@sjcrh/proteinpaint-client 2.219.1 → 2.221.0

package/dist/chunk-FZYVPRVQ.js

@@ -0,0 +1,38 @@
+import {
+  plotColor
+} from "./chunk-WJLRU5OF.js";
+
+// plots/violin/settings/defaults.ts
+function getDefaultViolinSettings(app, overrides = {}) {
+  const defaults = {
+    orientation: "horizontal",
+    rowlabelw: 250,
+    brushRange: null,
+    //object with start and end if there is a brush selection
+    svgw: 500,
+    // span length of a plot/svg, not including margin
+    datasymbol: "rug",
+    radius: 10,
+    axisHeight: 60,
+    rightMargin: 50,
+    lines: [],
+    isLogScale: false,
+    // false: linear scale, true: log scale
+    rowSpace: 10,
+    medianLength: 7,
+    medianColor: "#FF0000",
+    medianThickness: 3,
+    ticks: 15,
+    defaultColor: plotColor,
+    method: 0,
+    orderByMedian: false,
+    showStats: true,
+    showAssociationTests: true
+  };
+  return Object.assign(defaults, overrides);
+}
+
+export {
+  getDefaultViolinSettings
+};
+//# sourceMappingURL=chunk-FZYVPRVQ.js.map

package/dist/chunk-GBKQHVKJ.js

@@ -0,0 +1,274 @@
+import {
+  termType2label
+} from "./chunk-JHLF2ZC2.js";
+import {
+  TermTypes
+} from "./chunk-WJLRU5OF.js";
+import {
+  __export
+} from "./chunk-HS5PO5ZQ.js";
+
+// plots/matrix/hierCluster.renderers.js
+var hierCluster_renderers_exports = {};
+__export(hierCluster_renderers_exports, {
+  maySetSandboxHeader: () => maySetSandboxHeader,
+  plotDendrogramHclust: () => plotDendrogramHclust,
+  renderImage: () => renderImage
+});
+function maySetSandboxHeader(appState) {
+  if (!this.dom.header) return;
+  const dataType = this.config.dataType;
+  const headerText = this.config?.headerText ? `${this.config.headerText} ` : "";
+  let title;
+  if (this.config.preBuiltPlotTitle) {
+    title = this.config.preBuiltPlotTitle;
+  } else if (this.config.appName) {
+    title = `${headerText}${this.config.appName} Clustering`;
+  } else if (dataType == TermTypes.PROTEOME_ABUNDANCE) {
+    title = this.config.assayCohortTitle ? `Protein Abundance Clustering (${this.config.assayCohortTitle})` : "Protein Abundance Clustering";
+  } else {
+    title = `${headerText}${termType2label(dataType)} Clustering`;
+  }
+  this.dom.header.text(title);
+}
+function plotDendrogramHclust(plotOnly) {
+  const d = this.dimensions;
+  const s = this.config.settings.matrix;
+  const xOffset = d.seriesXoffset;
+  const pxr = window.devicePixelRatio <= 1 ? 1 : window.devicePixelRatio;
+  const obj = this.hierClusterData.clustering;
+  const row = obj.row;
+  const col = obj.col;
+  const rowHeight = this.settings.matrix.clusterRowh, { xDendrogramHeight, yDendrogramHeight } = this.settings.hierCluster, colWidth = this.dimensions.dx;
+  if (plotOnly !== "left") {
+    if (!this.settings.hierCluster.clusterSamples) {
+      this.dom.topDendrogram.selectAll("*").remove();
+    } else {
+      const height2px = getHclustHeightScalefactor(col.height, yDendrogramHeight);
+      const height = yDendrogramHeight + 1e-7;
+      const width = Math.min(colWidth * col.inputOrder.length, s.imgWMax);
+      if (width <= 0 || height <= 0) {
+        console.warn(
+          "Skipping top dendrogram render: invalid dimensions.",
+          "This may indicate a zoom feedback loop issue.",
+          {
+            width,
+            height,
+            colWidth,
+            sampleCount: col.inputOrder.length,
+            yDendrogramHeight
+          }
+        );
+        this.dom.topDendrogram.selectAll("*").remove();
+        return;
+      }
+      const canvas = new OffscreenCanvas(width * pxr, height * pxr);
+      const ctx = canvas.getContext("2d");
+      ctx.scale(pxr, pxr);
+      ctx.translate(-d.xMin, 0);
+      ctx.imageSmoothingEnabled = false;
