@sjcrh/proteinpaint-client 2.226.0 → 2.227.1

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (949) hide show
  1. package/dist/2dmaf-75YAQQ3P.js +1362 -0
  2. package/dist/AggMatrixInput-KYDS23KP.js +402 -0
  3. package/dist/AggregateMatrix-XGGF6KBX.js +37 -0
  4. package/dist/AppHeader-CNY5RTJN.js +826 -0
  5. package/dist/BoxPlot-OQIJJO66.js +1247 -0
  6. package/dist/CorrelationVolcano-QN5D37V7.js +613 -0
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  8. package/dist/Cuminc-J6DONJTA.js +1217 -0
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  843. /package/dist/{matrix-YBL4FZYJ.js.map → matrix-EB7YOLMN.js.map} +0 -0
  844. /package/dist/{matrix.cells-45ZFADK5.js.map → matrix.cells-A5E63KDN.js.map} +0 -0
  845. /package/dist/{matrix.config-QTBIRXKU.js.map → matrix.config-GSW2WJM4.js.map} +0 -0
  846. /package/dist/{matrix.data-WAMOLSKW.js.map → matrix.data-R4FW2PQH.js.map} +0 -0
  847. /package/dist/{matrix.groups-RXFXZABD.js.map → matrix.groups-3UH2KOIY.js.map} +0 -0
  848. /package/dist/{matrix.integration.spec-JZDZRVOK.js.map → matrix.integration.spec-R32TIABT.js.map} +0 -0
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  850. /package/dist/{matrix.layout-WWPRXXHX.js.map → matrix.layout-FD275D3P.js.map} +0 -0
  851. /package/dist/{matrix.legend-4MCMVVKO.js.map → matrix.legend-SE7SQTNN.js.map} +0 -0
  852. /package/dist/{matrix.renderers-JQTUODDS.js.map → matrix.renderers-RK2BRCHZ.js.map} +0 -0
  853. /package/dist/{matrix.serieses-3IDRKSGO.js.map → matrix.serieses-BEZCQDLJ.js.map} +0 -0
  854. /package/dist/{matrix.sort-EAWOB56R.js.map → matrix.sort-KRNS4VPF.js.map} +0 -0
  855. /package/dist/{matrix.sort.unit.spec-FOWLULHA.js.map → matrix.sort.unit.spec-LZG3GOXM.js.map} +0 -0
  856. /package/dist/{matrix.sorterUi.unit.spec-U5CQDTMX.js.map → matrix.sorterUi.unit.spec-RR2KK4R5.js.map} +0 -0
  857. /package/dist/{matrix.unit.spec-VTLD4EOZ.js.map → matrix.unit.spec-3PK6LUNE.js.map} +0 -0
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  859. /package/dist/{mds.samplescatterplot-PTWA2V6E.js.map → mds.samplescatterplot-WGQ7A7UC.js.map} +0 -0
  860. /package/dist/{mds.survivalplot-XVZ66GP5.js.map → mds.survivalplot-ZEGSEJO2.js.map} +0 -0
  861. /package/dist/{multivalue-2H7QX7MG.js.map → multivalue-DKUQCROX.js.map} +0 -0
  862. /package/dist/{numericDictTermCluster-EHCDRT6J.js.map → numericDictTermCluster-IFIEM3E4.js.map} +0 -0
  863. /package/dist/{oncomatrix-RZLZUC32.js.map → oncomatrix-WSPJAWHW.js.map} +0 -0
  864. /package/dist/{oncomatrix.spec-Z5UQGTW2.js.map → oncomatrix.spec-LDWTZ7LO.js.map} +0 -0
  865. /package/dist/{plot.2dvaf-IRBZBJ6B.js.map → plot.2dvaf-N333YSMC.js.map} +0 -0
  866. /package/dist/{plot.app-I23IAZ3Z.js.map → plot.app-HU5RQS5I.js.map} +0 -0
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  868. /package/dist/{plot.boxplot-VBWU7DUG.js.map → plot.boxplot-C4OXCRFB.js.map} +0 -0
  869. /package/dist/{plot.brainImaging-HDJMEMTK.js.map → plot.brainImaging-A6FEKFEA.js.map} +0 -0
  870. /package/dist/{plot.disco-5BVG3WMT.js.map → plot.disco-VDL7YKRX.js.map} +0 -0
  871. /package/dist/{plot.ssgq-S3BKXJMW.js.map → plot.ssgq-OII7PFPG.js.map} +0 -0
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  873. /package/dist/{polar2-PYLEVG7E.js.map → polar2-6KR2KX5D.js.map} +0 -0
  874. /package/dist/{profileForms-CI2YYD3Y.js.map → profileForms-YJDJIBSY.js.map} +0 -0
  875. /package/dist/{profilePlot-UCC4ZVHQ.js.map → profilePlot-U4U4AYMO.js.map} +0 -0
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  878. /package/dist/{pseudobulk-RUXGZ7OY.js.map → pseudobulk-WB6NXFJ6.js.map} +0 -0
  879. /package/dist/{qualitative-3AVR4GRX.js.map → qualitative-CQUBCCGT.js.map} +0 -0
  880. /package/dist/{qualitative-5QNBKDOZ.js.map → qualitative-QQ3CWFVP.js.map} +0 -0
  881. /package/dist/{radar2-AOYMS54Y.js.map → radar2-FNC67FNX.js.map} +0 -0
  882. /package/dist/{radarFacility2-PP2MAXIP.js.map → radarFacility2-3X77B4WP.js.map} +0 -0
  883. /package/dist/{render-ASLVKYEX.js.map → render-G5NCZTMW.js.map} +0 -0
  884. /package/dist/{report-UVYKDMQC.js.map → report-CR645KQ4.js.map} +0 -0
  885. /package/dist/{sampleView-6UHR7FSR.js.map → sampleView-6PG2HJZL.js.map} +0 -0
  886. /package/dist/{samplelst-ABC2CCNN.js.map → samplelst-FCQ7YPPQ.js.map} +0 -0
  887. /package/dist/{samplematrix-36UCHZLC.js.map → samplematrix-GXMN5QTS.js.map} +0 -0
  888. /package/dist/{sc-XLSAM725.js.map → sc-4ZTSQOXC.js.map} +0 -0
