@sjcrh/proteinpaint-client 2.185.0 → 2.186.0
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/dist/2dmaf-F5QNP7AQ.js +1371 -0
- package/dist/AIProjectAdmin-ROSQHK6Q.js +827 -0
- package/dist/AIProjectAdmin-ROSQHK6Q.js.map +7 -0
- package/dist/AppHeader-STVCDLET.js +833 -0
- package/dist/BoxPlot-CU7MEBH7.js +1217 -0
- package/dist/CorrelationVolcano-OE4R2GS3.js +617 -0
- package/dist/DE-SR7PJPKI.js +93 -0
- package/dist/DEinput-PRIAIBFH.js +299 -0
- package/dist/DEinput-PRIAIBFH.js.map +7 -0
- package/dist/DifferentialAnalysis-UWTYK7NU.js +241 -0
- package/dist/Disco-IL6REGSA.js +3235 -0
- package/dist/Disco.UI-JHHLS5BA.js +242 -0
- package/dist/DmrPlot-DDP53T3F.js +640 -0
- package/dist/GB-F4LMYMHF.js +1127 -0
- package/dist/GB-F4LMYMHF.js.map +7 -0
- package/dist/GeneExpInput-ZWBC226P.js +363 -0
- package/dist/GeneExpInput-ZWBC226P.js.map +7 -0
- package/dist/HicApp-RVFHTYED.js +2248 -0
- package/dist/NumBinaryEditor-B3FXQAOH.js +268 -0
- package/dist/NumBinaryEditor.unit.spec-75YQJ2U6.js +284 -0
- package/dist/NumContEditor-5PYW3OLY.js +105 -0
- package/dist/NumContEditor.unit.spec-F7ZRDGBN.js +167 -0
- package/dist/NumCustomBinEditor-TBT6GLYQ.js +36 -0
- package/dist/NumCustomBinEditor.unit.spec-6YHU45XV.js +282 -0
- package/dist/NumDiscreteEditor-N6OJYSJA.js +177 -0
- package/dist/NumDiscreteEditor.unit.spec-HQS5RZ6R.js +200 -0
- package/dist/NumRegularBinEditor-HSDDKVNG.js +36 -0
- package/dist/NumRegularBinEditor.unit.spec-33KN2MVM.js +225 -0
- package/dist/NumSplineEditor-XERKOACS.js +190 -0
- package/dist/NumSplineEditor.unit.spec-MPVM6KSC.js +197 -0
- package/dist/NumericDensity-35EKYW3V.js +36 -0
- package/dist/NumericDensity.unit.spec-OR24PPRJ.js +219 -0
- package/dist/NumericHandler-D6ZNGRE3.js +37 -0
- package/dist/NumericHandler.unit.spec-EKPGVSXI.js +217 -0
- package/dist/RunChart2-7DOXOFXV.js +756 -0
- package/dist/SC-APZRV4H6.js +826 -0
- package/dist/SC-APZRV4H6.js.map +7 -0
- package/dist/Volcano-X4ZWK644.js +1344 -0
- package/dist/Volcano-X4ZWK644.js.map +7 -0
- package/dist/WSIViewer-E247ELKN.js +47971 -0
- package/dist/WsiSamplesPlot-3522VRB5.js +163 -0
- package/dist/adSandbox-IDFY5P2P.js +36 -0
- package/dist/alphaGenome-F3W7GJQ5.js +173 -0
- package/dist/app-2HDSFMRM.js +47 -0
- package/dist/app-LIWPFL7C.js +35 -0
- package/dist/app.js +10 -10
- package/dist/bam-TBHHSATL.js +857 -0
- package/dist/barchart-HHFCBOZE.js +45 -0
- package/dist/barchart.events-UQUSSRXB.js +45 -0
- package/dist/barchart.integration.spec-OF3MWFQ5.js +1675 -0
- package/dist/barchart2-XRMPCBBU.js +309 -0
- package/dist/block-5UEORHFB.js +6200 -0
- package/dist/block.init-QSSFUVIT.js +36 -0
- package/dist/block.mds.expressionrank-VBIIJHQF.js +357 -0
- package/dist/block.mds.geneboxplot-KSBHXBNX.js +826 -0
- package/dist/block.mds.junction-FWZWMZJ2.js +1543 -0
- package/dist/block.mds.svcnv-UXORVLH2.js +6799 -0
- package/dist/block.svg-6KIGW4QH.js +162 -0
- package/dist/block.tk.aicheck-DK566Q4C.js +281 -0
- package/dist/block.tk.ase-2GB2VJJ6.js +363 -0
- package/dist/block.tk.bam-RQNOLY52.js +1904 -0
- package/dist/block.tk.bedgraphdot-N4YMZFO4.js +382 -0
- package/dist/block.tk.bigwig.ui-4S7L7D7D.js +209 -0
- package/dist/block.tk.hicstraw-AHFNQKCS.js +821 -0
- package/dist/block.tk.junction-7E6SNQMQ.js +2362 -0
- package/dist/block.tk.junction.textmatrixui-3C5JVYX5.js +197 -0
- package/dist/block.tk.ld-TOUCLT3W.js +97 -0
- package/dist/block.tk.menu-JCV5ORD6.js +1027 -0
- package/dist/block.tk.pgv-CUU22U6M.js +942 -0
- package/dist/brainImaging-MTQTXNNL.js +421 -0
- package/dist/chunk-2UYBBUXK.js +293 -0
- package/dist/chunk-2VPEFXEJ.js +4207 -0
- package/dist/chunk-2YC6ZVE4.js +20377 -0
- package/dist/chunk-2YC6ZVE4.js.map +7 -0
- package/dist/chunk-37MD3Y5G.js +1230 -0
- package/dist/chunk-37MD3Y5G.js.map +7 -0
- package/dist/chunk-3QHIL3V3.js +55 -0
- package/dist/chunk-44VXWKYJ.js +129 -0
- package/dist/chunk-52D6EGUS.js +95 -0
- package/dist/chunk-5FHM3L4I.js +102 -0
- package/dist/chunk-62TF2MCH.js +142 -0
- package/dist/chunk-67QM2NUK.js +6364 -0
- package/dist/chunk-6AAPHEWK.js +676 -0
- package/dist/chunk-6KPGMUHS.js +153 -0
- package/dist/chunk-6WBIZXNI.js +455 -0
- package/dist/chunk-7AAJVXEG.js +302 -0
- package/dist/chunk-AFJRAR4N.js +1271 -0
- package/dist/chunk-BBNO6JLO.js +200 -0
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- package/dist/chunk-LKADRF3Q.js +368 -0
- package/dist/chunk-MAXFRUGM.js +407 -0
- package/dist/chunk-MQN7RYCK.js +37 -0
- package/dist/chunk-OEUI4CYZ.js +470 -0
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- package/dist/chunk-Q3J3F2NU.js +205 -0
- package/dist/chunk-RYCOJY7M.js +188 -0
- package/dist/chunk-RYCOJY7M.js.map +7 -0
- package/dist/chunk-RZBV6474.js +117 -0
- package/dist/chunk-T5V4OC27.js +442 -0
- package/dist/chunk-TXJG4N6S.js +4992 -0
- package/dist/chunk-TXJG4N6S.js.map +7 -0
- package/dist/chunk-UCKSUNSJ.js +335 -0
- package/dist/chunk-W4TLYHZO.js +514 -0
- package/dist/chunk-WPZUXKIB.js +56 -0
- package/dist/chunk-XM47XD6G.js +215 -0
- package/dist/chunk-XVA3UOWD.js +263 -0
- package/dist/chunk-XVA3UOWD.js.map +7 -0
- package/dist/chunk-YIMRBXQK.js +1210 -0
- package/dist/chunk-YIMRBXQK.js.map +7 -0
- package/dist/chunk-YL7VT4QT.js +1159 -0
- package/dist/chunk-YL7VT4QT.js.map +7 -0
- package/dist/chunk-YWBUK4B7.js +291 -0
- package/dist/chunk-YWBUK4B7.js.map +7 -0
- package/dist/chunk-YZHGLSKQ.js +50 -0
- package/dist/chunk-ZGOOZK3I.js +203 -0
- package/dist/chunk-ZH2VP6Q6.js +95 -0
- package/dist/chunk-ZLOQXO5K.js +14 -0
- package/dist/chunk-ZMNDBPJU.js +100 -0
- package/dist/chunk-ZRTW6X3F.js +2784 -0
- package/dist/chunk-ZTT52MBP.js +2681 -0
- package/dist/condition-VUACUQYF.js +330 -0
- package/dist/controls-N4MPSNO4.js +39 -0
- package/dist/controls.config-PRXVODCM.js +37 -0
- package/dist/correlation-QJZUYDFH.js +96 -0
- package/dist/cuminc-JJHXW55V.js +1147 -0
- package/dist/cuminc.integration.spec-IXS2UO2O.js +676 -0
- package/dist/customdata.inputui-DUHO6M6I.js +287 -0
- package/dist/dataDownload-OFB7TYDB.js +328 -0
- package/dist/dataDownload.integration.spec-4HWDQO4C.js +191 -0
- package/dist/databrowser.ui-FGZ5SWG3.js +430 -0
- package/dist/databrowser.ui-FGZ5SWG3.js.map +7 -0
- package/dist/dictionary-BSKN37CP.js +109 -0
- package/dist/dnaMethylation-5QNEEGC6.js +36 -0
- package/dist/dnaMethylation.integration.spec-YIX3JSA7.js +201 -0
- package/dist/dofetch-KFMGQY7G.js +50 -0
- package/dist/e2pca-VX42HDYZ.js +348 -0
- package/dist/ep-B6ZNETLI.js +1254 -0
- package/dist/expclust.gdc.spec-SGECIILQ.js +305 -0
- package/dist/facet-2W5SBPGP.js +519 -0
- package/dist/gb-67KTSE2W.js +86 -0
- package/dist/gb-67KTSE2W.js.map +7 -0
- package/dist/geneExpClustering-6A7364T5.js +247 -0
- package/dist/geneExpression-NAM2UEYN.js +36 -0
- package/dist/geneExpression-WF56ODMZ.js +312 -0
