genome-spy-python 0.1.0__py3-none-any.whl

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (64) hide show
  1. genome_spy/__init__.py +199 -0
  2. genome_spy/_chart_authoring.py +231 -0
  3. genome_spy/_conditions.py +72 -0
  4. genome_spy/_embed.py +87 -0
  5. genome_spy/_expressions.py +271 -0
  6. genome_spy/_parameters.py +267 -0
  7. genome_spy/_render.py +207 -0
  8. genome_spy/_utils.py +75 -0
  9. genome_spy/_widget.py +262 -0
  10. genome_spy/api.py +198 -0
  11. genome_spy/arrow.py +155 -0
  12. genome_spy/channels.py +193 -0
  13. genome_spy/chart.py +1240 -0
  14. genome_spy/data.py +56 -0
  15. genome_spy/data_transformers.py +267 -0
  16. genome_spy/datasets/__init__.py +189 -0
  17. genome_spy/datasets/_airway.py +219 -0
  18. genome_spy/datasets/_annotations.py +37 -0
  19. genome_spy/datasets/_gistic.py +43 -0
  20. genome_spy/datasets/_grammar.py +66 -0
  21. genome_spy/datasets/_hapmap.py +180 -0
  22. genome_spy/datasets/_mutation.py +289 -0
  23. genome_spy/datasets/_oncoprint.py +523 -0
  24. genome_spy/datasets/data/airway_metadata.csv +9 -0
  25. genome_spy/datasets/data/airway_scaledcounts.csv +38695 -0
  26. genome_spy/datasets/data/brca.maf.gz +0 -0
  27. genome_spy/datasets/data/hapmap_gwas.csv +14413 -0
  28. genome_spy/datasets/data/mutation_impact_reference.json +27 -0
  29. genome_spy/datasets/data/oncoprint_dataset3.json +266 -0
  30. genome_spy/datasets/data/p53_sequence_comparison.json.gz +0 -0
  31. genome_spy/datasets/data/pik3ca_mutations.json +1 -0
  32. genome_spy/datasets/data/pik3ca_tcga_brca_lollipop.json +38 -0
  33. genome_spy/datasets/data/refseq_gene_bodies.csv.gz +0 -0
  34. genome_spy/datasets/data/tal1_alphagenome_reference.json.gz +0 -0
  35. genome_spy/datasets/data/tcga.tsv +146 -0
  36. genome_spy/datasets/data/tcga_laml.maf.gz +0 -0
  37. genome_spy/datasets/data/tcga_laml_annot.tsv +201 -0
  38. genome_spy/datasets/data/tcga_laml_combined_oncoplot.json.gz +0 -0
  39. genome_spy/datasets/data/tcga_ov_gistic_lesions.tsv.gz +0 -0
  40. genome_spy/datasets/data/tcga_ov_gistic_scores.tsv.gz +0 -0
  41. genome_spy/helpers.py +185 -0
  42. genome_spy/jupyter.py +5 -0
  43. genome_spy/py.typed +0 -0
  44. genome_spy/schema/__init__.py +784 -0
  45. genome_spy/schema/_kwds.py +1394 -0
  46. genome_spy/schema/_typing.py +186 -0
  47. genome_spy/schema/capabilities.json +593 -0
  48. genome_spy/schema/channels.py +8943 -0
  49. genome_spy/schema/composition.py +1064 -0
  50. genome_spy/schema/core.py +51821 -0
  51. genome_spy/schema/ergonomics.py +2056 -0
  52. genome_spy/schema/expressions.py +476 -0
  53. genome_spy/schema/genome-spy-schema.json +33657 -0
  54. genome_spy/schema/lazy.py +326 -0
  55. genome_spy/schema/mixins.py +11684 -0
  56. genome_spy/schemapi.py +264 -0
  57. genome_spy/static/widget.js +345 -0
  58. genome_spy_python-0.1.0.dist-info/METADATA +185 -0
  59. genome_spy_python-0.1.0.dist-info/RECORD +64 -0
  60. genome_spy_python-0.1.0.dist-info/WHEEL +4 -0
  61. genome_spy_python-0.1.0.dist-info/licenses/LICENSE +21 -0
  62. genome_spy_python-0.1.0.dist-info/licenses/LICENSES/ALTAIR-BSD-3-Clause.txt +27 -0
  63. genome_spy_python-0.1.0.dist-info/licenses/LICENSES/GALLERY-DATA-MIT.txt +22 -0
  64. genome_spy_python-0.1.0.dist-info/licenses/THIRD_PARTY_NOTICES.md +42 -0
genome_spy/datasets/data/tcga.tsv ADDED
@@ -0,0 +1,146 @@
1
+ track_name track_type TCGA-75-5122 TCGA-91-6836 TCGA-55-7576 TCGA-MN-A4N5 TCGA-05-4250 TCGA-44-7661 TCGA-55-8094 TCGA-55-7910 TCGA-99-8028 TCGA-55-7283 TCGA-05-4433 TCGA-44-7672 TCGA-50-5941 TCGA-50-8459 TCGA-55-7815 TCGA-67-3774 TCGA-MP-A4TF TCGA-MP-A4TK TCGA-44-A479 TCGA-55-8092 TCGA-49-AAR9 TCGA-69-8255 TCGA-55-8507 TCGA-73-4668 TCGA-91-6835 TCGA-49-6745 TCGA-55-1592 TCGA-86-7954 TCGA-95-8494 TCGA-NJ-A55R TCGA-44-6145 TCGA-55-8090 TCGA-78-7539 TCGA-95-7039 TCGA-05-4249 TCGA-05-4427 TCGA-05-4417 TCGA-86-8359 TCGA-95-7567 TCGA-MP-A4TI TCGA-86-A4JF TCGA-86-8056 TCGA-64-5815 TCGA-44-8117 TCGA-05-4415 TCGA-86-7713 TCGA-99-8032 TCGA-35-3615 TCGA-64-5774 TCGA-69-8253 TCGA-55-8616 TCGA-55-8302 TCGA-67-4679 TCGA-64-5778 TCGA-44-6776 TCGA-55-7284 TCGA-NJ-A4YI TCGA-91-6849 TCGA-69-7980 TCGA-55-8508 TCGA-49-4506 TCGA-50-5936 TCGA-55-7907 TCGA-86-8054 TCGA-49-AARO TCGA-55-A490 TCGA-J2-A4AG TCGA-05-4390 TCGA-05-4405 TCGA-55-8299 TCGA-95-A4VK TCGA-05-4418 TCGA-55-8097 TCGA-93-7347 TCGA-64-1677 TCGA-55-7281 TCGA-55-7726 TCGA-73-4670 TCGA-86-7953 TCGA-93-A4JO TCGA-91-6828 TCGA-69-8254 TCGA-44-A47F TCGA-44-3917 TCGA-55-8203 TCGA-69-7978 TCGA-73-4677 TCGA-MP-A4T7 TCGA-78-7160 TCGA-78-7161 TCGA-NJ-A4YP TCGA-4B-A93V TCGA-05-4244 TCGA-05-4395 TCGA-05-4403 TCGA-44-A47A TCGA-44-6144 TCGA-44-6146 TCGA-44-7659 TCGA-44-7671 TCGA-49-AARQ TCGA-49-4505 TCGA-49-4510 TCGA-50-5051 TCGA-50-5932 TCGA-50-5933 TCGA-50-7109 TCGA-53-7813 TCGA-55-A494 TCGA-55-1595 TCGA-55-6642 TCGA-55-6970 TCGA-55-6975 TCGA-55-6983 TCGA-55-6984 TCGA-55-7725 TCGA-55-7728 TCGA-55-7911 TCGA-55-7914 TCGA-55-8207 TCGA-55-8512 TCGA-55-8514 TCGA-55-8615 TCGA-62-A46R TCGA-62-A46S TCGA-62-8398 TCGA-64-5775 TCGA-67-3773 TCGA-69-7973 TCGA-69-7974 TCGA-73-4662 TCGA-73-7498 TCGA-J2-8194 TCGA-75-5126 TCGA-75-6206 TCGA-75-7027 TCGA-75-7030 TCGA-L9-A443 TCGA-MP-A4SY TCGA-MP-A4T4 TCGA-MP-A4T8 TCGA-MP-A4TD TCGA-MP-A4TE TCGA-78-7145 TCGA-78-7148 TCGA-78-7166 TCGA-78-7167 TCGA-78-7540 TCGA-78-8655 TCGA-NJ-A4YG TCGA-NJ-A55O TCGA-80-5608 TCGA-83-5908 TCGA-86-A456 TCGA-86-8076 TCGA-86-8674 TCGA-93-8067 TCGA-95-A4VN TCGA-95-A4VP TCGA-95-7562 TCGA-97-A4M0 TCGA-97-A4M5 TCGA-97-7554 TCGA-97-7938 TCGA-97-7941 TCGA-97-8176 TCGA-97-8179 TCGA-99-8025 TCGA-99-8033 TCGA-55-8505 TCGA-62-8399 TCGA-62-A46O TCGA-91-6840 TCGA-05-4420 TCGA-49-AAR4 TCGA-78-7154 TCGA-55-6981 