style("padding-left", `${FACET_WIDTH + PANEL_GAP}px`);
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this.dom.actionBtn = topBar.append("button").attr("class", "sjpp_apply_btn sja_sharp_border").property("disabled", true).text("Analyze Cohort").on("click", () => this.onAction());
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this.dom.countSpan = topBar.append("span").style("font-size", "0.85em").style("color", "#555");
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const layout = this.dom.body.append("div").style("display", "flex").style("gap", `${PANEL_GAP}px`);
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this.dom.facetsDiv = layout.append("div").style("flex", `0 0 ${FACET_WIDTH}px`).style("box-sizing", "border-box").style("max-height", "60vh").style("overflow-y", "auto").style("border-right", "1px solid #eee").style("padding-right", "12px");
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this.dom.rightDiv = layout.append("div").style("flex", "1 1 auto").style("min-width", "0");
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this.renderFacets(ui);
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this.renderTable(ui);
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}
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/** one row per organism→assay→cohort. `species` and `proteome` are derived from the query
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* structure (organism key + the assay's proteomeLabel); every other display field comes from
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* the cohort's `catalog` object in the dataset. A `catalog` key can still override either. */
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deriveRows(organisms) {
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for (const organism in organisms) {
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const species = organism.charAt(0).toUpperCase() + organism.slice(1);
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const assays = organisms[organism].assays || {};
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for (const assay in assays) {
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const proteome = assays[assay].proteomeLabel || assay;
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const cohorts = assays[assay].cohorts || {};
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for (const cohort in cohorts) {
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rows.push({ species, proteome, ...cohorts[cohort].catalog || {}, organism, assay, cohort });
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}
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/** rows passing every active filter, optionally excluding one facet (for that facet's own counts) */
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filteredRows(excludeFacet) {
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facetLabel(ui, key) {
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renderFacets(ui) {
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const queries = this.app.vocabApi.termdbConfig?.queries;
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header.append("span").style("font-weight", "bold").text("Filter by");
