@sjcrh/proteinpaint-client 2.191.3 → 2.191.4

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (888) hide show
  1. package/dist/2dmaf-Z3D2M3FB.js +1373 -0
  2. package/dist/AIProjectAdmin-2OQOQXH4.js +956 -0
  3. package/dist/AppHeader-PXLGVCVS.js +835 -0
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  5. package/dist/CorrelationVolcano-RO6CFLZA.js +619 -0
  6. package/dist/DE-CCA5SBJG.js +95 -0
  7. package/dist/DEinput-MRUQW6X6.js +301 -0
  8. package/dist/DifferentialAnalysis-5YQQLJKR.js +245 -0
  9. package/dist/Disco-4FTOJBLG.js +3237 -0
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  159. package/dist/dnaMethylation-WGJMJL5B.js +38 -0
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  813. /package/dist/{plot.disco-BLNU4I6Q.js.map → plot.disco-OUE4RFHL.js.map} +0 -0
  814. /package/dist/{plot.dzi-FKWY6K5Q.js.map → plot.dzi-T3GPUH36.js.map} +0 -0
  815. /package/dist/{plot.ssgq-3GTTOOMK.js.map → plot.ssgq-WJHGMXW5.js.map} +0 -0
  816. /package/dist/{plot.vaf2cov-UAI64HYN.js.map → plot.vaf2cov-NGD5PCV4.js.map} +0 -0
  817. /package/dist/{plot.wsi-QJ52IJXL.js.map → plot.wsi-2MU5BDG3.js.map} +0 -0
  818. /package/dist/{polar2-6S4IHKK4.js.map → polar2-YCWPBPFU.js.map} +0 -0
  819. /package/dist/{profileForms-WXWHZ56N.js.map → profileForms-OV3I6RK7.js.map} +0 -0
  820. /package/dist/{profilePlot-K7ICCFQ3.js.map → profilePlot-OMVO3K4H.js.map} +0 -0
  821. /package/dist/{proteinView-ALZTEKTC.js.map → proteinView-OAR2RC6U.js.map} +0 -0
  822. /package/dist/{qualitative-QMPO7EY6.js.map → qualitative-MEYBRUC6.js.map} +0 -0
  823. /package/dist/{radar2-LDAFJHSI.js.map → radar2-KREAMGVV.js.map} +0 -0
  824. /package/dist/{radarFacility2-3TX3U243.js.map → radarFacility2-DBPEV7VC.js.map} +0 -0
  825. /package/dist/{regression-DUUCJOFW.js.map → regression-ZPDPLI6G.js.map} +0 -0
  826. /package/dist/{regression.inputs-B6SFFVED.js.map → regression.inputs-QOSBAGL6.js.map} +0 -0
  827. /package/dist/{regression.inputs.term-P5NHX7ME.js.map → regression.inputs.term-HMUMPY7X.js.map} +0 -0
  828. /package/dist/{regression.inputs.values.table-MVPP5VAK.js.map → regression.inputs.values.table-VMCTZHLG.js.map} +0 -0
  829. /package/dist/{regression.integration.spec-T7VH46WO.js.map → regression.integration.spec-RP74JTAA.js.map} +0 -0
  830. /package/dist/{regression.results-QEP4T6JO.js.map → regression.results-5XC6M67C.js.map} +0 -0
  831. /package/dist/{regression.spec-BTBCBKMF.js.map → regression.spec-EZYM24J7.js.map} +0 -0
  832. /package/dist/{report-WYCH4DJX.js.map → report-ZOVQCOGQ.js.map} +0 -0
  833. /package/dist/{sampleScatter.spec-LC6K22FF.js.map → sampleScatter.spec-CD52FEOC.js.map} +0 -0
  834. /package/dist/{sampleView-V3JYDTRA.js.map → sampleView-SVTLSWRG.js.map} +0 -0
  835. /package/dist/{samplelst-JO7UROYA.js.map → samplelst-HXF5POJD.js.map} +0 -0
  836. /package/dist/{samplematrix-6526IJRO.js.map → samplematrix-NYDAH74I.js.map} +0 -0
  837. /package/dist/{sc-EUC7G5OV.js.map → sc-JIDT4W4K.js.map} +0 -0
  838. /package/dist/{scatter-UMK37C4M.js.map → scatter-WNRTPSEE.js.map} +0 -0
  839. /package/dist/{scatter.integration.spec-BTOB6Y4H.js.map → scatter.integration.spec-3EYTPY5B.js.map} +0 -0
