@sjcrh/proteinpaint-client 2.226.0 → 2.227.1
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/dist/2dmaf-75YAQQ3P.js +1362 -0
- package/dist/AggMatrixInput-KYDS23KP.js +402 -0
- package/dist/AggregateMatrix-XGGF6KBX.js +37 -0
- package/dist/AppHeader-CNY5RTJN.js +826 -0
- package/dist/BoxPlot-OQIJJO66.js +1247 -0
- package/dist/CorrelationVolcano-QN5D37V7.js +613 -0
- package/dist/CorrelationVolcano-QN5D37V7.js.map +7 -0
- package/dist/Cuminc-J6DONJTA.js +1217 -0
- package/dist/DE-XUBJUUBB.js +85 -0
- package/dist/DEinput-DCOPTSWO.js +483 -0
- package/dist/DEinput-DCOPTSWO.js.map +7 -0
- package/dist/DM-2UUXUJOC.js +86 -0
- package/dist/DifferentialAnalysis-U6ZPFHNM.js +236 -0
- package/dist/Disco-RR2NN66T.js +3445 -0
- package/dist/Disco.UI-MQ7WZQOP.js +239 -0
- package/dist/DmrPlot-MKAKFUJR.js +366 -0
- package/dist/GB-2X3ZRFXN.js +1388 -0
- package/dist/GB-2X3ZRFXN.js.map +7 -0
- package/dist/GSEA-DTIA4MNS.js +870 -0
- package/dist/GeneExpInput-4GM5MBBX.js +38 -0
- package/dist/Geomap-FF6DBN7M.js +80 -0
- package/dist/HicApp-LGXNL36X.js +2240 -0
- package/dist/IDCViewer-FQABJNUI.js +10810 -0
- package/dist/NumBinaryEditor-7NOHUH76.js +274 -0
- package/dist/NumBinaryEditor.unit.spec-SVE5SZYB.js +308 -0
- package/dist/NumContEditor-MSWCQUKL.js +100 -0
- package/dist/NumContEditor.unit.spec-UFPASWBH.js +160 -0
- package/dist/NumCustomBinEditor-DF24SO2N.js +29 -0
- package/dist/NumCustomBinEditor.unit.spec-N3S3ROBI.js +393 -0
- package/dist/NumDiscreteEditor-HL257XGY.js +165 -0
- package/dist/NumDiscreteEditor.unit.spec-6PTPX547.js +229 -0
- package/dist/NumRegularBinEditor-EWCKTXWY.js +29 -0
- package/dist/NumRegularBinEditor.unit.spec-AMGPMY7U.js +274 -0
- package/dist/NumSplineEditor-YDNJ2DW2.js +205 -0
- package/dist/NumSplineEditor.unit.spec-L4JZ3OND.js +220 -0
- package/dist/NumericDensity-SQW67WKL.js +29 -0
- package/dist/NumericDensity.unit.spec-KBK3JZZG.js +414 -0
- package/dist/NumericHandler-HG7FK4D4.js +30 -0
- package/dist/NumericHandler.unit.spec-N7PYAGGF.js +225 -0
- package/dist/ProteomeInput-6XGREJFP.js +610 -0
- package/dist/Regression-4DDXNQNO.js +1412 -0
- package/dist/RunChart2-ARCUC4Z3.js +744 -0
- package/dist/SC-AV6COOPI.js +1290 -0
- package/dist/Violin-2P5I6NL5.js +1105 -0
- package/dist/Volcano-TZQF3HY6.js +2745 -0
- package/dist/Volcano-TZQF3HY6.js.map +7 -0
- package/dist/Wsi-KN26SIP3.js +650 -0
- package/dist/Wsi-KN26SIP3.js.map +7 -0
- package/dist/aboutSunburst-V557OK5L.js +93 -0
- package/dist/adSandbox-76PMWKTX.js +29 -0
- package/dist/animatedBubbleChart-CFRJJDAC.js +542 -0
- package/dist/app-2SUVPURX.js +38 -0
- package/dist/app-PR42RXHC.js +28 -0
- package/dist/app.js +12 -12
- package/dist/bam-AYHWKHXL.js +872 -0
- package/dist/barchart-S4CLMJO7.js +38 -0
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- package/dist/block-QKO2PO4A.js +6208 -0
- package/dist/block-QKO2PO4A.js.map +7 -0
- package/dist/block.init-SSWOFFJR.js +29 -0
- package/dist/block.mds.expressionrank-GJBLSUUM.js +350 -0
- package/dist/block.mds.geneboxplot-SAAU4OH5.js +819 -0
- package/dist/block.mds.junction-IIZPRLPH.js +1534 -0
- package/dist/block.mds.svcnv-KOG7O25F.js +6325 -0
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- package/dist/block.tk.aicheck-CTIJCHIC.js +274 -0
- package/dist/block.tk.bam-RTB7C6CW.js +1906 -0
- package/dist/block.tk.bigwig.ui-OJVOCOWS.js +202 -0
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- package/dist/block.tk.junction.textmatrixui-OF6BW6OY.js +190 -0
- package/dist/block.tk.ld-QZVJUGZU.js +90 -0
- package/dist/block.tk.menu-B2NV6ZX3.js +1050 -0
- package/dist/block.tk.pgv-46OQHX7S.js +934 -0
- package/dist/brainImaging-TWTGRSHJ.js +550 -0
- package/dist/brainRegions-YTTLJMBU.js +213 -0
- package/dist/bubbleHeatmap-OZVG67KF.js +374 -0
- package/dist/bubbleHeatmap-OZVG67KF.js.map +7 -0
- package/dist/cellTypeBubbleHeatmap-4QFAAED5.js +274 -0
- package/dist/cellTypeBubbleHeatmap-4QFAAED5.js.map +7 -0
- package/dist/chunk-255OQYGC.js +267 -0
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- package/dist/cohort-TLSGXKV5.js +66 -0
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- package/dist/controls-472G34VU.js +30 -0
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- package/dist/customdata.inputui-EWYP4MRY.js +280 -0
- package/dist/dataDownload-X5UXBEK4.js +326 -0
- package/dist/databrowser.ui-PFHJKHIW.js +424 -0
- package/dist/dictionary-M2MCNRN2.js +109 -0
- package/dist/dnaMethylation-A7AWG2P5.js +29 -0
- package/dist/dnaMethylation.integration.spec-JWCMRFAM.js +194 -0
- package/dist/dnaMethylation.unit.spec-PIVJBW7Z.js +95 -0
- package/dist/dofetch-XID2XEJT.js +49 -0
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- package/dist/ep-BZE65IX2.js +1247 -0
- package/dist/expclust.gdc.spec-5BGBANUV.js +298 -0
- package/dist/facet-RXUO4LRY.js +556 -0
- package/dist/gb-NDRFDS5A.js +77 -0
- package/dist/geneExpClustering-ONJGTSGM.js +240 -0
- package/dist/geneExpression-NXDXXKEA.js +309 -0
- package/dist/geneExpression-PYI42HV6.js +29 -0
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- package/dist/geneORA-SDR43UOL.js +269 -0
- package/dist/geneRanking-QI43IRNV.js +544 -0
- package/dist/geneVariant-OT4V554H.js +32 -0
- package/dist/geneVariant-V7EKM7RW.js +289 -0
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- package/dist/genefusion.ui-IQDKCZPX.js +299 -0
- package/dist/geneset-TLZPZOQP.js +199 -0
- package/dist/genomeBrowser.spec-HIOTFKFK.js +272 -0
- package/dist/grin2-G2PVFRKR.js +945 -0
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- package/dist/hierCluster-C6ICZSOB.js +51 -0
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- package/dist/isoformExpression-TMLFOZVK.js +31 -0
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- /package/dist/{selectGenomeWithTklst-DPDBDYTR.js.map → selectGenomeWithTklst-XHWBEM2G.js.map} +0 -0
- /package/dist/{singleCellCellType-STVPYZD4.js.map → singleCellCellType-NP7Y4N6Z.js.map} +0 -0
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- /package/dist/{singleCellGeneExpression.unit.spec-PSLKK362.js.map → singleCellGeneExpression.unit.spec-2X2BDTNO.js.map} +0 -0
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- /package/dist/{studyCatalog-W5PATRNY.js.map → studyCatalog-UZ4BSYY6.js.map} +0 -0
- /package/dist/{summarizeCnvGeneexp-YGI23QH5.js.map → summarizeCnvGeneexp-Z43GYKZB.js.map} +0 -0
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- /package/dist/{summary-4WQOVIUF.js.map → summary-FZQVK5KR.js.map} +0 -0
- /package/dist/{summary.integration.spec-FRNWBU7F.js.map → summary.integration.spec-46T65LR5.js.map} +0 -0
- /package/dist/{summaryInput-X7DS2YA7.js.map → summaryInput-BHU7G5FC.js.map} +0 -0
- /package/dist/{sunburst-MSGTXYMM.js.map → sunburst-A5NS3KJQ.js.map} +0 -0
- /package/dist/{sunburst-3OEAQA3O.js.map → sunburst-R5X2C7FK.js.map} +0 -0
- /package/dist/{survival-5KC5CNZU.js.map → survival-MKW5J5ZH.js.map} +0 -0
