@inflexa-ai/harness 0.1.1
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/LICENSE +202 -0
- package/NOTICE +5 -0
- package/README.md +58 -0
- package/dist/agents/conversation-agent.d.ts +105 -0
- package/dist/agents/conversation-agent.js +140 -0
- package/dist/agents/report-builder.d.ts +32 -0
- package/dist/agents/report-builder.js +31 -0
- package/dist/agents/sandbox/__fixtures__/deps.d.ts +23 -0
- package/dist/agents/sandbox/__fixtures__/deps.js +96 -0
- package/dist/agents/sandbox/bulk-transcriptomics-agent.d.ts +8 -0
- package/dist/agents/sandbox/bulk-transcriptomics-agent.js +22 -0
- package/dist/agents/sandbox/cheminformatics-agent.d.ts +9 -0
- package/dist/agents/sandbox/cheminformatics-agent.js +62 -0
- package/dist/agents/sandbox/chromatin-agent.d.ts +8 -0
- package/dist/agents/sandbox/chromatin-agent.js +24 -0
- package/dist/agents/sandbox/data-profiler.d.ts +10 -0
- package/dist/agents/sandbox/data-profiler.js +24 -0
- package/dist/agents/sandbox/dna-methylation-agent.d.ts +8 -0
- package/dist/agents/sandbox/dna-methylation-agent.js +24 -0
- package/dist/agents/sandbox/drug-repurposing-agent.d.ts +8 -0
- package/dist/agents/sandbox/drug-repurposing-agent.js +54 -0
- package/dist/agents/sandbox/enrichment-agent.d.ts +8 -0
- package/dist/agents/sandbox/enrichment-agent.js +24 -0
- package/dist/agents/sandbox/ephemeral-executor.d.ts +9 -0
- package/dist/agents/sandbox/ephemeral-executor.js +29 -0
- package/dist/agents/sandbox/genomic-variant-agent.d.ts +8 -0
- package/dist/agents/sandbox/genomic-variant-agent.js +27 -0
- package/dist/agents/sandbox/immune-profiling-agent.d.ts +8 -0
- package/dist/agents/sandbox/immune-profiling-agent.js +43 -0
- package/dist/agents/sandbox/index.d.ts +31 -0
- package/dist/agents/sandbox/index.js +96 -0
- package/dist/agents/sandbox/metabolomics-agent.d.ts +8 -0
- package/dist/agents/sandbox/metabolomics-agent.js +15 -0
- package/dist/agents/sandbox/microbiome-agent.d.ts +8 -0
- package/dist/agents/sandbox/microbiome-agent.js +15 -0
- package/dist/agents/sandbox/multi-omics-integration-agent.d.ts +8 -0
- package/dist/agents/sandbox/multi-omics-integration-agent.js +33 -0
- package/dist/agents/sandbox/multimodal-sc-agent.d.ts +8 -0
- package/dist/agents/sandbox/multimodal-sc-agent.js +15 -0
- package/dist/agents/sandbox/network-agent.d.ts +8 -0
- package/dist/agents/sandbox/network-agent.js +25 -0
- package/dist/agents/sandbox/pkpd-clinical-response-agent.d.ts +8 -0
- package/dist/agents/sandbox/pkpd-clinical-response-agent.js +59 -0
- package/dist/agents/sandbox/proteomics-agent.d.ts +8 -0
- package/dist/agents/sandbox/proteomics-agent.js +15 -0
- package/dist/agents/sandbox/scientific-executor.d.ts +9 -0
- package/dist/agents/sandbox/scientific-executor.js +56 -0
- package/dist/agents/sandbox/shared.d.ts +100 -0
- package/dist/agents/sandbox/shared.js +195 -0
- package/dist/agents/sandbox/single-cell-agent.d.ts +8 -0
- package/dist/agents/sandbox/single-cell-agent.js +25 -0
- package/dist/agents/sandbox/spatial-omics-agent.d.ts +8 -0
- package/dist/agents/sandbox/spatial-omics-agent.js +15 -0
- package/dist/agents/sandbox/statistical-modeling-agent.d.ts +8 -0
- package/dist/agents/sandbox/statistical-modeling-agent.js +37 -0
- package/dist/agents/sandbox/translational-safety-agent.d.ts +8 -0
- package/dist/agents/sandbox/translational-safety-agent.js +59 -0
- package/dist/agents/sandbox/types.d.ts +34 -0
- package/dist/agents/sandbox/types.js +15 -0
- package/dist/agents/sandbox/validate-skills.d.ts +18 -0
- package/dist/agents/sandbox/validate-skills.js +40 -0
- package/dist/agents/sandbox-catalog.d.ts +33 -0
- package/dist/agents/sandbox-catalog.js +44 -0
- package/dist/agents/system-prompt.d.ts +25 -0
- package/dist/agents/system-prompt.js +23 -0
- package/dist/app/chat-turn.d.ts +35 -0
- package/dist/app/chat-turn.js +64 -0
- package/dist/app/data-profile-policy.d.ts +36 -0
- package/dist/app/data-profile-policy.js +37 -0
- package/dist/app/message-assembly.d.ts +65 -0
- package/dist/app/message-assembly.js +61 -0
- package/dist/app/synthesize-run.d.ts +57 -0
- package/dist/app/synthesize-run.js +103 -0
- package/dist/auth/local-auth-context.d.ts +19 -0
- package/dist/auth/local-auth-context.js +20 -0
- package/dist/auth/local-run-authorizer.d.ts +10 -0
- package/dist/auth/local-run-authorizer.js +23 -0
- package/dist/auth/types.d.ts +166 -0
- package/dist/auth/types.js +61 -0
- package/dist/billing/cached-resolver.d.ts +23 -0
- package/dist/billing/cached-resolver.js +61 -0
- package/dist/billing/noop-resolver.d.ts +6 -0
- package/dist/billing/noop-resolver.js +7 -0
- package/dist/billing/noop-run-charge.d.ts +6 -0
- package/dist/billing/noop-run-charge.js +10 -0
- package/dist/billing/resolver.d.ts +64 -0
- package/dist/billing/resolver.js +24 -0
- package/dist/billing/run-charge.d.ts +24 -0
- package/dist/billing/run-charge.js +9 -0
- package/dist/config/resource-limits.d.ts +76 -0
- package/dist/config/resource-limits.js +116 -0
- package/dist/contracts/analogy-report.d.ts +120 -0
- package/dist/contracts/analogy-report.js +50 -0
- package/dist/contracts/chat-events.d.ts +61 -0
- package/dist/contracts/chat-events.js +13 -0
- package/dist/contracts/chat-parts.d.ts +308 -0
- package/dist/contracts/chat-parts.js +13 -0
- package/dist/contracts/content-url.d.ts +49 -0
- package/dist/contracts/content-url.js +56 -0
- package/dist/contracts/index.d.ts +12 -0
- package/dist/contracts/index.js +5 -0
- package/dist/contracts/message.d.ts +36 -0
- package/dist/contracts/message.js +9 -0
- package/dist/contracts/part-registry.d.ts +18 -0
- package/dist/contracts/part-registry.js +28 -0
- package/dist/contracts/schemas/chat-events.d.ts +90 -0
- package/dist/contracts/schemas/chat-events.js +43 -0
- package/dist/contracts/schemas/chat-parts.d.ts +683 -0
- package/dist/contracts/schemas/chat-parts.js +295 -0
- package/dist/contracts/schemas/index.d.ts +2 -0
- package/dist/contracts/schemas/index.js +2 -0
- package/dist/contracts/target-assessment-row.d.ts +85 -0
- package/dist/contracts/target-assessment-row.js +37 -0
- package/dist/contracts/target-dossier.d.ts +16720 -0
- package/dist/contracts/target-dossier.js +1339 -0
- package/dist/data/clinical-benchmarks.json +108 -0
- package/dist/data/protein-family-modality.json +101 -0
- package/dist/data/safety-panel-schema.d.ts +64 -0
- package/dist/data/safety-panel-schema.js +34 -0
- package/dist/data/safety-panel.json +436 -0
- package/dist/execution/artifact-metadata.d.ts +74 -0
- package/dist/execution/artifact-metadata.js +203 -0
- package/dist/execution/artifact-record.d.ts +19 -0
- package/dist/execution/artifact-record.js +7 -0
- package/dist/execution/artifact-registration.d.ts +36 -0
- package/dist/execution/artifact-registration.js +61 -0
- package/dist/execution/artifact-registry.d.ts +82 -0
- package/dist/execution/artifact-registry.js +17 -0
- package/dist/execution/dbos-run-launcher.d.ts +7 -0
- package/dist/execution/dbos-run-launcher.js +38 -0
- package/dist/execution/ephemeral-runner.d.ts +81 -0
- package/dist/execution/ephemeral-runner.js +161 -0
- package/dist/execution/filesystem-artifact-registry.d.ts +57 -0
- package/dist/execution/filesystem-artifact-registry.js +92 -0
- package/dist/execution/noop-artifact-registry.d.ts +11 -0
- package/dist/execution/noop-artifact-registry.js +17 -0
- package/dist/execution/post-step-pipeline.d.ts +70 -0
- package/dist/execution/post-step-pipeline.js +207 -0
- package/dist/execution/post-step.d.ts +20 -0
- package/dist/execution/post-step.js +65 -0
- package/dist/execution/reconcile-manifest.d.ts +25 -0
- package/dist/execution/reconcile-manifest.js +132 -0
- package/dist/execution/report-render.d.ts +39 -0
- package/dist/execution/report-render.js +98 -0
- package/dist/execution/report-runner.d.ts +87 -0
- package/dist/execution/report-runner.js +227 -0
- package/dist/execution/run-authorizer.d.ts +43 -0
- package/dist/execution/run-authorizer.js +17 -0
- package/dist/execution/run-launcher.d.ts +36 -0
- package/dist/execution/run-launcher.js +15 -0
- package/dist/execution/run-synthesis.d.ts +107 -0
- package/dist/execution/run-synthesis.js +329 -0
- package/dist/execution/staged-input.d.ts +41 -0
- package/dist/execution/staged-input.js +15 -0
- package/dist/execution/step-summary-metrics.d.ts +10 -0
- package/dist/execution/step-summary-metrics.js +22 -0
- package/dist/execution/step-summary.d.ts +55 -0
- package/dist/execution/step-summary.js +106 -0
- package/dist/execution/topo-sort.d.ts +33 -0
- package/dist/execution/topo-sort.js +99 -0
- package/dist/index.d.ts +112 -0
- package/dist/index.js +157 -0
- package/dist/input-sanitization.d.ts +22 -0
- package/dist/input-sanitization.js +64 -0
- package/dist/lib/async-utils.d.ts +10 -0
- package/dist/lib/async-utils.js +24 -0
- package/dist/lib/chrome.d.ts +15 -0
- package/dist/lib/chrome.js +95 -0
- package/dist/lib/db-result.d.ts +93 -0
- package/dist/lib/db-result.js +197 -0
- package/dist/lib/fs-helpers.d.ts +74 -0
- package/dist/lib/fs-helpers.js +119 -0
- package/dist/lib/fs-result.d.ts +98 -0
- package/dist/lib/fs-result.js +137 -0
- package/dist/lib/host-concurrency.d.ts +16 -0
- package/dist/lib/host-concurrency.js +60 -0
- package/dist/lib/identifiers.d.ts +8 -0
- package/dist/lib/identifiers.js +10 -0
- package/dist/lib/metrics.d.ts +7 -0
- package/dist/lib/metrics.js +12 -0
- package/dist/lib/mime-detect.d.ts +17 -0
- package/dist/lib/mime-detect.js +29 -0
- package/dist/lib/otel.d.ts +30 -0
- package/dist/lib/otel.js +102 -0
- package/dist/lib/regulatory-corpus/fetch-fda-guidance.d.ts +35 -0
- package/dist/lib/regulatory-corpus/fetch-fda-guidance.js +107 -0
- package/dist/lib/regulatory-corpus/fetch-ich.d.ts +46 -0
- package/dist/lib/regulatory-corpus/fetch-ich.js +173 -0
- package/dist/lib/regulatory-corpus.d.ts +88 -0
- package/dist/lib/regulatory-corpus.js +141 -0
- package/dist/lib/result.d.ts +87 -0
- package/dist/lib/result.js +103 -0
- package/dist/lib/storage.d.ts +29 -0
- package/dist/lib/storage.js +37 -0
- package/dist/lib/streamed-download.d.ts +28 -0
- package/dist/lib/streamed-download.js +111 -0
- package/dist/lib/trace-context.d.ts +11 -0
- package/dist/lib/trace-context.js +49 -0
