@sjcrh/proteinpaint-client 2.191.3 → 2.191.4

package/dist/chunk-322QC6R4.js

@@ -0,0 +1,222 @@
+import {
+  appInit
+} from "./chunk-N2SKTCDK.js";
+import {
+  getDefaultViolinSettings
+} from "./chunk-FFEIP5CT.js";
+import {
+  select_default
+} from "./chunk-I6Y4O3RR.js";
+
+// plots/regression.inputs.values.table.js
+var row_hover_bgcolor = "#fff6dc";
+var InputValuesTable = class {
+  constructor(opts) {
+    this.opts = opts;
+    this.input = opts.input;
+    setRenderers(this);
+    this.setDOM(opts.holder);
+  }
+  main() {
+    try {
+      const term = this.input.term;
+      if (!term || !this.input.termStatus) {
+        this.dom.holder.style("display", "none");
+        this.dom.loading_div.style("display", "none");
+        return;
+      } else if (term) {
+        this.dom.holder.style("display", "block");
+        this.dom.loading_div.style("display", "block");
+        this.updateValueCount();
+        this.dom.loading_div.style("display", "none");
+        this.render();
+        return;
+      }
+    } catch (e) {
+      this.dom.loading_div.style("display", "none");
+      throw e;
+    }
+  }
+  updateValueCount() {
+    const i = this.input;
+    try {
+      if (i.pill && i.pill.validateQ) {
+        i.pill.validateQ({
+          term: i.term.term,
+          q: i.term.q,
+          sampleCounts: i.termStatus.sampleCounts
+        });
+      }
+    } catch (e) {
+      i.term.error = e;
+    }
+  }
+};
+function setRenderers(self) {
+  self.setDOM = (holder) => {
+    self.dom = {
+      holder: holder.style("margin", "10px").style("font-size", ".8em").style("text-align", "left").style("color", "#999"),
+      loading_div: holder.append("div").text("Loading..").style("display", "none"),
+      top_info_div: holder.append("div").style("padding-bottom", "5px"),
+      violin_div: holder.append("div").style("color", "black").style("padding-top", "5px"),
+      table_div: holder.append("table").style("margin", "5px 0px 15px 0px").style("border-collapse", "collapse").style("color", "black"),
+      bottom_info_div: holder.append("div"),
+      excluded_div: holder.append("table").style("display", "none").style("margin", "5px 10px").style("border-collapse", "collapse")
+    };
+  };
+  self.render = async () => {
+    const input = self.input;
+    renderTopInfo(input);
+    await renderValuesTable(input);
+    renderBottomInfo(input);
+    renderExcludedValues(input);
+  };
+  function renderTopInfo(input) {
+    if (input.termStatus.topInfoStatus?.length) {
+      self.dom.top_info_div.style("display", "block").html(input.termStatus.topInfoStatus.join("<br>"));
+    } else {
+      self.dom.top_info_div.style("display", "none");
+    }
+  }
+  async function renderValuesTable(input) {
+    if (input.term.q.mode == "continuous" || input.term.q.mode == "spline") {
+      self.dom.violin_div.style("display", "block");
+      self.dom.table_div.style("display", "none");
+      if (self.plotAppApi) {
+        const action = {
+          type: "app_refresh",
+          state: { termfilter: structuredClone(self.input.parent.state?.termfilter) },
+          subactions: [
+            {
+              type: "plot_edit",
+              id: self.violinApi.id,
+              config: {
+                term: input.term
+              }
+            }
+          ]
+        };
+        self.plotAppApi.dispatch(action);
+      } else {
+        const opts = {
+          holder: self.dom.violin_div,
+          vocabApi: self.input.parent.app.vocabApi,
+          state: {
+            vocab: {
+              genome: self.input.parent.app.vocabApi.genome,
+              dslabel: self.input.parent.app.vocabApi.dslabel
+            },
+            termfilter: structuredClone(self.input.parent.state?.termfilter),
+            plots: [
+              {
+                chartType: "violin",
+                term: input.term,
+                settings: {
+                  violin: getDefaultViolinSettings(null, {
+                    svgw: 350,
+                    axisHeight: 25,