+      ctx.imageSmoothingQuality = "high";
+      ctx.strokeStyle = "black";
+      const mergedClusters = /* @__PURE__ */ new Map();
+      for (const [clusterid0, pair] of col.merge.entries()) {
+        const clusterid = clusterid0 + 1;
+        const children = [];
+        const childrenClusters = [];
+        let x1, x2, y1, y2;
+        if (pair.n1 < 0) {
+          const [name, columnNumber] = getLeafNumber(pair.n1, col.inputOrder, col.order);
+          x1 = colWidth * (columnNumber + 0.5);
+          y1 = yDendrogramHeight;
+          children.push({ name });
+        } else {
+          if (!mergedClusters.has(pair.n1)) throw "pair.n1 is positive but not seen before";
+          const c = mergedClusters.get(pair.n1);
+          x1 = c.x;
+          y1 = c.y;
+          children.push(...c.children);
+          childrenClusters.push(pair.n1);
+        }
+        if (pair.n2 < 0) {
+          const [name, columnNumber] = getLeafNumber(pair.n2, col.inputOrder, col.order);
+          x2 = colWidth * (columnNumber + 0.5);
+          y2 = yDendrogramHeight;
+          children.push({ name });
+        } else {
+          if (!mergedClusters.has(pair.n2)) throw "pair.n1 is positive but not seen before";
+          const c = mergedClusters.get(pair.n2);
+          x2 = c.x;
+          y2 = c.y;
+          children.push(...c.children);
+          childrenClusters.push(pair.n2);
+        }
+        const clusterY = yDendrogramHeight - col.height[clusterid0].height * height2px;
+        const highlight = this.clickedClusterIds?.includes(clusterid);
+        ctx.strokeStyle = highlight ? "red" : "black";
+        ctx.beginPath();
+        ctx.moveTo(x1, y1);
+        ctx.lineTo(x1, clusterY);
+        ctx.lineTo(x2, clusterY);
+        ctx.lineTo(x2, y2);
+        ctx.stroke();
+        ctx.closePath();
+        mergedClusters.set(clusterid, {
+          x: (x1 + x2) / 2,
+          y: clusterY,
+          children,
+          childrenClusters,
+          clusterPosition: {
+            x1,
+            x2,
+            y1,
+            y2,
+            clusterY
+          }
+        });
+      }
+      this.renderImage(
+        this.api,
+        this.dom.topDendrogram,
+        canvas,
+        width,
+        height,
+        xDendrogramHeight + 0.5 * colWidth + d.xMin,
+        s.margin.top + s.scrollHeight
+      );
+      col.mergedClusters = mergedClusters;
+    }
+  }
+  if (plotOnly !== "top") {
+    if (!this.settings.hierCluster.clusterRows) {
+      this.dom.leftDendrogram.selectAll("*").remove();
+    } else {
+      const height2px = getHclustHeightScalefactor(row.height, xDendrogramHeight);
+      const width = xDendrogramHeight + 1e-7;
+      const height = rowHeight * row.inputOrder.length;
+      const canvasWidthPx = Number.isFinite(width) && Number.isFinite(pxr) ? Math.max(0, Math.floor(width * pxr)) : 0;
+      const canvasHeightPx = Number.isFinite(height) && Number.isFinite(pxr) ? Math.max(0, Math.floor(height * pxr)) : 0;
+      if (!Number.isFinite(width) || !Number.isFinite(height) || !Number.isFinite(pxr) || width <= 0 || height <= 0 || pxr <= 0 || canvasWidthPx < 1 || canvasHeightPx < 1) {
+        console.warn(
+          "Skipping left dendrogram render: invalid dimensions.",
+          "This may indicate a zoom feedback loop issue.",
+          {
+            width,
+            height,
+            pxr,
+            canvasWidthPx,
+            canvasHeightPx,
+            rowHeight,
+            termCount: row.inputOrder.length,
+            xDendrogramHeight
+          }
+        );
+        this.dom.leftDendrogram.selectAll("*").remove();
+        return;
+      }
+      const canvas = new OffscreenCanvas(canvasWidthPx, canvasHeightPx);
