npm - jbrowse-plugin-msaview - Versions diffs - 2.2.8 → 2.3.2 - Mend

jbrowse-plugin-msaview 2.2.8 → 2.3.2

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.

Files changed (134) hide show

package/dist/jbrowse-plugin-msaview.umd.production.min.js CHANGED Viewed

@@ -1,13 +1,13 @@
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if(m>0){if(!De.compareByGeneratedPositionsInflated(l,f[m-1]))continue;c+=","}c+=Yi.encode(l.generatedColumn-t),t=l.generatedColumn,l.source!=null&&(u=this._sources.indexOf(l.source),c+=Yi.encode(u-s),s=u,c+=Yi.encode(l.originalLine-1-o),o=l.originalLine-1,c+=Yi.encode(l.originalColumn-n),n=l.originalColumn,l.name!=null&&(A=this._names.indexOf(l.name),c+=Yi.encode(A-i),i=A)),a+=c}return a};or.prototype._generateSourcesContent=function(t,r){return t.map(function(n){if(!this._sourcesContents)return null;r!=null&&(n=De.relative(r,n));var o=De.toSetString(n);return Object.prototype.hasOwnProperty.call(this._sourcesContents,o)?this._sourcesContents[o]:null},this)};or.prototype.toJSON=function(){var t={version:this._version,sources:this._sources.toArray(),names:this._names.toArray(),mappings:this._serializeMappings()};return this._file!=null&&(t.file=this._file),this._sourceRoot!=null&&(t.sourceRoot=this._sourceRoot),this._sourcesContents&&(t.sourcesContent=this._generateSourcesContent(t.sources,t.sourceRoot)),t};or.prototype.toString=function(){return JSON.stringify(this.toJSON())};zC.SourceMapGenerator=or});var $C=H(Xn=>{Xn.GREATEST_LOWER_BOUND=1;Xn.LEAST_UPPER_BOUND=2;function wu(e,t,r,n,o,i){var s=Math.floor((t-e)/2)+e,a=o(r,n[s],!0);return a===0?s:a>0?t-s>1?wu(s,t,r,n,o,i):i==Xn.LEAST_UPPER_BOUND?t<n.length?t:-1:s:s-e>1?wu(e,s,r,n,o,i):i==Xn.LEAST_UPPER_BOUND?s:e<0?-1:e}Xn.search=function(t,r,n,o){if(r.length===0)return-1;var i=wu(-1,r.length,t,r,n,o||Xn.GREATEST_LOWER_BOUND);if(i<0)return-1;for(;i-1>=0&&n(r[i],r[i-1],!0)===0;)--i;return i}});var eE=H(ZC=>{function $v(e){function t(o,i,s){var a=o[i];o[i]=o[s],o[s]=a}function r(o,i){return Math.round(o+Math.random()*(i-o))}function n(o,i,s,a){if(s<a){var c=r(s,a),l=s-1;t(o,c,a);for(var A=o[a],u=s;u<a;u++)i(o[u],A,!1)<=0&&(l+=1,t(o,l,u));t(o,l+1,u);var f=l+1;n(o,i,s,f-1),n(o,i,f+1,a)}}return n}function Xv(e){let t=$v.toString();return new Function(`return ${t}`)()(e)}var XC=new WeakMap;ZC.quickSort=function(e,t,r=0){let n=XC.get(t);n===void 0&&(n=Xv(t),XC.set(t,n)),n(e,t,r,e.length-1)}});var nE=H(Za=>{var L=zo(),bu=$C(),$o=xu().ArraySet,Zv=hu(),qi=eE().quickSort;function Ce(e,t){var r=e;return typeof e=="string"&&(r=L.parseSourceMapInput(e)),r.sections!=null?new Cr(r,t):new at(r,t)}Ce.fromSourceMap=function(e,t){return at.fromSourceMap(e,t)};Ce.prototype._version=3;Ce.prototype.__generatedMappings=null;Object.defineProperty(Ce.prototype,"_generatedMappings",{configurable:!0,enumerable:!0,get:function(){return this.__generatedMappings||this._parseMappings(this._mappings,this.sourceRoot),this.__generatedMappings}});Ce.prototype.__originalMappings=null;Object.defineProperty(Ce.prototype,"_originalMappings",{configurable:!0,enumerable:!0,get:function(){return this.__originalMappings||this._parseMappings(this._mappings,this.sourceRoot),this.__originalMappings}});Ce.prototype._charIsMappingSeparator=function(t,r){var n=t.charAt(r);return n===";"||n===","};Ce.prototype._parseMappings=function(t,r){throw new Error("Subclasses must implement _parseMappings")};Ce.GENERATED_ORDER=1;Ce.ORIGINAL_ORDER=2;Ce.GREATEST_LOWER_BOUND=1;Ce.LEAST_UPPER_BOUND=2;Ce.prototype.eachMapping=function(t,r,n){var o=r||null,i=n||Ce.GENERATED_ORDER,s;switch(i){case Ce.GENERATED_ORDER:s=this._generatedMappings;break;case Ce.ORIGINAL_ORDER:s=this._originalMappings;break;default:throw new Error("Unknown order of iteration.")}for(var a=this.sourceRoot,c=t.bind(o),l=this._names,A=this._sources,u=this._sourceMapURL,f=0,m=s.length;f<m;f++){var g=s[f],h=g.source===null?null:A.at(g.source);h!==null&&(h=L.computeSourceURL(a,h,u)),c({source:h,generatedLine:g.generatedLine,generatedColumn:g.generatedColumn,originalLine:g.originalLine,originalColumn:g.originalColumn,name:g.name===null?null:l.at(g.name)})}};Ce.prototype.allGeneratedPositionsFor=function(t){var r=L.getArg(t,"line"),n={source:L.getArg(t,"source"),originalLine:r,originalColumn:L.getArg(t,"column",0)};if(n.source=this._findSourceIndex(n.source),n.source<0)return[];var o=[],i=this._findMapping(n,this._originalMappings,"originalLine","originalColumn",L.compareByOriginalPositions,bu.LEAST_UPPER_BOUND);if(i>=0){var s=this._originalMappings[i];if(t.column===void 0)for(var a=s.originalLine;s&&s.originalLine===a;)o.push({line:L.getArg(s,"generatedLine",null),column:L.getArg(s,"generatedColumn",null),lastColumn:L.getArg(s,"lastGeneratedColumn",null)}),s=this._originalMappings[++i];else for(var c=s.originalColumn;s&&s.originalLine===r&&s.originalColumn==c;)o.push({line:L.getArg(s,"generatedLine",null),column:L.getArg(s,"generatedColumn",null),lastColumn:L.getArg(s,"lastGeneratedColumn",null)}),s=this._originalMappings[++i]}return o};Za.SourceMapConsumer=Ce;function at(e,t){var r=e;typeof e=="string"&&(r=L.parseSourceMapInput(e));var n=L.getArg(r,"version"),o=L.getArg(r,"sources"),i=L.getArg(r,"names",[]),s=L.getArg(r,"sourceRoot",null),a=L.getArg(r,"sourcesContent",null),c=L.getArg(r,"mappings"),l=L.getArg(r,"file",null);if(n!=this._version)throw new Error("Unsupported version: "+n);s&&(s=L.normalize(s)),o=o.map(String).map(L.normalize).map(function(A){return s&&L.isAbsolute(s)&&L.isAbsolute(A)?L.relative(s,A):A}),this._names=$o.fromArray(i.map(String),!0),this._sources=$o.fromArray(o,!0),this._absoluteSources=this._sources.toArray().map(function(A){return L.computeSourceURL(s,A,t)}),this.sourceRoot=s,this.sourcesContent=a,this._mappings=c,this._sourceMapURL=t,this.file=l}at.prototype=Object.create(Ce.prototype);at.prototype.consumer=Ce;at.prototype._findSourceIndex=function(e){var t=e;if(this.sourceRoot!=null&&(t=L.relative(this.sourceRoot,t)),this._sources.has(t))return this._sources.indexOf(t);var r;for(r=0;r<this._absoluteSources.length;++r)if(this._absoluteSources[r]==e)return r;return-1};at.fromSourceMap=function(t,r){var n=Object.create(at.prototype),o=n._names=$o.fromArray(t._names.toArray(),!0),i=n._sources=$o.fromArray(t._sources.toArray(),!0);n.sourceRoot=t._sourceRoot,n.sourcesContent=t._generateSourcesContent(n._sources.toArray(),n.sourceRoot),n.file=t._file,n._sourceMapURL=r,n._absoluteSources=n._sources.toArray().map(function(m){return L.computeSourceURL(n.sourceRoot,m,r)});for(var s=t._mappings.toArray().slice(),a=n.__generatedMappings=[],c=n.__originalMappings=[],l=0,A=s.length;l<A;l++){var u=s[l],f=new rE;f.generatedLine=u.generatedLine,f.generatedColumn=u.generatedColumn,u.source&&(f.source=i.indexOf(u.source),f.originalLine=u.originalLine,f.originalColumn=u.originalColumn,u.name&&(f.name=o.indexOf(u.name)),c.push(f)),a.push(f)}return qi(n.__originalMappings,L.compareByOriginalPositions),n};at.prototype._version=3;Object.defineProperty(at.prototype,"sources",{get:function(){return this._absoluteSources.slice()}});function rE(){this.generatedLine=0,this.generatedColumn=0,this.source=null,this.originalLine=null,this.originalColumn=null,this.name=null}var Bu=L.compareByGeneratedPositionsDeflatedNoLine;function tE(e,t){let r=e.length,n=e.length-t;if(!