  889. /package/dist/{scatter-ADOBAOW2.js.map → scatter-2PUQU22I.js.map} +0 -0
  890. /package/dist/{scatter-ZNVLI627.js.map → scatter-ZSZTA37T.js.map} +0 -0
  891. /package/dist/{selectGenomeWithTklst-DPDBDYTR.js.map → selectGenomeWithTklst-XHWBEM2G.js.map} +0 -0
  892. /package/dist/{singleCellCellType-STVPYZD4.js.map → singleCellCellType-NP7Y4N6Z.js.map} +0 -0
  893. /package/dist/{singleCellCellType.unit.spec-ZLY37AXL.js.map → singleCellCellType.unit.spec-5I3FECB4.js.map} +0 -0
  894. /package/dist/{singleCellGeneExpression-PCGLU35S.js.map → singleCellGeneExpression-7RWH633E.js.map} +0 -0
  895. /package/dist/{singleCellGeneExpression.unit.spec-PSLKK362.js.map → singleCellGeneExpression.unit.spec-2X2BDTNO.js.map} +0 -0
  896. /package/dist/{singleCellNumericValue-SR3SJEOB.js.map → singleCellNumericValue-I6V4ME6T.js.map} +0 -0
  897. /package/dist/{singleCellNumericValue.unit.spec-PXVXJ4HJ.js.map → singleCellNumericValue.unit.spec-4HKAJXB3.js.map} +0 -0
  898. /package/dist/{singleCellPlot-JXB7M6OH.js.map → singleCellPlot-QRFR3AJH.js.map} +0 -0
  899. /package/dist/{singlecell-PH55NFRX.js.map → singlecell-AQEAB445.js.map} +0 -0
  900. /package/dist/{singlecell-EDSX56QO.js.map → singlecell-DX4EXNUV.js.map} +0 -0
  901. /package/dist/{snp-3VEYBTAQ.js.map → snp-2URSYPBL.js.map} +0 -0
  902. /package/dist/{snp.unit.spec-V7OB44US.js.map → snp.unit.spec-ZV2RCDT4.js.map} +0 -0
  903. /package/dist/{snplocus-HX67RBT5.js.map → snplocus-BB4I2QIP.js.map} +0 -0
  904. /package/dist/{snplst-H5YXCY33.js.map → snplst-A5S7CQEM.js.map} +0 -0
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  906. /package/dist/{spliceevent.exonskip.diagram-EYEL6BY6.js.map → spliceevent.exonskip.diagram-FKSR3JEL.js.map} +0 -0
  907. /package/dist/{spliceevent.noeventdiagram-64OEXK7U.js.map → spliceevent.noeventdiagram-G3JQUZKK.js.map} +0 -0
  908. /package/dist/{ssGSEA-3YWQH6KM.js.map → ssGSEA-KLMOSI53.js.map} +0 -0
  909. /package/dist/{ssGSEA.unit.spec-23V2IXP5.js.map → ssGSEA.unit.spec-HBALWLVB.js.map} +0 -0
  910. /package/dist/{stattable-GPSBCNYC.js.map → stattable-ZCMPIC3I.js.map} +0 -0
  911. /package/dist/{studyCatalog-W5PATRNY.js.map → studyCatalog-UZ4BSYY6.js.map} +0 -0
  912. /package/dist/{summarizeCnvGeneexp-YGI23QH5.js.map → summarizeCnvGeneexp-Z43GYKZB.js.map} +0 -0
  913. /package/dist/{summarizeGeneexpSurvival-KQ6OLWYR.js.map → summarizeGeneexpSurvival-4OHRMCFV.js.map} +0 -0
  914. /package/dist/{summarizeMutationCnv-XDHBNEPU.js.map → summarizeMutationCnv-EZXMLADC.js.map} +0 -0
  915. /package/dist/{summarizeMutationDiagnosis-VKIJRJ2Q.js.map → summarizeMutationDiagnosis-RPQP4TM5.js.map} +0 -0
  916. /package/dist/{summarizeMutationSurvival-57YKJGLE.js.map → summarizeMutationSurvival-LX4TRGJZ.js.map} +0 -0
  917. /package/dist/{summary-4WQOVIUF.js.map → summary-FZQVK5KR.js.map} +0 -0
  918. /package/dist/{summary.integration.spec-FRNWBU7F.js.map → summary.integration.spec-46T65LR5.js.map} +0 -0
  919. /package/dist/{summaryInput-X7DS2YA7.js.map → summaryInput-BHU7G5FC.js.map} +0 -0
  920. /package/dist/{sunburst-MSGTXYMM.js.map → sunburst-A5NS3KJQ.js.map} +0 -0
  921. /package/dist/{sunburst-3OEAQA3O.js.map → sunburst-R5X2C7FK.js.map} +0 -0
  922. /package/dist/{survival-5KC5CNZU.js.map → survival-MKW5J5ZH.js.map} +0 -0
  923. /package/dist/{survival-QXDS6N46.js.map → survival-N2NKMVOV.js.map} +0 -0
  924. /package/dist/{survival.integration.spec-PKENHLTZ.js.map → survival.integration.spec-K5FMOOTF.js.map} +0 -0
  925. /package/dist/{svgraph-VJLB7BBN.js.map → svgraph-3WRCJA5D.js.map} +0 -0
  926. /package/dist/{swimmer-R3DN7N36.js.map → swimmer-XV5KVWEM.js.map} +0 -0
  927. /package/dist/{table-YF5VORU6.js.map → table-XUGFZSGV.js.map} +0 -0
  928. /package/dist/{termCollection-KSHVOPS5.js.map → termCollection-23ZRHZHF.js.map} +0 -0
  929. /package/dist/{termCollection-3KGLZFDW.js.map → termCollection-NWTAUSSW.js.map} +0 -0
  930. /package/dist/{termCollection.unit.spec-HTBDG5PL.js.map → termCollection.unit.spec-WE3JMSUI.js.map} +0 -0
  931. /package/dist/{termCollectionFractionSelection-MK4NKWUX.js.map → termCollectionFractionSelection-5FLFLMIY.js.map} +0 -0
  932. /package/dist/{termCollectionFractionSelection.unit.spec-AMF32FDN.js.map → termCollectionFractionSelection.unit.spec-CCFGGXAA.js.map} +0 -0
  933. /package/dist/{tk-Z54DOECH.js.map → tk-F3TSB4IB.js.map} +0 -0
  934. /package/dist/{tp.ui-M4TZVT53.js.map → tp.ui-4QDX3FGM.js.map} +0 -0