- /package/dist/{survival-QXDS6N46.js.map → survival-N2NKMVOV.js.map} +0 -0
- /package/dist/{survival.integration.spec-PKENHLTZ.js.map → survival.integration.spec-K5FMOOTF.js.map} +0 -0
- /package/dist/{svgraph-VJLB7BBN.js.map → svgraph-3WRCJA5D.js.map} +0 -0
- /package/dist/{swimmer-R3DN7N36.js.map → swimmer-XV5KVWEM.js.map} +0 -0
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- /package/dist/{termCollection-3KGLZFDW.js.map → termCollection-NWTAUSSW.js.map} +0 -0
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- /package/dist/{termCollectionFractionSelection-MK4NKWUX.js.map → termCollectionFractionSelection-5FLFLMIY.js.map} +0 -0
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- /package/dist/{tvs.categorical-HY3BWCZR.js.map → tvs.categorical-24OT3XZI.js.map} +0 -0
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- /package/dist/{tvs.dtitd-SDSLBBWC.js.map → tvs.dtitd-MCJZCNV2.js.map} +0 -0
- /package/dist/{tvs.dtsnvindel-LI7K464K.js.map → tvs.dtsnvindel-K5YIIBQJ.js.map} +0 -0
- /package/dist/{tvs.dtsv-VRCLX7QY.js.map → tvs.dtsv-RP7FUB2N.js.map} +0 -0
- /package/dist/{tvs.multivalue-4OTY6J2S.js.map → tvs.multivalue-CROMWUCP.js.map} +0 -0
- /package/dist/{tvs.numeric-CDATYOR2.js.map → tvs.numeric-IYYYV6ZJ.js.map} +0 -0
- /package/dist/{tvs.samplelst-76JOJG2M.js.map → tvs.samplelst-5DXKRFYM.js.map} +0 -0
- /package/dist/{tvs.survival-WTFJOKIZ.js.map → tvs.survival-W5RXODBT.js.map} +0 -0
- /package/dist/{tvs.termCollection-QQXAS7PE.js.map → tvs.termCollection-OSJYIWDX.js.map} +0 -0
- /package/dist/{vocabulary-6ACAEFTL.js.map → vocabulary-HTRYJUD7.js.map} +0 -0
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@@ -0,0 +1,562 @@
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import {
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getSortSamplesByAncestry
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} from "./chunk-C2MCQZWH.js";
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import {
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isDictionaryType
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} from "./chunk-CFYWQJ7F.js";
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import {
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dtcnv,
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dtfusionrna,
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dtsnvindel,
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mclasscnvAmp,
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mclasscnvHomozygousDel,
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mclasscnvgain,
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mclasscnvloh,
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mclasscnvloss
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} from "./chunk-2N345NXD.js";
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// plots/matrix/matrix.sort.js
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function getSampleSorter(self, settings, rows, opts = {}) {
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const s = settings;
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validateSettings(s);
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if (self.config.chartType == "hierCluster" && self.config.settings.hierCluster.clusterSamples) {
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return self.hcSampleSorter;
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}
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if (s.sortSamplesBy == "asListed") {
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return (a, b) => {
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return self.asListedSampleOrder.indexOf(a.sample) - self.asListedSampleOrder.indexOf(b.sample);
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};
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}
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if (s.sortSamplesBy == "name") {
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return sortSamplesByName;
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}
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const activeOption = s.sortOptions[s.sortSamplesBy];
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if (!activeOption) throw `unsupported s.sortSamplesBy='${s.sortSamplesBy}'`;
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self.selectedTermsToSortAgainst = self.termOrder.filter((t) => t.tw.sortSamples);
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const selectedTerms = self.selectedTermsToSortAgainst.map((t) => t.tw).sort((a, b) => a.sortSamples.priority - b.sortSamples.priority);
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const sorterTerms = [];
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if (self.config.chartType == "matrix" && s.sortBySampleAncestry === "first")
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sorterTerms.push(getSortSamplesByAncestry(self));
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const sortPriority = activeOption.sortPriority;
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if (sortPriority) {
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for (const _tw of selectedTerms) {
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const tw = structuredClone(_tw);
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if (tw.sortSamples?.by) {
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sorterTerms.push(Object.assign({}, tw));
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continue;
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}
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for (const p of sortPriority) {
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if (opts.skipSorter?.(p, tw)) continue;
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const type = tw.term.type == "geneVariant" && tw.q.type != "values" ? "categorical" : tw.term.type;
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if (!p.types.includes(type)) continue;
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for (const tb of p.tiebreakers) {
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const sortSamples = Object.assign(structuredClone(tw.sortSamples || {}), tb);
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const sorter = Object.assign(structuredClone(tw), { sortSamples });
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sorterTerms.push(sorter);
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}
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}
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}
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}
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if (sortPriority) {
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for (const p of sortPriority) {
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for (const t of self.termOrder) {
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if (selectedTerms.find((tw) => tw.$id === t.tw.$id)) continue;
