@sjcrh/proteinpaint-client 2.203.0 → 2.203.1

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (884) hide show
  1. package/dist/2dmaf-6CEBP4SA.js +1366 -0
  2. package/dist/AIProjectAdmin-2CKKFC3A.js +951 -0
  3. package/dist/AggregateMatrix-5TBUMFE5.js +665 -0
  4. package/dist/AppHeader-5YBPWF44.js +829 -0
  5. package/dist/BoxPlot-UOJS5SJV.js +1210 -0
  6. package/dist/CorrelationVolcano-KX6JPZMT.js +613 -0
  7. package/dist/Cuminc-TLOOLZWR.js +1208 -0
  8. package/dist/DE-HUQLQ2Z3.js +87 -0
  9. package/dist/DEinput-WWUISAF2.js +404 -0
  10. package/dist/DifferentialAnalysis-6DTAGCEY.js +237 -0
  11. package/dist/Disco-P6ZLPYLF.js +3388 -0
  12. package/dist/Disco.UI-WGTMAFK2.js +242 -0
  13. package/dist/DmrPlot-3FRU5KUK.js +636 -0
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  15. package/dist/GSEA-DEEUAAMI.js +850 -0
  16. package/dist/GeneExpInput-6QWGEAFV.js +361 -0
  17. package/dist/Geomap-6HT2B7RH.js +83 -0
  18. package/dist/HicApp-PCNOUULF.js +2244 -0
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  36. package/dist/ProteomeInput-PRS3DEMZ.js +387 -0
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  153. package/dist/cohort-U7M6Q2UX.js +69 -0
  154. package/dist/condition-EGAV2PMJ.js +326 -0
  155. package/dist/controls-PTMYWUZV.js +33 -0
  156. package/dist/controls.config-DOA6PTP2.js +33 -0
  157. package/dist/correlation-Y3EL6GB7.js +94 -0
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  159. package/dist/dataDownload-EQGUAOK2.js +328 -0
  160. package/dist/databrowser.ui-ABGOJUWQ.js +424 -0
  161. package/dist/dictionary-YOLLEDE5.js +112 -0
  162. package/dist/dnaMethylation-JZT63UHO.js +32 -0
  163. package/dist/dnaMethylation.integration.spec-EATCABJW.js +197 -0
  164. package/dist/dofetch-YNBIUFV5.js +48 -0
  165. package/dist/e2pca-RD6COCRL.js +343 -0
  166. package/dist/ep-BAI7WUET.js +1248 -0
  167. package/dist/expclust.gdc.spec-LKV2CQA5.js +301 -0
  168. package/dist/facet-X3SXQIAC.js +518 -0
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  170. package/dist/geneExpClustering-BJD5U3KG.js +243 -0
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  180. package/dist/genefusion.ui-4T5R7DT7.js +302 -0
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  183. package/dist/grin2-EXBG7TMS.js +1136 -0
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  240. package/dist/proteinView-7GWHQYXC.js +1561 -0
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  818. /package/dist/{polar2-JKV74QV5.js.map → polar2-AB6SVYRS.js.map} +0 -0
  819. /package/dist/{profileForms-VDYCFH4M.js.map → profileForms-AIEHZ4GC.js.map} +0 -0
  820. /package/dist/{plot.app-MOIVGIS6.js.map → profilePlot-PZDFGXKZ.js.map} +0 -0
  821. /package/dist/{proteinView-A3EM6OR5.js.map → proteinView-7GWHQYXC.js.map} +0 -0
  822. /package/dist/{pseudbulk.unit.spec-CUMTLAH7.js.map → pseudbulk.unit.spec-NFT4VNTI.js.map} +0 -0
  823. /package/dist/{profilePlot-PR3LVRYU.js.map → pseudobulk-WDGWTXW4.js.map} +0 -0
  824. /package/dist/{pseudobulk-5E5MSMU3.js.map → qualitative-PZYJENE7.js.map} +0 -0
  825. /package/dist/{radar2-A5OYMORS.js.map → radar2-QHRGH3YS.js.map} +0 -0
  826. /package/dist/{radarFacility2-4TPJB6M4.js.map → radarFacility2-2JD26FL6.js.map} +0 -0
  827. /package/dist/{qualitative-WPXUBISK.js.map → render-YA4Z56LT.js.map} +0 -0
  828. /package/dist/{report-NCJOTYIC.js.map → report-2NUKFJTF.js.map} +0 -0
  829. /package/dist/{render-XQBWWS33.js.map → sampleView-2XVPJTVR.js.map} +0 -0
  830. /package/dist/{samplelst-FV7BAUN5.js.map → samplelst-DMILFDT5.js.map} +0 -0
  831. /package/dist/{samplematrix-DFD3PNI4.js.map → samplematrix-LYA5XTUM.js.map} +0 -0
  832. /package/dist/{sc-GIMTDVLG.js.map → sc-CM2C34MN.js.map} +0 -0
  833. /package/dist/{scatter-4GJ5HKUY.js.map → scatter-C3CH3HTF.js.map} +0 -0
  834. /package/dist/{scatter-P3ISZB3R.js.map → scatter-GO6LV6NY.js.map} +0 -0
  835. /package/dist/{selectGenomeWithTklst-ZZ4CEHDU.js.map → selectGenomeWithTklst-5C7UBTGZ.js.map} +0 -0
  836. /package/dist/{sampleView-2PUSMG4W.js.map → singleCellCellType-EZYESBVZ.js.map} +0 -0
  837. /package/dist/{singleCellCellType.unit.spec-JNEIICK5.js.map → singleCellCellType.unit.spec-DB6FM4XR.js.map} +0 -0
  838. /package/dist/{singleCellCellType-CEERCVTR.js.map → singleCellGeneExpression-DZLEFPW4.js.map} +0 -0
  839. /package/dist/{singleCellGeneExpression.unit.spec-CGRZGY66.js.map → singleCellGeneExpression.unit.spec-ZTBK3V43.js.map} +0 -0
  840. /package/dist/{singleCellGeneExpression-G5B7DDES.js.map → singleCellPlot-VF4TZ4FT.js.map} +0 -0
  841. /package/dist/{singlecell-IPTSIKNA.js.map → singlecell-2MHROPBN.js.map} +0 -0
  842. /package/dist/{singlecell-VB4KLPJF.js.map → singlecell-GPAFNOUZ.js.map} +0 -0
  843. /package/dist/{singleCellPlot-US5KTHS4.js.map → snp-K4EAEVW4.js.map} +0 -0
  844. /package/dist/{snp.unit.spec-Q537NGVG.js.map → snp.unit.spec-BUVQLVOY.js.map} +0 -0
  845. /package/dist/{snplocus-BV6WJTVP.js.map → snplocus-GEVISN6Z.js.map} +0 -0
  846. /package/dist/{spliceevent.a53ss.diagram-3BUQVK4Q.js.map → spliceevent.a53ss.diagram-5UPWNAZF.js.map} +0 -0
  847. /package/dist/{spliceevent.exonskip.diagram-CQZ2DFQ5.js.map → spliceevent.exonskip.diagram-7TKAQURC.js.map} +0 -0
  848. /package/dist/{spliceevent.noeventdiagram-QAEPR6LD.js.map → spliceevent.noeventdiagram-CDXZLR3Z.js.map} +0 -0