(n<=1))if(n==2){let o=e[t],i=e[t+1];Bu(o,i)>0&&(e[t]=i,e[t+1]=o)}else if(n<20)for(let o=t;o<r;o++)for(let i=o;i>t;i--){let s=e[i-1],a=e[i];if(Bu(s,a)<=0)break;e[i-1]=a,e[i]=s}else qi(e,Bu,t)}at.prototype._parseMappings=function(t,r){var n=1,o=0,i=0,s=0,a=0,c=0,l=t.length,A=0,u={},f={},m=[],g=[],h,E,C,x,y;let w=0;for(;A<l;)if(t.charAt(A)===";")n++,A++,o=0,tE(g,w),w=g.length;else if(t.charAt(A)===",")A++;else{for(h=new rE,h.generatedLine=n,x=A;x<l&&!this._charIsMappingSeparator(t,x);x++);for(E=t.slice(A,x),C=[];A<x;)Zv.decode(t,A,f),y=f.value,A=f.rest,C.push(y);if(C.length===2)throw new Error("Found a source, but no line and column");if(C.length===3)throw new Error("Found a source and line, but no column");if(h.generatedColumn=o+C[0],o=h.generatedColumn,C.length>1&&(h.source=a+C[1],a+=C[1],h.originalLine=i+C[2],i=h.originalLine,h.originalLine+=1,h.originalColumn=s+C[3],s=h.originalColumn,C.length>4&&(h.name=c+C[4],c+=C[4])),g.push(h),typeof h.originalLine=="number"){let S=h.source;for(;m.length<=S;)m.push(null);m[S]===null&&(m[S]=[]),m[S].push(h)}}tE(g,w),this.__generatedMappings=g;for(var B=0;B<m.length;B++)m[B]!=null&&qi(m[B],L.compareByOriginalPositionsNoSource);this.__originalMappings=[].concat(...m)};at.prototype._findMapping=function(t,r,n,o,i,s){if(t[n]<=0)throw new TypeError("Line must be greater than or equal to 1, got "+t[n]);if(t[o]<0)throw new TypeError("Column must be greater than or equal to 0, got "+t[o]);return bu.search(t,r,i,s)};at.prototype.computeColumnSpans=function(){for(var t=0;t<this._generatedMappings.length;++t){var r=this._generatedMappings[t];if(t+1<this._generatedMappings.length){var n=this._generatedMappings[t+1];if(r.generatedLine===n.generatedLine){r.lastGeneratedColumn=n.generatedColumn-1;continue}}r.lastGeneratedColumn=1/0}};at.prototype.originalPositionFor=function(t){var r={generatedLine:L.getArg(t,"line"),generatedColumn:L.getArg(t,"column")},n=this._findMapping(r,this._generatedMappings,"generatedLine","generatedColumn",L.compareByGeneratedPositionsDeflated,L.getArg(t,"bias",Ce.GREATEST_LOWER_BOUND));if(n>=0){var o=this._generatedMappings[n];if(o.generatedLine===r.generatedLine){var i=L.getArg(o,"source",null);i!==null&&(i=this._sources.at(i),i=L.computeSourceURL(this.sourceRoot,i,this._sourceMapURL));var s=L.getArg(o,"name",null);return s!==null&&(s=this._names.at(s)),{source:i,line:L.getArg(o,"originalLine",null),column:L.getArg(o,"originalColumn",null),name:s}}}return{source:null,line:null,column:null,name:null}};at.prototype.hasContentsOfAllSources=function(){return this.sourcesContent?this.sourcesContent.length>=this._sources.size()&&!this.sourcesContent.some(function(t){return t==null}):!1};at.prototype.sourceContentFor=function(t,r){if(!this.sourcesContent)return null;var n=this._findSourceIndex(t);if(n>=0)return this.sourcesContent[n];var o=t;this.sourceRoot!=null&&(o=L.relative(this.sourceRoot,o));var i;if(this.sourceRoot!=null&&(i=L.urlParse(this.sourceRoot))){var s=o.replace(/^file:\/\//,"");if(i.scheme=="file"&&this._sources.has(s))return this.sourcesContent[this._sources.indexOf(s)];if((!i.path||i.path=="/")&&this._sources.has("/"+o))return this.sourcesContent[this._sources.indexOf("/"+o)]}if(r)return null;throw new Error('"'+o+'" is not in the SourceMap.')};at.prototype.generatedPositionFor=function(t){var r=L.getArg(t,"source");if(r=this._findSourceIndex(r),r<0)return{line:null,column:null,lastColumn:null};var n={source:r,originalLine:L.getArg(t,"line"),originalColumn:L.getArg(t,"column")},o=this._findMapping(n,this._originalMappings,"originalLine","originalColumn",L.compareByOriginalPositions,L.getArg(t,"bias",Ce.GREATEST_LOWER_BOUND));if(o>=0){var i=this._originalMappings[o];if(i.source===n.source)return{line:L.getArg(i,"generatedLine",null),column:L.getArg(i,"generatedColumn",null),lastColumn:L.getArg(i,"lastGeneratedColumn",null)}}return{line:null,column:null,lastColumn:null}};Za.BasicSourceMapConsumer=at;function Cr(e,t){var r=e;typeof e=="string"&&(r=L.parseSourceMapInput(e));var n=L.getArg(r,"version"),o=L.getArg(r,"sections");if(n!=this._version)throw new Error("Unsupported version: "+n);this._sources=new $o,this._names=new $o;var i={line:-1,column:0};this._sections=o.map(function(s){if(s.url)throw new Error("Support for url field in sections not implemented.");var a=L.getArg(s,"offset"),c=L.getArg(a,"line"),l=L.getArg(a,"column");if(c<i.line||c===i.line&&l<i.column)throw new Error("Section offsets must be ordered and non-overlapping.");return i=a,{generatedOffset:{generatedLine:c+1,generatedColumn:l+1},consumer:new Ce(L.getArg(s,"map"),t)}})}Cr.prototype=Object.create(Ce.prototype);Cr.prototype.constructor=Ce;Cr.prototype._version=3;Object.defineProperty(Cr.prototype,"sources",{get:function(){for(var e=[],t=0;t<this._sections.length;t++)for(var r=0;r<this._sections[t].consumer.sources.length;r++)e.push(this._sections[t].consumer.sources[r]);return e}});Cr.prototype.originalPositionFor=function(t){var r={generatedLine:L.getArg(t,"line"),generatedColumn:L.getArg(t,"column")},n=bu.search(r,this._sections,function(i,s){var a=i.generatedLine-s.generatedOffset.generatedLine;return a||i.generatedColumn-s.generatedOffset.generatedColumn}),o=this._sections[n];return o?o.consumer.originalPositionFor({line:r.generatedLine-(o.generatedOffset.generatedLine-1),column:r.generatedColumn-(o.generatedOffset.generatedLine===r.generatedLine?o.generatedOffset.generatedColumn-1:0),bias:t.bias}):{source:null,line:null,column:null,name:null}};Cr.prototype.hasContentsOfAllSources=function(){return this._sections.every(function(t){return t.consumer.hasContentsOfAllSources()})};Cr.prototype.sourceContentFor=function(t,r){for(var n=0;n<this._sections.length;n++){var o=this._sections[n],i=o.consumer.sourceContentFor(t,!0);if(i||i==="")return i}if(r)return null;throw new Error('"'+t+'" is not in the SourceMap.')};Cr.prototype.generatedPositionFor=function(t){for(var r=0;r<this._sections.length;r++){var n=this._sections[r];if(n.consumer._findSourceIndex(L.getArg(t,"source"))!==-1){var o=n.consumer.generatedPositionFor(t);if(o){var i={line:o.line+(n.generatedOffset.generatedLine-1),column:o.column+(n.generatedOffset.generatedLine===o.line?n.generatedOffset.generatedColumn-1:0)};return i}}}return{line:null,column:null}};Cr.prototype._parseMappings=function(t,r){this.__generatedMappings=[],this.__originalMappings=[];for(var n=0;n<this._sections.length;n++)for(var o=this._sections[n],i=o.consumer._generatedMappings,s=0;s<i.length;s++){var a=i[s],c=o.consumer._sources.at(a.source);c!==null&&(c=L.computeSourceURL(o.consumer.sourceRoot,c,this._sourceMapURL)),this._sources.add(c),c=this._sources.indexOf(c);var l=null;a.name&&(l=o.consumer._names.at(a.name),this._names.add(l),l=this._names.indexOf(l));var A={source:c,generatedLine:a.generatedLine+(o.generatedOffset.generatedLine-1),generatedColumn:a.generatedColumn+(o.generatedOffset.generatedLine===a.generatedLine?o.generatedOffset.generatedColumn-1:0),originalLine:a.originalLine,originalColumn:a.originalColumn,name:l};this.__generatedMappings.push(A),typeof A.originalLine=="number"&&this.__originalMappings.push(A)}qi(this.__generatedMappings,L.compareByGeneratedPositionsDeflated),qi(this.__originalMappings,L.compareByOriginalPositions)};Za.IndexedSourceMapConsumer=Cr});var iE=H(oE=>{var e2=yu().SourceMapGenerator,ec=zo(),t2=/(\r?\n)/,r2=10,Xo="$$$isSourceNode$$$";function Ot(e,t,r,n,o){this.children=[],this.sourceContents={},this.line=e??null,this.column=t??null,this.source=r??null,this.name=o??null,this[Xo]=!0,n!=null&&this.add(n)}Ot.fromStringWithSourceMap=function(t,r,n){var o=new Ot,i=t.split(t2),s=0,a=function(){var f=g(),m=g()||"";return f+m;function g(){return s<i.length?i[s++]:void 0}},c=1,l=0,A=null;return r.eachMapping(function(f){if(A!