- package/dist/loop/__fixtures__/scripted-provider.d.ts +31 -0
- package/dist/loop/__fixtures__/scripted-provider.js +57 -0
- package/dist/loop/budget-exceeded.d.ts +22 -0
- package/dist/loop/budget-exceeded.js +41 -0
- package/dist/loop/metrics.d.ts +25 -0
- package/dist/loop/metrics.js +46 -0
- package/dist/loop/run-agent.d.ts +28 -0
- package/dist/loop/run-agent.js +204 -0
- package/dist/loop/run-step.d.ts +29 -0
- package/dist/loop/run-step.js +34 -0
- package/dist/loop/run-to-terminal.d.ts +46 -0
- package/dist/loop/run-to-terminal.js +51 -0
- package/dist/loop/types.d.ts +95 -0
- package/dist/loop/types.js +10 -0
- package/dist/memory/ai-sdk-message-storage.d.ts +20 -0
- package/dist/memory/ai-sdk-message-storage.js +114 -0
- package/dist/memory/card-builders.d.ts +114 -0
- package/dist/memory/card-builders.js +231 -0
- package/dist/memory/content-to-cortex.d.ts +42 -0
- package/dist/memory/content-to-cortex.js +85 -0
- package/dist/memory/count-tokens.d.ts +18 -0
- package/dist/memory/count-tokens.js +64 -0
- package/dist/memory/derive-thread-title.d.ts +14 -0
- package/dist/memory/derive-thread-title.js +26 -0
- package/dist/memory/message-backfill.d.ts +2 -0
- package/dist/memory/message-backfill.js +38 -0
- package/dist/memory/reconstruct-cards.d.ts +23 -0
- package/dist/memory/reconstruct-cards.js +64 -0
- package/dist/memory/thread-history.d.ts +80 -0
- package/dist/memory/thread-history.js +187 -0
- package/dist/memory/thread-store.d.ts +66 -0
- package/dist/memory/thread-store.js +88 -0
- package/dist/memory/working-memory.d.ts +135 -0
- package/dist/memory/working-memory.js +185 -0
- package/dist/prompts/SOUL.d.ts +17 -0
- package/dist/prompts/SOUL.js +173 -0
- package/dist/prompts/analogical-reasoner.d.ts +1 -0
- package/dist/prompts/analogical-reasoner.js +170 -0
- package/dist/prompts/conversation.d.ts +1 -0
- package/dist/prompts/conversation.js +697 -0
- package/dist/prompts/execute-analysis/step-summary.d.ts +1 -0
- package/dist/prompts/execute-analysis/step-summary.js +38 -0
- package/dist/prompts/literature-reviewer.d.ts +1 -0
- package/dist/prompts/literature-reviewer.js +107 -0
- package/dist/prompts/planner.d.ts +2 -0
- package/dist/prompts/planner.js +259 -0
- package/dist/prompts/report-builder.d.ts +1 -0
- package/dist/prompts/report-builder.js +127 -0
- package/dist/prompts/sandbox/bulk-transcriptomics-agent.d.ts +1 -0
- package/dist/prompts/sandbox/bulk-transcriptomics-agent.js +78 -0
- package/dist/prompts/sandbox/cheminformatics-agent.d.ts +1 -0
- package/dist/prompts/sandbox/cheminformatics-agent.js +224 -0
- package/dist/prompts/sandbox/chromatin-agent.d.ts +1 -0
- package/dist/prompts/sandbox/chromatin-agent.js +100 -0
- package/dist/prompts/sandbox/data-profiler.d.ts +1 -0
- package/dist/prompts/sandbox/data-profiler.js +291 -0
- package/dist/prompts/sandbox/dna-methylation-agent.d.ts +1 -0
- package/dist/prompts/sandbox/dna-methylation-agent.js +96 -0
- package/dist/prompts/sandbox/drug-repurposing-agent.d.ts +1 -0
- package/dist/prompts/sandbox/drug-repurposing-agent.js +144 -0
- package/dist/prompts/sandbox/enrichment-agent.d.ts +1 -0
- package/dist/prompts/sandbox/enrichment-agent.js +89 -0
- package/dist/prompts/sandbox/ephemeral-executor.d.ts +1 -0
- package/dist/prompts/sandbox/ephemeral-executor.js +66 -0
- package/dist/prompts/sandbox/genomic-variant-agent.d.ts +1 -0
- package/dist/prompts/sandbox/genomic-variant-agent.js +83 -0
- package/dist/prompts/sandbox/immune-profiling-agent.d.ts +1 -0
- package/dist/prompts/sandbox/immune-profiling-agent.js +101 -0
- package/dist/prompts/sandbox/metabolomics-agent.d.ts +1 -0
- package/dist/prompts/sandbox/metabolomics-agent.js +89 -0
- package/dist/prompts/sandbox/microbiome-agent.d.ts +1 -0
- package/dist/prompts/sandbox/microbiome-agent.js +109 -0
- package/dist/prompts/sandbox/multi-omics-integration-agent.d.ts +1 -0
- package/dist/prompts/sandbox/multi-omics-integration-agent.js +122 -0
- package/dist/prompts/sandbox/multimodal-sc-agent.d.ts +1 -0
- package/dist/prompts/sandbox/multimodal-sc-agent.js +90 -0
- package/dist/prompts/sandbox/network-agent.d.ts +1 -0
- package/dist/prompts/sandbox/network-agent.js +95 -0
- package/dist/prompts/sandbox/pkpd-clinical-response-agent.d.ts +1 -0
- package/dist/prompts/sandbox/pkpd-clinical-response-agent.js +71 -0
- package/dist/prompts/sandbox/proteomics-agent.d.ts +1 -0
- package/dist/prompts/sandbox/proteomics-agent.js +93 -0
- package/dist/prompts/sandbox/scientific-executor.d.ts +1 -0
- package/dist/prompts/sandbox/scientific-executor.js +68 -0
- package/dist/prompts/sandbox/single-cell-agent.d.ts +1 -0
- package/dist/prompts/sandbox/single-cell-agent.js +129 -0
- package/dist/prompts/sandbox/spatial-omics-agent.d.ts +1 -0
- package/dist/prompts/sandbox/spatial-omics-agent.js +94 -0
- package/dist/prompts/sandbox/statistical-modeling-agent.d.ts +1 -0
- package/dist/prompts/sandbox/statistical-modeling-agent.js +112 -0
- package/dist/prompts/sandbox/translational-safety-agent.d.ts +1 -0
- package/dist/prompts/sandbox/translational-safety-agent.js +105 -0
- package/dist/prompts/sandbox-standards.d.ts +18 -0
- package/dist/prompts/sandbox-standards.js +358 -0
- package/dist/prompts/synthesis-agent.d.ts +1 -0
- package/dist/prompts/synthesis-agent.js +289 -0
- package/dist/prompts/target-assessment/briefs/executive-recommendation.d.ts +1 -0
- package/dist/prompts/target-assessment/briefs/executive-recommendation.js +85 -0
- package/dist/prompts/target-assessment/briefs/index.d.ts +4 -0
- package/dist/prompts/target-assessment/briefs/index.js +4 -0
- package/dist/prompts/target-assessment/briefs/liability-bullets.d.ts +1 -0
- package/dist/prompts/target-assessment/briefs/liability-bullets.js +114 -0
- package/dist/prompts/target-assessment/briefs/target-organ-liabilities.d.ts +1 -0
- package/dist/prompts/target-assessment/briefs/target-organ-liabilities.js +29 -0
- package/dist/prompts/target-assessment/briefs/translational-commentary.d.ts +1 -0
- package/dist/prompts/target-assessment/briefs/translational-commentary.js +23 -0
- package/dist/prompts/target-assessment/drugs-in-class.d.ts +1 -0
- package/dist/prompts/target-assessment/drugs-in-class.js +29 -0
- package/dist/prompts/target-assessment/modulator-triage.d.ts +1 -0
- package/dist/prompts/target-assessment/modulator-triage.js +31 -0
- package/dist/prompts/target-assessment/off-target-annotator.d.ts +1 -0
- package/dist/prompts/target-assessment/off-target-annotator.js +28 -0
- package/dist/prompts/target-assessment/tox-voice/core.d.ts +1 -0
- package/dist/prompts/target-assessment/tox-voice/core.js +74 -0
- package/dist/prompts/target-assessment/tox-voice/critique.d.ts +7 -0
- package/dist/prompts/target-assessment/tox-voice/critique.js +109 -0
- package/dist/prompts/target-assessment/tox-voice/exemplars.d.ts +8 -0
- package/dist/prompts/target-assessment/tox-voice/exemplars.js +24 -0
- package/dist/prompts/target-assessment/tox-voice/index.d.ts +4 -0
- package/dist/prompts/target-assessment/tox-voice/index.js +4 -0
- package/dist/prompts/target-assessment/tox-voice/vocabulary.d.ts +15 -0
- package/dist/prompts/target-assessment/tox-voice/vocabulary.js +72 -0
- package/dist/provenance/collector.d.ts +148 -0
- package/dist/provenance/collector.js +296 -0
- package/dist/provenance/exec-frame.d.ts +36 -0
- package/dist/provenance/exec-frame.js +49 -0
- package/dist/provenance/types.d.ts +95 -0
- package/dist/provenance/types.js +64 -0
- package/dist/providers/__fixtures__/session.d.ts +16 -0
- package/dist/providers/__fixtures__/session.js +20 -0
- package/dist/providers/ai-sdk.d.ts +47 -0
- package/dist/providers/ai-sdk.js +142 -0
- package/dist/providers/anthropic.d.ts +22 -0
- package/dist/providers/anthropic.js +26 -0
- package/dist/providers/embedding.d.ts +32 -0
- package/dist/providers/embedding.js +42 -0
- package/dist/providers/errors.d.ts +80 -0
- package/dist/providers/errors.js +137 -0
- package/dist/providers/llm-capabilities.d.ts +33 -0
- package/dist/providers/llm-capabilities.js +58 -0
- package/dist/providers/streaming-chat.d.ts +23 -0
- package/dist/providers/streaming-chat.js +61 -0
- package/dist/providers/types.d.ts +59 -0
- package/dist/providers/types.js +8 -0
- package/dist/runtime/assemble.d.ts +68 -0
- package/dist/runtime/assemble.js +46 -0
- package/dist/runtime/boot.d.ts +73 -0
- package/dist/runtime/boot.js +65 -0
- package/dist/runtime/connection-budget.d.ts +48 -0
- package/dist/runtime/connection-budget.js +57 -0
- package/dist/runtime/dbos.d.ts +94 -0
- package/dist/runtime/dbos.js +160 -0
- package/dist/runtime/lifecycle.d.ts +12 -0
- package/dist/runtime/lifecycle.js +19 -0
- package/dist/runtime/pools.d.ts +25 -0
- package/dist/runtime/pools.js +30 -0
- package/dist/runtime/shutdown.d.ts +33 -0
- package/dist/runtime/shutdown.js +39 -0
- package/dist/sandbox/await-exec.d.ts +143 -0
- package/dist/sandbox/await-exec.js +406 -0
- package/dist/sandbox/client.d.ts +82 -0
- package/dist/sandbox/client.js +23 -0
- package/dist/sandbox/create-sandbox.d.ts +105 -0
- package/dist/sandbox/create-sandbox.js +132 -0
- package/dist/sandbox/deliver-exec-event.d.ts +25 -0
- package/dist/sandbox/deliver-exec-event.js +29 -0
- package/dist/sandbox/docker-client.d.ts +75 -0
- package/dist/sandbox/docker-client.js +315 -0
- package/dist/sandbox/estimate-data-profile-resources.d.ts +5 -0
- package/dist/sandbox/estimate-data-profile-resources.js +73 -0
- package/dist/sandbox/exec-id.d.ts +12 -0
- package/dist/sandbox/exec-id.js +20 -0
- package/dist/sandbox/execution-id.d.ts +30 -0
- package/dist/sandbox/execution-id.js +47 -0
- package/dist/sandbox/hmac.d.ts +54 -0
- package/dist/sandbox/hmac.js +67 -0
- package/dist/sandbox/identity.d.ts +15 -0
- package/dist/sandbox/identity.js +22 -0
- package/dist/sandbox/ignored-dirs.d.ts +7 -0
- package/dist/sandbox/ignored-dirs.js +7 -0
- package/dist/sandbox/k8s-client.d.ts +71 -0
- package/dist/sandbox/k8s-client.js +488 -0
- package/dist/sandbox/liveness.d.ts +60 -0
- package/dist/sandbox/liveness.js +82 -0
- package/dist/sandbox/mount-plan.d.ts +77 -0
- package/dist/sandbox/mount-plan.js +84 -0
- package/dist/sandbox/notification-sweep.d.ts +42 -0
- package/dist/sandbox/notification-sweep.js +74 -0
- package/dist/sandbox/reaper.d.ts +70 -0
