@sjcrh/proteinpaint-client 2.182.0 → 2.183.0

package/dist/scatter.integration.spec-6KRDNHHH.js

@@ -0,0 +1,1194 @@
+import {
+  getGeneVariantTw,
+  getGenesetMutTw,
+  getScctTw,
+  getScgeneexpTw,
+  getSsgseaTw
+} from "./chunk-BAY47D5E.js";
+import {
+  getRunPp,
+  rideInit
+} from "./chunk-E4NVHKWD.js";
+import {
+  detectAttr,
+  detectChildAttr,
+  detectChildStyle,
+  detectGte,
+  detectLst,
+  detectStyle,
+  sleep
+} from "./chunk-ZIBWLDQI.js";
+import {
+  require_tape
+} from "./chunk-QWOE5YTB.js";
+import "./chunk-I4IKRKYJ.js";
+import "./chunk-4RR4KPRJ.js";
+import "./chunk-V245THQC.js";
+import "./chunk-DGMK7SXX.js";
+import "./chunk-PRZWSBMA.js";
+import "./chunk-YY4CKQJ6.js";
+import "./chunk-MKAF2BHB.js";
+import "./chunk-OSM7YS23.js";
+import "./chunk-S5ZI6N2I.js";
+import "./chunk-AQ4OP4GR.js";
+import {
+  getSamplelstTW,
+  openPlot,
+  openSummaryPlot
+} from "./chunk-OXJ2TWDO.js";
+import "./chunk-HJ6L54YS.js";
+import "./chunk-V6DLLX4N.js";
+import "./chunk-7RN3L2BX.js";
+import "./chunk-A6TQGNDQ.js";
+import "./chunk-HYZG6OPC.js";
+import "./chunk-FN5XPUPH.js";
+import "./chunk-LSEFWW72.js";
+import "./chunk-5EF5U7MX.js";
+import "./chunk-2K5DSRBJ.js";
+import "./chunk-UCLS2SVB.js";
+import "./chunk-MVTCBVSX.js";
+import "./chunk-SEQLC4AD.js";
+import "./chunk-L4QG7XZE.js";
+import "./chunk-DQC5FFGV.js";
+import "./chunk-KQMEJUWI.js";
+import "./chunk-UJU3Q7QJ.js";
+import "./chunk-WGL6FIUE.js";
+import "./chunk-6ITDJ5UR.js";
+import {
+  mclass
+} from "./chunk-XYFDBYOY.js";
+import "./chunk-TV74I3Y5.js";
+import "./chunk-IH7ILDJS.js";
+import "./chunk-LOZEKOES.js";
+import "./chunk-TOU7EVFQ.js";
+import "./chunk-OAWQ6LOO.js";
+import "./chunk-SEEYV6P2.js";
+import {
+  select_default
+} from "./chunk-NDWTN4U5.js";
+import {
+  rgb
+} from "./chunk-OMR2DT66.js";
+import {
+  __toESM
+} from "./chunk-HFNDKYVF.js";
+
+// plots/scatter/test/scatter.integration.spec.js
+var import_tape = __toESM(require_tape(), 1);
+var runpp = getRunPp("mass", {
+  state: {
+    nav: { activeTab: 1 },
+    vocab: {
+      dslabel: "TermdbTest",
+      genome: "hg38-test"
+    }
+  },
+  debug: 1
+});
+var state = {
+  plots: [
+    {
+      chartType: "sampleScatter",
+      colorTW: { id: "diaggrp" },
+      name: "TermdbTest TSNE"
+    }
+  ]
+};
+var open_state = {
+  nav: { header_mode: "hide_search" },
+  plots: [
+    {
+      chartType: "sampleScatter",
+      colorTW: { id: "diaggrp" },
+      name: "TermdbTest TSNE"
+    }
+  ]
+};
+var state3D = {
+  plots: [
+    {
+      chartType: "sampleScatter",
+      colorTW: { id: "diaggrp" },
+      name: "TermdbTest TSNE",
+      term0: { id: "agedx", q: { mode: "continuous" } }
+    }
+  ]
+};
+var stateDynamicScatter = {
+  plots: [
+    {
+      chartType: "sampleScatter",
+      colorTW: { id: "diaggrp" },
+      term: { id: "agedx", q: { mode: "continuous" } },
+      term2: { id: "hrtavg", q: { mode: "continuous" } }
+    }
+  ]
+};
+var state2geneexp = {
+  plots: [
+    {
+      chartType: "sampleScatter",
+      colorTW: { id: "diaggrp" },
+      term: { term: { type: "geneExpression", gene: "AKT1" }, q: { mode: "continuous" } },
+      term2: { term: { type: "geneExpression", gene: "TP53" }, q: { mode: "continuous" } }
+    }
+  ]
+};
+var state2ssgsea = {
+  plots: [
+    {
+      chartType: "sampleScatter",
+      colorTW: { id: "diaggrp" },
+      term: { term: { type: "ssGSEA", id: "HALLMARK_ADIPOGENESIS" }, q: { mode: "continuous" } },
+      term2: { term: { type: "ssGSEA", id: "HALLMARK_ALLOGRAFT_REJECTION" }, q: { mode: "continuous" } }
+    }
+  ]
+};
+var state2dnameth = {
+  plots: [
+    {
+      chartType: "sampleScatter",
+      colorTW: { id: "diaggrp" },
+      term: {
+        term: { type: "dnaMethylation", chr: "chr17", start: 7673484, stop: 7681953, genomicFeatureType: "gene" },
+        q: { mode: "continuous" }
+      },
+      term2: {
+        term: { type: "dnaMethylation", chr: "chr17", start: 7663195, stop: 7671664, genomicFeatureType: "gene" },
+        q: { mode: "continuous" }
+      }
+    }
+  ]
+};
+var state2scgeneexp = {
+  plots: [
+    {
+      chartType: "sampleScatter",
+      term: getScgeneexpTw(),
+      term2: getScgeneexpTw("TP53")
+    }
+  ]
+};
+var state3DContour = {
+  plots: [
+    {
+      chartType: "sampleScatter",
+      colorTW: { id: "diaggrp" },
+      name: "TermdbTest TSNE",
+      term0: { id: "agedx", q: { mode: "continuous" } },
+      settings: { sampleScatter: { showContour: true } }
+    }
+  ]
+};
+var groups = [
+  {
+    name: "Test group 1",
+    items: [
+      {
+        sample: "2646",
+        x: -103.141543,
+        y: 73.31223702,