  840. /package/dist/{selectGenomeWithTklst-JNEOHP4V.js.map → selectGenomeWithTklst-OSB7B6L3.js.map} +0 -0
  841. /package/dist/{singleCellCellType-ZDMKPQ2Q.js.map → singleCellCellType-3BH7LWQ6.js.map} +0 -0
  842. /package/dist/{singleCellCellType.unit.spec-BKGRNHYP.js.map → singleCellCellType.unit.spec-RU4RJXFF.js.map} +0 -0
  843. /package/dist/{singleCellGeneExpression-J5KFX7TD.js.map → singleCellGeneExpression-3UA4YER7.js.map} +0 -0
  844. /package/dist/{singleCellGeneExpression.unit.spec-6F5YFV7K.js.map → singleCellGeneExpression.unit.spec-4ZTBG37H.js.map} +0 -0
  845. /package/dist/{singleCellPlot-VA6SWR5L.js.map → singleCellPlot-ZUAWK5RE.js.map} +0 -0
  846. /package/dist/{singlecell-A4OHBVJD.js.map → singlecell-BGJZB7MF.js.map} +0 -0
  847. /package/dist/{singlecell-2CWHJR2P.js.map → singlecell-RO3BL5OO.js.map} +0 -0
  848. /package/dist/{snp-PJNNPOSF.js.map → snp-HD7VQKBR.js.map} +0 -0
  849. /package/dist/{snp.unit.spec-JKZCYPNA.js.map → snp.unit.spec-ISXCLMWW.js.map} +0 -0
  850. /package/dist/{snplocus-YY6UIS2R.js.map → snplocus-IL5Z4XWV.js.map} +0 -0
  851. /package/dist/{spliceevent.a53ss.diagram-CEFGK2LA.js.map → spliceevent.a53ss.diagram-LLJSPV7M.js.map} +0 -0
  852. /package/dist/{spliceevent.exonskip.diagram-A24TZTQ7.js.map → spliceevent.exonskip.diagram-LAOIOIST.js.map} +0 -0
  853. /package/dist/{spliceevent.noeventdiagram-USD42ZZB.js.map → spliceevent.noeventdiagram-MVA7Q3HT.js.map} +0 -0
  854. /package/dist/{ssGSEA-A5X56E7U.js.map → ssGSEA-7T6S3DSE.js.map} +0 -0
  855. /package/dist/{ssGSEA.unit.spec-6WMGKWNI.js.map → ssGSEA.unit.spec-XJ3W4NWX.js.map} +0 -0
  856. /package/dist/{summarizeCnvGeneexp-FZJL4Q7O.js.map → summarizeCnvGeneexp-RRP6JUV6.js.map} +0 -0
  857. /package/dist/{summarizeGeneexpSurvival-LRJZBHRW.js.map → summarizeGeneexpSurvival-AFLHDD6Q.js.map} +0 -0
  858. /package/dist/{summarizeMutationCnv-L64CVMHI.js.map → summarizeMutationCnv-NABUYHMX.js.map} +0 -0
  859. /package/dist/{summarizeMutationDiagnosis-S55CKGBO.js.map → summarizeMutationDiagnosis-2LQ7JU3K.js.map} +0 -0
  860. /package/dist/{summarizeMutationSurvival-AM7BZVDP.js.map → summarizeMutationSurvival-3WBT5TXG.js.map} +0 -0
  861. /package/dist/{summary-ANZTET2T.js.map → summary-FRDKOFXW.js.map} +0 -0
  862. /package/dist/{summary.integration.spec-TW3CJTDA.js.map → summary.integration.spec-ZLRIA7G2.js.map} +0 -0
  863. /package/dist/{summaryInput-3JHKZU62.js.map → summaryInput-4JO6MHP4.js.map} +0 -0
  864. /package/dist/{sunburst-ABDTE22P.js.map → sunburst-DRCVSC2X.js.map} +0 -0
  865. /package/dist/{survival-HROP7OR7.js.map → survival-AK75COPY.js.map} +0 -0
  866. /package/dist/{survival-KZDESA36.js.map → survival-IF5NI3A6.js.map} +0 -0
  867. /package/dist/{survival.integration.spec-CMZTALBF.js.map → survival.integration.spec-7IWBTPJG.js.map} +0 -0
  868. /package/dist/{svgraph-TLRXKVWQ.js.map → svgraph-QBDF2SLB.js.map} +0 -0
  869. /package/dist/{svmr-R4QOXWQW.js.map → svmr-O4GJJUT2.js.map} +0 -0
  870. /package/dist/{table-QM3RZQ5R.js.map → table-FQAIXKLE.js.map} +0 -0
  871. /package/dist/{termCollection-WVYJHPIH.js.map → termCollection-GMDDL3L7.js.map} +0 -0