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if (opts.skipSorter?.(p, t.tw)) continue;
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if (!p.types.includes(t.tw.term.type)) continue;
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for (const tb of p.tiebreakers) {
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sorterTerms.push(Object.assign({}, t.tw, { sortSamples: tb }));
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}
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}
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}
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} else {
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const unSelectedDictTerms = self.app.vocabApi.vocab?.dslabel == "PNET" ? [] : self.termOrder.filter(
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(t) => !t.tw.sortSamples && isDictionaryType(t.tw.term.type) && !selectedTerms.find((tw) => tw.$id === t.tw.$id)
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).map((t) => Object.assign({ sortSamples: { by: "values" } }, t.tw));
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const unSelectedNonDictTerms = self.app.vocabApi.vocab?.dslabel == "PNET" ? [] : self.termOrder.filter(
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(t) => !t.tw.sortSamples && !isDictionaryType(t.tw.term.type) && !selectedTerms.find((tw) => tw.$id === t.tw.$id)
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).map((t) => Object.assign({ sortSamples: { by: "hits" } }, t.tw));
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sorterTerms.push(...unSelectedNonDictTerms, ...unSelectedDictTerms);
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}
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if (opts.tiebreaker) sorterTerms.push(opts.tiebreaker);
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sorterTerms.push(...s.sortSamplesTieBreakers.map((st) => st));
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const sampleSorters = [];
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self.maxSampleSet = /* @__PURE__ */ new Set();
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for (const st of sorterTerms) {
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if (typeof st === "function") sampleSorters.push(st);
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else if (st.$id == "sample") sampleSorters.push(sortSamplesByName);
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else if (st.sortSamples.by == "hits") sampleSorters.push(getSortSamplesByHits(st, self, rows, s));
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else if (st.term.type != "geneVariant") sampleSorters.push(getSortSamplesByValues(st, self, rows, s));
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else if (st.sortSamples.by == "values") sampleSorters.push(getSortSamplesByValues(st, self, rows, s));
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else if (st.sortSamples.by == "dt") sampleSorters.push(getSortSamplesByDt(st, self, rows, s));
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91
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else if (st.sortSamples.by == "class") sampleSorters.push(getSortSamplesByClass(st, self, rows, s));
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92
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else throw `unsupported sortSamplesBy entry by='${st.sortSamples.by}'`;
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}
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94
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if (!sampleSorters.find((f) => f.$id === "sample")) {
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sampleSorters.push(sortSamplesByName);
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}
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97
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return (a, b) => {
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98
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for (const sorter of sampleSorters) {
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const i = sorter(a, b);
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if (i !== 0) return i;
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}
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};
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103
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}
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104
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function validateSettings(s) {
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105
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if (!s.sortOptions) s.sortOptions = "custom";
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if (["selectedTerms", "class", "dt", "hits"].includes(s.sortSamplesBy)) s.sortSamplesBy = "custom";
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}
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108
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function sortSamplesByName(a, b) {
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109
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if (a._ref_.label && b._ref_.label) {
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return a._ref_.label < b._ref_.label ? -1 : a._ref_.label > b._ref_.label ? 1 : 0;
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111
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}
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112
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+
if (!a.sample && !b.sample && a.row.sample) {
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return a.row.sample < b.row.sample ? -1 : a.row.sample > b.row.sample ? 1 : 0;
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114
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}
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115
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return a.sample < b.sample ? -1 : a.sample > b.sample ? 1 : 0;
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}
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117
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function getSortSamplesByHits(st, self, rows, s) {
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118
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const { $id, sortSamples } = st;
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119
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const hits = {};
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120
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for (const row of rows) {
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121
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if (!hits[row.sample]) hits[row.sample] = 0;
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if ($id in row) {