+        sampleId: 41,
+        category_info: {},
+        hidden: {
+          category: false
+        },
+        category: '"Acute lymphoblastic leukemia"',
+        shape: "Ref"
+      },
+      {
+        sample: "2800",
+        x: -99.20065673,
+        y: 73.64971694,
+        sampleId: 52,
+        category_info: {},
+        hidden: {
+          category: false
+        },
+        category: '"Acute lymphoblastic leukemia"',
+        shape: "Ref"
+      }
+    ],
+    index: 1
+  }
+];
+function getHolder() {
+  return select_default("body").append("div");
+}
+(0, import_tape.default)("\n", function(test) {
+  test.comment("-***- plots/sampleScatter -***-");
+  test.end();
+});
+(0, import_tape.default)("Render TermdbTest scatter plot and open survival and summary", function(test) {
+  test.timeoutAfter(8e3);
+  test.plan(7);
+  const holder = getHolder();
+  runpp({
+    holder,
+    //Fix for test failing because survival & summary sandboxs are not destroyed.
+    state,
+    sampleScatter: {
+      callbacks: {
+        "postRender.test": runTests
+      }
+    }
+  });
+  async function runTests(scatter) {
+    const scatterDiv = scatter.Inner.model.charts[0].chartDiv;
+    testPlot();
+    testLegendTitle();
+    const group = await testCreateGroup();
+    const tw = getSamplelstTW([group]);
+    await testOpenSurvivalPlot();
+    await testOpenSummaryPlot();
+    if (test._ok) holder.remove();
+    test.end();
+    function testPlot() {
+      const serieG = scatterDiv.select(".sjpcb-scatter-series");
+      const numSymbols = serieG.selectAll("path").size();
+      test.equal(
+        numSymbols,
+        scatter.Inner.model.charts[0].data.samples.length,
+        `Should be ${scatter.Inner.model.charts[0].data.samples.length}. Rendered ${numSymbols} symbols.`
+      );
+    }
+    function testLegendTitle() {
+      const g = scatterDiv.select(".sjpcb-scatter-legend");
+      test.true(g != null, "Should have a legend");
+      const texts = g.selectAll('text[data-testid="legendTitle"]');
+      test.true(
+        texts._groups[0][0].innerHTML.startsWith(scatter.Inner.config.colorTW.term.name),
+        "colorTW legend title made"
+      );
+      test.true(
+        texts._groups[0][1].innerHTML.startsWith(scatter.Inner.config.shapeTW.term.name),
+        "shapeTW legend title made"
+      );
+    }
+    async function testCreateGroup() {
+      const samples = scatterDiv.select(".sjpcb-scatter-series").selectAll("path").nodes().filter((p) => p.__data__?.category === "Acute lymphoblastic leukemia").map((path) => path.__data__);
+      test.equal(samples.length, 36, `Group should have 36 symbols.`);
+      const self = scatter.Inner;
+      const group2 = {
+        name: `Group 1`,
+        items: samples,
+        index: 0
+      };
+      self.config.groups.push(group2);
+      return group2;
+    }
+    async function testOpenSurvivalPlot() {
+      const plots = scatter.Inner.app.getState().plots;
+      const elem = scatter.Inner.app.Inner.dom.plotDiv.node();
+      const preSandboxes = [...elem.querySelectorAll(".sjpp-sandbox")];
+      const sandboxes = await detectLst({
+        elem,
+        selector: ".sjpp-sandbox",
+        count: plots.length + 1,
+        async trigger() {
+          const survivalTerm = await scatter.Inner.app.vocabApi.getterm("efs");
+          await openPlot("survival", survivalTerm, tw, scatter.Inner.app);
+        }
+      });
+      const newSandbox = sandboxes.find((s) => !preSandboxes.includes(s));
+      test.equal(
+        [...newSandbox.querySelectorAll(".sja_errorbar")].filter((b) => b.style.display != "none").length,
+        0,
+        'Should render survival plot without errors".'
+      );
+    }
+    async function testOpenSummaryPlot() {
+      const plots = scatter.Inner.app.getState().plots;
+      const elem = scatter.Inner.app.Inner.dom.plotDiv.node();
+      const preSandboxes = [...elem.querySelectorAll(".sjpp-sandbox")];
+      const survivalTerm = await scatter.Inner.app.vocabApi.getterm("efs");
+      const sandboxes = await detectLst({
+        elem,
+        selector: ".sjpp-sandbox",
+        count: plots.length + 1,
+        async trigger() {
+          const genderTerm = await scatter.Inner.app.vocabApi.getterm("sex");
+          await openSummaryPlot(genderTerm, tw, scatter.Inner.app);
+        }
+      });
+      const newSandbox = sandboxes.find((s) => !preSandboxes.includes(s));
+      test.equal(
+        [...newSandbox.querySelectorAll(".sja_errorbar")].filter((b) => b.style.display != "none").length,
+        0,
+        'Should render summary plot without errors".'
