@sjcrh/proteinpaint-client 2.219.1 → 2.221.0

package/dist/chunk-YUNJBIK4.js

@@ -0,0 +1,243 @@
+import {
+  keyupEnter
+} from "./chunk-WD7FZ5EE.js";
+import {
+  get_bin_label,
+  get_bin_range_equation
+} from "./chunk-4TJO2DGU.js";
+import {
+  toStoredUnit,
+  toUserUnit
+} from "./chunk-W5J3LTYS.js";
+
+// termsetting/handlers/NumCustomBinEditor.ts
+var NumCustomBinEditor = class {
+  constructor(editHandler) {
+    this.dom = {};
+    this.editHandler = editHandler;
+    this.opts = editHandler.opts;
+    this.tw = editHandler.tw;
+    this.termsetting = editHandler.termsetting;
+  }
+  /* bin boundaries are stored in the term's own unit but entered and shown in its user-facing one.
+  both are identity functions unless the term declares valueConversion{} */
+  toDisplay(v) {
+    return toUserUnit(v, this.tw.term);
+  }
+  toStored(v) {
+    return toStoredUnit(v, this.tw.term);
+  }
+  async render(div) {
+    this.tw = this.editHandler.tw;
+    const isRemounting = !!this.dom.inputsDiv && this.editHandler.dom.binsDiv?.node().contains(this.dom.inputsDiv.node());
+    if (!isRemounting) this.q = this.getDefaultQ();
+    await this.editHandler.handler.density.setBinLines(this.getBoundaryOpts());
+    if (isRemounting) return;
+    if (this.dom.inputsDiv) {
+      this.dom.inputsDiv.remove();
+      delete this.dom.inputsDiv;
+    }
+    this.dom.inputsDiv = div.append("div").style("display", "flex").style("width", "100%");
+    this.renderCustomBinInputs();
+  }
+  getBoundaryOpts() {
+    return {
+      values: this.q.lst.slice(1).map((bin) => ({ x: this.toDisplay(bin.startunbounded ? bin.stop : bin.start), isDraggable: true })),
+      // the dragged value arrives in display units, matching what the textarea holds
+      callback: (d, value) => {
+        const boundaryValues = this.q.lst.slice(1).map((d2) => "start" in d2 ? this.toDisplay(d2.start) : "");
+        boundaryValues[d.index] = value;
+        this.dom.customBinBoundaryInput.property("value", boundaryValues.join("\n"));
+        this.handleInputChange("drag");
+        return 0;
+      }
+    };
+  }
+  getDefaultQ() {
+    if (this.tw.q.mode == "discrete" && this.tw.q.type == "custom-bin") {
+      const copy = JSON.parse(JSON.stringify(this.tw.q));
+      copy.lst.forEach((bin) => {
+        if (!bin.label) bin.label = get_bin_label(bin, this.tw.q, this.tw.term.valueConversion);
+        bin.range = get_bin_range_equation(bin, this.tw.q, this.tw.term.valueConversion);
+      });
+      return copy;
+    }
+    const { min, max } = this.editHandler.handler.density_data;
+    const defaultCustomBoundary = (
+      /* when no sample is annotated by this term,
+      minvalue and maxvalue are both null
+      setting defaultCustomBoundary to arbitrary "0" will allow existing UI to work
+      but remains to be evaluated if is really okay to use 0
+      */
+      !Number.isFinite(min) || !Number.isFinite(max) ? 0 : (
+        // minvalue and maxvalue is valid number
+        max != min ? min + (max - min) / 2 : max
+      )
+    );
+    const firstBin = {
+      startunbounded: true,
+      startinclusive: false,
+      stopinclusive: false,
+      stop: +defaultCustomBoundary.toFixed(this.tw.term.type == "integer" ? 0 : 2)
+    };
+    const lastBin = {
+      stopunbounded: true,
+      startinclusive: true,
+      stopinclusive: false,
+      start: +defaultCustomBoundary.toFixed(this.tw.term.type == "integer" ? 0 : 2)
+    };
+    return {
+      mode: "discrete",
+      type: "custom-bin",
+      lst: [
+        // Type '{ label: any; range: any; startunbounded: boolean; startinclusive: boolean; stopinclusive: boolean; stop: number; }' is not assignable to type 'StartUnboundedBin | FullyBoundedBin'.
