bio 1.0.0 → 1.1.0
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- data/bin/bioruby +14 -122
- data/bin/br_biofetch.rb +2 -2
- data/bin/br_bioflat.rb +2 -2
- data/bin/br_biogetseq.rb +2 -2
- data/bin/br_pmfetch.rb +3 -3
- data/doc/Changes-0.7.rd +77 -0
- data/doc/KEGG_API.rd +523 -232
- data/doc/KEGG_API.rd.ja +529 -207
- data/doc/Tutorial.rd +48 -11
- data/lib/bio.rb +59 -6
- data/lib/bio/alignment.rb +713 -103
- data/lib/bio/appl/bl2seq/report.rb +2 -18
- data/lib/bio/appl/blast.rb +108 -91
- data/lib/bio/appl/blast/format0.rb +33 -18
- data/lib/bio/appl/blast/format8.rb +6 -20
- data/lib/bio/appl/blast/report.rb +293 -429
- data/lib/bio/appl/blast/rexml.rb +8 -22
- data/lib/bio/appl/blast/wublast.rb +21 -12
- data/lib/bio/appl/blast/xmlparser.rb +180 -183
- data/lib/bio/appl/blat/report.rb +127 -30
- data/lib/bio/appl/clustalw.rb +87 -59
- data/lib/bio/appl/clustalw/report.rb +20 -22
- data/lib/bio/appl/emboss.rb +113 -20
- data/lib/bio/appl/fasta.rb +173 -198
- data/lib/bio/appl/fasta/format10.rb +244 -347
- data/lib/bio/appl/gcg/msf.rb +212 -0
- data/lib/bio/appl/gcg/seq.rb +195 -0
- data/lib/bio/appl/genscan/report.rb +5 -23
- data/lib/bio/appl/hmmer.rb +8 -45
- data/lib/bio/appl/hmmer/report.rb +2 -20
- data/lib/bio/appl/iprscan/report.rb +374 -0
- data/lib/bio/appl/mafft.rb +87 -50
- data/lib/bio/appl/mafft/report.rb +151 -44
- data/lib/bio/appl/muscle.rb +52 -0
- data/lib/bio/appl/phylip/alignment.rb +129 -0
- data/lib/bio/appl/phylip/distance_matrix.rb +96 -0
- data/lib/bio/appl/probcons.rb +41 -0
- data/lib/bio/appl/psort.rb +89 -96
- data/lib/bio/appl/psort/report.rb +6 -22
- data/lib/bio/appl/pts1.rb +263 -0
- data/lib/bio/appl/sim4.rb +26 -36
- data/lib/bio/appl/sim4/report.rb +2 -18
- data/lib/bio/appl/sosui/report.rb +5 -20
- data/lib/bio/appl/spidey/report.rb +2 -2
- data/lib/bio/appl/targetp/report.rb +4 -20
- data/lib/bio/appl/tcoffee.rb +55 -0
- data/lib/bio/appl/tmhmm/report.rb +4 -20
- data/lib/bio/command.rb +235 -64
- data/lib/bio/data/aa.rb +21 -26
- data/lib/bio/data/codontable.rb +2 -20
- data/lib/bio/data/na.rb +19 -4
- data/lib/bio/db.rb +27 -12
- data/lib/bio/db/aaindex.rb +2 -20
- data/lib/bio/db/embl/common.rb +4 -21
- data/lib/bio/db/embl/embl.rb +33 -85
- data/lib/bio/db/embl/sptr.rb +612 -302
- data/lib/bio/db/embl/swissprot.rb +10 -29
- data/lib/bio/db/embl/trembl.rb +10 -29
- data/lib/bio/db/embl/uniprot.rb +10 -29
- data/lib/bio/db/fantom.rb +15 -20
- data/lib/bio/db/fasta.rb +3 -3
- data/lib/bio/db/genbank/common.rb +37 -46
- data/lib/bio/db/genbank/ddbj.rb +6 -18
- data/lib/bio/db/genbank/genbank.rb +47 -186
- data/lib/bio/db/genbank/genpept.rb +4 -17
- data/lib/bio/db/genbank/refseq.rb +4 -17
- data/lib/bio/db/gff.rb +103 -35
- data/lib/bio/db/go.rb +4 -20
- data/lib/bio/db/kegg/brite.rb +26 -36
- data/lib/bio/db/kegg/compound.rb +81 -85
- data/lib/bio/db/kegg/drug.rb +98 -0
- data/lib/bio/db/kegg/enzyme.rb +133 -110
- data/lib/bio/db/kegg/expression.rb +2 -20
- data/lib/bio/db/kegg/genes.rb +208 -238
- data/lib/bio/db/kegg/genome.rb +164 -285
- data/lib/bio/db/kegg/glycan.rb +114 -157
- data/lib/bio/db/kegg/keggtab.rb +242 -303
- data/lib/bio/db/kegg/kgml.rb +117 -160
- data/lib/bio/db/kegg/orthology.rb +112 -0
- data/lib/bio/db/kegg/reaction.rb +54 -69
- data/lib/bio/db/kegg/taxonomy.rb +331 -0
- data/lib/bio/db/lasergene.rb +209 -0
- data/lib/bio/db/litdb.rb +3 -27
- data/lib/bio/db/medline.rb +228 -249
- data/lib/bio/db/nbrf.rb +3 -3
- data/lib/bio/db/newick.rb +510 -0
- data/lib/bio/db/nexus.rb +1854 -0
- data/lib/bio/db/pdb.rb +5 -17
- data/lib/bio/db/pdb/atom.rb +2 -18
- data/lib/bio/db/pdb/chain.rb +2 -18
- data/lib/bio/db/pdb/chemicalcomponent.rb +2 -18
- data/lib/bio/db/pdb/model.rb +2 -18
- data/lib/bio/db/pdb/pdb.rb +73 -34
- data/lib/bio/db/pdb/residue.rb +4 -20
- data/lib/bio/db/pdb/utils.rb +2 -18
- data/lib/bio/db/prosite.rb +403 -422
- data/lib/bio/db/rebase.rb +84 -40
- data/lib/bio/db/soft.rb +404 -0
- data/lib/bio/db/transfac.rb +5 -17
- data/lib/bio/feature.rb +106 -52
- data/lib/bio/io/das.rb +32 -42
- data/lib/bio/io/dbget.rb +2 -20
- data/lib/bio/io/ddbjxml.rb +77 -138
- data/lib/bio/io/ebisoap.rb +158 -0
- data/lib/bio/io/ensembl.rb +229 -0
- data/lib/bio/io/fastacmd.rb +89 -82
- data/lib/bio/io/fetch.rb +163 -96
- data/lib/bio/io/flatfile.rb +170 -73
- data/lib/bio/io/flatfile/bdb.rb +3 -16
- data/lib/bio/io/flatfile/index.rb +2 -2
- data/lib/bio/io/flatfile/indexer.rb +3 -2
- data/lib/bio/io/higet.rb +12 -31
- data/lib/bio/io/keggapi.rb +210 -269