  935. /package/dist/{tvs.categorical-HY3BWCZR.js.map → tvs.categorical-24OT3XZI.js.map} +0 -0
  936. /package/dist/{tvs.condition-Y36TRIX4.js.map → tvs.condition-X4SXCVGN.js.map} +0 -0
  937. /package/dist/{tvs.dt-XKVJZP7Y.js.map → tvs.dt-FRBJRSWI.js.map} +0 -0
  938. /package/dist/{tvs.dtcnv.categorical-OMRZR4Y7.js.map → tvs.dtcnv.categorical-4RRSO735.js.map} +0 -0
  939. /package/dist/{tvs.dtcnv.continuous-AGYOBI5K.js.map → tvs.dtcnv.continuous-HXY2PBUA.js.map} +0 -0
  940. /package/dist/{tvs.dtfusion-2JX5Y2IH.js.map → tvs.dtfusion-67LXBQA4.js.map} +0 -0
  941. /package/dist/{tvs.dtitd-SDSLBBWC.js.map → tvs.dtitd-MCJZCNV2.js.map} +0 -0
  942. /package/dist/{tvs.dtsnvindel-LI7K464K.js.map → tvs.dtsnvindel-K5YIIBQJ.js.map} +0 -0
  943. /package/dist/{tvs.dtsv-VRCLX7QY.js.map → tvs.dtsv-RP7FUB2N.js.map} +0 -0
  944. /package/dist/{tvs.multivalue-4OTY6J2S.js.map → tvs.multivalue-CROMWUCP.js.map} +0 -0
  945. /package/dist/{tvs.numeric-CDATYOR2.js.map → tvs.numeric-IYYYV6ZJ.js.map} +0 -0
  946. /package/dist/{tvs.samplelst-76JOJG2M.js.map → tvs.samplelst-5DXKRFYM.js.map} +0 -0
  947. /package/dist/{tvs.survival-WTFJOKIZ.js.map → tvs.survival-W5RXODBT.js.map} +0 -0
  948. /package/dist/{tvs.termCollection-QQXAS7PE.js.map → tvs.termCollection-OSJYIWDX.js.map} +0 -0
  949. /package/dist/{vocabulary-6ACAEFTL.js.map → vocabulary-HTRYJUD7.js.map} +0 -0
@@ -0,0 +1,348 @@
1
+ import {
2
+ matchesGvQueryEntry
3
+ } from "./chunk-CFYWQJ7F.js";
4
+ import {
5
+ mclass
6
+ } from "./chunk-2N345NXD.js";
7
+
8
+ // ../shared/utils/dist/src/termCollection.js
9
+ function validateTermCollectionTerm(term) {
10
+ if (!Array.isArray(term?.termlst) || !term.termlst.length)
11
+ throw new Error("termCollection requires nonempty term.termlst[]");
12
+ const memberIds = /* @__PURE__ */ new Set();
13
+ const types = /* @__PURE__ */ new Set();
14
+ for (const t of term.termlst) {
15
+ if (typeof t.id != "string" || !t.id) throw new Error("member term id not non-empty string");
16
+ if (typeof t.type != "string" || !t.type) throw new Error("member term type not non-empty string");
17
+ if (memberIds.has(t.id)) throw new Error(`duplicate member term id '${t.id}'`);
18
+ memberIds.add(t.id);
19
+ types.add(t.type == "integer" || t.type == "float" ? "numDict" : t.type);
20
+ }
21
+ if (types.size > 1) throw new Error("termCollection.termlst[] not allowed to mix multiple term types");
22
+ return memberIds;
23
+ }
24
+ function validateFractionMembers(numerators, denominators, memberIds) {
25
+ if (!Array.isArray(denominators) || !denominators.length) throw new Error("fraction requires nonempty denominators[]");
26
+ if (!Array.isArray(numerators) || !numerators.length) throw new Error("fraction requires nonempty numerators[]");
27
+ if (new Set(denominators).size !== denominators.length) throw new Error("fraction denominators[] contains duplicates");
28
+ if (new Set(numerators).size !== numerators.length) throw new Error("fraction numerators[] contains duplicates");
29
+ for (const id of denominators) {
30
+ if (typeof id != "string" || !id) throw new Error("fraction denominator id not non-empty string");
31
+ if (!memberIds.has(id)) throw new Error(`fraction denominator '${id}' is not a collection member`);
32
+ }
33
+ for (const id of numerators) {
34
+ if (typeof id != "string" || !id) throw new Error("fraction numerator id not non-empty string");
35
+ if (!denominators.includes(id)) throw new Error(`fraction numerator '${id}' is not included in denominators[]`);
36
+ }
37
+ }
38
+ var FRACTION_TW_TYPE = "TermCollectionTWFraction";
39
+ function isFractionTw(tw) {
40
+ return tw?.type === FRACTION_TW_TYPE && tw?.term?.type === "termCollection";
41
+ }
42
+ function getFractionTvsTerm(tw) {
43
+ if (!isFractionTw(tw)) throw new Error("not a fraction termCollection tw");
44
+ const term = structuredClone(tw.term);
45
+ const memberIds = term.termlst?.length ? validateTermCollectionTerm(term) : new Set(term.termIds || []);
46
+ const denominators = tw.q?.denominators?.length ? [...tw.q.denominators] : [...memberIds];
47
+ const numerators = tw.q?.numerators?.length ? [...tw.q.numerators] : [...denominators];
48
+ validateFractionMembers(numerators, denominators, memberIds);
49
+ term.numerators = numerators;
50
+ term.denominators = denominators;
51
+ return term;
52
+ }
53
+ function validateTermCollectionFraction(q, term) {
54
+ const memberIds = validateTermCollectionTerm(term);
55