+      );
+    }
+  }
+});
+(0, import_tape.default)("Render TermdbTest scatter plot adding age as Z to render a 3D plot", function(test) {
+  test.timeoutAfter(8e3);
+  test.plan(1);
+  const holder = getHolder();
+  runpp({
+    holder,
+    //Fix for test failing because survival & summary sandboxs are not destroyed.
+    state: state3D,
+    sampleScatter: {
+      callbacks: {
+        "postRender.test": runTests
+      }
+    }
+  });
+  async function runTests(scatter) {
+    const is3D = scatter.Inner.model.is3D;
+    const scatterDiv = scatter.Inner.model.charts[0].chartDiv;
+    test.true(is3D, "Should be a 3D scatter plot");
+    if (test._ok) holder.remove();
+    test.end();
+  }
+});
+(0, import_tape.default)("Render 3D plot with age as Z and showContour set to true to apply contour on 3D plot", function(test) {
+  test.timeoutAfter(8e3);
+  test.plan(1);
+  const holder = getHolder();
+  runpp({
+    holder,
+    //Fix for test failing because survival & summary sandboxs are not destroyed.
+    state: state3DContour,
+    sampleScatter: {
+      callbacks: {
+        "postRender.test": runTests
+      }
+    }
+  });
+  async function runTests(scatter) {
+    const chart = scatter.Inner.model.charts[0];
+    await sleep(1e3);
+    test.true(chart.plane != null, "Should have a plane with the contour map");
+    if (test._ok) holder.remove();
+    test.end();
+  }
+});
+(0, import_tape.default)("dynamic scatter of agedx & hrtavg", function(test) {
+  test.timeoutAfter(8e3);
+  test.plan(2);
+  const holder = getHolder();
+  runpp({
+    holder,
+    state: stateDynamicScatter,
+    sampleScatter: {
+      callbacks: {
+        "postRender.test": runTests
+      }
+    }
+  });
+  async function runTests(scatter) {
+    scatter.on("postRender.test", null);
+    const chart = scatter.Inner.model.charts[0];
+    test.true(scatter.Inner.settings.showAxes, "Dynamic scatter should have axes");
+    scatter.Inner.settings.showContour = true;
+    await scatter.Inner.app.dispatch({
+      type: "plot_edit",
+      id: scatter.Inner.id,
+      config: { settings: { sampleScatter: scatter.Inner.settings } }
+    });
+    const contourG = scatter.Inner.model.charts[0].chartDiv.select('g[stroke-linejoin="round"]').node();
+    test.true(
+      contourG != null,
+      "Scatter should have contour showing the density of points after selecting show contour"
+    );
+    if (test._ok) holder.remove();
+    test.end();
+  }
+});
+(0, import_tape.default)("dynamic scatter of 2-gene expression", function(test) {
+  const holder = getHolder();
+  runpp({
+    holder,
+    state: state2geneexp,
+    sampleScatter: { callbacks: { "postRender.test": runTests } }
+  });
+  async function runTests(scatter) {
+    scatter.on("postRender.test", null);
+    const chart = scatter.Inner.model.charts[0];
+    test.true(scatter.Inner.settings.showAxes, "Dynamic scatter should have axes");
+    if (test._ok) holder.remove();
+    test.end();
+  }
+});
+(0, import_tape.default)("dynamic scatter of 2-ssgsea", function(test) {
+  const holder = getHolder();
+  runpp({
+    holder,
+    state: state2ssgsea,
+    sampleScatter: { callbacks: { "postRender.test": runTests } }
+  });
+  async function runTests(scatter) {
+    scatter.on("postRender.test", null);
+    const chart = scatter.Inner.model.charts[0];
+    test.true(scatter.Inner.settings.showAxes, "Dynamic scatter should have axes");
+    if (test._ok) holder.remove();
+    test.end();
+  }
+});
+(0, import_tape.default)("dynamic scatter of 2-dnameth", function(test) {
+  const holder = getHolder();
+  runpp({
+    holder,
+    state: state2dnameth,
+    sampleScatter: { callbacks: { "postRender.test": runTests } }
+  });
+  async function runTests(scatter) {
+    scatter.on("postRender.test", null);
+    const chart = scatter.Inner.model.charts[0];
+    test.true(scatter.Inner.settings.showAxes, "Dynamic scatter should have axes");
+    if (test._ok) holder.remove();
+    test.end();
+  }
+});
+(0, import_tape.default)("Show tooltip for sample", function(test) {
+  test.timeoutAfter(8e3);
+  test.plan(2);
+  const holder = getHolder();
+  runpp({
+    holder,
+    //Fix for test failing because survival & summary sandboxs are not destroyed.