  849. /package/dist/{snp-6V2SCCRN.js.map → ssGSEA-NMCJUQXT.js.map} +0 -0
  850. /package/dist/{ssGSEA.unit.spec-A337IMC7.js.map → ssGSEA.unit.spec-3FQALTPQ.js.map} +0 -0
  851. /package/dist/{stattable-J4ZQKJFM.js.map → stattable-2RXQPWKK.js.map} +0 -0
  852. /package/dist/{summarizeCnvGeneexp-76UJXLA4.js.map → summarizeCnvGeneexp-4BQS5AFM.js.map} +0 -0
  853. /package/dist/{summarizeGeneexpSurvival-ZUEHXA2R.js.map → summarizeGeneexpSurvival-HTBZQFB5.js.map} +0 -0
  854. /package/dist/{summarizeMutationCnv-EBCBVMG6.js.map → summarizeMutationCnv-XUWZGPCM.js.map} +0 -0
  855. /package/dist/{ssGSEA-XNI5S7AC.js.map → summarizeMutationDiagnosis-QUJX42TO.js.map} +0 -0
  856. /package/dist/{summarizeMutationSurvival-QRFMJLLO.js.map → summarizeMutationSurvival-3R47TTR6.js.map} +0 -0
  857. /package/dist/{summarizeMutationDiagnosis-VLFI2ZIZ.js.map → summary-6UUB63QR.js.map} +0 -0
  858. /package/dist/{summary.integration.spec-52WP6SNY.js.map → summary.integration.spec-JJDE6SRV.js.map} +0 -0
  859. /package/dist/{summaryInput-WUJNHCGH.js.map → summaryInput-JG4AW6FW.js.map} +0 -0
  860. /package/dist/{sunburst-IJ3ZG2BC.js.map → sunburst-YKB42RZX.js.map} +0 -0
  861. /package/dist/{survival-SQRYWGWZ.js.map → survival-3IFFTDQA.js.map} +0 -0
  862. /package/dist/{survival-F2B5JKOO.js.map → survival-HOFNJENX.js.map} +0 -0
  863. /package/dist/{svgraph-HVCMF6KI.js.map → svgraph-WFEY4ZIZ.js.map} +0 -0
  864. /package/dist/{svmr-PROHTMTP.js.map → svmr-44EIX7YD.js.map} +0 -0
  865. /package/dist/{table-3E64OJNV.js.map → table-6MKVJUNC.js.map} +0 -0
  866. /package/dist/{termCollection-WKT6ESMI.js.map → termCollection-6JBVQL6Y.js.map} +0 -0
  867. /package/dist/{summary-U3YKEMZC.js.map → termCollection-TTELZVC5.js.map} +0 -0
  868. /package/dist/{termCollection.unit.spec-XMOCMVER.js.map → termCollection.unit.spec-6Z7X646L.js.map} +0 -0
  869. /package/dist/{termCollection-MUH7P6B5.js.map → termCollectionFractionSelection-5DVIJBM5.js.map} +0 -0
  870. /package/dist/{termCollectionFractionSelection.unit.spec-MG7E3EIZ.js.map → termCollectionFractionSelection.unit.spec-3HIM5BIF.js.map} +0 -0
  871. /package/dist/{termCollectionFractionSelection-P5G6WIJJ.js.map → tk-HSYWJCGQ.js.map} +0 -0
  872. /package/dist/{tk-HWUPUGOS.js.map → tk-PNOVG2XS.js.map} +0 -0
  873. /package/dist/{tp.ui-RRB5MJRD.js.map → tp.ui-COBBSUPB.js.map} +0 -0
  874. /package/dist/{tk-SBM2GN3S.js.map → tvs.dt-35AKURFI.js.map} +0 -0
  875. /package/dist/{tvs.dtcnv.categorical-7RJPQKMX.js.map → tvs.dtcnv.categorical-3EHXYROL.js.map} +0 -0
  876. /package/dist/{tvs.dtcnv.continuous-FW4ZXIYY.js.map → tvs.dtcnv.continuous-AXQ2GU6S.js.map} +0 -0
  877. /package/dist/{tvs.dtfusion-3GDWW3ML.js.map → tvs.dtfusion-PLJIMPNX.js.map} +0 -0
  878. /package/dist/{tvs.dtitd-FER4H4UO.js.map → tvs.dtitd-JS6RFBV5.js.map} +0 -0
  879. /package/dist/{tvs.dtsnvindel-ISEOJ5UA.js.map → tvs.dtsnvindel-MDEM5MPT.js.map} +0 -0
  880. /package/dist/{tvs.dtsv-JDML7EWE.js.map → tvs.dtsv-OU756YLO.js.map} +0 -0
  881. /package/dist/{tvs.samplelst-MJTM6GSV.js.map → tvs.samplelst-5NDICES4.js.map} +0 -0
  882. /package/dist/{tvs.termCollection-GMOXBJWF.js.map → tvs.termCollection-5URPDPH6.js.map} +0 -0
  883. /package/dist/{tvs.dt-I2ECKHQ2.js.map → vocabulary-CHCVMPK5.js.map} +0 -0
  884. /package/dist/{wsi.direct-IVPACPNT.js.map → wsi.direct-JSKV4H4X.js.map} +0 -0
@@ -1,797 +0,0 @@
1
- import {
2
- PlotBase,
3
- sayerror
4
- } from "./chunk-GQQ4R6BI.js";
5
- import {
6
- DEFAULT_SAMPLE_TYPE,
7
- ROOT_SAMPLE_TYPE,
8
- getDateStrFromNumber,
9
- isNumericTerm
10
- } from "./chunk-7UFK4GVI.js";
11
- import {
12
- copyMerge,
13
- getCompInit
14
- } from "./chunk-H6INPPUC.js";
15
- import {
16
- select_default
17
- } from "./chunk-I6Y4O3RR.js";
18
-
19
- // plots/sampleView.ts
20
- var root_ID = "root";
21
- var samplesLimit = 15;
22
- var SampleView = class _SampleView extends PlotBase {
23
- static {
24
- this.type = "sampleView";
25
- }
26
- constructor(opts, api) {
27
- super(opts, api);
28
- this.type = _SampleView.type;
29
- this.setDom(opts);
30
- setInteractivity(this);
31
- setRenderers(this);
32
- }
33
- setDom(opts) {
34
- opts.holder.style("position", "relative");
35
- const div = opts.holder.append("div");
36
- const controlsDiv = div.append("div").style("display", "inline-block");
37
- const headerDiv = div.append("div").style("display", "inline-block").style("padding", "20px");
38
- const contentDiv = div.append("div").style("display", "flex").style("flex-direction", "row").style("flex-wrap", "wrap").style("justify-content", "flex-start").style("width", "100vw");
39
- const plotsDiv = contentDiv;
40
- const sampleDiv = headerDiv.insert("div").style("display", "inline-block");
41
- const showPlotsDiv = headerDiv.append("div").style("display", "inline-block").style("vertical-align", "top");
42
- const loadingDiv = opts.holder.append("div").attr("class", "sjpp-loading-overlay").style("display", "none");
43
- loadingDiv.append("div").attr("class", "sjpp-spinner");
44
- this.dom = {
45
- header: opts.header,
46
- holder: opts.holder,
47
- controlsDiv,
48
- sampleDiv,
49
- showPlotsDiv,
50
- loadingDiv,
51
- plotsDiv
52
- };
53
- }
54
- async init(appState) {
55
- this.termsByCohort = {};
56
- await this.setSampleSelect(appState);
57
- const state = this.getState(appState);
58
- await this.setControls(state);
59
- }