+ validateFractionMembers(q?.numerators, q?.denominators, memberIds);
56
+ if (q.mode === "discrete" && q.type !== "regular-bin" && q.type !== "custom-bin")
57
+ throw new Error("discrete fraction termCollection requires regular-bin or custom-bin q.type");
58
+ }
59
+
60
+ // ../shared/utils/dist/src/filter.js
61
+ function getFilteredSamples(sampleAnno, filter) {
62
+ setDatasetAnnotations(filter);
63
+ const samples = /* @__PURE__ */ new Set();
64
+ for (const anno of sampleAnno) {
65
+ if (samples.has(anno.sample)) continue;
66
+ const data = anno.s || anno.data;
67
+ if (data && sample_match_termvaluesetting(data, filter)) {
68
+ samples.add(anno.sample);
69
+ }
70
+ }
71
+ return samples;
72
+ }
73
+ function sample_match_termvaluesetting(row, filter, _term = null, sample = null) {
74
+ const lst = filter.type == "tvslst" ? filter.lst : [filter];
75
+ let numberofmatchedterms = 0;
76
+ for (const item of lst) {
77
+ if ("type" in item && item.type == "tvslst") {
78
+ if (sample_match_termvaluesetting(row, item, _term, sample)) {
79
+ numberofmatchedterms++;
80
+ }
81
+ } else {
82
+ const itemCopy = JSON.parse(JSON.stringify(item));
83
+ const t = itemCopy.tvs;
84
+ if (_term && t.term) {
85
+ if (!(_term.name == t.term.name && _term.type == t.term.type)) {
86
+ numberofmatchedterms++;
87
+ continue;
88
+ }
89
+ }
90
+ let samplevalue;
91
+ if (_term && !t.term) {
92
+ if (t.term$type && t.term$type !== _term.type) {
93
+ numberofmatchedterms++;
94
+ continue;
95
+ }
96
+ t.term = _term;
97
+ samplevalue = typeof row === "object" && t.term.id in row ? row[t.term.id] : row;
98
+ } else if (sample && t.term.$id) {
99
+ samplevalue = sample[t.term.$id].value;
100
+ } else {
101
+ samplevalue = t.term.id in row ? row[t.term.id] : row;
102
+ }
103
+ setDatasetAnnotations(itemCopy);
104
+ let thistermmatch;
105
+ if (t.term.type == "categorical") {
106
+ if (samplevalue === void 0) continue;
107
+ thistermmatch = t.valueset.has(samplevalue);
108
+ } else if (t.term.type == "integer" || t.term.type == "float") {
109
+ if (samplevalue === void 0) continue;
110
+ for (const range of t.ranges) {
111
+ if ("value" in range) {
112
+ thistermmatch = samplevalue === range.value;
113
+ if (thistermmatch) break;
114
+ } else if (samplevalue == range.name) {
115
+ thistermmatch = true;
116
+ break;
117
+ } else {
118
+ if (t.term.values) {
119
+ const v = t.term.values[samplevalue.toString()];
120
+ if (v && v.uncomputable) {
121
+ continue;
122
+ }
123
+ }
124
+ let left, right;
125
+ if (range.startunbounded) {
126
+ left = true;
127
+ } else if ("start" in range) {
128
+ if (range.startinclusive) {
129
+ left = samplevalue >= range.start;
130
+ } else {
131
+ left = samplevalue > range.start;
132
+ }
133
+ }
134
+ if (range.stopunbounded) {
135
+ right = true;
136
+ } else if ("stop" in range) {
137
+ if (range.stopinclusive) {
138
+ right = samplevalue <= range.stop;
139
+ } else {
140
+ right = samplevalue < range.stop;
141
+ }
142
+ }
143
+ thistermmatch = left && right;
144
+ }
145
+ if (thistermmatch) break;
146
+ }
147
+ } else if (t.term.type == "condition") {
148
+ const key = getPrecomputedKey(t);
149
+ const anno = samplevalue && samplevalue[key];
150
+ if (anno) {
151
+ thistermmatch = Array.isArray(anno) ? t.values.find((d) => anno.includes(d.key)) : t.values.find((d) => d.key == anno);
152
+ }
153
+ } else if (t.term.type == "geneVariant") {
154
+ const svalues = samplevalue.values || [samplevalue];
155
+ for (const sv of svalues) {
156
+ thistermmatch = t.values.find(
157
+ (v) => v.dt == sv.dt && (!v.origin || sv.origin == v.origin) && (!v.mclasslst || v.mclasslst.includes(sv.class))
158
+ ) && true;
159
+ if (thistermmatch) break;
160
+ }
161
+ } else {
162
+ throw "unknown term type [sample_match_termvaluesetting() shared/utils/src/filter.ts]";
163
+ }
164
+ if (t.isnot) {
165
+ thistermmatch = !thistermmatch;
166
+ }
167
+ if (thistermmatch) numberofmatchedterms++;
168
+ }
169
+ if (filter.join == "or") {
170
+ if (numberofmatchedterms && filter.in) return true;
171
+ if (!numberofmatchedterms && !filter.in) return true;
172
+ }
173
+ }
174
+ if (!("in" in filter)) filter.in = true;
175
+ return filter.in == (numberofmatchedterms == lst.length);
176
+ }
177
+ function setDatasetAnnotations(item, ds = null) {
178
+ if (item.type == "tvslst") {
179
+ for (const subitem of item.lst) {
180
+ setDatasetAnnotations(subitem, ds);
181
+ }
182
+ } else {
183
