@sjcrh/proteinpaint-client 2.207.1 → 2.209.0
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/dist/2dmaf-VTMPVZGT.js +1367 -0
- package/dist/AggMatrixInput-CH3RQ2QC.js +406 -0
- package/dist/AggMatrixInput-CH3RQ2QC.js.map +7 -0
- package/dist/AggregateMatrix-DPCHUOMF.js +41 -0
- package/dist/AppHeader-RA7T467G.js +830 -0
- package/dist/BoxPlot-7Q7SMT26.js +1211 -0
- package/dist/CorrelationVolcano-YV4UHOAX.js +617 -0
- package/dist/CorrelationVolcano-YV4UHOAX.js.map +7 -0
- package/dist/Cuminc-ZN53C3MD.js +1219 -0
- package/dist/DE-BEWW5AIG.js +89 -0
- package/dist/DEinput-SJITUJF2.js +499 -0
- package/dist/DM-2LBNE4WE.js +90 -0
- package/dist/DifferentialAnalysis-WE4LBHEF.js +239 -0
- package/dist/DifferentialAnalysis-WE4LBHEF.js.map +7 -0
- package/dist/Disco-PTZQF7IM.js +3389 -0
- package/dist/Disco.UI-NBR67N5M.js +243 -0
- package/dist/DmrPlot-QROLI66S.js +362 -0
- package/dist/DmrPlot-QROLI66S.js.map +7 -0
- package/dist/GB-FEBSFX5U.js +1428 -0
- package/dist/GB-FEBSFX5U.js.map +7 -0
- package/dist/GSEA-KOXOVC5V.js +875 -0
- package/dist/GSEA-KOXOVC5V.js.map +7 -0
- package/dist/GeneExpInput-DYBK54HC.js +42 -0
- package/dist/Geomap-QRD2WZVL.js +84 -0
- package/dist/HicApp-VKET4QHD.js +2245 -0
- package/dist/IDCViewer-RLLTXGD7.js +10812 -0
- package/dist/NumBinaryEditor-GYHOYPQL.js +279 -0
- package/dist/NumBinaryEditor.unit.spec-E2HKBWOO.js +312 -0
- package/dist/NumContEditor-3V76ZSEY.js +105 -0
- package/dist/NumContEditor.unit.spec-RTT5Q5E5.js +164 -0
- package/dist/NumCustomBinEditor-O5DMPY7H.js +33 -0
- package/dist/NumCustomBinEditor.unit.spec-5LZBP2JL.js +397 -0
- package/dist/NumDiscreteEditor-DFOJ7AIH.js +170 -0
- package/dist/NumDiscreteEditor.unit.spec-PPJGEBFX.js +233 -0
- package/dist/NumRegularBinEditor-O6RDO32C.js +33 -0
- package/dist/NumRegularBinEditor.unit.spec-GOB3BF25.js +278 -0
- package/dist/NumSplineEditor-PUXJF2RW.js +210 -0
- package/dist/NumSplineEditor.unit.spec-4VOAAMOU.js +224 -0
- package/dist/NumericDensity-E6MH2THZ.js +33 -0
- package/dist/NumericDensity.unit.spec-IRPFBQUS.js +418 -0
- package/dist/NumericHandler-42RR54X3.js +34 -0
- package/dist/NumericHandler.unit.spec-YYOO7XVT.js +214 -0
- package/dist/ProteomeInput-4N2G6IFX.js +388 -0
- package/dist/Regression-LIWUWAGQ.js +1416 -0
- package/dist/Regression-LIWUWAGQ.js.map +7 -0
- package/dist/RunChart2-VAX5JGZY.js +749 -0
- package/dist/SC-UHBZ3HRO.js +1183 -0
- package/dist/SC-UHBZ3HRO.js.map +7 -0
- package/dist/Violin-V23VZR6B.js +1081 -0
- package/dist/Violin-V23VZR6B.js.map +7 -0
- package/dist/Volcano-64S4AW66.js +2443 -0
- package/dist/Volcano-64S4AW66.js.map +7 -0
- package/dist/Wsi-FOJCKDCP.js +629 -0
- package/dist/Wsi-FOJCKDCP.js.map +7 -0
- package/dist/adSandbox-CLMUYNC3.js +33 -0
- package/dist/animatedBubbleChart-GMLNYTQC.js +547 -0
- package/dist/app-2SFDRDN2.js +32 -0
- package/dist/app-QOZ36UR4.js +42 -0
- package/dist/app.js +14 -14
- package/dist/bam-LLAK7FVG.js +876 -0
- package/dist/barchart-SEC6VKQ2.js +42 -0
- package/dist/barchart2-D4FXZCTU.js +309 -0
- package/dist/block-XGK6TEGH.js +6250 -0
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- package/dist/block.init-UMRCAKCF.js +33 -0
- package/dist/block.mds.expressionrank-LFPJ52SX.js +354 -0
- package/dist/block.mds.geneboxplot-2QIEN6AH.js +823 -0
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- package/dist/block.tk.aicheck-5N6EGZ6F.js +278 -0
- package/dist/block.tk.ase-V3AJRYT6.js +360 -0
- package/dist/block.tk.bam-W6QOVVEU.js +1901 -0
- package/dist/block.tk.bedgraphdot-FKTPJZTH.js +379 -0
- package/dist/block.tk.bigwig.ui-Y3M2TDM2.js +206 -0
- package/dist/block.tk.hicstraw-3SWYTMFQ.js +818 -0
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- package/dist/block.tk.junction.textmatrixui-PWBLRGCO.js +194 -0
- package/dist/block.tk.ld-NTRJL5GA.js +94 -0
- package/dist/block.tk.menu-JIHSGGIO.js +1024 -0
- package/dist/block.tk.pgv-4Q6CY6QN.js +938 -0
- package/dist/brainImaging-MBI4XTTU.js +555 -0
- package/dist/brainRegions-YVTAESRP.js +217 -0
- package/dist/bubbleHeatmap-ZKTA3AIG.js +378 -0
- package/dist/cellTypeBubbleHeatmap-GJZNXDG4.js +278 -0
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- package/dist/cohort-GVAJTICQ.js +70 -0
- package/dist/condition-EGPNMM47.js +327 -0
- package/dist/controls-HBROSXHF.js +34 -0
- package/dist/controls.config-FWKV66TU.js +34 -0
- package/dist/correlation-CEHE66EC.js +95 -0
- package/dist/customdata.inputui-LFT3N5FD.js +284 -0
- package/dist/dataDownload-ZPAIAAE4.js +329 -0
- package/dist/databrowser.ui-W5JGFBE6.js +425 -0
- package/dist/dictionary-RBE2CIZI.js +113 -0
- package/dist/dnaMethylation-CX22TSRO.js +33 -0
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- package/dist/dofetch-6NAGX5EG.js +48 -0
- package/dist/e2pca-XDGPTEXL.js +344 -0
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- package/dist/expclust.gdc.spec-BMN2PTJX.js +302 -0
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- package/dist/geneExpClustering-NFH5FS3S.js +244 -0
- package/dist/geneExpression-XVOLNYVN.js +310 -0
- package/dist/geneExpression-ZP2VWHED.js +33 -0
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- /package/dist/{singlecell-BRF2HAV2.js.map → singlecell-BANNFGBS.js.map} +0 -0
- /package/dist/{singlecell-KVCJF2HI.js.map → singlecell-ZUTL5ZWE.js.map} +0 -0
- /package/dist/{ssGSEA-7RKWYZKX.js.map → snp-BHG4NVK4.js.map} +0 -0
- /package/dist/{snp.unit.spec-JF6KR2NT.js.map → snp.unit.spec-Q3AZHQRC.js.map} +0 -0
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- /package/dist/{spliceevent.a53ss.diagram-OSZZ2CF2.js.map → spliceevent.a53ss.diagram-UKRIP7EP.js.map} +0 -0
- /package/dist/{spliceevent.exonskip.diagram-AMA2D2OL.js.map → spliceevent.exonskip.diagram-CU777CXQ.js.map} +0 -0
- /package/dist/{spliceevent.noeventdiagram-RKTUXH5D.js.map → spliceevent.noeventdiagram-LGLXCF25.js.map} +0 -0
- /package/dist/{summarizeMutationDiagnosis-GCL4SRON.js.map → ssGSEA-BIEEKAKX.js.map} +0 -0
- /package/dist/{ssGSEA.unit.spec-XLCZHH7S.js.map → ssGSEA.unit.spec-YD4UDIRH.js.map} +0 -0
- /package/dist/{stattable-NDYUCLVZ.js.map → stattable-LFR3RSD6.js.map} +0 -0
- /package/dist/{studyCatalog-TAXRF5NS.js.map → studyCatalog-RINIZ277.js.map} +0 -0
- /package/dist/{summarizeCnvGeneexp-3QLHU6N7.js.map → summarizeCnvGeneexp-ZQFNPR65.js.map} +0 -0
- /package/dist/{summarizeGeneexpSurvival-ARI4MPFX.js.map → summarizeGeneexpSurvival-GIS7XMMH.js.map} +0 -0
- /package/dist/{summarizeMutationCnv-W7V7CKPI.js.map → summarizeMutationCnv-FWF7YIGR.js.map} +0 -0
- /package/dist/{summary-OUYDWLBF.js.map → summarizeMutationDiagnosis-V5L2OKTK.js.map} +0 -0
- /package/dist/{summarizeMutationSurvival-6TTMSRRX.js.map → summarizeMutationSurvival-LAUUF6XN.js.map} +0 -0
- /package/dist/{termCollection-7P3WU6X6.js.map → summary-OMU3ACNE.js.map} +0 -0
- /package/dist/{summary.integration.spec-4GTCG6HY.js.map → summary.integration.spec-6JZAT73L.js.map} +0 -0
- /package/dist/{summaryInput-UK3TLC7M.js.map → summaryInput-QIKL3HDD.js.map} +0 -0
- /package/dist/{sunburst-2UFHMNH3.js.map → sunburst-32IW2R57.js.map} +0 -0
- /package/dist/{survival-SPWYSDVB.js.map → survival-BMOPVAN2.js.map} +0 -0
- /package/dist/{survival-TL6UZ6FQ.js.map → survival-H5AWMQ36.js.map} +0 -0
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- /package/dist/{termCollectionFractionSelection-YKIE6BME.js.map → termCollection-KNFUELYY.js.map} +0 -0