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hits[row.sample] += row[$id].countedValues?.length || 0;
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}
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125
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}
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126
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return (a, b) => hits[a.sample] == hits[b.sample] ? 0 : hits[a.sample] > hits[b.sample] ? -1 : 1;
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}
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128
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function getSortSamplesByValues(st, self, rows, s) {
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129
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const { $id, sortSamples } = st;
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const t = self.termOrder.find((t2) => t2.tw.$id === $id);
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131
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if (t.grp.type == "hierCluster") {
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return (a, b) => {
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if ($id in a && $id in b) {
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return a[$id]?.values[0].value - b[$id]?.values[0].value;
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}
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136
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if ($id in a) return -1;
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137
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if ($id in b) return 1;
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return 0;
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139
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};
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140
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}
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141
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if (t.tw.term.type == "termCollection") {
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142
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return (a, b) => {
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143
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if ($id in a && $id in b) {
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144
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return a[$id]?.numerators_sum - b[$id]?.numerators_sum;
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145
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}
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146
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+
if ($id in a) return -1;
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147
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+
if ($id in b) return 1;
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148
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return 0;
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149
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};
|
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150
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+
}
|
|
151
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+
if (t.tw.q?.mode == "continuous") {
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152
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return (a, b) => {
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153
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if ($id in a && $id in b) {
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154
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return a[$id]?.value - b[$id]?.value;
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155
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}
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156
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+
if ($id in a) return -1;
|
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157
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+
if ($id in b) return 1;
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158
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+
return 0;
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159
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+
};
|
|
160
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+
}
|
|
161
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+
const values = [];
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|
162
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+
if (t?.term?.values) {
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163
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+
for (const v of term.values) {
|
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164
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values.push(v.key);
|
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165
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+
}
|
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166
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+
values.sort((a, b) => term.values[a].order < term.values[a].order ? -1 : 1);
|
|
167
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+
} else if (t?.ref?.bins) {
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168
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values.push(...t.ref.bins.map((b) => b.name));
|
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169
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+
} else if (t.tw.q?.type == "predefined-groupset" || t.tw.q?.type == "custom-groupset") {
|
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170
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+
const groupset = t.tw.q.type == "predefined-groupset" ? t.tw.term.groupsetting.lst[t.tw.q.predefined_groupset_idx] : t.tw.q.customset;
|
|
171
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+
if (!groupset) throw "groupset missing";
|
|
172
|
+
const grpNames = groupset.groups.filter((group) => !group.uncomputable).map((group) => group.name);
|
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173
|
+
values.push(...grpNames);
|
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174
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+
} else {
|
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175
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+
for (const row of rows) {
|
|
176
|
+
if (!($id in row)) continue;
|
|
177
|
+
const v = row[$id].override?.key || row[$id].key;
|
|
178
|
+
if (values.indexOf(v) == -1) values.push(v);
|
|
179
|
+
}
|
|
180
|
+
}
|
|
181
|
+
return (a, b) => {
|
|
182
|
+
if (!a[$id] && !b[$id]) return 0;
|
|
183
|
+
if (!a[$id]) return b[$id].override ? -1 : 1;
|
|
184
|
+
if (!b[$id]) return a[$id].override ? 1 : -1;
