boltz-api 0.39.2 → 0.40.0

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (32) hide show
  1. package/CHANGELOG.md +16 -0
  2. package/package.json +1 -1
  3. package/resources/predictions/structure-and-binding.d.mts +108 -16
  4. package/resources/predictions/structure-and-binding.d.mts.map +1 -1
  5. package/resources/predictions/structure-and-binding.d.ts +108 -16
  6. package/resources/predictions/structure-and-binding.d.ts.map +1 -1
  7. package/resources/protein/design.d.mts +382 -44
  8. package/resources/protein/design.d.mts.map +1 -1
  9. package/resources/protein/design.d.ts +382 -44
  10. package/resources/protein/design.d.ts.map +1 -1
  11. package/resources/protein/library-screen.d.mts +216 -32
  12. package/resources/protein/library-screen.d.mts.map +1 -1
  13. package/resources/protein/library-screen.d.ts +216 -32
  14. package/resources/protein/library-screen.d.ts.map +1 -1
  15. package/resources/small-molecule/design.d.mts +85 -10
  16. package/resources/small-molecule/design.d.mts.map +1 -1
  17. package/resources/small-molecule/design.d.ts +85 -10
  18. package/resources/small-molecule/design.d.ts.map +1 -1
  19. package/resources/small-molecule/library-screen.d.mts +45 -10
  20. package/resources/small-molecule/library-screen.d.mts.map +1 -1
  21. package/resources/small-molecule/library-screen.d.ts +45 -10
  22. package/resources/small-molecule/library-screen.d.ts.map +1 -1
  23. package/src/resources/predictions/structure-and-binding.ts +108 -16
  24. package/src/resources/protein/design.ts +390 -44
  25. package/src/resources/protein/library-screen.ts +216 -32
  26. package/src/resources/small-molecule/design.ts +93 -10
  27. package/src/resources/small-molecule/library-screen.ts +45 -10
  28. package/src/version.ts +1 -1
  29. package/version.d.mts +1 -1
  30. package/version.d.ts +1 -1
  31. package/version.js +1 -1
  32. package/version.mjs +1 -1
package/resources/protein/library-screen.d.ts CHANGED
@@ -341,17 +341,24 @@ export declare namespace LibraryScreenRetrieveResponse {
341
341
  */
342
342
  cyclic?: boolean;
343
343
  /**
344
- * Post-translational modifications. Optional; defaults to an empty list when
345
- * omitted.
344
+ * CCD post-translational modifications. Optional; defaults to an empty list when
345
+ * omitted. SMILES modifications are not supported.
346
346
  */
347
347
  modifications?: Array<ProteinEntityResponse.Modification>;
348
348
  }
349
349
  namespace ProteinEntityResponse {
350
+ /**
351
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
352
+ * are not accepted.
353
+ */
350
354
  interface Modification {
351
355
  /**
352
356
  * 0-based index of the residue to modify
353
357
  */
354
358
  residue_index: number;
359
+ /**
360
+ * Modification format. Only CCD polymer modifications are supported.
361
+ */
355
362
  type: 'ccd';
356
363
  /**
357
364
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for
@@ -375,16 +382,24 @@ export declare namespace LibraryScreenRetrieveResponse {
375
382
  */
376
383
  cyclic?: boolean;
377
384
  /**
378
- * Chemical modifications. Optional; defaults to an empty list when omitted.
385
+ * CCD chemical modifications. Optional; defaults to an empty list when omitted.
386
+ * SMILES modifications are not supported.
379
387
  */
380
388
  modifications?: Array<RnaEntityResponse.Modification>;
381
389
  }
382
390
  namespace RnaEntityResponse {
391
+ /**
392
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
393
+ * are not accepted.
394
+ */
383
395
  interface Modification {
384
396
  /**
385
397
  * 0-based index of the residue to modify
386
398
  */
387
399
  residue_index: number;
400
+ /**
401
+ * Modification format. Only CCD polymer modifications are supported.
402
+ */
388
403
  type: 'ccd';
389
404
  /**
390
405
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for
@@ -408,16 +423,24 @@ export declare namespace LibraryScreenRetrieveResponse {
408
423
  */
409
424
  cyclic?: boolean;
410
425
  /**
411
- * Chemical modifications. Optional; defaults to an empty list when omitted.
426
+ * CCD chemical modifications. Optional; defaults to an empty list when omitted.
427
+ * SMILES modifications are not supported.