+ if (ds && typeof ds.setAnnoByTermId == "function") {
184
+ ds.setAnnoByTermId(item.tvs.term.id);
185
+ }
186
+ if (item.tvs.term.type == "categorical") {
187
+ const tvsAny = item.tvs;
188
+ tvsAny.valueset = new Set(tvsAny.values.map((i) => i.key));
189
+ }
190
+ }
191
+ }
192
+ function getPrecomputedKey(q) {
193
+ const precomputedKey = q.bar_by_children && q.value_by_max_grade ? "childrenAtMaxGrade" : q.bar_by_children && q.value_by_most_recent ? "childrenAtMostRecent" : q.bar_by_children && q.value_by_computable_grade ? "children" : q.bar_by_grade && q.value_by_max_grade ? "maxGrade" : q.bar_by_grade && q.value_by_most_recent ? "mostRecentGrades" : q.bar_by_grade && q.value_by_computable_grade ? "computableGrades" : "";
194
+ if (!precomputedKey) throw `unknown condition term bar_by_* and/or value_by_*`;
195
+ return precomputedKey;
196
+ }
197
+ function getWrappedTvslst(lst = [], join = "", $id = null) {
198
+ const filter = {
199
+ type: "tvslst",
200
+ in: true,
201
+ join,
202
+ lst
203
+ };
204
+ if ($id !== null) filter.$id = $id;
205
+ return filter;
206
+ }
207
+ function getTvsDenominators(term) {
208
+ if (Array.isArray(term?.denominators) && term.denominators.length) return term.denominators;
209
+ return (term?.termlst || []).map((t) => t.id);
210
+ }
211
+ function validateTermCollectionTvs(term) {
212
+ const memberIds = validateTermCollectionTerm(term);
213
+ if (!term.numerators) return;
214
+ validateFractionMembers(term.numerators, getTvsDenominators(term), memberIds);
215
+ }
216
+
217
+ // ../shared/utils/dist/src/geneVariantFilter.js
218
+ var statusClasses = /* @__PURE__ */ new Set(["WT", "Blank"]);
219
+ function unsupported(what) {
220
+ return `tw.q.variantFilter does not support ${what}, which qualifies a sample rather than an individual variant. Use a groupset (q.type='custom-groupset') for a sample-level filter.`;
221
+ }
222
+ function validateVariantFilter(filter, term) {
223
+ if (!filter) return;
224
+ if (filter.type != "tvslst") throw `tw.q.variantFilter.type must be 'tvslst'`;
225
+ if (!Array.isArray(filter.lst) || !filter.lst.length) throw "tw.q.variantFilter.lst[] is empty";
226
+ if (filter.lst.length > 1 && filter.join != "and" && filter.join != "or")
227
+ throw `tw.q.variantFilter.join must be 'and' or 'or' when lst[] has more than one item`;
228
+ const dts = term?.childTerms?.length ? new Set(term.childTerms.map((t) => t.dt)) : null;
229
+ for (const item of filter.lst) {
230
+ if (item.type == "tvslst") {
231
+ validateVariantFilter(item, term);
232
+ continue;
233
+ }
234
+ if (item.type != "tvs") throw `unexpected tw.q.variantFilter item.type='${item.type}'`;
235
+ const tvs = item.tvs;
236
+ if (!tvs) throw "missing tvs of a tw.q.variantFilter item";
237
+ if (!Number.isInteger(tvs.term?.dt)) throw "tw.q.variantFilter tvs.term must be a dt term, with an integer .dt";
238
+ if (dts && !dts.has(tvs.term.dt))
239
+ throw `tw.q.variantFilter tvs.term.dt=${tvs.term.dt} is not a dt of term '${term.name}'`;
240
+ if (!Array.isArray(tvs.values) || !tvs.values.length) throw "tw.q.variantFilter tvs.values[] is empty";
241
+ for (const v of tvs.values) {
242
+ if (!v.key) throw "a tw.q.variantFilter tvs.values[] entry is missing .key";
243
+ if (statusClasses.has(v.key))
244
+ throw `tw.q.variantFilter cannot select the '${v.key}' class, which is a testing status and not a variant`;
245
+ if (v.partnerBreakpointRange) throw unsupported("partnerBreakpointRange");
246
+ }
247
+ if (tvs.genotype && tvs.genotype != "variant") throw unsupported(`genotype='${tvs.genotype}'`);
248
+ if (tvs.mcount && tvs.mcount != "any") throw unsupported(`mcount='${tvs.mcount}'`);
249
+ if (tvs.mafFilter) throw unsupported("mafFilter");
250
+ if (tvs.continuousCnv) throw unsupported("continuousCnv");
251
+ if (tvs.selfBreakpointRange) throw unsupported("selfBreakpointRange");
252
+ }
253
+ }
254
+ function getTvsOrigins(tvs) {
255
+ return tvs.origins?.length ? tvs.origins : void 0;
256
+ }
257
+ function getFilterScope(filter, scope = /* @__PURE__ */ new Set()) {
258
+ for (const item of filter.lst) {
259
+ if (item.type == "tvslst") {
260
+ getFilterScope(item, scope);
261
+ continue;
262
+ }
263
+ const origins = getTvsOrigins(item.tvs);
264
+ if (origins) for (const origin of origins) scope.add(`${item.tvs.term.dt}:${origin}`);
265
+ else scope.add(`${item.tvs.term.dt}:*`);
266
+ }
267
+ return scope;
268
+ }
269