TCGA-62-A46P TCGA-78-8660 TCGA-69-7765 TCGA-44-2662 TCGA-MN-A4N1 TCGA-50-5930 TCGA-55-8511 TCGA-55-6968 TCGA-53-A4EZ TCGA-55-6979 TCGA-49-AARN TCGA-75-5146 TCGA-44-6774 TCGA-05-5428 TCGA-05-4389 TCGA-55-7903 TCGA-55-7913 TCGA-05-4410 TCGA-44-2666 TCGA-50-5044 TCGA-50-5942 TCGA-50-5946 TCGA-50-6594 TCGA-62-A46V TCGA-62-A472 TCGA-78-7153 TCGA-78-7537 TCGA-78-7633 TCGA-78-8662 TCGA-80-5607 TCGA-86-7714 TCGA-91-A4BD TCGA-97-A4M7 TCGA-44-3918 TCGA-73-A9RS TCGA-55-8506 TCGA-05-4382 TCGA-L4-A4E6 TCGA-L9-A8F4 TCGA-97-7546 TCGA-J2-8192 TCGA-78-7220 TCGA-55-8620 TCGA-44-6777 TCGA-62-8394 TCGA-50-6592 TCGA-35-4123 TCGA-67-3771 TCGA-38-4631 TCGA-78-7146 TCGA-50-5944 TCGA-64-1680 TCGA-86-8672 TCGA-55-8087 TCGA-55-A4DF TCGA-86-8073 TCGA-05-4434 TCGA-71-6725 TCGA-86-8358 TCGA-44-3396 TCGA-53-7624 TCGA-38-4626 TCGA-49-4486 TCGA-75-5125 TCGA-97-8177 TCGA-49-4488 TCGA-38-4625 TCGA-49-6744 TCGA-78-7536 TCGA-35-4122 TCGA-91-7771 TCGA-64-1676 TCGA-05-5425 TCGA-75-6211 TCGA-44-6778 TCGA-91-A4BC TCGA-50-6591 TCGA-53-7626 TCGA-44-A47B TCGA-67-6215 TCGA-75-7031 TCGA-69-7979 TCGA-44-2656 TCGA-49-6761 TCGA-55-A493 TCGA-55-7727 TCGA-97-A4LX TCGA-78-7535 TCGA-55-A48Z TCGA-50-5049 TCGA-L9-A50W TCGA-97-8547 TCGA-86-7701 TCGA-55-6985 TCGA-49-AARE TCGA-86-7955 TCGA-44-5644 TCGA-95-7043 TCGA-05-4396 TCGA-78-7149 TCGA-69-A59K TCGA-86-8673 TCGA-78-7155 TCGA-55-8510 TCGA-64-1679 TCGA-MN-A4N4 TCGA-49-AAR0 TCGA-49-4490 TCGA-MP-A4SW TCGA-91-6848 TCGA-91-6829 TCGA-86-7711 TCGA-55-6972 TCGA-55-6971 TCGA-73-7499 TCGA-64-1681 TCGA-05-4402 TCGA-55-7573 TCGA-91-6847 TCGA-50-6673 TCGA-05-4430 TCGA-44-8119 TCGA-55-1594 TCGA-97-8174 TCGA-05-4426 TCGA-78-8640 TCGA-38-7271 TCGA-NJ-A4YQ TCGA-05-4398 TCGA-44-3398 TCGA-44-7662 TCGA-55-6712 TCGA-55-8089 TCGA-05-4424 TCGA-38-4628 TCGA-86-8074 TCGA-44-7660 TCGA-50-5045 TCGA-55-A4DG TCGA-55-8204 TCGA-55-8614 TCGA-62-A471 TCGA-62-8395 TCGA-62-8402 TCGA-69-7764 TCGA-J2-A4AD TCGA-L4-A4E5 TCGA-L9-A7SV TCGA-MP-A4TC TCGA-86-6851 TCGA-44-A4SS TCGA-44-8120 TCGA-55-6969 TCGA-91-6830 TCGA-05-4422 TCGA-49-4487 TCGA-49-4507 TCGA-50-5935 TCGA-55-8208 TCGA-62-A46U TCGA-73-4676 TCGA-MP-A4SV TCGA-80-5611 TCGA-86-6562 TCGA-44-7670 TCGA-95-7947 TCGA-05-4384 TCGA-05-4397 TCGA-05-4425 TCGA-05-4432 TCGA-05-5423 TCGA-05-5429 TCGA-05-5715 TCGA-35-5375 TCGA-38-A44F TCGA-38-4627 TCGA-38-4632 TCGA-38-6178 TCGA-44-A4SU TCGA-44-A47G TCGA-44-2655 TCGA-44-2657 TCGA-44-2659 TCGA-44-2665 TCGA-44-2668 TCGA-44-3919 TCGA-44-4112 TCGA-44-5643 TCGA-44-5645 TCGA-44-6148 TCGA-44-6775 TCGA-44-6779 TCGA-44-7667 TCGA-44-7669 TCGA-49-AAQV TCGA-49-AAR2 TCGA-49-AAR3 TCGA-49-AARR TCGA-49-4494 TCGA-49-4501 TCGA-49-4512 TCGA-49-4514 TCGA-49-6742 TCGA-49-6743 TCGA-49-6767 TCGA-50-5055 TCGA-50-5066 TCGA-50-5068 TCGA-50-5072 TCGA-50-5931 TCGA-50-5939 TCGA-50-6590 TCGA-50-6593 TCGA-50-6595 TCGA-50-6597 TCGA-50-8457 TCGA-50-8460 TCGA-55-A48X TCGA-55-A48Y TCGA-55-A57B TCGA-55-A491 TCGA-55-A492 TCGA-55-1596 TCGA-55-5899 TCGA-55-6543 TCGA-55-6978 TCGA-55-6980 TCGA-55-6982 TCGA-55-6986 TCGA-55-6987 TCGA-55-7570 TCGA-55-7574 TCGA-55-7724 TCGA-55-7994 TCGA-55-7995 TCGA-55-8085 TCGA-55-8091 TCGA-55-8096 TCGA-55-8205 TCGA-55-8206 TCGA-55-8301 TCGA-55-8513 TCGA-55-8619 TCGA-55-8621 TCGA-62-A46Y TCGA-62-A470 TCGA-62-8397 TCGA-64-5779 TCGA-64-5781 TCGA-67-3770 TCGA-67-3772 TCGA-67-6216 TCGA-67-6217 TCGA-69-7760 TCGA-69-7761 TCGA-69-7763 TCGA-73-4658 TCGA-73-4659 TCGA-73-4666 TCGA-73-4675 TCGA-J2-A4AE TCGA-75-5147 TCGA-75-6203 TCGA-75-6205 TCGA-75-6207 TCGA-75-6212 TCGA-75-6214 TCGA-75-7025 TCGA-L9-A5IP TCGA-L9-A444 TCGA-L9-A743 TCGA-MP-A4T2 TCGA-MP-A4T6 TCGA-MP-A4T9 TCGA-MP-A4TA TCGA-MP-A4TH TCGA-MP-A4TJ TCGA-MP-A5C7 TCGA-78-7147 TCGA-78-7150 TCGA-78-7152 TCGA-78-7156 TCGA-78-7158 TCGA-78-7159 TCGA-78-7162 TCGA-78-7163 TCGA-78-7542 TCGA-78-8648 TCGA-NJ-A4YF TCGA-NJ-A7XG TCGA-NJ-A55A TCGA-O1-A52J TCGA-S2-AA1A TCGA-86-A4P7 TCGA-86-A4P8 TCGA-86-8055 TCGA-86-8075 TCGA-86-8278 TCGA-86-8279 TCGA-86-8280 TCGA-86-8281 TCGA-86-8585 TCGA-86-8668 TCGA-86-8669 TCGA-86-8671 TCGA-91-6831 TCGA-91-8496 TCGA-91-8497 TCGA-91-8499 TCGA-93-A4JN TCGA-93-A4JP TCGA-93-A4JQ TCGA-93-7348 TCGA-95-7944 TCGA-95-7948 TCGA-95-8039 TCGA-97-A4M1 TCGA-97-A4M2 TCGA-97-A4M3 TCGA-97-A4M6 TCGA-97-7547 TCGA-97-7552 TCGA-97-7553 TCGA-97-7937 TCGA-97-8171 TCGA-97-8172 TCGA-97-8175 TCGA-97-8552 TCGA-99-AA5R TCGA-99-7458
2
+ Mutation spectrum (C>A) CLINICAL 35 250 152 197 127 125 195 138 221 62 4 76 150 32 49 38 184 140 151 179 293 87 433 240 26 14 159 66 14 106 167 28 104 600 128 444 155 61 216 51 226 61 78 345 99 73 169 33 64 59 249 296 123 224 94 3 197 56 300 71 40 24 528 89 328 633 33 263 159 89 105 96 34 44 49 208 15 140 11 8 124 18 23 91 200 218 115 63 19 76 120 58 84 84 36 41 87 9 59 73 321 89 26 39 39 221 105 61 94 148 62 87 30 39 16 51 40 97 56 111 10 111 33 57 29 26 230 47 126 233 92 34 47 251 35 107 3 117 47 177 38 22 42 89 88 86 35 206 39 42 67 265 77 152 11 131 69 225 46 204 154 17 206 175 33 36 75 145 67 2 160 335 39 120 261 51 158 131 74 278 37 184 577 220 106 210 446 176 91 165 144 52 43 147 482 3 13 19 238 249 7 11 24 51 89 460 15 22 1 146 486 430 617 850 5 325 126 11 345 194 145 26 87 127 298 357 144 13 7 99 6 139 728 4 8 447 40 318 135 26 45 4 138 280 116 305 91 61 295 255 181 174 215 9 879 12 5 59 752 419 154 83 70 79 59 13 380 6 9 273 238 613 105 464 555 1147 33 222 173 682 134 264 574 36 8 9 237 236 63 86 154 13 10 11 17 19 40 136 257 42 62 5 252 32 528 275 59 247 29 439 313 30 13 102 174 312 50 53 9 10 8 29 71 153 833 109 424 178 270 206 43 7 155 59 9 81 7 22 96 40 10 501 135 48 275 5 245 55 3 11 144 4 5 212 18 53 17 94 196 211 6 147 9 195 36 5 1 14 32 192 178 8 190 44 1 90 7 8 110 52 234 201 2 102 23 59 116 11 358 121 18 4 13 5 183 24 6 146 110 60 166 3 28 15 34 7 88 132 74 55 673 257 62 7 52 154 5 107 0 2 22 8 31 6 163 480 90 10 6 77 14 8 21 112 93 164 14 8 5 1 5 11 4 252 5 129 263 36 14 9 9 117 37 29 18 89 91 57 102 130 152 19 29 162 4 285 8 45 68 54 10 6 5 6 227 5 92 212 5 36 7 95 2 8 95 12 11 13 32 25 12 15 4 6 93 4 52 10 11 221 10 95 7 1 25 213