412
428
  */
413
429
  modifications?: Array<DnaEntityResponse.Modification>;
414
430
  }
415
431
  namespace DnaEntityResponse {
432
+ /**
433
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
434
+ * are not accepted.
435
+ */
416
436
  interface Modification {
417
437
  /**
418
438
  * 0-based index of the residue to modify
419
439
  */
420
440
  residue_index: number;
441
+ /**
442
+ * Modification format. Only CCD polymer modifications are supported.
443
+ */
421
444
  type: 'ccd';
422
445
  /**
423
446
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for
@@ -848,17 +871,24 @@ export declare namespace LibraryScreenListResultsResponse {
848
871
  */
849
872
  cyclic?: boolean;
850
873
  /**
851
- * Post-translational modifications. Optional; defaults to an empty list when
852
- * omitted.
874
+ * CCD post-translational modifications. Optional; defaults to an empty list when
875
+ * omitted. SMILES modifications are not supported.
853
876
  */
854
877
  modifications?: Array<ProteinEntity.Modification>;
855
878
  }
856
879
  namespace ProteinEntity {
880
+ /**
881
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
882
+ * are not accepted.
883
+ */
857
884
  interface Modification {
858
885
  /**
859
886
  * 0-based index of the residue to modify
860
887
  */
861
888
  residue_index: number;
889
+ /**
890
+ * Modification format. Only CCD polymer modifications are supported.
891
+ */
862
892
  type: 'ccd';
863
893
  /**
864
894
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for
@@ -882,16 +912,24 @@ export declare namespace LibraryScreenListResultsResponse {
882
912
  */
883
913
  cyclic?: boolean;
884
914
  /**
885
- * Chemical modifications. Optional; defaults to an empty list when omitted.
915
+ * CCD chemical modifications. Optional; defaults to an empty list when omitted.
916
+ * SMILES modifications are not supported.
886
917
  */
887
918
  modifications?: Array<RnaEntity.Modification>;
888
919
  }
889
920
  namespace RnaEntity {
921
+ /**
922
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
923
+ * are not accepted.
924
+ */
890
925
  interface Modification {
891
926
  /**
892
927
  * 0-based index of the residue to modify
893
928
  */
894
929
  residue_index: number;
930
+ /**
931
+ * Modification format. Only CCD polymer modifications are supported.
932
+ */
895
933
  type: 'ccd';
896
934
  /**
897
935
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for
@@ -915,16 +953,24 @@ export declare namespace LibraryScreenListResultsResponse {
915
953
  */
916
954
  cyclic?: boolean;
917
955
  /**
918
- * Chemical modifications. Optional; defaults to an empty list when omitted.
956
+ * CCD chemical modifications. Optional; defaults to an empty list when omitted.
957
+ * SMILES modifications are not supported.
919
958
  */
920
959
  modifications?: Array<DnaEntity.Modification>;
921
960
  }
922
961
  namespace DnaEntity {
962
+ /**
963
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
964
+ * are not accepted.
965
+ */
923
966
  interface Modification {
924
967
  /**
925
968
  * 0-based index of the residue to modify
926
969
  */
927
970
  residue_index: number;
971
+ /**
972
+ * Modification format. Only CCD polymer modifications are supported.
973
+ */
928
974
  type: 'ccd';
929
975
  /**
930
976
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for
@@ -1206,17 +1252,24 @@ export declare namespace LibraryScreenStartResponse {
1206
1252
  */
1207
1253
  cyclic?: boolean;
1208
1254
  /**
1209
- * Post-translational modifications. Optional; defaults to an empty list when
1210
- * omitted.
1255
+ * CCD post-translational modifications. Optional; defaults to an empty list when
1256
+ * omitted. SMILES modifications are not supported.
1211
1257
  */
1212
1258
  modifications?: Array<ProteinEntityResponse.Modification>;
1213
1259
  }
1214
1260
  namespace ProteinEntityResponse {
1261
+ /**
1262
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
1263
+ * are not accepted.
1264
+ */
1215
1265
  interface Modification {
1216
1266
  /**
1217
1267
  * 0-based index of the residue to modify
1218
1268
  */
1219
1269
  residue_index: number;
1270
+ /**
1271
+ * Modification format. Only CCD polymer modifications are supported.