- data/lib/bio/io/ncbisoap.rb +155 -0
- data/lib/bio/io/pubmed.rb +169 -147
- data/lib/bio/io/registry.rb +4 -20
- data/lib/bio/io/soapwsdl.rb +43 -38
- data/lib/bio/io/sql.rb +242 -305
- data/lib/bio/location.rb +407 -285
- data/lib/bio/map.rb +410 -0
- data/lib/bio/pathway.rb +558 -695
- data/lib/bio/reference.rb +272 -75
- data/lib/bio/sequence.rb +255 -13
- data/lib/bio/sequence/aa.rb +71 -10
- data/lib/bio/sequence/common.rb +187 -33
- data/lib/bio/sequence/compat.rb +59 -4
- data/lib/bio/sequence/format.rb +54 -7
- data/lib/bio/sequence/generic.rb +3 -3
- data/lib/bio/sequence/na.rb +328 -26
- data/lib/bio/shell.rb +11 -4
- data/lib/bio/shell/core.rb +221 -160
- data/lib/bio/shell/demo.rb +18 -15
- data/lib/bio/shell/interface.rb +14 -12
- data/lib/bio/shell/irb.rb +95 -0
- data/lib/bio/shell/object.rb +45 -26
- data/lib/bio/shell/plugin/blast.rb +42 -0
- data/lib/bio/shell/plugin/codon.rb +22 -14
- data/lib/bio/shell/plugin/das.rb +58 -0
- data/lib/bio/shell/plugin/emboss.rb +2 -2
- data/lib/bio/shell/plugin/entry.rb +22 -11
- data/lib/bio/shell/plugin/flatfile.rb +2 -2
- data/lib/bio/shell/plugin/keggapi.rb +13 -6
- data/lib/bio/shell/plugin/midi.rb +4 -4
- data/lib/bio/shell/plugin/obda.rb +2 -2
- data/lib/bio/shell/plugin/psort.rb +56 -0
- data/lib/bio/shell/plugin/seq.rb +35 -8
- data/lib/bio/shell/plugin/soap.rb +87 -0
- data/lib/bio/shell/rails/vendor/plugins/generators/bioruby/bioruby_generator.rb +29 -0
- data/lib/bio/shell/rails/vendor/plugins/generators/bioruby/templates/_classes.rhtml +4 -0
- data/lib/bio/shell/rails/vendor/plugins/generators/bioruby/templates/_log.rhtml +27 -0
- data/lib/bio/shell/rails/vendor/plugins/generators/bioruby/templates/_methods.rhtml +11 -0
- data/lib/bio/shell/rails/vendor/plugins/generators/bioruby/templates/_modules.rhtml +4 -0
- data/lib/bio/shell/rails/vendor/plugins/generators/bioruby/templates/_variables.rhtml +7 -0
- data/lib/bio/shell/rails/vendor/plugins/generators/bioruby/templates/bioruby-bg.gif +0 -0
- data/lib/bio/shell/rails/vendor/plugins/generators/bioruby/templates/bioruby-console.png +0 -0
- data/lib/bio/shell/rails/{public/images/icon.png → vendor/plugins/generators/bioruby/templates/bioruby-gem.png} +0 -0
- data/lib/bio/shell/rails/vendor/plugins/generators/bioruby/templates/bioruby-link.gif +0 -0
- data/lib/bio/shell/rails/vendor/plugins/generators/bioruby/templates/bioruby.css +369 -0
- data/lib/bio/shell/rails/vendor/plugins/generators/bioruby/templates/bioruby.rhtml +47 -0
- data/lib/bio/shell/rails/vendor/plugins/generators/bioruby/templates/bioruby_controller.rb +144 -0
- data/lib/bio/shell/rails/vendor/plugins/generators/bioruby/templates/bioruby_helper.rb +47 -0
- data/lib/bio/shell/rails/vendor/plugins/generators/bioruby/templates/commands.rhtml +8 -0
- data/lib/bio/shell/rails/vendor/plugins/generators/bioruby/templates/history.rhtml +10 -0
- data/lib/bio/shell/rails/vendor/plugins/generators/bioruby/templates/index.rhtml +22 -0
- data/lib/bio/shell/script.rb +25 -0
- data/lib/bio/shell/setup.rb +109 -0
- data/lib/bio/shell/web.rb +70 -58
- data/lib/bio/tree.rb +850 -0
- data/lib/bio/util/color_scheme.rb +84 -107
- data/lib/bio/util/color_scheme/buried.rb +5 -24
- data/lib/bio/util/color_scheme/helix.rb +5 -24
- data/lib/bio/util/color_scheme/hydropathy.rb +5 -24
- data/lib/bio/util/color_scheme/nucleotide.rb +5 -24
- data/lib/bio/util/color_scheme/strand.rb +5 -24
- data/lib/bio/util/color_scheme/taylor.rb +5 -24
- data/lib/bio/util/color_scheme/turn.rb +5 -24
- data/lib/bio/util/color_scheme/zappo.rb +5 -24
- data/lib/bio/util/contingency_table.rb +70 -43
- data/lib/bio/util/restriction_enzyme.rb +228 -0
- data/lib/bio/util/restriction_enzyme/analysis.rb +249 -0
- data/lib/bio/util/restriction_enzyme/analysis_basic.rb +217 -0
- data/lib/bio/util/restriction_enzyme/cut_symbol.rb +107 -0
- data/lib/bio/util/restriction_enzyme/double_stranded.rb +321 -0
- data/lib/bio/util/restriction_enzyme/double_stranded/aligned_strands.rb +130 -0
- data/lib/bio/util/restriction_enzyme/double_stranded/cut_location_pair.rb +103 -0
- data/lib/bio/util/restriction_enzyme/double_stranded/cut_location_pair_in_enzyme_notation.rb +38 -0
- data/lib/bio/util/restriction_enzyme/double_stranded/cut_locations.rb +76 -0
- data/lib/bio/util/restriction_enzyme/double_stranded/cut_locations_in_enzyme_notation.rb +107 -0
- data/lib/bio/util/restriction_enzyme/enzymes.yaml +7061 -0
- data/lib/bio/util/restriction_enzyme/range/cut_range.rb +24 -0
