finishm 0.0.1

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (554) hide show
  1. checksums.yaml +7 -0
  2. data/.document +5 -0
  3. data/.gitmodules +3 -0
  4. data/.rspec +1 -0
  5. data/Gemfile +31 -0
  6. data/LICENSE.txt +20 -0
  7. data/README.md +59 -0
  8. data/Rakefile +51 -0
  9. data/VERSION +1 -0
  10. data/bin/assembly_visualiser +106 -0
  11. data/bin/check_primer_combinations.rb +73 -0
  12. data/bin/contig_joiner.rb +244 -0
  13. data/bin/contigs_against_assembly.rb +153 -0
  14. data/bin/finishm +143 -0
  15. data/bin/finishm_assembler +55 -0
  16. data/bin/finishm_gap_closer.rb +241 -0
  17. data/bin/kmer_abundance_file_tool.rb +49 -0
  18. data/bin/kmer_pattern_to_assembly.rb +377 -0
  19. data/bin/kmer_profile_finder.rb +92 -0
  20. data/bin/kmers_count_parse.d +52 -0
  21. data/bin/kmers_count_tabulate.d +123 -0
  22. data/bin/kmers_count_tabulate.rb +84 -0
  23. data/bin/pcr_result_parser.rb +108 -0
  24. data/bin/primer_finder.rb +119 -0
  25. data/bin/read_selection_by_kmer.d +174 -0
  26. data/bin/scaffold_by_pattern.rb +119 -0
  27. data/bin/scaffold_connection_possibilities_to_knowns.rb +193 -0
  28. data/bin/scaffold_end_coverages.rb +69 -0
  29. data/bin/trail_validator.rb +84 -0
  30. data/ext/mkrf_conf.rb +56 -0
  31. data/ext/src/Makefile +140 -0
  32. data/ext/src/src/allocArray.c +305 -0
  33. data/ext/src/src/allocArray.h +86 -0
  34. data/ext/src/src/autoOpen.c +107 -0
  35. data/ext/src/src/autoOpen.h +18 -0
  36. data/ext/src/src/binarySequences.c +813 -0
  37. data/ext/src/src/binarySequences.h +125 -0
  38. data/ext/src/src/concatenatedGraph.c +233 -0
  39. data/ext/src/src/concatenatedGraph.h +30 -0
  40. data/ext/src/src/concatenatedPreGraph.c +262 -0
  41. data/ext/src/src/concatenatedPreGraph.h +29 -0
  42. data/ext/src/src/correctedGraph.c +2643 -0
  43. data/ext/src/src/correctedGraph.h +32 -0
  44. data/ext/src/src/dfib.c +509 -0
  45. data/ext/src/src/dfib.h +69 -0
  46. data/ext/src/src/dfibHeap.c +89 -0
  47. data/ext/src/src/dfibHeap.h +39 -0
  48. data/ext/src/src/dfibpriv.h +105 -0
  49. data/ext/src/src/fib.c +628 -0
  50. data/ext/src/src/fib.h +78 -0
  51. data/ext/src/src/fibHeap.c +79 -0
  52. data/ext/src/src/fibHeap.h +41 -0
  53. data/ext/src/src/fibpriv.h +110 -0
  54. data/ext/src/src/globals.h +154 -0
  55. data/ext/src/src/graph.c +3932 -0
  56. data/ext/src/src/graph.h +233 -0
  57. data/ext/src/src/graphReConstruction.c +1472 -0
  58. data/ext/src/src/graphReConstruction.h +30 -0
  59. data/ext/src/src/graphStats.c +2167 -0
  60. data/ext/src/src/graphStats.h +72 -0
  61. data/ext/src/src/graphStructures.h +52 -0
  62. data/ext/src/src/kmer.c +652 -0
  63. data/ext/src/src/kmer.h +73 -0
  64. data/ext/src/src/kmerOccurenceTable.c +236 -0
  65. data/ext/src/src/kmerOccurenceTable.h +44 -0
  66. data/ext/src/src/kseq.h +223 -0
  67. data/ext/src/src/locallyCorrectedGraph.c +557 -0
  68. data/ext/src/src/locallyCorrectedGraph.h +40 -0
  69. data/ext/src/src/passageMarker.c +677 -0
  70. data/ext/src/src/passageMarker.h +137 -0
  71. data/ext/src/src/preGraph.c +1717 -0
  72. data/ext/src/src/preGraph.h +106 -0
  73. data/ext/src/src/preGraphConstruction.c +990 -0
  74. data/ext/src/src/preGraphConstruction.h +26 -0
  75. data/ext/src/src/probe_node_finder.c +84 -0
  76. data/ext/src/src/probe_node_finder.h +6 -0
  77. data/ext/src/src/readCoherentGraph.c +557 -0
  78. data/ext/src/src/readCoherentGraph.h +30 -0
  79. data/ext/src/src/readSet.c +1734 -0
  80. data/ext/src/src/readSet.h +67 -0
  81. data/ext/src/src/readToNode.c +218 -0
  82. data/ext/src/src/readToNode.h +35 -0
  83. data/ext/src/src/recycleBin.c +199 -0
  84. data/ext/src/src/recycleBin.h +58 -0
  85. data/ext/src/src/roadMap.c +342 -0
  86. data/ext/src/src/roadMap.h +65 -0
  87. data/ext/src/src/run.c +318 -0
  88. data/ext/src/src/run.h +52 -0
  89. data/ext/src/src/run2.c +744 -0
  90. data/ext/src/src/runReadToNode.c +29 -0
  91. data/ext/src/src/scaffold.c +1876 -0
  92. data/ext/src/src/scaffold.h +64 -0
  93. data/ext/src/src/shortReadPairs.c +1243 -0
  94. data/ext/src/src/shortReadPairs.h +32 -0
  95. data/ext/src/src/splay.c +259 -0
  96. data/ext/src/src/splay.h +43 -0
  97. data/ext/src/src/splayTable.c +1315 -0
  98. data/ext/src/src/splayTable.h +31 -0
  99. data/ext/src/src/tightString.c +362 -0
  100. data/ext/src/src/tightString.h +82 -0
  101. data/ext/src/src/utility.c +199 -0
  102. data/ext/src/src/utility.h +98 -0
  103. data/ext/src/third-party/zlib-1.2.3/ChangeLog +855 -0
  104. data/ext/src/third-party/zlib-1.2.3/FAQ +339 -0
  105. data/ext/src/third-party/zlib-1.2.3/INDEX +51 -0
  106. data/ext/src/third-party/zlib-1.2.3/Makefile +154 -0
  107. data/ext/src/third-party/zlib-1.2.3/Makefile.in +154 -0
  108. data/ext/src/third-party/zlib-1.2.3/README +125 -0
  109. data/ext/src/third-party/zlib-1.2.3/adler32.c +149 -0
  110. data/ext/src/third-party/zlib-1.2.3/adler32.o +0 -0
  111. data/ext/src/third-party/zlib-1.2.3/algorithm.txt +209 -0
  112. data/ext/src/third-party/zlib-1.2.3/amiga/Makefile.pup +66 -0
  113. data/ext/src/third-party/zlib-1.2.3/amiga/Makefile.sas +65 -0
  114. data/ext/src/third-party/zlib-1.2.3/as400/bndsrc +132 -0
  115. data/ext/src/third-party/zlib-1.2.3/as400/compile.clp +123 -0
  116. data/ext/src/third-party/zlib-1.2.3/as400/readme.txt +111 -0
  117. data/ext/src/third-party/zlib-1.2.3/as400/zlib.inc +331 -0
  118. data/ext/src/third-party/zlib-1.2.3/compress.c +79 -0
  119. data/ext/src/third-party/zlib-1.2.3/compress.o +0 -0
  120. data/ext/src/third-party/zlib-1.2.3/configure +459 -0
  121. data/ext/src/third-party/zlib-1.2.3/contrib/README.contrib +71 -0
  122. data/ext/src/third-party/zlib-1.2.3/contrib/ada/buffer_demo.adb +106 -0
  123. data/ext/src/third-party/zlib-1.2.3/contrib/ada/mtest.adb +156 -0
  124. data/ext/src/third-party/zlib-1.2.3/contrib/ada/read.adb +156 -0
  125. data/ext/src/third-party/zlib-1.2.3/contrib/ada/readme.txt +65 -0
  126. data/ext/src/third-party/zlib-1.2.3/contrib/ada/test.adb +463 -0
  127. data/ext/src/third-party/zlib-1.2.3/contrib/ada/zlib-streams.adb +225 -0
  128. data/ext/src/third-party/zlib-1.2.3/contrib/ada/zlib-streams.ads +114 -0
  129. data/ext/src/third-party/zlib-1.2.3/contrib/ada/zlib-thin.adb +141 -0
  130. data/ext/src/third-party/zlib-1.2.3/contrib/ada/zlib-thin.ads +450 -0
  131. data/ext/src/third-party/zlib-1.2.3/contrib/ada/zlib.adb +701 -0
  132. data/ext/src/third-party/zlib-1.2.3/contrib/ada/zlib.ads +328 -0
  133. data/ext/src/third-party/zlib-1.2.3/contrib/ada/zlib.gpr +20 -0
  134. data/ext/src/third-party/zlib-1.2.3/contrib/asm586/README.586 +43 -0
  135. data/ext/src/third-party/zlib-1.2.3/contrib/asm586/match.S +364 -0
  136. data/ext/src/third-party/zlib-1.2.3/contrib/asm686/README.686 +34 -0
  137. data/ext/src/third-party/zlib-1.2.3/contrib/asm686/match.S +329 -0