1272
+ */
1220
1273
  type: 'ccd';
1221
1274
  /**
1222
1275
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for
@@ -1240,16 +1293,24 @@ export declare namespace LibraryScreenStartResponse {
1240
1293
  */
1241
1294
  cyclic?: boolean;
1242
1295
  /**
1243
- * Chemical modifications. Optional; defaults to an empty list when omitted.
1296
+ * CCD chemical modifications. Optional; defaults to an empty list when omitted.
1297
+ * SMILES modifications are not supported.
1244
1298
  */
1245
1299
  modifications?: Array<RnaEntityResponse.Modification>;
1246
1300
  }
1247
1301
  namespace RnaEntityResponse {
1302
+ /**
1303
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
1304
+ * are not accepted.
1305
+ */
1248
1306
  interface Modification {
1249
1307
  /**
1250
1308
  * 0-based index of the residue to modify
1251
1309
  */
1252
1310
  residue_index: number;
1311
+ /**
1312
+ * Modification format. Only CCD polymer modifications are supported.
1313
+ */
1253
1314
  type: 'ccd';
1254
1315
  /**
1255
1316
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for
@@ -1273,16 +1334,24 @@ export declare namespace LibraryScreenStartResponse {
1273
1334
  */
1274
1335
  cyclic?: boolean;
1275
1336
  /**
1276
- * Chemical modifications. Optional; defaults to an empty list when omitted.
1337
+ * CCD chemical modifications. Optional; defaults to an empty list when omitted.
1338
+ * SMILES modifications are not supported.
1277
1339
  */
1278
1340
  modifications?: Array<DnaEntityResponse.Modification>;
1279
1341
  }
1280
1342
  namespace DnaEntityResponse {
1343
+ /**
1344
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
1345
+ * are not accepted.
1346
+ */
1281
1347
  interface Modification {
1282
1348
  /**
1283
1349
  * 0-based index of the residue to modify
1284
1350
  */
1285
1351
  residue_index: number;
1352
+ /**
1353
+ * Modification format. Only CCD polymer modifications are supported.
1354
+ */
1286
1355
  type: 'ccd';
1287
1356
  /**
1288
1357
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for
@@ -1724,17 +1793,24 @@ export declare namespace LibraryScreenStopResponse {
1724
1793
  */
1725
1794
  cyclic?: boolean;
1726
1795
  /**
1727
- * Post-translational modifications. Optional; defaults to an empty list when
1728
- * omitted.
1796
+ * CCD post-translational modifications. Optional; defaults to an empty list when
1797
+ * omitted. SMILES modifications are not supported.
1729
1798
  */
1730
1799
  modifications?: Array<ProteinEntityResponse.Modification>;
1731
1800
  }
1732
1801
  namespace ProteinEntityResponse {
1802
+ /**
1803
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
1804
+ * are not accepted.
1805
+ */
1733
1806
  interface Modification {
1734
1807
  /**
1735
1808
  * 0-based index of the residue to modify
1736
1809
  */
1737
1810
  residue_index: number;
1811
+ /**
1812
+ * Modification format. Only CCD polymer modifications are supported.
1813
+ */
1738
1814
  type: 'ccd';
1739
1815
  /**
1740
1816
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for
@@ -1758,16 +1834,24 @@ export declare namespace LibraryScreenStopResponse {
1758
1834
  */
1759
1835
  cyclic?: boolean;
1760
1836
  /**
1761
- * Chemical modifications. Optional; defaults to an empty list when omitted.
1837
+ * CCD chemical modifications. Optional; defaults to an empty list when omitted.
1838
+ * SMILES modifications are not supported.
1762
1839
  */
1763
1840
  modifications?: Array<RnaEntityResponse.Modification>;
1764
1841
  }
1765
1842
  namespace RnaEntityResponse {
1843
+ /**
1844
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
1845
+ * are not accepted.
1846
+ */
1766
1847
  interface Modification {
1767
1848
  /**
1768
1849
  * 0-based index of the residue to modify
1769
1850
  */
1770
1851
  residue_index: number;
1852
+ /**
1853
+ * Modification format. Only CCD polymer modifications are supported.
1854
+ */
1771
1855
  type: 'ccd';
1772
1856
  /**
1773
1857
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for
@@ -1791,16 +1875,24 @@ export declare namespace LibraryScreenStopResponse {
1791
1875
  */
1792
1876
  cyclic?: boolean;
1793
1877
  /**
1794
- * Chemical modifications. Optional; defaults to an empty list when omitted.