- data/lib/bio/util/restriction_enzyme/range/cut_ranges.rb +47 -0
- data/lib/bio/util/restriction_enzyme/range/horizontal_cut_range.rb +67 -0
- data/lib/bio/util/restriction_enzyme/range/sequence_range.rb +257 -0
- data/lib/bio/util/restriction_enzyme/range/sequence_range/calculated_cuts.rb +242 -0
- data/lib/bio/util/restriction_enzyme/range/sequence_range/fragment.rb +51 -0
- data/lib/bio/util/restriction_enzyme/range/sequence_range/fragments.rb +41 -0
- data/lib/bio/util/restriction_enzyme/range/vertical_cut_range.rb +77 -0
- data/lib/bio/util/restriction_enzyme/single_strand.rb +199 -0
- data/lib/bio/util/restriction_enzyme/single_strand/cut_locations_in_enzyme_notation.rb +135 -0
- data/lib/bio/util/restriction_enzyme/single_strand_complement.rb +23 -0
- data/lib/bio/util/restriction_enzyme/string_formatting.rb +111 -0
- data/lib/bio/util/sirna.rb +4 -22
- data/sample/color_scheme_na.rb +4 -12
- data/sample/enzymes.rb +78 -0
- data/sample/goslim.rb +5 -13
- data/sample/psortplot_html.rb +4 -12
- data/test/data/blast/2.2.15.blastp.m7 +876 -0
- data/test/data/embl/AB090716.embl.rel89 +63 -0
- data/test/data/fasta/example1.txt +75 -0
- data/test/data/fasta/example2.txt +21 -0
- data/test/data/iprscan/merged.raw +32 -0
- data/test/data/iprscan/merged.txt +74 -0
- data/test/data/soft/GDS100_partial.soft +92 -0
- data/test/data/soft/GSE3457_family_partial.soft +874 -0
- data/test/functional/bio/io/test_ensembl.rb +103 -0
- data/test/functional/bio/io/test_soapwsdl.rb +5 -17
- data/test/unit/bio/appl/bl2seq/test_report.rb +2 -2
- data/test/unit/bio/appl/blast/test_report.rb +3 -16
- data/test/unit/bio/appl/blast/test_xmlparser.rb +4 -16
- data/test/unit/bio/appl/genscan/test_report.rb +3 -16
- data/test/unit/bio/appl/hmmer/test_report.rb +3 -16
- data/test/unit/bio/appl/iprscan/test_report.rb +338 -0
- data/test/unit/bio/appl/mafft/test_report.rb +63 -0
- data/test/unit/bio/appl/sosui/test_report.rb +3 -16
- data/test/unit/bio/appl/targetp/test_report.rb +3 -16
- data/test/unit/bio/appl/test_blast.rb +3 -16
- data/test/unit/bio/appl/test_fasta.rb +4 -16
- data/test/unit/bio/appl/test_pts1.rb +140 -0
- data/test/unit/bio/appl/tmhmm/test_report.rb +3 -16
- data/test/unit/bio/data/test_aa.rb +4 -17
- data/test/unit/bio/data/test_codontable.rb +3 -16
- data/test/unit/bio/data/test_na.rb +3 -3
- data/test/unit/bio/db/embl/test_common.rb +3 -16
- data/test/unit/bio/db/embl/test_embl.rb +3 -16
- data/test/unit/bio/db/embl/test_embl_rel89.rb +219 -0
- data/test/unit/bio/db/embl/test_sptr.rb +1548 -41
- data/test/unit/bio/db/embl/test_uniprot.rb +3 -16
- data/test/unit/bio/db/kegg/test_genes.rb +3 -16
- data/test/unit/bio/db/pdb/test_pdb.rb +7 -24
- data/test/unit/bio/db/test_aaindex.rb +2 -2
- data/test/unit/bio/db/test_fasta.rb +3 -16
- data/test/unit/bio/db/test_gff.rb +3 -16
- data/test/unit/bio/db/test_lasergene.rb +95 -0
- data/test/unit/bio/db/test_newick.rb +56 -0
- data/test/unit/bio/db/test_nexus.rb +360 -0
- data/test/unit/bio/db/test_prosite.rb +5 -18
- data/test/unit/bio/db/test_rebase.rb +11 -25
- data/test/unit/bio/db/test_soft.rb +138 -0
- data/test/unit/bio/io/test_ddbjxml.rb +5 -17
- data/test/unit/bio/io/test_ensembl.rb +109 -0
- data/test/unit/bio/io/test_fastacmd.rb +3 -16
- data/test/unit/bio/io/test_flatfile.rb +237 -0
- data/test/unit/bio/io/test_soapwsdl.rb +4 -17
- data/test/unit/bio/sequence/test_aa.rb +3 -3
- data/test/unit/bio/sequence/test_common.rb +3 -16
- data/test/unit/bio/sequence/test_compat.rb +3 -16
- data/test/unit/bio/sequence/test_na.rb +29 -3
- data/test/unit/bio/shell/plugin/test_seq.rb +8 -8
- data/test/unit/bio/test_alignment.rb +16 -27
- data/test/unit/bio/test_command.rb +242 -25
- data/test/unit/bio/test_db.rb +3 -16
- data/test/unit/bio/test_feature.rb +4 -16
- data/test/unit/bio/test_location.rb +4 -16
- data/test/unit/bio/test_map.rb +230 -0
- data/test/unit/bio/test_pathway.rb +4 -16
- data/test/unit/bio/test_reference.rb +2 -2
- data/test/unit/bio/test_sequence.rb +7 -19
- data/test/unit/bio/test_shell.rb +3 -16
- data/test/unit/bio/test_tree.rb +593 -0
- data/test/unit/bio/util/restriction_enzyme/analysis/test_calculated_cuts.rb +299 -0
- data/test/unit/bio/util/restriction_enzyme/analysis/test_cut_ranges.rb +103 -0
- data/test/unit/bio/util/restriction_enzyme/analysis/test_sequence_range.rb +240 -0
- data/test/unit/bio/util/restriction_enzyme/double_stranded/test_aligned_strands.rb +100 -0
- data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_location_pair.rb +75 -0