  138. data/ext/src/third-party/zlib-1.2.3/contrib/blast/Makefile +8 -0
  139. data/ext/src/third-party/zlib-1.2.3/contrib/blast/README +4 -0
  140. data/ext/src/third-party/zlib-1.2.3/contrib/blast/blast.c +444 -0
  141. data/ext/src/third-party/zlib-1.2.3/contrib/blast/blast.h +71 -0
  142. data/ext/src/third-party/zlib-1.2.3/contrib/blast/test.pk +0 -0
  143. data/ext/src/third-party/zlib-1.2.3/contrib/blast/test.txt +1 -0
  144. data/ext/src/third-party/zlib-1.2.3/contrib/delphi/ZLib.pas +557 -0
  145. data/ext/src/third-party/zlib-1.2.3/contrib/delphi/ZLibConst.pas +11 -0
  146. data/ext/src/third-party/zlib-1.2.3/contrib/delphi/readme.txt +76 -0
  147. data/ext/src/third-party/zlib-1.2.3/contrib/delphi/zlibd32.mak +93 -0
  148. data/ext/src/third-party/zlib-1.2.3/contrib/dotzlib/DotZLib.build +33 -0
  149. data/ext/src/third-party/zlib-1.2.3/contrib/dotzlib/DotZLib.chm +0 -0
  150. data/ext/src/third-party/zlib-1.2.3/contrib/dotzlib/DotZLib.sln +21 -0
  151. data/ext/src/third-party/zlib-1.2.3/contrib/dotzlib/DotZLib/AssemblyInfo.cs +58 -0
  152. data/ext/src/third-party/zlib-1.2.3/contrib/dotzlib/DotZLib/ChecksumImpl.cs +202 -0
  153. data/ext/src/third-party/zlib-1.2.3/contrib/dotzlib/DotZLib/CircularBuffer.cs +83 -0
  154. data/ext/src/third-party/zlib-1.2.3/contrib/dotzlib/DotZLib/CodecBase.cs +198 -0
  155. data/ext/src/third-party/zlib-1.2.3/contrib/dotzlib/DotZLib/Deflater.cs +106 -0
  156. data/ext/src/third-party/zlib-1.2.3/contrib/dotzlib/DotZLib/DotZLib.cs +288 -0
  157. data/ext/src/third-party/zlib-1.2.3/contrib/dotzlib/DotZLib/DotZLib.csproj +141 -0
  158. data/ext/src/third-party/zlib-1.2.3/contrib/dotzlib/DotZLib/GZipStream.cs +301 -0
  159. data/ext/src/third-party/zlib-1.2.3/contrib/dotzlib/DotZLib/Inflater.cs +105 -0
  160. data/ext/src/third-party/zlib-1.2.3/contrib/dotzlib/DotZLib/UnitTests.cs +274 -0
  161. data/ext/src/third-party/zlib-1.2.3/contrib/dotzlib/LICENSE_1_0.txt +23 -0
  162. data/ext/src/third-party/zlib-1.2.3/contrib/dotzlib/readme.txt +58 -0
  163. data/ext/src/third-party/zlib-1.2.3/contrib/infback9/README +1 -0
  164. data/ext/src/third-party/zlib-1.2.3/contrib/infback9/infback9.c +608 -0
  165. data/ext/src/third-party/zlib-1.2.3/contrib/infback9/infback9.h +37 -0
  166. data/ext/src/third-party/zlib-1.2.3/contrib/infback9/inffix9.h +107 -0
  167. data/ext/src/third-party/zlib-1.2.3/contrib/infback9/inflate9.h +47 -0
  168. data/ext/src/third-party/zlib-1.2.3/contrib/infback9/inftree9.c +323 -0
  169. data/ext/src/third-party/zlib-1.2.3/contrib/infback9/inftree9.h +55 -0
  170. data/ext/src/third-party/zlib-1.2.3/contrib/inflate86/inffas86.c +1157 -0
  171. data/ext/src/third-party/zlib-1.2.3/contrib/inflate86/inffast.S +1368 -0
  172. data/ext/src/third-party/zlib-1.2.3/contrib/iostream/test.cpp +24 -0
  173. data/ext/src/third-party/zlib-1.2.3/contrib/iostream/zfstream.cpp +329 -0
  174. data/ext/src/third-party/zlib-1.2.3/contrib/iostream/zfstream.h +128 -0
  175. data/ext/src/third-party/zlib-1.2.3/contrib/iostream2/zstream.h +307 -0
  176. data/ext/src/third-party/zlib-1.2.3/contrib/iostream2/zstream_test.cpp +25 -0
  177. data/ext/src/third-party/zlib-1.2.3/contrib/iostream3/README +35 -0
  178. data/ext/src/third-party/zlib-1.2.3/contrib/iostream3/TODO +17 -0
  179. data/ext/src/third-party/zlib-1.2.3/contrib/iostream3/test.cc +50 -0
  180. data/ext/src/third-party/zlib-1.2.3/contrib/iostream3/zfstream.cc +479 -0
  181. data/ext/src/third-party/zlib-1.2.3/contrib/iostream3/zfstream.h +466 -0
  182. data/ext/src/third-party/zlib-1.2.3/contrib/masm686/match.asm +413 -0
  183. data/ext/src/third-party/zlib-1.2.3/contrib/masmx64/bld_ml64.bat +2 -0
  184. data/ext/src/third-party/zlib-1.2.3/contrib/masmx64/gvmat64.asm +513 -0
  185. data/ext/src/third-party/zlib-1.2.3/contrib/masmx64/gvmat64.obj +0 -0
  186. data/ext/src/third-party/zlib-1.2.3/contrib/masmx64/inffas8664.c +186 -0
  187. data/ext/src/third-party/zlib-1.2.3/contrib/masmx64/inffasx64.asm +392 -0
  188. data/ext/src/third-party/zlib-1.2.3/contrib/masmx64/inffasx64.obj +0 -0
  189. data/ext/src/third-party/zlib-1.2.3/contrib/masmx64/readme.txt +28 -0
  190. data/ext/src/third-party/zlib-1.2.3/contrib/masmx86/bld_ml32.bat +2 -0
  191. data/ext/src/third-party/zlib-1.2.3/contrib/masmx86/gvmat32.asm +972 -0
  192. data/ext/src/third-party/zlib-1.2.3/contrib/masmx86/gvmat32.obj +0 -0
  193. data/ext/src/third-party/zlib-1.2.3/contrib/masmx86/gvmat32c.c +62 -0
  194. data/ext/src/third-party/zlib-1.2.3/contrib/masmx86/inffas32.asm +1083 -0
  195. data/ext/src/third-party/zlib-1.2.3/contrib/masmx86/inffas32.obj +0 -0
  196. data/ext/src/third-party/zlib-1.2.3/contrib/masmx86/mkasm.bat +3 -0
  197. data/ext/src/third-party/zlib-1.2.3/contrib/masmx86/readme.txt +21 -0
  198. data/ext/src/third-party/zlib-1.2.3/contrib/minizip/ChangeLogUnzip +67 -0
  199. data/ext/src/third-party/zlib-1.2.3/contrib/minizip/Makefile +25 -0
  200. data/ext/src/third-party/zlib-1.2.3/contrib/minizip/crypt.h +132 -0
  201. data/ext/src/third-party/zlib-1.2.3/contrib/minizip/ioapi.c +177 -0
  202. data/ext/src/third-party/zlib-1.2.3/contrib/minizip/ioapi.h +75 -0
  203. data/ext/src/third-party/zlib-1.2.3/contrib/minizip/iowin32.c +270 -0
  204. data/ext/src/third-party/zlib-1.2.3/contrib/minizip/iowin32.h +21 -0
  205. data/ext/src/third-party/zlib-1.2.3/contrib/minizip/miniunz.c +585 -0
  206. data/ext/src/third-party/zlib-1.2.3/contrib/minizip/minizip.c +420 -0
  207. data/ext/src/third-party/zlib-1.2.3/contrib/minizip/mztools.c +281 -0
  208. data/ext/src/third-party/zlib-1.2.3/contrib/minizip/mztools.h +31 -0
  209. data/ext/src/third-party/zlib-1.2.3/contrib/minizip/unzip.c +1598 -0
  210. data/ext/src/third-party/zlib-1.2.3/contrib/minizip/unzip.h +354 -0
  211. data/ext/src/third-party/zlib-1.2.3/contrib/minizip/zip.c +1219 -0
  212. data/ext/src/third-party/zlib-1.2.3/contrib/minizip/zip.h +235 -0
  213. data/ext/src/third-party/zlib-1.2.3/contrib/pascal/example.pas +599 -0
  214. data/ext/src/third-party/zlib-1.2.3/contrib/pascal/readme.txt +76 -0
  215. data/ext/src/third-party/zlib-1.2.3/contrib/pascal/zlibd32.mak +93 -0
  216. data/ext/src/third-party/zlib-1.2.3/contrib/pascal/zlibpas.pas +236 -0
  217. data/ext/src/third-party/zlib-1.2.3/contrib/puff/Makefile +8 -0
  218. data/ext/src/third-party/zlib-1.2.3/contrib/puff/README +63 -0
  219. data/ext/src/third-party/zlib-1.2.3/contrib/puff/puff.c +837 -0
  220. data/ext/src/third-party/zlib-1.2.3/contrib/puff/puff.h +31 -0
  221. data/ext/src/third-party/zlib-1.2.3/contrib/puff/zeros.raw +0 -0
  222. data/ext/src/third-party/zlib-1.2.3/contrib/testzlib/testzlib.c +275 -0
  223. data/ext/src/third-party/zlib-1.2.3/contrib/testzlib/testzlib.txt +10 -0
  224. data/ext/src/third-party/zlib-1.2.3/contrib/untgz/Makefile +14 -0