==null)if(c<f.generatedLine)u(A,a()),c++,l=0;else{var m=i[s]||"",g=m.substr(0,f.generatedColumn-l);i[s]=m.substr(f.generatedColumn-l),l=f.generatedColumn,u(A,g),A=f;return}for(;c<f.generatedLine;)o.add(a()),c++;if(l<f.generatedColumn){var m=i[s]||"";o.add(m.substr(0,f.generatedColumn)),i[s]=m.substr(f.generatedColumn),l=f.generatedColumn}A=f},this),s<i.length&&(A&&u(A,a()),o.add(i.splice(s).join(""))),r.sources.forEach(function(f){var m=r.sourceContentFor(f);m!=null&&(n!=null&&(f=ec.join(n,f)),o.setSourceContent(f,m))}),o;function u(f,m){if(f===null||f.source===void 0)o.add(m);else{var g=n?ec.join(n,f.source):f.source;o.add(new Ot(f.originalLine,f.originalColumn,g,m,f.name))}}};Ot.prototype.add=function(t){if(Array.isArray(t))t.forEach(function(r){this.add(r)},this);else if(t[Xo]||typeof t=="string")t&&this.children.push(t);else throw new TypeError("Expected a SourceNode, string, or an array of SourceNodes and strings. Got "+t);return this};Ot.prototype.prepend=function(t){if(Array.isArray(t))for(var r=t.length-1;r>=0;r--)this.prepend(t[r]);else if(t[Xo]||typeof t=="string")this.children.unshift(t);else throw new TypeError("Expected a SourceNode, string, or an array of SourceNodes and strings. Got "+t);return this};Ot.prototype.walk=function(t){for(var r,n=0,o=this.children.length;n<o;n++)r=this.children[n],r[Xo]?r.walk(t):r!==""&&t(r,{source:this.source,line:this.line,column:this.column,name:this.name})};Ot.prototype.join=function(t){var r,n,o=this.children.length;if(o>0){for(r=[],n=0;n<o-1;n++)r.push(this.children[n]),r.push(t);r.push(this.children[n]),this.children=r}return this};Ot.prototype.replaceRight=function(t,r){var n=this.children[this.children.length-1];return n[Xo]?n.replaceRight(t,r):typeof n=="string"?this.children[this.children.length-1]=n.replace(t,r):this.children.push("".replace(t,r)),this};Ot.prototype.setSourceContent=function(t,r){this.sourceContents[ec.toSetString(t)]=r};Ot.prototype.walkSourceContents=function(t){for(var r=0,n=this.children.length;r<n;r++)this.children[r][Xo]&&this.children[r].walkSourceContents(t);for(var o=Object.keys(this.sourceContents),r=0,n=o.length;r<n;r++)t(ec.fromSetString(o[r]),this.sourceContents[o[r]])};Ot.prototype.toString=function(){var t="";return this.walk(function(r){t+=r}),t};Ot.prototype.toStringWithSourceMap=function(t){var r={code:"",line:1,column:0},n=new e2(t),o=!1,i=null,s=null,a=null,c=null;return this.walk(function(l,A){r.code+=l,A.source!==null&&A.line!==null&&A.column!==null?((i!==A.source||s!==A.line||a!==A.column||c!==A.name)&&n.addMapping({source:A.source,original:{line:A.line,column:A.column},generated:{line:r.line,column:r.column},name:A.name}),i=A.source,s=A.line,a=A.column,c=A.name,o=!0):o&&(n.addMapping({generated:{line:r.line,column:r.column}}),i=null,o=!1);for(var u=0,f=l.length;u<f;u++)l.charCodeAt(u)===r2?(r.line++,r.column=0,u+1===f?(i=null,o=!1):o&&n.addMapping({source:A.source,original:{line:A.line,column:A.column},generated:{line:r.line,column:r.column},name:A.name})):r.column++}),this.walkSourceContents(function(l,A){n.setSourceContent(l,A)}),{code:r.code,map:n}};oE.SourceNode=Ot});var sE=H(tc=>{tc.SourceMapGenerator=yu().SourceMapGenerator;tc.SourceMapConsumer=nE().SourceMapConsumer;tc.SourceNode=iE().SourceNode});function nc(e){let{children:t,...r}=e;return(0,rc.jsxs)(aE.Link,{...r,target:"_blank",rel:"noopener noreferrer",children:[t," ",(0,rc.jsx)(ca,{fontSize:"small"})]})}var rc,aE,cE=p(()=>{rc=d(R(),1);lA();aE=d(N(),1)});function Su({text:e,extra:t}){let{classes:r}=n2(),n=t?`supporting data: ${JSON.stringify(t,null,2)}`:"",o=[e,n].filter(Boolean).join(`
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n=e.generatedLine-t.generatedLine;return n!==0||(n=e.generatedColumn-t.generatedColumn,n!==0||r)||(n=Zr(e.source,t.source),n!==0)||(n=e.originalLine-t.originalLine,n!==0)||(n=e.originalColumn-t.originalColumn,n!==0)?n:Zr(e.name,t.name)}$e.compareByGeneratedPositionsDeflated=Y2;function j2(e,t,r){var n=e.generatedColumn-t.generatedColumn;return n!==0||r||(n=Zr(e.source,t.source),n!==0)||(n=e.originalLine-t.originalLine,n!==0)||(n=e.originalColumn-t.originalColumn,n!==0)?n:Zr(e.name,t.name)}$e.compareByGeneratedPositionsDeflatedNoLine=j2;function Zr(e,t){return e===t?0:e===null?1:t===null?-1:e>t?1:-1}function V2(e,t){var r=e.generatedLine-t.generatedLine;return r!==0||(r=e.generatedColumn-t.generatedColumn,r!==0)||(r=Zr(e.source,t.source),r!==0)||(r=e.originalLine-t.originalLine,r!==0)||(r=e.originalColumn-t.originalColumn,r!==0)?r:Zr(e.name,t.name)}$e.compareByGeneratedPositionsInflated=V2;function W2(e){return JSON.parse(e.replace(/^\)]}'[^\n]*\n/,""))}$e.parseSourceMapInput=W2;function z2(e,t,r){if(t=t||"",e&&(e[e.length-1]!=="/"&&t[0]!=="/"&&(e+="/"),t=e+t),r){var n=qi(r);if(!n)throw new Error("sourceMapURL could not be parsed");if(n.path){var o=n.path.lastIndexOf("/");o>=0&&(n.path=n.path.substring(0,o+1))}t=HC(Xo(n),t)}return Mu(t)}$e.computeSourceURL=z2});var _u=H(jC=>{var vu=Zo(),Tu=Object.prototype.hasOwnProperty,jn=typeof Map<"u";function en(){this._array=[],this._set=jn?new Map:Object.create(null)}en.fromArray=function(t,r){for(var n=new en,o=0,i=t.length;o<i;o++)n.add(t[o],r);return n};en.prototype.size=function(){return jn?this._set.size:Object.getOwnPropertyNames(this._set).length};en.prototype.add=function(t,r){var n=jn?t:vu.toSetString(t),o=jn?this.has(t):Tu.call(this._set,n),i=this._array.length;(!o||r)&&this._array.push(t),o||(jn?this._set.set(t,i):this._set[n]=i)};en.prototype.has=function(t){if(jn)return this._set.has(t);var r=vu.toSetString(t);return Tu.call(this._set,r)};en.prototype.indexOf=function(t){if(jn){var r=this._set.get(t);if(r>=0)return r}else{var n=vu.toSetString(t);if(Tu.call(this._set,n))return this._set[n]}throw new Error('"'+t+'" is not in the set.')};en.prototype.at=function(t){if(t>=0&&t<this._array.length)return this._array[t];throw new Error("No element indexed by "+t)};en.prototype.toArray=function(){return this._array.slice()};jC.ArraySet=en});var zC=H(WC=>{var VC=Zo();function $2(e,t){var r=e.generatedLine,n=t.generatedLine,o=e.generatedColumn,i=t.generatedColumn;return n>r||n==r&&i>=o||VC.compareByGeneratedPositionsInflated(e,t)<=0}function nc(){this._array=[],this._sorted=!0,this._last={generatedLine:-1,generatedColumn:0}}nc.prototype.unsortedForEach=function(t,r){this._array.forEach(t,r)};nc.prototype.add=function(t){$2(this._last,t)?(this._last=t,this._array.push(t)):(this._sorted=!1,this._array.push(t))};nc.prototype.toArray=function(){return this._sorted||(this._array.sort(VC.compareByGeneratedPositionsInflated),this._sorted=!0),this._array};WC.MappingList=nc});var Du=H($C=>{var Yi=Qu(),ke=Zo(),oc=_u().ArraySet,K2=zC().MappingList;function nr(e){e||(e={}),this._file=ke.getArg(e,"file",null),this._sourceRoot=ke.getArg(e,"sourceRoot",null),this._skipValidation=ke.getArg(e,"skipValidation",!1),this._ignoreInvalidMapping=ke.getArg(e,"ignoreInvalidMapping",!1),this._sources=new oc,this._names=new oc,this._mappings=new K2,this._sourcesContents=null}nr.prototype._version=3;nr.fromSourceMap=function(t,r){var n=t.sourceRoot,o=new nr(Object.assign(r||{},{file:t.file,sourceRoot:n}));return t.eachMapping(function(i){var s={generated:{line:i.generatedLine,column:i.generatedColumn}};i.source!=null&&(s.source=i.source,n!=null&&(s.source=ke.relative(n,s.source)),s.original={line:i.originalLine,column:i.originalColumn},i.name!