|
|
185
|
+
if (a[$id].override && b[$id].override) {
|
|
186
|
+
const ak = "order" in a[$id].override ? a[$id].override.order : values.indexOf(a[$id].override.key);
|
|
187
|
+
const bk = "order" in b[$id].override ? b[$id].override.order : values.indexOf(b[$id].override.key);
|
|
188
|
+
return ak - bk;
|
|
189
|
+
}
|
|
190
|
+
if (!a[$id].override && !b[$id].override) {
|
|
191
|
+
return values.indexOf(a[$id].key) - values.indexOf(b[$id].key);
|
|
192
|
+
}
|
|
193
|
+
if (!a[$id].override) return -1;
|
|
194
|
+
if (!b[$id].override) return 1;
|
|
195
|
+
return 0;
|
|
196
|
+
};
|
|
197
|
+
}
|
|
198
|
+
function getSortSamplesByDt(st, self, rows, s) {
|
|
199
|
+
const { $id, sortSamples, term: term2 } = st;
|
|
200
|
+
const order = sortSamples.order;
|
|
201
|
+
const nextRound = order.length + 1;
|
|
202
|
+
const dt = /* @__PURE__ */ new Map();
|
|
203
|
+
function setSortIndex(row) {
|
|
204
|
+
if (!($id in row)) {
|
|
205
|
+
dt.set(row.sample, nextRound);
|
|
206
|
+
return;
|
|
207
|
+
}
|
|
208
|
+
const values = row[$id].filteredValues || row[$id].values;
|
|
209
|
+
if (sortSamples.filter && !findMatchingValue(values, sortSamples.filter.values)) {
|
|
210
|
+
dt.set(row.sample, nextRound);
|
|
211
|
+
return;
|
|
212
|
+
}
|
|
213
|
+
const indices = values.map((v) => order.indexOf(v.dt)).filter((i) => i !== -1);
|
|
214
|
+
dt.set(row.sample, indices.length ? Math.min(...indices) : nextRound);
|
|
215
|
+
}
|
|
216
|
+
return (a, b) => {
|
|
217
|
+
if (!dt.has(a.sample)) setSortIndex(a);
|
|
218
|
+
if (!dt.has(b.sample)) setSortIndex(b);
|
|
219
|
+
return dt.get(a.sample) - dt.get(b.sample);
|
|
220
|
+
};
|
|
221
|
+
}
|
|
222
|
+
function getSortSamplesByClass(st, self, rows, s) {
|
|
223
|
+
const { $id, sortSamples } = st;
|
|
224
|
+
if (sortSamples.disabled) return () => 0;
|
|
225
|
+
const m = self.config.settings.matrix;
|
|
226
|
+
const includeSSM = m.showMatrixMutation != "none" && !m.allMatrixMutationHidden;
|
|
227
|
+
const includeCNV = m.showMatrixCNV != "none" && !m.allMatrixCNVHidden;
|
|
228
|
+
const order = sortSamples.order.filter(
|
|
229
|
+
includeSSM && includeCNV ? (v) => !m.hiddenVariants.includes(v) : !includeSSM && !includeCNV ? () => false : includeSSM ? (v) => m.mutationClasses.includes(v) && !m.hiddenVariants.includes(v) : includeCNV ? (v) => v.startsWith("CNV_") && !m.hiddenVariants.includes(v) : (v) => !v.startsWith("CNV_")
|
|
230
|
+
);
|
|
231
|
+
if (!order.length && sortSamples.ignoreEmptyFilteredOrder) return () => 0;
|
|
232
|
+
const nextRound = "z";
|
|
233
|
+
const cls = /* @__PURE__ */ new Map();
|
|
234
|
+
function setSortIndex(row) {
|
|
235
|
+
if (!($id in row)) {
|
|
236
|
+
cls.set(row.sample, nextRound);
|
|
237
|
+
return;
|
|
238
|
+
}
|
|
239
|
+
const values = row[$id].renderedValues || row[$id].filteredValues || row[$id].values;
|
|
240
|
+
if (sortSamples.filter && !findMatchingValue(values, sortSamples.filter.values)) {
|
|
241
|
+
cls.set(row.sample, nextRound);
|
|
242
|
+
return;
|
|
243
|
+
}
|
|
244
|
+
const vals = values.map((v) => v.class);
|
|
245
|
+
if (!order.find((mcls) => vals.includes(mcls))) {
|
|
246
|
+
cls.set(row.sample, nextRound);
|
|
247
|
+
return;
|
|
248
|
+
} else if (!sortSamples.isOrdered) {
|
|
249
|
+
cls.set(row.sample, "1");
|
|
250
|
+
} else {
|
|
251
|
+
const str = order.map((mcls) => vals.includes(mcls) ? "1" : "x");
|
|
252
|
+
cls.set(row.sample, str);
|
|
253
|
+
}
|
|
254
|
+
}
|
|
255
|
+
return (a, b) => {
|
|
256
|
+
if (!cls.has(a.sample)) setSortIndex(a);
|
|
257
|
+
if (!cls.has(b.sample)) setSortIndex(b);
|
|
258
|
+
const ca = cls.get(a.sample);
|
|
259
|
+
const cb = cls.get(b.sample);
|
|
260
|
+
return ca < cb ? -1 : ca > cb ? 1 : 0;
|
|
261
|
+
};
|
|
262
|
+
}
|
|
263
|
+
function findMatchingValue(annoValues, filterValues) {
|
|
264
|
+
for (const v of annoValues) {
|
|
265
|
+
for (const f of filterValues) {
|
|
266
|
+
if ((!f.dt || v.dt === f.dt) && (!f.mclassLst || f.mclassLst.includes(v.class)) && (!f.class || f.class === v.class) && (!f.origin || v.origin === f.origin)) {
|
|
267
|
+
return true;
|
|
268
|
+
}
|
|
269
|
+
}
|
|
270
|
+
}
|
|
271
|
+
}
|
|
272
|
+
function getTermSorter(self, s, grp) {
|
|
273
|
+
if (grp?.type == "hierCluster") return self.hcTermSorter;
|
|
274
|
+
if (s.sortTermsBy == "asListed") {
|
|
275
|
+
return (a, b) => a.index - b.index;
|
|
276
|
+
}
|
|
277
|
+
if (s.sortTermsBy != "sampleCount") {
|
|
278
|
+
throw `unsupported s.sortTermsBy='${s.sortTermsBy}'`;
|
|
279
|
+
}
|
|
280
|
+
return (a, b) => {
|
|
281
|
+
if (self.app.vocabApi.termdbConfig?.matrix?.sortDictTermsFirst) {
|
|
282
|
+
if (a.tw?.term?.id && !b.tw?.term?.id) return -1;
|
|
283
|
+
if (!a.tw?.term?.id && b.tw?.term?.id) return 1;
|
|
284
|
+
}
|
|
285
|
+
if (b.counts.samples !== a.counts.samples) return b.counts.samples - a.counts.samples;
|
|
286
|
+
if (b.counts.hits !== a.counts.hits) return b.counts.hits - a.counts.hits;
|
|
287
|
+
return a.index - b.index;
|
|
288
|
+
};
|
|
289
|
+
}
|
|
290
|
+
function getSortOptions(termdbConfig, controlLabels = {}, matrixSettings) {
|
|
291
|
+
const s = matrixSettings || termdbConfig?.matrix?.settings || {};
|
|
292
|
+
const l = Object.assign({ sample: "sample" }, controlLabels, s.controlLabels || {});
|
|
293
|
+
const sortOptions = {};
|
|
294
|
+
if (s.sortPriority) {
|
|
295
|
+
const order = 1;
|
|
296
|
+
Object.values(sortOptions).forEach((d) => {
|
|
297
|
+
if (d.order >= order) d.order += 1;
|
|
298
|
+
});
|
|
299
|
+
sortOptions.custom = {
|
|
300
|
+
label: s.sortPriority.label || "Custom sort",
|
|
301
|
+
value: "custom",
|
|
302
|
+
order,
|
|
303
|
+
sortPriority: s.sortPriority
|
|
304
|
+
};
|
|
305
|
+
}
|
|
306
|
+
const cnvClasses = [mclasscnvAmp, mclasscnvHomozygousDel, mclasscnvgain, mclasscnvloss, mclasscnvloh];
|
|
307
|
+
const proteinChangingClasses = (s.proteinChangingMutations || []).filter(
|
|
308
|
+
(mcls) => !s.truncatingMutations.includes(mcls)
|
|
309
|
+
);
|
|
310
|
+
const sortedClasses = ["Fuserna", ...s.truncatingMutations || [], ...cnvClasses, ...proteinChangingClasses];
|
|
311
|
+
sortOptions.a = s.sortOptions?.a ? reshapeSortPriority(s.sortOptions.a, l) : {
|
|
312
|
+
//label: l.Mutation + ' categories', //'CNV+SSM > SSM-only > CNV-only',
|
|
313
|
+
// altLabels: {
|
|
314
|
+
// mutationOnly: 'SSM',
|
|
315
|
+
// cnvOnly: 'CNV',
|
|
316
|
+
// },
|
|
317
|
+
value: "a",
|
|
318
|
+
order: 1,
|
|
319
|
+
// this is used for list order as a sorter option in a dropdown
|
|
320
|
+
sortPriority: [
|
|
321
|
+
{
|
|
322
|
+
label: `For each gene mutation, sort ${l.samples} by matching data`,
|
|
323
|
+
types: ["geneVariant"],
|
|
324
|
+
tiebreakers: [
|
|
325
|
+
{
|
|
326
|
+
skip: !s.mutationClasses.includes("Fuserna"),
|
|
327
|
+
// not visible, cannot be enabled
|
|
328
|
+
label: `${l.Samples} with Fusion RNASeq > without`,
|
|
329
|
+
filter: {
|
|
330
|
+
