@sjcrh/proteinpaint-client 2.184.0 → 2.185.0

package/dist/chunk-3T2PCWII.js

@@ -0,0 +1,442 @@
+import {
+  getDefaultViolinSettings
+} from "./chunk-YQVEBFGT.js";
+import {
+  getDefaultScatterSettings
+} from "./chunk-UVPAZM3G.js";
+import {
+  getDefaultBoxplotSettings
+} from "./chunk-MHCTLVGE.js";
+import {
+  PlotBase,
+  Tabs,
+  defaultUiLabels,
+  fillTermWrapper,
+  filterRxCompInit,
+  getDefaultBarSettings,
+  term0_term2_defaultQ
+} from "./chunk-YWUVCXFS.js";
+import {
+  importPlot
+} from "./chunk-3QBZ2Y77.js";
+import {
+  Menu
+} from "./chunk-HYOEWQ5P.js";
+import {
+  copyMerge,
+  getCompInit
+} from "./chunk-MVTCBVSX.js";
+import {
+  isNumericTerm
+} from "./chunk-EGWVYY7K.js";
+
+// plots/summary.ts
+var SummaryPlot = class _SummaryPlot extends PlotBase {
+  constructor(opts, api) {
+    super(opts, api);
+    this.components = {};
+    // expected class-specific props
+    this.chartsByType = {};
+    this.configTermKeys = ["term", "term0", "term2"];
+    this.type = _SummaryPlot.type;
+    this.dom = this.getDom(opts);
+    this.tabsData = this.getTabsData();
+    this.chartToggles = new Tabs({ holder: this.dom.chartToggles, tabs: this.tabsData, noContent: true });
+    this.components = {
+      plots: {}
+    };
+  }
+  static {
+    this.type = "summary";
+  }
+  preApiFreeze(api) {
+    api.getError = () => {
+      return this.error;
+    };
+  }
+  getDom(opts) {
+    const holder = opts.holder;
+    holder.header.style("padding", 0);
+    const paneTitleDiv = holder.header.append("div").style("display", "inline-block").style("color", "#555").style("padding-left", "7px");
+    return {
+      tip: new Menu({ padding: "0px" }),
+      holder,
+      body: holder.body.style("white-space", "nowrap").style("overflow-x", "auto"),
+      // will hold no data notice or the page title in multichart views
+      errdiv: holder.body.append("div").attr("class", "sja_errorbar").style("display", "none").style("padding", "5px"),
+      loading: holder.body.append("div").style("display", "none").style("padding", "5px").html("Loading ..."),
+      // dom.viz will hold the rendered view
+      viz: holder.body.append("div"),
+      plotDivs: {},
+      paneTitleDiv,
+      paneTitleText: paneTitleDiv.append("div").classed("sjpp-term-header", true).style("display", "inline-block").style("vertical-align", "sub"),
+      chartToggles: paneTitleDiv.append("div").style("display", "inline-block").style("margin-left", "10px"),
+      localRecoverDiv: paneTitleDiv.append("div").style("display", "inline-block"),
+      filterDiv: holder.header.append("div").style("display", "inline-block").style("zoom", 0.9)
+    };
+  }
+  getTabsData() {
+    const callback = (event, tab) => this.tabClickCallback(event, tab);
+    return [
+      {
+        childType: "barchart",
+        label: "Barchart",
+        isVisible: () => true,
+        disabled: () => false,
+        getConfig: async () => {
+          if (!this.config) return;
+          const config = { id: this.id, childType: "barchart" };
+          const { term, term2 } = this.config || {};
+          if (term) {
+            const mode = isNumericTerm(term?.term) ? "discrete" : term?.q.mode || "discrete";
+            config.term = await this.getWrappedTermCopy(term, mode);
+          }
+          if (term2) {
+            const mode = isNumericTerm(term2.term) ? "discrete" : term2.q.mode || "discrete";
+            config.term2 = await this.getWrappedTermCopy(term2, mode);
+          }
+          return config;
+        },
+        active: true,
+        callback
+      },
+      {
+        childType: "violin",
+        label: "Violin",
+        disabled: () => false,
+        isVisible: () => isNumericTerm(this.config?.term?.term) || isNumericTerm(this.config?.term2?.term),
+        getConfig: async () => {
+          const term = this.config?.term;
+          const term2 = this.config.term2;