3
+ Mutation spectrum (C>G) CLINICAL 23 46 50 50 44 48 36 36 41 33 3 15 62 7 18 12 38 37 28 58 61 43 119 55 13 38 74 27 17 24 25 6 136 126 28 119 27 11 43 47 88 60 12 76 12 14 51 18 13 21 38 61 30 42 18 1 37 17 139 14 12 23 172 21 53 144 8 51 41 20 25 21 7 13 50 51 43 25 6 14 39 5 9 36 41 121 26 15 8 19 115 11 24 35 12 57 26 2 13 27 81 13 8 16 4 53 29 12 25 38 13 16 11 7 2 9 7 25 21 32 5 25 10 19 9 7 43 2 22 60 23 12 12 102 15 21 1 22 22 42 6 8 18 22 24 17 18 2 8 22 12 19 53 33 13 35 157 55 10 41 42 41 35 51 11 23 20 82 20 8 112 126 37 26 73 49 8 28 31 55 64 52 96 64 162 59 45 28 15 27 57 47 16 36 137 5 53 6 101 58 6 5 18 18 13 126 36 4 0 23 107 114 110 175 2 91 26 9 84 53 44 29 51 28 208 80 58 6 12 46 1 215 131 5 4 110 45 116 27 49 32 4 22 69 28 64 41 28 54 62 33 38 41 8 48 3 5 28 156 85 34 36 36 15 18 3 89 3 6 19 45 144 42 97 108 37 34 41 50 171 35 63 237 20 11 8 104 80 41 47 7 17 16 44 5 10 4 26 64 36 25 4 112 28 87 89 31 74 39 222 86 20 8 60 27 84 45 39 27 14 8 9 91 21 148 32 118 66 66 54 84 6 66 29 24 82 7 8 64 27 12 134 105 9 126 4 55 17 4 34 60 0 1 51 10 15 16 14 46 38 5 54 12 56 19 0 1 8 9 52 49 19 32 18 0 20 2 4 58 56 111 57 3 39 8 13 38 14 147 37 22 9 8 1 33 113 4 49 21 23 64 2 4 2 79 1 44 75 73 36 173 102 49 0 23 112 2 38 0 1 7 2 11 1 49 144 24 10 6 15 5 3 3 58 21 41 7 9 8 0 11 11 0 124 1 25 54 27 15 9 5 38 11 8 4 52 75 38 57 25 30 15 3 25 1 69 3 7 17 8 13 7 7 34 45 7 33 99 1 13 6 39 5 2 50 12 8 31 13 84 55 13 6 6 24 1 27 2 3 47 1 19 1 3 5 45
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+ Mutation spectrum (C>T) CLINICAL 36 88 89 63 62 49 63 56 51 75 20 25 56 18 30 28 70 67 45 157 77 67 142 76 14 63 109 57 47 47 36 18 126 187 66 153 32 28 224 86 454 101 31 99 38 28 56 31 20 25 79 110 45 64 35 24 68 18 142 37 29 34 186 37 55 168 21 77 63 41 45 58 33 20 56 81 36 61 17 16 51 24 36 48 59 104 42 22 8 32 179 25 37 71 45 71 37 17 27 42 120 41 7 21 12 101 48 29 45 38 17 41 19 30 7 23 23 36 40 54 8 47 21 50 43 19 59 24 41 92 40 27 43 119 17 36 9 31 46 59 29 22 35 34 42 37 33 15 22 46 20 21 50 66 29 51 189 65 25 58 60 74 72 63 29 52 21 132 42 11 115 166 37 44 101 73 24 35 56 91 57 71 124 110 143 90 20 155 21 29 99 65 44 66 171 16 42 13 111 81 24 16 40 26 22 160 49 14 8 36 132 112 444 232 2 101 47 28 150 86 81 36 55 41 228 86 78 24 23 64 19 256 193 20 31 161 64 151 23 47 48 13 39 106 36 89 71 47 74 100 60 58 65 23 45 16 18 41 200 114 59 71 81 20 24 18 87 10 30 31 61 183 51 134 167 49 49 86 90 186 41 74 291 30 20 28 94 109 42 101 20 24 26 42 13 18 18 39 109 53 39 23 127 15 132 122 39 101 40 260 118 35 17 55 32 90 65 55 41 29 18 22 65 59 164 39 101 81 81 54 85 15 48 47 44 100 19 20 74 57 20 168 141 30 157 20 88 36 22 45 71 6 15 87 24 33 20 21 54 65 18 49 20 84 37 15 2 21 33 82 80 30 56 24 1 33 22 19 78 83 175 61 10 46 31 36 50 28 146 56 40 28 15 14 76 154 18 54 52 36 83 10 11 5 79 11 51 59 69 54 239 112 77 17 30 99 10 46 5 13 17 8 33 7 56 180 30 25 16 40 21 5 23 106 36 49 15 14 15 6 17 22 10 151 15 42 81 27 27 22 10 65 25 19 17 79 119 50 104 48 50 22 11 61 6 80 8 25 30 20 29 17 24 43 64 20 45 90 14 28 13 44 18 17 79 31 20 30 33 82 67 28 20 7 37 11 41 12 17 81 26 60 13 12 8 72
5
+ Mutation spectrum (T>A) CLINICAL 10 36 28 31 22 30 38 30 41 22 2 15 52 5 16 6 31 37 21 45 71 18 73 62 5 3 53 17 6 21 37 9 26 135 37 100 24 22 80 6 90 16 16 67 16 11 44 8 8 12 32 70 35 33 14 4 38 7 50 14 12 7 87 20 58 113 7 54 43 21 20 21 7 12 12 47 6 33 4 6 20 10 3 9 46 49 18 13 4 19 22 11 21 15 11 16 19 2 12 27 55 20 2 8 6 58 19 19 21 37 12 12 8 12 3 12 10 23 14 40 5 31 18 16 12 5 44 8 24 39 18 8 19 49 8 22 0 23 17 36 8 7 14 17 17 24 4 1 7 5 16 19 14 39 3 22 7 41 17 28 42 4 45 32 5 7 13 29 13 1 25 74 1 29 46 5 1 27 26 57 9 37 140 43 25 44 9 77 10 28 21 14 14 33 118 3 5 9 53 41 5 7 12 19 7 131 3 11 3 27 71 85 123 152 0 82 19 3 78 42 32 6 28 18 78 83 34 1 2 14 1 19 148 5 0 121 8 72 26 3 11 4 28 43 19 61 29 13 50 52 34 27 48 1 41 2 7 17 111 67 15 24 14 16 14 3 90 3 1 22 45 116 32 94 80 27 9 50 62 164 29 33 111 16 1 4 43 65 24 13 12 4 4 5 2 4 2 35 65 15 14 3 64 5 125 77 22 54 2 93 70 9 3 42 31 64 7 15 2 1 1 4 12 33 139 19 92 46 55 46 14 4 31 25 3 14 3 12 24 19 4 90 31 11 62 2 67 15 0 1 44 0 3 70 6 13 9 19 37 39 1 36 1 41 7 2 0 3 4 36 45 3 41 16 0 12 4 3 20 7 71 46 1 36 7 18 28 5 90 33 5 1 7 1 42 8 3 41 32 20 33 4 2 1 3 0 11 29 13 25 124 55 16 2 12 43 3 20 0 1 10 0 12 2 18 95 14 3 4 15 6 5 7 19 18 33 4 2 3 2 3 4 0 49 1 34 48 14 8 3 3 45 13 11 2 36 25 9 19 17 37 6 0 37 1 57 2 10 16 12 5 4 2 3 54 3 22 57 6 15 1 24 1 3 16 2 8 8 10 3 2 7 4 5 15 2 17 1 1 32 7 31 2 2 8 44
6
+ Mutation spectrum (T>C) CLINICAL 7 17 27 36 33 11 29 13 26 11 0 14 16 7 8 7 26 14 17 28 22 24 46 32 15 5 61 10 2 16 21 9 24 74 22 68 23 8 191 9 196 10 4 51 11 10 20 6 9 8 14 44 10 29 12 5 25 4 55 13 12 7 47 16 21 60 6 26 29 22 14 28 8 8 14 23 4 38 7 5 15 12 3 11 22 30 16 5 8 14 14 10 16 15 8 14 16 5 16 14 43 12 10 7 4 26 17 15 13 21 8 14 7 9 1 10 4 10 16 21 5 13 8 15 6 7 24 7 14 29 15 6 12 33 4 13 1 21 18 24 15 3 6 12 27 14 6 2 11 11 5 11 9 26 5 15 16 15 9 17 27 4 30 28 5 8 9 26 14 4 31 47 6 17 28 24 7 10 15 33 12 32 45 33 11 26 6 92 15 18 9 19 11 14 58 7 7 6 49 23 6 5 11 5 6 90 5 8 4 18 43 52 113 75 1 58 18 10 37 31 24 7 28 18 68 44 15 5 5 16 3 24 78 2 6 55 11 47 11 8 12 2 22 16 11 43 43 21 32 37 22 36 14 3 21 2 22 16 44 38 10 10 14 16 15 3 59 4 4 16 30 75 28 56 45 11 9 18 28 95 17 19 61 10 6 5 50 58 22 7 5 4 7 10 7 7 8 12 43 10 8 5 52 4 59 52 9 39 10 40 47 6 10 49 13 34 15 26 6 9 3 13 29 18 54 13 60 41 27 34 7 2 17 14 8 30 1 14 19 24 5 41 39 12 71 4 46 14 1 5 34 0 2 45 4 13 8 7 19 15 10 15 4 24 8 11 2 8 6 34 44 4 21 19 0 8 6 3 13 15 60 35 2 24 8 16 27 8 41 25 8 5 6 3 14 8 5 22 24 27 27 2 4 2 7 2 10 29 8 33 94 44 9 4 9 29 2 25 0 2 8 4 9 2 17 55 16 3 3 15 8 3 5 17 11 28 13 5 2 1 7 7 2 37 4 14 20 11 7 11 2 37 11 11 9 26 24 11 13 16 15 6 2 21 1 25 2 6 10 4 3 2 6 4 42 5 21 35 2 13 4 30 1 3 23 9 3 15 9 6 0 8 1 1 16 4 9 5 3 30 5 19 2 1 4 28