+ function isInScope(v, scope) {
270
+ return scope.has(`${v.dt}:*`) || scope.has(`${v.dt}:${v.origin || ""}`);
271
+ }
272
+ function matchTvs(v, tvs) {
273
+ let match = false;
274
+ const origins = getTvsOrigins(tvs);
275
+ if (v.dt == tvs.term.dt && (!origins || origins.includes(v.origin))) {
276
+ match = tvs.values.some((e) => e.key == v.class && (!e.mname || e.mname == v.mname && matchesGvQueryEntry(e, v)));
277
+ }
278
+ return tvs.isnot ? !match : match;
279
+ }
280
+ function matchFilter(v, filter) {
281
+ const lst = filter.type == "tvslst" ? filter.lst : [filter];
282
+ let numMatched = 0;
283
+ for (const item of lst) {
284
+ const matched = item.type == "tvslst" ? matchFilter(v, item) : matchTvs(v, item.tvs);
285
+ if (matched) numMatched++;
286
+ if (filter.join == "or" && numMatched) break;
287
+ }
288
+ const pass = filter.join == "or" ? numMatched > 0 : numMatched == lst.length;
289
+ return filter.in === false ? !pass : pass;
290
+ }
291
+ function filterVariantValues(values, filter) {
292
+ if (!filter || !values) return values;
293
+ const scope = getFilterScope(filter);
294
+ const kept = [];
295
+ const annotated = /* @__PURE__ */ new Set();
296
+ const dropped = /* @__PURE__ */ new Map();
297
+ for (const v of values) {
298
+ if (!isInScope(v, scope)) continue;
299
+ const key = `${v.dt}:${v.origin || ""}`;
300
+ if (statusClasses.has(v.class) || matchFilter(v, filter)) {
301
+ kept.push(v);
302
+ annotated.add(key);
303
+ } else if (!dropped.has(key)) {
304
+ dropped.set(key, v);
305
+ }
306
+ }
307
+ for (const [key, v] of dropped) {
308
+ if (annotated.has(key)) continue;
309
+ const wt = { dt: v.dt, class: "WT", label: mclass.WT.label };
310
+ if (v.gene) wt.gene = v.gene;
311
+ if (v.origin) wt.origin = v.origin;
312
+ kept.push(wt);
313
+ }
314
+ return kept;
315
+ }
316
+ function variantFilterLabel(filter, mclassOverride, maxItems = 3) {
317
+ if (!filter) return "";
318
+ const entries = [];
319
+ collect(filter, false);
320
+ function collect(f, negated) {
321
+ const flipped = f.in === false ? !negated : negated;
322
+ for (const item of f.lst) {
323
+ if (item.type == "tvslst") collect(item, flipped);
324
+ else if (flipped === !!item.tvs.isnot) entries.push(...item.tvs.values);
325
+ }
326
+ }
327
+ if (!entries.length) return "";
328
+ const classes = mclass;
329
+ const names = [
330
+ ...new Set(entries.map((e) => e.mname || mclassOverride?.[e.key]?.label || classes[e.key]?.label || e.key))
331
+ ];
332
+ return names.length > maxItems ? `${names.slice(0, maxItems).join("/")}\u2026` : names.join("/");
333
+ }
334
+
335
+ export {
336
+ isFractionTw,
337
+ getFractionTvsTerm,
338
+ validateTermCollectionFraction,
339
+ getFilteredSamples,
340
+ sample_match_termvaluesetting,
341
+ getWrappedTvslst,
342
+ getTvsDenominators,
343
+ validateTermCollectionTvs,
344
+ validateVariantFilter,
345
+ filterVariantValues,
346
+ variantFilterLabel
347
+ };
348
+ //# sourceMappingURL=chunk-2IAELUCN.js.map
@@ -0,0 +1,195 @@
1
+ import {
2
+ sample_match_termvaluesetting
3
+ } from "./chunk-DOC3HBOV.js";
4
+ import {
5
+ isDictionaryType
6
+ } from "./chunk-CFYWQJ7F.js";
7
+ import {
8
+ __export
9
+ } from "./chunk-HS5PO5ZQ.js";
10
+
11
+ // plots/matrix/matrix.data.js
12
+ var matrix_data_exports = {};
13
+ __export(matrix_data_exports, {
14
+ applyLegendValueFilter: () => applyLegendValueFilter,
15
+ getMatrixRequestOpts: () => getMatrixRequestOpts,
16
+ mayRequireToken: () => mayRequireToken,
17
+ setData: () => setData
18
+ });
19
+ function mayRequireToken(tokenMessage = "") {
20
+ const message = tokenMessage || this.state.tokenVerificationMessage;
21
+ if (!message && this.state.hasVerifiedToken) {
22
+ this.dom.errdiv.style("display", "none").html();
23
+ this.dom.controls.style("display", this.opts.controls ? "inline-block" : "");
24
+ this.dom.svg.style("display", "");
25
+ return false;
26
+ } else {
27
+ this.dom.errdiv.style("display", "").html(message || "Requires login");
28
+ this.dom.controls.style("display", "none");
29
+ this.dom.svg.style("display", "none");
30
+ return true;
31
+ }
32
+ }
33
+ function getMatrixRequestOpts(state, config) {
34
+ const terms = [];
35
+ const termgroups = this.chartType == "hierCluster" ? config.termgroups.filter((grp) => grp.type != "hierCluster") : config.termgroups;
36
+ for (const grp of termgroups) {
37
+ terms.push(...getNormalizedTwLstCopy(grp.lst));
38
+ }
39
