minimap2 0.2.22.0 → 0.2.24.1
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- checksums.yaml +4 -4
- data/README.md +60 -76
- data/ext/Rakefile +55 -0
- data/ext/cmappy/cmappy.c +129 -0
- data/ext/cmappy/cmappy.h +44 -0
- data/ext/minimap2/FAQ.md +46 -0
- data/ext/minimap2/LICENSE.txt +24 -0
- data/ext/minimap2/MANIFEST.in +10 -0
- data/ext/minimap2/Makefile +132 -0
- data/ext/minimap2/Makefile.simde +97 -0
- data/ext/minimap2/NEWS.md +821 -0
- data/ext/minimap2/README.md +403 -0
- data/ext/minimap2/align.c +1020 -0
- data/ext/minimap2/bseq.c +169 -0
- data/ext/minimap2/bseq.h +64 -0
- data/ext/minimap2/code_of_conduct.md +30 -0
- data/ext/minimap2/cookbook.md +243 -0
- data/ext/minimap2/esterr.c +64 -0
- data/ext/minimap2/example.c +63 -0
- data/ext/minimap2/format.c +559 -0
- data/ext/minimap2/hit.c +466 -0
- data/ext/minimap2/index.c +775 -0
- data/ext/minimap2/kalloc.c +205 -0
- data/ext/minimap2/kalloc.h +76 -0
- data/ext/minimap2/kdq.h +132 -0
- data/ext/minimap2/ketopt.h +120 -0
- data/ext/minimap2/khash.h +615 -0
- data/ext/minimap2/krmq.h +474 -0
- data/ext/minimap2/kseq.h +256 -0
- data/ext/minimap2/ksort.h +153 -0
- data/ext/minimap2/ksw2.h +184 -0
- data/ext/minimap2/ksw2_dispatch.c +96 -0
- data/ext/minimap2/ksw2_extd2_sse.c +402 -0
- data/ext/minimap2/ksw2_exts2_sse.c +416 -0
- data/ext/minimap2/ksw2_extz2_sse.c +313 -0
- data/ext/minimap2/ksw2_ll_sse.c +152 -0
- data/ext/minimap2/kthread.c +159 -0
- data/ext/minimap2/kthread.h +15 -0
- data/ext/minimap2/kvec.h +105 -0
- data/ext/minimap2/lchain.c +369 -0
- data/ext/minimap2/main.c +459 -0
- data/ext/minimap2/map.c +714 -0
- data/ext/minimap2/minimap.h +410 -0
- data/ext/minimap2/minimap2.1 +725 -0
- data/ext/minimap2/misc/README.md +179 -0
- data/ext/minimap2/misc/mmphase.js +335 -0
- data/ext/minimap2/misc/paftools.js +3149 -0
- data/ext/minimap2/misc.c +162 -0
- data/ext/minimap2/mmpriv.h +132 -0
- data/ext/minimap2/options.c +234 -0
- data/ext/minimap2/pe.c +177 -0
- data/ext/minimap2/python/README.rst +196 -0
- data/ext/minimap2/python/cmappy.h +152 -0
- data/ext/minimap2/python/cmappy.pxd +153 -0
- data/ext/minimap2/python/mappy.pyx +273 -0
- data/ext/minimap2/python/minimap2.py +39 -0
- data/ext/minimap2/sdust.c +213 -0
- data/ext/minimap2/sdust.h +25 -0
- data/ext/minimap2/seed.c +131 -0
- data/ext/minimap2/setup.py +55 -0
- data/ext/minimap2/sketch.c +143 -0
- data/ext/minimap2/splitidx.c +84 -0
- data/ext/minimap2/sse2neon/emmintrin.h +1689 -0
- data/ext/minimap2/test/MT-human.fa +278 -0
- data/ext/minimap2/test/MT-orang.fa +276 -0
- data/ext/minimap2/test/q-inv.fa +4 -0
- data/ext/minimap2/test/q2.fa +2 -0
- data/ext/minimap2/test/t-inv.fa +127 -0
- data/ext/minimap2/test/t2.fa +2 -0
- data/ext/minimap2/tex/Makefile +21 -0
- data/ext/minimap2/tex/bioinfo.cls +930 -0
- data/ext/minimap2/tex/blasr-mc.eval +17 -0
- data/ext/minimap2/tex/bowtie2-s3.sam.eval +28 -0
- data/ext/minimap2/tex/bwa-s3.sam.eval +52 -0
- data/ext/minimap2/tex/bwa.eval +55 -0
- data/ext/minimap2/tex/eval2roc.pl +33 -0
- data/ext/minimap2/tex/graphmap.eval +4 -0
- data/ext/minimap2/tex/hs38-simu.sh +10 -0
- data/ext/minimap2/tex/minialign.eval +49 -0
- data/ext/minimap2/tex/minimap2.bib +460 -0
- data/ext/minimap2/tex/minimap2.tex +724 -0
- data/ext/minimap2/tex/mm2-s3.sam.eval +62 -0
- data/ext/minimap2/tex/mm2-update.tex +240 -0
- data/ext/minimap2/tex/mm2.approx.eval +12 -0
- data/ext/minimap2/tex/mm2.eval +13 -0
- data/ext/minimap2/tex/natbib.bst +1288 -0
- data/ext/minimap2/tex/natbib.sty +803 -0
- data/ext/minimap2/tex/ngmlr.eval +38 -0
- data/ext/minimap2/tex/roc.gp +60 -0
- data/ext/minimap2/tex/snap-s3.sam.eval +62 -0
- data/ext/minimap2.patch +19 -0
- data/lib/minimap2/aligner.rb +4 -4
- data/lib/minimap2/alignment.rb +11 -11
- data/lib/minimap2/ffi/constants.rb +20 -16
- data/lib/minimap2/ffi/functions.rb +5 -0
- data/lib/minimap2/ffi.rb +4 -5
- data/lib/minimap2/version.rb +2 -2
- data/lib/minimap2.rb +51 -15
- metadata +97 -79
- data/lib/minimap2/ffi_helper.rb +0 -53
- data/vendor/libminimap2.so +0 -0
@@ -0,0 +1,17 @@
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#!/usr/bin/perl
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use strict;
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use warnings;
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use Getopt::Std;
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my %opts = (n=>33088, s=>100);
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getopts('n:', \%opts);
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my $pseudo = .5;
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my $tot = $pseudo;
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my $err = $pseudo;
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my $tot_last_out = -$opts{s};
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my $state = 0;
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my $mapq = 0;