- package/dist/geneExpression.unit.spec-DNE2T3WI.js +100 -0
- package/dist/geneORA-33FK2YOS.js +276 -0
- package/dist/geneVariant-C7PCNBOQ.js +37 -0
- package/dist/geneVariant-REELFRRA.js +39 -0
- package/dist/geneVariant.integration.spec-GNXUGDKL.js +196 -0
- package/dist/genefusion.ui-WO5EPJDS.js +306 -0
- package/dist/geneset-4C6ZLVMN.js +201 -0
- package/dist/geneset-4C6ZLVMN.js.map +7 -0
- package/dist/genomeBrowser.spec-VPAKTUJF.js +279 -0
- package/dist/grin2-AJFEBD43.js +852 -0
- package/dist/grin2-AJFEBD43.js.map +7 -0
- package/dist/grin2-GYHUYNEF.js +1554 -0
- package/dist/gsea-PE5WZ5ZI.js +45 -0
- package/dist/hierCluster-FH6YJHRT.js +61 -0
- package/dist/hierCluster-IFM5I5QN.js +57 -0
- package/dist/hierCluster.config-M57ZIWMB.js +38 -0
- package/dist/hierCluster.integration.spec-Z64RL7MC.js +393 -0
- package/dist/hierCluster.interactivity-CDBAJXOY.js +52 -0
- package/dist/imagePlot-NFEE6IGV.js +161 -0
- package/dist/imagePlot-NFEE6IGV.js.map +7 -0
- package/dist/importPlot-OWKXSK77.js +8 -0
- package/dist/isoformExpression-66XLJG73.js +38 -0
- package/dist/isoformExpression.unit.spec-QJX2IRHL.js +206 -0
- package/dist/launch.adhoc-JCWID253.js +40 -0
- package/dist/leftlabel.sample-5NZ6VQDN.js +257 -0
- package/dist/lollipop-BPFDEM2R.js +169 -0
- package/dist/lollipop-BPFDEM2R.js.map +7 -0
- package/dist/maf-HIS2FQXK.js +450 -0
- package/dist/maftimeline-UPJJQE23.js +591 -0
- package/dist/matrix-62CN2KXR.js +56 -0
- package/dist/matrix-SPEDEB3J.js +61 -0
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- package/dist/matrix.interactivity-OWMHUJCX.js +40 -0
- package/dist/matrix.layout-27QB6MWK.js +42 -0
- package/dist/matrix.renderers-EPXES5E4.js +36 -0
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- package/dist/mavb-M7Y74OWQ.js +730 -0
- package/dist/mds.fimo-WCDFA7HG.js +516 -0
- package/dist/mds.samplescatterplot-ZDHQ3MKJ.js +1548 -0
- package/dist/mds.survivalplot-R74DL2RA.js +481 -0
- package/dist/oncomatrix-MOITJBII.js +293 -0
- package/dist/oncomatrix.spec-NALJBPYS.js +446 -0
- package/dist/plot.2dvaf-IE2EZEFA.js +375 -0
- package/dist/plot.app-HTW6TZEH.js +39 -0
- package/dist/plot.barplot-NCQEPEOY.js +100 -0
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- package/dist/polar-4AUAZHBV.js +184 -0
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- package/dist/profile.spec-TOITKBBZ.js +78 -0
- package/dist/profileBarchart-Z4SYIYBE.js +265 -0
- package/dist/profileForms-RA7XQ2QT.js +438 -0
- package/dist/profilePlot-4BM3XZVK.js +52 -0
- package/dist/profileRadar-EYBESEPI.js +261 -0
- package/dist/profileRadarFacility-FZYTFM26.js +261 -0
- package/dist/proteinView-F6XKT2A5.js +1122 -0
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- package/dist/proteomeAbundance-3RJMRXYI.js +68 -0
- package/dist/proteomeAbundance-3RJMRXYI.js.map +7 -0
- package/dist/proteomeAbundance-65R6M4YQ.js +21 -0
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- package/dist/radar2-I6FN5SUX.js +314 -0
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- /package/dist/{violin.integration.spec-F2UD7BHC.js.map → violin.integration.spec-5EW6PLJX.js.map} +0 -0
- /package/dist/{violin.interactivity-LVDTDEPQ.js.map → violin.interactivity-RI4RURGO.js.map} +0 -0
- /package/dist/{violin.renderer-IIEIUGRI.js.map → violin.renderer-EWU2IFZE.js.map} +0 -0
- /package/dist/{vocabulary-WQRYXBRO.js.map → vocabulary-VLIGC7OP.js.map} +0 -0
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import {
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appInit
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import {
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copyMerge
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} from "./chunk-MVTCBVSX.js";
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// gdc/singlecell.ts
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var gdcGenome = "hg38";
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var gdcDslabel = "GDC";
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async function init(arg, holder, genomes) {
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const plotAppApi = await appInit({
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holder,
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state: {
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genome: gdcGenome,
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dslabel: gdcDslabel,
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termfilter: { filter0: arg.filter0 },
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plots: arg.state?.plots || [{ chartType: "singleCellPlot" }]
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},
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genome: genomes[gdcGenome],
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app: copyMerge({}, arg.opts?.app || {}),
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opts: {
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singleCellPlot: arg.opts?.singleCellPlot || {}
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}
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});
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const api = {
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update: async (updateArg) => {
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if (!plotAppApi) return;
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if ("filter0" in updateArg) {
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plotAppApi.dispatch({
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type: "app_refresh",
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subactions: [
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{
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type: "filter_replace",
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filter0: updateArg.filter0
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]
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});
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} else {
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plotAppApi.dispatch({
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type: "plot_edit",
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id: plotAppApi.getState().plots[0].id,
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config: updateArg
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}
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}
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};
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return api;
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}
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export {
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init