+      const ctx = canvas.getContext("2d");
+      ctx.scale(pxr, pxr);
+      ctx.imageSmoothingEnabled = false;
+      ctx.imageSmoothingQuality = "high";
+      ctx.strokeStyle = "black";
+      const mergedClusters = /* @__PURE__ */ new Map();
+      for (const [clusterid0, pair] of row.merge.entries()) {
+        const clusterid = clusterid0 + 1;
+        const children = [];
+        const childrenClusters = [];
+        let x1, x2, y1, y2;
+        if (pair.n1 < 0) {
+          const [name, rowNumber] = getLeafNumber(pair.n1, row.inputOrder, row.order);
+          y1 = rowHeight * (rowNumber + 0.5);
+          x1 = xDendrogramHeight;
+          children.push({ name });
+        } else {
+          if (!mergedClusters.has(pair.n1)) throw "pair.n1 is positive but not seen before";
+          const c = mergedClusters.get(pair.n1);
+          x1 = c.x;
+          y1 = c.y;
+          children.push(...c.children);
+          childrenClusters.push(pair.n1);
+        }
+        if (pair.n2 < 0) {
+          const [name, rowNumber] = getLeafNumber(pair.n2, row.inputOrder, row.order);
+          y2 = rowHeight * (rowNumber + 0.5);
+          x2 = xDendrogramHeight;
+          children.push({ name });
+        } else {
+          if (!mergedClusters.has(pair.n2)) throw "pair.n1 is positive but not seen before";
+          const c = mergedClusters.get(pair.n2);
+          x2 = c.x;
+          y2 = c.y;
+          children.push(...c.children);
+          childrenClusters.push(pair.n2);
+        }
+        const clusterX = xDendrogramHeight - row.height[clusterid0].height * height2px;
+        const highlight = this.clickedLeftClusterIds?.includes(clusterid);
+        ctx.strokeStyle = highlight ? "red" : "black";
+        ctx.beginPath();
+        ctx.moveTo(x1, y1);
+        ctx.lineTo(clusterX, y1);
+        ctx.lineTo(clusterX, y2);
+        ctx.lineTo(x2, y2);
+        ctx.stroke();
+        ctx.closePath();
+        mergedClusters.set(clusterid, {
+          x: clusterX,
+          y: (y1 + y2) / 2,
+          children,
+          childrenClusters,
+          clusterPosition: {
+            x1,
+            x2,
+            y1,
+            y2,
+            clusterX
+          }
+        });
+      }
+      const t = this.termOrder.find((t2) => t2.grp.type == "hierCluster" || t2.grp.name == this.hcTermGroup.name);
+      const y = (
+        // t.labelOffset is commented out because it is already handled in adjustSvgDimensions
+        t.grpIndex * s.rowgspace + t.prevGrpTotalIndex * s.rowh + t.totalHtAdjustments + s.margin.top + s.scrollHeight + // left dendrogram image must be lower than the top dendrogram image height
+        yDendrogramHeight
+      );
+      this.renderImage(this.api, this.dom.leftDendrogram, canvas, width, height, 0, y);
+      row.mergedClusters = mergedClusters;
+    }
+  }
+}
+async function renderImage(componentApi, g, canvas, width, height, x, y) {
+  const sequenceId = componentApi.getSequenceId();
+  const reader = new FileReader();
+  reader.addEventListener(
+    "load",
+    () => {
+      if (componentApi.isStaleSequenceId(sequenceId)) return;
+      g.selectAll("*").remove();
+      g.append("image").attr("x", x + 0.033).attr("y", y + 0.033).attr("xlink:href", reader.result).attr("width", width).attr("height", height);
+    },
+    false
+  );
+  const blob = await canvas.convertToBlob({ quality: 1 });
+  reader.readAsDataURL(blob);
+}
+function getHclustHeightScalefactor(lst, ph) {
+  let max = lst[0].height;
+  for (const h of lst) max = Math.max(max, h.height);
+  return ph / max;
+}
+function getLeafNumber(minus, inputOrder, order) {
+  const name = inputOrder[-minus - 1];
+  if (!name) throw "minus not in inputOrder";