1878
+ * CCD chemical modifications. Optional; defaults to an empty list when omitted.
1879
+ * SMILES modifications are not supported.
1795
1880
  */
1796
1881
  modifications?: Array<DnaEntityResponse.Modification>;
1797
1882
  }
1798
1883
  namespace DnaEntityResponse {
1884
+ /**
1885
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
1886
+ * are not accepted.
1887
+ */
1799
1888
  interface Modification {
1800
1889
  /**
1801
1890
  * 0-based index of the residue to modify
1802
1891
  */
1803
1892
  residue_index: number;
1893
+ /**
1894
+ * Modification format. Only CCD polymer modifications are supported.
1895
+ */
1804
1896
  type: 'ccd';
1805
1897
  /**
1806
1898
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for
@@ -2103,17 +2195,24 @@ export declare namespace LibraryScreenEstimateCostParams {
2103
2195
  */
2104
2196
  cyclic?: boolean;
2105
2197
  /**
2106
- * Post-translational modifications. Optional; defaults to an empty list when
2107
- * omitted.
2198
+ * CCD post-translational modifications. Optional; defaults to an empty list when
2199
+ * omitted. SMILES modifications are not supported.
2108
2200
  */
2109
2201
  modifications?: Array<ProteinEntity.Modification>;
2110
2202
  }
2111
2203
  namespace ProteinEntity {
2204
+ /**
2205
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
2206
+ * are not accepted.
2207
+ */
2112
2208
  interface Modification {
2113
2209
  /**
2114
2210
  * 0-based index of the residue to modify
2115
2211
  */
2116
2212
  residue_index: number;
2213
+ /**
2214
+ * Modification format. Only CCD polymer modifications are supported.
2215
+ */
2117
2216
  type: 'ccd';
2118
2217
  /**
2119
2218
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for
@@ -2137,16 +2236,24 @@ export declare namespace LibraryScreenEstimateCostParams {
2137
2236
  */
2138
2237
  cyclic?: boolean;
2139
2238
  /**
2140
- * Chemical modifications. Optional; defaults to an empty list when omitted.
2239
+ * CCD chemical modifications. Optional; defaults to an empty list when omitted.
2240
+ * SMILES modifications are not supported.
2141
2241
  */
2142
2242
  modifications?: Array<RnaEntity.Modification>;
2143
2243
  }
2144
2244
  namespace RnaEntity {
2245
+ /**
2246
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
2247
+ * are not accepted.
2248
+ */
2145
2249
  interface Modification {
2146
2250
  /**
2147
2251
  * 0-based index of the residue to modify
2148
2252
  */
2149
2253
  residue_index: number;
2254
+ /**
2255
+ * Modification format. Only CCD polymer modifications are supported.
2256
+ */
2150
2257
  type: 'ccd';
2151
2258
  /**
2152
2259
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for
@@ -2170,16 +2277,24 @@ export declare namespace LibraryScreenEstimateCostParams {
2170
2277
  */
2171
2278
  cyclic?: boolean;
2172
2279
  /**
2173
- * Chemical modifications. Optional; defaults to an empty list when omitted.
2280
+ * CCD chemical modifications. Optional; defaults to an empty list when omitted.
2281
+ * SMILES modifications are not supported.
2174
2282
  */
2175
2283
  modifications?: Array<DnaEntity.Modification>;
2176
2284
  }
2177
2285
  namespace DnaEntity {
2286
+ /**
2287
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
2288
+ * are not accepted.
2289
+ */
2178
2290
  interface Modification {
2179
2291
  /**
2180
2292
  * 0-based index of the residue to modify
2181
2293
  */
2182
2294
  residue_index: number;
2295
+ /**
2296
+ * Modification format. Only CCD polymer modifications are supported.
2297
+ */
2183
2298
  type: 'ccd';
2184
2299
  /**
2185
2300
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for
@@ -2341,17 +2456,24 @@ export declare namespace LibraryScreenEstimateCostParams {
2341
2456
  */
2342
2457
  cyclic?: boolean;
2343
2458
  /**
2344
- * Post-translational modifications. Optional; defaults to an empty list when
2345
- * omitted.
2459
+ * CCD post-translational modifications. Optional; defaults to an empty list when
2460
+ * omitted. SMILES modifications are not supported.
2346
2461
  */
2347
2462
  modifications?: Array<ProteinEntity.Modification>;
2348
2463
  }
2349
2464
  namespace ProteinEntity {
2465
+ /**
2466
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
2467
+ * are not accepted.