values: [
|
|
331
|
+
{
|
|
332
|
+
dt: dtfusionrna
|
|
333
|
+
}
|
|
334
|
+
]
|
|
335
|
+
},
|
|
336
|
+
by: "class",
|
|
337
|
+
isOrdered: false,
|
|
338
|
+
order: [
|
|
339
|
+
"Fuserna"
|
|
340
|
+
/*'WT', 'Blank'*/
|
|
341
|
+
]
|
|
342
|
+
},
|
|
343
|
+
{
|
|
344
|
+
label: `${l.Samples} with truncating mutations > without`,
|
|
345
|
+
filter: {
|
|
346
|
+
values: [
|
|
347
|
+
{
|
|
348
|
+
dt: dtsnvindel
|
|
349
|
+
}
|
|
350
|
+
]
|
|
351
|
+
},
|
|
352
|
+
by: "class",
|
|
353
|
+
isOrdered: false,
|
|
354
|
+
order: [
|
|
355
|
+
...s.truncatingMutations
|
|
356
|
+
// // truncating
|
|
357
|
+
// 'F', // FRAMESHIFT
|
|
358
|
+
// 'N', // NONSENSE
|
|
359
|
+
// 'L', // SPLICE
|
|
360
|
+
// 'P', // SPLICE_REGION
|
|
361
|
+
// // indel
|
|
362
|
+
// 'D', // PROTEINDEL
|
|
363
|
+
// 'I', // PROTEININS
|
|
364
|
+
// 'ProteinAltering',
|
|
365
|
+
// // point
|
|
366
|
+
// 'M' // MISSENSE
|
|
367
|
+
],
|
|
368
|
+
// do not have the option to add unused protein-changing mutations,
|
|
369
|
+
// because the "truncating" label for this tiebreaker will not make sense
|
|
370
|
+
notUsed: []
|
|
371
|
+
},
|
|
372
|
+
{
|
|
373
|
+
label: `${l.Samples} with CNV data > without`,
|
|
374
|
+
mayToggle: true,
|
|
375
|
+
filter: {
|
|
376
|
+
values: [
|
|
377
|
+
{
|
|
378
|
+
dt: dtcnv
|
|
379
|
+
}
|
|
380
|
+
]
|
|
381
|
+
},
|
|
382
|
+
by: "class",
|
|
383
|
+
isOrdered: true,
|
|
384
|
+
disabled: true,
|
|
385
|
+
// visible, can be enabled
|
|
386
|
+
order: cnvClasses
|
|
387
|
+
},
|
|
388
|
+
{
|
|
389
|
+
disabled: false,
|
|
390
|
+
mayToggle: true,
|
|
391
|
+
label: `${l.Samples} with protein-changing mutations > without`,
|
|
392
|
+
filter: {
|
|
393
|
+
values: [
|
|
394
|
+
{
|
|
395
|
+
dt: dtsnvindel
|
|
396
|
+
}
|
|
397
|
+
]
|
|
398
|
+
},
|
|
399
|
+
by: "class",
|
|
400
|
+
isOrdered: false,
|
|
401
|
+
// by default, do not include truncating mutations here since they may
|
|
402
|
+
// already be used in the tiebreaker with truncating mutations
|
|
403
|
+
order: proteinChangingClasses,
|
|
404
|
+
notUsed: s.truncatingMutations
|
|
405
|
+
},
|
|
406
|
+
{
|
|
407
|
+
disabled: false,
|
|
408
|
+
mayToggle: true,
|
|
409
|
+
label: `${l.Samples} with other classification > without`,
|
|
410
|
+
filter: {
|
|
411
|
+
values: [
|
|
412
|
+
{
|
|
413
|
+
dt: dtsnvindel
|
|
414
|
+
}
|
|
415
|
+
]
|
|
416
|
+
},
|
|
417
|
+
by: "class",
|
|
418
|
+
isOrdered: false,
|
|
419
|
+
order: s.mutationClasses.filter((cls) => !sortedClasses.includes(cls) && cls != "Blank"),
|
|
420
|
+
notUsed: []
|
|
421
|
+
}
|
|
422
|
+
]
|
|
423
|
+
},
|
|
424
|
+
{
|
|
425
|
+
label: `For each dictionary variable, sort ${l.samples} by matching data`,
|
|
426
|
+
types: ["categorical", "integer", "float", "survival"],
|
|
427
|
+
tiebreakers: [
|
|
428
|
+
{
|
|
429
|
+
label: "Values",
|
|
430
|
+
by: "values"
|
|
431
|
+
}
|
|
432
|
+
]
|
|
433
|
+
}
|
|
434
|
+
]
|
|
435
|
+
};
|
|
436
|
+
sortOptions.name = {
|
|
437
|
+
label: `By ${l.sample} name, ID, or label`,
|
|
438
|
+
value: "name",
|
|
439
|
+
order: Object.values(sortOptions).length
|
|
440
|
+
};
|
|
441
|
+
return sortOptions;
|
|
442
|
+
}
|
|
443
|
+
function getSampleGroupSorter(self) {
|
|
444
|
+
const s = self.settings.matrix;
|
|
445
|
+
if (s.sortSampleGrpsBy == "hits")
|
|
446
|
+
return (a, b) => {
|
|
447
|
+
if (a.lst.length && !b.lst.length) return -1;
|
|
448
|
+
if (!a.lst.length && b.lst.length) return 1;
|
|
449
|
+
return b.totalCountedValues - a.totalCountedValues;
|
|
450
|
+
};
|
|
451
|
+
if (s.sortSampleGrpsBy == "sampleCount")
|
|
452
|
+
return (a, b) => {
|
|
453
|
+
if (a.lst.length && !b.lst.length) return -1;
|
|
454
|
+
if (!a.lst.length && b.lst.length) return 1;
|
|
455
|
+
if (a.lst.length == b.lst.length) {
|
|
456
|
+
return defaultSorter(a, b);
|
|
457
|
+
}
|
|
458
|
+
return b.lst.length - a.lst.length;
|
|
459
|
+
};
|
|
460
|
+
if (!self.config.divideBy?.$id) return defaultSorter;
|
|
461
|
+
const ref = self.data.refs.byTermId[self.config.divideBy.$id];
|
|
462
|
+
if (ref && !ref.keyOrder) ref.keyOrder = ref.bins ? ref.bins.map((b) => b.name) : [];
|
|
463
|
+
const predefinedKeyOrder = self.data.refs.byTermId[self.config.divideBy.$id]?.keyOrder;
|
|
464
|
+
if (!predefinedKeyOrder) return defaultSorter;
|
|
465
|
+
return (a, b) => {
|
|
466
|
+
a.order = predefinedKeyOrder.indexOf(a.id);
|
|
467
|
+
if (a.order == -1) delete a.order;
|
|
468
|
+
b.order = predefinedKeyOrder.indexOf(b.id);
|
|
469
|
+
if (b.order == -1) delete b.order;
|
|
470
|
+
if ("order" in a && "order" in b) return a.order - b.order;
|
|
471
|
+
if ("order" in a) return -1;
|
|
472
|
+
if ("order" in b) return 1;
|
|
473
|
+
if (a.tw?.term?.values?.[a.id]?.order && b.tw?.term?.values?.[b.id]?.order) {
|
|
474
|
+
return a.tw.term.values[a.id].order - b.tw.term.values[b.id].order;
|
|
475
|
+
}
|
|
476
|
+
return defaultSorter(a, b);
|
|
477
|
+
};
|
|
478
|
+
}
|
|
479
|
+
function defaultSorter(a, b) {
|
|
480
|
+
return a.name < b.name ? -1 : 1;
|
|
481
|
+
}
|
|
482
|
+
function getMclassSorter(self) {
|
|
483
|
+
const s = self.settings.matrix;
|
|
484
|
+
const activeOption = s.sortOptions[s.sortSamplesBy].sortPriority ? s.sortOptions[s.sortSamplesBy] : s.sortOptions.a;
|
|
485
|
+
const mclassPriority = [];
|
|
486
|
+
activeOption.sortPriority.forEach((obj) => {
|
|
487
|
+
if (obj.types.includes("geneVariant")) {
|
|
488
|
+
obj.tiebreakers.forEach((tiebreaker) => {
|
|
489
|
+
if (tiebreaker.by == "class" && tiebreaker.order) {
|
|
490
|
+
mclassPriority.push(...tiebreaker.order.filter((t) => t !== "WT" && t !== "Blank"));
|
|
491
|
+
}
|
|
492
|
+
});
|
|
493
|
+
}
|
|
494
|
+
});
|
|
495
|
+
const sorter = (a, b) => {
|
|
496
|
+
const ai = mclassPriority.indexOf(a.class);
|
|
497
|
+
const bi = mclassPriority.indexOf(b.class);
|
|
498
|
+
return ai == -1 && bi == -1 ? 0 : mclassPriority.indexOf(a.class) == -1 ? 1 : mclassPriority.indexOf(b.class) == -1 ? -1 : mclassPriority.indexOf(a.class) - mclassPriority.indexOf(b.class);
|
|
499
|
+
};
|
|
500
|
+
return sorter;
|
|
501
|
+
}
|
|
502
|
+
function reshapeSortPriority(sortOption, labels) {
|
|
503
|
+
const l = labels;
|
|
504
|
+
let geneVariantsEntry;
|
|
505
|
+
for (const sp of sortOption.sortPriority) {
|
|
506
|
+
if (sp.types.includes("categorical")) {
|
|
507
|
+
if (!sp.label) sp.label = `For each dictionary variable, sort ${l.samples} by matching data`;
|
|
508
|
+
continue;
|
|
509
|
+
}
|
|
510
|
+
if (!sp.types?.includes("geneVariant")) continue;
|
|
511
|
+
if (!geneVariantsEntry) {
|
|
512
|
+
geneVariantsEntry = sp;
|
|
513
|
+
if (!sp.label) sp.label = `For each gene mutation, sort ${l.samples} by matching data`;
|
|
514
|
+
} else {
|
|
515
|
+
geneVariantsEntry.tiebreakers.push(...sp.tiebreakers);
|
|
516
|
+
sp.toBeDeleted = true;
|
|
517
|
+
}
|
|
518
|
+
}
|
|
519
|
+
for (const tb of geneVariantsEntry.tiebreakers) {
|
|