+          let _term, _term2;
+          this.violinContTerm = isNumericTerm(term?.term) ? "term" : "term2";
+          if (this.violinContTerm && this.violinContTerm === "term" || term.q?.mode == "continuous") {
+            _term = await this.getWrappedTermCopy(term, "continuous");
+            _term2 = await this.getWrappedTermCopy(term2, "discrete");
+            this.violinContTerm = "term";
+          } else if (this.violinContTerm && this.violinContTerm === "term2" || term2?.q?.mode == "continuous") {
+            _term = await this.getWrappedTermCopy(term, "discrete");
+            _term2 = await this.getWrappedTermCopy(term2, "continuous");
+            this.violinContTerm = "term2";
+          } else if (term2?.q?.mode == "discrete") {
+            _term = await this.getWrappedTermCopy(term, "discrete");
+            _term2 = await this.getWrappedTermCopy(term2, "continuous");
+            this.violinContTerm = "term2";
+          } else {
+            _term = await this.getWrappedTermCopy(term, "continuous");
+            _term2 = await this.getWrappedTermCopy(term2, "discrete");
+            this.violinContTerm = "term";
+          }
+          const config = { childType: "violin", term: _term, term2: _term2 };
+          return config;
+        },
+        active: false,
+        callback
+      },
+      {
+        childType: "boxplot",
+        label: "Boxplot",
+        disabled: () => false,
+        isVisible: () => isNumericTerm(this.config?.term?.term) || isNumericTerm(this.config?.term2?.term),
+        getConfig: async () => {
+          const _term = this.config?.term;
+          const _term2 = this.config.term2;
+          let termMode = "continuous", term2Mode = "discrete";
+          this.boxContTerm = isNumericTerm(_term?.term) ? "term" : "term2";
+          if (this.boxContTerm && this.boxContTerm === "term" || _term.q?.mode == "continuous") {
+            termMode = "continuous";
+            term2Mode = "discrete";
+            this.boxContTerm = "term";
+          } else if (this.boxContTerm && this.boxContTerm === "term2" || _term2?.q?.mode == "continuous") {
+            termMode = "discrete";
+            term2Mode = "continuous";
+            this.boxContTerm = "term2";
+          } else if (_term2?.q?.mode == "discrete") {
+            termMode = "discrete";
+            term2Mode = "continuous";
+            this.boxContTerm = "term2";
+          }
+          const term = await this.getWrappedTermCopy(_term, termMode);
+          const term2 = await this.getWrappedTermCopy(_term2, term2Mode);
+          const config = {
+            childType: "boxplot",
+            term,
+            term2
+          };
+          return config;
+        },
+        active: false,
+        callback
+      },
+      {
+        childType: "sampleScatter",
+        label: "Scatter",
+        disabled: () => false,
+        isVisible: () => {
+          return isNumericTerm(this.config?.term.term) && isNumericTerm(this.config?.term2?.term);
+        },
+        getConfig: async () => {
+          const _term = await this.getWrappedTermCopy(this.config?.term, "continuous");
+          const _term2 = await this.getWrappedTermCopy(this.config?.term2, "continuous");
+          const config = {
+            childType: "sampleScatter",
+            term: _term,
+            term2: _term2,
+            groups: [],
+            term0: this.config.term0
+          };
+          return config;
+        },
+        active: false,
+        callback
+      }
+    ];
+  }
+  async init(appState) {
+    const state = this.getState(appState);
+    const config = structuredClone(state.config);
+    this.initUi(this.opts, config);
+    this.components.filter = await filterRxCompInit({
+      app: this.app,
+      vocabApi: this.app.vocabApi,
+      parentId: this.id,
+      holder: this.dom.filterDiv,
+      hideLabel: true,
+      emptyLabel: "+Add new filter",