  225. data/ext/src/third-party/zlib-1.2.3/contrib/untgz/Makefile.msc +17 -0
  226. data/ext/src/third-party/zlib-1.2.3/contrib/untgz/untgz.c +674 -0
  227. data/ext/src/third-party/zlib-1.2.3/contrib/vstudio/readme.txt +73 -0
  228. data/ext/src/third-party/zlib-1.2.3/contrib/vstudio/vc7/miniunz.vcproj +126 -0
  229. data/ext/src/third-party/zlib-1.2.3/contrib/vstudio/vc7/minizip.vcproj +126 -0
  230. data/ext/src/third-party/zlib-1.2.3/contrib/vstudio/vc7/testzlib.vcproj +126 -0
  231. data/ext/src/third-party/zlib-1.2.3/contrib/vstudio/vc7/zlib.rc +32 -0
  232. data/ext/src/third-party/zlib-1.2.3/contrib/vstudio/vc7/zlibstat.vcproj +246 -0
  233. data/ext/src/third-party/zlib-1.2.3/contrib/vstudio/vc7/zlibvc.def +92 -0
  234. data/ext/src/third-party/zlib-1.2.3/contrib/vstudio/vc7/zlibvc.sln +78 -0
  235. data/ext/src/third-party/zlib-1.2.3/contrib/vstudio/vc7/zlibvc.vcproj +445 -0
  236. data/ext/src/third-party/zlib-1.2.3/contrib/vstudio/vc8/miniunz.vcproj +566 -0
  237. data/ext/src/third-party/zlib-1.2.3/contrib/vstudio/vc8/minizip.vcproj +563 -0
  238. data/ext/src/third-party/zlib-1.2.3/contrib/vstudio/vc8/testzlib.vcproj +948 -0
  239. data/ext/src/third-party/zlib-1.2.3/contrib/vstudio/vc8/testzlibdll.vcproj +567 -0
  240. data/ext/src/third-party/zlib-1.2.3/contrib/vstudio/vc8/zlib.rc +32 -0
  241. data/ext/src/third-party/zlib-1.2.3/contrib/vstudio/vc8/zlibstat.vcproj +870 -0
  242. data/ext/src/third-party/zlib-1.2.3/contrib/vstudio/vc8/zlibvc.def +92 -0
  243. data/ext/src/third-party/zlib-1.2.3/contrib/vstudio/vc8/zlibvc.sln +144 -0
  244. data/ext/src/third-party/zlib-1.2.3/contrib/vstudio/vc8/zlibvc.vcproj +1219 -0
  245. data/ext/src/third-party/zlib-1.2.3/crc32.c +423 -0
  246. data/ext/src/third-party/zlib-1.2.3/crc32.h +441 -0
  247. data/ext/src/third-party/zlib-1.2.3/crc32.o +0 -0
  248. data/ext/src/third-party/zlib-1.2.3/deflate.c +1736 -0
  249. data/ext/src/third-party/zlib-1.2.3/deflate.h +331 -0
  250. data/ext/src/third-party/zlib-1.2.3/deflate.o +0 -0
  251. data/ext/src/third-party/zlib-1.2.3/example +0 -0
  252. data/ext/src/third-party/zlib-1.2.3/example.c +565 -0
  253. data/ext/src/third-party/zlib-1.2.3/examples/README.examples +42 -0
  254. data/ext/src/third-party/zlib-1.2.3/examples/fitblk.c +233 -0
  255. data/ext/src/third-party/zlib-1.2.3/examples/gun.c +693 -0
  256. data/ext/src/third-party/zlib-1.2.3/examples/gzappend.c +500 -0
  257. data/ext/src/third-party/zlib-1.2.3/examples/gzjoin.c +448 -0
  258. data/ext/src/third-party/zlib-1.2.3/examples/gzlog.c +413 -0
  259. data/ext/src/third-party/zlib-1.2.3/examples/gzlog.h +58 -0
  260. data/ext/src/third-party/zlib-1.2.3/examples/zlib_how.html +523 -0
  261. data/ext/src/third-party/zlib-1.2.3/examples/zpipe.c +191 -0
  262. data/ext/src/third-party/zlib-1.2.3/examples/zran.c +404 -0
  263. data/ext/src/third-party/zlib-1.2.3/gzio.c +1026 -0
  264. data/ext/src/third-party/zlib-1.2.3/gzio.o +0 -0
  265. data/ext/src/third-party/zlib-1.2.3/infback.c +623 -0
  266. data/ext/src/third-party/zlib-1.2.3/infback.o +0 -0
  267. data/ext/src/third-party/zlib-1.2.3/inffast.c +318 -0
  268. data/ext/src/third-party/zlib-1.2.3/inffast.h +11 -0
  269. data/ext/src/third-party/zlib-1.2.3/inffast.o +0 -0
  270. data/ext/src/third-party/zlib-1.2.3/inffixed.h +94 -0
  271. data/ext/src/third-party/zlib-1.2.3/inflate.c +1368 -0
  272. data/ext/src/third-party/zlib-1.2.3/inflate.h +115 -0
  273. data/ext/src/third-party/zlib-1.2.3/inflate.o +0 -0
  274. data/ext/src/third-party/zlib-1.2.3/inftrees.c +329 -0
  275. data/ext/src/third-party/zlib-1.2.3/inftrees.h +55 -0
  276. data/ext/src/third-party/zlib-1.2.3/inftrees.o +0 -0
  277. data/ext/src/third-party/zlib-1.2.3/libz.a +0 -0
  278. data/ext/src/third-party/zlib-1.2.3/make_vms.com +461 -0
  279. data/ext/src/third-party/zlib-1.2.3/minigzip +0 -0
  280. data/ext/src/third-party/zlib-1.2.3/minigzip.c +322 -0
  281. data/ext/src/third-party/zlib-1.2.3/msdos/Makefile.bor +109 -0
  282. data/ext/src/third-party/zlib-1.2.3/msdos/Makefile.dj2 +104 -0
  283. data/ext/src/third-party/zlib-1.2.3/msdos/Makefile.emx +69 -0
  284. data/ext/src/third-party/zlib-1.2.3/msdos/Makefile.msc +106 -0
  285. data/ext/src/third-party/zlib-1.2.3/msdos/Makefile.tc +94 -0
  286. data/ext/src/third-party/zlib-1.2.3/old/Makefile.riscos +151 -0
  287. data/ext/src/third-party/zlib-1.2.3/old/README +3 -0
  288. data/ext/src/third-party/zlib-1.2.3/old/descrip.mms +48 -0
  289. data/ext/src/third-party/zlib-1.2.3/old/os2/Makefile.os2 +136 -0
  290. data/ext/src/third-party/zlib-1.2.3/old/os2/zlib.def +51 -0
  291. data/ext/src/third-party/zlib-1.2.3/old/visual-basic.txt +160 -0
  292. data/ext/src/third-party/zlib-1.2.3/old/zlib.html +971 -0
  293. data/ext/src/third-party/zlib-1.2.3/projects/README.projects +41 -0
  294. data/ext/src/third-party/zlib-1.2.3/projects/visualc6/README.txt +73 -0
  295. data/ext/src/third-party/zlib-1.2.3/projects/visualc6/example.dsp +278 -0
  296. data/ext/src/third-party/zlib-1.2.3/projects/visualc6/minigzip.dsp +278 -0
  297. data/ext/src/third-party/zlib-1.2.3/projects/visualc6/zlib.dsp +609 -0
  298. data/ext/src/third-party/zlib-1.2.3/projects/visualc6/zlib.dsw +59 -0
  299. data/ext/src/third-party/zlib-1.2.3/qnx/package.qpg +141 -0
  300. data/ext/src/third-party/zlib-1.2.3/trees.c +1219 -0
  301. data/ext/src/third-party/zlib-1.2.3/trees.h +128 -0
  302. data/ext/src/third-party/zlib-1.2.3/trees.o +0 -0
  303. data/ext/src/third-party/zlib-1.2.3/uncompr.c +61 -0
  304. data/ext/src/third-party/zlib-1.2.3/uncompr.o +0 -0
  305. data/ext/src/third-party/zlib-1.2.3/win32/DLL_FAQ.txt +397 -0
  306. data/ext/src/third-party/zlib-1.2.3/win32/Makefile.bor +107 -0
  307. data/ext/src/third-party/zlib-1.2.3/win32/Makefile.emx +69 -0
  308. data/ext/src/third-party/zlib-1.2.3/win32/Makefile.gcc +141 -0
  309. data/ext/src/third-party/zlib-1.2.3/win32/Makefile.msc +126 -0
  310. data/ext/src/third-party/zlib-1.2.3/win32/VisualC.txt +3 -0
  311. data/ext/src/third-party/zlib-1.2.3/win32/zlib.def +60 -0
  312. data/ext/src/third-party/zlib-1.2.3/win32/zlib1.rc +39 -0
  313. data/ext/src/third-party/zlib-1.2.3/zconf.h +332 -0
  314. data/ext/src/third-party/zlib-1.2.3/zconf.in.h +332 -0
  315. data/ext/src/third-party/zlib-1.2.3/zlib.3 +159 -0
  316. data/ext/src/third-party/zlib-1.2.3/zlib.h +1357 -0
  317. data/ext/src/third-party/zlib-1.2.3/zutil.c +318 -0
  318. data/ext/src/third-party/zlib-1.2.3/zutil.h +269 -0
  319. data/ext/src/third-party/zlib-1.2.3/zutil.o +0 -0
  320. data/lib/assembly/a_b_visualiser.rb +169 -0
  321. data/lib/assembly/acyclic_connection_finder.rb +81 -0
  322. data/lib/assembly/all_orfs.rb +615 -0
  323. data/lib/assembly/bad_format_writer.rb +46 -0
  324. data/lib/assembly/bam_probe_read_selector.rb +48 -0
  325. data/lib/assembly/bubbly_assembler.rb +842 -0
  326. data/lib/assembly/c_probe_node_finder.rb +38 -0