520
|
+
const origClone = structuredClone(tb);
|
|
521
|
+
if (tb.filter?.values?.find((v) => v.dt == dtfusionrna)) {
|
|
522
|
+
const defaults = {
|
|
523
|
+
label: `${l.Samples} with Fusion RNASeq > without`,
|
|
524
|
+
isOrdered: true,
|
|
525
|
+
disabled: false,
|
|
526
|
+
mayToggle: true
|
|
527
|
+
};
|
|
528
|
+
Object.assign(tb, defaults, origClone);
|
|
529
|
+
} else if (tb.filter?.values?.find((v) => v.dt == dtsnvindel)) {
|
|
530
|
+
const label = tb.order.includes(mclasscnvgain) || tb.order.includes(mclasscnvloss) ? `${l.Samples} with SSM + CNV > SSM only` : `${l.Samples} with mutations`;
|
|
531
|
+
const defaults = {
|
|
532
|
+
label,
|
|
533
|
+
isOrdered: true,
|
|
534
|
+
disabled: false,
|
|
535
|
+
mayToggle: true
|
|
536
|
+
};
|
|
537
|
+
Object.assign(tb, defaults, origClone);
|
|
538
|
+
} else if (tb.order.length == 2 && tb.order.includes(mclasscnvgain) && tb.order.includes(mclasscnvloss)) {
|
|
539
|
+
const defaults = {
|
|
540
|
+
label: `${l.Samples} with CNV only > without`,
|
|
541
|
+
filter: { values: [{ dt: dtcnv }] },
|
|
542
|
+
by: "class",
|
|
543
|
+
isOrdered: true,
|
|
544
|
+
disabled: false,
|
|
545
|
+
mayToggle: true
|
|
546
|
+
};
|
|
547
|
+
Object.assign(tb, defaults, origClone);
|
|
548
|
+
}
|
|
549
|
+
}
|
|
550
|
+
sortOption.sortPriority = sortOption.sortPriority.filter((sp) => !sp.toBeDeleted);
|
|
551
|
+
return sortOption;
|
|
552
|
+
}
|
|
553
|
+
|
|
554
|
+
export {
|
|
555
|
+
getSampleSorter,
|
|
556
|
+
getTermSorter,
|
|
557
|
+
getSortOptions,
|
|
558
|
+
getSampleGroupSorter,
|
|
559
|
+
getMclassSorter,
|
|
560
|
+
reshapeSortPriority
|
|
561
|
+
};
|
|
562
|
+
//# sourceMappingURL=chunk-SB5DR4NL.js.map
|
|
@@ -0,0 +1,100 @@
|
|
|
1
|
+
import {
|
|
2
|
+
junctionCustomTermSource
|
|
3
|
+
} from "./chunk-FIWVGOSE.js";
|
|
4
|
+
import {
|
|
5
|
+
getTermSampleTypes,
|
|
6
|
+
mayRenderFractionSelection,
|
|
7
|
+
mayRenderSampleTypeRow
|
|
8
|
+
} from "./chunk-CXCAQOFB.js";
|
|
9
|
+
import {
|
|
10
|
+
getTermLabelSuffix
|
|
11
|
+
} from "./chunk-CFYWQJ7F.js";
|
|
12
|
+
|
|
13
|
+
// termdb/handlers/junction.ts
|
|
14
|
+
var SearchHandler = class {
|
|
15
|
+
async init(opts) {
|
|
16
|
+
if (!opts?.holder) throw new Error("opts.holder is required");
|
|
17
|
+
if (typeof opts.callback != "function") throw new Error("opts.callback is required");
|
|
18
|
+
const entries = getJunctionCustomTerms(opts.app.vocabApi.state?.customTerms);
|
|
19
|
+
render(opts, entries);
|
|
20
|
+
}
|
|
21
|
+
};
|
|
22
|
+
function getJunctionCustomTerms(customTerms) {
|
|
23
|
+
if (!Array.isArray(customTerms)) return [];
|
|
24
|
+
return customTerms.filter((term) => term?.source === junctionCustomTermSource && term.tw?.term);
|
|
25
|
+
}
|
|
26
|
+
function render(opts, entries) {
|
|
27
|
+
const holder = opts.holder;
|
|
28
|
+
holder.selectAll("*").remove();
|
|
29
|
+
const div = holder.append("div").style("padding", "10px 0px");
|
|
30
|
+
if (!entries.length) {
|
|
31
|
+
div.append("div").text("Junctions selected from genome browser will be shown here.");
|
|
32
|
+
return;
|
|
33
|
+
}
|
|
34
|
+
const termdbConfig = opts.app.vocabApi.termdbConfig;
|
|
35
|
+
const query = termdbConfig?.queries?.junction;
|
|
36
|
+
const sampleTypeSelect = mayRenderSampleTypeRow(div.append("div"), query, termdbConfig);
|
|
37
|
+
const pick = (termOrTw) => {
|
|
38
|
+
const termSampleTypes = getTermSampleTypes(sampleTypeSelect, query, termdbConfig);
|
|
39
|
+
if (!termSampleTypes) return;
|
|
40
|
+
const all = !termSampleTypes.sampleTypes?.length || query.sampleTypes.every((t) => termSampleTypes.sampleTypes.includes(t));
|
|
41
|
+
const apply = (term) => all ? term : withSampleTypes(term, termSampleTypes);
|
|
42
|
+
return opts.callback(termOrTw.term ? { ...termOrTw, term: apply(termOrTw.term) } : apply(termOrTw));
|
|
43
|
+
};
|
|
44
|
+
const listHolder = div.append("div");
|
|
45
|
+
const renderList = () => {
|
|
46
|
+
const entries2 = getJunctionCustomTerms(opts.app.vocabApi.state?.customTerms);
|
|
47
|
+
if (!entries2.length) return render(opts, entries2);
|
|
48
|
+
listHolder.selectAll("*").remove();
|
|
49
|
+
const itemOpts = { ...opts, callback: pick, renderList };
|
|
50
|
+
const listDiv = listHolder.append("div");
|
|
51
|
+
const fractionDiv = listHolder.append("div");
|
|
52
|
+
for (const entry of entries2) {
|
|
53
|
+
if (entry.eventlabel) renderJunctionEvent(listDiv, fractionDiv, entry, itemOpts);
|
|
54
|
+
else renderJunction(listDiv, entry, itemOpts);
|
|
55
|
+
}
|
|
56
|
+
listDiv.append("div").style("font-size", ".7em").style("margin-top", "10px").style("opacity", 0.7).text("Select additional junctions from genome browser.");
|
|
57
|
+
};
|
|
58
|
+
renderList();
|
|
59
|
+
}
|
|
60
|
+
function renderJunction(holder, entry, opts) {
|
|
61
|
+
const choice = holder.append("div");
|
|
62
|
+
choice.append("div").attr("class", "ts_pill sja_filter_tag_btn sja_tree_click_term").style("display", "inline-block").style("border-radius", "6px").style("margin", "1px 0").text(entry.tw.term.name).on("click", () => opts.callback(entry.tw.term));
|
|
63
|
+
addDeleteButton(choice, entry, opts);
|
|
64
|
+
}
|
|
65
|
+
function renderJunctionEvent(holder, fractionDiv, entry, opts) {
|
|
66
|
+
const eventHolder = holder.append("div");
|
|
67
|
+
const pillRow = eventHolder.append("div");
|
|
68
|
+
pillRow.append("div").attr("class", "ts_pill sja_filter_tag_btn sja_tree_click_term").style("display", "inline-block").style("border-radius", "6px").style("margin", "1px 0").text(entry.eventlabel).on("click", () => selectJunctionEvent(holder, fractionDiv, entry, opts));
|
|
69
|
+
addDeleteButton(pillRow, entry, opts);
|
|
70
|
+
eventHolder.append("div").style("margin-left", "10px").style("font-size", ".7em").selectAll("div").data(entry.tw.term.termlst, (term) => term.id).enter().append("div").text((term) => term.name);
|
|
71
|
+
}
|
|
72
|
+
function selectJunctionEvent(listDiv, fractionDiv, entry, opts) {
|
|
73
|
+
const isStaged = mayRenderFractionSelection({
|
|
74
|
+
term: entry.tw.term,
|
|
75
|
+
selectionMode: opts.termCollectionSelectionMode,
|
|
76
|
+
listDiv,
|
|
77
|
+
fractionDiv,
|
|
78
|
+
callback: (tw) => opts.callback(tw)
|
|
79
|
+
});
|
|
80
|
+
if (!isStaged) opts.callback(entry.tw.term);
|
|
81
|
+
}
|
|
82
|
+
function addDeleteButton(holder, entry, opts) {
|
|
83
|
+
holder.append("button").attr("data-testid", "sjpp-junction-delete").style("margin-left", "4px").attr("aria-label", `Delete ${entry.name}`).text("\xD7").on("click", async () => {
|
|
84
|
+
await opts.app.vocabApi.deleteCustomTermById(entry.id);
|
|
85
|
+
opts.renderList();
|
|
86
|
+
});
|
|
87
|
+
}
|
|
88
|
+
function withSampleTypes(term, termSampleTypes) {
|
|
89
|
+
const { sampleTypes, sampleTypeLabel } = termSampleTypes;
|
|
90
|
+
const t = { ...term, sampleTypes, sampleTypeLabel };
|
|
91
|
+
t.name = term.name + getTermLabelSuffix(t);
|
|