7
+ Mutation spectrum (T>G) CLINICAL 3 6 15 9 7 3 17 7 10 2 2 4 14 2 3 1 12 9 5 11 23 15 26 4 4 2 19 6 3 6 5 3 5 30 7 38 9 3 42 6 32 3 2 13 3 6 13 3 1 5 6 7 6 7 4 2 10 1 18 6 5 8 17 8 14 30 1 19 15 2 8 10 5 5 7 7 3 13 3 3 13 2 2 1 8 8 3 5 1 10 7 5 3 7 6 3 8 1 3 5 8 4 1 5 0 18 6 3 7 7 5 1 4 3 0 1 2 12 7 3 0 6 5 3 4 8 9 3 2 12 7 4 2 13 1 5 1 8 6 4 5 3 4 5 4 8 3 0 3 3 0 1 4 3 3 5 5 9 3 2 6 2 9 5 0 6 4 11 4 1 11 17 3 11 9 4 2 10 10 15 4 16 18 18 2 11 4 145 7 3 11 7 3 6 23 3 0 4 9 10 3 3 5 2 2 24 2 2 0 13 13 17 29 24 0 13 9 3 19 10 9 9 8 8 24 14 7 3 2 8 0 16 19 2 1 27 7 14 5 5 3 3 13 13 7 18 11 7 12 11 2 7 8 5 4 1 45 12 23 16 5 6 2 3 12 3 11 5 0 11 8 31 7 25 17 9 0 8 11 40 6 10 23 7 1 4 18 22 4 2 1 2 10 4 1 6 3 4 18 7 4 2 21 2 26 21 6 12 1 24 15 5 8 15 6 14 6 3 3 4 2 2 12 6 23 5 13 17 14 16 4 1 12 4 1 6 1 3 12 11 0 38 10 3 24 2 15 2 1 1 19 1 2 11 0 3 6 3 6 5 2 6 1 12 3 1 0 3 2 17 9 1 9 3 0 4 2 1 3 18 13 12 2 9 4 3 5 4 21 8 3 3 0 4 8 1 0 13 6 7 4 0 3 2 5 0 6 13 6 7 26 19 6 0 3 13 2 5 0 1 3 7 2 2 7 23 6 3 0 8 3 2 2 4 2 15 2 1 3 0 3 2 1 11 2 4 9 1 1 3 1 3 6 3 3 8 16 3 3 3 5 2 2 6 2 9 0 4 5 2 2 5 1 1 10 2 4 14 3 4 3 8 0 2 6 3 2 7 4 3 1 11 3 1 2 3 6 2 0 11 3 6 1 1 2 7
8
+ MSI MANTIS Score CLINICAL 0.2898 0.3153 0.3078 0.3204 0.3059 0.3087 0.3206 0.3415 0.3429 0.3037 0.3053 0.3068 0.292 0.3327 0.337 0.2771 0.3514 0.31 0.3191 0.319 0.3436 0.3363 0.3629 0.2789 0.2993 0.3083 0.2803 0.3267 0.3051 0.3064 0.3023 0.3169 0.3056 0.32 0.2807 0.3043 0.3033 0.3167 0.4503 0.3151 0.5047 0.3353 0.2793 0.3512 0.3033 0.3155 0.3283 0.2804 0.3093 0.3411 0.3503 0.3126 0.2885 0.3135 0.3029 0.3198 0.3335 0.3012 0.3681 0.3292 0.2991 0.3083 0.3314 0.3127 0.3115 0.3394 0.32 0.2876 0.3071 0.329 0.3282 0.2744 0.3278 0.3343 0.2728 0.2873 0.3484 0.2934 0.3435 0.3048 0.299 0.3148 0.3397 0.3142 0.3099 0.3431 0.2761 0.3288 0.2959 0.2989 0.3221 0.3475 0.2886 0.2956 0.2921 0.3226 0.2976 0.3286 0.3019 0.3047 0.3256 0.3359 0.2923 0.3028 0.3033 0.2962 0.3035 0.3387 0.3189 0.2662 0.3046 0.3069 0.2973 0.3045 0.3082 0.3117 0.3474 0.3558 0.3043 0.3312 0.318 0.3151 0.3269 0.3214 0.3163 0.3196 0.2952 0.2811 0.3631 0.3588 0.2984 0.3439 0.313 0.2958 0.2995 0.3008 0.2875 0.3265 0.3095 0.3216 0.3315 0.3054 0.3258 0.296 0.3143 0.3093 0.2999 0.3011 0.3318 0.3188 0.321 0.2893 0.3239 0.3277 0.3188 0.334 0.3262 0.3233 0.3285 0.3409 0.33 0.2956 0.305 0.3584 0.3364 0.3459 0.333 0.3262 0.3357 0.3302 0.3201 0.3242 0.2902 0.291 0.3241 0.3163 0.275 0.3373 0.3233 0.3239 0.2713 0.3314 0.2831 0.3413 0.3192 0.3105 0.2926 0.3164 0.3033 0.2954 0.298 0.2907 0.3455 0.3381 0.3034 0.3003 0.313 0.2881 0.2901 0.3083 0.326 0.3272 0.2986 0.2959 0.3017 0.3528 0.3103 0.3042 0.3219 0.313 0.3106 0.35 0.5316 0.3193 0.3258 0.3245 0.3147 0.3327 0.317 0.3391 0.3033 0.3238 0.2877 0.2877 0.3208 0.3091 0.2965 0.2843 0.2725 0.3472 0.3177 0.3092 0.3277 0.2715 0.3174 0.3391 0.3466 0.317 0.2787 0.278 0.3003 0.3372 0.2967 0.2801 0.2967 0.3287 0.2776 0.3602 0.2746 0.3001 0.2992 0.3067 0.3357 0.3244 0.3176 0.3287 0.2956 0.3033 0.351 0.2996 0.2932 0.3235 0.3554 0.3137 0.3105 0.3062 0.3052 0.3098 0.3431 0.3447 0.3005 0.3338 0.3329 0.3216 0.3486 0.2819 0.3146 0.3272 0.3382 0.3151 0.3384 0.3127 0.3073 0.3252 0.3009 0.3122 0.2978 0.3066 0.3021 0.2864 0.293 0.3566 0.3243 0.2803 0.3036 0.3373 0.2908 0.2825 0.3525 0.2912 0.3258 0.2836 0.323 0.3598 0.32 0.3117 0.281 0.3017 0.3013 0.3445 0.3012 0.3118 0.3273 0.3098 0.305 0.335 0.3441 0.3412 0.3326 0.3261 0.335 0.3472 0.3088 0.3166 0.3574 0.3095 0.3143 0.3039 0.3347 0.2795 0.3068 0.2843 0.295 0.2769 0.3089 0.2956 0.3108 0.3162 0.3118 0.2913 0.2982 0.3216 0.3598 0.285 0.2886 0.3179 0.2759 0.3204 0.3031 0.3207 0.3281 0.3275 0.2806 0.2967 0.2925 0.3233 0.3181 0.2747 0.2817 0.2806 0.3006 0.2747 0.2725 0.2866 0.321 0.3481 0.2964 0.3101 0.2979 0.3057 0.3312 0.3294 0.3355 0.3164 0.3245 0.2794 0.2866 0.307 0.3006 0.3036 0.2849 0.3133 0.3077 0.2919 0.3108 0.2997 0.3013 0.3341 0.2995 0.2839 0.3005 0.3029 0.3402 0.3409 0.3152 0.3259 0.3221 0.3009 0.3293 0.2772 0.3053 0.3 0.279 0.2955 0.2939 0.2868 0.3051 0.3006 0.3064 0.3507 0.3527 0.3538 0.3109 0.3272 0.3506 0.3331 0.345 0.3329 0.3194 0.323 0.3078 0.3295 0.3313 0.3149 0.3101 0.2985 0.2832 0.2699 0.2921 0.2965 0.3473 0.3157 0.3202 0.3074 0.2919 0.2944 0.2958 0.3188 0.2962 0.2893 0.2866 0.2953 0.2999 0.2991 0.296 0.3419 0.3278 0.3215 0.3179 0.3441 0.307 0.3176 0.3143 0.3186 0.3234 0.3081 0.312 0.3139 0.2956 0.3136 0.3248 0.3088 0.3124 0.324 0.3313 0.3395 0.3235 0.3278 0.322 0.3278 0.3312 0.3062 0.3385 0.2979 0.3248 0.341 0.3218 0.3249 0.3245 0.3259 0.3342 0.3378 0.3197 0.3433 0.3523 0.3308 0.3078 0.2995 0.3075 0.3085 0.3321 0.3546 0.3217 0.3065 0.2987 0.306 0.3076 0.3077 0.3059 0.2731 0.3257 0.3261 0.3222 0.3039 0.3635 0.3341 0.2904
9