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while (<>) {
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chomp;
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if (/^Q\t(\d+)\t(\d+)\t(\d+)/) {
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$tot += $2;
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$err += $3;
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if ($tot - $tot_last_out >= $opts{s}) {
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print join("\t", $1, $err/$tot, $tot / $opts{n}), "\n";
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$tot_last_out = $tot;
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$state = 0;
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} else {
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$state = 1;
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$mapq = $1;
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}
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}
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}
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if ($state) {
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print join("\t", $mapq, $err/$tot, $tot / $opts{n}), "\n";
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}
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./pbsim --prefix pb-1 --depth 0.1 --sample-fastq m131017_060208_42213_c100579642550000001823095604021496_s1_p0.1.subreads.fastq --length-min 1000 --length-max 30000 --seed 11 hs38.fa
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bin/mason_variator -ir hs38.fa -s 1 -ov hs38-s1.vcf --snp-rate 1e-3 --small-indel-rate 2e-4 --sv-indel-rate 0 --sv-inversion-rate 0 --sv-translocation-rate 0 --sv-duplication-rate 0 --max-small-indel-size 10
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bin/mason_simulator -ir hs38.fa -iv hs38-s1.vcf -n 1000000 --seed 1 -o s1_1.fq -or s1_2.fq -oa s1.sam --illumina-prob-mismatch-scale 2.5
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bin/mason_variator -ir hs38.fa -s 2 -ov hs38-s2.vcf --snp-rate 1e-3 --small-indel-rate 2e-4 --sv-indel-rate 0 --sv-inversion-rate 0 --sv-translocation-rate 0 --sv-duplication-rate 0 --max-small-indel-size 10
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bin/mason_simulator -ir hs38.fa -iv hs38-s2.vcf -n 1000000 --seed 2 -o mason-s2_1.fq -or mason-s2_2.fq -oa mason-s2.sam --illumina-prob-mismatch-scale 2.5 --illumina-read-length 150
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bin/mason_variator -ir hs38.fa -s 3 -ov hs38-s3.vcf --snp-rate 1e-3 --small-indel-rate 2e-4 --sv-indel-rate 0 --sv-inversion-rate 0 --sv-translocation-rate 0 --sv-duplication-rate 0 --max-small-indel-size 10
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bin/mason_simulator -ir hs38.fa -iv hs38-s3.vcf -n 10000000 --seed 3 -o mason-s3_1.fq -or mason-s3_2.fq -oa mason-s3.sam --illumina-prob-mismatch-scale 2.5 --illumina-read-length 150
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Q 60 32070 190 0.005924540
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Q 59 62 2 0.005975352
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Q 58 37 5 0.006123908
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Q 57 40 7 0.006333633
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Q 56 39 6 0.006512032
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Q 55 32 2 0.006567534
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Q 53 33 4 0.006735255
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Q 51 48 3 0.006871264
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Q 50 34 2 0.006925634
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Q 49 32 3 0.007011070
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Q 48 35 2 0.007064967
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Q 47 36 4 0.007179896
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Q 46 23 1 0.007205495
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Q 44 17 3 0.007318716
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Q 41 25 4 0.007638486
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|
26
|
+
Q 34 20 3 0.008156805
|
27
|
+
Q 33 11 1 0.008184501
|
28
|
+
Q 32 15 3 0.008272003
|
29
|
+
Q 31 25 1 0.008296107
|
30
|
+
Q 29 8 1 0.008324472
|
31
|
+
Q 28 7 2 0.008383452
|
32
|
+
Q 27 9 2 0.008441894
|
33
|
+
Q 26 30 2 0.008494888
|
34
|
+
Q 23 2 1 0.008524710
|
35
|
+
Q 22 11 3 0.008612846
|
36
|
+
Q 20 23 3 0.008697760
|
37
|
+
Q 19 6 1 0.008726479
|
38
|
+
Q 18 8 1 0.008754658
|
39
|
+
Q 16 6 1 0.008783354
|
40
|
+
Q 13 2 1 0.008813108
|
41
|
+
Q 12 4 2 0.008872604
|
42
|
+
Q 11 7 2 0.008931275
|
43
|
+
Q 10 4 3 0.009021009
|
44
|
+
Q 9 6 4 0.009140436
|
45
|
+
Q 8 6 3 0.009229559
|
46
|
+
Q 7 5 1 0.009258419
|
47
|
+
Q 6 8 3 0.009346925
|
48
|
+
Q 4 8 5 0.009495872
|
49
|
+
Q 3 17 8 0.009732801
|