+        // Property 'start' is missing in type '{ label: any; range: any; startunbounded: boolean; startinclusive: boolean; stopinclusive: boolean; stop: number; }' but required in type 'FullyBoundedBin'.
+        {
+          ...firstBin,
+          label: get_bin_label(firstBin, this.tw.q, this.tw.term.valueConversion),
+          range: get_bin_range_equation(firstBin, this.tw.q, this.tw.term.valueConversion)
+        },
+        {
+          ...lastBin,
+          label: get_bin_label(lastBin, this.tw.q, this.tw.term.valueConversion),
+          range: get_bin_range_equation(lastBin, this.tw.q, this.tw.term.valueConversion)
+        }
+        //satisfies StopUnboundedBin
+      ]
+    };
+  }
+  /******************* Functions for Numerical Custom size bins *******************/
+  renderCustomBinInputs() {
+    const q = this.q;
+    const boundaryDiv = this.dom.inputsDiv.append("div").style("margin-right", "20px");
+    this.dom.rangeAndLabelDiv = this.dom.inputsDiv.append("div");
+    boundaryDiv.append("div").style("margin-bottom", "5px").style("color", "rgb(136, 136, 136)").text("Bin boundaries");
+    this.dom.customBinBoundaryInput = boundaryDiv.append("textarea").style("width", "100px").style("height", "70px").text(
+      q.lst.slice(1).map((d) => "start" in d ? this.toDisplay(d.start) : "").join("\n")
+    ).on("change", () => this.handleInputChange()).on("keyup", async (event) => {
+      if (!keyupEnter(event) && event.key != 8 && event.key != "Enter") return;
+      if (!this.dom.inputsDiv.selectAll("input").node().value) return;
+      this.handleInputChange();
+    });
+    boundaryDiv.append("div").style("font-size", ".6em").style("margin-left", "1px").style("color", "#858585").html("Enter numeric values </br>seperated by ENTER");
+    this.renderBoundaryInputDivs();
+  }
+  renderBoundaryInputDivs() {
+    const data = this.q.lst;
+    const holder = this.dom.rangeAndLabelDiv;
+    holder.selectAll("*").remove();
+    const grid = holder.append("div").style("display", "grid").style("grid-template-columns", "auto auto").style("column-gap", "20px").style("align-items", "center");
+    grid.append("div").style("margin-bottom", "3px").style("color", "rgb(136, 136, 136)").text("Range");
+    grid.append("div").style("margin-bottom", "3px").style("color", "rgb(136, 136, 136)").text("Bin label");
+    for (const d of data) {
+      grid.append("div").attr("name", "range").html(d.range);
+      grid.append("div").append("input").attr("type", "text").style("margin", "2px 0px").property("value", d.label).on("change", function() {
+        d.label = this.value;
+      });
+    }
+    this.dom.customBinRanges = this.dom.inputsDiv.selectAll('div[name="range"]').data(data);
+    this.dom.customBinLabelInput = this.dom.inputsDiv.selectAll("input").data(data);
+  }
+  handleInputChange(eventType = "") {
+    const self = this.tw;
+    const inputs = this.dom.inputsDiv.selectAll("input");
+    inputs.property("value", "");
+    const data = this.processCustomBinInputs();
+    if (data == void 0) {
+      return;
+    }
+    if (self.q.hiddenValues) this.tw.q.hiddenValues = self.q.hiddenValues;
+    if (this.binsChanged(data, this.q.lst)) {
+      this.q.lst = data;
+    }
+    this.renderBoundaryInputDivs();
+    if (eventType != "drag") this.editHandler.handler.density.setBinLines(this.getBoundaryOpts());
+  }
+  binsChanged(data, qlst) {
+    if (data.length != qlst.length) return true;
+    if (Object.keys(data[0]).length !== Object.keys(qlst[0]).length) return true;
+    for (const [i, bin] of qlst.entries()) {
+      for (const k of Object.keys(bin)) {
+        if (bin[k] && bin[k] !== data[i][k]) {
+          return true;
+        }
+      }
+    }
+    return false;
+  }