  872. /package/dist/{termCollection-B2A3MSCD.js.map → termCollection-ZO5PZ7E3.js.map} +0 -0
  873. /package/dist/{termCollection.unit.spec-TCPEEZHW.js.map → termCollection.unit.spec-5JBCTXHX.js.map} +0 -0
  874. /package/dist/{tk-DGFFDV7C.js.map → tk-GJX23IV7.js.map} +0 -0
  875. /package/dist/{tp.ui-BEESUHHF.js.map → tp.ui-T7FVMTGQ.js.map} +0 -0
  876. /package/dist/{tvs.dt-UZW3L4MO.js.map → tvs.dt-X7L7NSU6.js.map} +0 -0
  877. /package/dist/{tvs.dtcnv.categorical-OH5NXCDN.js.map → tvs.dtcnv.categorical-73G2V6CH.js.map} +0 -0
  878. /package/dist/{tvs.dtcnv.continuous-VWWTWAX2.js.map → tvs.dtcnv.continuous-DWFJL3X7.js.map} +0 -0
  879. /package/dist/{tvs.dtfusion-YKYYCDJN.js.map → tvs.dtfusion-HQADHCSV.js.map} +0 -0
  880. /package/dist/{tvs.dtsnvindel-Y3WAHLKK.js.map → tvs.dtsnvindel-PY5OBMGW.js.map} +0 -0
  881. /package/dist/{tvs.dtsv-UFLR2XRY.js.map → tvs.dtsv-OTBEEWSW.js.map} +0 -0
  882. /package/dist/{tvs.samplelst-BPWZHD62.js.map → tvs.samplelst-LCXSU5MG.js.map} +0 -0
  883. /package/dist/{tvs.termCollection-JLA3JQFX.js.map → tvs.termCollection-L527XN4X.js.map} +0 -0
  884. /package/dist/{violin-TFNQIETS.js.map → violin-6VKRUQV3.js.map} +0 -0
  885. /package/dist/{violin.integration.spec-XKNZQVN7.js.map → violin.integration.spec-RJATDLQH.js.map} +0 -0
  886. /package/dist/{violin.interactivity-R2EYNWI6.js.map → violin.interactivity-SKF5H7MN.js.map} +0 -0
  887. /package/dist/{violin.renderer-5WA4YLGB.js.map → violin.renderer-GB4TPX3B.js.map} +0 -0
  888. /package/dist/{vocabulary-D2XUEKI6.js.map → vocabulary-D3W44IWE.js.map} +0 -0
@@ -0,0 +1,477 @@
1
+ import {
2
+ rehydrateFilter
3
+ } from "./chunk-SKMFMGCD.js";
4
+ import {
5
+ findParent,
6
+ getFilter,
7
+ getFilterItemByTag,
8
+ getSamplelstTW
9
+ } from "./chunk-SA7APTJR.js";
10
+ import {
11
+ importPlot
12
+ } from "./chunk-SKREEF3H.js";
13
+ import {
14
+ StoreApi,
15
+ StoreBase
16
+ } from "./chunk-M3J4MINX.js";
17
+ import {
18
+ CustomError
19
+ } from "./chunk-JNITUVXP.js";
20
+
21
+ // mass/store.ts
22
+ var idPrefix = "_MASS_AUTOID_" + Math.random().toString().slice(-6);
23
+ var id = 0;
24
+ var usedPlotIds = /* @__PURE__ */ new Set();
25
+ function getId() {
26
+ return idPrefix + "_" + id++;
27
+ }
28
+ var navHeaderModes = /* @__PURE__ */ new Set([
29
+ "with_tabs",
30
+ // default, shows tabs cohort/charts/filter etc
31
+ "hidden",
32
+ // no header
33
+ "search_only",
34
+ // ?
35
+ "hide_search",
36
+ // ?
37
+ "with_cohortHtmlSelect",
38
+ // only show cohort toggle as <select>
39
+ "only_buttons"
40
+ ]);
41
+ var defaultState = {
42
+ nav: {
43
+ header_mode: "with_tabs",
44
+ activeTab: 0
45
+ // -1 for no active tab and all closed
46
+ },
47
+ // will be ignored if there is no dataset termdb.selectCohort
48
+ // or value will be set to match a filter node that has been tagged
49
+ // as 'cohortfilter' in state.termfilter.filter
50
+ activeCohort: 0,
51
+ search: { isVisible: true },
52
+ plots: [],
53
+ termfilter: {
54
+ filter: {
55
+ type: "tvslst",
56
+ in: true,
57
+ join: "",
58
+ lst: []
59
+ }
60
+ },
61
+ reuse: {
62
+ customTermQ: {
63
+ byId: {},
64
+ // non-dictionary terms do not have a term.id,
65
+ // save by term.type + name?