- /package/dist/{termCollection.unit.spec-EPYC7LOA.js.map → termCollection.unit.spec-S6M6QC4C.js.map} +0 -0
- /package/dist/{tk-X454XH5N.js.map → termCollectionFractionSelection-X22VMJWY.js.map} +0 -0
- /package/dist/{termCollectionFractionSelection.unit.spec-AG2CZPGZ.js.map → termCollectionFractionSelection.unit.spec-ELU6SD7P.js.map} +0 -0
- /package/dist/{tvs.dt-U77PCG6X.js.map → tk-TT666UVE.js.map} +0 -0
- /package/dist/{tk-TOXMU4GT.js.map → tk-UOPNJ323.js.map} +0 -0
- /package/dist/{tp.ui-FDQ76KPL.js.map → tp.ui-HGAHRKO5.js.map} +0 -0
- /package/dist/{vocabulary-64GO4YDB.js.map → tvs.dt-H7YYR4EB.js.map} +0 -0
- /package/dist/{tvs.dtcnv.categorical-XYZU4XLO.js.map → tvs.dtcnv.categorical-IPJTKGMF.js.map} +0 -0
- /package/dist/{tvs.dtcnv.continuous-4GJILFGP.js.map → tvs.dtcnv.continuous-XY5XZ4GH.js.map} +0 -0
- /package/dist/{tvs.dtfusion-7YROAHVI.js.map → tvs.dtfusion-VFCBMXRM.js.map} +0 -0
- /package/dist/{tvs.dtitd-MIYU4ZHH.js.map → tvs.dtitd-RZVW6FTR.js.map} +0 -0
- /package/dist/{tvs.dtsnvindel-XLDY7KWB.js.map → tvs.dtsnvindel-IDPJWSGC.js.map} +0 -0
- /package/dist/{tvs.dtsv-YMLJ37YR.js.map → tvs.dtsv-QERP756F.js.map} +0 -0
- /package/dist/{tvs.samplelst-KIVEXJKD.js.map → tvs.samplelst-6KNDHBIU.js.map} +0 -0
- /package/dist/{tvs.termCollection-4CQV3EB3.js.map → tvs.termCollection-GWPJK3NE.js.map} +0 -0
- /package/dist/{wsi.direct-5MQVRJZX.js.map → wsi.direct-2RBCBXDA.js.map} +0 -0
package/dist/chunk-EKQ7NYOU.js
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import {
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parsesample
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} from "./chunk-52QHIKH2.js";
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import {
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dtfusionrna,
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dtsv,
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mclassfusionrna,
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mclasssv
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} from "./chunk-RUBZCKIX.js";
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// ../shared/utils/dist/src/bulk.sv.js
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function parseheader(line, flag, issv) {
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const header = line.toLowerCase().split(" ");
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if (header.length <= 1) return "invalid file header for fusions";
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const htry = (...lst) => {
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for (const a of lst) {
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const j = header.indexOf(a);
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}
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return -1;
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};
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let i = htry("gene_a", "gene1", "genea");
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if (i == -1) return "gene_a missing from header";
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header[i] = "gene1";
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i = htry("gene_b", "gene2", "geneb");
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if (i == -1) return "gene_b missing from header";
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header[i] = "gene2";
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i = htry("chr_a", "chr1", "chra");
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if (i == -1) return "chr_a missing from header";
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header[i] = "chr1";
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i = htry("chr_b", "chr2", "chrb");
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if (i == -1) return "chr_b missing from header";
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header[i] = "chr2";
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i = htry("pos_a", "position_a", "position1", "posa");
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if (i == -1) return "pos_a missing from header";
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header[i] = "position1";
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i = htry("pos_b", "position_b", "position2", "posb");
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if (i == -1) return "pos_b missing from header";
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header[i] = "position2";
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i = htry("isoform_a", "refseq_a", "refseq1", "isoform1", "sv_refseqa");
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if (i == -1) return "isoform_a missing from header";
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header[i] = "isoform1";
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i = htry("isoform_b", "refseq_b", "refseq2", "isoform2", "sv_refseqb");
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if (i == -1) return "isoform_b missing from header";
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header[i] = "isoform2";
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i = htry("strand_a", "orta");
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if (i == -1) return "strand_a missing from header";
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header[i] = "strand1";
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i = htry("strand_b", "ortb");
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if (i == -1) return "strand_b missing from header";
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header[i] = "strand2";
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i = htry("sample", "sample_name", "tumor_sample_barcode");
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if (i != -1) header[i] = "sample";
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i = htry("patient", "donor", "target_case_id");
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if (i != -1) header[i] = "patient";
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i = htry("sampletype", "sample type", "sample_type");
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if (i != -1) header[i] = "sampletype";
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i = htry("disease");
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if (i != -1) header[i] = "disease";
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i = htry("origin");
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if (i != -1) header[i] = "origin";
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if (issv) {
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flag.sv.loaded = true;
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flag.sv.header = header;
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} else {
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flag.fusion.loaded = true;
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flag.fusion.header = header;
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}
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return false;
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}
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function parseline(i, line, flag, issv) {
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if (line == "" || line[0] == "#") return;
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const lst = line.split(" ");