+    state,
+    sampleScatter: {
+      callbacks: {
+        "postRender.test": runTests
+      }
+    }
+  });
+  async function runTests(scatter) {
+    scatter.on("postRender.test", null);
+    const chart = scatter.Inner.model.charts[0];
+    const sample = groups[0].items[0];
+    scatter.Inner.vm.scatterTooltip.showSampleTooltip(sample, 100, 100, chart);
+    const tooltipDiv = scatter.Inner.view.dom.tooltip.d.node();
+    const tree = scatter.Inner.vm.scatterTooltip.tree;
+    const parentNode = tree.find((n) => n.id == "Acute lymphoblastic leukemia" && n.samples.length == 3);
+    test.true(parentNode != null, "Tooltip should have 3 samples for Acute lymphoblastic leukemia");
+    test.true(tooltipDiv != null, "Tooltip should be shown");
+    scatter.Inner.view.dom.tooltip.hide();
+    if (test._ok) holder.remove();
+    test.end();
+  }
+});
+(0, import_tape.default)("Test scale dot", function(test) {
+  test.timeoutAfter(8e3);
+  test.plan(2);
+  const holder = getHolder();
+  const state2 = {
+    plots: [
+      {
+        chartType: "sampleScatter",
+        scaleDotTW: { id: "agedx", q: { mode: "continuous" } },
+        name: "TermdbTest TSNE"
+      }
+    ]
+  };
+  runpp({
+    holder,
+    //Fix for test failing because survival & summary sandboxs are not destroyed.
+    state: state2,
+    sampleScatter: {
+      callbacks: {
+        "postRender.test": runTests
+      }
+    }
+  });
+  async function runTests(scatter) {
+    scatter.on("postRender.test", null);
+    const self = scatter.Inner;
+    const chart = scatter.Inner.model.charts[0];
+    const dots = self.view.dom.mainDiv.selectAll(".sjpcb-scatter-series > path").nodes();
+    const minSize = self.settings.minShapeSize * self.zoom / 3;
+    const maxSize = self.settings.maxShapeSize * self.zoom / 3;
+    test.true(
+      dots.find((dot) => dot.getAttribute("transform").includes(`scale(${minSize})`)) != null,
+      `Dots with the minimum size should be found`
+    );
+    test.true(
+      dots.find((dot) => dot.getAttribute("transform").includes(`scale(${maxSize})`)) != null,
+      `Dots with the maximum size should be found`
+    );
+    if (test._ok) holder.remove();
+    test.end();
+  }
+});
+(0, import_tape.default)("Test lasso menus options", function(test) {
+  test.timeoutAfter(8e3);
+  runpp({
+    state,
+    sampleScatter: {
+      callbacks: {
+        "postRender.test": runTests
+      }
+    }
+  });
+  async function runTests(scatter) {
+    scatter.on("postRender.test", null);
+    await triggerLassoMenu(scatter);
+    if (test._ok) scatter.Inner.app.destroy();
+    test.end();
+  }
+  async function triggerLassoMenu(scatter) {
+    const group = groups[0];
+    scatter.Inner.vm.scatterLasso.showLassoMenu(new PointerEvent("click"), group.items);
+    const groupsMenu = scatter.Inner.view.dom.tip.d.selectAll("div.sja_menuoption").nodes();
+    const options = ["List 2 samples", "Add to a group", "Add to a group and filter", "Open sample view"];
+    for (const [i, node] of Object.entries(groupsMenu)) {
+      const option = node.innerText;
+      test.equal(option, options[i], `Should display ${option} in the menu`);
+    }
+    scatter.Inner.vm.scatterLasso.showTable(group, 0, 0, false);
+    testSampleTable(scatter, group);
+    groupsMenu[1].click();
+    await sleep(1e3);
+    test.equal(scatter.Inner.state.groups.length, 1, `Should create a group in mass state`);
+    groupsMenu[2].click();
+    await sleep(1e3);
+    test.equal(scatter.Inner.state.groups.length, 2, `Should create another group in mass state`);
+    test.true(
+      scatter.Inner.state.termfilter?.filter?.lst[1]?.lst[0]?.tvs?.term.type == "samplelst",
+      `Should create a samplelst filter in mass state`
+    );
+  }
+  function testSampleTable(scatter, group) {
+    const samplesRendered = scatter.Inner.view.dom.tip.d.selectAll(".sjpp_row_wrapper > td:nth-child(3)").nodes();
+    const samples2Check = [];
+    for (const item of samplesRendered) {
+      samples2Check.push(item.innerHTML);
+    }
+    let foundSamples = 0;
+    for (const sampleData of group.items) {
+      if (samples2Check.some((d) => d == sampleData.sample)) ++foundSamples;
+      else test.fail(`Sample = ${sampleData.sample} is not displayed in sample table`);
+    }
+    test.equal(samples2Check.length, foundSamples, `Should render all samples for ${group.name}`);
+    scatter.Inner.view.dom.tip.hide();
+  }
+});
+(0, import_tape.default)("Invalid colorTW.id", async function(test) {
+  test.timeoutAfter(3e3);
+  const message = `Should display error for colorTW.id not found within dataset`;
+  const holder = getHolder();
+  const id = "Not real data";
+  try {
+    runpp({
+      holder,
+      state: {
+        plots: [
+          {
+            chartType: "sampleScatter",
+            colorTW: { id },
+            name: "TermdbTest TSNE"
+          }
+        ]
+      }
+    });
+    const errorbar = await detectGte({ elem: holder.node(), selector: ".sja_errorbar" });
+    test.equal(errorbar.length, 1, "Should display only one error message.");
+    test.ok(
+      errorbar[0].innerText.includes(`missing dictionary term for id=${id}`),
+      `Should display, "Error: no term found for ${id} [sampleScatter getPlotConfig()]".`
+    );
+  } catch (e) {
+    test.fail(message + ": " + e);
+  }
+  if (test._ok) holder.remove();
+  test.end();
+});
+(0, import_tape.default)("Invalid colorTW.term", async function(test) {
+  test.timeoutAfter(3e3);
+  const holder = getHolder();
+  const id = "Not real data";
+  try {
+    runpp({
+      holder,
+      state: {
+        plots: [
+          {
+            chartType: "sampleScatter",
+            colorTW: { term: { id } },
+            name: "TermdbTest TSNE"
+          }
+        ]
+      }
+    });
+    const errorbar = await detectGte({ elem: holder.node(), selector: ".sja_errorbar > div:nth-child(2)" });
+    const error = "Error: Error: Type is not defined [sampleScatter getPlotConfig()]";
+    test.true(errorbar[0].innerText.startsWith(error), `Should display, "${error}...".`);
+  } catch (e) {
+    test.fail(e);
+  }
+  if (test._ok) holder.remove();
+  test.end();
+});
+(0, import_tape.default)("Invalid plot name", async function(test) {
+  test.timeoutAfter(3e3);
+  const message = `Should display error for invalid plot name`;
+  const holder = getHolder();
+  try {
+    runpp({
+      holder,
+      state: {
+        plots: [
+          {
+            chartType: "sampleScatter",
+            colorTW: {
+              id: "diaggrp"
+            },
+            name: "Not real data"
+          }
+        ]
+      }
+    });
+    const errorbar = await detectGte({ elem: holder.node(), selector: ".sja_errorbar" });
+    test.equal(errorbar.length, 1, "Should display only one error message.");
+    test.ok(
+      errorbar[0].innerText.includes(`plot not found with plotName`),
+      'Should display, "Error: plot not found with plotName: Not real data".'