66
+ byName: {}
67
+ }
68
+ },
69
+ groups: [],
70
+ // element: {name=str, filter={}}, to show in Groups tab
71
+ customTerms: [],
72
+ // element: {name=str, term={}}, able to attach more attr to object if needed
73
+ autoSave: true
74
+ };
75
+ var MassStore = class extends StoreBase {
76
+ constructor(opts, api) {
77
+ super(opts);
78
+ // expected class-specific props
79
+ this.defaultState = defaultState;
80
+ this.plotAdjusters = /* @__PURE__ */ new WeakMap();
81
+ this.app = opts.app;
82
+ this.api = api;
83
+ this.type = "store";
84
+ let savedState = {};
85
+ try {
86
+ const key = window.navigator.webdriver && window["SJPP_E2E_STORAGE_STATES_KEY"];
87
+ const savedStateStr = key && window.localStorage.getItem("SJPP_E2E_STORAGE_STATES") || "{}";
88
+ savedState = JSON.parse(savedStateStr)[key]?.state || {};
89
+ } catch (_) {
90
+ savedState = {};
91
+ }
92
+ this.state = this.copyMerge(this.toJson(defaultState), opts.state, savedState);
93
+ this.prevGeneratedId = 0;
94
+ }
95
+ static {
96
+ this.type = "store";
97
+ }
98
+ validateOpts(opts) {
99
+ const s = opts.state;
100
+ if (s.vocab.dslabel) {
101
+ if (!s.vocab.genome) throw ".state[.vocab].genome missing";
102
+ } else {
103
+ if (!Array.isArray(s.vocab.terms)) throw "vocab.terms must be an array of objects";
104
+ }
105
+ return opts;
106
+ }
107
+ validateState() {
108
+ if (!navHeaderModes.has(this.state.nav.header_mode)) throw "invalid state.nav.header_mode";
109
+ }
110
+ async init() {
111
+ try {
112
+ this.state.termdbConfig = await this.app.vocabApi.getTermdbConfig();
113
+ await this.setTermfilter();
114
+ await this.rehydrateGroups();
115
+ await this.app.vocabApi.main({
116
+ termfilter: JSON.parse(JSON.stringify(this.state.termfilter)),
117
+ termdbConfig: this.state.termdbConfig
118
+ });
119
+ const invalidPlots = [];
120
+ for (const [i, savedPlot] of this.state.plots.entries()) {
121
+ let plot;
122
+ try {
123
+ const _ = await importPlot(savedPlot.chartType);
124
+ plot = await _.getPlotConfig(savedPlot, this.app, this.state.activeCohort);
125
+ } catch (e) {
126
+ this.app.printError(e);
127
+ console.error(`getPlotConfig() failed: ${e}`);
128
+ }
129
+ if (!plot) {
130
+ invalidPlots.push(i);
131
+ continue;
132
+ }
133
+ this.state.plots[i] = plot;
134
+ if (!("id" in plot)) plot.id = `_AUTOID_${id++}_${i}`;
135
+ if (plot.mayAdjustConfig) {
136
+ plot.mayAdjustConfig(plot);
137
+ this.plotAdjusters.set(plot, plot.mayAdjustConfig);
138
+ delete plot.mayAdjustConfig;
139
+ }
140
+ }
141
+ if (invalidPlots.length) {
142
+ for (const i of invalidPlots) {
143
+ this.state.plots.splice(i, 1);
144
+ }
145
+ }
146
+ } catch (e) {
147
+ console.log("store.init() error", e);
148
+ throw e;
149
+ }
150
+ }
151
+ setId(item) {
152
+ item.$id = this.prevGeneratedId++;
153
+ if (item.$lst) {
154
+ for (const subitem of item.$lst) {
155
+ this.setId(subitem);
156
+ }
157
+ }
158
+ }
159
+ async setTermfilter() {
160
+ let filterUiRoot = getFilterItemByTag(this.state.termfilter.filter, "filterUiRoot");
161
+ if (!filterUiRoot) {
162
+ this.state.termfilter.filter.tag = "filterUiRoot";
163
+ filterUiRoot = this.state.termfilter.filter;
164
+ }
165
+ await Promise.all(rehydrateFilter(this.state.termfilter.filter, this.app.vocabApi));
166
+ if (!this.state.termdbConfig.selectCohort) {
167
+ this.state.activeCohort = -1;
168
+ if (this.state.activeTab === 0) this.state.activeTab = 1;
169
+ if (this.state.nav.header_mode === "with_cohortHtmlSelect") {
170
+ console.warn(`no termdbConfig.selectCohort to use for nav.header_mode = 'with_cohortHtmlSelect'`);
171
+ this.state.nav.header_mode = "search_only";
172
+ }
173
+ } else {
174
+ let cohortFilter = getFilterItemByTag(this.state.termfilter.filter, "cohortFilter");
175
+ if (!cohortFilter) {
176
+ cohortFilter = {
177
+ tag: "cohortFilter",
178
+ type: "tvs",
179
+ tvs: {
180
+ term: JSON.parse(JSON.stringify(this.state.termdbConfig.selectCohort.term)),
181
+ values: this.state.activeCohort == -1 ? [] : this.state.termdbConfig.selectCohort.values[this.state.activeCohort].keys.map((key) => {
182
+ return { key, label: key };
183
+ })
184
+ }
185
+ };
186
+ this.state.termfilter.filter = {
187
+ type: "tvslst",
188
+ in: true,
189
+ join: "and",
190
+ lst: [cohortFilter, filterUiRoot]
191
+ };
192
+ } else {
193
+ const sorter = (a, b) => a < b ? -1 : 1;
194
+ cohortFilter.tvs.values.sort((a, b) => a.key < b.key ? -1 : 1);
195
+ const keysStr = JSON.stringify(cohortFilter.tvs.values.map((v) => v.key).sort(sorter));
196
+ const i = this.state.termdbConfig.selectCohort.values.findIndex(
197
+ (v) => keysStr == JSON.stringify(v.keys.sort(sorter))
198
+ );
199
+ if (this.state.activeCohort !== -1 && this.state.activeCohort !== 0 && i !== this.state.activeCohort) {
200
+ console.log("Warning: cohortFilter will override the state.activeCohort due to mismatch");
201
+ }
202
+ this.state.activeCohort = i;
203
+ }
204
+ }
205
+ }
206
+ async rehydrateGroups() {
207
+ const lst = [];
208
+ for (const g of this.state.groups) {
209
+ lst.push(...rehydrateFilter(g.filter, this.app.vocabApi));
210
+ }
211
+ await Promise.all(lst);
212
+ }
213
+ };
214
+ MassStore.prototype.actions = {
215
+ // Type '{ app_refresh(this: MassStore, action?: {}): Promise<void>; tab_set(action: any): void; cohort_set(action: any): void; plot_prep(action: any): Promise<void>; ... 13 more ...; delete_group({ name }: { ...; }): void; }' is not assignable to type '(action: { [prop: string]: any; type: string; }) => void | Promise<void>'.