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};
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//# sourceMappingURL=singlecell-VQJ2252L.js.map
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package/dist/snp-ALMKZKL2.js
DELETED
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SearchHandler
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export {
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SearchHandler
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};
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//# sourceMappingURL=snp-ALMKZKL2.js.map
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import {
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SearchHandler
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require_tape
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import {
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__toESM
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} from "./chunk-HFNDKYVF.js";
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// termdb/handlers/test/snp.unit.spec.ts
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var import_tape = __toESM(require_tape(), 1);
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function getGeneSearchWithCoordinates(overrides = {}) {
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return {
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chr: "chr17",
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ref: "G",
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alt: "A",
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fromWhat: "rs1234567",
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start: 7670618,
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stop: 7670619,
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...overrides
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};
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}
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function getGeneSearchWithPos(overrides = {}) {
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return {
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chr: "chr13",
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ref: "T",
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alt: "C",
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fromWhat: "BRCA2:c.68_69delAA",
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pos: 32889612,
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...overrides
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};
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}
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(0, import_tape.default)("\n", function(test) {
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test.comment("-***- termdb/handlers/snp -***-");
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test.end();
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});
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(0, import_tape.default)("selectSnp() should throw when required fields are missing", async (test) => {
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const handler = new SearchHandler();
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handler.callback = () => {
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};
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try {
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await handler.selectSnp({ chr: "chr1", ref: "A", alt: "T" });
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test.fail("Should throw when fromWhat is missing");
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} catch (e) {
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test.match(String(e), /missing chr, ref, alt, or fromWhat/, "Should throw when fromWhat is missing");
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}
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try {
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await handler.selectSnp({ ref: "A", alt: "T", fromWhat: "rs123" });
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test.fail("Should throw when chr is missing");
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} catch (e) {
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test.match(String(e), /missing chr, ref, alt, or fromWhat/, "Should throw when chr is missing");
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}
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try {
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await handler.selectSnp({ chr: "chr1", alt: "T", fromWhat: "rs123" });
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test.fail("Should throw when ref is missing");
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} catch (e) {
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test.match(String(e), /missing chr, ref, alt, or fromWhat/, "Should throw when ref is missing");
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}
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try {
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await handler.selectSnp({ chr: "chr1", ref: "A", fromWhat: "rs123" });
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test.fail("Should throw when alt is missing");
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} catch (e) {
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test.match(String(e), /missing chr, ref, alt, or fromWhat/, "Should throw when alt is missing");
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}
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test.end();
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});
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(0, import_tape.default)("selectSnp() should throw when coordinate is missing", async (test) => {
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const handler = new SearchHandler();
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handler.callback = () => {
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};
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try {
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await handler.selectSnp({
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chr: "chr17",
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ref: "G",
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alt: "A",
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fromWhat: "rs1234567"
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});
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test.fail("Should throw when coordinate is missing");
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} catch (e) {
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test.match(String(e), /missing coordinate of snp/, "Should throw expected message for missing coordinate");