+ American Joint Committee on Cancer Tumor Stage Code CLINICAL T2 T2 T2A T1A T3 T2A T2B T2B T1A T3 T2 T1B T2A T3 T2A T2 T2B T2 T2 T3 T3 T1A T1A T2 T1 T2A T2 T2 T2A T1B T1 T1A T2B T3 T2 T2 T2 T3 T2B T2A T3 T4 T2 T2A T4 T2B T1A T2 T2 T1A T2A T2 T3 T2 T1 T3 T2 T2 T1B T2A T2 T2 T2A T2B T1A T2B T1B T2 T2 T1B T2B T3 T1A T1A T2 T1B T1B T2 T1B T1A T1A T2B T2B T2 T1B T2B T2A T2 T4 T3 T2A T1B T2 T4 T2 T2A T1A T3 T1B T2A T2 T2 T2 T2 T2 T4 T1 T4 T2A T1 T2 T2 T2 T2 T2 T1A T2A T1A T1B T2A T1A T2A T3 T2 T2 T2 T4 T2 T2A T2A T1 T1B T3 T3 T2 T2 T3 T1A T2 T2 T2 T2 T2B T4 T2 T2 T2 T2 T1 T2 T1B T1 T1 T1A T1 T2A T2A T2A T2B T2A T2A T1B T2A T1A T1B T3 T1A T3 TX T1A T2 T2 T1B T2 T2 T3 T1 T2 T2 T4 T2 T2A T2 T2A T1 T2A T2 T1 T2 T1 T1B T1 T1B T1B T2 T2 T4 T1 T1 T3 T2 T3 T2 T2 T2 T2 T2 T1B T1B T1B T1 T3 T3 T2 T1 T2A T1 T2A T2 T1A T2 T4 T2 T1 T1 T2 T2 T1 T2A T3 T2A T1B T2A T4 T2 T2A T2 T2 T2B T1 T2 T2A T1 T2A T2A T2 T1 T3 T1A T2B T2 T1 T2B T2 T1 T2A T2A T2 T2A T2 T1 T2A T1A T2A T2 T1A T2 T1B T2A T2 T2 T1 T2A T2A T1A T4 T4 T3 T2 T2 T2A T1 T1B T1 T3 T2 T2 T2 T2A T2 T2 T2A T1 T2 T1B T2 T1 T2 T3 T2 T2B T2 T1 T1 T1B T4 T1B T2A T2A T1A T3 T2 T1B T2 T2 T1B T2A T2A T2B T3 T2 T1B T1A T1 T2A T1 T1B T1B T2A T2 T1 T2 T1 T3 T1 T1B T2 T2A T2 T2 T2A T1B T1A T2 T2 T2 T2 T2 T3 T2A T2 T2A T1B T2 T2B T1A T1 T1 T2 T1 T2 T2 T1 T2A T2B T1 T1B T2A T2 T3 T1B T1 T2 T2 T1 T3 T2 T2 T1 T2A T1 T3 T1 T2 T2 T2 T2 T2 T2 T1 T2 T2 T1A T1A T1B T2B T1B T1B T1A T2 T1A T1B T2B T1 T2 T2 T1 T1A T2A T2A T3 T1B T1B T2 T2A T2B T1B T2A T3 T3 T1A T2 T2 T3 T2 T2 T1 T2 T1A T2A T3 T2A T1B T2 T2 T1 T3 T1A T2 T2 T2A T2 T2 T2 T2 T3 T1A T2A T1 T1 T2 T1 T1A T1 T2 T2 T2 T2 T4 T4 T1 T1 T2 T2 T3 T1 T4 T2 T1 T1B T2A T1B T2A T2 T2 T2A T2B T1 T2A T1B T1B T2B T2 T2A T1A T1B T2A TX T1B T1A T1A T2A T1 T1A T1A T1B T1A T2 T2 T1 T2A T2A T2A T2A T1A T1A T4
10
+ KRAS CNA amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec
11
+ HRAS CNA Deep Deletion amp_rec Deep Deletion Deep Deletion Deep Deletion
12
+ BRAF CNA amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec
13
+ RAF1 CNA amp_rec
14
+ MAP3K1 CNA Amplification Amplification Amplification homdel_rec Amplification homdel_rec homdel_rec
15
+ MAP3K2 CNA Amplification
16
+ MAP3K3 CNA Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification
17
+ MAP3K4 CNA Deep Deletion Deep Deletion Deep Deletion Amplification Deep Deletion
18
+ MAP3K5 CNA Deep Deletion Deep Deletion Amplification Amplification Deep Deletion
19
+ MAP2K1 CNA Amplification
20
+ MAP2K2 CNA Deep Deletion Deep Deletion Deep Deletion
21
+ MAP2K3 CNA Deep Deletion Deep Deletion Amplification Amplification Amplification Amplification Deep Deletion Deep Deletion
22
+ MAP2K4 CNA homdel_rec homdel_rec homdel_rec homdel_rec homdel_rec homdel_rec Amplification
23
+ MAP2K5 CNA Amplification Deep Deletion
24
+ MAPK1 CNA amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec amp_rec
25
+ MAPK3 CNA Amplification Amplification Amplification Amplification Amplification
26
+ MAPK4 CNA Deep Deletion Deep Deletion Deep Deletion Deep Deletion Deep Deletion Deep Deletion Deep Deletion Deep Deletion Deep Deletion
27
+ MAPK6 CNA Deep Deletion Deep Deletion Deep Deletion Deep Deletion
28
+ MAPK7 CNA Amplification Amplification Deep Deletion Deep Deletion Deep Deletion Amplification Amplification Amplification Amplification Deep Deletion
29
+ MAPK8 CNA Amplification Amplification Deep Deletion Deep Deletion Deep Deletion Deep Deletion
30
+ MAPK9 CNA Deep Deletion Amplification Amplification Amplification Amplification Amplification Deep Deletion Amplification Deep Deletion Amplification Amplification Amplification Deep Deletion
31
+ MAPK12 CNA Deep Deletion Amplification Deep Deletion Deep Deletion Deep Deletion Deep Deletion Deep Deletion Deep Deletion Amplification Deep Deletion Deep Deletion
32
+ MAPK14 CNA Amplification Amplification Amplification Amplification
33
+ DAB2 CNA Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification
34
+ RASSF1 CNA
35
+ RAB25 CNA Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification Amplification
36
+ KRAS MUTATIONS Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver)
37
+ HRAS MUTATIONS Missense Mutation (putative passenger) Missense Mutation (putative driver) Missense Mutation (putative passenger)
38
+ BRAF MUTATIONS Missense Mutation (putative driver) Truncating mutation (putative passenger) splice Missense Mutation (putative passenger) Inframe Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger)
39
+ RAF1 MUTATIONS Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative passenger) Missense Mutation (putative passenger)
40
+ MAP3K1 MUTATIONS Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Truncating mutation (putative driver) Missense Mutation (putative passenger)
41
+ MAP3K2 MUTATIONS Missense Mutation (putative passenger) Missense Mutation (putative passenger) Truncating mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger)
42
+ MAP3K3 MUTATIONS Truncating mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Truncating mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger)
43
+ MAP3K4 MUTATIONS Truncating mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) splice Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger)
44
+ MAP3K5 MUTATIONS Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Truncating mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Truncating mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger)
45
+ MAP2K1 MUTATIONS Missense Mutation (putative driver) Truncating mutation (putative passenger) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative driver) Missense Mutation (putative passenger) Missense Mutation (putative passenger)
46
+ MAP2K2 MUTATIONS Missense Mutation (putative passenger)
47
+ MAP2K3 MUTATIONS Missense Mutation (putative passenger) Missense Mutation (putative passenger) splice Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger)
48
+ MAP2K4 MUTATIONS Missense Mutation (putative passenger) Missense Mutation (putative passenger) splice_rec Truncating mutation (putative driver) splice_rec Missense Mutation (putative passenger) Truncating mutation (putative driver) Missense Mutation (putative driver)
49