216
+ // Object literal may only specify known properties, and 'app_refresh' does not exist in type '(action: { [prop: string]: any; type: string; }) => void | Promise<void>'.
217
+ async app_refresh(action) {
218
+ this.state = this.copyMerge(this.toJson(this.state), action.state || {});
219
+ const subactionPlotIds = /* @__PURE__ */ new Set();
220
+ const promises = [];
221
+ if (action.subactions) {
222
+ for (const a of action.subactions) {
223
+ promises.push(this.actions[a.type].call(this, a));
224
+ if (a.type.startsWith("plot_")) subactionPlotIds.add(a.id);
225
+ }
226
+ }
227
+ await Promise.all(promises);
228
+ for (const plot of this.state.plots) {
229
+ const mayAdjustConfig = this.plotAdjusters.get(plot);
230
+ if (mayAdjustConfig && !subactionPlotIds.has(plot.id)) {
231
+ mayAdjustConfig(plot, action.config);
232
+ }
233
+ }
234
+ },
235
+ tab_set(action) {
236
+ this.state.nav.activeTab = action.activeTab;
237
+ },
238
+ cohort_set(action) {
239
+ this.state.activeCohort = action.activeCohort;
240
+ const cohort = this.state.termdbConfig.selectCohort.values[action.activeCohort];
241
+ const cohortFilter = getFilterItemByTag(this.state.termfilter.filter, "cohortFilter");
242
+ if (!cohortFilter) throw `No item tagged with 'cohortFilter'`;
243
+ cohortFilter.tvs.values = cohort.keys.map((key) => {
244
+ return { key, label: key };
245
+ });
246
+ },
247
+ // dispatch "plot_prep" action to produce a 'initiating' UI of this plot, for user to fill in additional details to launch the plot
248
+ // example: table, scatterplot which requires user to select two terms
249
+ async plot_prep(action) {
250
+ if (usedPlotIds.has(action.id)) delete action.id;
251
+ const plot = {
252
+ // rx.getComponents() relies on parsing dot-separated key names that breaks if a key has a dot,
253
+ // the plot.id value should be assumed to be auto-generated and to not have any non-rx usage expectations
254
+ id: "id" in action && !action.id.includes(".") ? action.id : getId()
255
+ };
256
+ usedPlotIds.add(plot.id);
257
+ if (!action.config) throw ".config{} missing for plot_prep";
258
+ if (action.config.chartType && Object.keys(action.config).length == 1) {
259
+ const _ = await importPlot(action.config.chartType);
260
+ const config = await _.getPlotConfig(action.config, this.app, this.state.activeCohort);
261
+ action.config = Object.assign(config, action.config);
262
+ }
263
+ Object.assign(plot, action.config);
264
+ this.state.plots.push(plot);
265
+ },
266
+ async plot_create(action) {
267
+ if (usedPlotIds.has(action.id)) delete action.id;
268
+ const _ = await importPlot(action.config.chartType);
269
+ const plot = await _.getPlotConfig(action.config, this.app, this.state.activeCohort);
270
+ if (!("id" in action) || action.id.includes(".")) action.id = getId();
271
+ plot.id = action.id;
272
+ usedPlotIds.add(plot.id);
273
+ if (plot.mayAdjustConfig) {
274
+ plot.mayAdjustConfig(plot);
275
+ this.plotAdjusters.set(plot, plot.mayAdjustConfig);
276
+ delete plot.mayAdjustConfig;
277
+ }
278
+ this.state.plots.push(plot);
279
+ if (plot.sections) {
280
+ for (const section of plot.sections) {
281
+ for (const p of section.plots) {
282
+ p.parentId = plot.id;
283
+ if (!p.id) p.id = getId();
284
+ const _2 = await importPlot(p.chartType);
285
+ const config = await _2.getPlotConfig(p, this.app, this.state.activeCohort);
286
+ this.state.plots.push(config);
287
+ }
288
+ }
289
+ }
290
+ },
291
+ plot_edit(action) {
292
+ const plot = this.state.plots.find((p) => p.id === action.id);
293
+ if (!plot) {
294
+ throw new CustomError(`missing plot config for id='${action.id}' in store.plot_edit()`, {
295
+ name: "MISSING_PLOT_CONFIG",
296
+ level: "warn"
297
+ });
298
+ }
299
+ this.copyMerge(plot, action.config, action.opts ? action.opts : {});
300
+ const mayAdjustConfig = this.plotAdjusters.get(plot);
301
+ if (mayAdjustConfig) mayAdjustConfig(plot, action.config);
302
+ if (action.config && "cutoff" in action.config) {