+  processCustomBinInputs() {
+    const self = this.termsetting;
+    const startinclusive = this.editHandler.boundaryInclusion == "startinclusive";
+    const stopinclusive = this.editHandler.boundaryInclusion == "stopinclusive";
+    const inputs = this.dom.inputsDiv.node().querySelectorAll("input");
+    const inputData = this.dom.customBinBoundaryInput.property("value").split("\n").filter((d) => d != "" && !isNaN(d));
+    const trackBins = new Set(inputData);
+    if (!trackBins.size) return this.tw.q.lst;
+    const sortedBins = Array.from(trackBins).map((v) => this.toStored(Number(v))).sort((a, b) => a - b);
+    const data = [
+      // first bin: StartUnbounded type
+      {
+        startunbounded: true,
+        stop: sortedBins[0],
+        startinclusive: false,
+        stopinclusive,
+        label: inputs[0].value
+      }
+    ];
+    if (!data[0].label) data[0].label = get_bin_label(data[0], self.q, self.term.valueConversion);
+    if (!data[0].range) data[0].range = get_bin_range_equation(data[0], self.q, self.term.valueConversion);
+    for (const [i, d] of sortedBins.entries()) {
+      let bin;
+      const label = inputs[i + 1]?.value || "";
+      if (i !== trackBins.size - 1) {
+        bin = {
+          start: +d,
+          startinclusive,
+          stopinclusive,
+          stop: sortedBins[i + 1],
+          label
+          //range: ''
+        };
+      } else {
+        bin = {
+          start: +d,
+          startinclusive,
+          stopinclusive: false,
+          stopunbounded: true,
+          label
+          //range: ''
+        };
+      }
+      if (bin.label === "" || bin.label === void 0) bin.label = get_bin_label(bin, self.q, self.term.valueConversion);
+      if (bin.range === "" || bin.range === void 0)
+        bin.range = get_bin_range_equation(bin, self.q, self.term.valueConversion);
+      data.push(bin);
+    }
+    return data;
+  }
+  getEditedQ(destroyDom = true) {
+    const lst = this.processCustomBinInputs();
+    if (destroyDom) {
+      for (const name of Object.keys(this.dom)) {
+        this.dom[name].remove();
+        delete this.dom[name];
+      }
+    }
+    return {
+      mode: "discrete",
+      type: "custom-bin",
+      lst
+    };
+  }
+  undoEdits() {
+    this.q = this.getDefaultQ();
+    this.dom.inputsDiv.selectAll("*").remove();
+    this.renderCustomBinInputs();
+    this.editHandler.handler.density.setBinLines(this.getBoundaryOpts());
+  }
+};
+
+export {
+  NumCustomBinEditor
+};
+//# sourceMappingURL=chunk-YUNJBIK4.js.map

package/dist/chunk-Z5ECCUNG.js

@@ -0,0 +1,444 @@
+import {
+  schemeCategory20
+} from "./chunk-V2OJLJSK.js";
+import {
+  isNumericTerm
+} from "./chunk-JHLF2ZC2.js";
+import {
+  category10_default,
+  dtcnv,
+  dtsnvindel
+} from "./chunk-WJLRU5OF.js";
+import {
+  linear,
+  ordinal
+} from "./chunk-4OLM3KSB.js";
+import {
+  __export
+} from "./chunk-HS5PO5ZQ.js";
+
+// plots/matrix/matrix.legend.js
+var matrix_legend_exports = {};
+__export(matrix_legend_exports, {
+  CNVkey2order: () => CNVkey2order,
+  getLegendData: () => getLegendData,
+  getLegendItemText: () => getLegendItemText
+});
+function getLegendData(legendGroups, refs, self) {
+  const s = this.settings.matrix;
+  const legendData = [];
+  const dvt = this.config.divideBy || {};
+  const dvtId = dvt && "id" in dvt ? dvt.id : dvt.name;
+  for (const $id in legendGroups) {
+    const legend = legendGroups[$id];
+    if ($id == "Consequences") {
+      for (const f of this.config.legendValueFilter.lst) {
+        if (f.tvs.term.type !== "geneVariant") continue;
+        if (f.legendGrpName != $id) continue;
+        if (f.tvs.legendFilterType == "geneVariant_soft" && f.filteredOutCats.length == 0) {