60
- async setSampleSelect(appState) {
61
- const config = appState.plots.find((p) => p.id === this.id);
62
- const sampleDiv = this.dom.sampleDiv;
63
- if (this.dom.header) this.dom.header.html(`Sample View`);
64
- if (config.samples && config.samples.length > 1) {
65
- const select = sampleDiv.insert("select").style("margin", "0px 5px").property("multiple", true).attr("id", "select");
66
- select.selectAll("option").data(config.samples).enter().append("option").attr("value", (d) => d.sampleId).property("selected", (d, _i) => _i < samplesLimit).html((d, _) => d.sampleName);
67
- this.dom.noteDiv = sampleDiv.insert("div").style("display", "none").style("vertical-align", "top").style("font-size", "0.8em").style("color", "#aaa").html(
68
- `*Note that only ${samplesLimit} samples can be selected.<br/>&nbsp;Navigate through the list to view all the samples.`
69
- );
70
- if (config.samples.length > samplesLimit) this.dom.noteDiv.style("display", "inline-block");
71
- select.on("change", () => {
72
- const options = select.node().options;
73
- const samples = [];
74
- let count = 0;
75
- for (const option of options) {
76
- if (option.selected) {
77
- if (count < samplesLimit) {
78
- const sampleId = Number(option.value);
79
- const sampleName = config.samples.find((s) => s.sampleId == sampleId).sampleName;
80
- const sample = { sampleId, sampleName };
81
- samples.push(sample);
82
- count++;
83
- } else option.selected = false;
84
- }
85
- }
86
- this.app.dispatch({ type: "plot_edit", id: this.id, config: { samples } });
87
- });
88
- } else {
89
- this.samplesData = await this.vocabApi.getSamplesByName({
90
- filter: appState.termfilter?.filter
91
- });
92
- if (Object.keys(this.samplesData).length == 0) throw "No accessible samples found";
93
- const callback = (sampleName2) => {
94
- if (this.samplesData[sampleName2]) {
95
- const samples = getSamplesRelated(this.samplesData, sampleName2, null, void 0);
96
- this.app.dispatch({ type: "plot_edit", id: this.id, config: { samples } });
97
- this.dom.downloadbt.property("disabled", false);
98
- } else {
99
- this.dom.tableDiv.style("display", "none");
100
- for (const div of this.discoPlots) div.cellDiv.style("display", "none");
101
- for (const div of Object.values(this.singleSamplePlots)) {
102
- div.forEach((p) => p.cellDiv.style("display", "none"));
103
- }
104
- for (const div of this.brainPlots) div.cellDiv.style("display", "none");
105
- if (sampleName2 != "") {
106
- this.dom.downloadbt.property("disabled", true);
107
- const errorDiv = sampleDiv.append("div");
108
- sayerror(errorDiv, `Invalid sample ID: ${sampleName2}. Please check the sample ID.`);
109
- setTimeout(() => {
110
- errorDiv.remove();
111
- }, 6e3);
112
- }
113
- }
114
- };
115
- const hasSampleAncestry = appState.termdbConfig.hasSampleAncestry;
116
- const sampleName = searchSampleInput(this.dom.sampleDiv, this.samplesData, hasSampleAncestry, callback, void 0);
117
- this.sample = config.sample || { sampleId: this.samplesData[sampleName].id, sampleName };
118
- if (config.sample?.sampleName) sampleDiv.select("input").property("value", config.sample.sampleName);
119
- this.dom.downloadbt = sampleDiv.insert("button").style("margin-left", "10px").style("vertical-align", "top").text("Download").on("click", () => {
120
- this.downloadData();
121
- });
122
- this.dom.messageDiv = sampleDiv.insert("div").style("display", "inline-block").style("display", "none").style("vertical-align", "top").html("&nbsp;&nbsp;Downloading data ...");
123
- }
124
- }
125
- getState(appState) {
126
- const config = appState.plots?.find((p) => p.id === this.id);
127
- let samples = config.samples || getSamplesRelated(this.samplesData, this.sample.sampleName, null, void 0);
128
- if (config.samples?.length > 15) samples = config.samples.filter((s, i) => i < 15);
129
- const q = appState.termdbConfig.queries;
130
- const state = {
131
- config,
132
- termfilter: appState.termfilter,
133
- // TODO: use state.config drectly, instead of having to extract
134
- // selected config.key-values into the component state
135
- activeCohort: config.activeCohort,
136
- terms: config.terms,
137
- expandedTermIds: config.expandedTermIds,
138
- samples,
139
- singleSampleGenomeQuantification: q?.singleSampleGenomeQuantification,
140
- singleSampleMutation: q?.singleSampleMutation,
141
- NIdata: q?.NIdata,
142
- hasVerifiedToken: this.app.vocabApi.hasVerifiedToken(),
143
- tokenVerificationPayload: this.app.vocabApi.tokenVerificationPayload,
144
- termdbConfig: appState.termdbConfig,
145
- vocab: appState.vocab
146
- };
147
- if (appState.termdbConfig.selectCohort) {
148
- state.toSelectCohort = true;
149
- const choice = appState.termdbConfig.selectCohort.values[state.activeCohort];
150
- if (choice) {
151
- state.cohortValuelst = choice.keys;
152
- }
153
- }
154
- return state;
155
- }
156
- async main() {
157
- if (this.mayRequireToken()) return;
158
- this.dom.loadingDiv.style("display", "");
159
- try {
160
- this.config = structuredClone(this.state.config);
161
- this.settings = this.state.config.settings.sampleView;
162
- this.dom.plotsDiv.selectAll("*").remove();
163
- this.termsById = this.getTermsById(this.state);
164
- this.sampleDataByTermId = {};
165
- const root = this.termsById[root_ID];
166
- root.terms = await this.requestTermRecursive(root);