303
+ plot.cutoff = action.config.cutoff;
304
+ } else {
305
+ delete plot.cutoff;
306
+ }
307
+ if (!action.parentId && plot.parentId) action.parentId = plot.parentId;
308
+ },
309
+ plot_delete(action) {
310
+ const i = this.state.plots.findIndex((p) => p.id === action.id);
311
+ if (i !== -1) {
312
+ this.state.plots.splice(i, 1);
313
+ const plot = this.state.plots[i];
314
+ if (!action.parentId && plot?.parentId) action.parentId = plot.parentId;
315
+ }
316
+ },
317
+ plot_nestedEdits(action) {
318
+ const plot = this.state.plots.find((p) => p.id === action.id);
319
+ if (!plot) {
320
+ throw new CustomError(`missing plot config for id='${action.id}' in store.plot_edit_nested`, {
321
+ name: "MISSING_PLOT_CONFIG",
322
+ level: "warn"
323
+ });
324
+ }
325
+ for (const edit of action.edits) {
326
+ const lastKey = edit.nestedKeys.pop();
327
+ const obj = edit.nestedKeys.reduce((obj2, key) => obj2[key], plot);
328
+ obj[lastKey] = edit.value;
329
+ }
330
+ if (!action.parentId && plot.parentId) action.parentId = plot.parentId;
331
+ },
332
+ // TODO: delete this action? does not seem to be used
333
+ async plot_splice(action) {
334
+ for (const a of action.subactions) {
335
+ await this.actions[a.type].call(this, a);
336
+ }
337
+ },
338
+ filter_replace(action) {
339
+ if ("filter0" in action) {
340
+ this.state.termfilter.filter0 = action.filter0;
341
+ return;
342
+ }
343
+ const replacementFilter = action.filter ? action.filter : { type: "tvslst", join: "", in: 1, lst: [] };
344
+ if (!action.filter.tag) {
345
+ this.state.termfilter.filter = replacementFilter;
346
+ } else {
347
+ const filter = getFilterItemByTag(this.state.termfilter.filter, action.filter.tag);
348
+ if (!filter) throw `cannot replace missing filter with tag '${action.filter.tag}'`;
349
+ const parent = findParent(this.state.termfilter.filter, filter.$id);
350
+ if (parent == filter) {
351
+ this.state.termfilter.filter = replacementFilter;
352
+ } else {
353
+ const i = parent.lst.indexOf(filter);
354
+ parent.lst[i] = replacementFilter;
355
+ }
356
+ }
357
+ if (this.app.opts.app?.onFilterChange) this.app.opts.app.onFilterChange(this.state.plots);
358
+ },
359
+ cache_termq({ termId, q }) {
360
+ if (!termId) throw `missing termId for caching custom term.q`;
361
+ if (!q?.reuseId) throw `missing or empty tw.q.reuseId as cache identifier for term='${termId}'`;
362
+ const cache = this.state.reuse.customTermQ.byId;
363
+ if (!cache[termId]) cache[termId] = {};
364
+ cache[termId][q.reuseId] = q;
365
+ for (const plot of this.state.plots) {
366
+ if (!(plot.chartType in getTwsByChartType)) continue;
367
+ const twlst = getTwsByChartType[plot.chartType](plot);
368
+ for (const tw of twlst) {
369
+ if (tw?.q?.reuseId === q.reuseId) tw.q = q;
370
+ }
371
+ }
372
+ },
373
+ uncache_termq({ term, q }) {
374
+ if (!term.id) throw `missing term.id for uncaching custom term.q`;
375
+ if (!q.reuseId) throw `missing qname as uncache identifier for term.id='${term.id}'`;
376
+ const cache = this.state.reuse.customTermQ.byId[term.id];
377
+ if (!cache) throw `missing term.q cache for term.id='${term.id}`;
378
+ if (!(q.reuseId in cache)) console.warn(`q.reuseId='${q.cacheid}' not cached for term.id='${term.id}'`);
379
+ else {
380
+ delete cache[q.reuseId];
381
+ for (const plot of this.state.plots) {
382
+ if (!(plot.chartType in getTwsByChartType)) continue;
383
+ const twlst = getTwsByChartType[plot.chartType](plot);
384
+ for (const tw of twlst) {
385
+ if (tw.q.reuseId === q.reuseId) {
386
+ delete tw.q.reuseId;
387
+ delete tw.q.name;
388
+ }
389
+ }
390
+ }
391
+ }
392
+ },
393
+ add_customTerm(action) {
394
+ this.state.customTerms.push(action.obj);
395
+ },
396
+ delete_customTerm({ name }) {
397
+ const i = this.state.customTerms.findIndex((i2) => i2.name == name);
398
+ if (i != -1) this.state.customTerms.splice(i, 1);
399
+ },
400
+ add_group(action) {
401
+ if (this.state.nav.header_mode != "hidden") {
402