- package/dist/sandbox/reaper.js +124 -0
- package/dist/sandbox/sandbox-error.d.ts +105 -0
- package/dist/sandbox/sandbox-error.js +92 -0
- package/dist/sandbox/sandbox-step-translate.d.ts +35 -0
- package/dist/sandbox/sandbox-step-translate.js +76 -0
- package/dist/sandbox/submit-exec.d.ts +33 -0
- package/dist/sandbox/submit-exec.js +68 -0
- package/dist/sandbox/types.d.ts +277 -0
- package/dist/sandbox/types.js +147 -0
- package/dist/sandbox/watchdog.d.ts +71 -0
- package/dist/sandbox/watchdog.js +150 -0
- package/dist/schemas/artifact-manifest.d.ts +34 -0
- package/dist/schemas/artifact-manifest.js +36 -0
- package/dist/schemas/data-profile-schemas.d.ts +92 -0
- package/dist/schemas/data-profile-schemas.js +89 -0
- package/dist/schemas/file-metadata.d.ts +51 -0
- package/dist/schemas/file-metadata.js +39 -0
- package/dist/schemas/plan-schemas.d.ts +110 -0
- package/dist/schemas/plan-schemas.js +50 -0
- package/dist/schemas/render-step-prompt.d.ts +32 -0
- package/dist/schemas/render-step-prompt.js +76 -0
- package/dist/schemas/run-synthesis.d.ts +148 -0
- package/dist/schemas/run-synthesis.js +87 -0
- package/dist/schemas/step-summary.d.ts +18 -0
- package/dist/schemas/step-summary.js +20 -0
- package/dist/schemas/validate-plan.d.ts +39 -0
- package/dist/schemas/validate-plan.js +120 -0
- package/dist/schemas/workflow-state.d.ts +314 -0
- package/dist/schemas/workflow-state.js +139 -0
- package/dist/state/active-sandboxes.d.ts +58 -0
- package/dist/state/active-sandboxes.js +100 -0
- package/dist/state/analyses-metrics.d.ts +21 -0
- package/dist/state/analyses-metrics.js +59 -0
- package/dist/state/analyses.d.ts +58 -0
- package/dist/state/analyses.js +132 -0
- package/dist/state/artifacts.d.ts +53 -0
- package/dist/state/artifacts.js +175 -0
- package/dist/state/data-profile.d.ts +176 -0
- package/dist/state/data-profile.js +284 -0
- package/dist/state/db.d.ts +10 -0
- package/dist/state/db.js +9 -0
- package/dist/state/index.d.ts +29 -0
- package/dist/state/index.js +20 -0
- package/dist/state/init.d.ts +14 -0
- package/dist/state/init.js +406 -0
- package/dist/state/plans.d.ts +56 -0
- package/dist/state/plans.js +117 -0
- package/dist/state/runs.d.ts +69 -0
- package/dist/state/runs.js +206 -0
- package/dist/state/schema.d.ts +150 -0
- package/dist/state/schema.js +100 -0
- package/dist/state/step-executions.d.ts +77 -0
- package/dist/state/step-executions.js +175 -0
- package/dist/state/target-assessments.d.ts +68 -0
- package/dist/state/target-assessments.js +222 -0
- package/dist/state/vector-store.d.ts +53 -0
- package/dist/state/vector-store.js +89 -0
- package/dist/tasks/data-profile.d.ts +171 -0
- package/dist/tasks/data-profile.js +461 -0
- package/dist/tasks/refresh-regulatory-corpus.d.ts +59 -0
- package/dist/tasks/refresh-regulatory-corpus.js +146 -0
- package/dist/tasks/regulatory-corpus-boot-refresh.d.ts +55 -0
- package/dist/tasks/regulatory-corpus-boot-refresh.js +149 -0
- package/dist/tools/__fixtures__/tool-context.d.ts +13 -0
- package/dist/tools/__fixtures__/tool-context.js +18 -0
- package/dist/tools/bio/check-safety-panel.d.ts +35 -0
- package/dist/tools/bio/check-safety-panel.js +76 -0
- package/dist/tools/bio/find-approval-precedent.d.ts +32 -0
- package/dist/tools/bio/find-approval-precedent.js +72 -0
- package/dist/tools/bio/get-article-details.d.ts +11 -0
- package/dist/tools/bio/get-article-details.js +20 -0
- package/dist/tools/bio/get-article-full-text.d.ts +19 -0
- package/dist/tools/bio/get-article-full-text.js +32 -0
- package/dist/tools/bio/get-bioactivity.d.ts +11 -0
- package/dist/tools/bio/get-bioactivity.js +23 -0
- package/dist/tools/bio/get-drug-info.d.ts +9 -0
- package/dist/tools/bio/get-drug-info.js +22 -0
- package/dist/tools/bio/get-impc-ko-profile.d.ts +9 -0
- package/dist/tools/bio/get-impc-ko-profile.js +20 -0
- package/dist/tools/bio/get-mechanism.d.ts +8 -0
- package/dist/tools/bio/get-mechanism.js +18 -0
- package/dist/tools/bio/get-pubchem-assays.d.ts +22 -0
- package/dist/tools/bio/get-pubchem-assays.js +107 -0
- package/dist/tools/bio/get-pubchem-cross-refs.d.ts +15 -0
- package/dist/tools/bio/get-pubchem-cross-refs.js +68 -0
- package/dist/tools/bio/get-target-safety.d.ts +18 -0
- package/dist/tools/bio/get-target-safety.js +26 -0
- package/dist/tools/bio/index.d.ts +41 -0
- package/dist/tools/bio/index.js +48 -0
- package/dist/tools/bio/keys.d.ts +31 -0
- package/dist/tools/bio/keys.js +30 -0
- package/dist/tools/bio/lookup-go-term.d.ts +31 -0
- package/dist/tools/bio/lookup-go-term.js +116 -0
- package/dist/tools/bio/search-bgee-expression.d.ts +10 -0
- package/dist/tools/bio/search-bgee-expression.js +24 -0
- package/dist/tools/bio/search-clinical-trials.d.ts +12 -0
- package/dist/tools/bio/search-clinical-trials.js +21 -0
- package/dist/tools/bio/search-clinvar.d.ts +13 -0
- package/dist/tools/bio/search-clinvar.js +28 -0
- package/dist/tools/bio/search-compounds.d.ts +22 -0
- package/dist/tools/bio/search-compounds.js +160 -0
- package/dist/tools/bio/search-ctx-chemical.d.ts +50 -0
- package/dist/tools/bio/search-ctx-chemical.js +130 -0
- package/dist/tools/bio/search-ctx-exposure.d.ts +55 -0
- package/dist/tools/bio/search-ctx-exposure.js +176 -0
- package/dist/tools/bio/search-ctx-hazard.d.ts +111 -0
- package/dist/tools/bio/search-ctx-hazard.js +178 -0
- package/dist/tools/bio/search-dgidb.d.ts +43 -0
- package/dist/tools/bio/search-dgidb.js +199 -0
- package/dist/tools/bio/search-disgenet.d.ts +30 -0
- package/dist/tools/bio/search-disgenet.js +84 -0
- package/dist/tools/bio/search-drugbank.d.ts +38 -0
- package/dist/tools/bio/search-drugbank.js +109 -0
- package/dist/tools/bio/search-faers.d.ts +11 -0
- package/dist/tools/bio/search-faers.js +23 -0
- package/dist/tools/bio/search-gene.d.ts +11 -0
- package/dist/tools/bio/search-gene.js +19 -0
- package/dist/tools/bio/search-geo-datasets.d.ts +20 -0
- package/dist/tools/bio/search-geo-datasets.js +86 -0
- package/dist/tools/bio/search-gwas-catalog.d.ts +33 -0
- package/dist/tools/bio/search-gwas-catalog.js +172 -0
- package/dist/tools/bio/search-interactions.d.ts +17 -0
- package/dist/tools/bio/search-interactions.js +31 -0
- package/dist/tools/bio/search-opentargets.d.ts +11 -0
- package/dist/tools/bio/search-opentargets.js +25 -0
- package/dist/tools/bio/search-pathway.d.ts +12 -0
- package/dist/tools/bio/search-pathway.js +32 -0
- package/dist/tools/bio/search-pharmgkb.d.ts +17 -0
- package/dist/tools/bio/search-pharmgkb.js +46 -0
- package/dist/tools/bio/search-pubchem-compound.d.ts +26 -0
- package/dist/tools/bio/search-pubchem-compound.js +110 -0
- package/dist/tools/bio/search-pubmed.d.ts +17 -0
- package/dist/tools/bio/search-pubmed.js +31 -0
- package/dist/tools/bio/search-targets.d.ts +9 -0
- package/dist/tools/bio/search-targets.js +20 -0
- package/dist/tools/bio/search-toxcast.d.ts +36 -0
- package/dist/tools/bio/search-toxcast.js +141 -0
- package/dist/tools/define-tool.d.ts +80 -0
- package/dist/tools/define-tool.js +48 -0
- package/dist/tools/display/index.d.ts +4 -0
- package/dist/tools/display/index.js +4 -0
- package/dist/tools/display/show-user.d.ts +33 -0
- package/dist/tools/display/show-user.js +67 -0
- package/dist/tools/execute-plan.d.ts +64 -0
- package/dist/tools/execute-plan.js +208 -0
- package/dist/tools/iterate-report.d.ts +172 -0
- package/dist/tools/iterate-report.js +521 -0
- package/dist/tools/lib/api-utils.d.ts +80 -0
- package/dist/tools/lib/api-utils.js +128 -0
- package/dist/tools/lib/bgee-client.d.ts +36 -0
- package/dist/tools/lib/bgee-client.js +150 -0
- package/dist/tools/lib/cbioportal-client.d.ts +34 -0
- package/dist/tools/lib/cbioportal-client.js +159 -0
- package/dist/tools/lib/chembl-client.d.ts +123 -0
- package/dist/tools/lib/chembl-client.js +458 -0
- package/dist/tools/lib/chembl-config.d.ts +5 -0
- package/dist/tools/lib/chembl-config.js +3 -0
- package/dist/tools/lib/clinical-benchmarks-client.d.ts +33 -0
- package/dist/tools/lib/clinical-benchmarks-client.js +54 -0
- package/dist/tools/lib/clinical-trials-client.d.ts +216 -0
- package/dist/tools/lib/clinical-trials-client.js +339 -0
- package/dist/tools/lib/clinicaltrials-config.d.ts +4 -0
- package/dist/tools/lib/clinicaltrials-config.js +2 -0
- package/dist/tools/lib/clinvar-client.d.ts +25 -0
- package/dist/tools/lib/clinvar-client.js +126 -0
- package/dist/tools/lib/disgenet-config.d.ts +2 -0
- package/dist/tools/lib/disgenet-config.js +11 -0
- package/dist/tools/lib/drugbank-config.d.ts +2 -0
- package/dist/tools/lib/drugbank-config.js +12 -0
- package/dist/tools/lib/ema-client.d.ts +45 -0
- package/dist/tools/lib/ema-client.js +127 -0
- package/dist/tools/lib/ema-config.d.ts +7 -0
- package/dist/tools/lib/ema-config.js +7 -0
- package/dist/tools/lib/ensembl-client.d.ts +27 -0
- package/dist/tools/lib/ensembl-client.js +82 -0
- package/dist/tools/lib/gwas-catalog-config.d.ts +4 -0
- package/dist/tools/lib/gwas-catalog-config.js +2 -0
- package/dist/tools/lib/identifier-resolver.d.ts +85 -0
- package/dist/tools/lib/identifier-resolver.js +333 -0
- package/dist/tools/lib/impc-client.d.ts +44 -0
- package/dist/tools/lib/impc-client.js +239 -0
- package/dist/tools/lib/iuphar-client.d.ts +75 -0
- package/dist/tools/lib/iuphar-client.js +230 -0
- package/dist/tools/lib/iuphar-config.d.ts +5 -0
- package/dist/tools/lib/iuphar-config.js +3 -0
- package/dist/tools/lib/ncbi-utils.d.ts +58 -0
- package/dist/tools/lib/ncbi-utils.js +286 -0
- package/dist/tools/lib/openfda-client.d.ts +53 -0
- package/dist/tools/lib/openfda-client.js +192 -0
- package/dist/tools/lib/openfda-config.d.ts +2 -0
- package/dist/tools/lib/openfda-config.js +2 -0
- package/dist/tools/lib/opentargets-client.d.ts +64 -0
- package/dist/tools/lib/opentargets-client.js +290 -0
- package/dist/tools/lib/opentargets-config.d.ts +5 -0
- package/dist/tools/lib/opentargets-config.js +5 -0
- package/dist/tools/lib/path-validation.d.ts +14 -0
- package/dist/tools/lib/path-validation.js +26 -0
- package/dist/tools/lib/pathway-client.d.ts +27 -0
- package/dist/tools/lib/pathway-client.js +149 -0
- package/dist/tools/lib/pharmgkb-config.d.ts +4 -0
- package/dist/tools/lib/pharmgkb-config.js +2 -0
- package/dist/tools/lib/preview-lock.d.ts +20 -0