- data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_location_pair_in_enzyme_notation.rb +73 -0
- data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_locations.rb +53 -0
- data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_locations_in_enzyme_notation.rb +104 -0
- data/test/unit/bio/util/restriction_enzyme/single_strand/test_cut_locations_in_enzyme_notation.rb +83 -0
- data/test/unit/bio/util/restriction_enzyme/test_analysis.rb +246 -0
- data/test/unit/bio/util/restriction_enzyme/test_cut_symbol.rb +44 -0
- data/test/unit/bio/util/restriction_enzyme/test_double_stranded.rb +115 -0
- data/test/unit/bio/util/restriction_enzyme/test_single_strand.rb +147 -0
- data/test/unit/bio/util/restriction_enzyme/test_single_strand_complement.rb +147 -0
- data/test/unit/bio/util/restriction_enzyme/test_string_formatting.rb +60 -0
- data/test/unit/bio/util/test_color_scheme.rb +6 -18
- data/test/unit/bio/util/test_contingency_table.rb +6 -18
- data/test/unit/bio/util/test_restriction_enzyme.rb +42 -0
- data/test/unit/bio/util/test_sirna.rb +3 -16
- metadata +228 -169
- data/doc/BioRuby.rd.ja +0 -225
- data/doc/Design.rd.ja +0 -341
- data/doc/TODO.rd.ja +0 -138
- data/lib/bio/appl/fasta/format6.rb +0 -37
- data/lib/bio/db/kegg/cell.rb +0 -88
- data/lib/bio/db/kegg/ko.rb +0 -178
- data/lib/bio/shell/rails/Rakefile +0 -10
- data/lib/bio/shell/rails/app/controllers/application.rb +0 -4
- data/lib/bio/shell/rails/app/controllers/shell_controller.rb +0 -94
- data/lib/bio/shell/rails/app/helpers/application_helper.rb +0 -3
- data/lib/bio/shell/rails/app/models/shell_connection.rb +0 -30
- data/lib/bio/shell/rails/app/views/layouts/shell.rhtml +0 -37
- data/lib/bio/shell/rails/app/views/shell/history.rhtml +0 -5
- data/lib/bio/shell/rails/app/views/shell/index.rhtml +0 -2
- data/lib/bio/shell/rails/app/views/shell/show.rhtml +0 -13
- data/lib/bio/shell/rails/config/boot.rb +0 -19
- data/lib/bio/shell/rails/config/database.yml +0 -85
- data/lib/bio/shell/rails/config/environment.rb +0 -53
- data/lib/bio/shell/rails/config/environments/development.rb +0 -19
- data/lib/bio/shell/rails/config/environments/production.rb +0 -19
- data/lib/bio/shell/rails/config/environments/test.rb +0 -19
- data/lib/bio/shell/rails/config/routes.rb +0 -19
- data/lib/bio/shell/rails/doc/README_FOR_APP +0 -2
- data/lib/bio/shell/rails/public/404.html +0 -8
- data/lib/bio/shell/rails/public/500.html +0 -8
- data/lib/bio/shell/rails/public/dispatch.cgi +0 -10
- data/lib/bio/shell/rails/public/dispatch.fcgi +0 -24
- data/lib/bio/shell/rails/public/dispatch.rb +0 -10
- data/lib/bio/shell/rails/public/favicon.ico +0 -0
- data/lib/bio/shell/rails/public/images/rails.png +0 -0
- data/lib/bio/shell/rails/public/index.html +0 -277
- data/lib/bio/shell/rails/public/javascripts/controls.js +0 -750
- data/lib/bio/shell/rails/public/javascripts/dragdrop.js +0 -584
- data/lib/bio/shell/rails/public/javascripts/effects.js +0 -854
- data/lib/bio/shell/rails/public/javascripts/prototype.js +0 -1785
- data/lib/bio/shell/rails/public/robots.txt +0 -1
- data/lib/bio/shell/rails/public/stylesheets/main.css +0 -187
- data/lib/bio/shell/rails/script/about +0 -3
- data/lib/bio/shell/rails/script/breakpointer +0 -3
- data/lib/bio/shell/rails/script/console +0 -3
- data/lib/bio/shell/rails/script/destroy +0 -3
- data/lib/bio/shell/rails/script/generate +0 -3
- data/lib/bio/shell/rails/script/performance/benchmarker +0 -3
- data/lib/bio/shell/rails/script/performance/profiler +0 -3
- data/lib/bio/shell/rails/script/plugin +0 -3
- data/lib/bio/shell/rails/script/process/reaper +0 -3
- data/lib/bio/shell/rails/script/process/spawner +0 -3
- data/lib/bio/shell/rails/script/process/spinner +0 -3
- data/lib/bio/shell/rails/script/runner +0 -3
- data/lib/bio/shell/rails/script/server +0 -42
- data/lib/bio/shell/rails/test/test_helper.rb +0 -28
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# = bio/appl/gcg/msf.rb - GCG multiple sequence alignment (.msf) parser class
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# Copyright:: Copyright (C) 2003, 2006
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# Naohisa Goto <ng@bioruby.org>
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# License:: The Ruby License
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# $Id: msf.rb,v 1.2 2007/04/05 23:35:39 trevor Exp $
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# = About Bio::GCG::Msf
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# Please refer document of Bio::GCG::Msf.