2468
+ */
2350
2469
  interface Modification {
2351
2470
  /**
2352
2471
  * 0-based index of the residue to modify
2353
2472
  */
2354
2473
  residue_index: number;
2474
+ /**
2475
+ * Modification format. Only CCD polymer modifications are supported.
2476
+ */
2355
2477
  type: 'ccd';
2356
2478
  /**
2357
2479
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for
@@ -2375,16 +2497,24 @@ export declare namespace LibraryScreenEstimateCostParams {
2375
2497
  */
2376
2498
  cyclic?: boolean;
2377
2499
  /**
2378
- * Chemical modifications. Optional; defaults to an empty list when omitted.
2500
+ * CCD chemical modifications. Optional; defaults to an empty list when omitted.
2501
+ * SMILES modifications are not supported.
2379
2502
  */
2380
2503
  modifications?: Array<RnaEntity.Modification>;
2381
2504
  }
2382
2505
  namespace RnaEntity {
2506
+ /**
2507
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
2508
+ * are not accepted.
2509
+ */
2383
2510
  interface Modification {
2384
2511
  /**
2385
2512
  * 0-based index of the residue to modify
2386
2513
  */
2387
2514
  residue_index: number;
2515
+ /**
2516
+ * Modification format. Only CCD polymer modifications are supported.
2517
+ */
2388
2518
  type: 'ccd';
2389
2519
  /**
2390
2520
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for
@@ -2408,16 +2538,24 @@ export declare namespace LibraryScreenEstimateCostParams {
2408
2538
  */
2409
2539
  cyclic?: boolean;
2410
2540
  /**
2411
- * Chemical modifications. Optional; defaults to an empty list when omitted.
2541
+ * CCD chemical modifications. Optional; defaults to an empty list when omitted.
2542
+ * SMILES modifications are not supported.
2412
2543
  */
2413
2544
  modifications?: Array<DnaEntity.Modification>;
2414
2545
  }
2415
2546
  namespace DnaEntity {
2547
+ /**
2548
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
2549
+ * are not accepted.
2550
+ */
2416
2551
  interface Modification {
2417
2552
  /**
2418
2553
  * 0-based index of the residue to modify
2419
2554
  */
2420
2555
  residue_index: number;
2556
+ /**
2557
+ * Modification format. Only CCD polymer modifications are supported.
2558
+ */
2421
2559
  type: 'ccd';
2422
2560
  /**
2423
2561
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for
@@ -2693,17 +2831,24 @@ export declare namespace LibraryScreenStartParams {
2693
2831
  */
2694
2832
  cyclic?: boolean;
2695
2833
  /**
2696
- * Post-translational modifications. Optional; defaults to an empty list when
2697
- * omitted.
2834
+ * CCD post-translational modifications. Optional; defaults to an empty list when
2835
+ * omitted. SMILES modifications are not supported.
2698
2836
  */
2699
2837
  modifications?: Array<ProteinEntity.Modification>;
2700
2838
  }
2701
2839
  namespace ProteinEntity {
2840
+ /**
2841
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
2842
+ * are not accepted.
2843
+ */
2702
2844
  interface Modification {
2703
2845
  /**
2704
2846
  * 0-based index of the residue to modify
2705
2847
  */
2706
2848
  residue_index: number;
2849
+ /**
2850
+ * Modification format. Only CCD polymer modifications are supported.
2851
+ */
2707
2852
  type: 'ccd';
2708
2853
  /**
2709
2854
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for
@@ -2727,16 +2872,24 @@ export declare namespace LibraryScreenStartParams {
2727
2872
  */
2728
2873
  cyclic?: boolean;
2729
2874
  /**
2730
- * Chemical modifications. Optional; defaults to an empty list when omitted.
2875
+ * CCD chemical modifications. Optional; defaults to an empty list when omitted.
2876
+ * SMILES modifications are not supported.
2731
2877
  */
2732
2878
  modifications?: Array<RnaEntity.Modification>;
2733
2879
  }
2734
2880
  namespace RnaEntity {
2881
+ /**
2882
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
2883
+ * are not accepted.
2884
+ */
2735
2885
  interface Modification {
2736
2886
  /**
2737
2887
  * 0-based index of the residue to modify
2738
2888
  */
2739
2889
  residue_index: number;
2890
+ /**
2891
+ * Modification format. Only CCD polymer modifications are supported.