- package/dist/tools/lib/preview-lock.js +35 -0
- package/dist/tools/lib/protein-family-modality.d.ts +16 -0
- package/dist/tools/lib/protein-family-modality.js +42 -0
- package/dist/tools/lib/protein-family-normalize.d.ts +12 -0
- package/dist/tools/lib/protein-family-normalize.js +46 -0
- package/dist/tools/lib/pubchem-client.d.ts +40 -0
- package/dist/tools/lib/pubchem-client.js +128 -0
- package/dist/tools/lib/pubchem-config.d.ts +5 -0
- package/dist/tools/lib/pubchem-config.js +3 -0
- package/dist/tools/lib/pubmed-client.d.ts +28 -0
- package/dist/tools/lib/pubmed-client.js +91 -0
- package/dist/tools/lib/report-preflight.d.ts +39 -0
- package/dist/tools/lib/report-preflight.js +283 -0
- package/dist/tools/lib/string-client.d.ts +33 -0
- package/dist/tools/lib/string-client.js +93 -0
- package/dist/tools/lib/toxcast-config.d.ts +2 -0
- package/dist/tools/lib/toxcast-config.js +11 -0
- package/dist/tools/lib/uniprot-client.d.ts +28 -0
- package/dist/tools/lib/uniprot-client.js +103 -0
- package/dist/tools/lib/uniprot-config.d.ts +5 -0
- package/dist/tools/lib/uniprot-config.js +3 -0
- package/dist/tools/memory/index.d.ts +4 -0
- package/dist/tools/memory/index.js +4 -0
- package/dist/tools/memory/update-working-memory.d.ts +25 -0
- package/dist/tools/memory/update-working-memory.js +112 -0
- package/dist/tools/registry.d.ts +15 -0
- package/dist/tools/registry.js +26 -0
- package/dist/tools/report/build-report.d.ts +13 -0
- package/dist/tools/report/build-report.js +26 -0
- package/dist/tools/report/index.d.ts +14 -0
- package/dist/tools/report/index.js +14 -0
- package/dist/tools/report/mint-preview-url.d.ts +26 -0
- package/dist/tools/report/mint-preview-url.js +44 -0
- package/dist/tools/report/preview-publisher.d.ts +37 -0
- package/dist/tools/report/preview-publisher.js +25 -0
- package/dist/tools/report/preview-snapshot.d.ts +26 -0
- package/dist/tools/report/preview-snapshot.js +121 -0
- package/dist/tools/report/submit-report.d.ts +25 -0
- package/dist/tools/report/submit-report.js +126 -0
- package/dist/tools/report/version-fs.d.ts +15 -0
- package/dist/tools/report/version-fs.js +154 -0
- package/dist/tools/research/context7-docs.d.ts +31 -0
- package/dist/tools/research/context7-docs.js +61 -0
- package/dist/tools/research/generate-analogy-report.d.ts +60 -0
- package/dist/tools/research/generate-analogy-report.js +288 -0
- package/dist/tools/research/generate-plan.d.ts +39 -0
- package/dist/tools/research/generate-plan.js +393 -0
- package/dist/tools/research/index.d.ts +15 -0
- package/dist/tools/research/index.js +15 -0
- package/dist/tools/research/inspect-run.d.ts +54 -0
- package/dist/tools/research/inspect-run.js +85 -0
- package/dist/tools/research/literature-reviewer.d.ts +29 -0
- package/dist/tools/research/literature-reviewer.js +84 -0
- package/dist/tools/research/search-arxiv.d.ts +32 -0
- package/dist/tools/research/search-arxiv.js +123 -0
- package/dist/tools/research/search-github-repos.d.ts +32 -0
- package/dist/tools/research/search-github-repos.js +86 -0
- package/dist/tools/research/search-semantic-scholar.d.ts +33 -0
- package/dist/tools/research/search-semantic-scholar.js +93 -0
- package/dist/tools/run-ephemeral.d.ts +33 -0
- package/dist/tools/run-ephemeral.js +65 -0
- package/dist/tools/sandbox/index.d.ts +7 -0
- package/dist/tools/sandbox/index.js +7 -0
- package/dist/tools/sandbox/list-available-packages.d.ts +7 -0
- package/dist/tools/sandbox/list-available-packages.js +27 -0
- package/dist/tools/sandbox/list-available-refs.d.ts +7 -0
- package/dist/tools/sandbox/list-available-refs.js +147 -0
- package/dist/tools/sandbox/report-blocker.d.ts +23 -0
- package/dist/tools/sandbox/report-blocker.js +39 -0
- package/dist/tools/sandbox/skills.d.ts +72 -0
- package/dist/tools/sandbox/skills.js +144 -0
- package/dist/tools/workspace/edit-file.d.ts +46 -0
- package/dist/tools/workspace/edit-file.js +100 -0
- package/dist/tools/workspace/execute-command.d.ts +80 -0
- package/dist/tools/workspace/execute-command.js +95 -0
- package/dist/tools/workspace/file-stat.d.ts +24 -0
- package/dist/tools/workspace/file-stat.js +37 -0
- package/dist/tools/workspace/grep.d.ts +57 -0
- package/dist/tools/workspace/grep.js +154 -0
- package/dist/tools/workspace/index.d.ts +26 -0
- package/dist/tools/workspace/index.js +27 -0
- package/dist/tools/workspace/list-files.d.ts +24 -0
- package/dist/tools/workspace/list-files.js +38 -0
- package/dist/tools/workspace/mutator.d.ts +83 -0
- package/dist/tools/workspace/mutator.js +81 -0
- package/dist/tools/workspace/read-file.d.ts +39 -0
- package/dist/tools/workspace/read-file.js +93 -0
- package/dist/tools/workspace/result-bounds.d.ts +42 -0
- package/dist/tools/workspace/result-bounds.js +50 -0
- package/dist/tools/workspace/run-exec.d.ts +32 -0
- package/dist/tools/workspace/run-exec.js +34 -0
- package/dist/tools/workspace/show-file.d.ts +37 -0
- package/dist/tools/workspace/show-file.js +54 -0
- package/dist/tools/workspace/show-plan.d.ts +23 -0
- package/dist/tools/workspace/show-plan.js +44 -0
- package/dist/tools/workspace/workspace-search.d.ts +25 -0
- package/dist/tools/workspace/workspace-search.js +78 -0
- package/dist/tools/workspace/write-file.d.ts +16 -0
- package/dist/tools/workspace/write-file.js +33 -0
- package/dist/workflows/execute-analysis-scheduler.d.ts +94 -0
- package/dist/workflows/execute-analysis-scheduler.js +186 -0
- package/dist/workflows/execute-analysis.d.ts +271 -0
- package/dist/workflows/execute-analysis.js +746 -0
- package/dist/workflows/execute-target-assessment.d.ts +101 -0
- package/dist/workflows/execute-target-assessment.js +528 -0
- package/dist/workflows/metrics.d.ts +37 -0
- package/dist/workflows/metrics.js +55 -0
- package/dist/workflows/plan/level.d.ts +12 -0
- package/dist/workflows/plan/level.js +12 -0
- package/dist/workflows/register-workflows.d.ts +51 -0
- package/dist/workflows/register-workflows.js +48 -0
- package/dist/workflows/resume-execute-analysis.d.ts +70 -0
- package/dist/workflows/resume-execute-analysis.js +80 -0
- package/dist/workflows/sandbox-step.d.ts +243 -0
- package/dist/workflows/sandbox-step.js +573 -0
- package/dist/workflows/target-assessment/assemblers/index.d.ts +5 -0
- package/dist/workflows/target-assessment/assemblers/index.js +4 -0
- package/dist/workflows/target-assessment/assemblers/literature.d.ts +299 -0
- package/dist/workflows/target-assessment/assemblers/literature.js +987 -0
- package/dist/workflows/target-assessment/assemblers/orchestrator.d.ts +109 -0
- package/dist/workflows/target-assessment/assemblers/orchestrator.js +835 -0
- package/dist/workflows/target-assessment/assemblers/safety.d.ts +352 -0
- package/dist/workflows/target-assessment/assemblers/safety.js +985 -0
- package/dist/workflows/target-assessment/assemblers/trials.d.ts +30 -0
- package/dist/workflows/target-assessment/assemblers/trials.js +75 -0
- package/dist/workflows/target-assessment/collectors/index.d.ts +105 -0
- package/dist/workflows/target-assessment/collectors/index.js +468 -0
- package/dist/workflows/target-assessment/correction-loop.d.ts +45 -0
- package/dist/workflows/target-assessment/correction-loop.js +62 -0
- package/dist/workflows/target-assessment/coverage.d.ts +81 -0
- package/dist/workflows/target-assessment/coverage.js +82 -0
- package/dist/workflows/target-assessment/decisions/index.d.ts +86 -0
- package/dist/workflows/target-assessment/decisions/index.js +127 -0
- package/dist/workflows/target-assessment/fanout/index.d.ts +31 -0
- package/dist/workflows/target-assessment/fanout/index.js +155 -0
- package/dist/workflows/target-assessment/lib/approval-precedents.d.ts +52 -0
- package/dist/workflows/target-assessment/lib/approval-precedents.js +119 -0
- package/dist/workflows/target-assessment/lib/citation-validator.d.ts +46 -0
- package/dist/workflows/target-assessment/lib/citation-validator.js +316 -0
- package/dist/workflows/target-assessment/lib/clinical-consequence-annotator.d.ts +62 -0
- package/dist/workflows/target-assessment/lib/clinical-consequence-annotator.js +172 -0
- package/dist/workflows/target-assessment/lib/clinical-evidence-attribution.d.ts +45 -0
- package/dist/workflows/target-assessment/lib/clinical-evidence-attribution.js +156 -0
- package/dist/workflows/target-assessment/lib/compute-derived.d.ts +19 -0
- package/dist/workflows/target-assessment/lib/compute-derived.js +252 -0
- package/dist/workflows/target-assessment/lib/compute-selectivity.d.ts +15 -0
- package/dist/workflows/target-assessment/lib/compute-selectivity.js +18 -0
- package/dist/workflows/target-assessment/lib/dedup-modulators.d.ts +37 -0
- package/dist/workflows/target-assessment/lib/dedup-modulators.js +157 -0
- package/dist/workflows/target-assessment/lib/evidence-conflict-detector.d.ts +17 -0
- package/dist/workflows/target-assessment/lib/evidence-conflict-detector.js +100 -0
- package/dist/workflows/target-assessment/lib/expression-constants.d.ts +21 -0
- package/dist/workflows/target-assessment/lib/expression-constants.js +21 -0
- package/dist/workflows/target-assessment/lib/family-complex-supplement.d.ts +21 -0
- package/dist/workflows/target-assessment/lib/family-complex-supplement.js +37 -0
- package/dist/workflows/target-assessment/lib/heterodimer-filter.d.ts +39 -0
- package/dist/workflows/target-assessment/lib/heterodimer-filter.js +54 -0
- package/dist/workflows/target-assessment/lib/intended-polypharm-filter.d.ts +4 -0
- package/dist/workflows/target-assessment/lib/intended-polypharm-filter.js +24 -0
- package/dist/workflows/target-assessment/lib/llm-step.d.ts +77 -0
- package/dist/workflows/target-assessment/lib/llm-step.js +99 -0
- package/dist/workflows/target-assessment/lib/meddra-organ-map.d.ts +30 -0
- package/dist/workflows/target-assessment/lib/meddra-organ-map.js +126 -0
- package/dist/workflows/target-assessment/lib/recommendation-quality-gates.d.ts +17 -0
- package/dist/workflows/target-assessment/lib/recommendation-quality-gates.js +99 -0
- package/dist/workflows/target-assessment/lib/recommendation-sanitizer.d.ts +2 -0
- package/dist/workflows/target-assessment/lib/recommendation-sanitizer.js +51 -0
- package/dist/workflows/target-assessment/lib/regulatory-actions.d.ts +26 -0