+          continue;
+        }
+        for (const v of f.tvs.values) {
+          for (const key of v.mclasslst) {
+            const legendk = v.origin ? v.origin + key : key;
+            legend.values[legendk] = {
+              key,
+              dt: v.dt,
+              origin: v.origin,
+              label: v.label || self.mclass[key].label,
+              fill: v.color || self.mclass[key]?.color,
+              order: CNVkey2order(key),
+              crossedOut: f.tvs.legendFilterType == "geneVariant_hard" ? true : false,
+              greyedOut: f.tvs.legendFilterType == "geneVariant_soft" ? true : false
+            };
+          }
+        }
+      }
+      const keys2 = Object.keys(legend.values);
+      if (!keys2.length) continue;
+      legendData.unshift({
+        name: "Consequences",
+        order: legend.order,
+        $id: legend.$id,
+        dt: legend.dt,
+        origin: legend.origin,
+        items: keys2.map((key, i) => {
+          const item = legend.values[key];
+          const count = item.samples?.size;
+          return {
+            termid: "Consequences",
+            key: item.key,
+            text: this.getLegendItemText(item, count, {}, s),
+            color: item.fill,
+            order: i,
+            border: "1px solid #ccc",
+            count,
+            isLegendItem: true,
+            dt: item.dt,
+            crossedOut: item.crossedOut,
+            greyedOut: item.greyedOut,
+            origin: item.origin
+          };
+        })
+      });
+      legendData[0].items.sort((a, b) => a.text < b.text ? -1 : 1);
+      continue;
+    }
+    const t = $id == dvtId ? { tw: dvt } : this.termOrder.find((t2) => t2.tw.$id == $id || t2.tw.legend?.group == $id) || {
+      tw: { term: { id: $id, name: $id, type: $id === "CNV" ? "geneVariant" : "" } }
+    };
+    for (const f of this.config.legendValueFilter.lst) {
+      const name = t.tw.legend?.group || t.tw.label || t.tw.term.name;
+      if (f.legendGrpName != $id && f.legendGrpName != name && f.tvs.term.name != name) continue;
+      if (f.tvs.term.type == "geneVariant") {
+        for (const v of f.tvs.values) {
+          if (legend.dt && !legend.dt.includes(v.dt)) legend.dt.push(v.dt);
+          if (f.tvs.legendFilterType == "geneVariant_soft" && f.filteredOutCats.length == 0) {
+            continue;
+          }
+          for (const key of v.mclasslst) {
+            const legendk = v.origin ? v.origin + key : key;
+            legend.values[legendk] = {
+              key,
+              dt: v.dt,
+              origin: v.origin,
+              label: v.label || self.mclass[key]?.label || "Gain and loss",
+              fill: v.color || self.mclass[key]?.color,
+              order: CNVkey2order(key),
+              crossedOut: f.tvs.legendFilterType == "geneVariant_hard" ? true : false,
+              greyedOut: f.tvs.legendFilterType == "geneVariant_soft" ? true : false
+            };
+          }
+        }
+      } else {
+        if (isNumericTerm(f.tvs.term)) {
+          if (t.ref?.bins) {
+            for (const v of f.tvs.ranges) {
+              const termValues = t.ref.bins;
+              legend.values[v.name] = {
+                key: v.name,
+                label: termValues?.find((vl) => vl.name == v.name)?.name || v.name,
+                fill: termValues?.find((vl) => vl.name == v.name)?.color,
+                crossedOut: true
+              };
+            }
+          }
+        } else if (f.tvs.term.type == "survival") {
+          for (const v of f.tvs.values) {
+            const termValues = t.tw.term.values;
+            legend.values[v.key] = {
+              key: v.key,
+              label: termValues?.[v.key]?.label || "Exit code: " + v.key,