167
- this.orderedVisibleTerms = this.getOrderedVisibleTerms(root);
168
- if (this.dom.downloadbt)
169
- this.dom.downloadbt.style("display", this.settings.showDictionary ? "inline-block" : "none");
170
- if (this.settings.showDictionary) this.renderSampleDictionary();
171
- this.dom.tableDiv.style("display", this.settings.showDictionary ? "block" : "none");
172
- await this.renderPlots(this.state, this.state.samples);
173
- this.showVisiblePlots();
174
- } finally {
175
- this.dom.loadingDiv.style("display", "none");
176
- }
177
- }
178
- async setControls(state) {
179
- const q = state.termdbConfig.queries;
180
- const hasPlots = q?.singleSampleMutation || q?.singleSampleGenomeQuantification || q?.NIdata || q?.images || q?.WSImages;
181
- if (hasPlots) {
182
- this.dom.showPlotsDiv.append("input").attr("id", "showDictionary").attr("type", "checkbox").property("checked", true).on("change", (e) => {
183
- this.app.dispatch({
184
- type: "plot_edit",
185
- id: this.id,
186
- config: { settings: { sampleView: { showDictionary: e.target.checked } } }
187
- });
188
- });
189
- this.dom.showPlotsDiv.append("label").text("Show Dictionary").attr("for", "showDictionary");
190
- }
191
- if (q?.WSImages) {
192
- this.dom.showPlotsDiv.append("input").attr("id", "showWsi").attr("type", "checkbox").property("checked", true).on("change", (e) => {
193
- this.app.dispatch({
194
- type: "plot_edit",
195
- id: this.id,
196
- config: { settings: { sampleView: { showWsi: e.target.checked } } }
197
- });
198
- });
199
- this.dom.showPlotsDiv.append("label").attr("for", "showWsi").text("Show WSI images");
200
- }
201
- if (q?.singleSampleMutation) {
202
- this.dom.showPlotsDiv.append("input").attr("type", "checkbox").property("checked", true).attr("id", "showDisco").on("change", (e) => {
203
- this.app.dispatch({
204
- type: "plot_edit",
205
- id: this.id,
206
- config: { settings: { sampleView: { showDisco: e.target.checked } } }
207
- });
208
- });
209
- this.dom.showPlotsDiv.append("label").text("Show Disco").attr("for", "showDisco");
210
- }
211
- if (q?.singleSampleGenomeQuantification) {
212
- for (const ssgqKey in q.singleSampleGenomeQuantification) {
213
- const label = ssgqKey.replace(/([a-z](?=[A-Z]))/g, "$1 ");
214
- this.dom.showPlotsDiv.append("input").attr("type", "checkbox").property("checked", true).attr("id", ssgqKey).on("change", (e) => {
215
- this.app.dispatch({
216
- type: "plot_edit",
217
- id: this.id,
218
- config: { settings: { sampleView: { [ssgqKey]: e.target.checked } } }
219
- });
220
- });
221
- this.dom.showPlotsDiv.append("label").text("Show " + label).attr("for", ssgqKey);
222
- }
223
- }
224
- if (q?.images) {
225
- this.dom.showPlotsDiv.append("input").attr("type", "checkbox").property("checked", true).attr("id", "showImages").on("change", (e) => {
226
- this.app.dispatch({
227
- type: "plot_edit",
228
- id: this.id,
229
- config: { settings: { sampleView: { showImages: e.target.checked } } }
230
- });
231
- });
232
- this.dom.showPlotsDiv.append("label").text("Show Images").attr("for", "showImages");
233
- }
234
- if (q?.NIdata) {
235
- this.dom.showPlotsDiv.append("input").attr("type", "checkbox").property("checked", true).attr("id", "showBrainImaging").on("change", (e) => {
236
- this.app.dispatch({
237
- type: "plot_edit",
238
- id: this.id,
239
- config: { settings: { sampleView: { showBrainImaging: e.target.checked } } }
240
- });
241
- });
242
- this.dom.showPlotsDiv.append("label").text("Show brain imaging").attr("for", "showBrainImaging");
243
- }
244
- }
245
- getTermsById(state) {
246
- if (!(state.activeCohort in this.termsByCohort)) {
247
- this.termsByCohort[state.activeCohort] = {
248
- [root_ID]: {
249
- id: root_ID,
250
- __tree_isroot: true
251
- // must not delete this flag
252
- }
253
- };
254
- }
255
- return this.termsByCohort[state.activeCohort];
256
- }
257
- async requestTermRecursive(term, _ancestry = [root_ID]) {
258
- const data = await this.vocabApi.getTermChildren(
259
- term,
260
- this.state.toSelectCohort ? this.state.cohortValuelst : null,
261
- this.state.termfilter.filter
262
- );
263
- if (data.error) throw data.error;
264
- if (!data.lst || data.lst.length == 0) {
265
- return [];
266
- }
267
- const terms = [];
268
- const parent_id = _ancestry.slice(-1)[0];
269
- for (const t of data.lst) {
270
- t.parent_id = parent_id;
271
- const ancestry = [..._ancestry];
272
- const copy = structuredClone(t);
273
- copy.ancestry = ancestry;
274
- terms.push(copy);
275
- if (!copy.isleaf && this.config.expandedTermIds.includes(copy.id)) {
276
- copy.terms = await this.requestTermRecursive(copy, [...ancestry, t.id]);
277
- if (this.state.samples) await this.fillSampleData(copy.terms);
278
- } else {
279
- const t0 = this.termsById[copy.id];
280
- if (this.state.samples) await this.fillSampleData([copy]);
281
- if (t0 && t0.terms) {
282
- copy.terms = t0.terms;
283
- }
284
- }
285
- this.termsById[copy.id] = copy;
286
- }
287
- return terms;
288
- }
289
- getOrderedVisibleTerms(_root) {
290
- const visibleTerms = Object.values(this.termsById).filter(this.isVisibleTermId.bind(this));
291
- const orderedVisibleTerms = [];
292
- this.sortVisibleTerms(this.termsById[root_ID], visibleTerms, orderedVisibleTerms);
293
- return orderedVisibleTerms;
294
- }
295
- isVisibleTermId(term) {