+ if (config.divideBy) terms.push(normalizeTwForRequest(structuredClone(config.divideBy)));
40
+ const opts = {
41
+ terms,
42
+ filter: state.filter,
43
+ filter0: state.filter0,
44
+ maxGenes: state.config.settings.matrix.maxGenes,
45
+ /*********** quick fix
46
+ when the flag is true, set artificially large number to ensure all genes are sent in one query
47
+ this avoids changing getAnnotatedSampleData()
48
+ additional non-matrix app that calls getAnnotatedSampleData will NEED THE SAME FIX
49
+ */
50
+ termsPerRequest: this.app.vocabApi.termdbConfig.queries?.snvindel?.byisoform?.processTwsInOneQuery ? 1e3 : 1
51
+ };
52
+ if (this.chartType != "hierCluster" && config.settings.matrix.mapChildren2Root) opts.mapChildren2Root = true;
53
+ if (this.chartType == "hierCluster") {
54
+ opts.isHierCluster = 1;
55
+ }
56
+ return opts;
57
+ }
58
+ function getNormalizedTwLstCopy(twlst) {
59
+ const lst = [];
60
+ for (const tw of twlst) {
61
+ if (tw.type && tw.constructor.name != "Object") lst.push(tw);
62
+ else lst.push(normalizeTwForRequest(tw));
63
+ }
64
+ lst.forEach(normalizeTwForRequest);
65
+ lst.sort(sortTwLst);
66
+ return lst;
67
+ }
68
+ function normalizeTwForRequest(_tw) {
69
+ const tw = structuredClone(_tw);
70
+ if (!tw?.term) return;
71
+ delete tw.term.category2samplecount;
72
+ if (isDictionaryType(tw.term.type) && tw.term.type !== "samplelst") delete tw.term.values;
73
+ return tw;
74
+ }
75
+ function sortTwLst(twa, twb) {
76
+ const a = twa?.$id || twa.term?.id || twa?.term?.name;
77
+ const b = twb?.$id || twb.term?.id || twb?.term?.name;
78
+ return a < b ? -1 : 1;
79
+ }
80
+ async function setData(_data) {
81
+ const opts = this.currRequestOpts?.matrix || this.getMatrixRequestOpts(this.state, this.config);
82
+ this.numTerms = opts.terms.length;
83
+ opts.loadingDiv = this.chartType != "hierCluster" && this.dom.loadingDiv;
84
+ opts.signal = this.api.getAbortSignal();
85
+ const data = await this.app.vocabApi.getAnnotatedSampleData(opts, _data);
86
+ this.data = data;
87
+ this.origData = structuredClone(this.data);
88
+ this.sampleIdMap = {};
89
+ for (const d of this.data.lst) {
90
+ this.sampleIdMap[d.sample] = d._ref_.label;
91
+ }
92
+ }
93
+ function applyLegendValueFilter() {
94
+ const self = this;
95
+ if (!self.config.legendValueFilter.lst.length && !self.config.legendGrpFilter.lst.length) return;
96
+ for (const grpFilter of self.config.legendGrpFilter.lst) {
97
+ if (grpFilter.dt) {
98
+ const filteredOutCats = /* @__PURE__ */ new Set();
99
+ for (const oneSampleData of self.origData.lst) {
100
+ for (const annoForOneTerm of Object.values(oneSampleData)) {
101
+ if (annoForOneTerm.values) {
102
+ const newValues = [];
103
+ for (const v of annoForOneTerm.values) {
104
+ if (!(grpFilter.dt.includes(v.dt) && (!grpFilter.origin || v.origin == grpFilter.origin))) {
105
+ newValues.push(v);
106
+ } else {
107
+ filteredOutCats.add(v.class);
108
+ }
109
+ }
110
+ annoForOneTerm.values = newValues;
111
+ }
112
+ }
113
+ }
114
+ grpFilter.filteredOutCats = [...filteredOutCats];
115
+ for (const oneSampleData of Object.values(self.origData.samples)) {
116
+ for (const annoForOneTerm of Object.values(oneSampleData)) {
117
+ if (annoForOneTerm.values)
118
+ annoForOneTerm.values = annoForOneTerm.values.filter(
119
+ (v) => !(grpFilter.dt.includes(v.dt) && (!grpFilter.origin || v.origin == grpFilter.origin))
120
+ );
121
+ }
122
+ }
123
+ }
124
+ }
125
+ const geneVariant$ids = Object.values(self.data.refs.byTermId).filter((v) => v.term?.type == "geneVariant").map((v) => v.$id);
126
+ const data = { samples: {}, lst: [], refs: self.data.refs };
127
+ const onlyHardFilter = structuredClone(self.config.legendValueFilter);
128
+ onlyHardFilter.lst = onlyHardFilter.lst.filter(
129
+ (l) => !l.tvs.legendFilterType || l.tvs.legendFilterType !== "geneVariant_soft"
130
+ );
131
+ for (const row of self.origData.lst) {
132
+ const include = sample_match_termvaluesetting(row, onlyHardFilter, geneVariant$ids);
133
+ if (include || self.chartType == "hierCluster") {
134
+ data.samples[row.sample] = row;
135
+ data.lst.push(row);
136
+ }
137
+ }
138
+ for (const valFilter of self.config.legendValueFilter.lst) {
139
+ if (valFilter.tvs.legendFilterType !== "geneVariant_soft") continue;
140
+ const tvsV = valFilter.tvs.values[0];
141
+ const filteredOutCats = /* @__PURE__ */ new Set();
142
+ for (const oneSampleData of data.lst) {
143