=null&&(s.name=i.name)),o.addMapping(s)}),t.sources.forEach(function(i){var s=i;n!==null&&(s=ke.relative(n,i)),o._sources.has(s)||o._sources.add(s);var a=t.sourceContentFor(i);a!=null&&o.setSourceContent(i,a)}),o};nr.prototype.addMapping=function(t){var r=ke.getArg(t,"generated"),n=ke.getArg(t,"original",null),o=ke.getArg(t,"source",null),i=ke.getArg(t,"name",null);!this._skipValidation&&this._validateMapping(r,n,o,i)===!1||(o!=null&&(o=String(o),this._sources.has(o)||this._sources.add(o)),i!=null&&(i=String(i),this._names.has(i)||this._names.add(i)),this._mappings.add({generatedLine:r.line,generatedColumn:r.column,originalLine:n!=null&&n.line,originalColumn:n!=null&&n.column,source:o,name:i}))};nr.prototype.setSourceContent=function(t,r){var n=t;this._sourceRoot!=null&&(n=ke.relative(this._sourceRoot,n)),r!=null?(this._sourcesContents||(this._sourcesContents=Object.create(null)),this._sourcesContents[ke.toSetString(n)]=r):this._sourcesContents&&(delete this._sourcesContents[ke.toSetString(n)],Object.keys(this._sourcesContents).length===0&&(this._sourcesContents=null))};nr.prototype.applySourceMap=function(t,r,n){var o=r;if(r==null){if(t.file==null)throw new Error(`SourceMapGenerator.prototype.applySourceMap requires either an explicit source file, or the source map's "file" property. Both were omitted.`);o=t.file}var i=this._sourceRoot;i!=null&&(o=ke.relative(i,o));var s=new oc,a=new oc;this._mappings.unsortedForEach(function(c){if(c.source===o&&c.originalLine!=null){var l=t.originalPositionFor({line:c.originalLine,column:c.originalColumn});l.source!=null&&(c.source=l.source,n!=null&&(c.source=ke.join(n,c.source)),i!=null&&(c.source=ke.relative(i,c.source)),c.originalLine=l.line,c.originalColumn=l.column,l.name!=null&&(c.name=l.name))}var A=c.source;A!=null&&!s.has(A)&&s.add(A);var u=c.name;u!=null&&!a.has(u)&&a.add(u)},this),this._sources=s,this._names=a,t.sources.forEach(function(c){var l=t.sourceContentFor(c);l!=null&&(n!=null&&(c=ke.join(n,c)),i!=null&&(c=ke.relative(i,c)),this.setSourceContent(c,l))},this)};nr.prototype._validateMapping=function(t,r,n,o){if(r&&typeof r.line!="number"&&typeof r.column!="number"){var i="original.line and original.column are not numbers -- you probably meant to omit the original mapping entirely and only map the generated position. If so, pass null for the original mapping instead of an object with empty or null values.";if(this._ignoreInvalidMapping)return typeof console<"u"&&console.warn&&console.warn(i),!1;throw new Error(i)}if(!(t&&"line"in t&&"column"in t&&t.line>0&&t.column>=0&&!r&&!n&&!o)){if(t&&"line"in t&&"column"in t&&r&&"line"in r&&"column"in r&&t.line>0&&t.column>=0&&r.line>0&&r.column>=0&&n)return;var i="Invalid mapping: "+JSON.stringify({generated:t,source:n,original:r,name:o});if(this._ignoreInvalidMapping)return typeof console<"u"&&console.warn&&console.warn(i),!1;throw new Error(i)}};nr.prototype._serializeMappings=function(){for(var t=0,r=1,n=0,o=0,i=0,s=0,a="",c,l,A,u,d=this._mappings.toArray(),m=0,g=d.length;m<g;m++){if(l=d[m],c="",l.generatedLine!==r)for(t=0;l.generatedLine!==r;)c+=";",r++;else if(m>0){if(!ke.compareByGeneratedPositionsInflated(l,d[m-1]))continue;c+=","}c+=Yi.encode(l.generatedColumn-t),t=l.generatedColumn,l.source!=null&&(u=this._sources.indexOf(l.source),c+=Yi.encode(u-s),s=u,c+=Yi.encode(l.originalLine-1-o),o=l.originalLine-1,c+=Yi.encode(l.originalColumn-n),n=l.originalColumn,l.name!=null&&(A=this._names.indexOf(l.name),c+=Yi.encode(A-i),i=A)),a+=c}return a};nr.prototype._generateSourcesContent=function(t,r){return t.map(function(n){if(!this._sourcesContents)return null;r!=null&&(n=ke.relative(r,n));var o=ke.toSetString(n);return Object.prototype.hasOwnProperty.call(this._sourcesContents,o)?this._sourcesContents[o]:null},this)};nr.prototype.toJSON=function(){var t={version:this._version,sources:this._sources.toArray(),names:this._names.toArray(),mappings:this._serializeMappings()};return this._file!=null&&(t.file=this._file),this._sourceRoot!=null&&(t.sourceRoot=this._sourceRoot),this._sourcesContents&&(t.sourcesContent=this._generateSourcesContent(t.sources,t.sourceRoot)),t};nr.prototype.toString=function(){return JSON.stringify(this.toJSON())};$C.SourceMapGenerator=nr});var KC=H(Vn=>{Vn.GREATEST_LOWER_BOUND=1;Vn.LEAST_UPPER_BOUND=2;function ku(e,t,r,n,o,i){var s=Math.floor((t-e)/2)+e,a=o(r,n[s],!0);return a===0?s:a>0?t-s>1?ku(s,t,r,n,o,i):i==Vn.LEAST_UPPER_BOUND?t<n.length?t:-1:s:s-e>1?ku(e,s,r,n,o,i):i==Vn.LEAST_UPPER_BOUND?s:e<0?-1:e}Vn.search=function(t,r,n,o){if(r.length===0)return-1;var i=ku(-1,r.length,t,r,n,o||Vn.GREATEST_LOWER_BOUND);if(i<0)return-1;for(;i-1>=0&&n(r[i],r[i-1],!0)===0;)--i;return i}});var eE=H(ZC=>{function X2(e){function t(o,i,s){var a=o[i];o[i]=o[s],o[s]=a}function r(o,i){return Math.round(o+Math.random()*(i-o))}function n(o,i,s,a){if(s<a){var c=r(s,a),l=s-1;t(o,c,a);for(var A=o[a],u=s;u<a;u++)i(o[u],A,!1)<=0&&(l+=1,t(o,l,u));t(o,l+1,u);var d=l+1;n(o,i,s,d-1),n(o,i,d+1,a)}}return n}function Z2(e){let t=X2.toString();return new Function(`return ${t}`)()(e)}var XC=new WeakMap;ZC.quickSort=function(e,t,r=0){let n=XC.get(t);n===void 0&&(n=Z2(t),XC.set(t,n)),n(e,t,r,e.length-1)}});var nE=H(ic=>{var D=Zo(),Lu=KC(),ei=_u().ArraySet,ev=Qu(),ji=eE().quickSort;function he(e,t){var r=e;return typeof e=="string"&&(r=D.parseSourceMapInput(e)),r.sections!=null?new hr(r,t):new ot(r,t)}he.fromSourceMap=function(e,t){return ot.fromSourceMap(e,t)};he.prototype._version=3;he.prototype.__generatedMappings=null;Object.defineProperty(he.prototype,"_generatedMappings",{configurable:!0,enumerable:!0,get:function(){return this.__generatedMappings||this._parseMappings(this._mappings,this.sourceRoot),this.__generatedMappings}});he.prototype.__originalMappings=null;Object.defineProperty(he.prototype,"_originalMappings",{configurable:!0,enumerable:!0,get:function(){return this.__originalMappings||this._parseMappings(this._mappings,this.sourceRoot),this.__originalMappings}});he.prototype._charIsMappingSeparator=function(t,r){var n=t.charAt(r);return n===";"||n===","};he.prototype._parseMappings=function(t,r){throw new Error("Subclasses must implement _parseMappings")};he.GENERATED_ORDER=1;he.ORIGINAL_ORDER=2;he.GREATEST_LOWER_BOUND=1;he.LEAST_UPPER_BOUND=2;he.prototype.eachMapping=function(t,r,n){var o=r||null,i=n||he.GENERATED_ORDER,s;switch(i){case he.GENERATED_ORDER:s=this._generatedMappings;break;case he.ORIGINAL_ORDER:s=this._originalMappings;break;default:throw new Error("Unknown order of iteration.")}for(var a=this.sourceRoot,c=t.bind(o),l=this._names,A=this._sources,u=this._sourceMapURL,d=0,m=s.length;d<m;d++){var g=s[d],h=g.source===null?null:A.at(g.source);h!==null&&(h=D.computeSourceURL(a,h,u)),c({source:h,generatedLine:g.generatedLine,generatedColumn:g.generatedColumn,originalLine:g.originalLine,originalColumn:g.originalColumn,name:g.name===null?null:l.at(g.name)})}};he.prototype.allGeneratedPositionsFor=function(t){var r=D.getArg(t,"line"),n={source:D.getArg(t,"source"),originalLine:r,originalColumn:D.getArg(t,"column",0)};if(n.source=this._findSourceIndex(n.source),n.source<0)return[];var o=[],i=this._findMapping(n,this._originalMappings,"originalLine","originalColumn",D.compareByOriginalPositions,Lu.LEAST_UPPER_BOUND);if(i>=0){var s=this._originalMappings[i];if(t.column===void 0)for(var a=s.originalLine;s&&s.originalLine===a;)o.push({line:D.getArg(s,"generatedLine",null),column:D.getArg(s,"generatedColumn",null),lastColumn:D.getArg(s,"lastGeneratedColumn",null)}),s=this._originalMappings[++i];else for(var c=s.originalColumn;s&&s.originalLine===r&&s.originalColumn==c;)o.push({line:D.getArg(s,"generatedLine",null),column:D.getArg(s,"generatedColumn",null),lastColumn:D.getArg(s,"lastGeneratedColumn",null)}),s=this._originalMappings[++i]}return o};ic.SourceMapConsumer=he;function ot(e,t){var r=e;typeof e=="string"&&(r=D.parseSourceMapInput(e));var n=D.getArg(r,"version"),o=D.getArg(r,"sources"),i=D.getArg(r,"names",[]),s=D.getArg(r,"sourceRoot",null),a=D.getArg(r,"sourcesContent",null),c=D.getArg(r,"mappings"),l=D.getArg(r,"file",null);if(n!