|
13
|
+
#
|
14
|
+
|
15
|
+
#---
|
16
|
+
# (depends on autoload)
|
17
|
+
#require 'bio/appl/gcg/seq'
|
18
|
+
#+++
|
19
|
+
|
20
|
+
module Bio
|
21
|
+
module GCG
|
22
|
+
|
23
|
+
# The msf is a multiple sequence alignment format developed by Wisconsin.
|
24
|
+
# Bio::GCG::Msf is a msf format parser.
|
25
|
+
class Msf #< DB
|
26
|
+
|
27
|
+
# delimiter used by Bio::FlatFile
|
28
|
+
DELIMITER = RS = nil
|
29
|
+
|
30
|
+
# Creates a new Msf object.
|
31
|
+
def initialize(str)
|
32
|
+
str = str.sub(/\A[\r\n]+/, '')
|
33
|
+
if /^\!\![A-Z]+\_MULTIPLE\_ALIGNMNENT/ =~ str[/.*/] then
|
34
|
+
@heading = str[/.*/] # '!!NA_MULTIPLE_ALIGNMENT 1.0' or like this
|
35
|
+
str.sub!(/.*/, '')
|
36
|
+
end
|
37
|
+
str.sub!(/.*\.\.$/m, '')
|
38
|
+
@description = $&.to_s.sub(/^.*\.\.$/, '').to_s
|
39
|
+
d = $&.to_s
|
40
|
+
if m = /(.+)\s+MSF\:\s+(\d+)\s+Type\:\s+(\w)\s+(.+)\s+(Comp)?Check\:\s+(\d+)/.match(d) then
|
41
|
+
@entry_id = m[1].to_s.strip
|
42
|
+
@length = (m[2] ? m[2].to_i : nil)
|
43
|
+
@seq_type = m[3]
|
44
|
+
@date = m[4].to_s.strip
|
45
|
+
@checksum = (m[6] ? m[6].to_i : nil)
|
46
|
+
end
|
47
|
+
|
48
|
+
str.sub!(/.*\/\/$/m, '')
|
49
|
+
a = $&.to_s.split(/^/)
|
50
|
+
@seq_info = []
|
51
|
+
a.each do |x|
|
52
|
+
if /Name\: / =~ x then
|
53
|
+
s = {}
|
54
|
+
x.scan(/(\S+)\: +(\S*)/) { |y| s[$1] = $2 }
|
55
|
+
@seq_info << s
|
56
|
+
end
|
57
|
+
end
|
58
|
+
|
59
|
+
@data = str
|
60
|
+
@description.sub!(/\A(\r\n|\r|\n)/, '')
|
61
|
+
@align = nil
|
62
|
+
end
|
63
|
+
|
64
|
+
# description
|
65
|
+
attr_reader :description
|
66
|
+
|
67
|
+
# ID of the alignment
|
68
|
+
attr_reader :entry_id
|
69
|
+
|
70
|
+
# alignment length
|
71
|
+
attr_reader :length
|
72
|
+
|
73
|
+
# sequence type ("N" for DNA/RNA or "P" for protein)
|
74
|
+
attr_reader :seq_type
|
75
|
+
|
76
|
+
# date
|
77
|
+
attr_reader :date
|
78
|
+
|
79
|
+
# checksum
|
80
|
+
attr_reader :checksum
|
81
|
+
|
82
|
+
# heading
|
83
|
+
# ('!!NA_MULTIPLE_ALIGNMENT 1.0' or whatever like this)
|
84
|
+
attr_reader :heading
|
85
|
+
|
86
|
+
#---
|
87
|
+
## data (internally used, will be obsoleted)
|
88
|
+
#attr_reader :data
|
89
|
+
#
|
90
|
+
## seq. info. (internally used, will be obsoleted)
|
91
|
+
#attr_reader :seq_info
|
92
|
+
#+++
|
93
|
+
|
94
|
+
# symbol comparison table
|
95
|
+
def symbol_comparison_table
|
96
|
+
unless defined?(@symbol_comparison_table)
|
97
|
+
/Symbol comparison table\: +(\S+)/ =~ @description
|
98
|
+
@symbol_comparison_table = $1
|
99
|
+
end
|
100
|
+
@symbol_comparison_table
|
101
|
+
end
|
102
|
+
|
103
|
+
# gap weight
|
104
|
+
def gap_weight
|
105
|
+
unless defined?(@gap_weight)
|
106
|
+
/GapWeight\: +(\S+)/ =~ @description
|
107
|
+
@gap_weight = $1
|
108
|
+
end
|
109
|
+
@gap_weight
|
110
|
+
end
|
111
|
+
|
112
|
+
# gap length weight
|
113
|
+
def gap_length_weight
|
114
|
+
unless defined?(@gap_length_weight)
|
115
|
+
/GapLengthWeight\: +(\S+)/ =~ @description
|
116
|
+
@gap_length_weight = $1
|
117
|
+
end
|
118
|
+
@gap_length_weight
|
119
|
+
end
|
120
|
+
|
121
|
+
# CompCheck field
|
122
|
+
def compcheck
|
123
|
+
unless defined?(@compcheck)
|
124
|
+
if /CompCheck\: +(\d+)/ =~ @description then
|
125
|
+
@compcheck = $1.to_i
|
126
|
+
else
|
127
|
+
@compcheck = nil
|
128
|
+
end
|
129
|
+
end
|
130
|
+
@compcheck
|
131
|
+
end
|
132
|
+
|
133
|
+
# parsing
|
134
|
+
def do_parse
|
135
|
+
return if @align
|
136
|
+
a = @data.strip.split(/\n\n/)
|
137
|
+
@seq_data = Array.new(@seq_info.size)
|
138
|
+
@seq_data.collect! { |x| Array.new }
|
139
|
+
a.each do |x|
|
140
|
+
b = x.split(/\n/)
|
141
|
+
nw = 0
|
142
|
+
if b.size > @seq_info.size then
|
143
|
+
if /^ +/ =~ b.shift.to_s
|
144
|
+
nw = $&.to_s.length
|
145
|
+
end
|
146
|
+
end
|
147
|
+
if nw > 0 then
|
148
|
+
b.each_with_index { |y, i| y[0, nw] = ''; @seq_data[i] << y }
|
149
|
+
else
|
150
|
+
b.each_with_index { |y, i|
|
151
|
+
@seq_data[i] << y.strip.split(/ +/, 2)[1].to_s
|
152
|
+
}
|
153
|
+
end
|
154
|
+
end
|
155
|
+
|
156
|
+
case seq_type
|
157
|
+
when 'P', 'p'
|
158
|
+
k = Bio::Sequence::AA
|
159
|
+
when 'N', 'n'
|
160
|
+
k = Bio::Sequence::NA
|
161
|
+
else
|
162
|
+
k = Bio::Sequence::Generic
|
163
|
+
end
|
164
|
+
@seq_data.collect! do |x|
|
165
|
+
y = x.join('')
|
166
|
+
y.gsub!(/[\s\d]+/, '')
|
167
|
+
k.new(y)
|
168
|
+
end
|
169
|
+
|
170
|
+
aln = Bio::Alignment.new
|
171
|
+
@seq_data.each_with_index do |x, i|
|
172
|
+
aln.store(@seq_info[i]['Name'], x)