+    );
+  } catch (e) {
+    test.fail(message + ": " + e);
+  }
+  if (test._ok) holder.remove();
+  test.end();
+});
+(0, import_tape.default)("Test legend", function(test) {
+  test.timeoutAfter(6e3);
+  runpp({
+    state: structuredClone(state),
+    sampleScatter: {
+      callbacks: {
+        "postRender.test": runTests
+      }
+    }
+  });
+  async function runTests(scatter) {
+    scatter.on("postRender.test", null);
+    const samples = scatter.Inner.model.charts[0].data.samples;
+    const scatterDiv = scatter.Inner.model.charts[0].chartDiv;
+    await testHideCategory(scatter, samples);
+    await testChangeColor(scatter, samples);
+    if (test._ok) scatter.Inner.app.destroy();
+    test.end();
+  }
+  async function testHideCategory(scatter, samples) {
+    const key = "Acute lymphoblastic leukemia";
+    const expectedNum = samples.filter((s) => s.category === key).length;
+    const matched = await detectChildStyle({
+      elem: scatter.Inner.view.dom.mainDiv.node(),
+      selector: ".sjpcb-scatter-series > path",
+      style: {
+        fillOpacity: "0"
+      },
+      count: expectedNum,
+      trigger: () => {
+        const chart = scatter.Inner.model.charts[0];
+        scatter.Inner.vm.legendvm.legendInteractivity.hideCategory(scatter.Inner.config.colorTW, key, true);
+        scatter.Inner.app.dispatch({
+          type: "plot_edit",
+          id: scatter.Inner.id,
+          config: { colorTW: scatter.Inner.config.colorTW }
+        });
+      }
+      /* example of a custom matcher, instead of opts.style
+               matcher(mutations, observer) {
+                   const hidden = mutations.filter(m => m.target.__data__.category == key && m.target.style.fillOpacity == '0')
+                   if (hidden.length >= expectedNum) return hidden.map(d => d.target)
+               }*/
+    });
+    test.equal(
+      matched.filter((t) => t.__data__.category == key).length,
+      expectedNum,
+      `Should remove all samples with category = ${key}`
+    );
+  }
+  async function testChangeColor(scatter, samples) {
+    const key = "Wilms tumor";
+    const color = "blue";
+    const expectedColor = rgb(color).toString();
+    const expectedNum = samples.filter((s) => s.category === key).length;
+    const targets = await detectChildAttr({
+      elem: scatter.Inner.view.dom.mainDiv.node(),
+      selector: ".sjpcb-scatter-series > path",
+      observe: {
+        attributeFilter: ["fill"]
+      },
+      /* example of opts.attr, instead of opts.matcher()
+               attr: {
+                   // key is name of attribute, value can be a string, number, or function
+                   fill: value => {
+                       return d3color.rgb(value).toString() === expectedColor
+                   }
+               },*/
+      count: expectedNum,
+      trigger: async () => {
+        scatter.Inner.vm.legendvm.legendInteractivity.changeColor(key, color);
+      },
+      // example of a custom matcher, instead of opts.attr{}
+      matcher(mutations) {
+        const targets2 = mutations.filter((m) => rgb(m.target.getAttribute("fill")) == expectedColor);
+        if (targets2.length >= expectedNum) return targets2.map((d) => d.target);
+      }
+    });
+    test.equal(targets.length, 2, `Should change the color of the category = ${key} to blue`);
+  }
+});
+(0, import_tape.default)("Render color groups", function(test) {
+  test.timeoutAfter(3e3);
+  runpp({
+    state: {
+      plots: [
+        {
+          chartType: "sampleScatter",
+          colorTW: {
+            id: "genetic_race",
+            q: {
+              customset: {
+                groups: [
+                  {
+                    name: "non-Asian Ancestry",
+                    type: "values",
+                    values: [
+                      { key: "European Ancestry", label: "European Ancestry" },
+                      { key: "African Ancestry", label: "African Ancestry" },
+                      { key: "Multi-Ancestry-Admixed", label: "Multi-Ancestry-Admixed" }
+                    ]
+                  },
+                  {
+                    name: "Asian Ancestry",
+                    type: "values",
+                    values: [{ key: "Asian Ancestry", label: "Asian Ancestry" }]
+                  }
+                ]
+              }
+            }
+          },
+          name: "TermdbTest TSNE"
+        }
+      ]
+    },
+    sampleScatter: {
+      callbacks: { "postRender.test": runTests }
+    }
+  });
+  async function runTests(scatter) {
+    scatter.on("postRender.test", null);
+    await testColorLegend(scatter);
+    await changeColorGroups(scatter);
+    await testColorLegend(scatter);
+    if (test._ok) scatter.Inner.app.destroy();
+    test.end();
+  }
+  async function testColorLegend(scatter) {