296
- if (term.parent_id == root_ID) return true;
297
- if (!term.ancestry) return false;
298
- for (const pid of term.ancestry) {
299
- if (pid === root_ID) continue;
300
- if (!this.config.expandedTermIds.includes(pid)) return false;
301
- }
302
- return true;
303
- }
304
- sortVisibleTerms(currParent, remainingTerms, currOrder = []) {
305
- const unorderedTerms = [];
306
- const orderedTerms = [];
307
- for (const term of remainingTerms) {
308
- if (term.parent_id == currParent.id) {
309
- orderedTerms.push(term);
310
- } else unorderedTerms.push(term);
311
- }
312
- remainingTerms.splice(0, remainingTerms.length, ...unorderedTerms);
313
- if (remainingTerms.length) {
314
- for (const term of orderedTerms) {
315
- currOrder.push(term);
316
- if (!term.isleaf && remainingTerms.length) {
317
- this.sortVisibleTerms(term, remainingTerms, currOrder);
318
- }
319
- }
320
- } else {
321
- currOrder.push(...orderedTerms);
322
- }
323
- }
324
- async fillSampleData(terms) {
325
- const term_ids = [];
326
- for (const term of terms) term_ids.push(term.id);
327
- for (const sample of this.state.samples) {
328
- const data = await this.vocabApi.getSingleSampleData({
329
- sampleId: sample.sampleId,
330
- term_ids,
331
- filter: this.state.termfilter.filter
332
- });
333
- if ("error" in data) throw data.error;
334
- if (!this.sampleDataByTermId[sample.sampleId]) this.sampleDataByTermId[sample.sampleId] = {};
335
- for (const id in data) this.sampleDataByTermId[sample.sampleId][id] = data[id];
336
- }
337
- }
338
- async downloadData() {
339
- this.dom.messageDiv.style("display", "block");
340
- this.dom.downloadbt.style("display", "none");
341
- const filename = `samples.tsv`;
342
- const sampleData = {};
343
- let lines = "Sample";
344
- for (const sample of this.state.samples) {
345
- sampleData[sample.sampleId] = await this.vocabApi.getSingleSampleData({
346
- sampleId: sample.sampleId,
347
- /** term_ids is required for getSingleSampleData but not
348
- * available in this instance. Pass empty array.*/
349
- term_ids: [],
350
- filter: this.state.termfilter.filter || []
351
- });
352
- lines += ` ${sample.sampleName}`;
353
- }
354
- lines += "\n";
355
- const sampleId = this.state.samples[0].sampleId;
356
- for (const termId in sampleData[sampleId]) {
357
- const term = sampleData[sampleId][termId].term;
358
- lines += `${term.name}`;
359
- for (const sampleId2 in sampleData) {
360
- const data = sampleData[sampleId2];
361
- let value = getTermValue(term, data);
362
- if (value == null) value = "Missing";
363
- lines += ` ${value}`;
364
- }
365
- lines += "\n";
366
- }
367
- const dataStr = "data:text/tsv;charset=utf-8," + encodeURIComponent(lines);
368
- const link = document.createElement("a");
369
- link.setAttribute("href", dataStr);
370
- link.setAttribute("download", filename);
371
- document.body.appendChild(link);
372
- link.click();
373
- link.remove();
374
- this.dom.messageDiv.style("display", "none");
375
- this.dom.downloadbt.style("display", "inline-block");
376
- }
377
- mayRequireToken() {
378
- if (this.state.hasVerifiedToken) {
379
- this.dom.holder.style("display", "block");
380
- return false;
381
- } else {
382
- const e = this.state.tokenVerificationPayload;
383
- const missingAccess = e?.error == "Missing access" && this.state.termdbConfig.dataDownloadCatch?.missingAccess;
384
- const message = missingAccess?.message?.replace("MISSING-ACCESS-LINK", missingAccess?.links[e?.linkKey]);
385
- const helpLink = this.state.termdbConfig.dataDownloadCatch?.helpLink;
386
- this.dom.holder.style("color", "#e44").style("padding", "10px").html(
387
- message || (this.state.tokenVerificationMessage || "Requires sign-in") + (helpLink ? ` <a href='${helpLink}' target=_blank>Tutorial</a>` : "")
388
- );
389
- return true;
390
- }
391
- }
392
- showVisiblePlots() {
393
- this.visiblePlots = false;
394
- this.showPlotsFromCategory(this.discoPlots, "showDisco");
395
- for (const ssgqKey in this.state.singleSampleGenomeQuantification)
396
- this.showPlotsFromCategory(this.singleSamplePlots[ssgqKey], ssgqKey);
397
- this.showPlotsFromCategory(this.brainPlots, "showBrain");
398
- this.showPlotsFromCategory(this.imagePlots, "showImages");
399
- this.showPlotsFromCategory(this.wsiPlots, "showWsi");
400
- if (this.state.samples.length == 1 && this.visiblePlots)
401
- this.dom.tableDiv.style("max-width", "48vw").style("max-height", "40vw").attr("class", "sjpp_show_scrollbar");
402
- else this.dom.tableDiv.style("max-width", "").style("max-height", "").attr("class", "");
403
- }
404
- showPlotsFromCategory(plots, key) {
405
- for (const div of plots) {
406
- const visibleSample = this.state.samples.find((s) => s.sampleName == div.sample.sampleName);
407
- const visiblePlot = this.settings[key] && visibleSample;
408
- if (visiblePlot) this.visiblePlots = true;
409
- div.cellDiv.style("display", visiblePlot ? "table-cell" : "none");
410
- }
411
- }
412
- async renderPlots(state, samples) {
413
- const plotsDiv = this.dom.plotsDiv;
414
- this.discoPlots = [];
415
- this.singleSamplePlots = {};
416
- this.brainPlots = [];
417
- this.imagePlots = [];
418
- this.wsiPlots = [];
419
- if (state.termdbConfig.queries?.WSImages) {
420
- const div = plotsDiv.append("div");
421
- if (state.samples.length == 1) div.style("display", "inline-block").style("width", "50vw");