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}
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test.end();
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});
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(0, import_tape.default)("selectSnp() should call callback with term object using start/stop coordinates", async (test) => {
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const handler = new SearchHandler();
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let selected;
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handler.callback = (t) => {
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selected = t;
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};
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const geneSearch = getGeneSearchWithCoordinates();
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await handler.selectSnp(geneSearch);
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test.equal(selected?.id, "rs1234567", "Should set id to fromWhat");
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test.equal(selected?.chr, "chr17", "Should pass chr");
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test.equal(selected?.start, 7670618, "Should pass start coordinate");
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test.equal(selected?.stop, 7670619, "Should pass stop coordinate");
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test.equal(selected?.ref, "G", "Should pass ref");
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test.deepEqual(selected?.alt, ["A"], "Should convert alt string to array");
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test.equal(selected?.name, "rs1234567", "Should set name to fromWhat");
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test.equal(selected?.type, "snp", "Should set type to snp");
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test.end();
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});
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(0, import_tape.default)("selectSnp() should call callback with term object using pos coordinate", async (test) => {
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const handler = new SearchHandler();
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let selected;
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handler.callback = (t) => {
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selected = t;
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};
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const geneSearch = getGeneSearchWithPos();
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await handler.selectSnp(geneSearch);
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test.equal(selected?.id, "BRCA2:c.68_69delAA", "Should set id to fromWhat");
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test.equal(selected?.chr, "chr13", "Should pass chr");
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test.equal(selected?.start, 32889611, "Should convert pos-1 to start");
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test.equal(selected?.stop, 32889612, "Should set stop to pos");
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test.equal(selected?.ref, "T", "Should pass ref");
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test.deepEqual(selected?.alt, ["C"], "Should convert alt string to array");
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test.equal(selected?.name, "BRCA2:c.68_69delAA", "Should set name to fromWhat");
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test.equal(selected?.type, "snp", "Should set type to snp");
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test.end();
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});
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(0, import_tape.default)("selectSnp() should handle alt as array when already in array format", async (test) => {
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const handler = new SearchHandler();
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let selected;
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handler.callback = (t) => {
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selected = t;
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};
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const geneSearch = getGeneSearchWithCoordinates({ alt: ["A", "T"] });
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await handler.selectSnp(geneSearch);
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test.deepEqual(selected?.alt, ["A", "T"], "Should preserve alt array when provided as array");
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test.end();
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});
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(0, import_tape.default)("selectSnp() should handle various chromosome formats", async (test) => {
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const handler = new SearchHandler();
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const chromosomes = ["chr1", "chr22", "chrX", "chrY", "chrM"];
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for (const chr of chromosomes) {
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let selected;
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handler.callback = (t) => {
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selected = t;
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};
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const geneSearch = getGeneSearchWithCoordinates({ chr });
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await handler.selectSnp(geneSearch);
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test.equal(selected?.chr, chr, `Should handle chromosome ${chr}`);
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}
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test.end();
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});
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//# sourceMappingURL=snp.unit.spec-GJQBAHGQ.js.map
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import {
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makeSnpSelect,
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mayRestrictAncestry
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} from "./chunk-T5BDYCFO.js";
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import "./chunk-7OYOC7XY.js";
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import {
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addGeneSearchbox,
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filterInit,