+ MAP2K5 MUTATIONS Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger)
50
+ MAPK1 MUTATIONS Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger)
51
+ MAPK3 MUTATIONS Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger)
52
+ MAPK4 MUTATIONS Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Truncating mutation (putative passenger) Missense Mutation (putative passenger) Truncating mutation (putative passenger) Missense Mutation (putative passenger)
53
+ MAPK6 MUTATIONS Missense Mutation (putative passenger) Missense Mutation (putative passenger) Truncating mutation (putative passenger) Missense Mutation (putative passenger)
54
+ MAPK7 MUTATIONS Missense Mutation (putative passenger) Missense Mutation (putative passenger) Truncating mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger)
55
+ MAPK8 MUTATIONS Truncating mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger)
56
+ MAPK9 MUTATIONS Missense Mutation (putative passenger) splice Truncating mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger)
57
+ MAPK12 MUTATIONS Missense Mutation (putative passenger)
58
+ MAPK14 MUTATIONS Missense Mutation (putative passenger) Missense Mutation (putative passenger) Truncating mutation (putative passenger) splice
59
+ DAB2 MUTATIONS Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) splice Missense Mutation (putative passenger) Truncating mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger) Missense Mutation (putative passenger)
60
+ RASSF1 MUTATIONS Missense Mutation (putative passenger) splice
61
+ RAB25 MUTATIONS Missense Mutation (putative passenger) Truncating mutation (putative passenger) Truncating mutation (putative passenger)
62
+ KRAS MRNA
63
+ HRAS MRNA
64
+ BRAF MRNA
65
+ RAF1 MRNA
66
+ MAP3K1 MRNA
67
+ MAP3K2 MRNA
68
+ MAP3K3 MRNA
69
+ MAP3K4 MRNA
70
+ MAP3K5 MRNA
71
+ MAP2K1 MRNA
72
+ MAP2K2 MRNA
73
+ MAP2K3 MRNA
74
+ MAP2K4 MRNA
75
+ MAP2K5 MRNA
76
+ MAPK1 MRNA
77
+ MAPK3 MRNA
78
+ MAPK4 MRNA
79
+ MAPK6 MRNA
80
+ MAPK7 MRNA
81
+ MAPK8 MRNA
82
+ MAPK9 MRNA
83
+ MAPK12 MRNA
84
+ MAPK14 MRNA
85
+ DAB2 MRNA
86
+ RASSF1 MRNA
87
+ RAB25 MRNA
88
+ KRAS PROTEIN
89
+ HRAS PROTEIN
90
+ BRAF PROTEIN
91
+ RAF1 PROTEIN
92
+ MAP3K1 PROTEIN
93
+ MAP3K2 PROTEIN
94
+ MAP3K3 PROTEIN
95
+ MAP3K4 PROTEIN
96
+ MAP3K5 PROTEIN
97
+ MAP2K1 PROTEIN
98
+ MAP2K2 PROTEIN
99
+ MAP2K3 PROTEIN
100
+ MAP2K4 PROTEIN
101
+ MAP2K5 PROTEIN
102
+ MAPK1 PROTEIN
103
+ MAPK3 PROTEIN
104
+ MAPK4 PROTEIN
105
+ MAPK6 PROTEIN
106
+ MAPK7 PROTEIN
107
+ MAPK8 PROTEIN
108
+ MAPK9 PROTEIN
109
+ MAPK12 PROTEIN
110
+ MAPK14 PROTEIN
111
+ DAB2 PROTEIN
112
+ RASSF1 PROTEIN
113
+ RAB25 PROTEIN
114
+ KRAS STRUCTURAL_VARIANT sv
115
+ HRAS STRUCTURAL_VARIANT
116
+ BRAF STRUCTURAL_VARIANT
117
+ RAF1 STRUCTURAL_VARIANT
118
+ MAP3K1 STRUCTURAL_VARIANT
119
+ MAP3K2 STRUCTURAL_VARIANT sv_rec
120
+ MAP3K3 STRUCTURAL_VARIANT
121
+ MAP3K4 STRUCTURAL_VARIANT
122
+ MAP3K5 STRUCTURAL_VARIANT sv
123
+ MAP2K1 STRUCTURAL_VARIANT
124
+ MAP2K2 STRUCTURAL_VARIANT
125
+ MAP2K3 STRUCTURAL_VARIANT
126
+ MAP2K4 STRUCTURAL_VARIANT sv_rec
127
+ MAP2K5 STRUCTURAL_VARIANT
128
+ MAPK1 STRUCTURAL_VARIANT sv sv
129
+ MAPK3 STRUCTURAL_VARIANT
130
+ MAPK4 STRUCTURAL_VARIANT
131
+ MAPK6 STRUCTURAL_VARIANT
132
+ MAPK7 STRUCTURAL_VARIANT
133
+ MAPK8 STRUCTURAL_VARIANT
134
+ MAPK9 STRUCTURAL_VARIANT
135
+ MAPK12 STRUCTURAL_VARIANT
136
+ MAPK14 STRUCTURAL_VARIANT
137
+ DAB2 STRUCTURAL_VARIANT
138
+ RASSF1 STRUCTURAL_VARIANT
139
+ RAB25 STRUCTURAL_VARIANT sv
140
+ KRAS HEATMAP MRNA_EXPRESSION Z-SCORE 5.9959 10.8738 2.2105 2.0675 5.3943 3.2589 12.8384 0.7326 0.7117 0.7026 2.8756 1.9783 3.0366 -0.0661 3.6727 1.0036 46.4916 0.3049 4.4689 1.0634 29.4742 -0.5728 1.8778 5.5716 3.5456 8.2031 3.9262 5.4721 4.6478 0.1123 0.1515 8.0209 0.6272 -0.1068 5.2224 2.446 2.826 -0.6508 1.5376 0.1478 2.2985 1.6738 0.3561 1.135 2.7383 3.5498 0.1739 -0.3485 0.0863 -0.3745 1.4951 1.2232 0.5113 -0.7657 1.404 1.0198 0.4801 -1.2293 1.3359 0.2889 -0.3665 0.6597 2.6239 2.2577 -0.7264 1.7587 1.8423 1.2775 -0.4632 -0.8326 -0.3808 -0.1314 1.9463 -0.0433 -0.0441 0.7451 1.2146 1.0379 0.6309 0.0607 2.0187 0.0828 1.2209 -0.3506 -0.2342 -0.4316 0.4829 0.1667 -0.457 -0.6716 0.8753 2.6562 -0.1325 -0.2857 1.7741 -0.2481 0.2805 -1.1629 0.25 -0.1084 -0.3825 1.6685 0.4616 0.5681 1.1997 3.2932 1.3273 1.392 0.2059 0.1154 0.2524 2.2299 2.7734 -0.1772 2.5391 0.233 0.3415 -0.598 -0.7259 0.8637 0.7725 1.0073 1.1948 0.5313 0.9827 1.7216 0.6588 0.8829 -0.0919 0.1321 0.1919 -0.376 5.4631 -0.1283 0.7925 0.8418 -0.315 0.697 0.0443 1.3461 1.0507 1.1949 -0.0771 0.5301 1.4607 0.1681 0.4156 -0.2125 0.5312 1.6225 -0.0226 -0.1384 -0.2257 1.0703 0.4596 -0.3098 -0.1257 0.9843 0.0853 5.3291 0.1312 -0.749 -0.0014 -0.2911 -0.4175 0.0255 0.6238 -0.2909 2.8486 -0.294 0.0485 -0.6572 0.2976 0.4606 0.2395 -0.9356 -0.2377 -0.4301 0.248 -0.3104 -1.4182 -0.1092 0.5692 -0.658 -1.1978 0.7377 -0.4987 0.0002 -0.1085 -0.0389 3.005 -0.3942 -1.0945 -1.0664 -1.2365 -0.9595 -0.6949 -0.1561 -0.1655 -0.4336 -0.6569 -0.2388 -0.5706 -0.0816 -0.2288 -1.128 -0.2718 -0.2731 0.5324 -0.7446 0.2821 -0.7367 -1.1183 0.1906 0.2617 3.9765 -0.2461 -0.1183 -0.4502 1.5495 -0.193 -0.8029 0.2262 1.2825 -0.1862 -0.8218 -0.8844 -0.9817 1.1544 -0.1327 -0.0885 -0.2137 0.0179 -0.9046 0.2723 -0.477 -0.6857 1.3203 -0.822 1.2885 -0.2653 -0.007 0.2883 0.1164 0.9335 -0.7021 -0.6273 -0.4681 0.0296 -0.6129 -0.3299 0.771 2.8092 1.7289 0.2016 -0.6463 -0.5454 -0.1363 1.9753 -0.3466 0.1212 -0.9879 -0.7475 -0.7561 -0.7564 -0.6035 0.9476 1.0215 -1.1859 -1.5405 0.5459 -0.3643 2.7427 -0.9066 1.6308 -0.2713 4.9542 -1.0621 -0.3741 -0.4504 -1.4777 -0.8332 -0.1614 -0.2637 1.4138 -0.8999 -0.3165 0.4096 -0.378 0.2803 0.0612 -0.8436 0.9872 0.9804 0.6819 0.627 