  327. data/lib/assembly/connection_interpreter.rb +350 -0
  328. data/lib/assembly/contig_printer.rb +400 -0
  329. data/lib/assembly/coverage_based_graph_filter.rb +68 -0
  330. data/lib/assembly/depth_first_search.rb +63 -0
  331. data/lib/assembly/dijkstra.rb +216 -0
  332. data/lib/assembly/fluffer.rb +253 -0
  333. data/lib/assembly/graph_explorer.rb +85 -0
  334. data/lib/assembly/graph_generator.rb +315 -0
  335. data/lib/assembly/height_finder.rb +355 -0
  336. data/lib/assembly/hybrid_velvet_graph.rb +70 -0
  337. data/lib/assembly/input_genome.rb +182 -0
  338. data/lib/assembly/kmer_coverage_based_path_filter.rb +65 -0
  339. data/lib/assembly/node_finder.rb +171 -0
  340. data/lib/assembly/oriented_node_trail.rb +507 -0
  341. data/lib/assembly/paired_end_assembler.rb +53 -0
  342. data/lib/assembly/paired_end_neighbour_finder.rb +176 -0
  343. data/lib/assembly/probed_graph.rb +105 -0
  344. data/lib/assembly/read_input.rb +79 -0
  345. data/lib/assembly/read_to_node.rb +37 -0
  346. data/lib/assembly/scaffold_breaker.rb +126 -0
  347. data/lib/assembly/sequence_hasher.rb +71 -0
  348. data/lib/assembly/single_coherent_paths_between_nodes.rb +533 -0
  349. data/lib/assembly/single_coherent_wanderer.rb +261 -0
  350. data/lib/assembly/single_ended_assembler.rb +441 -0
  351. data/lib/assembly/velvet_c_binding.rb +54 -0
  352. data/lib/assembly/velvet_graph_sequence_extractor.rb +123 -0
  353. data/lib/external/VERSION +1 -0
  354. data/lib/finishm/assemble.rb +224 -0
  355. data/lib/finishm/explore.rb +217 -0
  356. data/lib/finishm/finisher.rb +303 -0
  357. data/lib/finishm/fluff.rb +122 -0
  358. data/lib/finishm/gapfiller.rb +325 -0
  359. data/lib/finishm/orfs_finder.rb +88 -0
  360. data/lib/finishm/path_counter.rb +90 -0
  361. data/lib/finishm/primers.rb +425 -0
  362. data/lib/finishm/primers_check.rb +176 -0
  363. data/lib/finishm/roundup.rb +344 -0
  364. data/lib/finishm/sequence.rb +142 -0
  365. data/lib/finishm/visualise.rb +430 -0
  366. data/lib/finishm/wander.rb +270 -0
  367. data/lib/kmer_abundance_pattern.rb +79 -0
  368. data/lib/kmer_multi_abundance_file.rb +48 -0
  369. data/lib/oligo_designer.rb +88 -0
  370. data/lib/priner.rb +66 -0
  371. data/spec/acyclic_connection_finder_spec.rb +551 -0
  372. data/spec/all_orfs_spec.rb +443 -0
  373. data/spec/assemble_spec.rb +186 -0
  374. data/spec/bubbly_assembler_spec.rb +707 -0
  375. data/spec/c_node_finder_spec.rb +58 -0
  376. data/spec/connection_interpreter_spec.rb +284 -0
  377. data/spec/contig_printer_spec.rb +291 -0
  378. data/spec/coverage_based_graph_filter_spec.rb +102 -0
  379. data/spec/data/6_3e4e5e6e.1vANME.bam +0 -0
  380. data/spec/data/6_3e4e5e6e.1vANME.bam.bai +0 -0
  381. data/spec/data/acyclic_connection_finder/1/probes.fa +5 -0
  382. data/spec/data/acyclic_connection_finder/1/random1.fa +2 -0
  383. data/spec/data/acyclic_connection_finder/1/random1.sammy.fa.gz +0 -0
  384. data/spec/data/acyclic_connection_finder/1/random2.fa +2 -0
  385. data/spec/data/acyclic_connection_finder/1/random2.sammy.fa.gz +0 -0
  386. data/spec/data/assembly/1_simple_bubble_uneven_coverage/random3000.fa +39 -0
  387. data/spec/data/assembly/1_simple_bubble_uneven_coverage/random3000.slightly_changed.fa +39 -0
  388. data/spec/data/assembly/1_simple_bubble_uneven_coverage/reads_combined.fa.gz +0 -0
  389. data/spec/data/assembly_visualiser/Contig_6_1_to_250.fa.kmers31 +220 -0
  390. data/spec/data/assembly_visualiser/Contig_7_1_to_250.fa.kmers31 +220 -0
  391. data/spec/data/assembly_visualiser/Graph +46 -0
  392. data/spec/data/assembly_visualiser/start_kmers1 +2 -0
  393. data/spec/data/bands.csv +1 -0
  394. data/spec/data/c_probe_node_finder/1/CnyUnifiedSeq +0 -0
  395. data/spec/data/c_probe_node_finder/1/CnyUnifiedSeq.names +544 -0
  396. data/spec/data/c_probe_node_finder/1/Graph2 +668 -0
  397. data/spec/data/c_probe_node_finder/1/LastGraph +668 -0
  398. data/spec/data/c_probe_node_finder/1/Log +756 -0
  399. data/spec/data/c_probe_node_finder/1/PreGraph +11 -0
  400. data/spec/data/c_probe_node_finder/1/Roadmaps +2009 -0
  401. data/spec/data/c_probe_node_finder/1/contigs.fa +29 -0
  402. data/spec/data/c_probe_node_finder/1/stats.txt +6 -0
  403. data/spec/data/contig_printer/1/HOWTO_RECREATE +17 -0
  404. data/spec/data/contig_printer/1/contigs.fa +4 -0
  405. data/spec/data/contig_printer/1/seq.fa +2408 -0
  406. data/spec/data/contig_printer/1/seq.fa.svg +153 -0
  407. data/spec/data/contig_printer/1/seq.fa.velvet/Graph2 +2953 -0
  408. data/spec/data/contig_printer/1/seq.fa.velvet/LastGraph +2953 -0
  409. data/spec/data/contig_printer/1/seq.fa.velvet/Log +21 -0
  410. data/spec/data/contig_printer/1/seq.fa.velvet/PreGraph +27 -0
  411. data/spec/data/contig_printer/1/seq.fa.velvet/Roadmaps +5182 -0
  412. data/spec/data/contig_printer/1/seq.fa.velvet/Sequences +3612 -0
  413. data/spec/data/contig_printer/1/seq.fa.velvet/contigs.fa +36 -0
  414. data/spec/data/contig_printer/1/seq.fa.velvet/stats.txt +14 -0
  415. data/spec/data/contig_printer/1/seq.faVseq2_1to550.fa.bam +0 -0
  416. data/spec/data/contig_printer/1/seq.faVseq2_1to550.fa.bam.bai +0 -0
  417. data/spec/data/contig_printer/1/seq.node12.fa +4 -0
  418. data/spec/data/contig_printer/1/seq1_1to550.fa +2 -0
  419. data/spec/data/contig_printer/1/seq2_1to550.fa +2 -0
  420. data/spec/data/contig_printer/1/seq2_1to550.fa.fai +1 -0
  421. data/spec/data/explore/1/2seqs.sammy.fa +12004 -0
  422. data/spec/data/explore/1/HOWTO_RECREATE.txt +6 -0
  423. data/spec/data/explore/1/a.fa +2 -0
  424. data/spec/data/explore/1/seq1_and_a.fa +3 -0
  425. data/spec/data/explore/1/seq2.fa +2 -0
  426. data/spec/data/fluff/1/2seqs.sammy.fa +12004 -0
  427. data/spec/data/fluff/1/HOWTO_RECREATE.txt +5 -0
  428. data/spec/data/fluff/1/seq1.fa +2 -0
  429. data/spec/data/fluff/1/seq2.fa +2 -0
  430. data/spec/data/gapfilling/1/reads.fa +171 -0
  431. data/spec/data/gapfilling/1/trail_with_Ns.fa +5 -0
  432. data/spec/data/gapfilling/1/velvetAssembly/Graph2 +130 -0
  433. data/spec/data/gapfilling/1/velvetAssembly/LastGraph +130 -0
  434. data/spec/data/gapfilling/1/velvetAssembly/Log +199 -0
  435. data/spec/data/gapfilling/1/velvetAssembly/PreGraph +7 -0
  436. data/spec/data/gapfilling/1/velvetAssembly/Roadmaps +239 -0
  437. data/spec/data/gapfilling/1/velvetAssembly/Sequences +281 -0
  438. data/spec/data/gapfilling/1/velvetAssembly/contigs.fa +12 -0
  439. data/spec/data/gapfilling/1/velvetAssembly/stats.txt +4 -0
  440. data/spec/data/gapfilling/2/HOWTO_recreate +17 -0
  441. data/spec/data/gapfilling/2/reference.fa +2 -0
  442. data/spec/data/gapfilling/2/reference_part1.fa +4 -0
  443. data/spec/data/gapfilling/2/reference_part2.fa +4 -0
  444. data/spec/data/gapfilling/2/sammy_reads.fa.gz +0 -0
  445. data/spec/data/gapfilling/2/with_gaps.fa +4 -0