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header.append("span").style("margin-left", "auto").style("font-size", "0.8em").style("color", anyActive ? "#0a5" : "#aaa").style("cursor", anyActive ? "pointer" : "default").text("clear all").on("click", () => {
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openCompare(selected) {
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}
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};
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var componentInit = getCompInit(StudyCatalog);
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async function getPlotConfig(opts) {
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export {
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};
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//# sourceMappingURL=studyCatalog-BJTJJGBC.js.map
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@@ -1,7 +0,0 @@
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{
|
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|
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"version": 3,
|
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|
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"sources": ["../plots/studyCatalog.ts"],
|
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|
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"sourcesContent": ["import type { MassState, BasePlotConfig } from '#mass/types/mass'\nimport { getCompInit, copyMerge, type RxComponent, type ComponentApi } from '#rx'\nimport { PlotBase } from './PlotBase'\nimport { Menu, renderTable, addGeneSearchbox } from '#dom'\nimport type { TableColumn, TableRow } from '#dom'\n\n/** PTM proteome layers \u2014 kept separate from protein-level (Whole/Insoluble) layers because\n * PTM z is site-level collapsed to gene, so the two aren't directly comparable in a scatter/heatmap */\nconst PTM_PROTEOMES = new Set(['Phospho', 'Ubiquitin'])\n\n/** facets that get a \"launch chart\" button. needsGene=false charts launch directly (no gene\n * picker); gene-centric charts prompt for a gene first. `requires(queries)` gates the button on\n * the dataset config that chart needs, so it only shows where the chart can actually run. */\nconst FACET_CHART: Record<\n\tstring,\n\t{ chartType: string; label: string; needsGene: boolean; requires: (q: any) => boolean }\n> = {\n\tdisease: {\n\t\tchartType: 'animatedBubbleChart',\n\t\tlabel: 'Bubble Chart',\n\t\tneedsGene: false,\n\t\trequires: q => !!q?.geneRanking\n\t},\n\tcellType: {\n\t\tchartType: 'cellTypeBubbleHeatmap',\n\t\tlabel: 'Cell-type Bubble Heatmap',\n\t\tneedsGene: true,\n\t\trequires: q => !!q?.proteome?.cellTypeBubbleHeatmap\n\t},\n\tbrainRegion: {\n\t\tchartType: 'brainRegions',\n\t\tlabel: 'Brain Regional Proteome',\n\t\tneedsGene: true,\n\t\trequires: q => !!q?.proteome?.brainRegions\n\t}\n}\n\nconst defaultConfig = {\n\tchartType: 'studyCatalog'\n}\n\ntype CatalogColumn = { key: string; label: string }\ntype CatalogUiConfig = {\n\tcolumns: CatalogColumn[]\n\tfacets: string[]\n}\ntype CatalogRow = { [key: string]: string } & { organism: string; assay: string; cohort: string }\n\nconst PANEL_GAP = 24\nconst FACET_WIDTH = 210\n\nclass StudyCatalog extends PlotBase implements RxComponent {\n\tstatic type = 'studyCatalog'\n\ttype: string\n\tdom!: {\n\t\tholder: any\n\t\tbody: any\n\t\tfacetsDiv: any\n\t\trightDiv: any\n\t\tactionBtn: any\n\t\tcountSpan: any\n\t\ttableDiv: any\n\t\ttip: Menu\n\t\theader?: any\n\t}\n\t/** active filter values per facet key; empty set (or absent) = no filter on that facet */\n\tactiveFilters: Map<string, Set<string>> = new Map()\n\t/** derived rows, one per cohort */\n\trows: CatalogRow[] = []\n\t/** currently checked rows */\n\tselected: CatalogRow[] = []\n\t/** stable keys of the checked cohorts, so selection survives a table re-render */\n\tselectedKeys: Set<string> = new Set()\n\t/** number of cohorts currently passing the filters (shown when nothing is selected) */\n\tfilteredCount = 0\n\n\tconstructor(opts: any, api: ComponentApi) {\n\t\tsuper(opts, api)\n\t\tthis.type = StudyCatalog.type\n\t}\n\n\tasync init() {\n\t\tconst holder = this.opts.holder.append('div').style('padding', '10px')\n\t\tconst body = holder.append('div')\n\t\tthis.dom = {\n\t\t\tholder,\n\t\t\tbody,\n\t\t\tfacetsDiv: undefined,\n\t\t\trightDiv: undefined,\n\t\t\tactionBtn: undefined,\n\t\t\tcountSpan: undefined,\n\t\t\ttableDiv: undefined,\n\t\t\ttip: new Menu({ padding: '' }),\n\t\t\theader: this.opts.header\n\t\t}\n\t\tif (this.dom.header) this.dom.header.html('Sample Sets')\n\t}\n\n\tgetState(appState: MassState) {\n\t\tconst config: any = appState.plots.find((p: BasePlotConfig) => p.id === this.id)\n\t\tif (!config) throw `No plot with id='${this.id}' found`\n\t\treturn { config }\n\t}\n\n\tasync main() {\n\t\tconst proteome = this.app.vocabApi.termdbConfig?.queries?.proteome\n\t\tconst ui: CatalogUiConfig | undefined = proteome?.studyCatalog\n\t\tthis.dom.body.selectAll('*').remove()\n\t\tif (!ui || !proteome?.organisms) {\n\t\t\tthis.dom.body\n\t\t\t\t.append('div')\n\t\t\t\t.style('padding', '20px')\n\t\t\t\t.style('color', '#666')\n\t\t\t\t.text('No study catalog is configured.')\n\t\t\treturn\n\t\t}\n\n\t\tthis.rows = this.deriveRows(proteome.organisms)\n\t\tif (!this.rows.length) {\n\t\t\tthis.dom.body.append('div').style('padding', '20px').style('color', '#666').text('No cohorts found.')\n\t\t\treturn\n\t\t}\n\n\t\t// top bar (above facets + table): action button + count, indented so they line up with\n\t\t// the table's left edge (its line-number column), not with the filter rail\n\t\tconst topBar = this.dom.body\n\t\t\t.append('div')\n\t\t\t.style('display', 'flex')\n\t\t\t.style('align-items', 'center')\n\t\t\t.style('gap', '12px')\n\t\t\t.style('margin-bottom', '8px')\n\t\t\t.style('padding-left', `${FACET_WIDTH + PANEL_GAP}px`)\n\t\tthis.dom.actionBtn = topBar\n\t\t\t.append('button')\n\t\t\t.attr('class', 'sjpp_apply_btn sja_sharp_border')\n\t\t\t.property('disabled', true)\n\t\t\t.text('Analyze Cohort')\n\t\t\t.on('click', () => this.onAction())\n\t\tthis.dom.countSpan = topBar.append('span').style('font-size', '0.85em').style('color', '#555')\n\n\t\tconst layout = this.dom.body.append('div').style('display', 'flex').style('gap', `${PANEL_GAP}px`)\n\n\t\t// left rail \u2014 filters; border-box so its total width is exactly FACET_WIDTH (keeps the\n\t\t// button/table alignment above), capped to the table's height so the two line up\n\t\tthis.dom.facetsDiv = layout\n\t\t\t.append('div')\n\t\t\t.style('flex', `0 0 ${FACET_WIDTH}px`)\n\t\t\t.style('box-sizing', 'border-box')\n\t\t\t.style('max-height', '60vh')\n\t\t\t.style('overflow-y', 'auto')\n\t\t\t.style('border-right', '1px solid #eee')\n\t\t\t.style('padding-right', '12px')\n\n\t\t// right \u2014 table\n\t\tthis.dom.rightDiv = layout.append('div').style('flex', '1 1 auto').style('min-width', '0')\n\t\tthis.dom.tableDiv = this.dom.rightDiv.append('div')\n\n\t\tthis.renderFacets(ui)\n\t\tthis.renderTable(ui)\n\t}\n\n\t/** one row per organism\u2192assay\u2192cohort. `species` and `proteome` are derived from the query\n\t * structure (organism key + the assay's proteomeLabel); every other display field comes from\n\t * the cohort's `catalog` object in the dataset. A `catalog` key can still override either. */\n\tderiveRows(organisms: any): CatalogRow[] {\n\t\tconst rows: CatalogRow[] = []\n\t\tfor (const organism in organisms) {\n\t\t\tconst species = organism.charAt(0).toUpperCase() + organism.slice(1)\n\t\t\tconst assays = organisms[organism].assays || {}\n\t\t\tfor (const assay in assays) {\n\t\t\t\tconst proteome = assays[assay].proteomeLabel || assay\n\t\t\t\tconst cohorts = assays[assay].cohorts || {}\n\t\t\t\tfor (const cohort in cohorts) {\n\t\t\t\t\t// species/proteome first so catalog may override them; identity keys last so it can't\n\t\t\t\t\trows.push({ species, proteome, ...(cohorts[cohort].catalog || {}), organism, assay, cohort } as CatalogRow)\n\t\t\t\t}\n\t\t\t}\n\t\t}\n\t\treturn rows\n\t}\n\n\t/** rows passing every active filter, optionally excluding one facet (for that facet's own counts) */\n\tfilteredRows(excludeFacet?: string): CatalogRow[] {\n\t\treturn this.rows.filter(row => {\n\t\t\tfor (const [facet, values] of this.activeFilters) {\n\t\t\t\tif (facet === excludeFacet) continue\n\t\t\t\tif (values.size === 0) continue\n\t\t\t\tif (!values.has(row[facet] || '')) return false\n\t\t\t}\n\t\t\treturn true\n\t\t})\n\t}\n\n\tfacetLabel(ui: CatalogUiConfig, key: string): string {\n\t\treturn ui.columns.find(c => c.key === key)?.label || key\n\t}\n\n\trenderFacets(ui: CatalogUiConfig) {\n\t\tconst div = this.dom.facetsDiv\n\t\tdiv.selectAll('*').remove()\n\n\t\t// dataset query config, used to gate each facet's chart button on what the chart needs\n\t\tconst queries = this.app.vocabApi.termdbConfig?.queries\n\n\t\tconst header = div\n\t\t\t.append('div')\n\t\t\t.style('display', 'flex')\n\t\t\t.style('align-items', 'center')\n\t\t\t.style('margin-bottom', '8px')\n\t\theader.append('span').style('font-weight', 'bold').text('Filter by')\n\t\tconst anyActive = [...this.activeFilters.values()].some(s => s.size > 0)\n\t\theader\n\t\t\t.append('span')\n\t\t\t.style('margin-left', 'auto')\n\t\t\t.style('font-size', '0.8em')\n\t\t\t.style('color', anyActive ? '#0a5' : '#aaa')\n\t\t\t.style('cursor', anyActive ? 'pointer' : 'default')\n\t\t\t.text('clear all')\n\t\t\t.on('click', () => {\n\t\t\t\tif (!anyActive) return\n\t\t\t\tthis.activeFilters.clear()\n\t\t\t\tthis.renderFacets(ui)\n\t\t\t\tthis.renderTable(ui)\n\t\t\t})\n\n\t\tfor (const facet of ui.facets) {\n\t\t\t// counts reflect all OTHER active filters (standard faceted behavior)\n\t\t\tconst scope = this.filteredRows(facet)\n\t\t\tconst counts = new Map<string, number>()\n\t\t\tfor (const row of scope) {\n\t\t\t\tconst v = row[facet] || ''\n\t\t\t\tif (!v) continue\n\t\t\t\tcounts.set(v, (counts.get(v) || 0) + 1)\n\t\t\t}\n\t\t\tif (counts.size === 0) continue\n\n\t\t\tconst group = div.append('div').style('margin-bottom', '12px')\n\t\t\tconst titleRow = group\n\t\t\t\t.append('div')\n\t\t\t\t.style('display', 'flex')\n\t\t\t\t.style('align-items', 