- package/dist/workflows/target-assessment/lib/regulatory-actions.js +147 -0
- package/dist/workflows/target-assessment/lib/structured-llm.d.ts +58 -0
- package/dist/workflows/target-assessment/lib/structured-llm.js +101 -0
- package/dist/workflows/target-assessment/lib/target-identity-filter.d.ts +60 -0
- package/dist/workflows/target-assessment/lib/target-identity-filter.js +86 -0
- package/dist/workflows/target-assessment/lib/therapeutic-programs.d.ts +20 -0
- package/dist/workflows/target-assessment/lib/therapeutic-programs.js +68 -0
- package/dist/workflows/target-assessment/metrics.d.ts +21 -0
- package/dist/workflows/target-assessment/metrics.js +42 -0
- package/dist/workflows/target-assessment/phase4-assemble.d.ts +1841 -0
- package/dist/workflows/target-assessment/phase4-assemble.js +39 -0
- package/dist/workflows/target-assessment/phase5-persist.d.ts +57 -0
- package/dist/workflows/target-assessment/phase5-persist.js +461 -0
- package/dist/workflows/target-assessment/progress.d.ts +38 -0
- package/dist/workflows/target-assessment/progress.js +76 -0
- package/dist/workflows/target-assessment/schemas.d.ts +931 -0
- package/dist/workflows/target-assessment/schemas.js +293 -0
- package/dist/workflows/target-assessment/steps/collectors/pathways.d.ts +15 -0
- package/dist/workflows/target-assessment/steps/collectors/pathways.js +58 -0
- package/dist/workflows/target-assessment/steps/fanout/aes-for-one-class-drug-step.d.ts +34 -0
- package/dist/workflows/target-assessment/steps/fanout/aes-for-one-class-drug-step.js +31 -0
- package/dist/workflows/target-assessment/steps/fanout/aes-for-one-trial-step.d.ts +57 -0
- package/dist/workflows/target-assessment/steps/fanout/aes-for-one-trial-step.js +54 -0
- package/dist/workflows/target-assessment/steps/fanout/faers-for-one-modulator-step.d.ts +35 -0
- package/dist/workflows/target-assessment/steps/fanout/faers-for-one-modulator-step.js +32 -0
- package/dist/workflows/target-assessment/steps/fanout/index.d.ts +14 -0
- package/dist/workflows/target-assessment/steps/fanout/index.js +10 -0
- package/dist/workflows/target-assessment/steps/fanout/polypharm-for-one-modulator-step.d.ts +28 -0
- package/dist/workflows/target-assessment/steps/fanout/polypharm-for-one-modulator-step.js +27 -0
- package/dist/workflows/target-assessment/steps/phase0-resolve.d.ts +71 -0
- package/dist/workflows/target-assessment/steps/phase0-resolve.js +21 -0
- package/dist/workflows/target-assessment/steps/phase1-aggregate.d.ts +1018 -0
- package/dist/workflows/target-assessment/steps/phase1-aggregate.js +25 -0
- package/dist/workflows/target-assessment/steps/phase2-aggregate.d.ts +696 -0
- package/dist/workflows/target-assessment/steps/phase2-aggregate.js +38 -0
- package/dist/workflows/target-assessment/steps/phase3-aggregate.d.ts +936 -0
- package/dist/workflows/target-assessment/steps/phase3-aggregate.js +22 -0
- package/dist/workflows/target-assessment/steps/synthesis/diagnostics.d.ts +34 -0
- package/dist/workflows/target-assessment/steps/synthesis/diagnostics.js +45 -0
- package/dist/workflows/target-assessment/sub-workflows/index.d.ts +15 -0
- package/dist/workflows/target-assessment/sub-workflows/index.js +11 -0
- package/dist/workflows/target-assessment/sub-workflows/per-class-drug-aes.d.ts +41 -0
- package/dist/workflows/target-assessment/sub-workflows/per-class-drug-aes.js +12 -0
- package/dist/workflows/target-assessment/sub-workflows/per-modulator-faers.d.ts +41 -0
- package/dist/workflows/target-assessment/sub-workflows/per-modulator-faers.js +12 -0
- package/dist/workflows/target-assessment/sub-workflows/per-modulator-polypharm.d.ts +36 -0
- package/dist/workflows/target-assessment/sub-workflows/per-modulator-polypharm.js +12 -0
- package/dist/workflows/target-assessment/sub-workflows/per-trial-aes.d.ts +66 -0
- package/dist/workflows/target-assessment/sub-workflows/per-trial-aes.js +12 -0
- package/dist/workflows/target-assessment/synthesis/index.d.ts +560 -0
- package/dist/workflows/target-assessment/synthesis/index.js +351 -0
- package/dist/workflows/target-assessment/synthesis-probes.d.ts +56 -0
- package/dist/workflows/target-assessment/synthesis-probes.js +320 -0
- package/dist/workspace/filesystem.d.ts +117 -0
- package/dist/workspace/filesystem.js +304 -0
- package/dist/workspace/mount-strategy.d.ts +50 -0
- package/dist/workspace/mount-strategy.js +67 -0
- package/dist/workspace/paths.d.ts +185 -0
- package/dist/workspace/paths.js +219 -0
- package/dist/workspace/provenance-collector.d.ts +34 -0
- package/dist/workspace/provenance-collector.js +16 -0
- package/dist/workspace/search-config.d.ts +23 -0
- package/dist/workspace/search-config.js +43 -0
- package/dist/workspace/workspace-paths.d.ts +26 -0
- package/dist/workspace/workspace-paths.js +31 -0
- package/package.json +101 -0
package/LICENSE
ADDED
|
@@ -0,0 +1,202 @@
|
|
|
1
|
+
|
|
2
|
+
Apache License
|
|
3
|
+
Version 2.0, January 2004
|
|
4
|
+
http://www.apache.org/licenses/
|
|
5
|
+
|
|
6
|
+
TERMS AND CONDITIONS FOR USE, REPRODUCTION, AND DISTRIBUTION
|
|
7
|
+
|
|
8
|
+
1. Definitions.
|
|
9
|
+
|
|
10
|
+
"License" shall mean the terms and conditions for use, reproduction,
|
|
11
|
+
and distribution as defined by Sections 1 through 9 of this document.
|
|
12
|
+
|
|
13
|
+
"Licensor" shall mean the copyright owner or entity authorized by
|
|
14
|
+
the copyright owner that is granting the License.
|
|
15
|
+
|
|
16
|
+
"Legal Entity" shall mean the union of the acting entity and all
|
|
17
|
+
other entities that control, are controlled by, or are under common
|
|
18
|
+
control with that entity. For the purposes of this definition,
|
|
19
|
+
"control" means (i) the power, direct or indirect, to cause the
|
|
20
|
+
direction or management of such entity, whether by contract or
|
|
21
|
+
otherwise, or (ii) ownership of fifty percent (50%) or more of the
|
|
22
|
+
outstanding shares, or (iii) beneficial ownership of such entity.
|
|
23
|
+
|
|
24
|
+
"You" (or "Your") shall mean an individual or Legal Entity
|
|
25
|
+
exercising permissions granted by this License.
|
|
26
|
+
|
|
27
|
+
"Source" form shall mean the preferred form for making modifications,
|
|
28
|
+
including but not limited to software source code, documentation
|
|
29
|
+
source, and configuration files.
|
|
30
|
+
|
|
31
|
+
"Object" form shall mean any form resulting from mechanical
|
|
32
|
+
transformation or translation of a Source form, including but
|
|
33
|
+
not limited to compiled object code, generated documentation,
|
|
34
|
+
and conversions to other media types.
|
|
35
|
+
|
|
36
|
+
"Work" shall mean the work of authorship, whether in Source or
|
|
37
|
+
Object form, made available under the License, as indicated by a
|
|
38
|
+
copyright notice that is included in or attached to the work
|
|
39
|
+
(an example is provided in the Appendix below).
|
|
40
|
+
|
|
41
|
+
"Derivative Works" shall mean any work, whether in Source or Object
|
|
42
|
+
form, that is based on (or derived from) the Work and for which the
|
|
43
|
+
editorial revisions, annotations, elaborations, or other modifications
|
|
44
|
+
represent, as a whole, an original work of authorship. For the purposes
|
|
45
|
+
of this License, Derivative Works shall not include works that remain
|
|
46
|
+
separable from, or merely link (or bind by name) to the interfaces of,
|
|
47
|
+
the Work and Derivative Works thereof.
|
|
48
|
+
|
|
49
|
+
"Contribution" shall mean any work of authorship, including
|
|
50
|
+
the original version of the Work and any modifications or additions
|
|
51
|
+
to that Work or Derivative Works thereof, that is intentionally
|
|
52
|
+
submitted to Licensor for inclusion in the Work by the copyright owner
|
|
53
|
+
or by an individual or Legal Entity authorized to submit on behalf of
|
|
54
|
+
the copyright owner. For the purposes of this definition, "submitted"
|
|
55
|
+
means any form of electronic, verbal, or written communication sent
|
|
56
|
+
to the Licensor or its representatives, including but not limited to
|
|
57
|
+
communication on electronic mailing lists, source code control systems,
|
|
58
|
+
and issue tracking systems that are managed by, or on behalf of, the
|
|
59
|
+
Licensor for the purpose of discussing and improving the Work, but
|
|
60
|
+
excluding communication that is conspicuously marked or otherwise
|
|
61
|
+
designated in writing by the copyright owner as "Not a Contribution."
|
|
62
|
+
|
|
63
|
+
"Contributor" shall mean Licensor and any individual or Legal Entity
|
|
64
|
+
on behalf of whom a Contribution has been received by Licensor and
|
|
65
|
+
subsequently incorporated within the Work.
|
|
66
|
+
|
|
67
|
+
2. Grant of Copyright License. Subject to the terms and conditions of
|
|
68
|
+
this License, each Contributor hereby grants to You a perpetual,
|
|
69
|
+
worldwide, non-exclusive, no-charge, royalty-free, irrevocable
|
|
70
|
+
copyright license to reproduce, prepare Derivative Works of,
|
|
71
|
+
publicly display, publicly perform, sublicense, and distribute the
|
|
72
|
+
Work and such Derivative Works in Source or Object form.
|
|
73
|
+
|
|
74
|
+
3. Grant of Patent License. Subject to the terms and conditions of
|
|
75
|
+
this License, each Contributor hereby grants to You a perpetual,
|
|
76
|
+
worldwide, non-exclusive, no-charge, royalty-free, irrevocable
|
|
77
|
+
(except as stated in this section) patent license to make, have made,
|
|
78
|
+
use, offer to sell, sell, import, and otherwise transfer the Work,
|
|
79
|
+
where such license applies only to those patent claims licensable
|
|
80
|
+
by such Contributor that are necessarily infringed by their
|
|
81
|
+
Contribution(s) alone or by combination of their Contribution(s)
|
|
82
|
+
with the Work to which such Contribution(s) was submitted. If You
|
|
83
|
+
institute patent litigation against any entity (including a
|
|
84
|
+
cross-claim or counterclaim in a lawsuit) alleging that the Work
|
|
85
|
+
or a Contribution incorporated within the Work constitutes direct
|
|
86
|
+
or contributory patent infringement, then any patent licenses
|
|
87
|
+
granted to You under this License for that Work shall terminate
|
|
88
|
+
as of the date such litigation is filed.