+  const i = order.findIndex((j) => j.name == name);
+  if (i == -1) throw "name not found in hc$order";
+  return [name, i];
+}
+
+export {
+  maySetSandboxHeader,
+  plotDendrogramHclust,
+  renderImage,
+  hierCluster_renderers_exports
+};
+//# sourceMappingURL=chunk-GBKQHVKJ.js.map

package/dist/chunk-GUW7VTUL.js

@@ -0,0 +1,281 @@
+import {
+  getMclassSorter,
+  getSampleGroupSorter,
+  getSampleSorter,
+  getTermSorter
+} from "./chunk-5DI4UNH5.js";
+import {
+  setRelatedSamples
+} from "./chunk-C2MCQZWH.js";
+import {
+  filterVariantValues,
+  sample_match_termvaluesetting
+} from "./chunk-MHWYRNGA.js";
+import {
+  dtcnv,
+  dtfusionrna,
+  dtgeneexpression,
+  dtsnvindel
+} from "./chunk-WJLRU5OF.js";
+import {
+  __export
+} from "./chunk-HS5PO5ZQ.js";
+
+// plots/matrix/matrix.groups.js
+var matrix_groups_exports = {};
+__export(matrix_groups_exports, {
+  classifyValues: () => classifyValues,
+  getSampleGroups: () => getSampleGroups,
+  getSampleOrder: () => getSampleOrder,
+  getTermOrder: () => getTermOrder,
+  stackSiblingCellsByClass: () => stackSiblingCellsByClass
+});
+function getTermOrder(data) {
+  const s = this.settings.matrix;
+  this.termSorter = getTermSorter(this, s);
+  const termOrder = [];
+  let totalIndex = 0, visibleGrpIndex = 0, numClusterTerms = 0;
+  this.mclassSorter = getMclassSorter(this);
+  this.samplesByAncestorId = /* @__PURE__ */ new Map();
+  const seenAncestorSamples = /* @__PURE__ */ new Set();
+  for (const sd of data.lst) {
+    if (seenAncestorSamples.has(sd.sample)) continue;
+    seenAncestorSamples.add(sd.sample);
+    if (!sd._ref_?.ancestors) continue;
+    for (const a of sd._ref_.ancestors) {
+      const id = a.ancestor_id;
+      if (id === void 0) continue;
+      if (!this.samplesByAncestorId.has(id)) this.samplesByAncestorId.set(id, /* @__PURE__ */ new Set());
+      this.samplesByAncestorId.get(id).add(sd);
+    }
+  }
+  for (const [grpIndex, grp] of this.termGroups.entries()) {
+    const lst = [];
+    for (const [index, tw] of grp.lst.entries()) {
+      const counts = { samples: 0, hits: 0 };
+      const countedSamples = /* @__PURE__ */ new Set();
+      for (const sd of data.lst) {
+        if (countedSamples.has(sd.sample)) continue;
+        countedSamples.add(sd.sample);
+        const anno = sd[tw.$id];
+        if (anno) {
+          const { filteredValues, countedValues, renderedValues } = this.classifyValues(anno, tw, grp, s, sd);
+          anno.filteredValues = filteredValues;
+          anno.countedValues = countedValues;
+          anno.renderedValues = renderedValues;
+          if (anno.countedValues?.length) {
+            const v = tw.term.values?.[anno.value];
+            if (v?.uncountable) continue;
+            counts.samples += 1;
+            counts.hits += anno.countedValues.length;
+            if (tw.q?.mode == "continuous") {
+              const v2 = anno.value;
+              if (!("minval" in counts) || counts.minval > v2) counts.minval = v2;
+              if (!("maxval" in counts) || counts.maxval < v2) counts.maxval = v2;
+            }
+          }
+        }
+      }
+      if (grp.type != "hierCluster" || counts.samples) lst.push({ tw, counts, index });
+      if (grp.type == "hierCluster") numClusterTerms++;
+    }
+    const termSorter = grp.sortTermsBy || grp.type == "hierCluster" ? getTermSorter(this, s, grp) : this.termSorter;
+    const processedLst = lst.filter((t) => {
+      if ("minNumSamples" in t.tw) return t.tw.minNumSamples <= t.counts.samples;
+      if (!grp.settings) return true;
+      return !("minNumSamples" in grp.settings) || t.counts.samples >= grp.settings.minNumSamples;
+    }).sort(termSorter);
+    if (!processedLst.length) continue;
+    for (const [index, t] of processedLst.entries()) {