'center')\n\t\t\t\t.style('gap', '6px')\n\t\t\t\t.style('margin-bottom', '4px')\n\t\t\ttitleRow.append('span').style('font-weight', '600').style('font-size', '0.9em').text(this.facetLabel(ui, facet))\n\t\t\t// some facets get a button that launches a related chart \u2014 only if the dataset supports it\n\t\t\tconst chart = FACET_CHART[facet]\n\t\t\tif (chart && chart.requires(queries)) {\n\t\t\t\ttitleRow\n\t\t\t\t\t.append('button')\n\t\t\t\t\t.attr('class', 'sja_menuoption sja_sharp_border')\n\t\t\t\t\t.style('font-size', '0.72em')\n\t\t\t\t\t.style('padding', '1px 5px')\n\t\t\t\t\t.style('cursor', 'pointer')\n\t\t\t\t\t.attr('title', `Open ${chart.label}`)\n\t\t\t\t\t.text('\uD83D\uDCCA')\n\t\t\t\t\t.on('click', (event: any) => this.openChartMenu(chart, event))\n\t\t\t}\n\n\t\t\tconst active = this.activeFilters.get(facet) || new Set<string>()\n\t\t\tconst values = [...counts.keys()].sort((a, b) => a.localeCompare(b, undefined, { numeric: true }))\n\t\t\tfor (const value of values) {\n\t\t\t\tconst line = group\n\t\t\t\t\t.append('label')\n\t\t\t\t\t.style('display', 'flex')\n\t\t\t\t\t.style('align-items', 'center')\n\t\t\t\t\t.style('gap', '6px')\n\t\t\t\t\t.style('font-size', '0.85em')\n\t\t\t\t\t.style('cursor', 'pointer')\n\t\t\t\t\t.style('padding', '1px 0')\n\t\t\t\tline\n\t\t\t\t\t.append('input')\n\t\t\t\t\t.attr('type', 'checkbox')\n\t\t\t\t\t.property('checked', active.has(value))\n\t\t\t\t\t.on('change', (event: any) => {\n\t\t\t\t\t\tconst set = this.activeFilters.get(facet) || new Set<string>()\n\t\t\t\t\t\tif (event.target.checked) set.add(value)\n\t\t\t\t\t\telse set.delete(value)\n\t\t\t\t\t\tif (set.size) this.activeFilters.set(facet, set)\n\t\t\t\t\t\telse this.activeFilters.delete(facet)\n\t\t\t\t\t\tthis.renderFacets(ui)\n\t\t\t\t\t\tthis.renderTable(ui)\n\t\t\t\t\t})\n\t\t\t\tline.append('span').style('flex', '1 1 auto').text(value)\n\t\t\t\tline.append('span').style('color', '#999').text(counts.get(value)!)\n\t\t\t}\n\t\t}\n\t}\n\n\trenderTable(ui: CatalogUiConfig) {\n\t\tconst rows = this.filteredRows()\n\t\tthis.filteredCount = rows.length\n\t\tthis.dom.tableDiv.selectAll('*').remove()\n\t\tthis.dom.tableDiv.style('font-size', '13px')\n\n\t\t// preserve selection across re-renders (rx main() rebuilds the table): preselect the\n\t\t// still-visible rows whose cohort is selected, and prune keys that got filtered out\n\t\tconst selectedRows: number[] = []\n\t\trows.forEach((r, i) => {\n\t\t\tif (this.selectedKeys.has(this.cohortKey(r))) selectedRows.push(i)\n\t\t})\n\t\tthis.selected = selectedRows.map(i => rows[i])\n\t\tthis.selectedKeys = new Set(this.selected.map(r => this.cohortKey(r)))\n\t\tthis.updateActionBtn()\n\n\t\tconst columns: TableColumn[] = ui.columns.map(c => ({ label: c.label, sortable: true }))\n\t\tconst tableRows: TableRow[] = rows.map(row => ui.columns.map(c => ({ value: row[c.key] ?? '' })) as TableRow)\n\n\t\trenderTable({\n\t\t\tcolumns,\n\t\t\trows: tableRows,\n\t\t\tdiv: this.dom.tableDiv,\n\t\t\tshowLines: true,\n\t\t\tstriped: true,\n\t\t\tmaxHeight: '60vh',\n\t\t\tmaxWidth: '72vw',\n\t\t\tresize: true,\n\t\t\tselectedRows,\n\t\t\theader: { allowSort: true, style: { 'font-weight': 'bold', color: '#000' } },\n\t\t\tbuttons: [\n\t\t\t\t{\n\t\t\t\t\ttext: 'select',\n\t\t\t\t\tcallback: () => {},\n\t\t\t\t\tonChange: (idxs: number[], button: any) => {\n\t\t\t\t\t\tbutton.style.display = 'none'\n\t\t\t\t\t\tlet sel = idxs.map(i => rows[i])\n\t\t\t\t\t\tif (sel.length > 1) {\n\t\t\t\t\t\t\tconst cls = this.proteomeClass(sel[0])\n\t\t\t\t\t\t\tconst offIdx = new Set(idxs.filter(i => this.proteomeClass(rows[i]) !