+    const legendLabels = await detectGte({
+      elem: scatter.Inner.model.charts[0].chartDiv.node(),
+      selector: 'text[name="sjpp-scatter-legend-label"]'
+    });
+    const groups2 = [];
+    for (const group of legendLabels) {
+      const label = group.innerHTML.split(",");
+      groups2.push({
+        label: label[0],
+        samples: label[1].match(/[\d\.]+/g)
+      });
+    }
+    test.equal(
+      scatter.Inner.model.charts[0].colorLegend.size,
+      groups2.length + 1,
+      `Legend categories (# = ${groups2.length + 1}) should equal size of colorLegend (# = ${scatter.Inner.model.charts[0].colorLegend.size}) `
+    );
+    compareData2DOMLegend(scatter, groups2);
+  }
+  function compareData2DOMLegend(scatter, groups2) {
+    for (const group of groups2) {
+      const mapLeg = scatter.Inner.model.charts[0].colorLegend.get(group.label);
+      test.ok(mapLeg, `Should display group custom label = ${group.label} in legend`);
+      test.equal(
+        `${mapLeg.sampleCount}`,
+        group.samples[0],
+        `Should show matching n = ${group.samples[0]} for ${group.label}`
+      );
+    }
+  }
+  async function changeColorGroups(scatter) {
+    scatter.Inner.config.colorTW.q.customset = {
+      groups: [
+        {
+          name: "European Ancestryy",
+          type: "values",
+          values: [{ key: "European Ancestry", label: "European Ancestry" }]
+        },
+        {
+          name: "non-European Ancestry",
+          type: "values",
+          values: [
+            { key: "Asian Ancestry", label: "Asian Ancestry" },
+            { key: "African Ancestry", label: "African Ancestry" },
+            { key: "Multi-Ancestry-Admixed", label: "Multi-Ancestry-Admixed" }
+          ]
+        }
+      ]
+    };
+    await scatter.Inner.app.dispatch({
+      type: "plot_edit",
+      id: scatter.Inner.id,
+      config: scatter.Inner.config
+    });
+  }
+});
+(0, import_tape.default)("Change symbol and reference size from menu", function(test) {
+  test.timeoutAfter(1e4);
+  runpp({
+    state: structuredClone(open_state),
+    sampleScatter: {
+      callbacks: { "postRender.test": runTests }
+    }
+  });
+  const testSymSize = 300;
+  const testRefSize = 1;
+  async function runTests(scatter) {
+    rideInit({ arg: scatter, bus: scatter, eventType: "postRender.test" }).use(changeSymbolInput).to(testSymbolSize, { wait: 100 }).use(changeRefInput, { wait: 100 }).to(testRefDotSize, { wait: 300 }).done(test);
+  }
+  function changeSymbolInput(scatter) {
+    const sizeInput = scatter.Inner.view.dom.controlsHolder.selectAll("input").nodes().find((e) => e.value == scatter.Inner.settings.size);
+    sizeInput.value = testSymSize;
+    sizeInput.dispatchEvent(new KeyboardEvent("keyup", { key: "Enter" }));
+  }
+  function testSymbolSize(scatter) {
+    test.equal(scatter.Inner.settings.size, testSymSize, `Should change symbol dot size to test value = ${testSymSize}`);
+  }
+  function changeRefInput(scatter) {
+    const refInput = scatter.Inner.view.dom.controlsHolder.selectAll("input").nodes().find((e) => e.value == scatter.Inner.settings.refSize);
+    refInput.value = testRefSize;
+    refInput.dispatchEvent(new KeyboardEvent("keyup", { key: "Enter" }));
+  }
+  function testRefDotSize(scatter) {
+    test.equal(
+      scatter.Inner.settings.refSize,
+      testRefSize,
+      `Should change reference dot size to test value = ${testRefSize}`
+    );
+  }
+});
+(0, import_tape.default)("Change chart width and height from menu", function(test) {
+  test.timeoutAfter(1e3);
+  runpp({
+    state: structuredClone(open_state),
+    sampleScatter: {
+      callbacks: { "postRender.test": runTests }
+    }
+  });
+  const testWidth = 550;
+  const testHeight = 550;
+  async function runTests(scatter) {
+    scatter.on("postRender.test", null);
+    await testChartSizeChange(scatter);
+    if (test._ok) scatter.Inner.app.destroy();
+    test.end();
+  }
+  async function testChartSizeChange(scatter) {
+    const widthInput = scatter.Inner.view.dom.controlsHolder.selectAll("input").nodes().find((e) => e.value == scatter.Inner.settings.svgw);
+    widthInput.value = testWidth;
+    const heightInput = scatter.Inner.view.dom.controlsHolder.selectAll("input").nodes().find((e) => e.value == scatter.Inner.settings.svgh);
+    heightInput.value = testHeight;
+    await detectAttr({
+      target: scatter.Inner.view.dom.mainDiv.select("svg").node(),
+      observe: {
+        attributeFilter: ["height", "width"]
+      },
+      // count: 1,
+      trigger() {
+        widthInput.dispatchEvent(new Event("change"));
+        heightInput.dispatchEvent(new Event("change"));
+      }
+      // matcher(mutations){
+      // 	let foundH, foundW = 0
+      // 	for (const mut of mutations) {
+      // 		if (mut.type == 'width') ++foundW