+      const { tw, counts } = t;
+      const ref = data.refs.byTermId[t.tw.$id] || {};
+      termOrder.push({
+        grp,
+        grpIndex,
+        visibleGrpIndex,
+        tw,
+        index,
+        // rendered index
+        lstIndex: t.index,
+        // as-listed index, before applying term filters
+        processedLst,
+        prevGrpTotalIndex: totalIndex,
+        totalIndex: totalIndex + index,
+        ref,
+        allCounts: counts
+        // note: term label will be assigned after sample counts are known
+        // label: t.tw.label || t.tw.term.name,
+      });
+    }
+    totalIndex += processedLst.length;
+    visibleGrpIndex += 1;
+  }
+  for (const [ancestor_id, samples] of this.samplesByAncestorId.entries()) {
+    if (samples.size < 2) this.samplesByAncestorId.delete(ancestor_id);
+  }
+  this.numTerms = termOrder.length;
+  this.numClusterTerms = numClusterTerms;
+  return termOrder;
+}
+function getSampleGroups(data) {
+  const s = this.settings.matrix;
+  const defaultSampleGrp = {
+    id: this.config.divideBy?.$id,
+    name: this.config.divideBy ? "Not annotated" : "",
+    lst: []
+  };
+  const sampleGroups = /* @__PURE__ */ new Map();
+  const term = this.config.divideBy?.term || {};
+  const $id = this.config.divideBy?.$id || "-";
+  const exclude = this.config.divideBy?.exclude || [];
+  const values = term.values || {};
+  const ref = data.refs.byTermId[$id] || {};
+  for (const row of data.lst) {
+    if ($id in row) {
+      const cell = row[$id];
+      const keys = term.type == "multivalue" && Array.isArray(cell.values) ? cell.values.map((v) => v.key) : [cell.key];
+      for (const key of keys) {
+        const name = key in values && values[key].label ? values[key].label : key;
+        if (!sampleGroups.has(key)) {
+          const grp = {
+            name: `${name}`,
+            // convert to a string
+            id: key,
+            lst: [],
+            tw: this.config.divideBy,
+            legendGroups: {},
+            isExcluded: exclude.includes(key)
+          };
+          if (ref.bins && s.sortSampleGrpsBy == "name") grp.order = ref.bins.findIndex((bin) => bin.name == key);
+          else delete grp.order;
+          sampleGroups.set(key, grp);
+        }
+        sampleGroups.get(key).lst.push(row);
+      }
+    } else {
+      defaultSampleGrp.lst.push(row);
+    }
+  }
+  const sampleGrpsArr = [...sampleGroups.values()];
+  const n = sampleGroups.size;
+  if (n > 100 && sampleGrpsArr.filter((sg) => sg.lst.length < 3).length > 0.8 * n) {
+    const l = s.controlLabels;
+    throw `Did not group ${l.samples} by "${term.name}": too many ${l.sample} groups (${n}), with the majority of groups having <= 2 ${l.samples} per group.`;
+  }
+  if (defaultSampleGrp.lst.length && !sampleGroups.size) {
+    sampleGroups.set(void 0, defaultSampleGrp);
+    sampleGrpsArr.push(...sampleGroups.values());
+  }
+  this.asListedSampleOrder = [];
+  for (const grp of sampleGrpsArr) {
+    this.asListedSampleOrder.push(...grp.lst.map((s2) => s2.sample));
+  }
+  const selectedDictTerms = this.termOrder.filter((t) => t.tw.sortSamples && t.tw.term.type != "geneVariant");
+  const noGrpSampleSorter = getSampleSorter(this, s, data.lst, {
+    skipSorter: (p, tw) => !p.types?.includes("geneVariant") && selectedDictTerms.find((t) => t.tw.$id === tw.$id)
+  });
+  const noGrpSampleOrder = data.lst.sort(noGrpSampleSorter);
+  const allowedSamples = noGrpSampleOrder.slice(0, s.maxSample);
+  const dataFilter = (d) => allowedSamples.includes(d);
+  const hitsPerSample = (t, c) => t + (typeof c == "object" && c.countedValues?.length ? 1 : 0);
+  const countHits = (total, d) => total + (Object.values(d).reduce(hitsPerSample, 0) ? 1 : 0);