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const m = {};
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const header = issv ? flag.sv.header : flag.fusion.header;
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const badlines = issv ? flag.sv.badlines : flag.fusion.badlines;
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for (let j = 0; j < header.length; j++) {
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m[header[j]] = lst[j];
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}
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if (!m.chr1) {
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badlines.push([i, "missing chr1", lst]);
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return;
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}
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if (m.chr1.toLowerCase().indexOf("chr") != 0) {
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m.chr1 = "chr" + m.chr1;
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}
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if (!m.chr2) {
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badlines.push([i, "missing chr2", lst]);
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return;
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}
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if (m.chr2.toLowerCase().indexOf("chr") != 0) {
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m.chr2 = "chr" + m.chr2;
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}
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let v = m.position1;
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badlines.push([i, "missing position1", lst]);
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return;
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}
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badlines.push([i, "invalid value for position1", lst]);
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m.position1 = v2;
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badlines.push([i, "missing position2", lst]);
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badlines.push([i, "invalid value for position2", lst]);
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}
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m.position2 = v2;
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return;
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}
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m.isoform1 = void 0;
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}
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}
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const lst2 = m.isoform2.split(",");
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m.isoform2 = void 0;
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for (const t of lst2) {
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}
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}
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if (!m.gene1) {
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m.isoform1 = void 0;
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}
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if (!m.gene2) {
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m.isoform2 = void 0;
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}
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if (m.gene1) {
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flag.good++;
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const m2 = {
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dt: issv ? dtsv : dtfusionrna,
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class: issv ? mclasssv : mclassfusionrna,
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isoform: m.isoform1,
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mname: m.gene2 || m.chr2,
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sample: m.sample,
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patient: m.patient,
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sampletype: m.sampletype,
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origin: m.origin,
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disease: m.disease,
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pairlst: [
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{
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a: {
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name: m.gene1,
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isoform: m.isoform1,
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strand: m.strand1,
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chr: m.chr1,
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position: m.position1
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},
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b: {
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name: m.gene2,
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isoform: m.isoform2,
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strand: m.strand2,
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chr: m.chr2,
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position: m.position2
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}
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}
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]
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};
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const n = flag.geneToUpper ? m.gene1.toUpperCase() : m.gene1;
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if (!flag.data[n]) {
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flag.data[n] = [];
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}
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flag.data[n].push(m2);
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}
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if (m.gene2 && m.gene2 != m.gene1) {
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flag.good++;
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const m2 = {
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dt: issv ? dtsv : dtfusionrna,
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class: issv ? mclasssv : mclassfusionrna,
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isoform: m.isoform2,
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mname: m.gene1 || m.chr1,
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sample: m.sample,
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patient: m.patient,
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sampletype: m.sampletype,
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origin: m.origin,
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disease: m.disease,
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pairlst: [
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{
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a: {
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name: m.gene1,
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isoform: m.isoform1,
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strand: m.strand1,
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chr: m.chr1,