+ for (const annoForOneTerm of Object.values(oneSampleData)) {
144
+ if (annoForOneTerm.values) {
145
+ const newValues = [];
146
+ for (const v of annoForOneTerm.values) {
147
+ if (!(v.dt == tvsV.dt && (!tvsV.origin || v.origin == tvsV.origin) && tvsV.mclasslst.includes(v.class))) {
148
+ newValues.push(v);
149
+ } else {
150
+ filteredOutCats.add(v.class);
151
+ }
152
+ }
153
+ annoForOneTerm.values = newValues;
154
+ }
155
+ }
156
+ }
157
+ valFilter.filteredOutCats = [...filteredOutCats];
158
+ for (const oneSampleData of Object.values(data.samples)) {
159
+ for (const annoForOneTerm of Object.values(oneSampleData)) {
160
+ if (annoForOneTerm.values)
161
+ annoForOneTerm.values = annoForOneTerm.values.filter(
162
+ (v) => !(v.dt == tvsV.dt && (!tvsV.origin || v.origin == tvsV.origin) && tvsV.mclasslst.includes(v.class))
163
+ );
164
+ }
165
+ }
166
+ }
167
+ if (self.chartType !== "hierCluster" && geneVariant$ids.length && self.app.vocabApi.termdbConfig?.matrix?.removeEmptySamples)
168
+ remove_empty_sample(data, geneVariant$ids);
169
+ self.data = data;
170
+ }
171
+ function remove_empty_sample(data) {
172
+ for (const oneSampleData of data.lst) {
173
+ let removeSample = true;
174
+ for (const [key, annoForOneTerm] of Object.entries(oneSampleData)) {
175
+ if (!annoForOneTerm.values) continue;
176
+ const annoType = data.refs.byTermId[key].term.type;
177
+ if (annoType != "geneVariant") continue;
178
+ if (annoForOneTerm.values.length) removeSample = false;
179
+ }
180
+ if (removeSample) {
181
+ data.lst = data.lst.filter((dl) => dl.sample !== oneSampleData.sample);
182
+ delete data.samples[parseInt(oneSampleData.sample)];
183
+ }
184
+ }
185
+ return data;
186
+ }
187
+
188
+ export {
189
+ mayRequireToken,
190
+ getMatrixRequestOpts,
191
+ setData,
192
+ applyLegendValueFilter,
193
+ matrix_data_exports
194
+ };
195
+ //# sourceMappingURL=chunk-2W6U53AG.js.map
@@ -0,0 +1,96 @@
1
+ import {
2
+ keyupEnter,
3
+ require_debounce
4
+ } from "./chunk-CXCAQOFB.js";
5
+ import {
6
+ Menu
7
+ } from "./chunk-CNFTQSNE.js";
8
+ import {
9
+ dofetch,
10
+ dofetch3
11
+ } from "./chunk-VVWZ4BOI.js";
12
+ import {
13
+ __toESM
14
+ } from "./chunk-HS5PO5ZQ.js";
15
+
16
+ // src/gene.js
17
+ var import_debounce = __toESM(require_debounce(), 1);
18
+ var tip;
19
+ function gene_searchbox(p) {
20
+ if (!tip) {
21
+ tip = new Menu({ padding: "" });
22
+ tip.d.style("z-index", 1e3);
23
+ }
24
+ const input = p.div.append("input").attr("placeholder", "Search gene").style("width", p.width || "100px");
25
+ const printdiv = p.resultdiv || (p.tip ? p.tip.d : tip.d);
26
+ function fold() {
27
+ if (p.resultdiv) {
28
+ p.resultdiv.selectAll("*").remove();
29
+ } else if (p.tip) {
30
+ p.tip.hide();
31
+ } else {
32
+ tip.hide();
33
+ }
34
+ }
35
+ input.on("keyup", (event) => {
36
+ const str = event.target.value;
37
+ if (str.length <= 1) {
38
+ fold();
39
+ return;
40
+ }
41
+ if (keyupEnter(event)) {
42
+ const hitgene = printdiv.select(".sja_menuoption");
43
+ if (hitgene.size() > 0) {
44
+ p.callback(hitgene.text());
45
+ fold();
46
+ }
47
+ return;
48
+ }
49
+ debouncer();
50
+ });
51
+ input.node().focus();
52
+ function genesearch() {
53
+ dofetch("genelookup", { genome: p.genome, input: input.property("value") }).then((data) => {
54
+ if (data.error) throw data.error;
55
+ if (!data.hits) throw ".hits[] missing";
56
+ if (p.resultdiv) {
57
+ p.resultdiv.selectAll("*").remove();
58
+ } else if (p.tip) {
59
+ p.tip.clear().showunder(input.node());
60
+ } else {
61
+ tip.clear().showunder(input.node());
62
+ }
63
+ for (const name of data.hits) {
64
+ printdiv.append("div").attr("class", "sja_menuoption").text(name).on("click", () => {
65
+ p.callback(name);
66
+ fold();
67
+ });
68
+ }
69
+ }).catch((err) => {
70
+ printdiv.append("div").text(err.message || err);
71
+ if (err.stack) console.log(err.stack);
72
+ });
73
+ }
74
+ const debouncer = (0, import_debounce.debounce)(genesearch, 300);
75
+ }
76
+ function findgenemodel_bysymbol(genome, str) {
77
+ return dofetch3("genelookup", {
78
+ body: {
79
+ deep: 1,
80
+ input: str,
81
+ genome
82
+ }
83
+ }).then((data) => {
84
+ if (data.error) throw data.error;
85
+ if (!data.gmlst || data.gmlst.length == 0) return null;
86
+ return data.gmlst;
87
+ }).catch((e) => {
88
+ throw e;
89
+ });
90
+ }
91
+
92
+ export {
93
+ gene_searchbox,
94
+ findgenemodel_bysymbol
95
+ };
96
+ //# sourceMappingURL=chunk-3R6VYZYB.js.map