+              fill: v.key == 1 ? "#ff7f0e" : "#1f77b4",
+              crossedOut: true
+            };
+          }
+        } else {
+          for (const v of f.tvs.values) {
+            const termValues = t.tw.term.values;
+            legend.values[v.key] = {
+              key: v.key,
+              label: termValues?.[v.key]?.label || v.key,
+              fill: termValues?.[v.key]?.color,
+              crossedOut: true
+            };
+          }
+        }
+      }
+    }
+    const keys = Object.keys(legend.values).sort();
+    const hasScale = Object.values(legend.values).find((v) => v.scale);
+    if (hasScale) {
+      if (legend === legendGroups?.CNV) {
+        const gain = legend.values["CNV_amp"];
+        const loss = legend.values["CNV_loss"];
+        if (gain?.scale && loss?.scale) {
+          const colors = loss.scales?.legend.range;
+          const domain = loss.scales?.legend.domain;
+          const setLegendAttr = (item) => {
+            return {
+              $id,
+              domain: item.scales.legend.domain,
+              key: item.key,
+              isLegendItem: true,
+              minLabel: domain[0],
+              //item.minLoss, // item.maxLabel,
+              maxLabel: domain.slice(-1)[0],
+              //item.maxGain, // item.maxLabel,
+              scale: item.scale,
+              termid: "CNV"
+            };
+          };
+          const numericInputs = {
+            cutoffMode: s.cnvValues.cutoffMode,
+            defaultPercentile: s.cnvValues.defaultPercentile,
+            percentile: s.cnvValues.percentile,
+            callback: async (obj) => {
+              const cValues = self.config.settings.matrix.cnvValues;
+              if (obj.cutoffMode == "fixed") {
+                if (cValues.min == null) cValues.min = domain[0];
+                if (cValues.max == null) cValues.max = domain[domain.length - 1];
+                if (obj.min != cValues.min) obj.max = Math.abs(obj.min);
+                else obj.min = -obj.max;
+              }
+              self.config.settings.matrix.cnvValues = {
+                defaultPercentile: self.config.settings.matrix.cnvValues.defaultPercentile,
+                cutoffMode: obj.cutoffMode,
+                min: obj.min,
+                max: obj.max,
+                percentile: obj.percentile
+              };
+              await self.app.dispatch({
+                type: "plot_edit",
+                id: self.opts.id,
+                config: self.config
+              });
+            }
+          };
+          legend.values.CNV_gain_loss = {
+            key: $id,
+            label: "Gain and Loss",
+            dt: dtcnv,
+            order: -1,
+            domain,
+            name: "CNV gain/loss",
+            scale: linear().domain(domain).range(colors),
+            scales: loss.scales,
+            //Prevent the colors and domain recalculating below
+            minLabel: domain[0],
+            //loss.maxLabel,
+            maxLabel: domain.slice(-1)[0],
+            labels: { left: "Loss", right: "Gain" },
+            parents: [Object.assign(setLegendAttr(loss), loss), Object.assign(setLegendAttr(gain), gain)],
+            samples: /* @__PURE__ */ new Set([...gain.samples, ...loss.samples]),
+            numericInputs
+          };
+          delete legend.values[gain.key];
+          delete legend.values[loss.key];
+          keys.splice(keys.indexOf(gain.key), 1);
+          keys.splice(keys.indexOf(loss.key), 1);
+          keys.push("CNV_gain_loss");
+        }
+      }
+      const legendGrpLabelMaxChars = s.legendGrpLabelMaxChars || 26;
+      legendData.push({
+        name: $id.length < legendGrpLabelMaxChars ? $id : $id.slice(0, legendGrpLabelMaxChars) + "...",