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position: m.position1
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},
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b: {
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name: m.gene2,
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isoform: m.isoform2,
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strand: m.strand2,
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chr: m.chr2,
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position: m.position2
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}
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}
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]
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};
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const n = flag.geneToUpper ? m.gene2.toUpperCase() : m.gene2;
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if (!flag.data[n]) {
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flag.data[n] = [];
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}
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flag.data[n].push(m2);
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}
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}
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function duplicate(m) {
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const n = {};
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for (const k in m) {
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if (k == "pairlst") continue;
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const v = m[k];
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const type = typeof v;
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if (type == "object") {
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parseheader,
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duplicate
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//# sourceMappingURL=chunk-EKQ7NYOU.js.map
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package/dist/chunk-EUQEQOFE.js
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import {
|
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2
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skipPrevActionAbort,
|
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storeInit
|
|
4
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} from "./chunk-LOWJQFCC.js";
|
|
5
|
-
import {
|
|
6
|
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recoverInit
|
|
7
|
-
} from "./chunk-X46YA4CB.js";
|
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|
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import {
|
|
9
|
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AppBase,
|
|
10
|
-
sayerror,
|
|
11
|
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vocabInit
|
|
12
|
-
} from "./chunk-PC4MFDHP.js";
|
|
13
|
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import {
|
|
14
|
-
importPlot
|
|
15
|
-
} from "./chunk-HPAW7XDM.js";
|
|
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|
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import {
|
|
17
|
-
Menu
|
|
18
|
-
} from "./chunk-ELJX3QIQ.js";
|
|
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|
-
import {
|
|
20
|
-
AppApi
|
|
21
|
-
} from "./chunk-WINIL2KN.js";
|
|
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|
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|
|
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|
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// plots/plot.app.ts
|
|
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|
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var PlotApp = class _PlotApp extends AppBase {
|
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constructor(opts, api) {
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|
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|
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this.wasDestroyed = false;
|
|
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|
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|
|
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|
-
this.type = _PlotApp.type;
|
|
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|
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this.dom = this.getDom(opts);
|
|
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|
-
}
|
|
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static {
|
|
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|
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this.type = "app";
|
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|
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}
|
|
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|
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getDom(opts) {
|
|
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const dom = {
|
|
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|
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holder: opts.holder,
|
|
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|
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errdiv: opts.holder.append("div"),
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|
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|
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plotDiv: opts.holder.append("div")
|
|
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|
-
};
|
|
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|
-
const controls = opts.violin?.mode == "minimal" ? null : opts.holder.append("div").style("white-space", "nowrap");
|
|
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|
-
if (controls) {
|
|
44
|
-
dom.plotControls = controls.append("div").style("display", "inline-block");
|
|
45
|
-
dom.recoverControls = controls.append("div").style("display", "inline-block");
|
|
46
|
-
}
|
|
47
|
-
return dom;
|
|
48
|
-
}
|
|
49
|
-
async preApiFreeze(api) {
|
|
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|
-
try {
|
|
51
|
-
api.tip = new Menu({ padding: "5px" });
|
|
52
|
-
api.printError = (e) => this.printError(e);
|
|
53
|
-
const vocab = this.opts.state.vocab;
|
|
54
|
-
api.vocabApi = this.opts.vocabApi ? this.opts.vocabApi : await vocabInit({
|
|
55
|
-
app: api,
|
|
56
|
-
state: {
|
|
57
|
-
vocab: {
|
|
58
|
-
// either (genome + dslabel) XOR (terms) can be undefined
|
|
59
|
-
genome: vocab?.genome || this.opts.state.genome,
|
|
60
|
-
dslabel: vocab?.dslabel || this.opts.state.dslabel,
|
|
61
|
-
terms: vocab?.terms
|
|
62
|
-
}
|
|
63
|
-
},
|
|
64
|
-
fetchOpts: this.opts.fetchOpts
|
|
65
|
-
});
|
|
66
|
-
this.opts.state.vocab = api.vocabApi.vocab;
|
|
67
|
-
} catch (e) {
|
|
68
|
-
console.log(`preApiFreeze error`, e);
|
|
69
|
-
throw e;
|
|
70
|
-
}
|
|
71
|
-
}
|
|
72
|
-
async init() {
|
|
73
|
-
try {
|
|
74
|
-
this.opts.state.nav = { header_mode: "hidden" };
|
|
75
|
-
this.store = await storeInit({ app: this.api, state: this.opts.state });
|
|
76
|
-
this.state = await this.store.copyState();
|
|
77
|
-
this.components = {
|
|
78
|
-
plots: {}
|
|
79
|
-
};
|
|
80
|
-
if (this.opts.app?.features?.includes("recover"))
|
|
81
|
-
this.components.recover = await recoverInit({
|
|
82
|
-
app: this.api,
|
|
83
|
-
holder: this.dom.recoverControls,
|
|
84
|
-
// TODO: ???? may limit the tracked state to only the filter, activeCohort ???