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getNormalRoot
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} from "./chunk-YWUVCXFS.js";
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import "./chunk-HJ6L54YS.js";
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import "./chunk-UCLS2SVB.js";
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import "./chunk-HFNDKYVF.js";
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// termsetting/handlers/snplocus.ts
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var term_name = "Variants in a locus";
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function getHandler(self) {
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return {
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getPillName() {
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return self.term.name;
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},
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getPillStatus() {
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if (!self.term || !self.q) return;
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if (!self.term.snps) throw `Missing term.snps [snplocs.ts getPillStatus()]`;
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let text = `${self.q.chr}:${self.q.start}-${self.q.stop}, ${self.term.snps.length} variant${self.term.snps.length > 1 ? "s" : ""}`;
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if (self.term.reachedVariantLimit) {
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text += '<span style="margin-left: 6px; background:#aaa; font-size:1em;font-style: normal; border-radius: 7px;color:white;padding:0px 5px;">⚠<span>';
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}
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return { text };
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},
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validateQ(data) {
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validateQ(data);
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},
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async showEditMenu(div) {
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await makeEditMenu(self, div);
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}
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/* no need for postMain()
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cache file contains all samples,
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variants in a cache file is only determined by locus range and info fields
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thus no need to regenerate cache file upon subcohort or filter change via pill.main()
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async postMain() {
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if (self.q && self.q.chr) {
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await validateInput(self)
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}
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}
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*/
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};
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}
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async function makeEditMenu(self, div0) {
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const div = div0.append("div").style("margin", "15px");
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const select_ancestry = await mayRestrictAncestry(self, div);
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const coordResult = addGeneSearchbox({
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genome: self.opts.genomeObj,
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tip: self.dom.tip2,
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row: div.append("div").style("margin-top", "20px"),
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defaultCoord: self.q && self.q.chr ? { chr: self.q.chr, start: self.q.start, stop: self.q.stop } : void 0
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});
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div.select(".sja_genesearchinput").style("margin", "0px");
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div.append("span").style("margin", "5px 0px").style("display", "inline-block").style("opacity", 0.4).style("font-size", ".7em").html(
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'"Gene": Gene name (e.g. AKT1)</br>"Position": chr:start-stop (e.g. chr1:5000-6000)</br>"dbSNP": dbSNP accession (e.g. rs1042522)'
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);
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await mayDisplayVariantFilter(self, self.q?.variant_filter, div);
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const [input_AFcutoff, select_alleleType, select_geneticModel] = makeSnpSelect(
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div.append("div").attr("class", "sjpp-snp-select").style("margin-top", "15px"),
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self,
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"snplocus"
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);
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if (self.usecase.target == "dataDownload") div.select(".sjpp-snp-select").style("display", "none");
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const btnRow = div.append("div").style("margin-top", "15px");
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btnRow.append("button").style("margin-top", "15px").text("Submit").on("click", async (event) => {
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if (!coordResult.chr) return window.alert("Invalid coordinate");
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event.target.disabled = true;
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event.target.innerHTML = "Validating input...";
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if (self.term) {
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} else {
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self.term = { id: makeId() };
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}
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if (!self.q) self.q = {};
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self.term.type = "snplocus";
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self.q.chr = coordResult.chr;
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self.q.start = coordResult.start;
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self.q.stop = coordResult.stop;
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self.term.name = term_name;
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delete self.term.snps;