=this._version)throw new Error("Unsupported version: "+n);s&&(s=D.normalize(s)),o=o.map(String).map(D.normalize).map(function(A){return s&&D.isAbsolute(s)&&D.isAbsolute(A)?D.relative(s,A):A}),this._names=ei.fromArray(i.map(String),!0),this._sources=ei.fromArray(o,!0),this._absoluteSources=this._sources.toArray().map(function(A){return D.computeSourceURL(s,A,t)}),this.sourceRoot=s,this.sourcesContent=a,this._mappings=c,this._sourceMapURL=t,this.file=l}ot.prototype=Object.create(he.prototype);ot.prototype.consumer=he;ot.prototype._findSourceIndex=function(e){var t=e;if(this.sourceRoot!=null&&(t=D.relative(this.sourceRoot,t)),this._sources.has(t))return this._sources.indexOf(t);var r;for(r=0;r<this._absoluteSources.length;++r)if(this._absoluteSources[r]==e)return r;return-1};ot.fromSourceMap=function(t,r){var n=Object.create(ot.prototype),o=n._names=ei.fromArray(t._names.toArray(),!0),i=n._sources=ei.fromArray(t._sources.toArray(),!0);n.sourceRoot=t._sourceRoot,n.sourcesContent=t._generateSourcesContent(n._sources.toArray(),n.sourceRoot),n.file=t._file,n._sourceMapURL=r,n._absoluteSources=n._sources.toArray().map(function(m){return D.computeSourceURL(n.sourceRoot,m,r)});for(var s=t._mappings.toArray().slice(),a=n.__generatedMappings=[],c=n.__originalMappings=[],l=0,A=s.length;l<A;l++){var u=s[l],d=new rE;d.generatedLine=u.generatedLine,d.generatedColumn=u.generatedColumn,u.source&&(d.source=i.indexOf(u.source),d.originalLine=u.originalLine,d.originalColumn=u.originalColumn,u.name&&(d.name=o.indexOf(u.name)),c.push(d)),a.push(d)}return ji(n.__originalMappings,D.compareByOriginalPositions),n};ot.prototype._version=3;Object.defineProperty(ot.prototype,"sources",{get:function(){return this._absoluteSources.slice()}});function rE(){this.generatedLine=0,this.generatedColumn=0,this.source=null,this.originalLine=null,this.originalColumn=null,this.name=null}var Nu=D.compareByGeneratedPositionsDeflatedNoLine;function tE(e,t){let r=e.length,n=e.length-t;if(!(n<=1))if(n==2){let o=e[t],i=e[t+1];Nu(o,i)>0&&(e[t]=i,e[t+1]=o)}else if(n<20)for(let o=t;o<r;o++)for(let i=o;i>t;i--){let s=e[i-1],a=e[i];if(Nu(s,a)<=0)break;e[i-1]=a,e[i]=s}else ji(e,Nu,t)}ot.prototype._parseMappings=function(t,r){var n=1,o=0,i=0,s=0,a=0,c=0,l=t.length,A=0,u={},d={},m=[],g=[],h,I,C,x,y;let b=0;for(;A<l;)if(t.charAt(A)===";")n++,A++,o=0,tE(g,b),b=g.length;else if(t.charAt(A)===",")A++;else{for(h=new rE,h.generatedLine=n,x=A;x<l&&!this._charIsMappingSeparator(t,x);x++);for(I=t.slice(A,x),C=[];A<x;)ev.decode(t,A,d),y=d.value,A=d.rest,C.push(y);if(C.length===2)throw new Error("Found a source, but no line and column");if(C.length===3)throw new Error("Found a source and line, but no column");if(h.generatedColumn=o+C[0],o=h.generatedColumn,C.length>1&&(h.source=a+C[1],a+=C[1],h.originalLine=i+C[2],i=h.originalLine,h.originalLine+=1,h.originalColumn=s+C[3],s=h.originalColumn,C.length>4&&(h.name=c+C[4],c+=C[4])),g.push(h),typeof h.originalLine=="number"){let v=h.source;for(;m.length<=v;)m.push(null);m[v]===null&&(m[v]=[]),m[v].push(h)}}tE(g,b),this.__generatedMappings=g;for(var S=0;S<m.length;S++)m[S]!=null&&ji(m[S],D.compareByOriginalPositionsNoSource);this.__originalMappings=[].concat(...m)};ot.prototype._findMapping=function(t,r,n,o,i,s){if(t[n]<=0)throw new TypeError("Line must be greater than or equal to 1, got "+t[n]);if(t[o]<0)throw new TypeError("Column must be greater than or equal to 0, got "+t[o]);return Lu.search(t,r,i,s)};ot.prototype.computeColumnSpans=function(){for(var t=0;t<this._generatedMappings.length;++t){var r=this._generatedMappings[t];if(t+1<this._generatedMappings.length){var n=this._generatedMappings[t+1];if(r.generatedLine===n.generatedLine){r.lastGeneratedColumn=n.generatedColumn-1;continue}}r.lastGeneratedColumn=1/0}};ot.prototype.originalPositionFor=function(t){var r={generatedLine:D.getArg(t,"line"),generatedColumn:D.getArg(t,"column")},n=this._findMapping(r,this._generatedMappings,"generatedLine","generatedColumn",D.compareByGeneratedPositionsDeflated,D.getArg(t,"bias",he.GREATEST_LOWER_BOUND));if(n>=0){var o=this._generatedMappings[n];if(o.generatedLine===r.generatedLine){var i=D.getArg(o,"source",null);i!==null&&(i=this._sources.at(i),i=D.computeSourceURL(this.sourceRoot,i,this._sourceMapURL));var s=D.getArg(o,"name",null);return s!==null&&(s=this._names.at(s)),{source:i,line:D.getArg(o,"originalLine",null),column:D.getArg(o,"originalColumn",null),name:s}}}return{source:null,line:null,column:null,name:null}};ot.prototype.hasContentsOfAllSources=function(){return this.sourcesContent?this.sourcesContent.length>=this._sources.size()&&!this.sourcesContent.some(function(t){return t==null}):!1};ot.prototype.sourceContentFor=function(t,r){if(!this.sourcesContent)return null;var n=this._findSourceIndex(t);if(n>=0)return this.sourcesContent[n];var o=t;this.sourceRoot!=null&&(o=D.relative(this.sourceRoot,o));var i;if(this.sourceRoot!=null&&(i=D.urlParse(this.sourceRoot))){var s=o.replace(/^file:\/\//,"");if(i.scheme=="file"&&this._sources.has(s))return this.sourcesContent[this._sources.indexOf(s)];if((!i.path||i.path=="/")&&this._sources.has("/"+o))return this.sourcesContent[this._sources.indexOf("/"+o)]}if(r)return null;throw new Error('"'+o+'" is not in the 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Error("Support for url field in sections not implemented.");var a=D.getArg(s,"offset"),c=D.getArg(a,"line"),l=D.getArg(a,"column");if(c<i.line||c===i.line&&l<i.column)throw new Error("Section offsets must be ordered and non-overlapping.");return i=a,{generatedOffset:{generatedLine:c+1,generatedColumn:l+1},consumer:new he(D.getArg(s,"map"),t)}})}hr.prototype=Object.create(he.prototype);hr.prototype.constructor=he;hr.prototype._version=3;Object.defineProperty(hr.prototype,"sources",{get:function(){for(var e=[],t=0;t<this._sections.length;t++)for(var r=0;r<this._sections[t].consumer.sources.length;r++)e.push(this._sections[t].consumer.sources[r]);return e}});hr.prototype.originalPositionFor=function(t){var r={generatedLine:D.getArg(t,"line"),generatedColumn:D.getArg(t,"column")},n=Lu.search(r,this._sections,function(i,s){var a=i.generatedLine-s.generatedOffset.generatedLine;return a||i.generatedColumn-s.generatedOffset.generatedColumn}),o=this._sections[n];return o?o.consumer.originalPositionFor({line:r.generatedLine-(o.generatedOffset.generatedLine-1),column:r.generatedColumn-(o.generatedOffset.generatedLine===r.generatedLine?o.generatedOffset.generatedColumn-1:0),bias:t.bias}):{source:null,line:null,column:null,name:null}};hr.prototype.hasContentsOfAllSources=function(){return this._sections.every(function(t){return t.consumer.hasContentsOfAllSources()})};hr.prototype.sourceContentFor=function(t,r){for(var n=0;n<this._sections.length;n++){var o=this._sections[n],i=o.consumer.sourceContentFor(t,!0);if(i||i==="")return i}if(r)return null;throw new Error('"'+t+'" is not in the SourceMap.')};hr.prototype.generatedPositionFor=function(t){for(var r=0;r<this._sections.length;r++){var n=this._sections[r];if(n.consumer._findSourceIndex(D.getArg(t,"source"))!==-1){var o=n.consumer.generatedPositionFor(t);if(o){var 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 UniProt/Swiss-Prot|P01590|IL2RA_MOUSE      MEPRLLMLGFLSLTIVPSCRAELCLYDPPEVPNA----------TFKALSYK----NGTI