|
|
85
|
-
getState: (appState) => appState,
|
|
86
|
-
//reactsTo: action => true, //action.type != 'plot_edit' || action.type == 'app_refresh',
|
|
87
|
-
maxHistoryLen: 10
|
|
88
|
-
});
|
|
89
|
-
if (this.opts.app?.doNotAwaitInitRender) {
|
|
90
|
-
this.api.dispatch();
|
|
91
|
-
} else {
|
|
92
|
-
await this.api.dispatch();
|
|
93
|
-
}
|
|
94
|
-
} catch (e) {
|
|
95
|
-
this.printError(e);
|
|
96
|
-
throw e;
|
|
97
|
-
}
|
|
98
|
-
}
|
|
99
|
-
async main() {
|
|
100
|
-
this.api.vocabApi.main();
|
|
101
|
-
for (const id in this.components.plots) {
|
|
102
|
-
const plot = this.components.plots[id];
|
|
103
|
-
if (!this.state.plots.find((p) => p.id === plot.id)) {
|
|
104
|
-
plot.destroy();
|
|
105
|
-
delete this.components.plots[id];
|
|
106
|
-
}
|
|
107
|
-
}
|
|
108
|
-
for (const plot of this.state.plots.values()) {
|
|
109
|
-
if (plot.parentId) continue;
|
|
110
|
-
if (!this.components.plots[plot.id]) {
|
|
111
|
-
const holder = this.opts?.app?.getPlotHolder ? this.opts.app.getPlotHolder(plot, this.dom.holder) : this.dom.holder.append("div");
|
|
112
|
-
if (!this.dom.plotDiv) this.dom.plotDiv = holder;
|
|
113
|
-
const { componentInit } = await importPlot(plot.chartType);
|
|
114
|
-
const plotApi = await componentInit({
|
|
115
|
-
id: plot.id,
|
|
116
|
-
app: this.api,
|
|
117
|
-
holder,
|
|
118
|
-
controls: this.dom.plotControls
|
|
119
|
-
});
|
|
120
|
-
this.components.plots[plot.id] = plotApi;
|
|
121
|
-
}
|
|
122
|
-
}
|
|
123
|
-
}
|
|
124
|
-
printError(e) {
|
|
125
|
-
sayerror(this.dom.errdiv, "Error: " + (e.message || e));
|
|
126
|
-
if (e.stack) console.log(e.stack);
|
|
127
|
-
this.bus.emit("error");
|
|
128
|
-
}
|
|
129
|
-
skipPrevActionAbort(action) {
|
|
130
|
-
return skipPrevActionAbort(action);
|
|
131
|
-
}
|
|
132
|
-
destroy() {
|
|
133
|
-
if (this.dom?.holder) this.dom.holder.selectAll("*").remove();
|
|
134
|
-
}
|
|
135
|
-
};
|
|
136
|
-
var appInit = AppApi.getInitFxn(PlotApp);
|
|
137
|
-
|
|
138
|
-
export {
|
|
139
|
-
appInit
|
|
140
|
-
};
|
|
141
|
-
//# sourceMappingURL=chunk-EUQEQOFE.js.map
|
package/dist/chunk-FKA55PHV.js
DELETED
|
@@ -1,281 +0,0 @@
|
|
|
1
|
-
import {
|
|
2
|
-
getMclassSorter,
|
|
3
|
-
getSampleGroupSorter,
|
|
4
|
-
getSampleSorter,
|
|
5
|
-
getTermSorter
|
|
6
|
-
} from "./chunk-4KJSNR5E.js";
|
|
7
|
-
import {
|
|
8
|
-
setRelatedSamples
|
|
9
|
-
} from "./chunk-C2MCQZWH.js";
|
|
10
|
-
import {
|
|
11
|
-
filterVariantValues,
|
|
12
|
-
sample_match_termvaluesetting
|
|
13
|
-
} from "./chunk-A2ORIMUJ.js";
|
|
14
|
-
import {
|
|
15
|
-
dtcnv,
|
|
16
|
-
dtfusionrna,
|
|
17
|
-
dtgeneexpression,
|
|
18
|
-
dtsnvindel
|
|
19
|
-
} from "./chunk-RUBZCKIX.js";
|
|
20
|
-
import {
|
|
21
|
-
__export
|
|
22
|
-
} from "./chunk-HS5PO5ZQ.js";
|
|
23
|
-
|
|
24
|
-
// plots/matrix/matrix.groups.js
|
|
25
|
-
var matrix_groups_exports = {};
|
|
26
|
-
__export(matrix_groups_exports, {
|
|
27
|
-
classifyValues: () => classifyValues,
|
|
28
|
-
getSampleGroups: () => getSampleGroups,
|
|
29
|
-
getSampleOrder: () => getSampleOrder,
|
|
30
|
-
getTermOrder: () => getTermOrder,
|
|
31
|
-
stackSiblingCellsByClass: () => stackSiblingCellsByClass
|
|
32
|
-
});
|
|
33
|
-
function getTermOrder(data) {
|
|
34
|
-
const s = this.settings.matrix;
|
|
35
|
-
this.termSorter = getTermSorter(this, s);
|
|
36
|
-
const termOrder = [];
|
|
37
|
-
let totalIndex = 0, visibleGrpIndex = 0, numClusterTerms = 0;
|
|
38
|
-
this.mclassSorter = getMclassSorter(this);
|
|
39
|
-
this.samplesByAncestorId = /* @__PURE__ */ new Map();
|
|
40
|
-
const seenAncestorSamples = /* @__PURE__ */ new Set();
|
|
41
|
-
for (const sd of data.lst) {
|
|
42
|
-
if (seenAncestorSamples.has(sd.sample)) continue;
|
|
43
|
-
seenAncestorSamples.add(sd.sample);
|
|
44
|
-
if (!sd._ref_?.ancestors) continue;
|
|
45
|
-
for (const a of sd._ref_.ancestors) {
|
|
46
|
-
const id = a.ancestor_id;
|
|
47
|
-
if (id === void 0) continue;
|
|
48
|
-
if (!this.samplesByAncestorId.has(id)) this.samplesByAncestorId.set(id, /* @__PURE__ */ new Set());
|
|
49
|
-
this.samplesByAncestorId.get(id).add(sd);
|
|
50
|
-
}
|
|
51
|
-
}
|
|
52
|
-
for (const [grpIndex, grp] of this.termGroups.entries()) {
|
|
53
|
-
const lst = [];
|
|
54
|
-
for (const [index, tw] of grp.lst.entries()) {
|
|
55
|
-
const counts = { samples: 0, hits: 0 };
|
|
56
|
-
const countedSamples = /* @__PURE__ */ new Set();
|
|
57
|
-
for (const sd of data.lst) {
|
|
58
|
-
if (countedSamples.has(sd.sample)) continue;
|
|
59
|
-
countedSamples.add(sd.sample);
|
|
60
|
-
const anno = sd[tw.$id];
|
|
61
|
-
if (anno) {
|
|
62
|
-
const { filteredValues, countedValues, renderedValues } = this.classifyValues(anno, tw, grp, s, sd);
|
|
63
|
-
anno.filteredValues = filteredValues;
|
|
64
|
-
anno.countedValues = countedValues;
|
|
65
|
-
anno.renderedValues = renderedValues;
|
|
66
|
-
if (anno.countedValues?.length) {
|
|
67
|
-
const v = tw.term.values?.[anno.value];
|
|
68
|
-
if (v?.uncountable) continue;
|
|
69
|
-
counts.samples += 1;
|
|
70
|
-
counts.hits += anno.countedValues.length;
|
|
71
|
-
if (tw.q?.mode == "continuous") {
|
|
72
|
-
const v2 = anno.value;
|
|
73
|
-