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self.q.variant_filter = getNormalRoot(self.variantFilter.active);
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await validateInput(self);
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{
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const v = Number(input_AFcutoff.property("value"));
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self.q.AFcutoff = v < 0 || v >= 100 ? 5 : v;
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}
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self.q.alleleType = select_alleleType.property("selectedIndex");
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self.q.geneticModel = select_geneticModel.property("selectedIndex");
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if (select_ancestry) {
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self.q.restrictAncestry = select_ancestry.node().options[select_ancestry.property("selectedIndex")].__ancestry_obj;
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}
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self.api.runCallback();
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});
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btnRow.append("span").style("padding-left", "15px").style("opacity", 0.8).style("font-size", ".8em").text(
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self.usecase.target == "dataDownload" ? "" : "Variants will be treated individually in separate regression models"
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);
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}
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async function validateInput(self) {
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const data = await self.vocabApi.validateSnps(self.q);
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if (data.error) throw data.error;
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self.q.cacheid = data.cacheid;
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self.term.snps = data.snps;
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self.term.reachedVariantLimit = data.reachedVariantLimit;
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}
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function validateQ(data) {
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const q = data.q;
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if (!Number.isFinite(q.AFcutoff)) throw "AFcutoff is not number";
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if (q.AFcutoff < 0 || q.AFcutoff > 100) throw "AFcutoff is not within 0 to 100";
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if (![0, 1].includes(q.alleleType)) throw "alleleType value is not one of 0/1";
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if (![0, 1, 2, 3].includes(q.geneticModel)) throw "geneticModel value is not one of 0/1";
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if (!q.chr) throw "chr missing";
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if (!Number.isInteger(q.start)) throw "start coordinate is not integer";
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if (!Number.isInteger(q.stop)) throw "stop coordinate is not integer";
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if (q.start < 0) throw "start < 0";
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if (q.stop <= q.start) throw "stop <= start";
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}
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async function fillTW(tw, vocabApi) {
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try {
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validateQ(tw);
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} catch (e) {
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throw "snplocus validateQ(): " + e;
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}
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if (!tw.term.name) tw.term.name = term_name;
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if (tw.id == void 0 || tw.id == "") {
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if (tw.term.id == void 0 || tw.term.id == "") {
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tw.term.id = makeId();
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}
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tw.id = tw.term.id;
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} else {
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if (tw.term.id == void 0 || tw.term.id == "") {
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tw.term.id = tw.id;
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}
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}
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await validateInput({
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term: tw.term,
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q: tw.q,
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vocabApi
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});
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}
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function makeId() {
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return "snplocus" + Math.random();
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}
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async function mayDisplayVariantFilter(self, filterInState, holder, callback2) {
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if (!self.variantFilter) {
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self.variantFilter = await self.vocabApi.get_variantFilter();
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}
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if (!self.variantFilter.terms) {
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return;
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}
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if (!self.variantFilter.opts) throw "variantFilter.opts{} missing";
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if (!self.variantFilter.filter) throw ".filter missing from variantFilter{}";
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if (!Array.isArray(self.variantFilter.terms) || self.variantFilter.terms.length == 0)
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throw "variantFilter.terms[] is not non-empty array";
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if (filterInState) {
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self.variantFilter.active = JSON.parse(JSON.stringify(filterInState));
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} else {
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self.variantFilter.active = JSON.parse(JSON.stringify(self.variantFilter.filter));