+ const group = action.obj;
403
+ const name = `Group ${this.state.groups.length + 1}`;
404
+ const samplelstTW = getSamplelstTW([group]);
405
+ const appGroup = {
406
+ name,
407
+ filter: getFilter(samplelstTW),
408
+ plotId: group.plotId
409
+ };
410
+ this.state.groups.push(appGroup);
411
+ this.state.nav.activeTab = 1;
412
+ } else if ("plotId" in action.obj) {
413
+ const plot = this.state.plots.find((p) => p.id == action.obj.plotId);
414
+ if (plot.groups) {
415
+ action.obj.index = plot.groups.length;
416
+ action.obj.name = `Group ${plot.groups.length + 1}`;
417
+ plot.groups.push(action.obj);
418
+ }
419
+ }
420
+ },
421
+ rename_group(action) {
422
+ const index = action.index;
423
+ const newName = action.newName;
424
+ if (this.state.nav.header_mode != "hidden") {
425
+ this.state.groups[index].name = newName;
426
+ } else {
427
+ for (const plot of this.state.plots) {
428
+ if (plot?.groups) {
429
+ plot.groups[index].name = newName;
430
+ }
431
+ }
432
+ }
433
+ },
434
+ change_color_group(action) {
435
+ const index = action.index;
436
+ const newColor = action.newColor;
437
+ if (this.state.nav.header_mode != "hidden") {
438
+ this.state.groups[index].color = newColor;
439
+ } else {
440
+ for (const plot of this.state.plots) {
441
+ if (plot?.groups) {
442
+ plot.groups[index].color = newColor;
443
+ }
444
+ }
445
+ }
446
+ },
447
+ delete_group({ name }) {
448
+ if (this.state.nav.header_mode != "hidden") {
449
+ const i = this.state.groups.findIndex((i2) => i2.name == name);
450
+ if (i != -1) this.state.groups.splice(i, 1);
451
+ } else {
452
+ for (const plot of this.state.plots) {
453
+ if (plot?.groups) {
454
+ const j = plot.groups.findIndex((j2) => j2.name == name);
455
+ if (j != -1) plot.groups.splice(j, 1);
456
+ }
457
+ }
458
+ }
459
+ }
460
+ };
461
+ var getNestedChartSeriesDataTws = (plot) => [plot.term0, plot.term, plot.term2].filter((d) => !!d);
462
+ var getTwsByChartType = {
463
+ summary: getNestedChartSeriesDataTws,
464
+ survival: getNestedChartSeriesDataTws,
465
+ cuminc: getNestedChartSeriesDataTws,
466
+ regression: (plot) => [plot.outcome, ...plot.independent].filter((d) => !!d),
467
+ matrix: (plot) => plot.termgroups.reduce((arr, grp) => {
468
+ arr.push(...grp.lst);
469
+ return arr;
470
+ }, [])
471
+ };
472
+ var storeInit = StoreApi.getInitFxn(MassStore);
473
+
474
+ export {
475
+ storeInit
476
+ };
477
+ //# sourceMappingURL=chunk-HKSNADSX.js.map
@@ -0,0 +1,129 @@
1
+ import {
2
+ keyupEnter
3
+ } from "./chunk-SA7APTJR.js";
4
+
5
+ // src/block.mds.svcnv.share.js
6
+ function rnabamtk_initparam(c) {
7
+ if (!c.dna_mintotalreads) c.dna_mintotalreads = 8;
8
+ if (!c.rna_mintotalreads) c.rna_mintotalreads = 8;
9
+ if (!c.hetsnp_minbaf) c.hetsnp_minbaf = 0.3;
10
+ if (!c.hetsnp_maxbaf) c.hetsnp_maxbaf = 0.7;
11
+ if (c.rnapileup_q == void 0) c.rnapileup_q = 0;
12
+ if (!c.rnapileup_Q) c.rnapileup_Q = 13;
13
+ if (!c.binompvaluecutoff) c.binompvaluecutoff = 0.05;
14
+ if (!c.clientcolor_snpinuse) c.clientcolor_snpinuse = "blue";
15
+ if (!c.clientcolor_markernotinuse) c.clientcolor_markernotinuse = "#bbb";
16
+ }
17
+ function configPanel_rnabam(tk, block, loadTk) {
18
+ const c = tk.checkrnabam;
19
+ if (!c) return;
20
+ tk.tkconfigtip.d.append("hr");
21
+ const d = tk.tkconfigtip.d.append("div").style("margin", "15px 0px");
22
+ d.append("div").style("opacity", 0.5).style("font-size", ".9em").text("Finding heterozygous SNPs in DNA");
23
+ {
24
+ const row = d.append("div").style("margin-top", "5px");
25
+ row.append("span").html("DNA minimum total read count&nbsp;");
26
+ row.append("input").attr("type", "number").style("width", "50px").property("value", c.dna_mintotalreads).on("keyup", (event) => {
27
+ if (!keyupEnter(event)) return;
28
+ let v = Number.parseInt(event.target.value);
29
+ if (!v || v <= 0) return;
30
+ if (c.dna_mintotalreads == v) {
31
+ return;
32
+ }
33
+ c.dna_mintotalreads = v;
34
+ loadTk(tk, block);
35
+ });
36