if (!("minval" in counts) || counts.minval > v2) counts.minval = v2;
|
|
74
|
-
if (!("maxval" in counts) || counts.maxval < v2) counts.maxval = v2;
|
|
75
|
-
}
|
|
76
|
-
}
|
|
77
|
-
}
|
|
78
|
-
}
|
|
79
|
-
if (grp.type != "hierCluster" || counts.samples) lst.push({ tw, counts, index });
|
|
80
|
-
if (grp.type == "hierCluster") numClusterTerms++;
|
|
81
|
-
}
|
|
82
|
-
const termSorter = grp.sortTermsBy || grp.type == "hierCluster" ? getTermSorter(this, s, grp) : this.termSorter;
|
|
83
|
-
const processedLst = lst.filter((t) => {
|
|
84
|
-
if ("minNumSamples" in t.tw) return t.tw.minNumSamples <= t.counts.samples;
|
|
85
|
-
if (!grp.settings) return true;
|
|
86
|
-
return !("minNumSamples" in grp.settings) || t.counts.samples >= grp.settings.minNumSamples;
|
|
87
|
-
}).sort(termSorter);
|
|
88
|
-
if (!processedLst.length) continue;
|
|
89
|
-
for (const [index, t] of processedLst.entries()) {
|
|
90
|
-
const { tw, counts } = t;
|
|
91
|
-
const ref = data.refs.byTermId[t.tw.$id] || {};
|
|
92
|
-
termOrder.push({
|
|
93
|
-
grp,
|
|
94
|
-
grpIndex,
|
|
95
|
-
visibleGrpIndex,
|
|
96
|
-
tw,
|
|
97
|
-
index,
|
|
98
|
-
// rendered index
|
|
99
|
-
lstIndex: t.index,
|
|
100
|
-
// as-listed index, before applying term filters
|
|
101
|
-
processedLst,
|
|
102
|
-
prevGrpTotalIndex: totalIndex,
|
|
103
|
-
totalIndex: totalIndex + index,
|
|
104
|
-
ref,
|
|
105
|
-
allCounts: counts
|
|
106
|
-
// note: term label will be assigned after sample counts are known
|
|
107
|
-
// label: t.tw.label || t.tw.term.name,
|
|
108
|
-
});
|
|
109
|
-
}
|
|
110
|
-
totalIndex += processedLst.length;
|
|
111
|
-
visibleGrpIndex += 1;
|
|
112
|
-
}
|
|
113
|
-
for (const [ancestor_id, samples] of this.samplesByAncestorId.entries()) {
|
|
114
|
-
if (samples.size < 2) this.samplesByAncestorId.delete(ancestor_id);
|
|
115
|
-
}
|
|
116
|
-
this.numTerms = termOrder.length;
|
|
117
|
-
this.numClusterTerms = numClusterTerms;
|
|
118
|
-
return termOrder;
|
|
119
|
-
}
|
|
120
|
-
function getSampleGroups(data) {
|
|
121
|
-
const s = this.settings.matrix;
|
|
122
|
-
const defaultSampleGrp = {
|
|
123
|
-
id: this.config.divideBy?.$id,
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124
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name: this.config.divideBy ? "Not annotated" : "",
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125
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lst: []
|
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126
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};
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127
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const sampleGroups = /* @__PURE__ */ new Map();
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128
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const term = this.config.divideBy?.term || {};
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129
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const $id = this.config.divideBy?.$id || "-";
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130
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const exclude = this.config.divideBy?.exclude || [];
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131
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const values = term.values || {};
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132
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const ref = data.refs.byTermId[$id] || {};
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133
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for (const row of data.lst) {
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134
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if ($id in row) {
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135
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const cell = row[$id];
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136
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const keys = term.type == "multivalue" && Array.isArray(cell.values) ? cell.values.map((v) => v.key) : [cell.key];
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137
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for (const key of keys) {
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138
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const name = key in values && values[key].label ? values[key].label : key;
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139
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if (!sampleGroups.has(key)) {
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140
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const grp = {
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141
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name: `${name}`,
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142
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// convert to a string
|
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143
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id: key,
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144
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lst: [],