0.6587 -0.0967 -1.4207 -0.8196 -0.303 -1.431 -0.3335 0.6695 -0.3331 0.2852 -0.6395 1.9335 -0.3798 -0.6152 0.3311 -0.2564 -1.4376 -0.5959 -0.9318 -0.1503 0.358 0.0232 0.566 -0.8264 -0.3923 -0.0586 -0.9765 1.1288 0.3479 -0.9097 -0.634 -0.702 -0.0682 -0.0762 -1.256 2.3518 -0.0132 0.0748 -0.2702 0.5958 -1.4786 0.8772 10.0927 -1.0237 -0.1606 -0.7806 0.7009 -0.0353 -0.311 -0.5273 0.419 -1.2317 -0.5089 -0.4344 -0.9232 -0.4109 -1.2887 0.1405 -0.9303 0.2946 -0.3185 -0.3361 0.6198 -0.1464 0.7769 6.9447 -0.6159 -1.313 -0.6235 -0.1591 0.9241 2.5504 -1.1373 -1.3499 -0.9889 -0.8939 -0.6956 -0.3613 0.1082 0.6392 0.5394 -0.4668 0.0453 -0.6234 0.0248 -0.7435 1.9094 0.2077 -0.8627 -0.2156 -0.647 -0.7132 -1.2394 -0.4096 -1.1751 -0.3107 -0.1184 -0.842 -0.5409 -0.5487 -0.7208 -0.4429 -0.86 1.0495 0.0472 1.1281 -1.0266 -0.0227 -0.4577 0.6105 0.7388 -0.2919 0.8532 -0.1716 -0.2978 -0.3094 -0.5161 -0.685 -0.6185 -0.5259 -0.6928 -0.5309 0.4196 1.556 -0.9026 0.2408 -0.6795 -0.4364 -0.2712 -0.1195 -0.7635 0.2288 0.2262 0.3621 -0.191 1.172 -0.4129 -0.0991 -0.8707 -0.4152 -0.8593 -0.92 -0.5721 -0.9393 -0.6924 -0.7112 1.2844 -1.0549 -0.8247 -1.3371 0.0253 -1.1746 -0.5145 0.5341 0.3412 -1.4538 1.8584 0.1379 -0.4084 -0.3361 0.9544 -0.5126 -1.146 -0.5647 -0.8145 0.3724 -0.356 -0.4718 -1.5445 -0.1464 -0.0558 -0.9016 -0.1551 -0.5188 -0.3713 -1.0937 -0.5174 0.3012 -0.0854 -0.9893 0.3772 -1.0429 0.8697 -0.7861 -0.8162 1.5488 -1.0865 -0.7378 -0.6645 0.0625 -0.6491 -0.6246 -0.7367 -1.2242 -0.7162 0.1127 -1.1248 0.237 0.6429 -0.619 -0.251 -0.8257 1.7879 0.4693 -0.8262 -1.1207 0.6411
141
+ HRAS HEATMAP MRNA_EXPRESSION Z-SCORE -0.8059 -1.2021 -0.5957 0.3468 -0.4467 0.4396 0.215 -0.5369 0.0934 -0.6172 -0.3714 -0.3717 -0.7345 0.9824 -1.737 -0.1661 0.4525 0.2701 -1.0458 -0.6976 -0.2395 0.8136 0.2933 -0.6593 -1.1326 -0.6001 -0.8827 -0.2041 0.2178 0.2215 -0.205 0.5936 0.5353 -0.4933 -0.7215 -0.5172 -0.4236 0.7458 -0.5947 0.4608 -0.0813 -0.5449 -0.5228 -0.5907 1.0298 0.2171 1.2404 0.3098 0.5224 0.913 0.9869 -0.7009 -1.0805 0.659 0.3461 -0.5998 -0.0394 0.142 -0.1461 1.5847 -0.457 -0.727 -1.1374 0.0539 -0.0285 0.0094 0.7571 -0.3987 -0.9232 -0.0531 -0.5236 0.1034 -0.1142 -0.3289 0.1479 0.4961 -0.1982 -0.0178 -1.0076 0.3049 -0.8216 -0.6414 0.2224 -0.94 -0.6197 0.3827 -1.2969 -0.2099 0.3108 1.4152 -0.9284 0.5484 -0.3899 0.1227 -0.3435 -0.1148 1.2846 4.3208 -0.8476 0.1021 2.1349 -0.0858 -0.6881 0.3684 -0.1714 0.5003 -0.6861 -0.8022 -1.0886 0.2843 0.191 0.268 -1.6691 1.5655 0.274 -1.2311 -0.6844 0.0985 2.2384 1.1637 -0.8079 -0.2649 -0.1404 2.1135 -0.2911 -0.1996 -0.6542 0.0274 -0.05 -0.6463 -0.1531 -0.6536 0.7659 -0.2718 1.4003 -0.4075 -0.6921 0.5963 0.4532 -0.0488 -1.1068 -0.3134 2.713 0.6383 0.5627 0.3583 -0.1774 0.8559 1.9181 -0.1662 -0.9012 -0.3511 1.1905 1.5179 0.6967 2.7148 2.5476 -0.4795 -0.1751 -0.6256 -1.1792 -0.4448 0.3727 -0.3949 0.8745 -0.5866 1.6411 -1.2663 -1.4416 -1.4639 2.2051 2.7837 -0.7242 0.2456 1.3277 0.7064 -1.4403 -1.0405 0.2428 -1.1877 -0.2126 -0.3069 -0.4007 -0.7569 0.8014 0.1522 -0.5594 -1.2114 -0.539 -0.9379 0.2071 -0.6571 -0.8652 4.3516 -1.2539 -1.0742 -1.0697 -0.0738 -0.4639 0.4226 0.9747 -0.6449 0.2085 -0.4852 -1.1535 0.8565 -0.8516 -0.2134 -0.2257 0.1136 -0.5575 -0.2317 -0.2212 -1.1931 -0.8644 -0.8351 3.6811 -0.8845 0.1635 -1.1935 0.5516 -1.1737 -0.4948 -0.5229 -0.6678 -0.9285 2.0272 -0.1619 0.4366 -1.039 -1.1524 0.4163 0.1357 0.178 -0.523 -0.4571 0.9181 -0.4967 0.1656 0.1871 1.5689 -1.0752 -0.5304 -0.1949 -1.0521 -0.5333 -1.2954 0.2137 1.4276 0.1929 1.6777 -0.9001 -0.1644 0.2046 0.0827 -0.1553 -0.7135 0.6342 0.4111 -1.3666 -0.5949 1.5433 0.9962 -0.4291 -0.1328 0.2313 -1.0944 0.1374 1.2328 -0.736 -0.2977 -0.529 -0.2613 0.7489 -0.8967 -0.5955 -1.2921 -0.608 -0.1984 -1.1183 2.2807 -0.5771 -0.2378 -0.0447 -1.0138 -1.1065 0.0739 -0.2522 0.0835 -0.4575 0.0486 -1.2459 0.0145 -1.2255 -0.3645 1.1805 -0.5084 -1.0322 -0.1876 -1.0233 -0.7888 -0.8856 -0.52 -0.6321 -0.2381 -0.8059 -0.8217 -1.2309 0.1438 -0.1286 1.8475 0.1468 -1.3846 1.2504 -0.1477 0.2234 0.3462 0.8703 0.3797 -0.3038 -0.0066 -0.8193 0.3397 -0.637 -0.5948 0.8414 0.7918 -0.6856 0.2922 -0.4253 1.5618 -0.5735 -0.3817 -0.215 -0.5244 -0.0357 0.1405 -0.5355 0.6644 -0.3356 -0.4087 1.2933 0.1657 0.4448 -0.9195 -0.3221 -0.7458 0.4081 0.3097 -0.4266 -0.5736 -1.0838 -0.6236 -0.6805 -0.0219 -0.5591 -0.7792 -0.8534 -0.5596 -0.517 0.5975 6.2338 -0.9299 -0.6449 -0.3876 -0.5133 0.747 0.7895 -0.2725 4.2201 -0.0578 0.1778 3.51 -0.0434 1.6934 0.9181 -0.3878 -1.1591 -0.5497 0.0577 -0.5222 -0.1673 -0.431 1.1899 -0.8574 -0.3599 -0.7144 0.5564 1.3081 -0.7389 -1.0792 -0.3985 -0.4249 -0.8897 0.6032 3.1918 -1.2513 -0.4448 0.0798 0.0771 -0.6493 0.2112 0.0078 -0.9146 -0.4005 0.0143 -1.4135 -1.3478 -0.7842 -0.2499 -0.1949 -0.997 0.6966 -0.8994 -0.447 -0.5577 -0.4523 0.6141 -0.3744 0.5703 0.181 -0.4888 -0.3031 -0.5784 -0.8192 -0.6219 -0.5446 -0.9428 -0.9063 -0.6933 -0.2528 -0.3236 -0.5782 0.3281 -0.3029 0.1065 -0.7042 -0.3396 -1.1802 -0.9645 2.7827 -0.8687 -0.1183 -0.2301 0.047 -0.0535 -0.734 0.3973 -0.3605 -0.62 -0.754 -0.0615 -0.7705 -0.2748 -0.4828 -0.9504 -0.0725 -0.0442 2.6515 3.4828 -0.2508 0.5474 0.9223 -0.3626 -1.0807 -0.5958 0.1831 -0.5938 -0.9994 -0.7219 -0.6911 0.1766 -0.7858 -0.2748 0.1319 -0.9305 -0.1551 -0.4157 0.6913 -0.8985 -0.0322 2.0451 -0.2543 0.0723 0.8686 -0.6143 0.9033 0.514 -0.5102 -0.4659 0.0031 0.738 -0.3554 -0.5872 -1.0541 -1.1237 -0.4181 -0.6834 -0.233 0.6283 -0.2857 0.0663 -0.8333
142
