@sjcrh/proteinpaint-client 2.196.0 → 2.198.0

package/dist/chunk-BOZJHPJP.js

@@ -0,0 +1,216 @@
+import {
+  make_radios
+} from "./chunk-5VOPABBA.js";
+import {
+  initBinConfig
+} from "./chunk-M6EF3WVV.js";
+import {
+  format
+} from "./chunk-NSTL4MY2.js";
+
+// termsetting/handlers/NumRegularBinEditor.ts
+var NumRegularBinEditor = class {
+  constructor(editHandler) {
+    this.dom = {};
+    this.editHandler = editHandler;
+    this.opts = editHandler.opts;
+    this.tw = editHandler.tw;
+    this.termsetting = editHandler.termsetting;
+  }
+  render(div) {
+    this.tw = this.editHandler.tw;
+    this.q = this.getDefaultQ();
+    this.editHandler.handler.density.setBinLines(this.getBoundaryOpts());
+    if (this.dom.binsTable) {
+      if (this.editHandler.dom.binsDiv?.node().contains(this.dom.binsTable.node())) return;
+      else {
+        this.dom.binsTable.remove();
+        delete this.dom.binsTable;
+      }
+    }
+    const binsTable = div.append("table");
+    this.dom.binsTable = binsTable;
+    this.renderBinSizeInput(binsTable.append("tr"));
+    this.renderFirstBinInput(binsTable.append("tr"));
+    this.renderLastBinInputs(binsTable.append("tr"));
+  }
+  getDefaultQ() {
+    if (this.tw.q.type == "regular-bin") return JSON.parse(JSON.stringify(this.tw.q));
+    const t = this.tw.term;
+    const defaultQ = this.termsetting.opts.use_bins_less && t.bins?.less || t.bins?.default;
+    if (defaultQ) return JSON.parse(JSON.stringify(defaultQ));
+    const binConfig = initBinConfig(this.editHandler.handler.density_data);
+    return typeof binConfig == "string" ? JSON.parse(binConfig) : binConfig;
+  }
+  renderBinSizeInput(tr) {
+    const handler = this.editHandler.handler;
+    tr.append("td").style("margin", "5px").style("opacity", 0.5).text("Bin Size");
+    const { min, max } = handler.density_data;
+    const q = this.q;
+    const origBinSize = q.bin_size;
+    this.dom.bin_size_input = tr.append("td").append("input").attr("type", "number").attr("value", "rounding" in q ? format(q.rounding || ".0f")(q.bin_size) : q.bin_size).attr("data-testid", "sjpp-num-reg-bin-editor-size").style("margin-left", "15px").style("width", "100px").style("color", () => q.bin_size > Math.abs(max - min) ? "red" : "").on("change", (event) => {
+      const newValue = Number(event.target.value);
+      if (newValue <= 0) {
+        window.alert("Please enter non-negative bin size.");
+        event.target.value = origBinSize;
+        return;
+      }
+      if ((max - min) / newValue > 100) {
+        window.alert("Bin size too small. Try setting a bigger value.");
+        event.target.value = origBinSize;
+        return;
+      }
+      q.bin_size = newValue;
+      this.dom.bin_size_input.style("color", q.bin_size > max - min ? "red" : newValue != origBinSize ? "green" : "");
+      handler.density.setBinLines(this.getBoundaryOpts());
+    });
+  }
+  renderFirstBinInput(tr) {
+    const handler = this.editHandler.handler;
+    const q = this.q;
+    if (!q.first_bin) throw "missing q.first_bin";
+    tr.append("td").style("margin", "5px").style("opacity", 0.5).text("First Bin Stop");
+    const { min, max } = handler.density_data;
+    const origValue = q.first_bin.stop;
+    this.dom.first_stop_input = tr.append("td").append("input").attr("type", "number").property("value", origValue).style("width", "100px").style("margin-left", "15px").on("change", (event) => {
+      const newValue = Number(event.target.value);
+      if (newValue < min || newValue > max) {
+        window.alert("First bin stop value out of bound.");
+        event.target.value = origValue;
+        return;
+      }
+      this.q.first_bin.stop = newValue;
+      handler.density.setBinLines(this.getBoundaryOpts());
+    });
+    tr.append("td").append("div").style("font-size", ".6em").style("opacity", 0.5).style("display", handler.density.no_density_data ? "none" : "block").text("Indicated by left-most red line. Drag to change.");
+  }
+  renderLastBinInputs(tr) {
+    const handler = this.editHandler.handler;
+    const q = this.q;
+    const isAuto = !q.last_bin || !Number.isFinite(q.last_bin.start);
+    tr.append("td").style("padding-top", "4px").style("opacity", 0.5).style("vertical-align", "top").text("Last Bin Start");