|
173
|
+
end
|
174
|
+
@align = aln
|
175
|
+
end
|
176
|
+
private :do_parse
|
177
|
+
|
178
|
+
# returns Bio::Alignment object.
|
179
|
+
def alignment
|
180
|
+
do_parse
|
181
|
+
@align
|
182
|
+
end
|
183
|
+
|
184
|
+
# gets seq data (used internally) (will be obsoleted)
|
185
|
+
def seq_data
|
186
|
+
do_parse
|
187
|
+
@seq_data
|
188
|
+
end
|
189
|
+
|
190
|
+
# validates checksum
|
191
|
+
def validate_checksum
|
192
|
+
do_parse
|
193
|
+
valid = true
|
194
|
+
total = 0
|
195
|
+
@seq_data.each_with_index do |x, i|
|
196
|
+
sum = Bio::GCG::Seq.calc_checksum(x)
|
197
|
+
if sum != @seq_info[i]['Check'].to_i
|
198
|
+
valid = false
|
199
|
+
break
|
200
|
+
end
|
201
|
+
total += sum
|
202
|
+
end
|
203
|
+
return false unless valid
|
204
|
+
if @checksum != 0 # "Check:" field of BioPerl is always 0
|
205
|
+
valid = ((total % 10000) == @checksum)
|
206
|
+
end
|
207
|
+
valid
|
208
|
+
end
|
209
|
+
|
210
|
+
end #class Msf
|
211
|
+
end #module GCG
|
212
|
+
end # module Bio
|
@@ -0,0 +1,195 @@
|
|
1
|
+
#
|
2
|
+
# = bio/appl/gcg/seq.rb - GCG sequence file format class (.seq/.pep file)
|
3
|
+
#
|
4
|
+
# Copyright:: Copyright (C) 2003, 2006
|
5
|
+
# Naohisa Goto <ng@bioruby.org>
|
6
|
+
# License:: The Ruby License
|
7
|
+
#
|
8
|
+
# $Id: seq.rb,v 1.3 2007/04/05 23:35:39 trevor Exp $
|
9
|
+
#
|
10
|
+
# = About Bio::GCG::Seq
|
11
|
+
#
|
12
|
+
# Please refer document of Bio::GCG::Seq.
|
13
|
+
#
|
14
|
+
|
15
|
+
module Bio
|
16
|
+
module GCG
|
17
|
+
|
18
|
+
#
|
19
|
+
# = Bio::GCG::Seq
|
20
|
+
#
|
21
|
+
# This is GCG sequence file format (.seq or .pep) parser class.
|
22
|
+
#
|
23
|
+
# = References
|
24
|
+
#
|
25
|
+
# * Information about GCG Wisconsin Package(R)
|
26
|
+
# http://www.accelrys.com/products/gcg_wisconsin_package .
|
27
|
+
# * EMBOSS sequence formats
|
28
|
+
# http://www.hgmp.mrc.ac.uk/Software/EMBOSS/Themes/SequenceFormats.html
|
29
|
+
# * BioPerl document
|
30
|
+
# http://docs.bioperl.org/releases/bioperl-1.2.3/Bio/SeqIO/gcg.html
|
31
|
+
class Seq #< DB
|
32
|
+
|
33
|
+
# delimiter used by Bio::FlatFile
|
34
|
+
DELIMITER = RS = nil
|
35
|
+
|
36
|
+
# Creates new instance of this class.
|
37
|
+
# str must be a GCG seq formatted string.
|
38
|
+
def initialize(str)
|
39
|
+
@heading = str[/.*/] # '!!NA_SEQUENCE 1.0' or like this
|
40
|
+
str = str.sub(/.*/, '')
|
41
|
+
str.sub!(/.*\.\.$/m, '')
|
42
|
+
@definition = $&.to_s.sub(/^.*\.\.$/, '').to_s
|
43
|
+
desc = $&.to_s
|
44
|
+
if m = /(.+)\s+Length\:\s+(\d+)\s+(.+)\s+Type\:\s+(\w)\s+Check\:\s+(\d+)/.match(desc) then
|
45
|
+
@entry_id = m[1].to_s.strip
|
46
|
+
@length = (m[2] ? m[2].to_i : nil)
|
47
|
+
@date = m[3].to_s.strip
|
48
|
+
@seq_type = m[4]
|
49
|
+
@checksum = (m[5] ? m[5].to_i : nil)
|
50
|
+
end
|
51
|
+
@data = str
|
52
|
+
@seq = nil
|
53
|
+
@definition.strip!