 UniProt/Swiss-Prot|P41690|IL2RA_FELCA      MEPSLLLWGILTFVVVHGHVTELCDENPPDIQHA----------TFKALTYK----TGTM
@@ -41,7 +41,7 @@ UniProt/Swiss-Prot|Q8BZM1|GLMN_MOUSE       PLPLRSLLFLQLPLLGVGLNP----------------
 UniProt/Swiss-Prot|P36835|IL2_CAPHI        -----------LLGVGLNPKFLTP------------------------------------
 UniProt/Swiss-Prot|Q7JFM4|IL2_AOTVO        MLKPPLPLRSLLFLQLPLLGVGLNPKFLTPSGNEDIGGKPGTGGDFFLTSTPAGTLDVST
 UniProt/Swiss-Prot|Q29416|IL2_CANFA        --------------LFLQLSLLG-------------------------------------
-`,hB=`CLUSTAL O(1.2.4) multiple sequence alignment
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@@ -57,23 +57,23 @@ sp|P13786|HBAZ_CAPHI      SKVVAAVGDAVKSIDNVTSALSKLSELHAYVLRVDPVNFKFLSHCLLVTLASHF
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 sp|P01942|HBA_MOUSE       AVHASLDKFLASVSTVLTSKYR	142
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Al="https://www.ebi.ac.uk/Tools/services/rest",Ik={clustalo:{params:{email:"colin.diesh@gmail.com"},msaResult:"aln-clustal_num",treeResult:"phylotree"},muscle:{params:{email:"colin.diesh@gmail.com",format:"clw",tree:"tree1"},msaResult:"fa",treeResult:"phylotree"},kalign:{params:{email:"colin.diesh@gmail.com",stype:"protein"},msaResult:"fa",treeResult:"phylotree"},mafft:{params:{email:"colin.diesh@gmail.com",stype:"protein"},msaResult:"fa",treeResult:"phylotree"}};async function xk({onProgress:e,jobId:t,algorithm:r}){for(;;){for(let o=0;o<10;o++)await Zs(1e3),e(`Re-checking MSA status in... ${10-o}`);let n=await fr(`${Al}/${r}/status/${t}`);if(n==="FINISHED")break;if(n.includes("FAILURE"))throw new Error(`Failed to run: jobId ${t}`)}}async function LS({algorithm:e,sequence:t,onProgress:r}){let n=Ik[e];if(!n)throw new Error(`unknown algorithm: ${e}`);r(`Launching ${e} MSA...`);let o=await fr(`${Al}/${e}/run`,{method:"POST",body:new URLSearchParams({...n.params,sequence:t})});return await 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XS(e,t){let r=e.toUpperCase(),n=t.toUpperCase();return Lk[r]?.[n]??-4}var Fk=-10,Rk=-.5;function Pk(e,t,r=Fk,n=Rk){let o=e.length,i=t.length,s=[],a=[],c=[];for(let E=0;E<=o;E++){s[E]=[],a[E]=[],c[E]=[];for(let C=0;C<=i;C++)s[E][C]=-1/0,a[E][C]=-1/0,c[E][C]=-1/0}s[0][0]=0;for(let E=1;E<=o;E++)a[E][0]=r+(E-1)*n;for(let E=1;E<=i;E++)c[0][E]=r+(E-1)*n;for(let E=1;E<=o;E++)for(let C=1;C<=i;C++){let x=XS(e[E-1],t[C-1]);s[E][C]=Math.max(s[E-1][C-1],a[E-1][C-1],c[E-1][C-1])+x,a[E][C]=Math.max(s[E-1][C]+r,a[E-1][C]+n),c[E][C]=Math.max(s[E][C-1]+r,c[E][C-1]+n)}let l="",A="",u=o,f=i,m=[s[o][i],a[o][i],c[o][i]],g=Math.max(...m),h=g===s[o][i]?"M":g===a[o][i]?"Ix":"Iy";for(;u>0||f>0;)if(h==="M"&&u>0&&f>0){l=e[u-1]+l,A=t[f-1]+A;let E=XS(e[u-1],t[f-1]),C=s[u-1][f-1],x=a[u-1][f-1];s[u][f]===C+E?h="M":s[u][f]===x+E?h="Ix":h="Iy",u--,f--}else if(h==="Ix"&&u>0)l=e[u-1]+l,A="-"+A,h=a[u][f]===s[u-1][f]+r?"M":"Ix",u--;else if(f>0)l="-"+l,A=t[f-1]+A,h=c[u][f]===s[u][f-1]+r?"M":"Iy",f--;else break;return{alignedSeq1:l,alignedSeq2:A,score:g}}function Gk(e,t){let r="";for(let n=0;n<e.length;n++){let o=e[n],i=t[n];o==="-"||i==="-"?r+=" ":o.toUpperCase()===i.toUpperCase()?r+="|":r+=" "}return r}function ZS(e,t){let{alignedSeq1:r,alignedSeq2:n}=Pk(e,t);return{consensus:Gk(r,n),alns:[{id:"msa",seq:r},{id:"structure",seq:n}]}}function eQ(e){let t=e.alns[0].seq,r=e.alns[1].seq;if(t.length!==r.length)throw new Error("Aligned sequences must have same length");let n=0,o=0,i=new Map,s=new Map;for(let a=0;a<t.length;a++){let c=t[a],l=r[a];c!=="-"&&l!=="-"?(i.set(n,o),s.set(o,n),n++,o++):c==="-"?o++:n++}return{seq1ToSeq2:i,seq2ToSeq1:s}}var Jk=(0,sQ.lazy)(()=>Promise.resolve().then(()=>(iQ(),oQ)));function Uk(e){let{mouseCol:t,connectedProteinViews:r}=e;if(r.length!==0)for(let n of r){let o=n.proteinView?.structures?.[n.structureIdx];if(!o)continue;if(t===void 0){o.clearHighlightFromExternal?.();continue}let i=e.getSequenceByRowName(n.msaRowName);if(!i)continue;let s=el(i,t);if(s===void 0){o.clearHighlightFromExternal?.();continue}let a=n.msaToStructure[s];a===void 0?o.clearHighlightFromExternal?.():o.highlightFromExternal?.(a)}}function bd(){return ee.types.compose(aQ.BaseViewModel,xd(),ee.types.model("MsaView",{connectedViewId:ee.types.maybe(ee.types.string),connectedFeature:ee.types.frozen(),connectedHighlights:ee.types.array(ee.types.model({refName:ee.types.string,start:ee.types.number,end:ee.types.number})),blastParams:ee.types.frozen(),querySeqName:"QUERY",uniprotId:ee.types.maybe(ee.types.string),zoomToBaseLevel:!1,init:ee.types.frozen(),connectedStructures:ee.types.array(ee.types.frozen()),dataStoreId:ee.types.maybe(ee.types.string),mafRegion:ee.types.frozen()})).volatile(()=>({rid:void 0,progress:"",error:void 0,loadingStoredData:!1})).views(e=>({getRowByName(t){return e.rows.find(r=>r[0]===t)},getSequenceByRowName(t){return e.rows.find(r=>r[0]===t)?.[1]}})).views(e=>({get transcriptToMsaMap(){return e.connectedFeature?Sh(e.connectedFeature):void 0},get processing(){return!!e.progress},get connectedView(){let{views:t}=(0,_n.getSession)(e);return t.find(r=>r.id===e.connectedViewId)},get connectedProteinViews(){let{views:t}=(0,_n.getSession)(e);return e.connectedStructures.map(r=>{let n=t.find(o=>o.id===r.proteinViewId);return n?{...r,proteinView:n}:void 0}).filter(r=>!!r)}})).views(e=>({get structureHoverCol(){for(let t of e.connectedProteinViews){let n=t.proteinView?.structures?.[t.structureIdx]?.hoverPosition?.structureSeqPos;if(n!==void 0){let o=t.structureToMsa[n];if(o!==void 0){let i=e.getSequenceByRowName(t.msaRowName);if(i){let s=VS(i,o);if(s!==void 0)return e.globalColToVisibleCol(s)}}}}}})).views(e=>({get mouseCol2(){let t=e.structureHoverCol;return t!==void 0?t:jS({model:e})},get clickCol2(){}})).actions(e=>({setZoomToBaseLevel(t){e.zoomToBaseLevel=t},setError(t){e.error=t},setProgress(t){e.progress=t},setRid(t){e.rid=t},setConnectedHighlights(t){e.connectedHighlights=(0,ee.cast)(t)},addToConnectedHighlights(t){e.connectedHighlights.push(t)},clearConnectedHighlights(){e.connectedHighlights=(0,ee.cast)([])},setBlastParams(t){e.blastParams=t},setInit(t){e.init=t},setQuerySeqName(t){e.querySeqName=t},setUniprotId(t){e.uniprotId=t},setDataStoreId(t){e.dataStoreId=t},setMafRegion(t){e.mafRegion=t},setLoadingStoredData(t){e.loadingStoredData=t},handleMsaClick(t){let{connectedView:r,zoomToBaseLevel:n}=e,{assemblyManager:o}=(0,_n.getSession)(e),i=tl({model:e,coord:t});if(!(!i||!r))if(n)r.navTo(i);else{let s=o.get(r.assemblyNames[0])?.getCanonicalRefName(i.refName)??i.refName;r.centerAt(i.start,s)}},connectToStructure(t,r,n){let o=n??e.querySeqName,i=e.getSequenceByRowName(o);if(!i)throw new Error(`MSA row "${o}" not found`);let s=i.replaceAll("-",""),{views:a}=(0,_n.getSession)(e),c=a.find(h=>h.id===t);if(!c)throw new Error(`ProteinView "${t}" not found`);let l=c.structures?.[r];if(!l)throw new Error(`Structure at index ${r} not found`);let A=l.structureSequences?.[0];if(!A)throw new Error("Structure sequence not available");let u=ZS(s,A),{seq1ToSeq2:f,seq2ToSeq1:m}=eQ(u),g={proteinViewId:t,structureIdx:r,msaRowName:o,msaToStructure:wd(f),structureToMsa:wd(m)};e.connectedStructures.push(g)},disconnectFromStructure(t,r){let n=e.connectedStructures.findIndex(o=>o.proteinViewId===t&&o.structureIdx===r);n!