422
- for (const sample of samples) {
423
- const cellDiv = div.append("div").style("display", "inline-block");
424
- this.wsiPlots.push({ sample, cellDiv });
425
- const wsiViewer = await import("./plot.wsi-DAC7NUQE.js");
426
- wsiViewer.default(state.vocab.dslabel, cellDiv, this.app.opts.genome, sample.sampleName);
427
- }
428
- }
429
- if (state.termdbConfig?.queries?.singleSampleMutation) {
430
- const div = plotsDiv.append("div");
431
- if (state.samples.length == 1) div.style("display", "inline-block").style("width", "50vw");
432
- let someFound = false;
433
- for (const sample of samples) {
434
- const cellDiv = div.append("div").style("display", "inline-block");
435
- this.discoPlots.push({ sample, cellDiv });
436
- const header = cellDiv.insert("div");
437
- const discoPlotImport = await import("./plot.disco-4R5J7Z5S.js");
438
- const found = await discoPlotImport.default(
439
- state.termdbConfig,
440
- state.vocab.dslabel,
441
- { sample_id: sample.sampleName },
442
- cellDiv,
443
- this.app.opts.genome,
444
- {},
445
- //overrides
446
- false
447
- //showError
448
- );
449
- if (found) {
450
- if (state.samples.length > 1)
451
- header.style("font-weight", "bold").style("padding-left", "20px").text(sample.sampleName);
452
- someFound = true;
453
- }
454
- }
455
- this.dom.showPlotsDiv.select("input[id=showDisco").style("display", someFound ? "inline-block" : "none");
456
- this.dom.showPlotsDiv.select("label[for=showDisco").style("display", someFound ? "inline-block" : "none");
457
- }
458
- if (state.termdbConfig.queries?.singleSampleGenomeQuantification) {
459
- for (const k in state.termdbConfig.queries.singleSampleGenomeQuantification) {
460
- let someFound = false;
461
- this.singleSamplePlots[k] = [];
462
- const div = plotsDiv.append("div");
463
- if (state.samples.length == 1) div.style("display", "inline-block").style("width", "50vw");
464
- for (const sample of samples) {
465
- const label = (k.match(/[A-Z][a-z]+|[0-9]+/g) || []).join(" ");
466
- const plotDiv = div.insert("div").style("display", "table-cell").style("padding", "20px");
467
- this.singleSamplePlots[k].push({ sample, cellDiv: plotDiv });
468
- if (state.samples.length > 1)
469
- plotDiv.insert("div").style("font-weight", "bold").text(`${sample.sampleName} ${label}`);
470
- const ssgqImport = await import("./plot.ssgq-6LCKYRYD.js");
471
- const found = await ssgqImport.plotSingleSampleGenomeQuantification(
472
- state.termdbConfig,
473
- state.vocab.dslabel,
474
- k,
475
- { sample_id: sample.sampleName },
476
- plotDiv.insert("div"),
477
- this.app.opts.genome,
478
- null,
479
- //geneName
480
- false
481
- //showError
482
- );
483
- if (found) someFound = true;
484
- }
485
- this.dom.showPlotsDiv.select(`input[id=${k}`).style("display", someFound ? "inline-block" : "none");
486
- this.dom.showPlotsDiv.select(`label[for=${k}`).style("display", someFound ? "inline-block" : "none");
487
- }
488
- }
489
- if (state.termdbConfig.queries?.NIdata) {
490
- for (const k in state.termdbConfig.queries?.NIdata) {
491
- const div = plotsDiv.append("div");
492
- if (state.samples.length == 1) div.style("display", "inline-block").style("width", "50vw");
493
- for (const sample of samples) {
494
- const plotDiv = div.insert("div").style("display", "inline-block");
495
- this.brainPlots.push({ sample, cellDiv: plotDiv });
496
- if (state.samples.length > 1)
497
- plotDiv.insert("div").style("font-weight", "bold").style("padding-left", "20px").text(sample.sampleName);
498
- const brainImagingImport = await import("./plot.brainImaging-Y32KQFLS.js");
499
- brainImagingImport.default(
500
- state.termdbConfig,
501
- state.vocab.dslabel,
502
- k,
503
- { sample_id: sample.sampleName },
504
- plotDiv,
505
- this.app.opts.genome
506
- );
507
- }
508
- }
509
- }
510
- if (state.termdbConfig?.queries?.images) {
511
- const div = plotsDiv.append("div");
512
- if (state.samples.length == 1) div.style("display", "inline-block").style("width", "50vw");
513
- for (const sample of samples) {
514
- const cellDiv = div.append("div").style("display", "inline-block");
515
- this.imagePlots.push({ sample, cellDiv });
516
- if (state.samples.length > 1)
517
- cellDiv.insert("div").style("font-weight", "bold").style("padding-left", "20px").text(sample.sampleName);
518
- const imagePlotImport = await import("./imagePlot-IPTIFVLT.js");
519
- imagePlotImport.renderImagePlot(state, cellDiv, sample);
520
- }
521
- }
522
- }
523
- };
524
- function getTermValue(term, data) {
525
- let value = data[term.id]?.value;
526
- if (value == null || value == void 0 || value == "undefined") return null;
527
- if (term.type == "date") return getDateStrFromNumber(value);
528
- if (isNumericTerm(term)) {
529
- value = term.values?.[value]?.label || term.values?.[value]?.key || value;
530
- if (isNaN(value)) return value;
531
- return value % 1 == 0 ? value.toString() : value.toFixed(2).toString();
532
- }
533
- if (term.type == "categorical") return term.values[value]?.label || term.values[value]?.key;
534
- if (term.type == "condition") {
535
- const values = value.toString().split(" ");
536
- const [years, statusKey] = values;
537
- const status = term.values[statusKey].label || term.values[statusKey].key;
538
- return `Max grade: ${status}, Time to event: ${Number(years).toFixed(1)} years`;