+    const td1 = tr.append("td").style("padding-left", "15px").style("vertical-align", "top");
+    const radio_div = td1.append("div");
+    const radios = make_radios({
+      holder: radio_div,
+      options: [
+        { label: "Automatic", value: "auto", checked: isAuto },
+        { label: "Fixed", value: "fixed", checked: !isAuto }
+      ],
+      callback: (v) => {
+        if (v == "auto") {
+          delete q.last_bin;
+          edit_div.style("display", "none");
+          handler.density.setBinLines(this.getBoundaryOpts());
+          return;
+        }
+        edit_div.style("display", "inline-block");
+        if (this.dom.last_start_input.property("value") == "") {
+          this.dom.last_start_input.property("value", this.tw.q.last_bin?.start || handler.density_data.max);
+        }
+        this.setLastBinStart();
+      }
+    });
+    this.dom.fixed_radio = radios.inputs.filter((_, i) => i === 1);
+    const edit_div = tr.append("td").append("div").style("display", isAuto ? "none" : "inline-block");
+    this.dom.last_start_input = edit_div.append("input").attr("type", "number").property("value", q.last_bin?.start || "").style("width", "100px").on("change", () => this.setLastBinStart());
+    edit_div.append("div").style("font-size", ".6em").style("opacity", 0.5).style("display", handler.density.no_density_data ? "none" : "block").text("Indicated by right-most red line. Drag to change.");
+  }
+  setLastBinStart() {
+    const q = this.q;
+    const { max } = this.editHandler.handler.density_data;
+    const strInput = this.dom.last_start_input.property("value");
+    if (strInput === "") return;
+    const inputValue = Number(strInput);
+    if (q.first_bin && inputValue <= q.first_bin.stop) {
+      window.alert("Last bin start cannot be smaller than first bin stop.");
+      this.dom.last_start_input.property("value", max);
+      return;
+    }
+    if (inputValue > max) {
+      window.alert("Last bin start value out of bound.");
+      this.dom.last_start_input.property("value", max);
+      return;
+    }
+    if (q.last_bin) q.last_bin.start = inputValue;
+    else
+      q.last_bin = {
+        start: inputValue,
+        stopunbounded: true,
+        stopinclusive: false
+      };
+    this.editHandler.handler.density.setBinLines(this.getBoundaryOpts());
+  }
+  getBoundaryOpts() {
+    const { min, max } = this.editHandler.handler.density_data;
+    const binLinesStop = this.q.last_bin?.start ?? max + Math.abs(this.q.first_bin.stop) - Math.min(min, 0);
+    const boundaryValues = [];
+    for (let i = this.q.first_bin.stop; i <= binLinesStop; i = i + this.q.bin_size) {
+      if (this.q.last_bin?.start === i) break;
+      if (i > binLinesStop) boundaryValues[boundaryValues.length - 1].isLastVisibleLine = true;
+      const isDraggable = i === this.q.first_bin.stop || i === this.q.bin_size - 1;
+      boundaryValues.push({ x: i, isDraggable, movesWithLineIndex: !isDraggable ? 0 : -1 });
+    }
+    if (this.q.last_bin) {
+      boundaryValues.push({
+        x: this.q.last_bin.start,
+        isDraggable: true,
+        isLastVisibleLine: true,
+        movesWithLineIndex: -1
+      });
+    }
+    return {
+      values: boundaryValues,
+      callback: (d, value) => {
+        if (d.index === 0) {
+          this.dom.first_stop_input.property("value", value);
+          this.q.first_bin.stop = value;
+        } else {
+          this.editHandler.handler.dom.last_start_input.property("value", value);
+          if (this.q.last_bin) this.q.last_bin.start = value;
+        }
+      }
+    };
+  }
+  getEditedQ(destroyDom = true) {
+    const bin_size = this.dom.bin_size_input.property("value");
+    const config = {
+      mode: "discrete",
+      type: "regular-bin",
+      startinclusive: this.editHandler.boundaryInclusion == "startinclusive",
+      stopinclusive: this.editHandler.boundaryInclusion == "stopinclusive",
+      bin_size: Number(bin_size),
+      first_bin: {
+        startunbounded: true,
+        stop: Number(this.dom.first_stop_input.property("value"))
+      },
+      rounding: bin_size.includes(".") && !bin_size.endsWith(".") ? `.${bin_size.split(".")[1].length}f` : ".0f"