+  const grpLstSampleSorter = getSampleSorter(this, s, data.lst);
+  for (const grp of sampleGrpsArr) {
+    grp.lst = grp.lst.filter(dataFilter);
+    grp.totalCountedValues = grp.lst.reduce(countHits, 0);
+    grp.lst.sort(grpLstSampleSorter);
+    if (this.config.chartType == "matrix" && s.sortBySampleAncestry) setRelatedSamples(grp);
+  }
+  const sampleGrpSorter = getSampleGroupSorter(this);
+  return sampleGrpsArr.sort(sampleGrpSorter);
+}
+function getSampleOrder(data) {
+  const s = this.settings.matrix;
+  this.visibleSampleGrps = /* @__PURE__ */ new Set();
+  const sampleOrder = [];
+  let total = 0, numHiddenGrps = 0;
+  for (const [grpIndex, grp] of this.sampleGroups.entries()) {
+    if (!grp.lst.length) continue;
+    if (grp.isExcluded) numHiddenGrps++;
+    let processedLst = grp.lst;
+    for (const [index, row] of processedLst.entries()) {
+      sampleOrder.push({
+        grp,
+        grpIndex: grpIndex - numHiddenGrps,
+        // : this.sampleGroups.length,
+        row,
+        index,
+        prevGrpTotalIndex: total,
+        totalIndex: total + index,
+        totalHtAdjustments: 0,
+        // may be required when transposed???
+        grpTotals: { htAdjustment: 0 },
+        // may be required when transposed???
+        processedLst
+      });
+    }
+    if (!grp.isExcluded) total += processedLst.length;
+    this.visibleSampleGrps.add(grp);
+  }
+  this.unfilteredSampleOrder = sampleOrder;
+  return sampleOrder.filter((so) => !so.grp.isExcluded);
+}
+function classifyValues(anno, tw, grp, s, sample) {
+  let values = "value" in anno ? [anno.value] : anno.values;
+  if (!values) return { filteredValues: null, countedValues: null, renderedValues: null };
+  if (tw.term.type == "geneVariant" && tw.q?.type == "values" && tw.q.variantFilter) {
+    values = filterVariantValues(values, tw.q.variantFilter);
+  }
+  const isSpecific = [tw.valueFilter || grp.valueFilter].filter((v) => v && true);
+  if (isSpecific.length && isSpecific[0].type !== "tvs" && isSpecific[0].type !== "tvslst")
+    throw `unknown matrix value filter type='${isSpecific.type}'`;
+  let filteredValues = !isSpecific.length ? values : values.filter((v) => sample_match_termvaluesetting(v, isSpecific[0], tw.term, sample));
+  const renderedValues = [];
+  if (tw.term.type == "geneVariant" && tw.q?.type == "values") {
+    filteredValues.sort(this.mclassSorter);
+    if (s.cellEncoding == "") renderedValues.push(...filteredValues);
+    else {
+      const sortedFilteredValues = [];
+      for (const dt of [dtcnv, dtsnvindel, dtfusionrna, dtgeneexpression]) {
+        const v = dt == dtgeneexpression ? filteredValues.find((v2) => v2.dt === dt) : filteredValues.find((v2) => v2.dt === dt && v2.class !== "WT" && v2.class !== "Blank");
+        if (v) renderedValues.push(v);
+        const oneDtV = filteredValues.filter((v2) => v2.dt === dt);
+        sortedFilteredValues.push(...oneDtV);
+      }
+      filteredValues = sortedFilteredValues;
+    }
+  } else {
+    renderedValues.push(...filteredValues);
+  }
+  return {
+    filteredValues,
+    countedValues: filteredValues.filter((v) => {
+      if (tw.term.type == "geneVariant") {
+        if (tw.q?.type == "predefined-groupset" || tw.q?.type == "custom-groupset") {
+          const groupset = tw.q.type == "predefined-groupset" ? tw.term.groupsetting.lst[tw.q.predefined_groupset_idx] : tw.q.customset;
+          if (!groupset) throw "groupset not found";
+          const group = groupset.groups[0];
+          if (v != group.name) return false;
+        } else {
+          if (v.class == "WT" || v.class == "Blank" || s.geneVariantCountSamplesSkipMclass.includes(v.class))
+            return false;
+        }
+      }