+                    rightMargin: 10,
+                    datasymbol: "rug",
+                    radius: 8,
+                    plotThickness: 80
+                  })
+                }
+              }
+            ]
+          },
+          // global options for plotAppApi
+          // opts.violin will apply to all violin plots within the plotApp
+          // rx will pass options by component type, which are not tracked in state
+          // examples are callbacks, event listeners, etc
+          violin: {
+            mode: "minimal"
+          }
+        };
+        self.plotAppApi = await appInit(opts);
+        const plotId = self.plotAppApi.getState().plots[0].id;
+        self.violinApi = self.plotAppApi.getComponents(`plots.${plotId}`);
+      }
+    } else {
+      self.dom.violin_div.style("display", "none");
+      const data = input.termStatus.sampleCounts;
+      if (!data || !data.length) {
+        self.dom.table_div.style("display", "none");
+        return;
+      }
+      self.dom.table_div.style("display", "block");
+      const l = self.input.orderedLabels;
+      const sortFxn = l && l.length ? (a, b) => l.indexOf(a.label) - l.indexOf(b.label) : (a, b) => b.samplecount - a.samplecount;
+      const tr_data = data.sort(sortFxn);
+      const maxCount = Math.max(...tr_data.map((v) => v.samplecount), 0);
+      tr_data.forEach((v) => v.bar_width_frac = Number((1 - (maxCount - v.samplecount) / maxCount).toFixed(4)));
+      self.dom.table_div.selectAll("tr").remove();
+      const trs = self.dom.table_div.selectAll("tr").data(tr_data, (b) => b.key);
+      trs.enter().append("tr").each(trEnter);
+    }
+  }
+  function renderBottomInfo(input) {
+    if (input.termStatus.bottomSummaryStatus) {
+      self.dom.bottom_info_div.style("display", "block").html(input.termStatus.bottomSummaryStatus);
+    } else {
+      self.dom.bottom_info_div.style("display", "none");
+    }
+  }
+  function renderExcludedValues(input) {
+    const data = input.termStatus.excludeCounts;
+    if (!data || !data.length) {
+      self.dom.excluded_div.style("display", "none");
+      return;
+    }
+    self.dom.excluded_div.style("display", "block").selectAll("tr").remove();
+    const trs = self.dom.excluded_div.selectAll("tr").data(data, (b) => b.key);
+    trs.enter().append("tr").each(trEnter);
+    self.dom.excluded_div.selectAll("td").style("color", "#999");
+  }
+  function trEnter(item) {
+    const tr = select_default(this);
+    const input = this.parentNode.__data__;
+    const t = input.term;
+    const maxBarWidth = 150;
+    tr.style("text-align", "left").style("cursor", input.termStatus.allowToSelectRefGrp ? "pointer" : "default");
+    const tdSpacing = "1px 10px 1px 0px";
+    tr.append("td").style("padding", tdSpacing).style("text-align", "left").style("color", "black").text(item.samplecount !== void 0 ? "n=" + item.samplecount : "");
+    tr.append("td").style("padding", tdSpacing).style("text-align", "left").style("color", "black").text(item.label);
+    const bar_td = tr.append("td").style("padding", tdSpacing);
+    const barWidth = maxBarWidth * item.bar_width_frac;
+    bar_td.append("div").style("margin", tdSpacing).style("width", barWidth + "px").style("height", "15px").style("background-color", "#ddd");
+    addTrBehavior({ input, item, tr, rendered: false });
+  }
+  function addTrBehavior({ input, item, tr, rendered }) {
+    if (!item.bar_width_frac) return;
+    const t = input.term;
+    const hover_flag = input.termStatus.allowToSelectRefGrp;
+    let ref_text;
+    if (rendered) {
+      tr.style("background", "white");
+      ref_text = select_default(tr.node().lastChild).select("div").style("display", item.key === t.refGrp && hover_flag ? "inline-block" : "none").style("border", item.key === t.refGrp && hover_flag ? "1px solid #bbb" : "");
+    } else if (input.term.q.mode != "cutoff") {
+      const reference_td = tr.append("td").style("padding", "1px 5px").style("text-align", "left");
