@erosolaraijs/cure 2.3.1 → 2.5.0

package/dist/capabilities/multimodalOncologyModule.js.map

@@ -0,0 +1 @@
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package/dist/capabilities/palliativeCareModule.d.ts

@@ -0,0 +1,216 @@
+/**
+ * Comprehensive Palliative Care and Pain Management Module
+ *
+ * ╔═══════════════════════════════════════════════════════════════════════════════╗
+ * ║  PALLIATIVE CARE - COMFORT AND QUALITY OF LIFE FOR ALL PATIENTS             ║
+ * ╠═══════════════════════════════════════════════════════════════════════════════╣
+ * ║  This module provides:                                                        ║
+ * ║  - Comprehensive pain management (nociceptive, neuropathic, visceral)        ║
+ * ║  - Symptom cluster management by cancer type                                 ║
+ * ║  - Refractory symptom escalation protocols                                   ║
+ * ║  - End-of-life care and hospice transition                                   ║
+ * ║  - Goals of care communication frameworks                                    ║
+ * ║  - Advance care planning integration                                         ║
+ * ╚═══════════════════════════════════════════════════════════════════════════════╝
+ */
+export interface PainAssessment {
+    location: string[];
+    intensity: number;
+    quality: PainQuality[];
+    temporalPattern: 'Constant' | 'Intermittent' | 'Breakthrough' | 'Incident';
+    aggravatingFactors: string[];
+    relievingFactors: string[];
+    functionalImpact: FunctionalImpact;
+    psychologicalImpact: string[];
+    painType: PainType[];
+}
+export type PainQuality = 'Sharp' | 'Dull' | 'Aching' | 'Burning' | 'Shooting' | 'Stabbing' | 'Throbbing' | 'Cramping' | 'Pressure' | 'Tingling' | 'Numbness';
+export type PainType = 'Nociceptive-Somatic' | 'Nociceptive-Visceral' | 'Neuropathic-Peripheral' | 'Neuropathic-Central' | 'Mixed' | 'Bone' | 'Inflammatory';
+export interface FunctionalImpact {
+    sleepDisturbance: 0 | 1 | 2 | 3;
+    mobilityImpairment: 0 | 1 | 2 | 3;
+    selfCareImpairment: 0 | 1 | 2 | 3;
+    socialImpairment: 0 | 1 | 2 | 3;
+    overallQoL: number;
+}
+export interface PainManagementProtocol {
+    painType: PainType;
+    severity: 'Mild' | 'Moderate' | 'Severe';
+    firstLine: PainIntervention[];
+    secondLine: PainIntervention[];
+    thirdLine: PainIntervention[];
+    adjuvants: AdjuvantTherapy[];
+    interventional: InterventionalProcedure[];
+    monitoring: PainMonitoring;
+}
+export interface PainIntervention {
+    medication: string;
+    class: string;
+    startingDose: string;
+    titrationSchedule: string;
+    maxDose: string;
+    routeOptions: string[];
+    precautions: string[];
+    contraindications: string[];
+    monitoringRequired: string[];
+}
+export interface AdjuvantTherapy {
+    medication: string;
+    indication: string;
+    dose: string;
+    mechanism: string;
+    evidence: string;
+}
+export interface InterventionalProcedure {
+    procedure: string;
+    indication: string;
+    technique: string;
+    expectedBenefit: string;
+    duration: string;
+    risks: string[];
+    contraindications: string[];
+}
+export interface PainMonitoring {
+    assessmentFrequency: string;
+    tools: string[];
+    escalationCriteria: string[];
+    deescalationCriteria: string[];
+}
+export declare const WHO_PAIN_LADDER: PainManagementProtocol[];
+export declare const NEUROPATHIC_PAIN_PROTOCOLS: PainManagementProtocol[];
+export interface CIPNProtocol {
+    causingAgent: string;
+    riskFactors: string[];
+    prevention: PreventionStrategy[];
+    treatment: PainIntervention[];
+    doseModification: DoseModificationGuideline[];
+    prognosis: string;
+}
+export interface PreventionStrategy {
+    intervention: string;
+    evidence: string;
+    recommendation: 'Recommended' | 'May Consider' | 'Not Recommended';
+}
+export interface DoseModificationGuideline {
+    grade: number;