|
|
89
|
+
|
|
90
|
+
4. Redistribution. You may reproduce and distribute copies of the
|
|
91
|
+
Work or Derivative Works thereof in any medium, with or without
|
|
92
|
+
modifications, and in Source or Object form, provided that You
|
|
93
|
+
meet the following conditions:
|
|
94
|
+
|
|
95
|
+
(a) You must give any other recipients of the Work or
|
|
96
|
+
Derivative Works a copy of this License; and
|
|
97
|
+
|
|
98
|
+
(b) You must cause any modified files to carry prominent notices
|
|
99
|
+
stating that You changed the files; and
|
|
100
|
+
|
|
101
|
+
(c) You must retain, in the Source form of any Derivative Works
|
|
102
|
+
that You distribute, all copyright, patent, trademark, and
|
|
103
|
+
attribution notices from the Source form of the Work,
|
|
104
|
+
excluding those notices that do not pertain to any part of
|
|
105
|
+
the Derivative Works; and
|
|
106
|
+
|
|
107
|
+
(d) If the Work includes a "NOTICE" text file as part of its
|
|
108
|
+
distribution, then any Derivative Works that You distribute must
|
|
109
|
+
include a readable copy of the attribution notices contained
|
|
110
|
+
within such NOTICE file, excluding those notices that do not
|
|
111
|
+
pertain to any part of the Derivative Works, in at least one
|
|
112
|
+
of the following places: within a NOTICE text file distributed
|
|
113
|
+
as part of the Derivative Works; within the Source form or
|
|
114
|
+
documentation, if provided along with the Derivative Works; or,
|
|
115
|
+
within a display generated by the Derivative Works, if and
|
|
116
|
+
wherever such third-party notices normally appear. The contents
|
|
117
|
+
of the NOTICE file are for informational purposes only and
|
|
118
|
+
do not modify the License. You may add Your own attribution
|
|
119
|
+
notices within Derivative Works that You distribute, alongside
|
|
120
|
+
or as an addendum to the NOTICE text from the Work, provided
|
|
121
|
+
that such additional attribution notices cannot be construed
|
|
122
|
+
as modifying the License.
|
|
123
|
+
|
|
124
|
+
You may add Your own copyright statement to Your modifications and
|
|
125
|
+
may provide additional or different license terms and conditions
|
|
126
|
+
for use, reproduction, or distribution of Your modifications, or
|
|
127
|
+
for any such Derivative Works as a whole, provided Your use,
|
|
128
|
+
reproduction, and distribution of the Work otherwise complies with
|
|
129
|
+
the conditions stated in this License.
|
|
130
|
+
|
|
131
|
+
5. Submission of Contributions. Unless You explicitly state otherwise,
|
|
132
|
+
any Contribution intentionally submitted for inclusion in the Work
|
|
133
|
+
by You to the Licensor shall be under the terms and conditions of
|
|
134
|
+
this License, without any additional terms or conditions.
|
|
135
|
+
Notwithstanding the above, nothing herein shall supersede or modify
|
|
136
|
+
the terms of any separate license agreement you may have executed
|
|
137
|
+
with Licensor regarding such Contributions.
|
|
138
|
+
|
|
139
|
+
6. Trademarks. This License does not grant permission to use the trade
|
|
140
|
+
names, trademarks, service marks, or product names of the Licensor,
|
|
141
|
+
except as required for reasonable and customary use in describing the
|
|
142
|
+
origin of the Work and reproducing the content of the NOTICE file.
|
|
143
|
+
|
|
144
|
+
7. Disclaimer of Warranty. Unless required by applicable law or
|
|
145
|
+
agreed to in writing, Licensor provides the Work (and each
|
|
146
|
+
Contributor provides its Contributions) on an "AS IS" BASIS,
|
|
147
|
+
WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or
|
|
148
|
+
implied, including, without limitation, any warranties or conditions
|
|
149
|
+
of TITLE, NON-INFRINGEMENT, MERCHANTABILITY, or FITNESS FOR A
|
|
150
|
+
PARTICULAR PURPOSE. You are solely responsible for determining the
|
|
151
|
+
appropriateness of using or redistributing the Work and assume any
|
|
152
|
+
risks associated with Your exercise of permissions under this License.
|
|
153
|
+
|
|
154
|
+
8. Limitation of Liability. In no event and under no legal theory,
|
|
155
|
+
whether in tort (including negligence), contract, or otherwise,
|
|
156
|
+
unless required by applicable law (such as deliberate and grossly
|
|
157
|
+
negligent acts) or agreed to in writing, shall any Contributor be
|
|
158
|
+
liable to You for damages, including any direct, indirect, special,
|
|
159
|
+
incidental, or consequential damages of any character arising as a
|
|
160
|
+
result of this License or out of the use or inability to use the
|
|
161
|
+
Work (including but not limited to damages for loss of goodwill,
|
|
162
|
+
work stoppage, computer failure or malfunction, or any and all
|
|
163
|
+
other commercial damages or losses), even if such Contributor
|
|
164
|
+
has been advised of the possibility of such damages.
|
|
165
|
+
|
|
166
|
+
9. Accepting Warranty or Additional Liability. While redistributing
|
|
167
|
+
the Work or Derivative Works thereof, You may choose to offer,
|
|
168
|
+
and charge a fee for, acceptance of support, warranty, indemnity,
|
|
169
|
+
or other liability obligations and/or rights consistent with this
|
|
170
|
+
License. However, in accepting such obligations, You may act only
|
|
171
|
+
on Your own behalf and on Your sole responsibility, not on behalf
|
|
172
|
+
of any other Contributor, and only if You agree to indemnify,
|
|
173
|
+
defend, and hold each Contributor harmless for any liability
|
|
174
|
+
incurred by, or claims asserted against, such Contributor by reason
|
|
175
|
+
of your accepting any such warranty or additional liability.
|
|
176
|
+
|
|
177
|
+
END OF TERMS AND CONDITIONS
|
|
178
|
+
|
|
179
|
+
APPENDIX: How to apply the Apache License to your work.
|
|
180
|
+
|
|
181
|
+
To apply the Apache License to your work, attach the following
|
|
182
|
+
boilerplate notice, with the fields enclosed by brackets "[]"
|
|
183
|
+
replaced with your own identifying information. (Don't include
|
|
184
|
+
the brackets!) The text should be enclosed in the appropriate
|
|
185
|
+
comment syntax for the file format. We also recommend that a
|
|
186
|
+
file or class name and description of purpose be included on the
|
|
187
|
+
same "printed page" as the copyright notice for easier
|
|
188
|
+
identification within third-party archives.
|
|
189
|
+
|
|
190
|
+
Copyright [yyyy] [name of copyright owner]
|
|
191
|
+
|
|
192
|
+
Licensed under the Apache License, Version 2.0 (the "License");
|
|
193
|
+
you may not use this file except in compliance with the License.
|
|
194
|
+
You may obtain a copy of the License at
|
|
195
|
+
|
|
196
|
+
http://www.apache.org/licenses/LICENSE-2.0
|
|
197
|
+
|
|
198
|
+
Unless required by applicable law or agreed to in writing, software
|
|
199
|
+
distributed under the License is distributed on an "AS IS" BASIS,
|
|
200
|
+
WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
|
|
201
|
+
See the License for the specific language governing permissions and
|
|
202
|
+
limitations under the License.
|
package/NOTICE
ADDED
package/README.md
ADDED
|
@@ -0,0 +1,58 @@
|
|
|
1
|
+
# @inflexa-ai/harness
|
|
2
|
+
|
|
3
|
+
`@inflexa-ai/harness` is the host-agnostic agent harness — the `runAgent` loop, durable workflows, the sandbox submit/recv protocol, and the provider interfaces. It is a **library, not a server**: it ships everything that does not depend on a particular host, and an embedder supplies the composition root, transport, and any non-local seam realizations.
|
|
4
|
+
|
|
5
|
+
## Run locally
|
|
6
|
+
|
|
7
|
+
Requirements:
|
|
8
|
+
|
|
9
|
+
- Node.js `>=24` (the runtime; Bun is used only to run tests)
|
|
10
|
+
- Postgres with pgvector (app tables + durable workflow state)
|
|
11
|
+
- a sandbox backend, selected by `SANDBOX_BACKEND` (`docker` | `k8s`)
|
|
12
|
+
- a chat/embedding provider — Anthropic, or any OpenAI-compatible endpoint
|
|
13
|
+
|
|
14
|
+
```bash
|
|
15
|
+
npm install @inflexa-ai/harness # or add file:../harness from an in-repo embedder
|
|
16
|
+
|
|
17
|
+
tsc -p tsconfig.json # build: emit dist/ from src/ (also `npm run build`)
|
|
18
|
+
bun test # run the test suite
|
|
19
|
+
```
|
|
20
|
+
|
|
21
|
+
The package emits `dist/` from `src/` and publishes only `dist`. Most configuration arrives through dependency objects passed to the composition point — the LLM backend, for instance, is a fully injected provider config (endpoint/key/model or a `LanguageModel` instance), not read from env; helper modules read conventional env vars (`DB_PG_*`, sandbox limits) — see `CONTEXT.md` and the specs for the catalog.
|
|
22
|
+
|
|
23
|
+
## Public surface
|
|
24
|
+
|
|
25
|
+
Import the curated, embedder-facing surface from the package root. Every deep subpath (`@inflexa-ai/harness/...`) stays importable for advanced wiring; the barrel is additive.
|
|
26
|
+
|
|
27
|
+
```ts
|
|
28
|
+
import {
|
|
29
|
+
assembleCoreRuntime, // host-neutral composition point
|
|
30
|
+
createConversationAgent,
|
|
31
|
+
createAnthropicProvider, // ChatProvider — Anthropic
|
|
32
|
+
createConfiguredAiSdkProvider, // ChatProvider — any OpenAI-compatible endpoint
|
|
33
|
+
createEmbeddingProvider,
|
|
34
|
+
createLocalRunAuthorizer, // RunAuthorizer seam (local default)
|
|
35
|
+
createNoopBillingResolver, // ResolveBilling seam
|
|
36
|
+
createNoopRunCharge, // RunCharge seam
|
|
37
|
+
createNoopArtifactRegistry, // ArtifactRegistry seam
|
|
38
|
+
UnavailablePreviewPublisher, // PreviewPublisher seam
|
|
39
|
+
createDbosRunLauncher, // shared RunLauncher
|
|
40
|
+
defineTool,
|
|
41
|
+
runAgent,
|
|
42
|
+
makeLocalAuth,
|
|
43
|
+
} from "@inflexa-ai/harness";
|
|
44
|
+
```
|
|
45
|
+
|
|
46
|
+
`assembleCoreRuntime` is the single composition point: it registers the durable workflows and builds the conversation agent over them. The harness declares **five capability seams** an embedder wires — `RunAuthorizer`, `ResolveBilling`, `ArtifactRegistry`, `RunCharge`, `PreviewPublisher` — plus the **shared `RunLauncher`** (one host-neutral realization, `createDbosRunLauncher`). Local, dependency-free realizations of all five ship from the barrel; an embedder constructs them (or its own) and passes them in. The harness only ever sees the interface.
|
|
47
|
+
|
|
48
|
+
## How it executes
|
|
49
|
+
|
|
50
|
+
Chat is a plain in-process turn (`prepareChatTurn` → `runAgent` → `appendTurn`); the harness ships no HTTP layer, so the host owns the route. Compute-heavy work runs as **durable workflows** — `executeAnalysis` starts a child workflow per plan step once its dependencies have completed, and each step drives a sandbox agent inside a container. The same `runAgent` primitive runs in both modes; durability and the event sink are injected, so the loop body is identical.
|
|
51
|
+
|
|
52
|
+
The sandbox protocol is submit-then-retrieve, which is what lets a long run survive a host restart: the host `POST /exec`s a command and retrieves the result over one of two transports — **poll** (the default: the host asks, the sandbox initiates nothing and needs no network egress) or **callback** (opt-in: the sandbox POSTs signed callbacks to an ingress the embedder runs). Both exec endpoints are HMAC signature-authenticated. See the [`harness-sandbox-exec`](./openspec/specs/harness-sandbox-exec/) spec.