== cls))\n\t\t\t\t\t\t\tif (offIdx.size) {\n\t\t\t\t\t\t\t\tsel = idxs.filter(i => !offIdx.has(i)).map(i => rows[i])\n\t\t\t\t\t\t\t\tconst nodes = this.dom.tableDiv.selectAll('tbody input[type=\"checkbox\"]').nodes() as HTMLInputElement[]\n\t\t\t\t\t\t\t\tfor (const node of nodes) if (offIdx.has(Number(node.getAttribute('value')))) node.checked = false\n\t\t\t\t\t\t\t}\n\t\t\t\t\t\t}\n\t\t\t\t\t\tthis.selected = sel\n\t\t\t\t\t\tthis.selectedKeys = new Set(sel.map(r => this.cohortKey(r)))\n\t\t\t\t\t\tthis.updateActionBtn()\n\t\t\t\t\t\tthis.applyClassLock(rows)\n\t\t\t\t\t}\n\t\t\t\t}\n\t\t\t]\n\t\t})\n\t}\n\n\t/** stable identity of a cohort row, used to keep the selection across re-renders */\n\tcohortKey(row: CatalogRow): string {\n\t\treturn `${row.organism}|${row.assay}|${row.cohort}`\n\t}\n\n\t/** PTM (site-level) vs non-PTM (protein-level) class of a cohort row */\n\tproteomeClass(row: CatalogRow): 'ptm' | 'nonptm' {\n\t\treturn PTM_PROTEOMES.has(row.proteome) ? 'ptm' : 'nonptm'\n\t}\n\n\t/** PTM/non-PTM lock: once a cohort is selected, disable + dim checkboxes\n\t * for cohorts of the OTHER class. */\n\tapplyClassLock(rows: CatalogRow[]) {\n\t\tconst locked = this.selected.length ? this.proteomeClass(this.selected[0]) : null\n\t\tconst nodes = this.dom.tableDiv.selectAll('tbody input[type=\"checkbox\"]').nodes() as HTMLInputElement[]\n\t\tfor (const input of nodes) {\n\t\t\tconst vAttr = input.getAttribute('value')\n\t\t\tif (vAttr === null) continue\n\t\t\tconst idx = Number(vAttr)\n\t\t\tif (!Number.isInteger(idx) || idx < 0 || idx >= rows.length) continue\n\t\t\tconst disable = locked !== null && !input.checked && this.proteomeClass(rows[idx]) !== locked\n\t\t\tinput.disabled = disable\n\t\t\tconst tr = input.closest('tr') as HTMLElement | null\n\t\t\tif (tr) tr.style.opacity = disable ? '0.4' : ''\n\t\t}\n\t}\n\n\t/** update the action button + count text from the current selection.\n\t * count: nothing selected \u2192 total filtered cohorts; 1 selected \u2192 hidden; \u22652 \u2192 selected count */\n\tupdateActionBtn() {\n\t\tconst btn = this.dom.actionBtn\n\t\tif (!btn) return\n\t\tconst n = this.selected.length\n\t\tbtn.property('disabled', n === 0).text(n >= 2 ? 'Compare cohorts' : 'Analyze Cohort')\n\t\tconst cs = this.dom.countSpan\n\t\tif (n === 1) cs.style('display', 'none')\n\t\telse if (n >= 2) cs.style('display', '').text(`${n} cohorts`)\n\t\telse cs.style('display', '').text(`${this.filteredCount} cohort${this.filteredCount === 1 ? '' : 's'}`)\n\t}\n\n\t/** run the action for the current selection: 1 cohort \u2192 Analyze; \u22652 \u2192 Compare */\n\tonAction() {\n\t\tconst sel = this.selected\n\t\tif (sel.length === 1) this.openAnalyticsTools(sel[0])\n\t\telse if (sel.length >= 2) this.openCompare(sel)\n\t}\n\n\t/** launch a facet's chart. Charts that don't need a gene open directly; gene-centric ones\n\t * prompt for a gene first. Dispatches exactly chart.chartType (no importPlot indirection). */\n\topenChartMenu(chart: { chartType: string; needsGene: boolean }, event: any) {\n\t\tif (!chart.needsGene) {\n\t\t\tthis.app.dispatch({ type: 'plot_create', config: { chartType: chart.chartType } })\n\t\t\treturn\n\t\t}\n\t\tthis.dom.tip.clear().show(event.clientX, event.clientY)\n\t\tconst row = this.dom.tip.d.append('div').style('padding', '5px')\n\t\trow.append('span').style('font-weight', 'bold').text('Enter a gene name:')\n\t\tconst geneSearch = addGeneSearchbox({\n\t\t\trow,\n\t\t\tgenome: this.app.opts.genome,\n\t\t\ttip: new Menu({ padding: '0px' }),\n\t\t\tsearchOnly: 'gene',\n\t\t\tcallback: () => {\n\t\t\t\tif (!geneSearch.geneSymbol) throw new Error('A valid gene selection is required')\n\t\t\t\tthis.dom.tip.hide()\n\t\t\t\tthis.app.dispatch({ type: 'plot_create', config: { chartType: chart.chartType, gene: geneSearch.geneSymbol } })\n\t\t\t}\n\t\t})\n\t}\n\n\t/** open the ProteomeInput \"Analytics Tools\" panel for a cohort, mirroring the\n\t * Sample Selection (proteomeAbundance) chart's \"Analytics Tools\" button */\n\topenAnalyticsTools(row: CatalogRow) {\n\t\tthis.app.dispatch({\n\t\t\ttype: 'plot_create',\n\t\t\tconfig: {\n\t\t\t\tchartType: 'ProteomeInput',\n\t\t\t\tproteomeDetails: { organism: row.organism, assay: row.assay, cohort: row.cohort },\n\t\t\t\thidePlotFilter: true\n\t\t\t}\n\t\t})\n\t}\n\n\t/** open the cross-cohort log2FC-z comparison for the selected cohorts */\n\topenCompare(selected: CatalogRow[]) {\n\t\tthis.app.dispatch({\n\t\t\ttype: 'plot_create',\n\t\t\tconfig: {\n\t\t\t\tchartType: 'proteomeCohortCompare',\n\t\t\t\tcohorts: selected.map(r => ({ organism: r.organism, assay: r.assay, cohort: r.cohort, label: r.cohort })),\n\t\t\t\tcrossSpecies: false\n\t\t\t}\n\t\t})\n\t}\n}\n\nexport const componentInit = getCompInit(StudyCatalog)\n\nexport async function getPlotConfig(opts: any) {\n\tconst config = structuredClone(defaultConfig)\n\treturn copyMerge(config, opts)\n}\n"],
|
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5
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-
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import {
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launchPlot
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make_one_checkbox,
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// plots/summarizeCnvGeneexp.ts
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var tip = new Menu({ padding: "0px" });
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async function makeChartBtnMenu(holder, chartsInstance) {
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let expTw, cnvTw, cnvGeneSameAsExp = true, expSearchPrompt, cnvTableRow;
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make_one_checkbox({
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|
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holder: holder.append("div").style("margin", "20px 10px 5px 15px"),
|
|
47
|
-
labeltext: "Use Same Gene For CNV",
|
|
48
|
-
checked: true,
|
|
49
|
-
testid: "sjpp-summarizeCnvGeneexp-useSameGeneCheckbox",
|
|
50
|
-
callback: async (checked) => {
|
|
51
|
-
cnvGeneSameAsExp = checked;
|
|
52
|
-
await updateUi();
|
|
53
|
-
}
|
|
54
|
-
});
|
|
55
|
-
const table = table2col({
|
|
56
|
-
holder: holder.append("div"),
|
|
57
|
-
margin: "10px",
|
|
58
|
-
cellPadding: "10px"
|
|
59
|
-
});
|
|
60
|
-
{
|
|
61
|
-
const [td1, td2] = table.addRow();
|
|
62
|
-
td1.text("Search Gene For Expression");
|
|
63
|
-
const searchDiv = td2.append("div");
|
|
64
|
-
expSearchPrompt = td2.append("div").style("font-size", ".7em");