  446. data/spec/data/gapfilling/3/HOWTO_recreate +4 -0
  447. data/spec/data/gapfilling/3/reads.fa.gz +0 -0
  448. data/spec/data/gapfilling/3/reference_part1.fa +4 -0
  449. data/spec/data/gapfilling/3/reference_part2.fa +4 -0
  450. data/spec/data/gapfilling/3/with_gaps.fa +4 -0
  451. data/spec/data/gapfilling/4/HOWTO_recreate +1 -0
  452. data/spec/data/gapfilling/4/reads.fa.gz +0 -0
  453. data/spec/data/gapfilling/5/HOWTO_RECREATE +7 -0
  454. data/spec/data/gapfilling/5/answer.fna +2 -0
  455. data/spec/data/gapfilling/5/gappy.fna +2 -0
  456. data/spec/data/gapfilling/5/reads.fa +17961 -0
  457. data/spec/data/gapfilling/5/velvet51_3.5/LastGraph +8337 -0
  458. data/spec/data/gapfilling/5/velvet51_3.5/Sequences +20921 -0
  459. data/spec/data/gapfilling/6/random1.fa +28 -0
  460. data/spec/data/gapfilling/6/random2.fa +28 -0
  461. data/spec/data/gapfilling/6/random_sequence_length_2000 +0 -0
  462. data/spec/data/gapfilling/6/reads.random1.fa.gz +0 -0
  463. data/spec/data/gapfilling/6/reads.random2.fa.gz +0 -0
  464. data/spec/data/gapfilling/6/to_gapfill.fa +22 -0
  465. data/spec/data/kmer_profile_to_assembly/multiple_abundance_file1.csv +2 -0
  466. data/spec/data/kmers_count1.csv +2 -0
  467. data/spec/data/kmers_count2.csv +3 -0
  468. data/spec/data/out +3 -0
  469. data/spec/data/positive_latching_pair.fa +2 -0
  470. data/spec/data/primers.csv +4 -0
  471. data/spec/data/read_selection_by_kmer/blacklist1.txt +1 -0
  472. data/spec/data/read_selection_by_kmer/input.fasta +6 -0
  473. data/spec/data/read_selection_by_kmer/whitelist1.txt +1 -0
  474. data/spec/data/read_selection_by_kmer/whitelist2.txt +2 -0
  475. data/spec/data/read_to_node/1_a_graph/HOWTO_RECREATE.txt +2 -0
  476. data/spec/data/read_to_node/1_a_graph/LastGraph +6695 -0
  477. data/spec/data/read_to_node/1_a_graph/ReadToNode.bin +0 -0
  478. data/spec/data/read_to_node/2_no_read256_or_259/HOWTO_RECREATE.txt +3 -0
  479. data/spec/data/read_to_node/2_no_read256_or_259/LastGraph +6693 -0
  480. data/spec/data/read_to_node/2_no_read256_or_259/ReadToNode.bin +0 -0
  481. data/spec/data/read_to_node/3_no_last_read/LastGraph +6694 -0
  482. data/spec/data/read_to_node/3_no_last_read/ReadToNode.bin +0 -0
  483. data/spec/data/t/details.txt +5 -0
  484. data/spec/data/t/details.txt.srt +5 -0
  485. data/spec/data/t/location.txt +3 -0
  486. data/spec/data/t/location.txt.srt +3 -0
  487. data/spec/data/tweak/1_gap_then_unscaffolded/answer.fa +2 -0
  488. data/spec/data/tweak/1_gap_then_unscaffolded/reads.fa.gz +0 -0
  489. data/spec/data/tweak/1_gap_then_unscaffolded/scaffolds.fa +6 -0
  490. data/spec/data/tweak/2_second_genome/answer2.fa +2 -0
  491. data/spec/data/tweak/2_second_genome/reads.fa.gz +0 -0
  492. data/spec/data/tweak/3_variant/answer.fa +2 -0
  493. data/spec/data/tweak/3_variant/lesser_answer.fa +2 -0
  494. data/spec/data/tweak/3_variant/reads.fa.gz +0 -0
  495. data/spec/data/tweak/3_variant/with_gaps.fa +2 -0
  496. data/spec/data/velvet_test_trails/Assem/Graph +17 -0
  497. data/spec/data/velvet_test_trails/Assem/Graph2 +40 -0
  498. data/spec/data/velvet_test_trails/Assem/LastGraph +40 -0
  499. data/spec/data/velvet_test_trails/Assem/Log +35 -0
  500. data/spec/data/velvet_test_trails/Assem/PreGraph +9 -0
  501. data/spec/data/velvet_test_trails/Assem/Roadmaps +89 -0
  502. data/spec/data/velvet_test_trails/Assem/Sequences +50 -0
  503. data/spec/data/velvet_test_trails/Assem/a.svg +53 -0
  504. data/spec/data/velvet_test_trails/Assem/contigs.fa +15 -0
  505. data/spec/data/velvet_test_trails/Assem/stats.txt +5 -0
  506. data/spec/data/velvet_test_trails/node_fwds.fa +8 -0
  507. data/spec/data/velvet_test_trails/node_seqs.fa +9 -0
  508. data/spec/data/velvet_test_trails/nodes_fwd_rev.fa +16 -0
  509. data/spec/data/velvet_test_trails/read1.fa +2 -0
  510. data/spec/data/velvet_test_trails/reads.fa +50 -0
  511. data/spec/data/velvet_test_trails_reverse/Assem/LastGraph +17 -0
  512. data/spec/data/velvet_test_trails_reverse/Assem/a.svg +53 -0
  513. data/spec/data/velvet_test_trails_reverse/reads_reversed.fa +10 -0
  514. data/spec/data/visualise/1/LastGraph +6695 -0
  515. data/spec/data/visualise/2_paired_end/HOWTO_RECREATE.txt +10 -0
  516. data/spec/data/visualise/2_paired_end/rand1.fa +2 -0
  517. data/spec/data/visualise/2_paired_end/rand2.fa +2 -0
  518. data/spec/data/visualise/2_paired_end/with_gaps.fa +8 -0
  519. data/spec/data/visualise/2_paired_end/with_gaps.read_pairs.fa.gz +0 -0
  520. data/spec/data/wander/1/random1.fa +2 -0
  521. data/spec/data/wander/1/random1.sammy.fa +804 -0
  522. data/spec/depth_first_search_spec.rb +190 -0
  523. data/spec/dijkstra_spec.rb +143 -0
  524. data/spec/explore_spec.rb +29 -0
  525. data/spec/fluffer_spec.rb +155 -0
  526. data/spec/gapfiller_spec.rb +107 -0
  527. data/spec/graph_explorer_spec.rb +475 -0
  528. data/spec/graph_generator_spec.rb +99 -0
  529. data/spec/height_finder_spec.rb +306 -0
  530. data/spec/kmer_abundance_pattern_spec.rb +56 -0
  531. data/spec/kmer_coverage_based_path_filter_spec.rb +73 -0
  532. data/spec/kmer_profile_finder_spec.rb +38 -0
  533. data/spec/kmers_count_tabulate_spec.rb +120 -0
  534. data/spec/oriented_node_trail_spec.rb +221 -0
  535. data/spec/paired_end_neighbours_spec.rb +126 -0
  536. data/spec/paths_between_nodes_spec.rb +349 -0
  537. data/spec/priner_spec.rb +7 -0
  538. data/spec/read_input_spec.rb +23 -0
  539. data/spec/read_selection_by_kmer_spec.rb +166 -0
  540. data/spec/read_to_node_spec.rb +35 -0
  541. data/spec/roundup_spec.rb +366 -0
  542. data/spec/scaffold_breaker_spec.rb +144 -0
  543. data/spec/sequence_spec.rb +43 -0
  544. data/spec/single_coherent_paths_between_nodes_spec.rb +492 -0
  545. data/spec/single_coherent_wanderer_spec.rb +120 -0
  546. data/spec/single_ended_assembler_spec.rb +398 -0
  547. data/spec/spec_helper.rb +310 -0
  548. data/spec/velvet_graph_sequence_extractor_spec.rb +80 -0
  549. data/spec/visualise_spec.rb +105 -0
  550. data/spec/wander_spec.rb +119 -0
  551. data/spec/watch_for_changes.sh +16 -0
  552. data/validation/fasta_compare.rb +72 -0
  553. data/validation/gapfill_simulate_perfect.rb +108 -0
  554. metadata +899 -0
@@ -0,0 +1,125 @@
1
+ /*
2
+ Copyright 2011 Convey Computer Corporation (info@conveycomputer.com)
3
+
4
+ This file is part of Velvet.
5
+
6
+ Velvet is free software; you can redistribute it and/or modify
7
+ it under the terms of the GNU General Public License as published by
8
+ the Free Software Foundation; either version 2 of the License, or
9
+ (at your option) any later version.
10
+
11
+ Velvet is distributed in the hope that it will be useful,
12
+ but WITHOUT ANY WARRANTY; without even the implied warranty of
13
+ MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
14
+ GNU General Public License for more details.