|
|
53
|
+
|
|
54
|
+
## Further reading
|
|
55
|
+
|
|
56
|
+
- [`CONTEXT.md`](./CONTEXT.md) — domain glossary and load-bearing patterns
|
|
57
|
+
- [`openspec/specs/`](./openspec/specs/) — feature specs and the source of truth for architectural decisions
|
|
58
|
+
- [`CLAUDE.md`](./CLAUDE.md) — working conventions, public-interface map, and the seam/session model
|
|
@@ -0,0 +1,105 @@
|
|
|
1
|
+
/**
|
|
2
|
+
* The conversation agent — the harness composition root.
|
|
3
|
+
*
|
|
4
|
+
* `createConversationAgent` is the one place dependencies are exploded apart
|
|
5
|
+
* (see the harness-durable-runtime spec): it receives the shared deps once — `ChatProvider`, `Pool`,
|
|
6
|
+
* `EmbeddingProvider`, the model id — and hands each tool exactly what it
|
|
7
|
+
* needs. Pure leaf tools take nothing; dependency-bearing tools get their
|
|
8
|
+
* factory inputs. By the time `runAgent` sees a tool it is fully dep-bound;
|
|
9
|
+
* the wiring lines below *are* the dependency graph, made visible.
|
|
10
|
+
*
|
|
11
|
+
* The system prompt is static composition — SOUL kernel + SOUL conversational
|
|
12
|
+
* + the conversation prompt — with no processor pipeline.
|
|
13
|
+
*
|
|
14
|
+
* `executePlan` is wired here — it launches the DBOS `executeAnalysis` parent
|
|
15
|
+
* workflow under `workflowId = runId` (the bare run UUID) through the
|
|
16
|
+
* `RunLauncher` seam and returns the runId (results are pull-only via
|
|
17
|
+
* `inspectRun` on a later turn). `run_ephemeral`
|
|
18
|
+
* is wired here too — it mints a run authorization, starts the turn-scoped DBOS
|
|
19
|
+
* `ephemeral` workflow, and awaits the result inline; chat disconnect cancels
|
|
20
|
+
* the workflow and it is never recovered. `iterateReport` is wired here too — in-process Nunjucks
|
|
21
|
+
* rendering driven by the in-process `report-builder` agent (no sandbox);
|
|
22
|
+
* the 4 custom report tools (`build_report`, `submit_report`,
|
|
23
|
+
* `preview_snapshot`, `mint_preview_url`) plus the version-fs write tools
|
|
24
|
+
* (`write_file`, `edit_file`, `read_file`, `mkdir` from `createVersionFsTools`)
|
|
25
|
+
* are constructed inside the runner so they share closure-captured outcome
|
|
26
|
+
* state + preview-dir paths.
|
|
27
|
+
* The workspace read surface (`read_file`, `grep`, `workspace_search`) is
|
|
28
|
+
* wired here over the `WorkspaceFilesystem` seam.
|
|
29
|
+
*/
|
|
30
|
+
import type { Pool } from "pg";
|
|
31
|
+
import type { ExecuteAnalysisInput, ExecuteAnalysisResult } from "../workflows/execute-analysis.js";
|
|
32
|
+
import type { ResourcePolicy } from "../config/resource-limits.js";
|
|
33
|
+
import type { ChromeConfig } from "../lib/chrome.js";
|
|
34
|
+
import type { AgentDefinition } from "../loop/types.js";
|
|
35
|
+
import type { ChatProvider, EmbeddingProvider } from "../providers/types.js";
|
|
36
|
+
import type { WorkspaceFilesystem } from "../workspace/filesystem.js";
|
|
37
|
+
import type { ResolveWorkspaceRoot } from "../workspace/paths.js";
|
|
38
|
+
import { type BioToolKeys } from "../tools/bio/keys.js";
|
|
39
|
+
import type { RunAuthorizer } from "../execution/run-authorizer.js";
|
|
40
|
+
import type { RunLauncher } from "../execution/run-launcher.js";
|
|
41
|
+
import { type IterateReportDeps } from "../tools/iterate-report.js";
|
|
42
|
+
import type { EphemeralWorkflowInput, EphemeralResult } from "../execution/ephemeral-runner.js";
|
|
43
|
+
/** Canonical agent id — the single source of truth. */
|
|
44
|
+
export declare const CONVERSATION_AGENT_ID: "conversation-agent";
|
|
45
|
+
/** The shared dependencies the composition root explodes apart. */
|
|
46
|
+
export interface ConversationAgentDeps {
|
|
47
|
+
/** The LLM seam every loop-driving tool runs its sub-agent on. */
|
|
48
|
+
readonly provider: ChatProvider;
|
|
49
|
+
/** Postgres pool — plan persistence, run inspection, workspace index, working memory. */
|
|
50
|
+
readonly pool: Pool;
|
|
51
|
+
/** Embedding seam — workspace semantic search. */
|
|
52
|
+
readonly embedding: EmbeddingProvider;
|
|
53
|
+
/** Workspace filesystem read seam — `read_file` and `grep`. */
|
|
54
|
+
readonly workspaceFs: WorkspaceFilesystem;
|
|
55
|
+
/** Model id — provenance / metric label; the provider owns the wire model. */
|
|
56
|
+
readonly model: string;
|
|
57
|
+
/**
|
|
58
|
+
* Registered `executeAnalysis` workflow callable — produced by
|
|
59
|
+
* `registerExecuteAnalysis` (wired by `assembleCoreRuntime`). `executePlan`
|
|
60
|
+
* launches it through the `RunLauncher` seam to start the run.
|
|
61
|
+
*/
|
|
62
|
+
readonly executeAnalysisWorkflow: (input: ExecuteAnalysisInput) => Promise<ExecuteAnalysisResult>;
|
|
63
|
+
/**
|
|
64
|
+
* Registered `ephemeral` workflow — `run_ephemeral` mints a run authorization,
|
|
65
|
+
* starts it, and awaits the result inline within the chat turn.
|
|
66
|
+
*/
|
|
67
|
+
readonly ephemeralWorkflow: (input: EphemeralWorkflowInput) => Promise<EphemeralResult>;
|
|
68
|
+
/** Workspace-root resolution seam (see workspace/paths.ts). */
|
|
69
|
+
readonly resolveWorkspaceRoot: ResolveWorkspaceRoot;
|
|
70
|
+
/**
|
|
71
|
+
* Async-edge run-authorization seam — injected, not constructed here.
|
|
72
|
+
* `execute_plan` and `run_ephemeral` turn the caller's opaque auth into a
|
|
73
|
+
* durable `RunSession` through it. The managed root injects the platform
|
|
74
|
+
* realization; the OSS root injects the local one.
|
|
75
|
+
*/
|
|
76
|
+
readonly runAuthorizer: RunAuthorizer;
|
|
77
|
+
/**
|
|
78
|
+
* Durable-run launch seam — `execute_plan` and `run_ephemeral` start their
|
|
79
|
+
* workflows through it so the durability engine stays out of the tools.
|
|
80
|
+
*/
|
|
81
|
+
readonly runLauncher: RunLauncher;
|
|
82
|
+
/**
|
|
83
|
+
* Preview-publishing seam factory for `iterate_report` — injected, not
|
|
84
|
+
* constructed here. The managed root closes its platform deps over this; the
|
|
85
|
+
* OSS root returns the "unavailable" publisher.
|
|
86
|
+
*/
|
|
87
|
+
readonly createPreviewPublisher: IterateReportDeps["createPreviewPublisher"];
|
|
88
|
+
/** API keys for the external bio/chem data sources. */
|
|
89
|
+
readonly bioKeys: BioToolKeys;
|
|
90
|
+
/** Root templates dir for in-process report rendering (`iterateReport`). */
|
|
91
|
+
readonly templatesDir: string;
|
|
92
|
+
/** Skills root; the in-process report-builder gets `report-html` skill tools. */
|
|
93
|
+
readonly skillsDir: string;
|
|
94
|
+
/** Headless-Chrome config for report snapshot/preview rendering. */
|
|
95
|
+
readonly chrome: ChromeConfig;
|
|
96
|
+
/**
|
|
97
|
+
* Host resource policy — per-step ceilings + machine budget. `generate_plan`
|
|
98
|
+
* states the ceilings to the planner and validates against them;
|
|
99
|
+
* `execute_plan` snapshots the budget into the workflow input. Absent,
|
|
100
|
+
* planning guidance and scheduling keep their legacy behavior.
|
|
101
|
+
*/
|
|
102
|
+
readonly resourcePolicy?: ResourcePolicy;
|
|
103
|
+
}
|
|
104
|
+
/** Build the conversation `AgentDefinition` with every tool fully dep-bound. */
|
|
105
|
+
export declare function createConversationAgent(deps: ConversationAgentDeps): AgentDefinition;
|
|
@@ -0,0 +1,140 @@
|
|
|
1
|
+
/**
|
|
2
|
+
* The conversation agent — the harness composition root.
|
|
3
|
+
*
|
|
4
|
+
* `createConversationAgent` is the one place dependencies are exploded apart
|
|
5
|
+
* (see the harness-durable-runtime spec): it receives the shared deps once — `ChatProvider`, `Pool`,
|
|
6
|
+
* `EmbeddingProvider`, the model id — and hands each tool exactly what it
|
|
7
|
+
* needs. Pure leaf tools take nothing; dependency-bearing tools get their
|
|
8
|
+
* factory inputs. By the time `runAgent` sees a tool it is fully dep-bound;
|
|
9
|
+
* the wiring lines below *are* the dependency graph, made visible.
|
|
10
|
+
*
|
|
11
|
+
* The system prompt is static composition — SOUL kernel + SOUL conversational
|
|
12
|
+
* + the conversation prompt — with no processor pipeline.
|
|
13
|
+
*
|
|
14
|
+
* `executePlan` is wired here — it launches the DBOS `executeAnalysis` parent
|
|
15
|
+
* workflow under `workflowId = runId` (the bare run UUID) through the
|
|
16
|
+
* `RunLauncher` seam and returns the runId (results are pull-only via
|
|
17
|
+
* `inspectRun` on a later turn). `run_ephemeral`
|
|
18
|
+
* is wired here too — it mints a run authorization, starts the turn-scoped DBOS
|
|
19
|
+
* `ephemeral` workflow, and awaits the result inline; chat disconnect cancels
|
|
20
|
+
* the workflow and it is never recovered. `iterateReport` is wired here too — in-process Nunjucks
|
|
21
|
+
* rendering driven by the in-process `report-builder` agent (no sandbox);
|
|
22
|
+
* the 4 custom report tools (`build_report`, `submit_report`,
|
|
23
|
+
* `preview_snapshot`, `mint_preview_url`) plus the version-fs write tools
|
|
24
|
+
* (`write_file`, `edit_file`, `read_file`, `mkdir` from `createVersionFsTools`)
|
|
25
|
+
* are constructed inside the runner so they share closure-captured outcome
|
|
26
|
+
* state + preview-dir paths.
|
|
27
|
+
* The workspace read surface (`read_file`, `grep`, `workspace_search`) is
|
|
28
|
+
* wired here over the `WorkspaceFilesystem` seam.
|
|
29
|
+
*/
|
|
30
|
+
import { createWorkingMemory } from "../memory/working-memory.js";
|
|
31
|
+
import { conversationPrompt } from "../prompts/conversation.js";
|
|
32
|
+
import { composeSystemPrompt } from "./system-prompt.js";
|
|
33
|
+
// Bio-lookup leaf tools (pure — no dependencies).
|
|
34
|
+
import { searchGeneTool, searchPathwayTool, lookupGoTermTool, searchInteractionsTool, searchCompoundsTool, getBioactivityTool, searchTargetsTool, getMechanismTool, getDrugInfoTool, searchPubchemCompoundTool, getPubchemCrossRefsTool, getPubchemAssaysTool, searchOpenTargetsTool, getTargetSafetyTool, searchPharmgkbTool, searchFaersTool, searchClinicalTrialsTool, searchGeoDatasetsTool, searchDgidbTool, searchBgeeExpressionTool, getImpcKoProfileTool, checkSafetyPanelTool, } from "../tools/bio/index.js";
|
|
35
|
+
import { createNcbiTools, createChemDbTools } from "../tools/bio/keys.js";
|
|
36
|
+
// Dependency-bearing tool factories.