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}
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const div = holder.append("div").style("margin-top", "15px");
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div.append("span").text("VARIANT FILTERS").style("font-size", ".8em").style("opacity", 0.5);
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const filterBody = div.append("div");
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filterInit({
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joinWith: self.variantFilter.opts.joinWith,
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emptyLabel: "+Variant Filter",
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holder: filterBody,
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vocab: { terms: self.variantFilter.terms },
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callback: async (filter) => {
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self.variantFilter.active = filter;
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if (callback2) await callback2();
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}
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}).main(self.variantFilter.active);
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}
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export {
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fillTW,
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getHandler
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};
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//# sourceMappingURL=snplocus-WCNCMFWZ.js.map
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import {
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font
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} from "./chunk-YWUVCXFS.js";
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import "./chunk-HJ6L54YS.js";
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import "./chunk-3QBZ2Y77.js";
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import "./chunk-HYOEWQ5P.js";
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import "./chunk-FN5XPUPH.js";
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import "./chunk-G6O3URDN.js";
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import "./chunk-LSEFWW72.js";
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import "./chunk-KWM6B3NL.js";
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import "./chunk-UCLS2SVB.js";
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import "./chunk-6ZCHECOT.js";
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import "./chunk-MVTCBVSX.js";
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import "./chunk-2K5DSRBJ.js";
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import "./chunk-X4NI4JLQ.js";
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import "./chunk-L4QG7XZE.js";
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import "./chunk-DQC5FFGV.js";
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import "./chunk-UWYCEYML.js";
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import "./chunk-7UHUOC6F.js";
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import "./chunk-ZYY54HBU.js";
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import "./chunk-EGWVYY7K.js";
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import {
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IN_frame,
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exoncolor
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} from "./chunk-AMYSEKPF.js";
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import "./chunk-TV74I3Y5.js";
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import "./chunk-KSGA62R2.js";
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import "./chunk-LOZEKOES.js";
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import "./chunk-TOU7EVFQ.js";
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import "./chunk-OAWQ6LOO.js";
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import "./chunk-KYBIQBXE.js";
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import "./chunk-I6Y4O3RR.js";
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import "./chunk-OMR2DT66.js";
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import "./chunk-HFNDKYVF.js";
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// src/spliceevent.a53ss.diagram.js
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var junctionBcolor = "#990000";
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var color_truncateexon = "#00A352";
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function spliceevent_a53ss_diagram_default(arg) {
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const evt = arg.event;
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if (!evt) {
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arg.holder.text(".event missing");
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return;
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}
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if (evt.a5ss == void 0 && evt.a3ss == void 0) {
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arg.holder.text("not a5ss or a3ss");
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return;
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}
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const exonwidth = 30;
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const intronwidth = 30;
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const exonheight = 20;
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const distfontsize = exonheight - 5;
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const junctionheight = 20;
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const xpad = 30;
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const ypad = 20;
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const svg = arg.holder.append("svg");
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const g = svg.append("g").attr("transform", "translate(" + xpad + "," + ypad + ")");
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const distlabel = evt.sitedist + " nt";
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let distlabelw;
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g.append("text").text(distlabel).attr("font-size", distfontsize).attr("font-family", font).each(function() {
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distlabelw = this.getBBox().width;
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}).remove();
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const distlabelpad = 5;
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let leftinexon = false;