+      // 		if (mut.type == 'height') ++foundH
+      // 	}
+      // }
+    });
+    test.equal(
+      scatter.Inner.settings.svgw,
+      testWidth,
+      `Chart width = ${scatter.Inner.settings.svgw} should be equal to test width = ${testWidth}`
+    );
+    test.equal(
+      scatter.Inner.settings.svgh,
+      testHeight,
+      `Chart height = ${scatter.Inner.settings.svgh} should be equal to test height = ${testHeight}`
+    );
+  }
+});
+(0, import_tape.default)("Check/uncheck Show axes from menu", function(test) {
+  test.timeoutAfter(4e3);
+  runpp({
+    state: structuredClone(open_state),
+    sampleScatter: {
+      callbacks: { "postRender.test": runTests }
+    }
+  });
+  async function runTests(scatter) {
+    scatter.on("postRender.test", null);
+    await showAxes(scatter, true);
+    await showAxes(scatter, false);
+    if (test._ok) scatter.Inner.app.destroy();
+    test.end();
+  }
+  async function showAxes(scatter, isvisible) {
+    const opacity = isvisible ? 1 : 0;
+    const axesDiv = await detectStyle({
+      target: scatter.Inner.view.dom.mainDiv.node().querySelector(".sjpcb-scatter-axis"),
+      style: {
+        opacity: `${opacity}`
+      },
+      trigger() {
+        const axesCheckbox = scatter.Inner.view.dom.controlsHolder.select('input[data-testid="showAxes"]');
+        axesCheckbox.property("checked", isvisible);
+        axesCheckbox.node().dispatchEvent(new Event("change"));
+      }
+    });
+    const axesStyle = getComputedStyle(axesDiv[0]);
+    test.equal(axesStyle.opacity, `${opacity}`, `Should ${isvisible ? "show" : "hide"} axes`);
+  }
+});
+(0, import_tape.default)("Click zoom in, zoom out, and reset buttons", function(test) {
+  test.timeoutAfter(1e4);
+  runpp({
+    state: structuredClone(state),
+    sampleScatter: {
+      callbacks: {
+        "postRender.test": runTests
+      }
+    }
+  });
+  async function runTests(scatter) {
+    scatter.on("postRender.test", null);
+    await testZoomIn(scatter);
+    await testReset(scatter);
+    await testZoomOut(scatter);
+    if (test._ok) scatter.Inner.app.destroy();
+    test.end();
+  }
+  async function testZoomIn(scatter) {
+    const zoomin_bt = scatter.Inner.view.dom.toolsDiv.node().querySelector('div[name="sjpp-zoom-in-btn"]');
+    const m = await detectTransform(scatter, zoomin_bt, 1.2);
+    test.ok(m != null, `Plot should zoom in`);
+  }
+  async function testReset(scatter) {
+    const reset_bt = scatter.Inner.view.dom.toolsDiv.node().querySelector('div[name="sjpp-reset-btn"]');
+    const m = await detectTransform(scatter, reset_bt, 1);
+    test.ok(m != null, `Plot should reset`);
+  }
+  async function testZoomOut(scatter) {
+    const zoomout_bt = scatter.Inner.view.dom.toolsDiv.node().querySelector('div[name="sjpp-zoom-out-btn"]');
+    const m = await detectTransform(scatter, zoomout_bt, 0.8);
+    test.ok(m != null, `Plot should zoom out`);
+  }
+  async function detectTransform(scatter, btn, scale) {
+    const target = await detectAttr({
+      target: scatter.Inner.view.dom.mainDiv.node().querySelector(".sjpcb-scatter-series"),
+      observe: {
+        subtree: true,
+        characterData: true,
+        attributeFilter: ["transform"]
+      },
+      count: 1,
+      trigger() {
+        btn.click();
+      },
+      matcher(mutations) {
+        for (const m of mutations) {
+          if (m.attributeName == "transform" && m.target.attributes[1].value.includes(`scale(${scale})`)) return m;
+        }
+      }
+    });
+    return target;
+  }
+});
+(0, import_tape.default)("colorTW=geneVariant with no groupsetting", function(test) {
+  test.timeoutAfter(6e3);
+  runpp({
+    state: {
+      plots: [
+        {
+          chartType: "sampleScatter",
+          name: "TermdbTest TSNE",
+          colorTW: { term: { gene: "TP53", name: "TP53", type: "geneVariant" } }
+        }
+      ]
+    },
+    sampleScatter: { callbacks: { "postRender.test": runTests } }
+  });
+  async function runTests(scatter) {
+    const dots = scatter.Inner.view.dom.mainDiv.selectAll(".sjpcb-scatter-series > path").nodes();
+    test.true(
+      dots.find((dot) => dot.getAttribute("fill") == mclass["M"].color),
+      "At least a sample with MISSENSE color was expected"
+    );
+    if (test._ok) scatter.Inner.app.destroy();
+    test.end();
+  }
+});
+(0, import_tape.default)("colorTW=geneVariant with groupsetting", function(test) {
+  test.timeoutAfter(6e3);
+  runpp({
+    state: {
+      plots: [
+        {
+          chartType: "sampleScatter",
+          name: "TermdbTest TSNE",
+          colorTW: getGeneVariantTw()
+        }
+      ]
+    },
+    sampleScatter: { callbacks: { "postRender.test": runTests } }
+  });
+  async function runTests(scatter) {
+    const dots = scatter.Inner.view.dom.mainDiv.selectAll(".sjpcb-scatter-series > path").nodes();