|
54
|
+
end
|
55
|
+
|
56
|
+
# ID field.
|
57
|
+
attr_reader :entry_id
|
58
|
+
|
59
|
+
# Description field.
|
60
|
+
attr_reader :definition
|
61
|
+
|
62
|
+
# "Length:" field.
|
63
|
+
# Note that sometimes this might differ from real sequence length.
|
64
|
+
attr_reader :length
|
65
|
+
|
66
|
+
# Date field of this entry.
|
67
|
+
attr_reader :date
|
68
|
+
|
69
|
+
# "Type:" field, which indicates sequence type.
|
70
|
+
# "N" means nucleic acid sequence, "P" means protein sequence.
|
71
|
+
attr_reader :seq_type
|
72
|
+
|
73
|
+
# "Check:" field, which indicates checksum of current sequence.
|
74
|
+
attr_reader :checksum
|
75
|
+
|
76
|
+
# heading
|
77
|
+
# ('!!NA_SEQUENCE 1.0' or whatever like this)
|
78
|
+
attr_reader :heading
|
79
|
+
|
80
|
+
#---
|
81
|
+
## data (internally used, will be obsoleted)
|
82
|
+
#attr_reader :data
|
83
|
+
#+++
|
84
|
+
|
85
|
+
# Sequence data.
|
86
|
+
# The class of the sequence is Bio::Sequence::NA, Bio::Sequence::AA
|
87
|
+
# or Bio::Sequence::Generic, according to the sequence type.
|
88
|
+
def seq
|
89
|
+
unless @seq then
|
90
|
+
case @seq_type
|
91
|
+
when 'N', 'n'
|
92
|
+
k = Bio::Sequence::NA
|
93
|
+
when 'P', 'p'
|
94
|
+
k = Bio::Sequence::AA
|
95
|
+
else
|
96
|
+
k = Bio::Sequence
|
97
|
+
end
|
98
|
+
@seq = k.new(@data.tr('^-a-zA-Z.~', ''))
|
99
|
+
end
|
100
|
+
@seq
|
101
|
+
end
|
102
|
+
|
103
|
+
# If you know the sequence is AA, use this method.
|
104
|
+
# Returns a Bio::Sequence::AA object.
|
105
|
+
#
|
106
|
+
# If you call naseq for protein sequence,
|
107
|
+
# or aaseq for nucleic sequence, RuntimeError will be raised.
|
108
|
+
def aaseq
|
109
|
+
if seq.is_a?(Bio::Sequence::AA) then
|
110
|
+
@seq
|
111
|
+
else
|
112
|
+
raise 'seq_type != \'P\''
|
113
|
+
end
|
114
|
+
end
|
115
|
+
|
116
|
+
# If you know the sequence is NA, use this method.
|
117
|
+
# Returens a Bio::Sequence::NA object.
|
118
|
+
#
|
119
|
+
# If you call naseq for protein sequence,
|
120
|
+
# or aaseq for nucleic sequence, RuntimeError will be raised.
|
121
|
+
def naseq
|
122
|
+
if seq.is_a?(Bio::Sequence::NA) then
|
123
|
+
@seq
|
124
|
+
else
|
125
|
+
raise 'seq_type != \'N\''
|
126
|
+
end
|
127
|
+
end
|
128
|
+
|
129
|
+
# Validates checksum.
|
130
|
+
# If validation succeeds, returns true.
|
131
|
+
# Otherwise, returns false.
|
132
|
+
def validate_checksum
|
133
|
+
checksum == self.class.calc_checksum(seq)
|
134
|
+
end
|
135
|
+
|
136
|
+
#---
|
137
|
+
# class methods
|
138
|
+
#+++
|
139
|
+
|
140
|
+
# Calculates checksum from given string.
|
141
|
+
def self.calc_checksum(str)
|
142
|
+
# Reference: Bio::SeqIO::gcg of BioPerl-1.2.3
|
143
|
+
idx = 0
|
144
|
+
sum = 0
|
145
|
+
str.upcase.tr('^A-Z.~', '').each_byte do |c|
|
146
|
+
idx += 1
|
147
|
+
sum += idx * c
|
148
|
+
idx = 0 if idx >= 57
|
149
|
+
end
|
150
|
+
(sum % 10000)
|
151
|
+
end
|
152
|
+
|
153
|
+
# Creates a new GCG sequence format text.
|
154
|
+
# Parameters can be omitted.
|
155
|
+
#
|
156
|
+
# Examples:
|
157
|
+
# Bio::GCG::Seq.to_gcg(:definition=>'H.sapiens DNA',
|
158
|
+
# :seq_type=>'N', :entry_id=>'gi-1234567',
|
159
|
+
# :seq=>seq, :date=>date)
|
160
|
+
#
|
161
|
+
def self.to_gcg(hash)
|
162
|
+
seq = hash[:seq]
|
163
|
+
if seq.is_a?(Bio::Sequence::NA) then
|
164
|
+
seq_type = 'N'
|
165
|
+
elsif seq.is_a?(Bio::Sequence::AA) then
|
166
|
+
seq_type = 'P'
|
167
|
+
else
|
168
|
+
seq_type = (hash[:seq_type] or 'P')
|
169
|
+
end
|
170
|
+
if seq_type == 'N' then
|
171
|
+
head = '!!NA_SEQUENCE 1.0'
|
172
|
+
else
|
173
|
+
head = '!!AA_SEQUENCE 1.0'
|
174
|
+
end
|
175
|
+
date = (hash[:date] or Time.now.strftime('%B %d, %Y %H:%M'))
|
176
|
+
entry_id = hash[:entry_id].to_s.strip
|
177
|
+
len = seq.length
|
178
|
+
checksum = self.calc_checksum(seq)
|
179
|
+
definition = hash[:definition].to_s.strip
|
180
|
+
seq = seq.upcase.gsub(/.{1,50}/, "\\0\n")
|
181
|
+
seq.gsub!(/.{10}/, "\\0 ")
|
182
|
+
w = len.to_s.size + 1
|
183
|
+
i = 1
|
184
|
+
seq.gsub!(/^/) { |x| s = sprintf("\n%*d ", w, i); i += 50; s }
|
185
|
+
|
186
|
+
[ head, "\n", definition, "\n\n",
|
187
|
+
"#{entry_id} Length: #{len} #{date} " \
|
188
|
+
"Type: #{seq_type} Check: #{checksum} ..\n",
|
189
|
+
seq, "\n" ].join('')