+      return true;
+    }),
+    renderedValues
+  };
+}
+function stackSiblingCellsByClass(a, b) {
+  return a.class === b.class ? 0 : a.class === "Blank" ? 1 : b.class == "Blank" ? -1 : a.class < b.class ? -1 : 1;
+}
+
+export {
+  getTermOrder,
+  getSampleGroups,
+  getSampleOrder,
+  classifyValues,
+  stackSiblingCellsByClass,
+  matrix_groups_exports
+};
+//# sourceMappingURL=chunk-GUW7VTUL.js.map

package/dist/chunk-H7F6DMJA.js

@@ -0,0 +1,70 @@
+import {
+  junctionCustomTermSource
+} from "./chunk-MANAUI7R.js";
+import {
+  mayRenderFractionSelection
+} from "./chunk-WD7FZ5EE.js";
+
+// termdb/handlers/junction.ts
+var SearchHandler = class {
+  async init(opts) {
+    if (!opts?.holder) throw new Error("opts.holder is required");
+    if (typeof opts.callback != "function") throw new Error("opts.callback is required");
+    const entries = getJunctionCustomTerms(opts.app.vocabApi.state?.customTerms);
+    render(opts, entries);
+  }
+};
+function getJunctionCustomTerms(customTerms) {
+  if (!Array.isArray(customTerms)) return [];
+  return customTerms.filter((term) => term?.source === junctionCustomTermSource && term.tw?.term);
+}
+function render(opts, entries) {
+  const holder = opts.holder;
+  holder.selectAll("*").remove();
+  const div = holder.append("div").style("padding", "10px 0px");
+  if (!entries.length) {
+    div.append("div").text("Junctions selected from genome browser will be shown here.");
+    return;
+  }
+  const listDiv = div.append("div");
+  const fractionDiv = div.append("div");
+  for (const entry of entries) {
+    if (entry.eventlabel) renderJunctionEvent(listDiv, fractionDiv, entry, opts);
+    else renderJunction(listDiv, entry, opts);
+  }
+  listDiv.append("div").style("font-size", ".7em").style("margin-top", "10px").style("opacity", 0.7).text("Select additional junctions from genome browser.");
+}
+function renderJunction(holder, entry, opts) {
+  const choice = holder.append("div");
+  choice.append("div").attr("class", "ts_pill sja_filter_tag_btn sja_tree_click_term").style("display", "inline-block").style("border-radius", "6px").style("margin", "1px 0").text(entry.tw.term.name).on("click", () => opts.callback(entry.tw.term));
+  addDeleteButton(choice, entry, opts);
+}
+function renderJunctionEvent(holder, fractionDiv, entry, opts) {
+  const eventHolder = holder.append("div");
+  const pillRow = eventHolder.append("div");
+  pillRow.append("div").attr("class", "ts_pill sja_filter_tag_btn sja_tree_click_term").style("display", "inline-block").style("border-radius", "6px").style("margin", "1px 0").text(entry.eventlabel).on("click", () => selectJunctionEvent(holder, fractionDiv, entry, opts));
+  addDeleteButton(pillRow, entry, opts);
+  eventHolder.append("div").style("margin-left", "10px").style("font-size", ".7em").selectAll("div").data(entry.tw.term.termlst, (term) => term.id).enter().append("div").text((term) => term.name);
+}
+function selectJunctionEvent(listDiv, fractionDiv, entry, opts) {
+  const isStaged = mayRenderFractionSelection({
+    term: entry.tw.term,
+    selectionMode: opts.termCollectionSelectionMode,
+    listDiv,
+    fractionDiv,
+    callback: (tw) => opts.callback(tw)
+  });
+  if (!isStaged) opts.callback(entry.tw.term);
+}
+function addDeleteButton(holder, entry, opts) {
+  holder.append("button").attr("data-testid", "sjpp-junction-delete").style("margin-left", "4px").attr("aria-label", `Delete ${entry.name}`).text("\xD7").on("click", async () => {
+    await opts.app.vocabApi.deleteCustomTermById(entry.id);
+    render(opts, getJunctionCustomTerms(opts.app.vocabApi.state?.customTerms));
+  });
+}
+
+export {
+  SearchHandler,
+  getJunctionCustomTerms
+};
+//# sourceMappingURL=chunk-H7F6DMJA.js.map