15
+
16
+ You should have received a copy of the GNU General Public License
17
+ along with Velvet; if not, write to the Free Software
18
+ Foundation, Inc., 51 Franklin St, Fifth Floor, Boston, MA 02110-1301 USA
19
+
20
+ */
21
+ #ifndef _BINARYSEQUENCES_H_
22
+ #define _BINARYSEQUENCES_H_
23
+
24
+ #include "recycleBin.h"
25
+
26
+ struct refInfo_st {
27
+ int32_t m_referenceID;
28
+ int32_t m_pos;
29
+ };
30
+ typedef struct refInfo_st RefInfo;
31
+
32
+
33
+ typedef struct {
34
+ Category m_numCategories;
35
+ uint32_t m_magic;
36
+ boolean m_bDoubleStrand;
37
+ boolean m_bColor;
38
+ uint64_t m_sequenceCnt;
39
+ uint64_t m_timeStamp;
40
+ uint64_t m_seqNuclStoreSize;
41
+ uint64_t m_minSeqLen;
42
+ uint64_t m_maxSeqLen;
43
+ uint64_t m_totalSeqLen;
44
+ boolean m_bFileWriteCompleted;
45
+ } CnyUnifiedSeqFileHeader;
46
+
47
+ // Reading
48
+ struct sequencesReader_st {
49
+ char * m_seqFilename;
50
+ FILE * m_pFile;
51
+ ReadSet * m_sequences;
52
+ boolean m_bIsBinary;
53
+ // following are only used by the binary code
54
+ char * m_namesFilename;
55
+ CnyUnifiedSeqFileHeader m_unifiedSeqFileHeader;
56
+ Category m_numCategories;
57
+ Category m_currCategory;
58
+ uint64_t m_minSeqLen;
59
+ uint64_t m_maxSeqLen;
60
+ uint8_t * m_pReadBuffer;
61
+ uint8_t * m_pReadBufEnd;
62
+ uint64_t m_readBufPos;
63
+ uint8_t * m_pCurrentReadPtr;
64
+ uint8_t * m_pNextReadPtr;
65
+ uint64_t m_currentNuclReadIdx;
66
+ uint64_t m_currentReadLength;
67
+ uint32_t m_refCnt;
68
+ boolean m_bIsRef;
69
+ char ** m_ppCurrString;
70
+ };
71
+
72
+ #define USF_READ_BUF_SIZE (64*1024)
73
+
74
+ ReadSet *importCnyReadSet(char *filename);
75
+ void getCnySeqNucl(SequencesReader *seqReadInfo, uint8_t *sequence);
76
+ uint32_t readCnySeqUint32(SequencesReader *seqReadInfo);
77
+ boolean advanceCnySeqCurrentRead(SequencesReader *seqReadInfo);
78
+ FILE *openCnySeqForRead(const char *fileName, CnyUnifiedSeqFileHeader *seqFileHeader);
79
+ void resetCnySeqCurrentRead(SequencesReader *seqReadInfo);
80
+
81
+ struct refInfoList_st {
82
+ RefInfo m_elem;
83
+ struct refInfoList_st *next;
84
+ };
85
+ typedef struct refInfoList_st RefInfoList;
86
+
87
+ // Writing
88
+ struct sequencesWriter_st {
89
+ FILE * m_pFile;
90
+ // following are only used by the binary code
91
+ FILE * m_nameFile;
92
+ CnyUnifiedSeqFileHeader m_unifiedSeqFileHeader;
93
+ uint64_t m_insertStartIndex;
94
+ uint64_t m_insertLength;
95
+ uint64_t m_insertLengthIndex;
96
+ uint64_t m_insertCurrentIndex;
97
+ uint32_t m_hostBuffersInUse;
98
+ uint32_t m_fileSegmentWriteIdx;
99
+ uint8_t * m_pWriteBuffer[3];
100
+ uint8_t * m_pHostBufPtr;
101
+ uint8_t * m_pHostLengthBufPtr;
102
+ uint8_t * m_pHostLengthBufPtrMax;
103
+ uint8_t * m_pHostBufPtrMax;
104
+ int64_t m_hostBufferFilePos[3];
105
+ RefInfoList * m_refInfoHead;
106
+ uint32_t m_refCnt;
107
+ boolean m_bIsRef;
108
+ Mask ** m_referenceMask;
109
+ Mask * m_current;
110
+ Coordinate m_position;
111
+ boolean m_openMask;
112
+ RecycleBin * m_maskMemory;
113
+ };
114
+ typedef struct sequencesWriter_st SequencesWriter;
115
+
116
+ SequencesWriter * openCnySeqForWrite(const char *unifiedSeqFileName);
117
+ void cnySeqInsertSequenceName(const char *name, IDnum readID, SequencesWriter *seqWriteInfo, Category cat);
118
+ void cnySeqInsertReferenceMask(SequencesWriter *seqWriteInfo, Mask *referenceMask);
119
+ void cnySeqInsertNucleotideString(const char *pReadBuf, SequencesWriter *seqWriteInfo);
120
+ void inputCnySeqFileStart(Category category, SequencesWriter *seqWriteInfo);
121
+ void cnySeqInsertStart(SequencesWriter *seqWriteInfo);
122
+ void cnySeqInsertEnd(SequencesWriter *seqWriteInfo);
123
+ void closeCnySeqForWrite(SequencesWriter *seqWriteInfo);
124
+
125
+ #endif
@@ -0,0 +1,233 @@
1
+ /*
2
+ Copyright 2007, 2008 Daniel Zerbino (zerbino@ebi.ac.uk)
3
+
4
+ This file is part of Velvet.
5
+
6
+ Velvet is free software; you can redistribute it and/or modify
7
+ it under the terms of the GNU General Public License as published by
8
+ the Free Software Foundation; either version 2 of the License, or
9
+ (at your option) any later version.
10
+
11
+ Velvet is distributed in the hope that it will be useful,
12
+ but WITHOUT ANY WARRANTY; without even the implied warranty of
13
+ MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
14
+ GNU General Public License for more details.
15
+
16
+ You should have received a copy of the GNU General Public License
17
+ along with Velvet; if not, write to the Free Software
18
+ Foundation, Inc., 51 Franklin St, Fifth Floor, Boston, MA 02110-1301 USA
19
+
20
+ */
21
+ #include <stdlib.h>
22
+ #include <stdio.h>
23
+
24
+ #include "globals.h"
25
+ #include "graph.h"
26
+ #include "passageMarker.h"
27
+ #include "utility.h"
28
+
29
+ // DEBUG
30
+ static boolean isLocallyInitial(PassageMarkerI marker) {
31
+ PassageMarkerI previous = getPreviousInSequence(marker);
32
+ return (previous == NULL_IDX
33
+ || getPassageMarkerFinish(previous) != getPassageMarkerStart(marker));
34
+ }
35
+
36
+ void concatenateReadStarts(Node * target, Node * source, Graph * graph)
37
+ {
38
+ IDnum sourceLength, targetLength;
39
+ ShortReadMarker *sourceArray, *targetArray, *marker;
40
+ IDnum index;
41
+ Coordinate position, nodeLength;
42
+
43
+ if (!readStartsAreActivated(graph))
44
+ return;
45
+
46
+ if (target == NULL || source == NULL)
47
+ return;
48
+
49
+ // Update Coordinates
50
+ sourceArray = getNodeReads(source, graph);
51
+ sourceLength = getNodeReadCount(source, graph);
52
+
53
+ nodeLength = getNodeLength(target);
54
+ for (index = 0; index < sourceLength; index++) {
55
+ marker = getShortReadMarkerAtIndex(sourceArray, index);
56
+ position = getShortReadMarkerPosition(marker);
57
+ if (position != -1) {
58
+ position += nodeLength;
59
+ setShortReadMarkerPosition(marker, position);
60
+ }
61
+ }
62
+
63
+ // Same but for symmetrical reads
64
+ targetArray = getNodeReads(getTwinNode(target), graph);
65
+ targetLength = getNodeReadCount(getTwinNode(target), graph);
66
+
67
+ nodeLength = getNodeLength(source);
68
+ for (index = 0; index < targetLength; index++) {
69
+ marker = getShortReadMarkerAtIndex(targetArray, index);
70
+ position = getShortReadMarkerPosition(marker);
71
+ if (position != -1) {
72
+ position += nodeLength;
73
+ setShortReadMarkerPosition(marker, position);
74
+ }
75
+ }
76
+
77
+ // Merging lists
78
+ mergeNodeReads(target, source, graph);
79
+ mergeNodeReads(getTwinNode(target), getTwinNode(source), graph);
80
+ }
81
+
82
+ // Replaces two consecutive nodes into a single equivalent node
83
+ // The extra memory is freed
84
+ void concatenateStringOfNodes(Node * nodeA, Graph * graph)