+ row.append("div").style("opacity", ".5").style("font-size", ".8em").text("If a SNP's total coverage is below cutoff, it will be skipped.");
37
+ }
38
+ {
39
+ const row = d.append("div").style("margin-top", "5px");
40
+ row.append("span").html("Heterozygous SNP BAF range&nbsp;&nbsp;");
41
+ row.append("input").attr("type", "number").style("width", "50px").property("value", c.hetsnp_minbaf).on("keyup", (event) => {
42
+ if (!keyupEnter(event)) return;
43
+ let v = Number.parseFloat(event.target.value);
44
+ if (!v || v <= 0) return;
45
+ if (c.hetsnp_minbaf == v) {
46
+ return;
47
+ }
48
+ c.hetsnp_minbaf = v;
49
+ loadTk(tk, block);
50
+ });
51
+ row.append("span").style("opacity", ".5").style("font-size", ".8em").html("&nbsp;&leq; BAF &leq;&nbsp;");
52
+ row.append("input").attr("type", "number").style("width", "50px").property("value", c.hetsnp_maxbaf).on("keyup", (event) => {
53
+ if (!keyupEnter(event)) return;
54
+ let v = Number.parseFloat(event.target.value);
55
+ if (!v || v <= 0) return;
56
+ if (c.hetsnp_maxbaf == v) {
57
+ return;
58
+ }
59
+ c.hetsnp_maxbaf = v;
60
+ loadTk(tk, block);
61
+ });
62
+ row.append("div").style("opacity", ".5").style("font-size", ".8em").text("If a SNP's BAF (B-allele fraction) is within this range, it is heterozygous.");
63
+ }
64
+ d.append("div").style("margin-top", "20px").style("opacity", 0.5).style("font-size", ".9em").text("Counting alleles in RNA-seq BAM file");
65
+ {
66
+ const row = d.append("div").style("margin-top", "5px");
67
+ row.append("span").html("Skip alignments with mapQ smaller than&nbsp;");
68
+ row.append("input").attr("type", "number").style("width", "50px").property("value", c.rnapileup_q).on("keyup", (event) => {
69
+ if (!keyupEnter(event)) return;
70
+ let v = Number.parseInt(event.target.value);
71
+ if (!v || v < 0) return;
72
+ if (c.rnapileup_q == v) {
73
+ return;
74
+ }
75
+ c.rnapileup_q = v;
76
+ loadTk(tk, block);
77
+ });
78
+ }
79
+ {
80
+ const row = d.append("div").style("margin-top", "5px");
81
+ row.append("span").html("Skip bases with baseQ/BAQ smaller than&nbsp;");
82
+ row.append("input").attr("type", "number").style("width", "50px").property("value", c.rnapileup_Q).on("keyup", (event) => {
83
+ if (!keyupEnter(event)) return;
84
+ let v = Number.parseInt(event.target.value);
85
+ if (!v || v <= 0) return;
86
+ if (c.rnapileup_Q == v) {
87
+ return;
88
+ }
89
+ c.rnapileup_Q = v;
90
+ loadTk(tk, block);
91
+ });
92
+ }
93
+ d.append("div").style("margin-top", "20px").style("opacity", 0.5).style("font-size", ".9em").text("Binomial test on whether a heterozygous SNP shows allelic bias in RNA");
94
+ {
95
+ const row = d.append("div").style("margin-top", "5px");
96
+ row.append("span").html("P-value cutoff&nbsp;");
97
+ row.append("input").attr("type", "number").style("width", "50px").property("value", c.binompvaluecutoff).on("keyup", (event) => {
98
+ if (!keyupEnter(event)) return;
99
+ let v = Number.parseFloat(event.target.value);
100
+ if (!v || v <= 0 || v >= 1) return;
101
+ if (c.binompvaluecutoff == v) {
102
+ return;
103
+ }
104
+ c.binompvaluecutoff = v;
105
+ loadTk(tk, block);
106
+ });
107
+ }
108
+ {
109
+ const row = d.append("div").style("margin-top", "5px");
110
+ row.append("span").html("RNA minimum total read count&nbsp;");
111
+ row.append("input").attr("type", "number").style("width", "50px").property("value", c.rna_mintotalreads).on("keyup", (event) => {
112
+ if (!keyupEnter(event)) return;
113
+ let v = Number.parseInt(event.target.value);
114
+ if (!v || v <= 0) return;
115
+ if (c.rna_mintotalreads == v) {
116
+ return;
117
+ }
118
+ c.rna_mintotalreads = v;
119
+ loadTk(tk, block);
120
+ });
121
+ row.append("div").style("opacity", ".5").style("font-size", ".8em").text("If a SNP's total read count from RNA is below cutoff, it won't do binomial test.");
122
+ }
123
+ }
124
+
125
+ export {
126
+ rnabamtk_initparam,
127
+ configPanel_rnabam
128
+ };
129
+ //# sourceMappingURL=chunk-I5RAQKKJ.js.map