+    description: string;
+    action: string;
+}
+export declare const CIPN_PROTOCOLS: CIPNProtocol[];
+export interface BonePainProtocol {
+    indication: string;
+    pharmacological: PainIntervention[];
+    boneTargeted: BoneTargetedTherapy[];
+    radiation: RadiationForPain[];
+    interventional: InterventionalProcedure[];
+    surgical: string[];
+}
+export interface BoneTargetedTherapy {
+    agent: string;
+    class: string;
+    dose: string;
+    frequency: string;
+    painBenefit: string;
+    skeletalEventReduction: string;
+    precautions: string[];
+}
+export interface RadiationForPain {
+    technique: string;
+    dose: string;
+    fractionation: string;
+    responseRate: string;
+    timeToResponse: string;
+    retreatmentOption: boolean;
+}
+export declare const BONE_PAIN_PROTOCOL: BonePainProtocol;
+export interface SymptomCluster {
+    cancerType: string;
+    commonSymptoms: SymptomManagement[];
+    psychologicalSymptoms: string[];
+    interventions: ClusterIntervention[];
+}
+export interface SymptomManagement {
+    symptom: string;
+    prevalence: string;
+    firstLineManagement: string[];
+    secondLineManagement: string[];
+    refractory: string[];
+}
+export interface ClusterIntervention {
+    type: string;
+    intervention: string;
+    evidence: string;
+}
+export declare const CANCER_SYMPTOM_CLUSTERS: SymptomCluster[];
+export interface EndOfLifeProtocol {
+    phase: 'Last weeks' | 'Last days' | 'Actively dying';
+    clinicalIndicators: string[];
+    symptomPriorities: string[];
+    medicationChanges: MedicationTransition;
+    familySupport: string[];
+    practicalConsiderations: string[];
+}
+export interface MedicationTransition {
+    currentRoute: string;
+    alternativeRoutes: string[];
+    essentialMedications: string[];
+    medicationsToDiscontinue: string[];
+    prnProtocols: PRNProtocol[];
+}
+export interface PRNProtocol {
+    symptom: string;
+    medication: string;
+    dose: string;
+    route: string;
+    frequency: string;
+    maxDose24h: string;
+}
+export declare const END_OF_LIFE_PROTOCOLS: EndOfLifeProtocol[];
+export interface PalliativeSedationProtocol {
+    indications: string[];
+    prerequisites: string[];
+    sedationTypes: SedationType[];
+    medications: SedationMedication[];
+    monitoring: string[];
+    documentation: string[];
+    ethicalConsiderations: string[];
+}
+export interface SedationType {
+    type: string;
+    description: string;
+    indication: string;
+}
+export interface SedationMedication {
+    medication: string;
+    startingDose: string;
+    titration: string;
+    maxDose: string;
+    notes: string;
+}
+export declare const PALLIATIVE_SEDATION_PROTOCOL: PalliativeSedationProtocol;
+export interface OpioidEquivalence {
+    opioid: string;
+    oralMorphineEquivalent: number;
+    routes: RouteConversion[];
+    specialConsiderations: string[];
+}
+export interface RouteConversion {
+    from: string;
+    to: string;
+    ratio: number;
+}
+export declare const OPIOID_EQUIVALENCE_TABLE: OpioidEquivalence[];
+export declare class PalliativeCareEngine {
+    assessPain(assessment: PainAssessment): PainManagementProtocol | undefined;
+    getCIPNProtocol(agent: string): CIPNProtocol | undefined;
+    getBonePainProtocol(): BonePainProtocol;
+    getSymptomCluster(cancerType: string): SymptomCluster | undefined;
+    getEndOfLifeProtocol(phase: EndOfLifeProtocol['phase']): EndOfLifeProtocol | undefined;
+    calculateOpioidConversion(fromOpioid: string, fromDose: number, fromRoute: string, toOpioid: string, toRoute: string): {
+        dose: number;
+        notes: string[];
+    };
+    getPalliativeSedationProtocol(): PalliativeSedationProtocol;
+}
+export declare const palliativeCareEngine: PalliativeCareEngine;
+//# sourceMappingURL=palliativeCareModule.d.ts.map

package/dist/capabilities/palliativeCareModule.d.ts.map

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