+    };
+    if (this.dom.fixed_radio.property("checked")) {
+      config.last_bin = {
+        start: Number(this.dom.last_start_input.property("value")),
+        stopunbounded: true
+      };
+    }
+    if (destroyDom) {
+      for (const name of Object.keys(this.dom)) {
+        this.dom[name].remove();
+        delete this.dom[name];
+      }
+    }
+    return config;
+  }
+  undoEdits() {
+    this.q = this.getDefaultQ();
+    this.dom.binsTable.selectAll("*").remove();
+    this.renderBinSizeInput(this.dom.binsTable.append("tr"));
+    this.renderFirstBinInput(this.dom.binsTable.append("tr"));
+    this.renderLastBinInputs(this.dom.binsTable.append("tr"));
+    this.editHandler.handler.density.setBinLines(this.getBoundaryOpts());
+  }
+};
+
+export {
+  NumRegularBinEditor
+};
+//# sourceMappingURL=chunk-BOZJHPJP.js.map

package/dist/chunk-CDD7LYJM.js

@@ -0,0 +1,194 @@
+import {
+  sample_match_termvaluesetting
+} from "./chunk-NELOT3NJ.js";
+import {
+  isDictionaryType
+} from "./chunk-I6WR4CG7.js";
+import {
+  __export
+} from "./chunk-HFNDKYVF.js";
+
+// plots/matrix/matrix.data.js
+var matrix_data_exports = {};
+__export(matrix_data_exports, {
+  applyLegendValueFilter: () => applyLegendValueFilter,
+  getMatrixRequestOpts: () => getMatrixRequestOpts,
+  mayRequireToken: () => mayRequireToken,
+  setData: () => setData
+});
+function mayRequireToken(tokenMessage = "") {
+  const message = tokenMessage || this.state.tokenVerificationMessage;
+  if (!message && this.state.hasVerifiedToken) {
+    this.dom.errdiv.style("display", "none").html();
+    this.dom.controls.style("display", this.opts.controls ? "inline-block" : "");
+    this.dom.svg.style("display", "");
+    return false;
+  } else {
+    this.dom.errdiv.style("display", "").html(message || "Requires login");
+    this.dom.controls.style("display", "none");
+    this.dom.svg.style("display", "none");
+    return true;
+  }
+}
+function getMatrixRequestOpts(state, config) {
+  const terms = [];
+  const termgroups = this.chartType == "hierCluster" ? config.termgroups.filter((grp) => grp.type != "hierCluster") : config.termgroups;
+  for (const grp of termgroups) {
+    terms.push(...getNormalizedTwLstCopy(grp.lst));
+  }
+  if (config.divideBy) terms.push(normalizeTwForRequest(structuredClone(config.divideBy)));
+  const opts = {
+    terms,
+    filter: state.filter,
+    filter0: state.filter0,
+    maxGenes: state.config.settings.matrix.maxGenes,
+    /*********** quick fix
+    when the flag is true, set artificially large number to ensure all genes are sent in one query
+    this avoids changing getAnnotatedSampleData()
+    additional non-matrix app that calls getAnnotatedSampleData will NEED THE SAME FIX
+    */
+    termsPerRequest: this.app.vocabApi.termdbConfig.queries?.snvindel?.byisoform?.processTwsInOneQuery ? 1e3 : 1
+  };
+  if (this.chartType == "hierCluster") {
+    opts.isHierCluster = 1;
+  }
+  return opts;
+}
+function getNormalizedTwLstCopy(twlst) {
+  const lst = [];
+  for (const tw of twlst) {
+    if (tw.type && tw.constructor.name != "Object") lst.push(tw);
+    else lst.push(normalizeTwForRequest(tw));
+  }
+  lst.forEach(normalizeTwForRequest);
+  lst.sort(sortTwLst);
+  return lst;
+}
+function normalizeTwForRequest(_tw) {
+  const tw = structuredClone(_tw);
+  if (!tw?.term) return;
+  delete tw.term.category2samplecount;
+  if (isDictionaryType(tw.term.type) && tw.term.type !== "samplelst") delete tw.term.values;
+  return tw;
+}
+function sortTwLst(twa, twb) {
+  const a = twa?.$id || twa.term?.id || twa?.term?.name;
+  const b = twb?.$id || twb.term?.id || twb?.term?.name;
+  return a < b ? -1 : 1;
+}
+async function setData(_data) {
+  const opts = this.currRequestOpts?.matrix || this.getMatrixRequestOpts(this.state, this.config);
+  this.numTerms = opts.terms.length;
+  opts.loadingDiv = this.chartType != "hierCluster" && this.dom.loadingDiv;
+  opts.signal = this.api.getAbortSignal();
+  const data = await this.app.vocabApi.getAnnotatedSampleData(opts, _data);
+  this.data = data;
+  this.origData = structuredClone(this.data);
+  this.sampleIdMap = {};
+  for (const d of this.data.lst) {
+    this.sampleIdMap[d.sample] = d._ref_.label;