|
|
37
|
+
import { createGeneratePlanTool, createLiteratureReviewerTool, createInspectRunTool, createGenerateAnalogyReportTool } from "../tools/research/index.js";
|
|
38
|
+
import { createFileStatTool, createGrepTool, createListFilesTool, createReadFileTool, createShowPlanTool, createWorkspaceSearchTool, showFileTool, } from "../tools/workspace/index.js";
|
|
39
|
+
import { showUserTool } from "../tools/display/index.js";
|
|
40
|
+
import { createUpdateWorkingMemoryTool } from "../tools/memory/index.js";
|
|
41
|
+
import { createExecutePlanTool } from "../tools/execute-plan.js";
|
|
42
|
+
import { createRunEphemeralTool } from "../tools/run-ephemeral.js";
|
|
43
|
+
import { createIterateReportTool } from "../tools/iterate-report.js";
|
|
44
|
+
/** Canonical agent id — the single source of truth. */
|
|
45
|
+
export const CONVERSATION_AGENT_ID = "conversation-agent";
|
|
46
|
+
/** Runaway guard — heavy tool-driving turns need generous headroom. */
|
|
47
|
+
const CONVERSATION_MAX_ITERATIONS = 50;
|
|
48
|
+
/** Build the conversation `AgentDefinition` with every tool fully dep-bound. */
|
|
49
|
+
export function createConversationAgent(deps) {
|
|
50
|
+
const { provider, pool, embedding, workspaceFs, model, executeAnalysisWorkflow, ephemeralWorkflow, resolveWorkspaceRoot, runAuthorizer, runLauncher, createPreviewPublisher, bioKeys, templatesDir, skillsDir, chrome, resourcePolicy, } = deps;
|
|
51
|
+
const workingMemory = createWorkingMemory(pool);
|
|
52
|
+
const ncbi = createNcbiTools(bioKeys);
|
|
53
|
+
const chemDb = createChemDbTools(bioKeys);
|
|
54
|
+
const tools = [
|
|
55
|
+
// Bio-lookup.
|
|
56
|
+
searchGeneTool,
|
|
57
|
+
searchPathwayTool,
|
|
58
|
+
lookupGoTermTool,
|
|
59
|
+
searchInteractionsTool,
|
|
60
|
+
ncbi.searchPubMed,
|
|
61
|
+
ncbi.getArticleDetails,
|
|
62
|
+
ncbi.getArticleFullText,
|
|
63
|
+
// ChEMBL.
|
|
64
|
+
searchCompoundsTool,
|
|
65
|
+
getBioactivityTool,
|
|
66
|
+
searchTargetsTool,
|
|
67
|
+
getMechanismTool,
|
|
68
|
+
getDrugInfoTool,
|
|
69
|
+
// PubChem.
|
|
70
|
+
searchPubchemCompoundTool,
|
|
71
|
+
getPubchemCrossRefsTool,
|
|
72
|
+
getPubchemAssaysTool,
|
|
73
|
+
// Translational medicine.
|
|
74
|
+
searchOpenTargetsTool,
|
|
75
|
+
getTargetSafetyTool,
|
|
76
|
+
searchPharmgkbTool,
|
|
77
|
+
searchFaersTool,
|
|
78
|
+
searchClinicalTrialsTool,
|
|
79
|
+
searchGeoDatasetsTool,
|
|
80
|
+
searchDgidbTool,
|
|
81
|
+
// Preclinical.
|
|
82
|
+
searchBgeeExpressionTool,
|
|
83
|
+
getImpcKoProfileTool,
|
|
84
|
+
// Off-target liability.
|
|
85
|
+
checkSafetyPanelTool,
|
|
86
|
+
// EPA CompTox.
|
|
87
|
+
chemDb.searchToxcast,
|
|
88
|
+
chemDb.searchCtxHazard,
|
|
89
|
+
chemDb.searchCtxChemical,
|
|
90
|
+
chemDb.searchCtxExposure,
|
|
91
|
+
// Execution.
|
|
92
|
+
createInspectRunTool(pool),
|
|
93
|
+
createGeneratePlanTool({ provider, pool, model, resourcePolicy }),
|
|
94
|
+
createExecutePlanTool({
|
|
95
|
+
pool,
|
|
96
|
+
executeAnalysisWorkflow,
|
|
97
|
+
runAuthorizer,
|
|
98
|
+
runLauncher,
|
|
99
|
+
resourcePolicy,
|
|
100
|
+
}),
|
|
101
|
+
createRunEphemeralTool({
|
|
102
|
+
workflow: ephemeralWorkflow,
|
|
103
|
+
runAuthorizer,
|
|
104
|
+
runLauncher,
|
|
105
|
+
}),
|
|
106
|
+
createIterateReportTool({
|
|
107
|
+
provider,
|
|
108
|
+
pool,
|
|
109
|
+
resolveWorkspaceRoot,
|
|
110
|
+
model,
|
|
111
|
+
templatesDir,
|
|
112
|
+
skillsDir,
|
|
113
|
+
chrome,
|
|
114
|
+
createPreviewPublisher,
|
|
115
|
+
}),
|
|
116
|
+
// Display.
|
|
117
|
+
showUserTool,
|
|
118
|
+
createShowPlanTool(pool),
|
|
119
|
+
showFileTool,
|
|
120
|
+
// Batch literature/biology research (sub-agent as a loop-driving tool).
|
|
121
|
+
createLiteratureReviewerTool({ provider, model, bioKeys }),
|
|
122
|
+
// Cross-domain analogy generation (sub-agent as a loop-driving tool).
|
|
123
|
+
createGenerateAnalogyReportTool({ provider, model, bioKeys }),
|
|
124
|
+
// Workspace semantic search + raw read/grep over the read seam.
|
|
125
|
+
createWorkspaceSearchTool(pool, embedding),
|
|
126
|
+
createReadFileTool(workspaceFs),
|
|
127
|
+
createListFilesTool(workspaceFs),
|
|
128
|
+
createFileStatTool(workspaceFs),
|
|
129
|
+
createGrepTool(workspaceFs),
|
|
130
|
+
// Working memory.
|
|
131
|
+
createUpdateWorkingMemoryTool(workingMemory),
|
|
132
|
+
];
|
|
133
|
+
return {
|
|
134
|
+
id: CONVERSATION_AGENT_ID,
|
|
135
|
+
systemPrompt: composeSystemPrompt(conversationPrompt),
|
|
136
|
+
model,
|
|
137
|
+
tools,
|
|
138
|
+
maxIterations: CONVERSATION_MAX_ITERATIONS,
|
|
139
|
+
};
|
|
140
|
+
}
|
|
@@ -0,0 +1,32 @@
|
|
|
1
|
+
/**
|
|
2
|
+
* Report Builder Agent — in-process templating agent (no sandbox).
|
|
3
|
+
*
|
|
4
|
+
* Authors HTML reports via Jinja2 templating. Runs in the Cortex Node
|
|
5
|
+
* process — file IO is in-process via the `versionFs` tool roster, rendering
|
|
6
|
+
* is Node-side via Nunjucks (`build_report` tool), and visual validation
|
|
7
|
+
* uses headless Chrome via the `preview_snapshot` tool.
|
|
8
|
+
*
|
|
9
|
+
* The agent receives a complete brief from iterate-report's pre-flight
|
|
10
|
+
* (assets staged, columns parsed, sections fully composed) and has no
|
|
11
|
+
* discovery surface — its workspace is rooted at the version directory.
|
|
12
|
+
*
|
|
13
|
+
* NOT a sandbox-agent catalog member (per design Decision #2 — not
|
|
14
|
+
* plannable). The full tool roster is constructed inside the runner so
|
|
15
|
+
* each tool shares the runner's closure-captured outcome state and
|
|
16
|
+
* preview-dir paths; this factory just packages the result into a plain
|
|
17
|
+
* `AgentDefinition`.
|
|
18
|
+
*/
|
|
19
|
+
import type { AgentDefinition } from "../loop/types.js";
|
|
20
|
+
import type { Tool } from "../tools/define-tool.js";
|
|
21
|
+
export declare const REPORT_BUILDER_AGENT_ID = "report-builder";
|
|
22
|
+
export interface CreateReportBuilderAgentDeps {
|
|
23
|
+
/** Model id — provenance / metric label; the provider owns the wire model. */
|
|
24
|
+
readonly model: string;
|
|
25
|
+
/**
|
|
26
|
+
* Full tool roster — the 4 custom report tools plus the in-process
|
|
27
|
+
* versionFs surface, all constructed inside the runner so they close
|
|
28
|
+
* over the iteration's outcome state and preview-dir paths.
|
|
29
|
+
*/
|
|
30
|
+
readonly tools: readonly Tool[];
|
|
31
|
+
}
|
|
32
|
+
export declare function createReportBuilderAgent(deps: CreateReportBuilderAgentDeps): AgentDefinition;
|
|
@@ -0,0 +1,31 @@
|
|
|
1
|
+
/**
|
|
2
|
+
* Report Builder Agent — in-process templating agent (no sandbox).
|
|
3
|
+
*
|
|
4
|
+
* Authors HTML reports via Jinja2 templating. Runs in the Cortex Node
|
|
5
|
+
* process — file IO is in-process via the `versionFs` tool roster, rendering
|
|
6
|
+
* is Node-side via Nunjucks (`build_report` tool), and visual validation
|
|
7
|
+
* uses headless Chrome via the `preview_snapshot` tool.
|
|
8
|
+
*
|
|
9
|
+
* The agent receives a complete brief from iterate-report's pre-flight
|
|
10
|
+
* (assets staged, columns parsed, sections fully composed) and has no
|
|
11
|
+
* discovery surface — its workspace is rooted at the version directory.
|
|
12
|
+
*
|
|
13
|
+
* NOT a sandbox-agent catalog member (per design Decision #2 — not
|
|
14
|
+
* plannable). The full tool roster is constructed inside the runner so
|
|
15
|
+
* each tool shares the runner's closure-captured outcome state and
|
|
16
|
+
* preview-dir paths; this factory just packages the result into a plain
|
|
17
|
+
* `AgentDefinition`.
|
|
18
|
+
*/
|
|
19
|
+
import { reportBuilderPrompt } from "../prompts/report-builder.js";
|
|
20
|
+
export const REPORT_BUILDER_AGENT_ID = "report-builder";
|
|
21
|
+
/** Runaway guard — Jinja recovery may take several build/edit cycles. */
|
|
22
|
+
const REPORT_BUILDER_MAX_ITERATIONS = 75;
|
|
23
|
+
export function createReportBuilderAgent(deps) {
|
|
24
|
+
return {
|
|
25
|
+
id: REPORT_BUILDER_AGENT_ID,
|
|
26
|
+
systemPrompt: reportBuilderPrompt,
|
|
27
|
+
model: deps.model,
|
|
28
|
+
tools: deps.tools,
|
|
29
|
+
maxIterations: REPORT_BUILDER_MAX_ITERATIONS,
|
|
30
|
+
};
|
|
31
|
+
}
|
|
@@ -0,0 +1,23 @@
|
|
|
1
|
+
/**
|
|
2
|
+
* Test-only `SandboxAgentDeps` builder. Hands every dependency a stub so
|
|
3
|
+
* `createSandboxAgent` builds without touching Postgres, the network, or
|
|
4
|
+
* a real sandbox.
|
|
5
|
+
*/
|
|
6
|
+
import type { Pool } from "pg";
|
|
7
|
+
import type { ChatProvider } from "../../../providers/types.js";
|
|
8
|
+
import type { SandboxClient } from "../../../sandbox/client.js";
|
|
9
|
+
import type { WorkspaceFilesystem } from "../../../workspace/filesystem.js";
|
|
10
|
+
import type { SandboxAgentDeps } from "../shared.js";
|
|
11
|
+
export declare function makeFakeSandboxClient(): SandboxClient;
|
|
12
|
+
export declare function makeFakeWorkspaceFs(): WorkspaceFilesystem;
|
|
13
|
+
export declare function makeFakeChatProvider(): ChatProvider;
|
|
14
|
+
export declare function makeFakePool(): Pool;
|
|
15
|
+
export interface MakeDepsOverrides {
|
|
16
|
+
readonly model?: string;
|
|
17
|
+
readonly analysisId?: string;
|
|
18
|
+
readonly runId?: string;
|
|
19
|
+
readonly stepId?: string;
|
|
20
|
+
readonly workflowId?: string;
|
|
21
|
+
readonly allowedWritePrefix?: string;
|
|
22
|
+
}
|
|
23
|
+
export declare function makeFakeSandboxAgentDeps(over?: MakeDepsOverrides): SandboxAgentDeps;
|