@teselagen/ove 0.7.28 → 0.7.30-beta.1

package/alignmentTool.js

@@ -1,503 +0,0 @@
-import React from "react";
-import { Icon, Button, Intent, Classes, Callout } from "@blueprintjs/core";
-import {
-  FileUploadField,
-  TextareaField,
-  EditableTextField,
-  CheckboxField,
-  wrapDialog
-} from "@teselagen/ui";
-import { reduxForm, FieldArray } from "redux-form";
-import { anyToJson } from "@teselagen/bio-parsers";
-import { flatMap } from "lodash-es";
-import uniqid from "shortid";
-import { cloneDeep } from "lodash-es";
-import classNames from "classnames";
-
-import ToolbarItem from "./ToolbarItem";
-import { connectToEditor } from "../withEditorProps";
-import withEditorProps from "../withEditorProps";
-import { showDialog } from "../GlobalDialogUtils";
-import { compose } from "recompose";
-import { array_move } from "./array_move";
-
-export default connectToEditor(({ readOnly, toolBar = {} }) => {
-  return {
-    readOnly: readOnly,
-    isOpen: toolBar.openItem === "alignmentTool"
-  };
-})(({ toolbarItemProps, isOpen }) => {
-  return (
-    <ToolbarItem
-      {...{
-        Icon: <Icon data-test="alignmentTool" icon="align-left" />,
-        // toggled: alignmentTool.isOpen,
-        renderIconAbove: isOpen,
-        // onIconClick: toggleFindTool,
-        Dropdown: ConnectedAlignmentToolDropdown,
-        onIconClick: "toggleDropdown",
-        noDropdownIcon: true,
-        tooltip: isOpen ? "Hide Alignment Tool" : "Align to This Sequence",
-        ...toolbarItemProps
-      }}
-    />
-  );
-});
-
-class AlignmentToolDropdown extends React.Component {
-  render() {
-    const {
-      savedAlignments = [],
-      hasSavedAlignments,
-      toggleDropdown,
-      sequenceData
-    } = this.props;
-    return (
-      <div>
-        <Button
-          intent={Intent.PRIMARY}
-          onClick={() => {
-            toggleDropdown();
-            showDialog({
-              dialogType: "AlignmentToolDialog",
-              props: {
-                createNewAlignment: this.props.createNewAlignment,
-                upsertAlignmentRun: this.props.upsertAlignmentRun,
-                initialValues: {
-                  addedSequences: [{ ...sequenceData, isTemplate: true }]
-                }
-              }
-            });
-          }}
-        >
-          Create New Alignment
-        </Button>
-        <br></br>
-        <br></br>
-        <Callout intent="warning">
-          Note: This tool requires an alignment server to be hooked up for it to
-          work properly. It will NOT work in the OVE demo page.
-        </Callout>
-        <div className="vespacer" />
-        {hasSavedAlignments && (
-          <div>
-            <h6>Saved Alignments:</h6>
-            {!savedAlignments.length && (
-              <div style={{ fontStyle: "italic" }}> No Alignments</div>
-            )}
-            {savedAlignments.map((savedAlignment, i) => {
-              return <div key={i}>Saved Alignment {i}</div>;
-            })}
-          </div>
-        )}
-      </div>
-    );
-  }
-}
-const ConnectedAlignmentToolDropdown = withEditorProps(AlignmentToolDropdown);
-
-class AlignmentTool extends React.Component {
-  state = {
-    templateSeqIndex: 0
-  };
-  sendSelectedDataToBackendForAlignment = async values => {
-    const {
-      addedSequences,
-      isPairwiseAlignment,
-      isAlignToRefSeq,
-      isAutotrimmedSeq
-    } = values;
-    const {
-      hideModal,
-      /* onAlignmentSuccess, */ createNewAlignment,
-      // createNewMismatchesList,
-      upsertAlignmentRun
-    } = this.props;
-    const { templateSeqIndex } = this.state;
-    const addedSequencesToUse = array_move(addedSequences, templateSeqIndex, 0);
-
-    let addedSequencesToUseTrimmed;
-    if (isAutotrimmedSeq) {
-      addedSequencesToUseTrimmed = cloneDeep(addedSequencesToUse);
-      // trimming any sequences with chromatogram data
-      for (let i = 0; i < addedSequencesToUseTrimmed.length; i++) {
-        if ("chromatogramData" in addedSequencesToUseTrimmed[i]) {