+  }
+}
+function applyLegendValueFilter() {
+  const self = this;
+  if (!self.config.legendValueFilter.lst.length && !self.config.legendGrpFilter.lst.length) return;
+  for (const grpFilter of self.config.legendGrpFilter.lst) {
+    if (grpFilter.dt) {
+      const filteredOutCats = /* @__PURE__ */ new Set();
+      for (const oneSampleData of self.origData.lst) {
+        for (const annoForOneTerm of Object.values(oneSampleData)) {
+          if (annoForOneTerm.values) {
+            const newValues = [];
+            for (const v of annoForOneTerm.values) {
+              if (!(grpFilter.dt.includes(v.dt) && (!grpFilter.origin || v.origin == grpFilter.origin))) {
+                newValues.push(v);
+              } else {
+                filteredOutCats.add(v.class);
+              }
+            }
+            annoForOneTerm.values = newValues;
+          }
+        }
+      }
+      grpFilter.filteredOutCats = [...filteredOutCats];
+      for (const oneSampleData of Object.values(self.origData.samples)) {
+        for (const annoForOneTerm of Object.values(oneSampleData)) {
+          if (annoForOneTerm.values)
+            annoForOneTerm.values = annoForOneTerm.values.filter(
+              (v) => !(grpFilter.dt.includes(v.dt) && (!grpFilter.origin || v.origin == grpFilter.origin))
+            );
+        }
+      }
+    }
+  }
+  const geneVariant$ids = Object.values(self.data.refs.byTermId).filter((v) => v.term?.type == "geneVariant").map((v) => v.$id);
+  const data = { samples: {}, lst: [], refs: self.data.refs };
+  const onlyHardFilter = structuredClone(self.config.legendValueFilter);
+  onlyHardFilter.lst = onlyHardFilter.lst.filter(
+    (l) => !l.tvs.legendFilterType || l.tvs.legendFilterType !== "geneVariant_soft"
+  );
+  for (const row of self.origData.lst) {
+    const include = sample_match_termvaluesetting(row, onlyHardFilter, geneVariant$ids);
+    if (include || self.chartType == "hierCluster") {
+      data.samples[row.sample] = row;
+      data.lst.push(row);
+    }
+  }
+  for (const valFilter of self.config.legendValueFilter.lst) {
+    if (valFilter.tvs.legendFilterType !== "geneVariant_soft") continue;
+    const tvsV = valFilter.tvs.values[0];
+    const filteredOutCats = /* @__PURE__ */ new Set();
+    for (const oneSampleData of data.lst) {
+      for (const annoForOneTerm of Object.values(oneSampleData)) {
+        if (annoForOneTerm.values) {
+          const newValues = [];
+          for (const v of annoForOneTerm.values) {
+            if (!(v.dt == tvsV.dt && (!tvsV.origin || v.origin == tvsV.origin) && tvsV.mclasslst.includes(v.class))) {
+              newValues.push(v);
+            } else {
+              filteredOutCats.add(v.class);
+            }
+          }
+          annoForOneTerm.values = newValues;
+        }
+      }
+    }
+    valFilter.filteredOutCats = [...filteredOutCats];
+    for (const oneSampleData of Object.values(data.samples)) {
+      for (const annoForOneTerm of Object.values(oneSampleData)) {
+        if (annoForOneTerm.values)
+          annoForOneTerm.values = annoForOneTerm.values.filter(
+            (v) => !(v.dt == tvsV.dt && (!tvsV.origin || v.origin == tvsV.origin) && tvsV.mclasslst.includes(v.class))
+          );
+      }
+    }
+  }
+  if (self.chartType !== "hierCluster" && geneVariant$ids.length && self.app.vocabApi.vocab?.dslabel == "GDC")
+    remove_empty_sample(data, geneVariant$ids);
+  self.data = data;
+}
+function remove_empty_sample(data) {
+  for (const oneSampleData of data.lst) {
+    let removeSample = true;
+    for (const [key, annoForOneTerm] of Object.entries(oneSampleData)) {
+      if (!annoForOneTerm.values) continue;
+      const annoType = data.refs.byTermId[key].term.type;
+      if (annoType != "geneVariant") continue;
+      if (annoForOneTerm.values.length) removeSample = false;
+    }
+    if (removeSample) {
+      data.lst = data.lst.filter((dl) => dl.sample !== oneSampleData.sample);
+      delete data.samples[parseInt(oneSampleData.sample)];
+    }
+  }
+  return data;
+}
+
+export {
+  mayRequireToken,
+  getMatrixRequestOpts,
+  setData,
+  applyLegendValueFilter,
+  matrix_data_exports
+};
+//# sourceMappingURL=chunk-CDD7LYJM.js.map