+      callback: (filter) => {
+        this.app.dispatch({
+          id: this.id,
+          type: "plot_edit",
+          config: { filter }
+        });
+      }
+    });
+  }
+  reactsTo(action) {
+    if (action.type.includes("cache_termq")) return true;
+    if (action.type.startsWith("plot_")) {
+      if (action.type.startsWith("plot_")) {
+        return action.id === this.id || action.id == this.parentId;
+      }
+    }
+    if (action.type.startsWith("filter")) return true;
+    if (action.type.startsWith("cohort")) return true;
+    if (action.type == "app_refresh") return true;
+    return false;
+  }
+  getState(appState) {
+    const config = appState.plots.find((p) => p.id === this.id);
+    if (!config) {
+      throw `No plot with id='${this.id}' found. Did you set this.id before this.api = getComponentApi(this)?`;
+    }
+    return {
+      termfilter: appState.termfilter,
+      config,
+      // quick fix to skip history tracking as needed
+      _scope_: appState._scope_
+    };
+  }
+  async main() {
+    delete this.error;
+    this.dom.errdiv.style("display", "none").html("");
+    this.dom.loading.style("display", "");
+    this.config = await this.getMutableConfig();
+    this.maySetSandboxHeader();
+    if (!this.components.plots[this.config.childType]) {
+      await this.setComponent(this.config);
+    }
+    this.dom.loading.style("display", "none");
+    this.render();
+    const activeTabIndex = this.tabsData.findIndex((tab) => tab.childType == this.config.childType);
+    this.chartToggles.update(activeTabIndex);
+    const numVisTabs = this.tabsData.filter((d) => d.isVisible()).length;
+    if (numVisTabs > 1) this.dom.chartToggles.style("display", "inline-block");
+    else this.dom.chartToggles.style("display", "none");
+  }
+  maySetSandboxHeader() {
+    const { term, term2, headerText, assayCohortTitle } = this.config;
+    const mainTerm = term.getTitleText?.() || term.term.name;
+    const _headerPretext = headerText ? `${headerText} ` : "";
+    const _headerSuffix = assayCohortTitle ? ` (${assayCohortTitle})` : "";
+    const titleBase = mainTerm + _headerSuffix;
+    if (term2?.type) {
+      this.dom.paneTitleText.html(`${_headerPretext}${term2.getTitleText?.() || term2.term.name} vs ${titleBase}`);
+    } else {
+      this.dom.paneTitleText.html(`${_headerPretext}${titleBase}`);
+    }
+  }
+  async setComponent(config) {
+    const _ = await importPlot(config.childType, `unsupported childType='${config.childType}'`);
+    this.dom.plotDivs[config.childType] = this.dom.viz.append("div");
+    this.components.plots[config.childType] = await _.componentInit({
+      app: this.app,
+      holder: this.dom.plotDivs[config.childType],
+      id: this.id,
+      parent: this.api
+    });
+  }
+  destroy() {
+    this.dom.holder.app_div.selectAll("*").remove();
+    this.dom.holder.app_div.remove();
+    for (const key in this.dom) {
+      delete this.dom[key];
+    }
+  }
+  initUi(opts, config) {
+    this.dom.paneTitleText.html(config.term.term.name);
+    this.chartToggles.main();
+  }
+  async tabClickCallback(event, tab) {
+    if (!tab || !tab.getConfig) return;
+    let config;
+    try {
+      this.dom.viz.style("display", "none");
+      this.dom.loading.style("display", "");
+      config = await tab.getConfig();
+      this.dom.loading.style("display", "none");
+      this.dom.viz.style("display", "");
+      if (config)
+        this.app.dispatch({
+          type: "plot_edit",
+          id: this.id,
+          config
+        });
+    } catch (e) {
+      this.dom.loading.style("display", "none");
+      this.error = e;
+      this.dom.errdiv.style("display", "").html(`Error: ${e.message || e.error || e}`);
+    }
+  }
+  async getWrappedTermCopy(term, mode) {
+    if (!term) return;
+    const tw = structuredClone(term);
+    tw.q.mode = mode;
+    await fillTermWrapper(tw, this.app.vocabApi);
+    return tw;