539
- }
540
- if (term.type == "survival") {
541
- const values = value.split(" ");
542
- const [years, statusKey] = values;
543
- const status = term.values?.[statusKey]?.label || term.values?.[statusKey]?.key || statusKey;
544
- return `${status} after ${Number(years).toFixed(1)} years`;
545
- }
546
- return null;
547
- }
548
- var sampleViewInit = getCompInit(SampleView);
549
- var componentInit = sampleViewInit;
550
- function setRenderers(self) {
551
- self.renderSampleDictionary = function() {
552
- this.dom.tableDiv = this.dom.plotsDiv.append("div").style("display", "inline-block").style("padding", "20px");
553
- const table = this.dom.tableDiv.append("table").style("border-collapse", "collapse");
554
- const thead = table.append("thead");
555
- const theadrow = thead.append("tr");
556
- const tbody = table.append("tbody");
557
- const visibleSamples = [];
558
- for (const sample of self.state.samples) visibleSamples.push(self.sampleDataByTermId[sample.sampleId]);
559
- self.renderTHead(["", ...self.state.samples.map((s) => s.sampleName)], theadrow);
560
- const tBodyData = self.orderedVisibleTerms.map((term, _trIndex) => [
561
- { term },
562
- // first column, no sample data
563
- // create data to bind for each sample column
564
- ...visibleSamples.map((sample) => ({ term, sample }))
565
- ]);
566
- self.renderTBody(tBodyData, tbody);
567
- };
568
- self.renderTHead = function(data, theadrow) {
569
- const trs = theadrow.selectAll("th").data(data);
570
- trs.exit().remove();
571
- trs.html(self.getThHtml);
572
- trs.enter().append("th").style("padding", "5px 10px").style("text-align", "end").html(self.getThHtml);
573
- };
574
- self.getThHtml = (d) => d;
575
- self.renderTBody = function(data, tbody) {
576
- const trs = tbody.selectAll("tr").data(data);
577
- trs.exit().remove();
578
- trs.each(self.renderTr);
579
- trs.enter().append("tr").each(self.renderTr);
580
- };
581
- self.renderTr = function(trData, _trIndex) {
582
- const tds = select_default(this).selectAll("td").data(trData, (d) => d);
583
- tds.exit().remove();
584
- tds.each(self.renderTd);
585
- tds.enter().append("td").style("border-bottom", "solid 1px rgb(245,245,245)").style("text-align", (d, _i) => _i === 0 ? "left" : "center").style("padding", "2px 10px").each(self.renderTd);
586
- };
587
- self.renderTd = function(d, _i) {
588
- if (!d.sample) {
589
- self.renderTerm(select_default(this));
590
- return;
591
- }
592
- const term = d.term;
593
- const isNumeric = isNumericTerm(term);
594
- const value = getTermValue(d.term, d.sample);
595
- const td = select_default(this).datum(d).style("text-align", "end").style("padding", "5px 10px").html(d.sample[d.term.id]?.label || value);
596
- if (isNumeric)
597
- td.append("button").style("margin-left", "5px").text("Plot").on("click", () => {
598
- const tw = { id: term.id, q: { mode: "continuous" } };
599
- self.app.dispatch({ type: "plot_create", config: { chartType: "violin", term: tw, value } });
600
- });
601
- };
602
- self.renderTerm = function(td) {
603
- const d = td.datum();
604
- if (!td.select("span").size()) {
605
- const span2 = td.append("span");
606
- span2.append("button").style("border-width", 0).style("border-radius", "5px").style("width", "28px").style("height", "28px").style("cursor", "pointer");
607
- span2.append("span").style("margin-left", `3px`).style("cursor", "pointer");
608
- td.on("click", self.toggleTerm);
609
- }
610
- const leftIndent = (d.term.ancestry.length - 1) * 24;
611
- const span = td.select(":scope>span").style("margin-left", `${leftIndent}px`);
612
- span.select("button").style("display", d.term.isleaf ? "none" : "").html(self.config.expandedTermIds.includes(d.term.id) ? "-" : "+");
613
- span.select("span").html(d.term.name);
614
- return;
615
- };
616
- }
617
- function setInteractivity(self) {
618
- self.toggleTerm = function() {
619
- const d = select_default(this).datum();
620
- if (d.term.isleaf) return;
621
- const expandedTermIds = self.config.expandedTermIds.slice();
622
- const i = expandedTermIds.indexOf(d.term.id);
623
- if (i == -1) expandedTermIds.push(d.term.id);
624
- else expandedTermIds.splice(i, 1);
625
- self.app.dispatch({
626
- type: "plot_edit",
627
- id: self.id,
628
- config: { expandedTermIds }
629
- });
630
- };
631
- }
632
- async function getPlotConfig(opts, app) {
633
- const q = app.getState()?.termdbConfig?.queries;
634
- const settings = {
635
- sampleView: {
636
- showDictionary: true,
637
- showDisco: true,
638
- showBrain: true,
639
- showImages: true,
640
- showWsi: true
641
- }
642
- };
643
- if (q)
644
- for (const ssgqKey in q.singleSampleGenomeQuantification) settings.sampleView[ssgqKey] = true;
645
- const config = { activeCohort: 0, sample: null, expandedTermIds: [root_ID], settings, hidePlotFilter: true };
646
- return copyMerge(config, opts);
647
- }
648
- function searchSampleInput(holder, samplesData, hasSampleAncestry, callback, keyUpCallback) {
649
- const limit = 100;
650
- const allSamples = [];
651
- for (const sample in samplesData) {
652
- const sample_type = samplesData[sample].sample_type;
653
- if (sample_type == ROOT_SAMPLE_TYPE || sample_type == null || !hasSampleAncestry && sample_type == DEFAULT_SAMPLE_TYPE)
654
- allSamples.push(sample);
655
- }
656
- const isBigDataset = allSamples.length > 1e4;