==-1&&e.connectedStructures.splice(n,1)},disconnectAllStructures(){e.connectedStructures.clear()}})).actions(e=>{let t=e.setMouseClickPos.bind(e);return{setMouseClickPos(r,n){t(r,n),r!==void 0&&e.handleMsaClick(r)}}}).views(e=>({extraViewMenuItems(){return[{label:"Zoom to base level on click?",checked:e.zoomToBaseLevel,type:"checkbox",onClick:()=>{e.setZoomToBaseLevel(!e.zoomToBaseLevel)}},{label:"Connect to protein structure...",onClick:()=>{(0,_n.getSession)(e).queueDialog(t=>[Jk,{model:e,handleClose:t}])}},...e.connectedStructures.length>0?[{label:"Disconnect from protein structures",onClick:()=>{e.disconnectAllStructures()}}]:[]]}})).actions(e=>({afterCreate(){$S().catch(t=>{console.error("Failed to cleanup old MSA data:",t)}),(0,ee.addDisposer)(e,(0,sn.autorun)(async()=>{let{dataStoreId:t,rows:r}=e;if(t&&r.length===0)try{e.setLoadingStoredData(!0);let n=await zS(t);n&&(n.msa&&e.setMSA(n.msa),n.tree&&e.setTree(n.tree))}catch(n){console.error("Failed to load MSA data from IndexedDB:",n)}finally{e.setLoadingStoredData(!1)}})),(0,ee.addDisposer)(e,(0,sn.autorun)(async()=>{let{rows:t,dataStoreId:r}=e;if(t.length>0&&!r){if(!!(e.msaFilehandle??e.treeFilehandle))return;let o=e.data.msa,i=e.data.tree;if(o||i)try{let s=WS();await KS(s,{msa:o,tree:i,treeMetadata:e.data.treeMetadata})&&e.setDataStoreId(s)}catch(s){console.error("Failed to store MSA data to IndexedDB:",s)}}})),(0,ee.addDisposer)(e,(0,sn.autorun)(async()=>{if(e.blastParams)try{e.setProgress("Submitting query"),e.setError(void 0);let t=await JS({self:e});e.setData(t),e.setBlastParams(void 0)}catch(t){e.setError(t),console.error(t)}finally{e.setProgress("")}})),(0,ee.addDisposer)(e,(0,sn.autorun)(async()=>{let{init:t}=e;if(t)try{e.setError(void 0);let{msaData:r,msaUrl:n,treeData:o,treeUrl:i,querySeqName:s}=t;if(n){let a=YS(n);a&&(e.setUniprotId(a),e.setQuerySeqName("query"))}if(s&&e.setQuerySeqName(s),r)e.setMSA(r);else if(n){let a=await fetch(n);if(!a.ok)throw new Error(`Failed to fetch MSA: ${a.status}`);let c=await a.text();e.setMSA(c)}if(o)e.setTree(o);else if(i){let a=await fetch(i);if(!a.ok)throw new Error(`Failed to fetch tree: ${a.status}`);let c=await a.text();e.setTree(c)}e.setInit(void 0)}catch(r){e.setError(r),console.error(r)}})),(0,ee.addDisposer)(e,(0,sn.autorun)(()=>{let{mouseCol:t,mouseClickCol:r}=e,n=t===void 0?void 0:tl({model:e,coord:t}),o=r===void 0?void 0:tl({model:e,coord:r});e.setConnectedHighlights([n,o].filter(i=>!!i))})),(0,ee.addDisposer)(e,(0,sn.autorun)(()=>{Uk(e)})),(0,ee.addDisposer)(e,(0,sn.autorun)(()=>{let{views:t}=(0,_n.getSession)(e),{connectedViewId:r,uniprotId:n,rows:o,connectedStructures:i}=e;if(!(!n||o.length===0))for(let s of t){let a=s;if(!(a.type!=="ProteinView"||!a.structures))for(let c=0;c<a.structures.length;c++){let l=a.structures[c];if(!(l.connectedViewId!==r||l.uniprotId!==n||i.some(u=>u.proteinViewId===a.id&&u.structureIdx===c))&&l.structureSequences?.[0])try{e.connectToStructure(a.id,c)}catch(u){console.error("Failed to auto-connect to ProteinView:",u)}}}})),(0,ee.addDisposer)(e,(0,sn.autorun)(()=>{let{views:t}=(0,_n.getSession)(e),{connectedViewId:r,transcriptToMsaMap:n,querySeqName:o}=e;if(!r||!n)return;let i=[];for(let a of t){let c=a;if(!(c.type!=="ProteinView"||!c.structures))for(let l of c.structures){if(l.connectedViewId!==r)continue;let A=l.hoverGenomeHighlights;if(!A||A.length===0)continue;let{g2p:u}=n;for(let f of A)for(let m=f.start;m<f.end;m++){let g=u[m];if(g!==void 0){let h=e.seqPosToGlobalCol(o,g);i.includes(h)||i.push(h)}}}}let s=i.map(a=>e.globalColToVisibleCol(a)).filter(a=>a!==void 0);e.setHighlightedColumns(s.length>0?s:void 0)}))}}))}var zk=(0,EQ.lazy)(()=>Promise.resolve().then(()=>(CQ(),hQ)));function vd(e){e.addViewType(()=>new IQ.default({name:"MsaView",stateModel:bd(),ReactComponent:zk}))}var xQ="2.2.8";var ol=class extends yQ.default{constructor(){super(...arguments);this.name="MsaViewPlugin";this.version=xQ}install(r){vd(r),LA(r),FA(r),ml(r),kl(r)}configure(r){(0,wQ.isAbstractMenuManager)(r.rootModel)&&r.rootModel.appendToSubMenu(["Add"],{label:"Multiple sequence alignment view",icon:em,onClick:n=>{n.addView("MsaView",{})}})}rootConfigurationSchema(r){return{msa:(0,Td.ConfigurationSchema)("MSA",{datasets:Dd.types.maybe(Dd.types.array((0,Td.ConfigurationSchema)("MSAEntry",{datasetId:{type:"string",defaultValue:""},description:{type:"string",defaultValue:""},name:{type:"string",defaultValue:""},adapter:r.pluggableConfigSchemaType("adapter")})))})}}};return FQ($k);})();
+`),onProgress:C=>{e.setProgress(C)}}),I=JSON.stringify(m);return await cp({proteinSequence:c,blastDatabase:r,blastProgram:n,msaAlgorithm:o,msa:h.msa,tree:h.tree,treeMetadata:I,rid:A,geneId:s?.get("parentId"),transcriptId:s?.id(),transcriptName:s?.get("name")??s?.get("id"),geneName:s?.get("gene_name")??s?.get("parentId")}),{...h,treeMetadata:I}}function Mk(e,t){let r={},n=e.taxid?t.get(e.taxid):void 0;return n?.sciname&&(r["Scientific name"]=n.sciname),n?.commonName&&(r["Common name"]=n.commonName),e.accession&&(r.Accession=e.accession),e.id&&(r.ID=e.id),e.title&&(r.Description=e.title),r}function ul(e,t){if(t<0||t>=e.length)return;let r=0;for(let n=0;n<t;n++)e[n]!=="-"&&r++;if(e[t]!=="-")return r}function GS(e,t){let r=0;for(let n=0;n<e.length;n++)if(e[n]!=="-"){if(r===t)return n;r++}}function _d(e){return Object.fromEntries(e)}function xs({model:e,coord:t}){let{querySeqName:r,transcriptToMsaMap:n,mafRegion:o}=e,s=e.rows.find(c=>c[0]===r)?.[1];if(!s)return;let a=ul(s,t);if(a!==void 0){if(o){let c=o.start+a;return c>=o.end?void 0:{refName:o.refName,start:c,end:c+1}}if(n){let{refName:c,p2g:l}=n,A=l[a],u=l[a+1];return A!==void 0&&u!==void 0?{refName:c,start:Math.min(A,u),end:Math.max(A,u)}:void 0}}}Di();var vk="jbrowse-msaview-data",Tk=1,ys="msa-data";async function Dd(){return Rn(vk,Tk,{upgrade(e){e.objectStoreNames.contains(ys)||e.createObjectStore(ys,{keyPath:"id"}).createIndex("timestamp","timestamp",{unique:!1})}})}function JS(){return`msa-${Date.now()}-${Math.random().toString(36).slice(2,11)}`}async function HS(e,t){try{let r=await Dd(),n={id:e,msa:t.msa,tree:t.tree,treeMetadata:t.treeMetadata,timestamp:Date.now()};return await r.put(ys,n),!0}catch(r){return console.warn("Failed to store MSA data:",r),!1}}async function US(e){try{let r=await(await Dd()).get(ys,e);return r?{msa:r.msa,tree:r.tree,treeMetadata:r.treeMetadata}:void 0}catch(t){console.warn("Failed to retrieve MSA data:",t);return}}async function qS(e=10080*60*1e3){try{let t=await Dd(),r=Date.now()-e,i=await t.transaction(ys,"readwrite").store.index("timestamp").openCursor(IDBKeyRange.upperBound(r)),s=0;for(;i;)await i.delete(),s++,i=await i.continue();return s}catch(t){return console.warn("Failed to cleanup old MSA data:",t),0}}function YS(e){return typeof e=="object"&&e!==null&&"hoverFeature"in e&&"hoverPosition"in e}function jS(e){return/AF-([A-Z0-9]+)-F\d+/.exec(e)?.[1]}function VS(e){let{dataStoreId:t,rows:r}=e;t&&r.length===0&&(async()=>{try{e.setLoadingStoredData(!0);let n=await US(t);n&&(n.msa&&e.setMSA(n.msa),n.tree&&e.setTree(n.tree))}catch(n){console.error("Failed to load MSA data from IndexedDB:",n)}finally{e.setLoadingStoredData(!1)}})()}function WS(e){let{rows:t,dataStoreId:r}=e;if(t.length>0&&!r){if(!!(e.msaFilehandle??e.treeFilehandle))return;let o=e.data.msa,i=e.data.tree;(o||i)&&(async()=>{try{let s=JS();await HS(s,{msa:o,tree:i,treeMetadata:e.data.treeMetadata})&&e.setDataStoreId(s)}catch(s){console.error("Failed to store MSA data to 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iQ(e,t){let r=e.toUpperCase(),n=t.toUpperCase();return oQ[r]?.