92
|
+
if (Array.isArray(term.termlst)) t.termlst = term.termlst.map((m) => ({ ...m, sampleTypes }));
|
|
93
|
+
return t;
|
|
94
|
+
}
|
|
95
|
+
|
|
96
|
+
export {
|
|
97
|
+
SearchHandler,
|
|
98
|
+
getJunctionCustomTerms
|
|
99
|
+
};
|
|
100
|
+
//# sourceMappingURL=chunk-SCATA75L.js.map
|
|
@@ -0,0 +1,7 @@
|
|
|
1
|
+
{
|
|
2
|
+
"version": 3,
|
|
3
|
+
"sources": ["../termdb/handlers/junction.ts"],
|
|
4
|
+
"sourcesContent": ["import { junctionCustomTermSource, type JunctionCustomTerm } from './junction.customTerm.ts'\nimport { mayRenderFractionSelection } from './termCollectionFractionSelection.ts'\nimport { mayRenderSampleTypeRow, getTermSampleTypes } from '#dom'\nimport { getTermLabelSuffix } from '#shared/terms.js'\n\nexport class SearchHandler {\n\tasync init(opts) {\n\t\tif (!opts?.holder) throw new Error('opts.holder is required')\n\t\tif (typeof opts.callback != 'function') throw new Error('opts.callback is required')\n\n\t\tconst entries = getJunctionCustomTerms(opts.app.vocabApi.state?.customTerms)\n\t\trender(opts, entries)\n\t}\n}\n\nexport function getJunctionCustomTerms(customTerms: any): JunctionCustomTerm[] {\n\tif (!Array.isArray(customTerms)) return []\n\treturn customTerms.filter(term => term?.source === junctionCustomTermSource && term.tw?.term)\n}\n\nfunction render(opts, entries: JunctionCustomTerm[]) {\n\tconst holder = opts.holder\n\tholder.selectAll('*').remove()\n\tconst div = holder.append('div').style('padding', '10px 0px')\n\n\tif (!entries.length) {\n\t\tdiv.append('div').text('Junctions selected from genome browser will be shown here.')\n\t\treturn\n\t}\n\n\t/* the sample types to read the picked junction for, as for gene expression and methylation terms.\n\tDrawn once: a delete redraws only the list below, so the choice stays */\n\tconst termdbConfig = opts.app.vocabApi.termdbConfig\n\tconst query = termdbConfig?.queries?.junction\n\tconst sampleTypeSelect = mayRenderSampleTypeRow(div.append('div'), query, termdbConfig)\n\t/* a junction or event term, or the term wrapper of an event's fraction from the fraction chooser, with\n\tthe chosen sample types, see withSampleTypes() */\n\tconst pick = (termOrTw: any) => {\n\t\tconst termSampleTypes = getTermSampleTypes(sampleTypeSelect, query, termdbConfig)\n\t\t// nothing selectable, which getTermSampleTypes() has alerted\n\t\tif (!termSampleTypes) return\n\t\t/* every sample type of the junction file, or its only one, is the same as no choice: the term then\n\t\treads every sample, as before there was a selector, including any sample without a sample type */\n\t\tconst all =\n\t\t\t!termSampleTypes.sampleTypes?.length || query.sampleTypes.every(t => termSampleTypes.sampleTypes!.includes(t))\n\t\tconst apply = (term: any) => (all ? term : withSampleTypes(term, termSampleTypes))\n\t\treturn opts.callback(termOrTw.term ? { ...termOrTw, term: apply(termOrTw.term) } : apply(termOrTw))\n\t}\n\n\tconst listHolder = div.append('div')\n\tconst renderList = () => {\n\t\tconst entries = getJunctionCustomTerms(opts.app.vocabApi.state?.customTerms)\n\t\t// the last one is deleted\n\t\tif (!entries.length) return render(opts, entries)\n\t\tlistHolder.selectAll('*').remove()\n\t\tconst itemOpts = { ...opts, callback: pick, renderList }\n\n\t\t// the fraction chooser is rendered in a sibling div, so that the list may be\n\t\t// restored without reloading, when the user backs out of the chooser\n\t\tconst listDiv = listHolder.append('div')\n\t\tconst fractionDiv = listHolder.append('div')\n\n\t\tfor (const entry of entries) {\n\t\t\tif (entry.eventlabel) renderJunctionEvent(listDiv, fractionDiv, entry, itemOpts)\n\t\t\telse renderJunction(listDiv, entry, itemOpts)\n\t\t}\n\n\t\tlistDiv\n\t\t\t.append('div')\n\t\t\t.style('font-size', '.7em')\n\t\t\t.style('margin-top', '10px')\n\t\t\t.style('opacity', 0.7)\n\t\t\t.text('Select additional junctions from genome browser.')\n\t}\n\trenderList()\n}\n\nfunction renderJunction(holder, entry: JunctionCustomTerm, opts) {\n\tconst choice = holder.append('div')\n\tchoice\n\t\t.append('div')\n\t\t.attr('class', 'ts_pill sja_filter_tag_btn sja_tree_click_term')\n\t\t.style('display', 'inline-block')\n\t\t.style('border-radius', '6px')\n\t\t.style('margin', '1px 0')\n\t\t.text(entry.tw.term.name)\n\t\t.on('click', () => opts.callback(entry.tw.term))\n\taddDeleteButton(choice, entry, opts)\n}\n\nfunction renderJunctionEvent(holder, fractionDiv, entry: JunctionCustomTerm, opts) {\n\tconst eventHolder = holder.append('div')\n\tconst pillRow = eventHolder.append('div')\n\tpillRow\n\t\t.append('div')\n\t\t.attr('class', 'ts_pill sja_filter_tag_btn sja_tree_click_term')\n\t\t.style('display', 'inline-block')\n\t\t.style('border-radius', '6px')\n\t\t.style('margin', '1px 0')\n\t\t.text(entry.eventlabel!)\n\t\t.on('click', () => selectJunctionEvent(holder, fractionDiv, entry, opts))\n\taddDeleteButton(pillRow, entry, opts)\n\teventHolder\n\t\t.append('div')\n\t\t.style('margin-left', '10px')\n\t\t.style('font-size', '.7em')\n\t\t.selectAll('div')\n\t\t.data(entry.tw.term.termlst, term => term.id)\n\t\t.enter()\n\t\t.append('div')\n\t\t.text(term => term.name)\n}\n\nfunction selectJunctionEvent(listDiv, fractionDiv, entry: JunctionCustomTerm, opts) {\n\tconst isStaged = mayRenderFractionSelection({\n\t\tterm: entry.tw.term,\n\t\tselectionMode: opts.termCollectionSelectionMode,\n\t\tlistDiv,\n\t\tfractionDiv,\n\t\tcallback: tw => opts.callback(tw)\n\t})\n\tif (!isStaged) opts.callback(entry.tw.term)\n}\n\nfunction addDeleteButton(holder, entry: JunctionCustomTerm, opts) {\n\tholder\n\t\t.append('button')\n\t\t.attr('data-testid', 'sjpp-junction-delete')\n\t\t.style('margin-left', '4px')\n\t\t.attr('aria-label', `Delete ${entry.name}`)\n\t\t.text('\u00D7')\n\t\t.on('click', async () => {\n\t\t\tawait opts.app.vocabApi.deleteCustomTermById(entry.id)\n\t\t\topts.renderList()\n\t\t})\n}\n\n/** A copy of a picked junction term, or of a splice event's termCollection, read for the chosen sample\n * types. A collection's member junctions get them too, since the server reads each member as a junction\n * term of its own. The caller leaves a term unchanged for no choice or a choice of every sample type. Like a methylation region term, the name says which\n * sample types, so that the same junction read for two of them is told apart where a plot labels terms\n * by name. */\nfunction withSampleTypes(term: any, termSampleTypes: { sampleTypes?: number[]; sampleTypeLabel?: string }) {\n\tconst { sampleTypes, sampleTypeLabel } = termSampleTypes\n\tconst t = { ...term, sampleTypes, sampleTypeLabel }\n\tt.name = term.name + getTermLabelSuffix(t)\n\tif (Array.isArray(term.termlst)) t.termlst = term.termlst.map(m => ({ ...m, sampleTypes }))\n\treturn t\n}\n"],
|
|
5
|
+
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6
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7
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