|
|
65
|
-
const result = addGeneSearchbox({
|
|
66
|
-
row: searchDiv,
|
|
67
|
-
tip,
|
|
68
|
-
searchOnly: "gene",
|
|
69
|
-
testid: "sjpp-summarizeCnvGeneexp-genesearch-exp",
|
|
70
|
-
genome: chartsInstance.app.opts.genome,
|
|
71
|
-
callback: async () => {
|
|
72
|
-
expSearchPrompt.text("LOADING ...");
|
|
73
|
-
try {
|
|
74
|
-
expTw = { term: { gene: result.geneSymbol, type: "geneExpression" }, q: {} };
|
|
75
|
-
await updateUi();
|
|
76
|
-
if (cnvGeneSameAsExp) launch();
|
|
77
|
-
expSearchPrompt.text("");
|
|
78
|
-
} catch (e) {
|
|
79
|
-
expSearchPrompt.text("Error: " + (e.message || e));
|
|
80
|
-
console.log(e.stack);
|
|
81
|
-
}
|
|
82
|
-
}
|
|
83
|
-
});
|
|
84
|
-
}
|
|
85
|
-
{
|
|
86
|
-
const [td1, td2] = table.addRow();
|
|
87
|
-
cnvTableRow = select_default(td1.node().parentNode);
|
|
88
|
-
td1.text("Search Gene for CNV");
|
|
89
|
-
const searchDiv = td2.append("div");
|
|
90
|
-
const cnvSearchPrompt = td2.append("div").style("font-size", ".7em");
|
|
91
|
-
const result = addGeneSearchbox({
|
|
92
|
-
row: searchDiv,
|
|
93
|
-
tip,
|
|
94
|
-
searchOnly: "gene",
|
|
95
|
-
testid: "sjpp-summarizeCnvGeneexp-genesearch-cnv",
|
|
96
|
-
genome: chartsInstance.app.opts.genome,
|
|
97
|
-
callback: async () => {
|
|
98
|
-
cnvSearchPrompt.text("LOADING ...");
|
|
99
|
-
try {
|
|
100
|
-
cnvTw = await fillGvTw(result.geneSymbol, dtcnv);
|
|
101
|
-
await updateUi();
|
|
102
|
-
cnvSearchPrompt.text("");
|
|
103
|
-
} catch (e) {
|
|
104
|
-
cnvSearchPrompt.text("Error: " + (e.message || e));
|
|
105
|
-
if (e.stack) console.log(e.stack);
|
|
106
|
-
}
|
|
107
|
-
}
|
|
108
|
-
});
|
|
109
|
-
}
|
|
110
|
-
const submitBtn = holder.append("button").attr("data-testid", "sjpp-summarizeCnvGeneexp-submitBtn").text("Launch Plot").style("margin", "0px 15px 15px 15px").property("disabled", true).on("click", launch);
|
|
111
|
-
async function updateUi() {
|
|
112
|
-
if (cnvGeneSameAsExp) {
|
|
113
|
-
if (expTw) {
|
|
114
|
-
cnvTw = await fillGvTw(expTw.term.gene, dtcnv);
|
|
115
|
-
}
|
|
116
|
-
}
|
|
117
|
-
cnvTableRow.style("display", cnvGeneSameAsExp ? "none" : "");
|
|
118
|
-
expSearchPrompt.text(cnvGeneSameAsExp ? "Hit ENTER to launch plot." : "");
|
|
119
|
-
submitBtn.style("display", cnvGeneSameAsExp ? "none" : "").property("disabled", !expTw || !cnvTw);
|
|
120
|
-
}
|
|
121
|
-
updateUi();
|
|
122
|
-
async function fillGvTw(geneSymbol, dt) {
|
|
123
|
-
const name = geneSymbol;
|
|
124
|
-
const tw = {
|
|
125
|
-
term: {
|
|
126
|
-
id: name,
|
|
127
|
-
name,
|
|
128
|
-
genes: [
|
|
129
|
-
{
|
|
130
|
-
kind: "gene",
|
|
131
|
-
id: name,
|
|
132
|
-
gene: name,
|
|
133
|
-
name,
|
|
134
|
-
type: "geneVariant"
|
|
135
|
-
}
|
|
136
|
-
],
|
|
137
|
-
type: "geneVariant"
|
|
138
|
-
},
|
|
139
|
-
q: { type: "predefined-groupset", dtLst: [dt] }
|
|
140
|
-
};
|
|
141
|
-
await fillTermWrapper(tw, chartsInstance.app.vocabApi);
|
|
142
|
-
return tw;
|
|
143
|
-
}
|
|
144
|
-
function launch() {
|
|
145
|
-
if (!expTw || !cnvTw) throw "either tw is missing";
|
|
146
|
-
launchPlot({
|
|
147
|
-
tw1: expTw,
|
|
148
|
-
tw2: cnvTw,
|
|
149
|
-
chartsInstance,
|
|
150
|
-
holder
|
|
151
|
-
});
|
|
152
|
-
}
|
|
153
|
-
}
|
|
154
|
-
export {
|
|
155
|
-
makeChartBtnMenu
|
|
156
|
-
};
|
|
157
|
-
//# sourceMappingURL=summarizeCnvGeneexp-76UJXLA4.js.map
|