+      ref_text = reference_td.append("div").style("display", item.key === t.refGrp && hover_flag ? "inline-block" : "none").style("padding", "2px 10px").style("border", item.key === t.refGrp && hover_flag ? "1px solid #bbb" : "").style("border-radius", "10px").style("color", "#999").style("font-size", ".7em").text("REFERENCE");
+      if (hover_flag) {
+        tr.on("mouseover", () => {
+          if (t.refGrp !== item.key) {
+            tr.style("background", row_hover_bgcolor);
+            ref_text.style("display", "inline-block").style("border", "").text("Set as reference");
+          } else tr.style("background", "white");
+        }).on("mouseout", () => {
+          tr.style("background", "white");
+          if (t.refGrp !== item.key) ref_text.style("display", "none");
+        }).on("click", () => {
+          t.refGrp = item.key;
+          ref_text.style("border", "1px solid #bbb").text("REFERENCE");
+          self.opts.callback(t);
+        });
+      }
+    }
+  }
+}
+
+export {
+  InputValuesTable
+};
+//# sourceMappingURL=chunk-322QC6R4.js.map

package/dist/chunk-35SCELN4.js

@@ -0,0 +1,217 @@
+import {
+  dofetch,
+  dofetch2
+} from "./chunk-7EMWHCVW.js";
+import {
+  contigNameNoChr2
+} from "./chunk-4UWS5Y3N.js";
+
+// tracks/hic/data/parseData.ts
+async function hicParseFile(hic, debugmode, errList = []) {
+  if (debugmode) window["hic"] = hic;
+  if (hic.tklst) {
+    const lst = [];
+    for (const t of hic.tklst) {
+      if (!t.type) {
+        errList.push("type missing from one of the tracks accompanying HiC");
+      } else {
+        t.iscustom = true;
+        lst.push(t);
+      }
+    }
+    if (lst.length) {
+      hic.tklst = lst;
+    } else {
+      delete hic.tklst;
+    }
+  }
+  if (hic.enzyme) {
+    if (hic.genome.hicenzymefragment) {
+      let frag = null;
+      for (const f of hic.genome.hicenzymefragment) {
+        if (f.enzyme == hic.enzyme) {
+          frag = f;
+          break;
+        }
+      }
+      if (frag) {
+        hic.enzymefile = frag.file;
+      } else {
+        errList.push("unknown enzyme: " + hic.enzyme);
+        delete hic.enzyme;
+      }
+    } else {
+      errList.push("no enzyme fragment information available for this genome");
+      delete hic.enzyme;
+    }
+  }
+  try {
+    if (hic.sv && hic.sv.file) {
+      const re = await dofetch(hic.hostURL + "/textfile", {
+        method: "POST",
+        body: JSON.stringify({ file: hic.sv.file, jwt: hic.jwt })
+      });
+      const data2 = re.json();
+      const [err2, header, items] = parseSV(data2.text);
+      if (err2) throw { message: "Error parsing SV: " + err2 };
+      hic.sv.header = header;
+      hic.sv.items = items;
+    }
+    const data = await dofetch2("hicstat?" + (hic.file ? "file=" + hic.file : "url=" + hic.url));
+    if (data.error) {
+      errList.push(data.error);
+      return;
+    }
+    const err = hicparsestat(hic, data.out);
+    if (err) throw { message: err };
+  } catch (err) {
+    errList.push(err.message || err);
+    if (err.stack) {
+      console.log(err.stack);
+    }
+  }
+  return hic;
+}
+function parseSV(txt) {
+  const lines = txt.trim().split(/\r?\n/);
+  const [err, header] = parseSVheader(lines[0]);
+  if (err) return ["header error: " + err];
+  const items = [];
+  for (let i = 1; i < lines.length; i++) {
+    const line = lines[i];
+    if (line[0] == "#") continue;
+    const [e, m] = parseSVline(line, header);
+    if (e) return ["line " + (i + 1) + " error: " + e];
+    items.push(m);
+  }
+  return [null, header, items];
+}
+function parseSVheader(line) {
+  const header = line.toLowerCase().split("	");
+  if (header.length <= 1) return "invalid file header for fusions";
+  const htry = (...lst) => {
+    for (const a of lst) {
+      const j = header.indexOf(a);
+      if (j != -1) return j;
+    }
+    return -1;
+  };
+  let i = htry("chr_a", "chr1", "chra");
+  if (i == -1) return "chr_A missing from header";
+  header[i] = "chr1";
+  i = htry("chr_b", "chr2", "chrb");
+  if (i == -1) return "chr_B missing from header";
+  header[i] = "chr2";