|
190
|
+
end
|
191
|
+
|
192
|
+
end #class Seq
|
193
|
+
end #module GCG
|
194
|
+
end #module Bio
|
195
|
+
|
@@ -1,36 +1,18 @@
|
|
1
1
|
#
|
2
2
|
# = bio/appl/genscan/report.rb - Genscan report classes
|
3
3
|
#
|
4
|
-
# Copyright:: Copyright (C) 2003
|
5
|
-
#
|
4
|
+
# Copyright:: Copyright (C) 2003
|
5
|
+
# Mitsuteru C. Nakao <n@bioruby.org>
|
6
|
+
# License:: The Ruby License
|
6
7
|
#
|
7
|
-
# $Id: report.rb,v 1.
|
8
|
+
# $Id: report.rb,v 1.10 2007/04/05 23:35:39 trevor Exp $
|
8
9
|
#
|
9
10
|
# == Description
|
10
11
|
#
|
11
12
|
#
|
12
13
|
# == Example
|
13
|
-
# == References
|
14
|
-
#
|
15
|
-
#--
|
16
|
-
#
|
17
|
-
# This library is free software; you can redistribute it and/or
|
18
|
-
# modify it under the terms of the GNU Lesser General Public
|
19
|
-
# License as published by the Free Software Foundation; either
|
20
|
-
# version 2 of the License, or (at your option) any later version.
|
21
|
-
#
|
22
|
-
# This library is distributed in the hope that it will be useful,
|
23
|
-
# but WITHOUT ANY WARRANTY; without even the implied warranty of
|
24
|
-
# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU
|
25
|
-
# Lesser General Public License for more details.
|
26
14
|
#
|
27
|
-
#
|
28
|
-
# License along with this library; if not, write to the Free Software
|
29
|
-
# Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA
|
30
|
-
#
|
31
|
-
# $Id: report.rb,v 1.8 2005/12/18 15:58:40 k Exp $
|
32
|
-
#
|
33
|
-
#++
|
15
|
+
# == References
|
34
16
|
#
|
35
17
|
|
36
18
|
require 'bio/db/fasta'
|
data/lib/bio/appl/hmmer.rb
CHANGED
@@ -2,47 +2,10 @@
|
|
2
2
|
# = bio/appl/hmmer.rb - HMMER wrapper
|
3
3
|
#
|
4
4
|
# Copyright:: Copyright (C) 2002
|
5
|
-
#
|
6
|
-
#
|
5
|
+
# Toshiaki Katayama <k@bioruby.org>
|
6
|
+
# License:: The Ruby License
|
7
7
|
#
|
8
|
-
# $Id: hmmer.rb,v 1.
|
9
|
-
#
|
10
|
-
# == Description
|
11
|
-
#
|
12
|
-
# A wrapper for the HMMER programs (hmmsearch or hmmpfam).
|
13
|
-
#
|
14
|
-
# == Examples
|
15
|
-
#
|
16
|
-
# require 'bio'
|
17
|
-
# program = 'hmmsearch' # or 'hmmpfam'
|
18
|
-
# hmmfile = 'test.hmm'
|
19
|
-
# seqfile = 'test.faa'
|
20
|
-
#
|
21
|
-
# factory = Bio::HMMER.new(program, hmmfile, seqfile)
|
22
|
-
# p factory.query
|
23
|
-
#
|
24
|
-
# == References
|
25
|
-
#
|
26
|
-
# * HMMER
|
27
|
-
# http://hmmer.wustl.edu/
|
28
|
-
#
|
29
|
-
#--
|
30
|
-
#
|
31
|
-
# This library is free software; you can redistribute it and/or
|
32
|
-
# modify it under the terms of the GNU Lesser General Public
|
33
|
-
# License as published by the Free Software Foundation; either
|
34
|
-
# version 2 of the License, or (at your option) any later version.
|
35
|
-
#
|
36
|
-
# This library is distributed in the hope that it will be useful,
|
37
|
-
# but WITHOUT ANY WARRANTY; without even the implied warranty of
|
38
|
-
# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU
|
39
|
-
# Lesser General Public License for more details.
|
40
|
-
#
|
41
|
-
# You should have received a copy of the GNU Lesser General Public
|
42
|
-
# License along with this library; if not, write to the Free Software
|
43
|
-
# Foundation, Inc., 59 Temple Place, Suite 330, Boston, MA 02111-1307 USA
|
44
|
-
#
|
45
|
-
#++
|
8
|
+
# $Id: hmmer.rb,v 1.9 2007/04/05 23:35:39 trevor Exp $
|
46
9
|
#
|
47
10
|
|
48
11
|
require 'bio/command'
|
@@ -50,6 +13,8 @@ require 'shellwords'
|
|
50
13
|
|
51
14
|
module Bio
|
52
15
|
|
16
|
+
# == Description
|
17
|
+
#
|
53
18
|
# A wapper for HMMER programs (hmmsearch or hmmpfam).
|
54
19
|
#
|
55
20
|
# === Examples
|
@@ -61,7 +26,7 @@ module Bio
|
|
61
26
|
#
|
62
27
|
# factory = Bio::HMMER.new(program, hmmfile, seqfile)
|
63
28
|
# report = factory.query
|
64
|
-
# report.class
|
29
|
+
# report.class # => Bio::HMMER::Report
|
65
30
|
#
|
66
31
|
# === References
|
67
32
|
#
|
@@ -72,8 +37,6 @@ class HMMER
|
|
72
37
|
|
73
38
|
autoload :Report, 'bio/appl/hmmer/report'
|
74
39
|
|
75
|
-
include Bio::Command::Tools
|
76
|
-
|
77
40
|
# Prgrams name. (hmmsearch or hmmpfam).
|
78
41
|
attr_accessor :program
|
79
42
|
|
@@ -112,7 +75,7 @@ class HMMER
|
|
112
75
|
# Gets options by String.
|
113
76
|
# backward compatibility.
|
114
77
|
def option
|
115
|
-
make_command_line(@options)
|
78
|
+
Bio::Command.make_command_line(@options)
|
116
79
|
end
|
117
80
|
|
118
81
|
|
@@ -131,7 +94,7 @@ class HMMER
|
|
131
94
|
|
132
95
|
report = nil
|
133
96
|
|
134
|
-
@output =
|
97
|
+
@output = Bio::Command.query_command(cmd, nil)
|
135
98
|
report = parse_result(@output)
|
136
99
|
|
137
100
|
return report
|