85
+ {
86
+ Node *twinA = getTwinNode(nodeA);
87
+ Node * nodeB = nodeA;
88
+ Node * twinB;
89
+ Node *currentNode, *nextNode;
90
+ Coordinate totalLength = 0;
91
+ PassageMarkerI marker, tmpMarker;
92
+ Arc *arc;
93
+
94
+ while (simpleArcCount(nodeB) == 1
95
+ &&
96
+ simpleArcCount(getTwinNode
97
+ (getDestination(getArc(nodeB)))) ==
98
+ 1
99
+ && getDestination(getArc(nodeB)) != getTwinNode(nodeB)
100
+ && getDestination(getArc(nodeB)) != nodeA) {
101
+ totalLength += getNodeLength(nodeB);
102
+ nodeB = getDestination(getArc(nodeB));
103
+ }
104
+ twinB = getTwinNode(nodeB);
105
+ totalLength += getNodeLength(nodeB);
106
+ reallocateNodeDescriptor(nodeA, totalLength);
107
+
108
+ currentNode = nodeA;
109
+ while (currentNode != nodeB) {
110
+ currentNode = getDestination(getArc(currentNode));
111
+
112
+ // Passage marker management in node A:
113
+ for (marker = getMarker(nodeA); marker != NULL_IDX;
114
+ marker = getNextInNode(marker)) {
115
+ if (getNode(getNextInSequence(marker)) != currentNode
116
+ || getFinishOffset(marker) != 0
117
+ || getStartOffset(getNextInSequence(marker)) != 0
118
+ || getPassageMarkerFinish(marker) != getPassageMarkerStart(getNextInSequence(marker)))
119
+ incrementFinishOffset(marker,
120
+ getNodeLength(currentNode));
121
+ }
122
+
123
+ // Swapping new born passageMarkers from B to A
124
+ for (marker = getMarker(currentNode); marker != NULL_IDX; marker = tmpMarker) {
125
+ tmpMarker = getNextInNode(marker);
126
+
127
+ if (isLocallyInitial(marker)
128
+ || getNode(getPreviousInSequence(marker)) != nodeA
129
+ || getStartOffset(marker) != 0
130
+ || getFinishOffset(getPreviousInSequence(marker)) != 0
131
+ || getPassageMarkerStart(marker) != getPassageMarkerFinish(getPreviousInSequence(marker))) {
132
+ extractPassageMarker(marker);
133
+ incrementFinishOffset(getTwinMarker(marker),
134
+ getNodeLength(nodeA));
135
+ transposePassageMarker(marker, nodeA);
136
+ } else
137
+ disconnectNextPassageMarker(getPreviousInSequence
138
+ (marker), graph);
139
+ }
140
+
141
+ // Read starts
142
+ concatenateReadStarts(nodeA, currentNode, graph);
143
+
144
+ // Gaps
145
+ appendNodeGaps(nodeA, currentNode, graph);
146
+
147
+ // Update uniqueness:
148
+ setUniqueness(nodeA, getUniqueness(nodeA) || getUniqueness(currentNode));
149
+
150
+ #ifndef SINGLE_COV_CAT
151
+ Category cat;
152
+ for (cat = 0; cat < CATEGORIES; cat++) {
153
+ // Update virtual coverage
154
+ incrementVirtualCoverage(nodeA, cat,
155
+ getVirtualCoverage(currentNode, cat));
156
+ // Update original virtual coverage
157
+ incrementOriginalVirtualCoverage(nodeA, cat,
158
+ getOriginalVirtualCoverage(currentNode, cat));
159
+ }
160
+ #else
161
+ // Update virtual coverage
162
+ incrementVirtualCoverage(nodeA, getVirtualCoverage(currentNode));
163
+ #endif
164
+
165
+ // Descriptor management (node)
166
+ directlyAppendDescriptors(nodeA, currentNode, totalLength);
167
+ }
168
+
169
+ // Correct arcs
170
+ for (arc = getArc(nodeB); arc != NULL; arc = getNextArc(arc)) {
171
+ if (getDestination(arc) != twinB)
172
+ createAnalogousArc(nodeA, getDestination(arc),
173
+ arc, graph);
174
+ else
175
+ createAnalogousArc(nodeA, twinA, arc, graph);
176
+ }
177
+
178
+ // Freeing gobbled nodes
179
+ currentNode = getTwinNode(nodeB);
180
+ while (currentNode != getTwinNode(nodeA)) {
181
+ arc = getArc(currentNode);
182
+ nextNode = getDestination(arc);
183
+ destroyNode(currentNode, graph);
184
+ currentNode = nextNode;
185
+ }
186
+ }
187
+
188
+ // Detects sequences that could be simplified through concatentation
189
+ // Iterates till graph cannot be more simplified
190
+ // Useless nodes are freed from memory and remaining ones are renumbered
191
+ void concatenateGraph(Graph * graph)
192
+ {
193
+ IDnum nodeIndex;
194
+ Node *node, *twin;
195
+
196
+ velvetLog("Concatenation...\n");
197
+
198
+ for (nodeIndex = 1; nodeIndex < nodeCount(graph); nodeIndex++) {
199
+ node = getNodeInGraph(graph, nodeIndex);
200
+
201
+ if (node == NULL)
202
+ continue;
203
+
204
+ twin = getTwinNode(node);
205
+ while (simpleArcCount(node) == 1
206
+ &&
207
+ simpleArcCount(getTwinNode
208
+ (getDestination(getArc(node)))) ==
209
+ 1) {
210
+ if (getDestination(getArc(node)) == twin
211
+ || getDestination(getArc(node)) == node)
212
+ break;
213
+ concatenateStringOfNodes(node,
214
+ graph);
215
+ }
216
+
217
+ while (simpleArcCount(twin) == 1
218
+ &&
219
+ simpleArcCount(getTwinNode
220
+ (getDestination(getArc(twin)))) ==
221
+ 1) {
222
+ if (getDestination(getArc(twin)) == node
223
+ || getDestination(getArc(twin)) == twin)
224
+ break;
225
+ concatenateStringOfNodes(twin,
226
+ graph);
227
+ }
228
+ }
229
+
230
+ renumberNodes(graph);
231
+ sortGapMarkers(graph);
232
+ velvetLog("Concatenation over!\n");
233
+ }
@@ -0,0 +1,30 @@
1
+ /*
2
+ Copyright 2007, 2008 Daniel Zerbino (zerbino@ebi.ac.uk)
3
+
4
+ This file is part of Velvet.
5
+
6
+ Velvet is free software; you can redistribute it and/or modify
7
+ it under the terms of the GNU General Public License as published by
8
+ the Free Software Foundation; either version 2 of the License, or
9
+ (at your option) any later version.
10
+
11
+ Velvet is distributed in the hope that it will be useful,
12
+ but WITHOUT ANY WARRANTY; without even the implied warranty of
13
+ MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
14
+ GNU General Public License for more details.
15
+
16
+ You should have received a copy of the GNU General Public License
17
+ along with Velvet; if not, write to the Free Software
18
+ Foundation, Inc., 51 Franklin St, Fifth Floor, Boston, MA 02110-1301 USA
19
+
20
+ */
21
+ #ifndef _CONCATENATEDGRAPH_H_
22
+ #define _CONCATENATEDGRAPH_H_
23
+
24
+ // Concatenates short read markers from node B to the end of nodeA
25
+ void concatenateReadStarts(Node * nodeA, Node * nodeB, Graph * graph);
26
+
27
+ // Concatenates all pairs of nodes which form a linear structure
28
+ void concatenateGraph(Graph * graph);
29
+
30
+ #endif
@@ -0,0 +1,262 @@
1
+ /*
2
+ Copyright 2007, 2008 Daniel Zerbino (zerbino@ebi.ac.uk)
3
+
4
+ This file is part of Velvet.
5
+
6
+ Velvet is free software; you can redistribute it and/or modify
7
+ it under the terms of the GNU General Public License as published by
8
+ the Free Software Foundation; either version 2 of the License, or
9
+ (at your option) any later version.
10
+
11
+ Velvet is distributed in the hope that it will be useful,
12
+ but WITHOUT ANY WARRANTY; without even the implied warranty of
13
+ MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
14
+ GNU General Public License for more details.