[n]??-4}var Dk=-10,kk=-.5;function Nk(e,t,r=Dk,n=kk){let o=e.length,i=t.length,s=[],a=[],c=[];for(let I=0;I<=o;I++){s[I]=[],a[I]=[],c[I]=[];for(let C=0;C<=i;C++)s[I][C]=-1/0,a[I][C]=-1/0,c[I][C]=-1/0}s[0][0]=0;for(let I=1;I<=o;I++)a[I][0]=r+(I-1)*n;for(let I=1;I<=i;I++)c[0][I]=r+(I-1)*n;for(let I=1;I<=o;I++)for(let C=1;C<=i;C++){let x=iQ(e[I-1],t[C-1]);s[I][C]=Math.max(s[I-1][C-1],a[I-1][C-1],c[I-1][C-1])+x,a[I][C]=Math.max(s[I-1][C]+r,a[I-1][C]+n),c[I][C]=Math.max(s[I][C-1]+r,c[I][C-1]+n)}let l="",A="",u=o,d=i,m=[s[o][i],a[o][i],c[o][i]],g=Math.max(...m),h=g===s[o][i]?"M":g===a[o][i]?"Ix":"Iy";for(;u>0||d>0;)if(h==="M"&&u>0&&d>0){l=e[u-1]+l,A=t[d-1]+A;let I=iQ(e[u-1],t[d-1]),C=s[u-1][d-1],x=a[u-1][d-1];s[u][d]===C+I?h="M":s[u][d]===x+I?h="Ix":h="Iy",u--,d--}else if(h==="Ix"&&u>0)l=e[u-1]+l,A="-"+A,h=a[u][d]===s[u-1][d]+r?"M":"Ix",u--;else if(d>0)l="-"+l,A=t[d-1]+A,h=c[u][d]===s[u][d-1]+r?"M":"Iy",d--;else break;return{alignedSeq1:l,alignedSeq2:A,score:g}}function Lk(e,t){let r="";for(let n=0;n<e.length;n++){let o=e[n],i=t[n];o==="-"||i==="-"?r+=" ":o.toUpperCase()===i.toUpperCase()?r+="|":r+=" "}return r}function sQ(e,t){let{alignedSeq1:r,alignedSeq2:n}=Nk(e,t);return{consensus:Lk(r,n),alns:[{id:"msa",seq:r},{id:"structure",seq:n}]}}function aQ(e){let t=e.alns[0].seq,r=e.alns[1].seq;if(t.length!==r.length)throw new Error("Aligned sequences must have same length");let n=0,o=0,i=new Map,s=new Map;for(let a=0;a<t.length;a++){let c=t[a],l=r[a];c!=="-"&&l!=="-"?(i.set(n,o),s.set(o,n),n++,o++):c==="-"?o++:n++}return{seq1ToSeq2:i,seq2ToSeq1:s}}var Pk=(0,dQ.lazy)(()=>Promise.resolve().then(()=>(fQ(),uQ)));function Nd(){return Ie.types.compose(mQ.BaseViewModel,ll(),Ie.types.model("MsaView",{connectedViewId:Ie.types.maybe(Ie.types.string),connectedFeature:Ie.types.frozen(),connectedHighlights:Ie.types.array(Ie.types.model({refName:Ie.types.string,start:Ie.types.number,end:Ie.types.number})),blastParams:Ie.types.frozen(),querySeqName:"QUERY",uniprotId:Ie.types.maybe(Ie.types.string),zoomToBaseLevel:!1,init:Ie.types.frozen(),connectedStructures:Ie.types.array(Ie.types.frozen()),dataStoreId:Ie.types.maybe(Ie.types.string),mafRegion:Ie.types.frozen()})).volatile(()=>({rid:void 0,progress:"",error:void 0,loadingStoredData:!1})).views(e=>({getRowByName(t){return e.rows.find(r=>r[0]===t)},getSequenceByRowName(t){return e.rows.find(r=>r[0]===t)?.[1]}})).views(e=>({get transcriptToMsaMap(){return e.connectedFeature?Fh(e.connectedFeature):void 0},get processing(){return!!e.progress},get connectedView(){let{views:t}=(0,Ii.getSession)(e);return t.find(r=>r.id===e.connectedViewId)},get connectedProteinViews(){let{views:t}=(0,Ii.getSession)(e);return e.connectedStructures.map(r=>{let n=t.find(o=>o.id===r.proteinViewId);return n?{...r,proteinView:n}:void 0}).filter(r=>!!r)}})).views(e=>({get structureHoverCol(){for(let t of e.connectedProteinViews){let n=t.proteinView?.structures?.[t.structureIdx]?.hoverPosition?.structureSeqPos;if(n!==void 0){let o=t.structureToMsa[n];if(o!==void 0){let i=e.getSequenceByRowName(t.msaRowName);if(i){let s=GS(i,o);if(s!==void 0)return e.globalColToVisibleCol(s)}}}}}})).views(e=>({get mouseCol2(){let t=e.structureHoverCol;return t!==void 0?t:nQ({model:e})},get clickCol2(){}})).actions(e=>({setZoomToBaseLevel(t){e.zoomToBaseLevel=t},setError(t){e.error=t},setProgress(t){e.progress=t},setRid(t){e.rid=t},setConnectedHighlights(t){e.connectedHighlights=(0,Ie.cast)(t)},addToConnectedHighlights(t){e.connectedHighlights.push(t)},clearConnectedHighlights(){e.connectedHighlights=(0,Ie.cast)([])},setBlastParams(t){e.blastParams=t},setInit(t){e.init=t},setQuerySeqName(t){e.querySeqName=t},setUniprotId(t){e.uniprotId=t},setDataStoreId(t){e.dataStoreId=t},setMafRegion(t){e.mafRegion=t},setLoadingStoredData(t){e.loadingStoredData=t},handleMsaClick(t){let{connectedView:r,zoomToBaseLevel:n}=e,{assemblyManager:o}=(0,Ii.getSession)(e),i=xs({model:e,coord:t});if(!(!i||!r))if(n)r.navTo(i);else{let s=o.get(r.assemblyNames[0])?.getCanonicalRefName(i.refName)??i.refName;r.centerAt(i.start,s)}},connectToStructure(t,r,n){let o=n??e.querySeqName,i=e.getSequenceByRowName(o);if(!i)throw new Error(`MSA row "${o}" not found`);let s=i.replaceAll("-",""),{views:a}=(0,Ii.getSession)(e),c=a.find(h=>h.id===t);if(!c)throw new Error(`ProteinView "${t}" not found`);let l=c.structures?.[r];if(!l)throw new Error(`Structure at index ${r} not found`);let A=l.structureSequences?.[0];if(!A)throw new Error("Structure sequence not available");let u=sQ(s,A),{seq1ToSeq2:d,seq2ToSeq1:m}=aQ(u),g={proteinViewId:t,structureIdx:r,msaRowName:o,msaToStructure:_d(d),structureToMsa:_d(m)};e.connectedStructures.push(g)},disconnectFromStructure(t,r){let n=e.connectedStructures.findIndex(o=>o.proteinViewId===t&&o.structureIdx===r);n!==-1&&e.connectedStructures.splice(n,1)},disconnectAllStructures(){e.connectedStructures.clear()}})).actions(e=>{let t=e.setMouseClickPos.bind(e);return{setMouseClickPos(r,n){t(r,n),r!==void 0&&e.handleMsaClick(r)}}}).views(e=>({extraViewMenuItems(){return[{label:"Zoom to base level on click?",checked:e.zoomToBaseLevel,type:"checkbox",onClick:()=>{e.setZoomToBaseLevel(!e.zoomToBaseLevel)}},{label:"Connect to protein structure...",onClick:()=>{(0,Ii.getSession)(e).queueDialog(t=>[Pk,{model:e,handleClose:t}])}},...e.connectedStructures.length>0?[{label:"Disconnect from protein structures",onClick:()=>{e.disconnectAllStructures()}}]:[]]}})).actions(e=>({afterCreate(){tQ();for(let t of[VS,WS,zS,$S,KS,XS,ZS,eQ])(0,Ie.addDisposer)(e,(0,gQ.autorun)(()=>{t(e)}))}}))}var Yk=(0,QQ.lazy)(()=>Promise.resolve().then(()=>(SQ(),bQ)));function Pd(e){e.addViewType(()=>new MQ.default({name:"MsaView",stateModel:Nd(),ReactComponent:Yk}))}var vQ="2.2.11";var dl=class extends TQ.default{constructor(){super(...arguments);this.name="MsaViewPlugin";this.version=vQ;this.rootConfigurationSchema=r=>({msa:(0,Od.ConfigurationSchema)("MSA",{datasets:Gd.types.maybe(Gd.types.array((0,Od.ConfigurationSchema)("MSAEntry",{datasetId:{type:"string",defaultValue:""},description:{type:"string",defaultValue:""},name:{type:"string",defaultValue:""},adapter:r.pluggableConfigSchemaType("adapter")})))})})}install(r){Pd(r),qA(r),YA(r),wl(r),Hl(r)}configure(r){(0,_Q.isAbstractMenuManager)(r.rootModel)&&r.rootModel.appendToSubMenu(["Add"],{label:"Multiple sequence alignment view",icon:lm,onClick:n=>{n.addView("MsaView",{})}})}};return qQ(jk);})();
 /*! Bundled license information:
 use-sync-external-store/cjs/use-sync-external-store-shim.production.js:
@@ -97,9 +97,6 @@ react-is/cjs/react-is.production.min.js:
    * LICENSE file in the root directory of this source tree.
    *)
-dompurify/dist/purify.es.mjs:
-  (*! @license DOMPurify 3.3.1 | (c) Cure53 and other contributors | Released under the Apache license 2.0 and Mozilla Public License 2.0 | github.com/cure53/DOMPurify/blob/3.3.1/LICENSE *)
 escape-html/index.js:
   (*!
    * escape-html
@@ -108,5 +105,8 @@ escape-html/index.js:
    * Copyright(c) 2015 Tiancheng "Timothy" Gu
    * MIT Licensed
    *)
+dompurify/dist/purify.es.mjs:
+  (*! @license DOMPurify 3.3.3 | (c) Cure53 and other contributors | Released under the Apache license 2.0 and Mozilla Public License 2.0 | github.com/cure53/DOMPurify/blob/3.3.3/LICENSE *)
 */
 //# sourceMappingURL=jbrowse-plugin-msaview.umd.production.min.js.map