+  }
+  render() {
+    for (const childType of Object.keys(this.components.plots)) {
+      const chart = this.components.plots[childType];
+      if (chart.type != this.config.childType) {
+        this.dom.plotDivs[chart.type].style("display", "none");
+      }
+    }
+    this.dom.plotDivs[this.config.childType].style("display", "");
+  }
+  getChartImages() {
+    const chart = this.components.plots[this.config.childType];
+    if (chart?.getChartImages) {
+      return chart.getChartImages();
+    }
+    return null;
+  }
+};
+var summaryInit = getCompInit(SummaryPlot);
+var componentInit = summaryInit;
+async function getPlotConfig(opts, app) {
+  if (!opts.term) throw "summary getPlotConfig: opts.term{} missing";
+  try {
+    opts.term = await fillTermWrapper(
+      opts.term,
+      app.vocabApi,
+      opts.term.q || { geneVariant: { type: "predefined-groupset" } }
+    );
+    if (opts.term2)
+      opts.term2 = await fillTermWrapper(
+        opts.term2,
+        app.vocabApi,
+        opts.term2.bins || opts.term2.q ? void 0 : term0_term2_defaultQ
+      );
+    if (opts.term0)
+      opts.term0 = await fillTermWrapper(
+        opts.term0,
+        app.vocabApi,
+        opts.term0.bins || opts.term0.q ? void 0 : term0_term2_defaultQ
+      );
+    if (opts.colorTW) opts.colorTW = await fillTermWrapper(opts.colorTW, app.vocabApi);
+    if (opts.shapeTW) opts.shapeTW = await fillTermWrapper(opts.shapeTW, app.vocabApi);
+    if (opts.scaleDotTW) opts.scaleDotTW = await fillTermWrapper(opts.scaleDotTW, app.vocabApi);
+  } catch (e) {
+    if (e.stack) console.log(e.stack);
+    throw `${e} [summary getPlotConfig()]`;
+  }
+  const config = {
+    chartType: "summary",
+    childType: "barchart",
+    //id: opts.term.term.id,
+    term: opts.term,
+    groups: [],
+    controlLabels: Object.assign({}, defaultUiLabels, app.vocabApi.termdbConfig.uiLabels || {}),
+    settings: {
+      controls: {
+        isOpen: false
+      },
+      common: {
+        use_logscale: false,
+        // flag for y-axis scale type, 0=linear, 1=log
+        use_percentage: false
+        // Move to barchart settings
+        // barheight: 300, // maximum bar length
+        // barwidth: 20, // bar thickness
+        // barspace: 2 // space between two bars
+      },
+      barchart: getDefaultBarSettings(app),
+      violin: getDefaultViolinSettings(app),
+      boxplot: getDefaultBoxplotSettings(app),
+      sampleScatter: getDefaultScatterSettings(opts)
+    },
+    mayAdjustConfig(config2, edits = {}) {
+      return mayAdjustConfig(config2, opts, edits);
+    }
+  };
+  if (config.term.term.type == "geneVariant") config.settings.barchart.colorBars = true;
+  copyMerge(config, opts);
+  Object.assign(config.controlLabels, app.vocabApi.termdbConfig.uiLabels || {});
+  return config;
+}
+var discreteByContinuousPlots = /* @__PURE__ */ new Set(["violin", "boxplot"]);
+function mayAdjustConfig(config, opts, edits = {}) {
+  if (edits.childType) {
+    if (config.childType != edits.childType) throw `action.config.childType was not applied in mass store.plot_edit()`;
+    return;
+  }
+  if (config.term?.q?.mode == "continuous" && config.term2?.q?.mode == "continuous") {
+    config.childType = "sampleScatter";
+  } else if (config.term?.term?.type == "termCollection") {
+    if (config.term.term.memberType == "categorical") {
+      config.childType = "barchart";
+    } else if (config.term.term.memberType == "numeric") {
+      if (config.childType) {
+        if (config.childType == "barchart") {
+          config.childType = "violin";
+        } else {
+        }
+      } else {
+        config.childType = "violin";
+      }
+    } else {
+      throw new Error("config.term.term.memberType not categorical or numeric");
+    }
+  } else if (config.term?.q?.mode == "continuous" || config.term2?.q?.mode == "continuous") {
+    if (!discreteByContinuousPlots.has(config.childType)) {