-          // if (addedSequencesToUseTrimmed[i].chromatogramData.qualNums) {
-          if ("qualNums" in addedSequencesToUseTrimmed[i].chromatogramData) {
-            // returning bp pos for { suggestedTrimStart, suggestedTrimEnd }
-            const { suggestedTrimStart, suggestedTrimEnd } = mottTrim(
-              addedSequencesToUseTrimmed[i].chromatogramData.qualNums
-            );
-            addedSequencesToUseTrimmed[i].sequence = addedSequencesToUseTrimmed[
-              i
-            ].sequence.slice(suggestedTrimStart, suggestedTrimEnd + 1);
-            const elementsToTrim = ["baseCalls", "basePos", "qualNums"];
-            // eslint-disable-next-line no-unused-vars
-            for (const element in addedSequencesToUseTrimmed[i]
-              .chromatogramData) {
-              if (elementsToTrim.indexOf(element) !== -1) {
-                addedSequencesToUseTrimmed[i].chromatogramData[element] =
-                  addedSequencesToUseTrimmed[i].chromatogramData[element].slice(
-                    suggestedTrimStart,
-                    suggestedTrimEnd + 1
-                  );
-              }
-            }
-          }
-        }
-      }
-    }
-    let seqsToAlign;
-    if (addedSequencesToUseTrimmed) {
-      seqsToAlign = addedSequencesToUseTrimmed;
-    } else {
-      seqsToAlign = addedSequencesToUse;
-    }
-
-    hideModal();
-    const alignmentId = uniqid();
-    // const alignmentIdMismatches = uniqid();
-    createNewAlignment({
-      id: alignmentId,
-      name: seqsToAlign[0].name + " Alignment"
-    });
-    //set the alignment to loading
-    upsertAlignmentRun({
-      id: alignmentId,
-      loading: true
-    });
-    // createNewMismatchesList({
-    //   id: alignmentIdMismatches,
-    //   name: addedSequencesToUse[0].name + " Mismatches",
-    //   alignmentId: alignmentId
-    // });
-
-    // const j5server = process.env.REMOTE_J5 || "http://j5server.teselagen.com"
-
-    window.toastr.success("Alignment submitted.");
-    const replaceProtocol = url => {
-      return url.replace("http://", window.location.protocol + "//");
-    };
-
-    const seqInfoToSend = seqsToAlign.map(({ sequence, name, id }) => {
-      return {
-        sequence,
-        name,
-        id
-      };
-    });
-
-    const {
-      alignedSequences: _alignedSequences,
-      pairwiseAlignments,
-      alignmentsToRefSeq
-    } = await (
-      await fetch({
-        url: replaceProtocol("http://j5server.teselagen.com/alignment/run"),
-        method: "post",
-        body: JSON.stringify({
-          //only send over the bear necessities :)
-          sequencesToAlign: seqInfoToSend,
-          isPairwiseAlignment,
-          isAlignToRefSeq
-        })
-      })
-    ).json();
-
-    // alignmentsToRefSeq set to alignedSequences for now
-    let alignedSequences = _alignedSequences;
-    if (alignmentsToRefSeq) {
-      alignedSequences = alignmentsToRefSeq;
-    }
-    if (!alignedSequences && !pairwiseAlignments)
-      window.toastr.error("Error running sequence alignment!");
-    //set the alignment to loading
-    upsertAlignmentRun({
-      id: alignmentId,
-      pairwiseAlignments:
-        pairwiseAlignments &&
-        pairwiseAlignments.map((alignedSequences, topIndex) => {
-          return alignedSequences.map((alignmentData, innerIndex) => {
-            return {
-              sequenceData: seqsToAlign[innerIndex > 0 ? topIndex + 1 : 0],
-              alignmentData,
-              chromatogramData: seqsToAlign[innerIndex].chromatogramData
-            };
-          });
-        }),
-      alignmentTracks:
-        alignedSequences &&
-        alignedSequences.map(alignmentData => {
-          return {
-            sequenceData:
-              seqsToAlign[
-                alignmentData.name.slice(0, alignmentData.name.indexOf("_"))
-              ],
-            alignmentData,
-            chromatogramData:
-              seqsToAlign[
-                alignmentData.name.slice(0, alignmentData.name.indexOf("_"))