+  i = htry("pos_a", "position_a", "position1", "posa");
+  if (i == -1) return "pos_a missing from header";
+  header[i] = "position1";
+  i = htry("pos_b", "position_b", "position2", "posb");
+  if (i == -1) return "pos_b missing from header";
+  header[i] = "position2";
+  i = htry("strand_a", "orta", "orienta");
+  if (i == -1) return "strand_a missing from header";
+  header[i] = "strand1";
+  i = htry("strand_b", "ortb", "orientb");
+  if (i == -1) return "strand_b missing from header";
+  header[i] = "strand2";
+  i = htry("numreadsa");
+  if (i != -1) header[i] = "reads1";
+  i = htry("numreadsb");
+  if (i != -1) header[i] = "reads2";
+  return [null, header];
+}
+function parseSVline(line, header) {
+  const lst = line.split("	");
+  const m = {};
+  for (let j = 0; j < header.length; j++) {
+    m[header[j]] = lst[j];
+  }
+  if (!m.chr1) return ["missing chr1"];
+  if (m.chr1.toLowerCase().indexOf("chr") != 0) {
+    m.chr1 = "chr" + m.chr1;
+  }
+  if (!m.chr2) return ["missing chr2"];
+  if (m.chr2.toLowerCase().indexOf("chr") != 0) {
+    m.chr2 = "chr" + m.chr2;
+  }
+  if (!m.position1) return ["missing position1"];
+  let v = Number.parseInt(m.position1);
+  if (Number.isNaN(v) || v <= 0) return ["position1 invalid value"];
+  m.position1 = v;
+  if (!m.position2) return ["missing position2"];
+  v = Number.parseInt(m.position2);
+  if (Number.isNaN(v) || v <= 0) return ["position2 invalid value"];
+  m.position2 = v;
+  if (m.reads1) {
+    v = Number.parseInt(m.reads1);
+    if (Number.isNaN(v)) return ["reads1 invalid value"];
+    m.reads1 = v;
+  }
+  if (m.reads2) {
+    v = Number.parseInt(m.reads2);
+    if (Number.isNaN(v)) return ["reads2 invalid value"];
+    m.reads2 = v;
+  }
+  return [null, m];
+}
+function hicparsestat(hic, j) {
+  if (!j) return "cannot stat hic file";
+  hic.normalization = j.normalization;
+  hic.version = j.version;
+  if (!j.Chromosomes) return "Chromosomes not found in file stat";
+  if (!Array.isArray(j.chrorder)) return ".chrorder[] missing";
+  if (j.chrorder.length == 0) return ".chrorder[] empty array";
+  hic.chrorder = j.chrorder;
+  if (!j["Base pair-delimited resolutions"]) return "Base pair-delimited resolutions not found in file stat";
+  if (!Array.isArray(j["Base pair-delimited resolutions"])) return "Base pair-delimited resolutions should be array";
+  hic.bpresolution = j["Base pair-delimited resolutions"];
+  if (!j["Fragment-delimited resolutions"]) return "Fragment-delimited resolutions not found in file stat";
+  if (!Array.isArray(j["Fragment-delimited resolutions"])) return "Fragment-delimited resolutions is not array";
+  hic.fragresolution = j["Fragment-delimited resolutions"];
+  const chrlst = [];
+  for (const chr in j.Chromosomes) {
+    chrlst.push(chr);
+  }
+  const [nochrcount, haschrcount] = contigNameNoChr2(hic.genome, chrlst);
+  if (nochrcount + haschrcount == 0) return "chromosome names do not match with genome build";
+  if (nochrcount > 0) {
+    hic.nochr = true;
+    for (let i = 0; i < hic.chrorder.length; i++) hic.chrorder[i] = "chr" + hic.chrorder[i];
+  }
+  hic.chrlst = [];
+  for (const chr of hic.genome.majorchrorder) {
+    const c2 = hic.nochr ? chr.replace("chr", "") : chr;
+    if (chrlst.indexOf(c2) != -1) {
+      hic.chrlst.push(chr);
+    }
+  }
+}
+function hicparsefragdata(items) {
+  const id2coord = /* @__PURE__ */ new Map();
+  let min = null, max;
+  for (const i of items) {
+    if (!i.rest || !i.rest[0]) {
+      return ["items[].rest data problem"];
+    }
+    const id = Number.parseInt(i.rest[0]);
+    if (Number.isNaN(id)) {
+      return [i.start + "." + i.stop + " invalid fragment id: " + i.rest[0]];
+    }
+    id2coord.set(id, [i.start, i.stop]);
+    if (min == null) {
+      min = id;
+      max = id;
+    } else {
+      min = Math.min(min, id);
+      max = Math.max(max, id);
+    }
+  }
+  return [null, id2coord, min, max];
+}
+
+export {
+  hicParseFile,
+  hicparsestat,
+  hicparsefragdata
+};
+//# sourceMappingURL=chunk-35SCELN4.js.map