657
- if (allSamples.length == 0)
658
- return;
659
- const { childrenByParent, rootFor } = buildHierarchy(samplesData);
660
- const sampleName = allSamples[0];
661
- const input = holder.append("input").attr("list", "sampleDatalist").property("autocomplete", "off").attr("placeholder", sampleName).style("width", "250px");
662
- holder.style("opacity", "0.8");
663
- const datalist = holder.append("datalist").attr("id", "sampleDatalist");
664
- addOptions(allSamples);
665
- input.on("keyup", () => {
666
- datalist.selectAll("*").remove();
667
- const str = input.node().value.toLowerCase();
668
- if (keyUpCallback) keyUpCallback(str);
669
- const options = [];
670
- for (const sample of allSamples) {
671
- if (sample.toLowerCase().startsWith(str)) options.push(sample);
672
- if (options.length == limit && allSamples.length > 1e4) break;
673
- }
674
- for (const sample of allSamples) {
675
- if (sample.toLowerCase().includes(str) && !options.includes(sample)) options.push(sample);
676
- if (options.length == limit && allSamples.length > 1e4) break;
677
- }
678
- if (options.length > 1 || options.length == 1 && input.node().value != options[0]) addOptions(options);
679
- });
680
- input.on("change", () => {
681
- const sampleName2 = input.node().value;
682
- callback(sampleName2);
683
- });
684
- function addOptions(options) {
685
- datalist.selectAll("option").data(options.filter((s, i) => i < limit)).enter().append("option").attr("value", (d) => d).attr(
686
- "label",
687
- (d, i) => getLabel(d, childrenByParent, rootFor) + (i + 1 == limit ? isBigDataset ? ` Showing first ${i + 1} hits` : ` Showing ${i + 1} of ${options.length} hits` : i + 1 === options.length && i > 0 ? ` (Found ${options.length} hits)` : "")
688
- );
689
- }
690
- function getLabel(sampleName2, childrenByParent2, rootFor2) {
691
- const rootName = rootFor2.get(sampleName2) || sampleName2;
692
- if (!childrenByParent2.has(rootName)) return sampleName2;
693
- const rootChildren = childrenByParent2.get(rootName) || [];
694
- if (rootChildren.length === 0) return sampleName2;
695
- const parts = [];
696
- for (const child of rootChildren) {
697
- const chain = [child];
698
- let cur = child;
699
- let kids = childrenByParent2.get(cur) || [];
700
- while (kids.length > 0) {
701
- chain.push(kids[0]);
702
- cur = kids[0];
703
- kids = childrenByParent2.get(cur) || [];
704
- }
705
- parts.push(chain.length > 1 ? chain.join(" > ") : child);
706
- }
707
- return parts.join(", ");
708
- }
709
- return sampleName;
710
- }
711
- function buildHierarchy(samplesData) {
712
- const childrenByParent = /* @__PURE__ */ new Map();
713
- const rootFor = /* @__PURE__ */ new Map();
714
- for (const s of Object.values(samplesData)) {
715
- const childName = s.name;
716
- const parentName = s.ancestor_name;
717
- if (parentName) {
718
- if (!childrenByParent.has(parentName)) {
719
- childrenByParent.set(parentName, []);
720
- }
721
- childrenByParent.get(parentName).push(childName);
722
- }
723
- let root = childName;
724
- let curr = s;
725
- while (curr?.ancestor_name) {
726
- root = curr.ancestor_name;
727
- curr = samplesData[root];
728
- }
729
- rootFor.set(childName, root);
730
- }
731
- for (const list of childrenByParent.values()) {
732
- list.sort((a, b) => {
733
- const na = Number(a);
734
- const nb = Number(b);
735
- return !isNaN(na) && !isNaN(nb) ? na - nb : a.localeCompare(b);
736
- });
737
- }
738
- return { childrenByParent, rootFor };
739
- }
740
- function getSamplesRelated(samplesData, sampleName, childrenByParent = null, rootFor) {
741
- if (!samplesData[sampleName]) return [];
742
- let rootName;
743
- if (rootFor && childrenByParent) {
744
- rootName = rootFor.get(sampleName);
745
- } else {
746
- rootName = sampleName;
747
- let current = samplesData[sampleName];
748
- while (current?.ancestor_name) {
749
- rootName = current.ancestor_name;
750
- current = samplesData[rootName];
751
- }
752
- }
753
- const root = samplesData[rootName];
754
- if (!root) return [];
755
- let kidsMap = childrenByParent;
756
- if (!kidsMap) {
757
- kidsMap = /* @__PURE__ */ new Map();
758
- for (const s of Object.values(samplesData)) {
759
- if (s.ancestor_name) {
760
- if (!kidsMap.has(s.ancestor_name)) kidsMap.set(s.ancestor_name, []);
761
- kidsMap.get(s.ancestor_name).push(s);
762
- }
763
- }
764
- for (const list of kidsMap.values()) {
765
- list.sort((a, b) => {
766
- const na = Number(a.name);
767
- const nb = Number(b.name);
768
- if (!isNaN(na) && !isNaN(nb)) return na - nb;
769
- return a.name.localeCompare(b.name);
770
- });
771
- }
772
- }
773
- const samples = [];
774
- const hasChildren = (kidsMap.get(rootName) || []).length > 0;
775
- if (root.sample_type !== ROOT_SAMPLE_TYPE || !hasChildren) {
776
- samples.push({ sampleId: root.id, sampleName: root.name });
777
- }
778
- function traverse(parentName) {
779
- const kids = kidsMap.get(parentName) || [];
780
- for (const kid of kids) {
781
- samples.push({ sampleId: kid.id, sampleName: kid.name });
782
- traverse(kid.name);
783
- }
784
- }
785
- traverse(rootName);
786
- return samples;
787
- }
788
-
789
- export {
790
- getTermValue,
791
- sampleViewInit,
792
- componentInit,
793
- getPlotConfig,
794
- searchSampleInput,
795
- getSamplesRelated
796
- };
797
- //# sourceMappingURL=chunk-BZ36NJHA.js.map