-              ].chromatogramData
-          };
-        })
-      // alignmentTracks:
-      //   alignedSequences &&
-      //   alignedSequences.map((alignmentData, i) => {
-      //     return {
-      //       sequenceData: addedSequencesToUse[i],
-      //       alignmentData,
-      //       chromatogramData: addedSequencesToUse[i].chromatogramData
-      //     };
-      //   })
-    });
-  };
-
-  handleFileUpload = (files, onChange) => {
-    const { array } = this.props;
-    flatMap(files, async file => {
-      const results = await anyToJson(file.originalFileObj, {
-        fileName: file.name,
-        acceptParts: true
-      });
-      return results.forEach(result => {
-        if (result.success) {
-          array.push("addedSequences", result.parsedSequence);
-        } else {
-          return window.toastr.warning("Error parsing file: ", file.name);
-        }
-      });
-    });
-    onChange([]);
-  };
-  renderAddSequence = ({ fields, templateSeqIndex }) => {
-    const { handleSubmit } = this.props;
-
-    const sequencesToAlign = fields.getAll() || [];
-    return (
-      <div>
-        <h6>Or enter sequences in plain text format</h6>
-        <div>
-          <AddYourOwnSeqForm
-            addSeq={newSeq => {
-              fields.push(newSeq);
-            }}
-          />
-          <h6 style={{ marginTop: 15 }}>Sequences To Align: </h6>
-          {!fields.getAll() && <div>No sequences added yet.</div>}
-          <div
-            style={{ maxHeight: 180, overflowY: "auto" }}
-            className="veAlignmentToolSelectedSequenceList"
-          >
-            {sequencesToAlign.map((addedSeq, index) => {
-              return (
-                <div
-                  onClick={() => {
-                    this.setState({
-                      templateSeqIndex: index
-                    });
-                  }}
-                  style={{
-                    borderBottom: "1px solid lightgrey",
-                    paddingBottom: 4,
-                    marginBottom: 4,
-                    width: "100%",
-                    justifyContent: "space-between",
-                    alignItems: "center",
-                    display: "flex"
-                  }}
-                  key={index}
-                >
-                  <div>
-                    {addedSeq.name}{" "}
-                    <span style={{ fontSize: 10 }}>
-                      {" "}
-                      ({addedSeq.sequence.length} bps)
-                    </span>
-                  </div>
-                  {index === templateSeqIndex && (
-                    <div
-                      className={classNames(
-                        Classes.TAG,
-                        Classes.ROUND,
-                        Classes.INTENT_PRIMARY
-                      )}
-                    >
-                      template
-                    </div>
-                  )}
-
-                  <Button
-                    onClick={e => {
-                      e.stopPropagation();
-                      e.preventDefault();
-                      fields.remove(index);
-                      if (index === templateSeqIndex) {
-                        this.setState({ templateSeqIndex: 0 });
-                      }
-                    }}
-                  >
-                    Remove
-                  </Button>
-                </div>
-              );
-            })}
-          </div>
-          <br />
-          <CheckboxField
-            name="isPairwiseAlignment"
-            style={{ display: "flex", alignItems: "center" }}
-            label={
-              <div>
-                Create Pairwise Alignment{" "}
-                <span style={{ fontSize: 11 }}>
-                  Individually align each uploaded file against the template
-                  sequence (instead of creating a single Multiple Sequence
-                  Alignment)
-                </span>
-              </div>
-            }
-          />
-          <CheckboxField