15
+
16
+ You should have received a copy of the GNU General Public License
17
+ along with Velvet; if not, write to the Free Software
18
+ Foundation, Inc., 51 Franklin St, Fifth Floor, Boston, MA 02110-1301 USA
19
+
20
+ */
21
+ #include <stdlib.h>
22
+ #include <stdio.h>
23
+
24
+ #include "globals.h"
25
+ #include "preGraph.h"
26
+ #include "utility.h"
27
+
28
+ // Replaces two consecutive preNodes into a single equivalent preNode
29
+ // The extra memory is freed
30
+ static void concatenatePreNodes(IDnum preNodeAID, PreArcI oldPreArc,
31
+ PreGraph * preGraph)
32
+ {
33
+ IDnum preNodeBID = preNodeAID;
34
+ IDnum currentPreNodeID, nextPreNodeID;
35
+ PreArcI preArc = oldPreArc;
36
+ Coordinate totalLength = 0;
37
+ Coordinate arrayLength;
38
+ Descriptor * descr, * ptr;
39
+ int writeOffset = 0;
40
+ int wordLength = getWordLength_pg(preGraph);
41
+ Coordinate totalOffset = 0;
42
+
43
+ //velvetLog("Concatenating nodes %li and %li\n", preNodeAID, preNodeBID);
44
+
45
+ while(hasSinglePreArc_pg(preNodeBID, preGraph)
46
+ &&
47
+ hasSinglePreArc_pg(getOtherEnd_pg
48
+ (preArc, preNodeBID),
49
+ preGraph)
50
+ && !isLoop_pg(preArc)
51
+ && getDestination_pg(preArc, preNodeBID) != preNodeAID) {
52
+
53
+ totalLength += getPreNodeLength_pg(preNodeBID, preGraph);
54
+ preNodeBID = getDestination_pg(preArc, preNodeBID);
55
+ preArc = getPreArc_pg(preNodeBID, preGraph);
56
+ }
57
+ totalLength += getPreNodeLength_pg(preNodeBID, preGraph);
58
+ totalLength += wordLength - 1;
59
+
60
+ // Reference marker management
61
+ if (referenceMarkersAreActivated_pg(preGraph)) {
62
+ currentPreNodeID = preNodeAID;
63
+ preArc = getPreArc_pg(currentPreNodeID, preGraph);
64
+ for (currentPreNodeID = getDestination_pg(preArc, currentPreNodeID); currentPreNodeID != preNodeBID; currentPreNodeID = getDestination_pg(preArc, currentPreNodeID)) {
65
+ concatenateReferenceMarkers_pg(preNodeAID, currentPreNodeID, preGraph, totalOffset);
66
+ preArc = getPreArc_pg(currentPreNodeID, preGraph);
67
+ totalOffset += getPreNodeLength_pg(currentPreNodeID, preGraph);
68
+ }
69
+ concatenateReferenceMarkers_pg(preNodeAID, currentPreNodeID, preGraph, totalOffset);
70
+ }
71
+
72
+ // Descriptor management (preNode)
73
+ arrayLength = totalLength / 4;
74
+ if (totalLength % 4)
75
+ arrayLength++;
76
+ descr = callocOrExit(arrayLength, Descriptor);
77
+ ptr = descr;
78
+ if (preNodeAID > 0) {
79
+ currentPreNodeID = preNodeAID;
80
+ appendDescriptors_pg(&ptr, &writeOffset, currentPreNodeID, preGraph, true);
81
+ preArc = getPreArc_pg(currentPreNodeID, preGraph);
82
+ currentPreNodeID = getDestination_pg(preArc, currentPreNodeID);
83
+ while (currentPreNodeID != preNodeBID) {
84
+ appendDescriptors_pg(&ptr, &writeOffset, currentPreNodeID, preGraph, false);
85
+ preArc = getPreArc_pg(currentPreNodeID, preGraph);
86
+ currentPreNodeID = getDestination_pg(preArc, currentPreNodeID);
87
+ }
88
+ appendDescriptors_pg(&ptr, &writeOffset, currentPreNodeID, preGraph, false);
89
+ } else {
90
+ currentPreNodeID = -preNodeBID;
91
+ appendDescriptors_pg(&ptr, &writeOffset ,currentPreNodeID, preGraph, true);
92
+ preArc = getPreArc_pg(currentPreNodeID, preGraph);
93
+ currentPreNodeID = getDestination_pg(preArc, currentPreNodeID);
94
+ while (currentPreNodeID != -preNodeAID) {
95
+ appendDescriptors_pg(&ptr, &writeOffset ,currentPreNodeID, preGraph, false);
96
+ preArc = getPreArc_pg(currentPreNodeID, preGraph);
97
+ currentPreNodeID = getDestination_pg(preArc, currentPreNodeID);
98
+ }
99
+ appendDescriptors_pg(&ptr, &writeOffset ,currentPreNodeID, preGraph, false);
100
+ }
101
+
102
+ if (writeOffset != 0)
103
+ while (writeOffset++ != 4)
104
+ (*ptr) >>= 2;
105
+
106
+ setPreNodeDescriptor_pg(descr, totalLength - wordLength + 1, preNodeAID, preGraph);
107
+
108
+ // Correct preArcs
109
+ for (preArc = getPreArc_pg(preNodeBID, preGraph); preArc != NULL_IDX;
110
+ preArc = getNextPreArc_pg(preArc, preNodeBID)) {
111
+ if (getDestination_pg(preArc, preNodeBID) != -preNodeBID)
112
+ createAnalogousPreArc_pg(preNodeAID,
113
+ getDestination_pg(preArc,
114
+ preNodeBID),
115
+ preArc, preGraph);
116
+ else
117
+ createAnalogousPreArc_pg(preNodeAID, -preNodeAID,
118
+ preArc, preGraph);
119
+ }
120
+
121
+ // Freeing gobbled preNode
122
+ currentPreNodeID = -preNodeBID;
123
+ while (currentPreNodeID != -preNodeAID) {
124
+ preArc = getPreArc_pg(currentPreNodeID, preGraph);
125
+ nextPreNodeID = getDestination_pg(preArc, currentPreNodeID);
126
+ destroyPreNode_pg(currentPreNodeID, preGraph);
127
+ currentPreNodeID = nextPreNodeID;
128
+ }
129
+ }
130
+
131
+ // Detects sequences that could be simplified through concatentation
132
+ // Iterates till preGraph cannot be more simplified
133
+ // Useless preNodes are freed from memory and remaining ones are renumbered
134
+ void concatenatePreGraph_pg(PreGraph * preGraph)
135
+ {
136
+ IDnum preNodeIndex;
137
+ PreArcI preArc;
138
+ PreNode *preNode;
139
+
140
+ velvetLog("Concatenation...\n");
141
+
142
+ for (preNodeIndex = 1; preNodeIndex < preNodeCount_pg(preGraph);
143
+ preNodeIndex++) {
144
+ preNode = getPreNodeInPreGraph_pg(preGraph, preNodeIndex);
145
+
146
+ if (preNode == NULL)
147
+ continue;
148
+
149
+ preArc = getPreArc_pg(preNodeIndex, preGraph);
150
+
151
+ while (hasSinglePreArc_pg(preNodeIndex, preGraph)
152
+ &&
153
+ hasSinglePreArc_pg(getOtherEnd_pg
154
+ (preArc, preNodeIndex),
155
+ preGraph)) {
156
+ if (isLoop_pg(preArc))
157
+ break;
158
+ concatenatePreNodes(preNodeIndex, preArc,
159
+ preGraph);
160
+ preArc = getPreArc_pg(preNodeIndex, preGraph);
161
+ }
162
+
163
+ preArc = getPreArc_pg(-preNodeIndex, preGraph);
164
+
165
+ while (hasSinglePreArc_pg(-preNodeIndex, preGraph)
166
+ &&
167
+ hasSinglePreArc_pg(getOtherEnd_pg
168
+ (preArc, -preNodeIndex),
169
+ preGraph)) {
170
+ if (isLoop_pg(preArc))
171
+ break;
172
+ concatenatePreNodes(-preNodeIndex, preArc,
173
+ preGraph);
174
+ preArc = getPreArc_pg(-preNodeIndex, preGraph);
175
+ }
176
+ }
177
+
178
+ renumberPreNodes_pg(preGraph);
179
+ velvetLog("Concatenation over!\n");
180
+ }
181
+
182
+ static boolean isEligibleTip(IDnum index, PreGraph * preGraph, Coordinate
183
+ cutoffLength)
184
+ {
185
+ IDnum currentIndex = -index;
186
+ Coordinate totalLength = 0;
187
+ PreArcI activeArc = NULL_IDX;
188
+ PreArcI arc;
189
+ IDnum mult = 0;
190
+
191
+ if (getPreArc_pg(index, preGraph) != NULL_IDX)
192
+ return false;
193
+
194
+ // Finding first tangle
195
+ while (currentIndex != 0
196
+ && simplePreArcCount_pg(-currentIndex, preGraph) < 2
197
+ && simplePreArcCount_pg(currentIndex, preGraph) < 2
198
+ && (!referenceMarkersAreActivated_pg(preGraph) || !hasPreMarkers(currentIndex, preGraph))) {
199
+ totalLength += getPreNodeLength_pg(currentIndex, preGraph);
200
+ activeArc = getPreArc_pg(currentIndex, preGraph);
201
+ currentIndex = getDestination_pg(activeArc, currentIndex);
202
+ }
203
+
204
+ // If too long
205
+ if (totalLength >= cutoffLength)
206
+ return false;
207
+
208
+ // If isolated snippet:
209
+ if (currentIndex == 0)
210
+ return true;
211
+
212
+ // Joined tips
213
+ if (simplePreArcCount_pg(-currentIndex, preGraph) < 2)
214
+ return false;
215
+
216
+ // If unique event
217
+ if (getMultiplicity_pg(activeArc) == 1)
218
+ return true;
219
+
220
+ // Computing max arc
221
+ for (arc = getPreArc_pg(-currentIndex, preGraph); arc != NULL_IDX;
222
+ arc = getNextPreArc_pg(arc, -currentIndex))
223
+ if (getMultiplicity_pg(arc) > mult)
224
+ mult = getMultiplicity_pg(arc);
225
+
226
+ // Testing for minority
227
+ return mult > getMultiplicity_pg(activeArc);
228
+ }
229
+
230
+ void clipTips_pg(PreGraph * preGraph)
231
+ {
232
+ IDnum index;
233
+ PreNode *current;
234
+ boolean modified = true;
235
+ Coordinate cutoffLength = getWordLength_pg(preGraph) * 2;
236
+ IDnum counter = 0;
237
+
238
+ velvetLog("Clipping short tips off preGraph\n");
239
+
240
+ // while (modified) {
241
+ // modified = false;
242
+ // for (index = 1; index <= preNodeCount_pg(preGraph);
243
+ // index++) {
244
+ // current = getPreNodeInPreGraph_pg(preGraph, index);
245
+ //
246
+ // if (current == NULL)
247
+ // continue;
248
+ //
249
+ // if (isEligibleTip(index, preGraph, cutoffLength)
250
+ // || isEligibleTip(-index, preGraph,
251
+ // cutoffLength)) {
252
+ // counter++;
253
+ // destroyPreNode_pg(index, preGraph);
254
+ // modified = true;
255
+ // }
256
+ // }
257
+ // }
258
+
259
+ concatenatePreGraph_pg(preGraph);
260
+ velvetLog("%li tips cut off\n", (long) counter);
261
+ velvetLog("%li nodes left\n", (long) preNodeCount_pg(preGraph));
262
+ }