+ BRAF HEATMAP MRNA_EXPRESSION Z-SCORE -0.6797 5.2897 1.1695 -0.5823 0.6957 0.3878 -0.2288 6.457 -0.0376 0.1552 -0.7719 -0.806 -0.1669 -0.7157 1.3445 -1.4305 -0.6077 -0.472 0.9694 -0.5062 0.234 0.4231 0.1911 1.1261 1.765 0.9869 0.0806 0.9527 1.4801 0.0798 0.5021 0.2506 -0.219 1.968 -0.4606 2.6243 0.9452 0.0366 -0.4446 -1.3862 1.0102 1.4866 0.9629 1.54 0.1419 3.1445 0.2931 -0.1899 1.3636 0.3706 2.865 -0.3203 1.2085 0.493 -0.6111 -0.5914 -0.334 -0.5398 -0.7969 -0.8552 -1.8046 -0.2221 0.4466 2.0944 -0.4427 4.6638 -0.8682 0.1457 0.4255 -0.419 -0.7318 -0.507 -0.7639 1.0084 -0.4548 -0.206 0.6103 -0.5936 1.8626 -0.9179 2.5166 0.265 -0.4631 2.2256 0.6027 -1.2418 -0.4916 -0.0591 -1.082 3.223 0.5117 -0.5904 -0.9426 1.1848 -0.3542 -0.0692 -0.9451 1.3369 -0.2397 -1.3771 -0.2649 -0.3441 1.4461 2.1204 -0.0448 0.2577 -0.1469 1.0324 0.3374 -0.5561 -0.9589 -1.3297 0.2968 -1.6194 0.0651 1.137 1.4406 -0.8268 -0.6435 -0.72 0.9423 -0.938 -1.2365 -0.4282 -0.0448 1.4 0.9357 0.1461 -0.5159 -0.5515 0.0755 -0.3624 0.0645 -0.726 -0.3243 -0.8689 4.2065 -0.1621 -0.5945 0.1189 1.624 -0.7784 -0.3253 -0.3438 -1.3003 -0.4937 -0.5277 -0.6228 0.4728 2.2078 -0.4353 -0.2032 -0.9302 -0.4885 -0.2419 -0.7866 4.7418 0.6211 -1.2339 1.3845 0.5108 -0.7222 -0.9678 0.2832 -0.0755 -1.1743 -1.0083 2.5122 0.1778 3.1969 -0.012 0.0354 2.2262 0.9093 -0.1464 0.4253 2.5207 0.2035 1.3389 1.9186 1.7137 -0.2654 2.2392 -0.3996 -1.2892 -0.4742 0.5299 2.7226 1.7458 0.0864 0.523 1.0341 0.8068 -1.7386 0.5963 3.369 1.7016 0.0006 1.0281 -0.3293 -0.8416 -0.2786 -0.4047 -0.8601 0.5637 -1.0292 -0.2981 1.1655 -0.7953 0.1703 -0.2879 -0.8701 -0.0567 1.639 0.7825 0.2416 0.5757 2.2804 0.3221 2.4918 0.8396 1.3989 0.3737 1.7044 0.0833 -0.9458 -1.1202 0.3997 0.1132 3.7591 -0.591 1.0031 3.6399 -0.2797 -0.2303 -0.3658 -0.3442 2.766 -1.012 1.3627 -0.3952 -0.0127 1.8049 0.2078 0.3837 -0.0967 -0.3174 0.0524 0.7473 0.0741 -0.5059 0.7404 0.7076 0.0418 -0.2929 0.66 2.5066 -0.3603 2.5796 3.1886 0.4369 -0.7066 0.5298 0.7503 -0.0027 -1.0712 2.4244 0.1205 0.8775 1.8649 -1.114 2.4003 0.7969 -1.6063 5.3607 0.7628 1.8041 -0.7188 0.8307 -0.5612 -1.4368 -0.9172 -0.7511 -0.1751 1.0754 2.8723 -0.4021 0.1387 -0.0876 1.5533 0.2703 0.2361 -0.5347 0.1514 0.0456 1.4433 0.0075 0.0057 -0.2996 0.7196 -0.216 -0.1382 1.0337 1.2602 -0.3885 -0.1095 -0.8055 3.0395 0.9613 0.4522 -1.0876 -1.0667 -0.1013 -0.5101 1.6176 -0.6092 0.121 -0.8504 2.9531 -1.3087 0.8213 4.5849 0.474 1.3423 -0.7672 0.219 1.128 -0.3703 -0.292 -0.4438 -1.4071 0.9035 -0.6645 3.1698 0.5511 2.2373 -0.2552 1.4558 -0.5171 1.2015 -0.6755 0.0587 0.1029 -0.1955 0.8542 -0.9634 -0.3186 6.2864 -1.828 -0.6486 0.5921 1.8538 -0.2398 0.044 -0.5976 -0.5903 1.9656 -0.3758 1.071 0.2532 0.3611 6.6428 -0.0593 -0.309 0.0046 -0.359 0.5919 1.3922 0.8665 0.0261 -1.5957 -0.4893 -0.6591 0.4746 0.1279 -1.6323 -1.6649 1.9836 4.7576 -1.6111 -0.3085 -0.8042 -0.3184 -0.2403 0.0297 0.8153 -0.0775 -0.7963 -1.5813 0.4968 -1.0368 0.0749 -0.2793 0.703 -1.2054 -1.0681 0.3515 -0.8086 -0.2892 -0.0403 -0.1817 -0.5616 -0.6448 0.5462 0.3097 0.3702 4.1225 4.1168 -0.0021 -0.1181 0.7801 -0.8373 0.5753 0.5518 0.2279 -0.6973 -0.8922 -0.3987 -0.1426 -0.9519 0.8421 -0.1653 -1.149 0.893 -0.1394 -0.8105 0.8544 0.1832 0.1675 -0.3644 0.4122 0.8291 2.4866 0.1052 -0.2387 1.5401 -0.6799 0.4203 3.0795 0.6632 -0.7551 -0.7891 -0.4355 0.1079 -0.0836 1.0853 -0.1115 1.516 -0.9256 -0.0634 -0.4802 -1.0947 -0.2691 -0.0104 0.2664 1.9216 1.3642 -0.3868 -0.839 -0.9888 -0.5746 -0.3058 -0.6229 0.0854 1.4134 -0.2058 0.0217 -0.7912 0.5648 1.1579 -0.4215 -0.4223 1.6705 -0.4771 0.6029 -0.726 1.2529 -0.8094 0.3971 0.926 -0.0212 -0.3117 -0.4644 -0.6066 -0.0809 -0.5599 -0.7708 0.1994 -0.3934 -1.0398 -1.1508 0.3718 -1.0377 0.8356 0.0788 -0.4651 2.0759 7.0309 0.7332 0.305 -0.1679 -0.1476 2.3042
143
+ MAPK8IP2 (cg00083937) HEATMAP GENERIC_ASSAY LIMIT-VALUE 0.600965908700663 0.514129069512132 0.769616641690092 0.69812664900243 0.799070919493019 0.735822579583125 0.361008209097112 0.630354044620056 0.626547559612314 0.715710531319197 0.629244814371861 0.737656897529819 0.631317319529248 0.560801391326944 0.446508340566739 0.494495895449146 0.777196348486248 0.70467195003229 0.568177326882578 0.605151639161332 0.631970855102427 0.639893740824469 0.469277343052793 0.592016656230102 0.631495104286855 0.696596129116654 0.466458994811162 0.74794604636645 0.709598624518612 0.578363580171894 0.671326781721952 0.726293257054276 0.569576596385253 0.74193323660488 0.546128434149204 0.678669647839654 0.730559995413672 0.710371003703426 0.731458127750535 0.58637604815133 0.580711686284361 0.372407720942255 0.7162344613192 0.708918226072652 0.688768035781728 0.403909915566069 0.497916780961814 0.697540166283395 0.473165975877545 0.797027064221362 0.748671599388255 0.727224771974673 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144
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145
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146
+ Dicipivirus HEATMAP GENERIC_ASSAY LIMIT-VALUE 1.8185390668 2.9958157746 3.1483151867 3.8482461707 3.1845768492 2.6051289983 2.8977495319 1.3608220132 4.7837371528 5.3000490773 -0.287895388 3.1926412799 2.1924062539 4.6237596621 2.0970512375 2.2858682553 3.388857917 4.0315004504 2.8395832815 2.9664760641 3.4405264435 4.161098499 3.5480676519 4.7908230928 4.5928349723 4.9102264357 4.0078422938 4.3526106412 4.4543926636 0.584098188 3.5909929451 3.5692383519 4.5750743197 3.6395692447 4.8756933309 5.2922517931 3.0510258911 1.2963188259 2.056290474 4.1535971926 1.5005348841 3.0895591183 3.2877618102 4.6832688518 3.2363300978 4.3513795427 4.93151258 3.4347446835 1.6778644348 4.2792341802 3.4317276841 3.2631308391 3.2782558637 4.6951093699 3.8533076059 4.0891277464 4.5043736351 2.9027749344 2.4913463095 2.7467323026 3.1658501913 2.3694603241 1.634602479 3.8069833661 2.4199755771 3.1258990454 0.7525231735 4.4373609588 4.2746133528 2.4204167468 3.6877213373 3.6247297843 3.2371523336 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