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let rightinexon = false;
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let leftinintron = false;
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let rightinintron = false;
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if (evt.a5ss) {
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if (evt.altinexon) leftinexon = true;
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else leftinintron = true;
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} else {
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if (evt.altinexon) rightinexon = true;
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else rightinintron = true;
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}
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let x = 0;
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let intronstart;
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let intronstop;
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|
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g.append("rect").attr("fill", exoncolor).attr("stroke", exoncolor).attr("x", x).attr("y", junctionheight).attr("width", exonwidth).attr("height", exonheight).attr("shape-rendering", "crispEdges");
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g.append("text").text("e" + (evt.exon5idx + 1)).attr("text-anchor", "middle").attr("x", x + exonwidth / 2).attr("y", junctionheight + exonheight / 2).attr("fill", "white").attr("dominant-baseline", "central").attr("font-size", distfontsize).attr("font-family", font);
|
|
80
|
-
x += exonwidth;
|
|
81
|
-
if (leftinexon) {
|
|
82
|
-
g.append("rect").attr("fill", color_truncateexon).attr("stroke", color_truncateexon).attr("x", x).attr("y", junctionheight).attr("width", distlabelw + distlabelpad * 2).attr("height", exonheight).attr("shape-rendering", "crispEdges");
|
|
83
|
-
g.append("text").text(distlabel).attr("text-anchor", "middle").attr("x", x + distlabelw / 2 + distlabelpad).attr("y", junctionheight + exonheight / 2).attr("fill", "white").attr("dominant-baseline", "central").attr("font-size", distfontsize).attr("font-family", font);
|
|
84
|
-
x += distlabelw + distlabelpad * 2;
|
|
85
|
-
}
|
|
86
|
-
intronstart = x;
|
|
87
|
-
if (leftinintron || rightinintron) {
|
|
88
|
-
if (leftinintron) {
|
|
89
|
-
} else {
|
|
90
|
-
x += intronwidth;
|
|
91
|
-
}
|
|
92
|
-
g.append("rect").attr("fill", "none").attr("stroke", exoncolor).attr("x", x).attr("y", junctionheight).attr("width", distlabelw + distlabelpad * 2).attr("height", exonheight).attr("shape-rendering", "crispEdges");
|
|
93
|
-
g.append("text").text(distlabel).attr("text-anchor", "middle").attr("x", x + distlabelw / 2 + distlabelpad).attr("y", junctionheight + exonheight / 2).attr("font-size", distfontsize).attr("font-family", font).attr("dominant-baseline", "central");
|
|
94
|
-
x += distlabelw + distlabelpad * 2;
|
|
95
|
-
if (leftinintron) {
|
|
96
|
-
x += intronwidth;
|
|
97
|
-
}
|
|
98
|
-
} else {
|
|
99
|
-
x += intronwidth;
|
|
100
|
-
}
|
|
101
|
-
intronstop = x;
|
|
102
|
-
g.append("line").attr("x1", intronstart + (leftinintron ? distlabelw + distlabelpad * 2 : 0)).attr("y1", junctionheight + exonheight / 2).attr("x2", intronstop - (rightinintron ? distlabelw + distlabelpad * 2 : 0)).attr("y2", junctionheight + exonheight / 2).attr("stroke", exoncolor).attr("shape-rendering", "crispEdges");
|
|
103
|
-
if (rightinexon) {
|
|
104
|
-
g.append("rect").attr("fill", color_truncateexon).attr("stroke", color_truncateexon).attr("x", x).attr("y", junctionheight).attr("width", distlabelw + distlabelpad * 2).attr("height", exonheight).attr("shape-rendering", "crispEdges");
|
|
105
|
-
g.append("text").text(distlabel).attr("text-anchor", "middle").attr("x", x + distlabelw / 2 + distlabelpad).attr("y", junctionheight + exonheight / 2).attr("fill", "white").attr("dominant-baseline", "central").attr("font-size", distfontsize).attr("font-family", font);
|
|
106
|
-
x += distlabelw + distlabelpad * 2;
|
|
107
|
-
}
|
|
108
|
-
g.append("rect").attr("fill", exoncolor).attr("stroke", exoncolor).attr("x", x).attr("y", junctionheight).attr("width", exonwidth).attr("height", exonheight).attr("shape-rendering", "crispEdges");
|
|
109
|
-
g.append("text").text("e" + (evt.exon5idx + 1 + 1)).attr("text-anchor", "middle").attr("x", x + exonwidth / 2).attr("y", junctionheight + exonheight / 2).attr("fill", "white").attr("dominant-baseline", "central").attr("font-size", distfontsize).attr("font-family", font);
|
|
110
|
-
{
|
|
111
|
-
let x1, x2;
|
|
112
|
-
if (leftinexon || leftinintron) {
|
|
113
|
-
x2 = intronstop;
|
|
114
|
-
if (leftinexon) {
|
|
115
|
-
x1 = intronstart - distlabelw - distlabelpad * 2;
|
|
116
|
-
} else {
|
|
117
|
-
x1 = intronstart + distlabelw + distlabelpad * 2;
|
|
118
|
-
}
|
|
119
|
-
} else {
|
|
120
|
-
x1 = intronstart;
|
|
121
|
-
if (rightinintron) {
|
|
122
|
-
x2 = intronstop - distlabelw - distlabelpad * 2;
|
|
123
|
-
} else {
|
|
124
|
-
x2 = intronstop + distlabelw + distlabelpad * 2;
|
|
125
|
-
}
|
|
126
|
-
}
|
|
127
|
-
g.append("path").attr("d", "M" + x1 + "," + junctionheight + "L" + (x1 + x2) / 2 + ",0L" + x2 + "," + junctionheight).attr("stroke", junctionBcolor).attr("fill", "none");
|
|
128
|
-
g.append("text").text(evt.junctionB.v + (evt.frame != void 0 ? evt.frame == IN_frame ? ", in frame" : ",out of frame" : "")).attr("x", (x1 + x2) / 2).attr("y", -1).attr("text-anchor", "middle").attr("font-size", distfontsize).attr("fill", junctionBcolor);
|
|
129
|
-
}
|
|
130
|
-
let jAreadcounttext;
|
|
131
|
-
{
|
|
132
|
-
const line = g.append("path").attr(
|
|
133
|
-
"d",
|
|
134
|
-
"M" + intronstart + "," + (junctionheight + exonheight) + "L" + (intronstart + intronstop) / 2 + "," + (junctionheight * 2 + exonheight) + "L" + intronstop + "," + (junctionheight + exonheight)
|
|
135
|
-
).attr("stroke", exoncolor).attr("fill", "none");
|
|
136
|
-
const nj = evt.junctionA;
|
|
137
|
-
if (nj) {
|
|
138
|
-
jAreadcounttext = g.append("text").text(nj.v).attr("x", (intronstart + intronstop) / 2).attr("y", junctionheight * 2 + exonheight + 1).attr("text-anchor", "middle").attr("font-size", distfontsize).attr("dominant-baseline", "hanging");
|
|
139
|
-
} else {
|
|
140
|
-
line.attr("stroke-dasharray", "3,3");
|
|
141
|
-
}
|
|
142
|
-
}
|
|
143
|
-
svg.attr("width", xpad * 2 + exonwidth * 2 + intronwidth + distlabelw + distlabelpad * 2).attr("height", ypad * 2 + junctionheight * 2 + exonheight);
|
|
144
|
-
return jAreadcounttext;
|
|
145
|
-
}
|
|
146
|
-
export {
|
|
147
|
-
spliceevent_a53ss_diagram_default as default
|
|
148
|
-
};
|
|
149
|
-
//# sourceMappingURL=spliceevent.a53ss.diagram-4Q4JF4RX.js.map
|