+      if (opts.childType && !discreteByContinuousPlots.has(opts.childType)) {
+        console.warn(
+          `ignoring summary opts.childType='${opts.childType}' since it does not support plotting discrete by continuous tw's`
+        );
+        config.childType = "violin";
+      } else {
+        config.childType = opts.childType || "violin";
+      }
+    }
+  } else {
+    config.childType = "barchart";
+  }
+}
+
+export {
+  summaryInit,
+  componentInit,
+  getPlotConfig,
+  mayAdjustConfig
+};
+//# sourceMappingURL=chunk-3T2PCWII.js.map

package/dist/chunk-4BTAI6HQ.js

@@ -0,0 +1,100 @@
+import {
+  SearchHandler,
+  fillTermWrapper,
+  table2col,
+  termsettingInit
+} from "./chunk-YWUVCXFS.js";
+
+// plots/summarizeMutationDiagnosis.ts
+async function makeChartBtnMenu(holder, chartsInstance) {
+  let dictTw;
+  {
+    const t = chartsInstance.app.vocabApi.termdbConfig.defaultTw4correlationPlot?.disease;
+    if (!t) throw "defaultTw4correlationPlot missing";
+    dictTw = structuredClone(t);
+    await fillTermWrapper(dictTw, chartsInstance.app.vocabApi);
+  }
+  const table = table2col({
+    holder: holder.append("div"),
+    margin: "0px 10px 10px 10px",
+    cellPadding: "10px"
+  });
+  {
+    const [td1, td2] = table.addRow();
+    td1.text("Mutation Variable");
+    const searchDiv = td2.append("div");
+    const geneSearchInst = new SearchHandler();
+    geneSearchInst.init({
+      holder: searchDiv,
+      app: chartsInstance.app,
+      // required to supply "opts.app.vocabApi" for the search ui
+      genomeObj: chartsInstance.app.opts.genome,
+      msg: "Hit ENTER to launch plot.",
+      callback: async (geneTw) => {
+        await fillTermWrapper(geneTw, chartsInstance.app.vocabApi);
+        launchPlot({
+          tw1: dictTw,
+          tw2: geneTw,
+          chartsInstance,
+          holder
+        });
+      }
+    });
+    searchDiv.style("padding", "0px 0px 5px 0px");
+  }
+  {
+    const [td1, td2] = table.addRow();
+    td1.text("Compare Mutations Against");
+    const pillDiv = td2.append("div"), waitDiv = td2.append("div").style("font-size", ".7em").text("LOADING ...");
+    const pill = await termsettingInit({
+      menuOptions: "{edit,replace}",
+      /** presumably this usecase let it restrict to dictionary term ui, and hide genomic queries
+      target="filter" works for gdc since in gdc ds it is overriding filter to dict
+      but is not a general fix for non-gdc ds, which Replace menu will launch genomic+dict options
+      maybe this is okay for non-gdc ds as the default dictTw is meaningful
+      */
+      usecase: { target: "filter" },
+      vocabApi: chartsInstance.app.vocabApi,
+      holder: pillDiv,
+      callback: async (tw) => {
+        waitDiv.text("LOADING ...");
+        try {
+          await pill.main(tw);
+          dictTw = tw;
+          waitDiv.text("Click to edit/replace the variable before searching gene.");
+        } catch (e) {
+          waitDiv.text("Error: " + (e.message || e));
+        }
+      }
+    });
+    try {
+      await fillTermWrapper(dictTw, chartsInstance.app.vocabApi);
+      await pill.main(dictTw);
+      waitDiv.text("Click to edit/replace the variable before searching gene.");
+    } catch (e) {
+      waitDiv.text("Error: " + (e.message || e));
+    }
+  }
+}
+function launchPlot({ tw1, tw2, chartsInstance, holder }) {
+  const chart = {
+    config: {
+      chartType: tw1?.term?.type == "survival" ? "survival" : "summary",
+      // TODO define sandbox header with gene+term name
+      term: tw1,
+      term2: tw2
+    }
+  };
+  chartsInstance.plotCreate(chart);
+  holder.selectAll("*").remove();
+  holder.append("div").style("margin", "20px").text("LOADING CHART ...");
+  setTimeout(() => {
+    holder.style("display", "none");
+  }, 1e3);
+}
+
+export {
+  makeChartBtnMenu,
+  launchPlot
+};
+//# sourceMappingURL=chunk-4BTAI6HQ.js.map