-            name="isAlignToRefSeq"
-            style={{ display: "flex", alignItems: "center" }}
-            label={
-              <div>
-                Align Sequencing Reads to Reference Sequence{" "}
-                <span style={{ fontSize: 11 }}>
-                  Align short sequencing reads to a long reference sequence
-                </span>
-              </div>
-            }
-          />
-          <CheckboxField
-            name="isAutotrimmedSeq"
-            style={{ display: "flex", alignItems: "center" }}
-            label={
-              <div>
-                Auto-Trim Sequences{" "}
-                <span style={{ fontSize: 11 }}>
-                  Automatically trim low-quality ends of sequences based on
-                  quality scores
-                </span>
-              </div>
-            }
-          />
-
-          <Button
-            style={{ marginTop: 15, float: "right" }}
-            intent={Intent.PRIMARY}
-            disabled={sequencesToAlign.length < 2}
-            onClick={handleSubmit(this.sendSelectedDataToBackendForAlignment)}
-          >
-            Create alignment
-          </Button>
-        </div>
-      </div>
-    );
-  };
-
-  render() {
-    const { selectFromSequenceLibraryHook } = this.props;
-    const { templateSeqIndex } = this.state;
-    return (
-      <div style={{ padding: 20 }} className="veAlignmentTool">
-        <h6>Upload files you'd like to align (.ab1, .fasta, .gb) </h6>
-        <FileUploadField
-          name="alignmentToolSequenceUpload"
-          style={{ maxWidth: 400 }}
-          beforeUpload={this.handleFileUpload}
-        />
-        {selectFromSequenceLibraryHook && (
-          <h6>Or Select from your sequence library </h6>
-        )}
-
-        <FieldArray
-          name="addedSequences"
-          templateSeqIndex={templateSeqIndex}
-          component={this.renderAddSequence}
-        />
-      </div>
-    );
-  }
-}
-
-export const AlignmentToolDialog = compose(
-  wrapDialog({ title: "Create New Alignment" }),
-  reduxForm({
-    form: "veAlignmentTool"
-  })
-)(AlignmentTool);
-
-const AddYourOwnSeqForm = reduxForm({
-  form: "AddYourOwnSeqForm",
-  validate: ({ name, sequence }) => {
-    const errors = {};
-    if (!name) {
-      errors.name = "Required";
-    }
-    if (!sequence) {
-      errors.sequence = "Required";
-    }
-    return errors;
-  }
-})(({ pristine, error, handleSubmit, reset, addSeq }) => {
-  return (
-    <form
-      onSubmit={handleSubmit(vals => {
-        reset();
-        addSeq(vals);
-      })}
-    >
-      <EditableTextField
-        style={{ maxWidth: 200 }}
-        placeholder="Untitled Sequence"
-        name="name"
-      />
-      <TextareaField
-        style={{ maxWidth: 400 }}
-        placeholder="AGTTGAGC"
-        name="sequence"
-      />
-      <Button disabled={pristine || error} type="submit">
-        Add
-      </Button>
-    </form>
-  );
-});
-
-function mottTrim(qualNums) {
-  if (!qualNums) return;
-  let startPos = 0;
-  let endPos = 0;
-  const totalScoreInfo = [];
-  let score = 0;
-  let totalScore = 0;
-  const cutoff = 0.05;
-  for (let i = 0; i < qualNums.length; i++) {
-    // low-quality bases have high error probabilities, so may have a negative base score
-    score = cutoff - Math.pow(10, qualNums[i] / -10);
-    totalScore += score;
-    totalScoreInfo.push(totalScore);
-    // score = score + cutoff - Math.pow(10, qualNums[i] / -10);
-    // if (totalScore < 0) {
-    //   tempStart = i;
-    // }
-    // if (i - tempStart > endPos - startPos) {
-    //   startPos = tempStart;
-    //   endPos = i;
-    // }
-    if (totalScore < 0) {
-      totalScore = 0;
-    }
-  }
-  const firstPositiveValue = totalScoreInfo.find(e => {
-    return e > 0;
-  });
-  startPos = totalScoreInfo.indexOf(firstPositiveValue);
-  const highestValue = Math.max(...totalScoreInfo);
-  endPos = totalScoreInfo.lastIndexOf(highestValue);
-  return {
-    suggestedTrimStart: startPos,
-    suggestedTrimEnd: endPos
-  };
-}