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145
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tw: this.config.divideBy,
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146
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legendGroups: {},
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147
|
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isExcluded: exclude.includes(key)
|
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148
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};
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149
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if (ref.bins && s.sortSampleGrpsBy == "name") grp.order = ref.bins.findIndex((bin) => bin.name == key);
|
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150
|
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else delete grp.order;
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151
|
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sampleGroups.set(key, grp);
|
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152
|
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}
|
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153
|
-
sampleGroups.get(key).lst.push(row);
|
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154
|
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}
|
|
155
|
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} else {
|
|
156
|
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defaultSampleGrp.lst.push(row);
|
|
157
|
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}
|
|
158
|
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}
|
|
159
|
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const sampleGrpsArr = [...sampleGroups.values()];
|
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160
|
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const n = sampleGroups.size;
|
|
161
|
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if (n > 100 && sampleGrpsArr.filter((sg) => sg.lst.length < 3).length > 0.8 * n) {
|
|
162
|
-
const l = s.controlLabels;
|
|
163
|
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throw `Did not group ${l.samples} by "${term.name}": too many ${l.sample} groups (${n}), with the majority of groups having <= 2 ${l.samples} per group.`;
|
|
164
|
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}
|
|
165
|
-
if (defaultSampleGrp.lst.length && !sampleGroups.size) {
|
|
166
|
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sampleGroups.set(void 0, defaultSampleGrp);
|
|
167
|
-
sampleGrpsArr.push(...sampleGroups.values());
|
|
168
|
-
}
|
|
169
|
-
this.asListedSampleOrder = [];
|
|
170
|
-
for (const grp of sampleGrpsArr) {
|
|
171
|
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this.asListedSampleOrder.push(...grp.lst.map((s2) => s2.sample));
|
|
172
|
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}
|
|
173
|
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const selectedDictTerms = this.termOrder.filter((t) => t.tw.sortSamples && t.tw.term.type != "geneVariant");
|
|
174
|
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const noGrpSampleSorter = getSampleSorter(this, s, data.lst, {
|
|
175
|
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skipSorter: (p, tw) => !p.types?.includes("geneVariant") && selectedDictTerms.find((t) => t.tw.$id === tw.$id)
|
|
176
|
-
});
|
|
177
|
-
const noGrpSampleOrder = data.lst.sort(noGrpSampleSorter);
|
|
178
|
-
const allowedSamples = noGrpSampleOrder.slice(0, s.maxSample);
|
|
179
|
-
const dataFilter = (d) => allowedSamples.includes(d);
|
|
180
|
-
const hitsPerSample = (t, c) => t + (typeof c == "object" && c.countedValues?.length ? 1 : 0);
|
|
181
|
-
const countHits = (total, d) => total + (Object.values(d).reduce(hitsPerSample, 0) ? 1 : 0);
|
|
182
|
-
const grpLstSampleSorter = getSampleSorter(this, s, data.lst);
|
|
183
|
-
for (const grp of sampleGrpsArr) {
|
|
184
|
-
grp.lst = grp.lst.filter(dataFilter);
|
|
185
|
-
grp.totalCountedValues = grp.lst.reduce(countHits, 0);
|
|
186
|
-
grp.lst.sort(grpLstSampleSorter);
|
|
187
|
-
if (this.config.chartType == "matrix" && s.sortBySampleAncestry) setRelatedSamples(grp);
|
|
188
|
-
}
|
|
189
|
-
const sampleGrpSorter = getSampleGroupSorter(this);
|
|
190
|
-
return sampleGrpsArr.sort(sampleGrpSorter);
|
|
191
|
-
}
|
|
192
|
-
function getSampleOrder(data) {
|
|
193
|
-
const s = this.settings.matrix;
|
|
194
|
-
this.visibleSampleGrps = /* @__PURE__ */ new Set();
|
|
195
|
-
const sampleOrder = [];
|
|
196
|
-
let total = 0, numHiddenGrps = 0;
|
|
197
|
-
for (const [grpIndex, grp] of this.sampleGroups.entries()) {
|
|
198
|
-
if (!grp.lst.length) continue;
|
|
199
|
-
if (grp.isExcluded) numHiddenGrps++;
|
|
200
|
-
let processedLst = grp.lst;
|
|
201
|
-
for (const [index, row] of processedLst.entries()) {
|
|
202
|
-
sampleOrder.push({
|
|
203
|
-
grp,
|
|
204
|
-
grpIndex: grpIndex - numHiddenGrps,
|
|
205
|
-
// : this.sampleGroups.length,
|
|
206
|
-
row,
|
|
207
|
-
index,
|
|
208
|
-
prevGrpTotalIndex: total,
|
|
209
|
-
totalIndex: total + index,
|
|
210
|
-
totalHtAdjustments: 0,
|
|
211
|
-
// may be required when transposed???