2892
+ */
2740
2893
  type: 'ccd';
2741
2894
  /**
2742
2895
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for
@@ -2760,16 +2913,24 @@ export declare namespace LibraryScreenStartParams {
2760
2913
  */
2761
2914
  cyclic?: boolean;
2762
2915
  /**
2763
- * Chemical modifications. Optional; defaults to an empty list when omitted.
2916
+ * CCD chemical modifications. Optional; defaults to an empty list when omitted.
2917
+ * SMILES modifications are not supported.
2764
2918
  */
2765
2919
  modifications?: Array<DnaEntity.Modification>;
2766
2920
  }
2767
2921
  namespace DnaEntity {
2922
+ /**
2923
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
2924
+ * are not accepted.
2925
+ */
2768
2926
  interface Modification {
2769
2927
  /**
2770
2928
  * 0-based index of the residue to modify
2771
2929
  */
2772
2930
  residue_index: number;
2931
+ /**
2932
+ * Modification format. Only CCD polymer modifications are supported.
2933
+ */
2773
2934
  type: 'ccd';
2774
2935
  /**
2775
2936
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for
@@ -2931,17 +3092,24 @@ export declare namespace LibraryScreenStartParams {
2931
3092
  */
2932
3093
  cyclic?: boolean;
2933
3094
  /**
2934
- * Post-translational modifications. Optional; defaults to an empty list when
2935
- * omitted.
3095
+ * CCD post-translational modifications. Optional; defaults to an empty list when
3096
+ * omitted. SMILES modifications are not supported.
2936
3097
  */
2937
3098
  modifications?: Array<ProteinEntity.Modification>;
2938
3099
  }
2939
3100
  namespace ProteinEntity {
3101
+ /**
3102
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
3103
+ * are not accepted.
3104
+ */
2940
3105
  interface Modification {
2941
3106
  /**
2942
3107
  * 0-based index of the residue to modify
2943
3108
  */
2944
3109
  residue_index: number;
3110
+ /**
3111
+ * Modification format. Only CCD polymer modifications are supported.
3112
+ */
2945
3113
  type: 'ccd';
2946
3114
  /**
2947
3115
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for
@@ -2965,16 +3133,24 @@ export declare namespace LibraryScreenStartParams {
2965
3133
  */
2966
3134
  cyclic?: boolean;
2967
3135
  /**
2968
- * Chemical modifications. Optional; defaults to an empty list when omitted.
3136
+ * CCD chemical modifications. Optional; defaults to an empty list when omitted.
3137
+ * SMILES modifications are not supported.
2969
3138
  */
2970
3139
  modifications?: Array<RnaEntity.Modification>;
2971
3140
  }
2972
3141
  namespace RnaEntity {
3142
+ /**
3143
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
3144
+ * are not accepted.
3145
+ */
2973
3146
  interface Modification {
2974
3147
  /**
2975
3148
  * 0-based index of the residue to modify
2976
3149
  */
2977
3150
  residue_index: number;
3151
+ /**
3152
+ * Modification format. Only CCD polymer modifications are supported.
3153
+ */
2978
3154
  type: 'ccd';
2979
3155
  /**
2980
3156
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for
@@ -2998,16 +3174,24 @@ export declare namespace LibraryScreenStartParams {
2998
3174
  */
2999
3175
  cyclic?: boolean;
3000
3176
  /**
3001
- * Chemical modifications. Optional; defaults to an empty list when omitted.
3177
+ * CCD chemical modifications. Optional; defaults to an empty list when omitted.
3178
+ * SMILES modifications are not supported.
3002
3179
  */
3003
3180
  modifications?: Array<DnaEntity.Modification>;
3004
3181
  }
3005
3182
  namespace DnaEntity {
3183
+ /**
3184
+ * Polymer residue modification. Only CCD codes are supported; SMILES modifications
3185
+ * are not accepted.
3186
+ */
3006
3187
  interface Modification {
3007
3188
  /**
3008
3189
  * 0-based index of the residue to modify
3009
3190
  */
3010
3191
  residue_index: number;
3192
+ /**
3193
+ * Modification format. Only CCD polymer modifications are supported.
3194
+ */
3011
3195
  type: 'ccd';
3012
3196
  /**
3013
3197
  * CCD code from RCSB PDB (e.g. 'MSE' for selenomethionine, 'SEP' for