+    const lab = "TP53 SNV/indel Mutated (somatic)";
+    test.true(
+      dots.find((d) => d.__data__.category == lab),
+      `A dot with category=${lab}`
+    );
+    if (test._ok) scatter.Inner.app.destroy();
+    test.end();
+  }
+});
+(0, import_tape.default)("colorTW=geneVariant with gene list", function(test) {
+  test.timeoutAfter(6e3);
+  runpp({
+    state: {
+      plots: [
+        {
+          chartType: "sampleScatter",
+          name: "TermdbTest TSNE",
+          colorTW: getGenesetMutTw()
+        }
+      ]
+    },
+    sampleScatter: { callbacks: { "postRender.test": runTests } }
+  });
+  async function runTests(scatter) {
+    const dots = scatter.Inner.view.dom.mainDiv.selectAll(".sjpcb-scatter-series > path").nodes();
+    const lab = "TP53, KRAS, AKT1, BCR SNV/indel Mutated (somatic)";
+    test.true(
+      dots.find((d) => d.__data__.category == lab),
+      `A dot with category=${lab}`
+    );
+    if (test._ok) scatter.Inner.app.destroy();
+    test.end();
+  }
+});
+(0, import_tape.default)("colorTW=ssgsea", function(test) {
+  test.timeoutAfter(6e3);
+  runpp({
+    state: {
+      plots: [
+        {
+          chartType: "sampleScatter",
+          name: "TermdbTest TSNE",
+          colorTW: getSsgseaTw()
+        }
+      ]
+    },
+    sampleScatter: { callbacks: { "postRender.test": runTests } }
+  });
+  async function runTests(scatter) {
+    const dots = scatter.Inner.view.dom.mainDiv.selectAll(".sjpcb-scatter-series > path").nodes();
+    test.true(
+      dots.find((d) => Number.isFinite(d.__data__.category)),
+      `A dot with category=number`
+    );
+    if (test._ok) scatter.Inner.app.destroy();
+    test.end();
+  }
+});
+(0, import_tape.default)("singlecell map", function(test) {
+  test.timeoutAfter(6e3);
+  runpp({
+    state: {
+      plots: [
+        {
+          chartType: "sampleScatter",
+          colorTW: getScctTw(),
+          singleCellPlot: { name: "scRNA", sample: { sID: "1_patient" } }
+        }
+      ]
+    },
+    sampleScatter: { callbacks: { "postRender.test": runTests } }
+  });
+  async function runTests(scatter) {
+    const dots = scatter.Inner.view.dom.mainDiv.selectAll(".sjpcb-scatter-series > path").nodes();
+    test.true(dots.length, "some dots are loaded from singlecell map");
+    if (test._ok) scatter.Inner.app.destroy();
+    test.end();
+  }
+});
+(0, import_tape.default)("singlecell geneexp", function(test) {
+  runpp({
+    state: state2scgeneexp,
+    sampleScatter: { callbacks: { "postRender.test": runTests } }
+  });
+  async function runTests(scatter) {
+    const dots = scatter.Inner.view.dom.mainDiv.selectAll(".sjpcb-scatter-series > path").nodes();
+    test.true(dots.length, "some dots are loaded from singlecell map");
+    if (test._ok) scatter.Inner.app.destroy();
+    test.end();
+  }
+});
+(0, import_tape.default)("Disco plot and lollipop", (test) => {
+  test.timeoutAfter(2e3);
+  const holder = getHolder();
+  runpp({
+    holder,
+    state: state2ssgsea,
+    sampleScatter: { callbacks: { "postRender.test": runTests } }
+  });
+  async function runTests(scatter) {
+    scatter.on("postRender.test", null);
+    const sampleWithMutDataFile = scatter.Inner.dom.mainDiv.select(".sjpcb-scatter-series").selectAll("path").filter((d) => d.sample === "3416").node();
+    const box = sampleWithMutDataFile.getBoundingClientRect();
+    sampleWithMutDataFile.dispatchEvent(
+      new MouseEvent("click", {
+        bubbles: true,
+        clientX: box.x + box.width / 2,
+        clientY: box.y + box.height / 2
+      })
+    );
+    const chordTexts = await detectGte({
+      elem: holder.node(),
+      selector: ".chord-text",
+      count: 1,
+      trigger: () => {
+        scatter.Inner.dom.tooltip.d.selectAll("button").filter(function() {
+          return this.innerHTML == "Disco";
+        }).node().click();
+      }
+    });
+    const label = [...chordTexts].find((c) => c.__data__?.text === "TP53");
+    if (!label) {
+      test.failt("must have a TP53 gene label");
+    } else {
+      const trackLabelsG = await detectGte({
+        elem: holder.node(),
+        selector: '[data-testid="sja_sample_menu_opener"]',
+        count: 2,
+        trigger: () => {
+          label.dispatchEvent(new MouseEvent("click"));
+        }
+      });
+      await sleep(500);
+      const trackLabels = [...trackLabelsG[0].querySelectorAll("text")];
+      test.equal(
+        trackLabels.filter((t) => t.innerHTML.includes("unknown data source")).length,
+        0,
+        "must not have an error after clicking a Disco plot gene label to launch a genome browser track"
+      );
+      if (test._ok) holder.remove();
+      test.end();
+    }
+  }
+});
+//# sourceMappingURL=scatter.integration.spec-6KRDNHHH.js.map