|
|
212
|
-
grpTotals: { htAdjustment: 0 },
|
|
213
|
-
// may be required when transposed???
|
|
214
|
-
processedLst
|
|
215
|
-
});
|
|
216
|
-
}
|
|
217
|
-
if (!grp.isExcluded) total += processedLst.length;
|
|
218
|
-
this.visibleSampleGrps.add(grp);
|
|
219
|
-
}
|
|
220
|
-
this.unfilteredSampleOrder = sampleOrder;
|
|
221
|
-
return sampleOrder.filter((so) => !so.grp.isExcluded);
|
|
222
|
-
}
|
|
223
|
-
function classifyValues(anno, tw, grp, s, sample) {
|
|
224
|
-
let values = "value" in anno ? [anno.value] : anno.values;
|
|
225
|
-
if (!values) return { filteredValues: null, countedValues: null, renderedValues: null };
|
|
226
|
-
if (tw.term.type == "geneVariant" && tw.q?.type == "values" && tw.q.variantFilter) {
|
|
227
|
-
values = filterVariantValues(values, tw.q.variantFilter);
|
|
228
|
-
}
|
|
229
|
-
const isSpecific = [tw.valueFilter || grp.valueFilter].filter((v) => v && true);
|
|
230
|
-
if (isSpecific.length && isSpecific[0].type !== "tvs" && isSpecific[0].type !== "tvslst")
|
|
231
|
-
throw `unknown matrix value filter type='${isSpecific.type}'`;
|
|
232
|
-
let filteredValues = !isSpecific.length ? values : values.filter((v) => sample_match_termvaluesetting(v, isSpecific[0], tw.term, sample));
|
|
233
|
-
const renderedValues = [];
|
|
234
|
-
if (tw.term.type == "geneVariant" && tw.q?.type == "values") {
|
|
235
|
-
filteredValues.sort(this.mclassSorter);
|
|
236
|
-
if (s.cellEncoding == "") renderedValues.push(...filteredValues);
|
|
237
|
-
else {
|
|
238
|
-
const sortedFilteredValues = [];
|
|
239
|
-
for (const dt of [dtcnv, dtsnvindel, dtfusionrna, dtgeneexpression]) {
|
|
240
|
-
const v = dt == dtgeneexpression ? filteredValues.find((v2) => v2.dt === dt) : filteredValues.find((v2) => v2.dt === dt && v2.class !== "WT" && v2.class !== "Blank");
|
|
241
|
-
if (v) renderedValues.push(v);
|
|
242
|
-
const oneDtV = filteredValues.filter((v2) => v2.dt === dt);
|
|
243
|
-
sortedFilteredValues.push(...oneDtV);
|
|
244
|
-
}
|
|
245
|
-
filteredValues = sortedFilteredValues;
|
|
246
|
-
}
|
|
247
|
-
} else {
|
|
248
|
-
renderedValues.push(...filteredValues);
|
|
249
|
-
}
|
|
250
|
-
return {
|
|
251
|
-
filteredValues,
|
|
252
|
-
countedValues: filteredValues.filter((v) => {
|
|
253
|
-
if (tw.term.type == "geneVariant") {
|
|
254
|
-
if (tw.q?.type == "predefined-groupset" || tw.q?.type == "custom-groupset") {
|
|
255
|
-
const groupset = tw.q.type == "predefined-groupset" ? tw.term.groupsetting.lst[tw.q.predefined_groupset_idx] : tw.q.customset;
|
|
256
|
-
if (!groupset) throw "groupset not found";
|
|
257
|
-
const group = groupset.groups[0];
|
|
258
|
-
if (v != group.name) return false;
|
|
259
|
-
} else {
|
|
260
|
-
if (v.class == "WT" || v.class == "Blank" || s.geneVariantCountSamplesSkipMclass.includes(v.class))
|
|
261
|
-
return false;
|
|
262
|
-
}
|
|
263
|
-
}
|
|
264
|
-
return true;
|
|
265
|
-
}),
|
|
266
|
-
renderedValues
|
|
267
|
-
};
|
|
268
|
-
}
|
|
269
|
-
function stackSiblingCellsByClass(a, b) {
|
|
270
|
-
return a.class === b.class ? 0 : a.class === "Blank" ? 1 : b.class == "Blank" ? -1 : a.class < b.class ? -1 : 1;
|
|
271
|
-
}
|
|
272
|
-
|
|
273
|
-
export {
|
|
274
|
-
getTermOrder,
|
|
275
|
-
getSampleGroups,
|
|
276
|
-
getSampleOrder,
|
|
277
|
-
classifyValues,
|
|
278
|
-
stackSiblingCellsByClass,
|
|
279
|
-
matrix_groups_exports
|
|
280
|
-
};
|
|
281
|
-
//# sourceMappingURL=chunk-FKA55PHV.js.map
|