+        //name:$id,
+        order: legend.order,
+        $id: legend.$id,
+        dt: legend.dt,
+        origin: legend.origin,
+        hasScale,
+        items: keys.map((key, i) => {
+          const item = legend.values[key];
+          const count = item.samples?.size;
+          if (item.scale) {
+            const colors = item.scales?.legend?.range || getColors(item);
+            const domain = item.scales?.legend?.domain || setColorScaleDomain(item.minLabel, item.maxLabel, item.domain, colors);
+            const opts = {
+              termid: $id,
+              key: item.key,
+              text: this.getLegendItemText(item, count, t, s),
+              width: 100,
+              scale: item.scale,
+              colors,
+              domain,
+              order: "order" in item ? item.order : i,
+              count,
+              isLegendItem: true,
+              dt: item.dt,
+              crossedOut: item.crossedOut,
+              greyedOut: item.greyedOut,
+              origin: item.origin,
+              parents: item.parents,
+              labels: item.labels
+            };
+            if (item.numericInputs) {
+              opts.numericInputs = item.numericInputs;
+            }
+            return opts;
+          } else {
+            return {
+              termid: $id,
+              key: item.key,
+              text: this.getLegendItemText(item, count, t, s),
+              color: item.fill || this.colorScaleByTermId[$id](key),
+              order: "order" in item ? item.order : i,
+              count,
+              isLegendItem: true,
+              dt: item.dt,
+              crossedOut: item.crossedOut,
+              greyedOut: item.greyedOut,
+              origin: item.origin
+            };
+          }
+        })
+      });
+    } else {
+      const grp = $id;
+      const term = t.tw.term;
+      const ref = legend.ref;
+      if (ref.bins)
+        keys.sort((a, b) => ref.bins.findIndex((bin) => bin.name === a) - ref.bins.findIndex((bin) => bin.name === b));
+      else if (ref.keyOrder) keys.sort((a, b) => ref.keyOrder.indexOf(a) - ref.keyOrder.indexOf(b));
+      if (!this.colorScaleByTermId[grp])
+        this.colorScaleByTermId[grp] = keys.length < 11 ? ordinal(category10_default) : ordinal(schemeCategory20);
+      const name = t.tw.legend?.group || t.tw.label || term.name;
+      const legendGrpLabelMaxChars = s.legendGrpLabelMaxChars || 26;
+      legendData.push({
+        name: name.length < legendGrpLabelMaxChars ? name : name.slice(0, legendGrpLabelMaxChars) + "...",
+        order: legend.order,
+        $id: legend.$id,
+        dt: legend.dt,
+        origin: legend.origin,
+        items: keys.map((key, i) => {
+          const item = legend.values[key];
+          const count = item.samples?.size;
+          return {
+            $id,
+            termid: term.id || term.name,
+            key: item.key,
+            text: this.getLegendItemText(item, count, t, s),
+            color: t.scale || item.fill || this.colorScaleByTermId[grp](key),
+            order: "order" in item ? item.order : i,
+            count,
+            isExcluded: item.isExcluded,
+            //onClickCallback: this.handleLegendItemClick,
+            isLegendItem: true,
+            dt: item.dt,
+            crossedOut: item.crossedOut,
+            greyedOut: item.greyedOut,
+            origin: item.origin
+          };
+        })
+      });
+    }
+  }
+  for (const grpFilter of self.config.legendGrpFilter.lst) {
+    if (grpFilter.dt.length == 1 && grpFilter.dt[0] == 4 && !legendData.filter((l) => l.dt)?.find((l) => l.dt.length == 1 && l.dt[0] == 4)) {
+      legendData.push({
+        name: "CNV",
+        dt: grpFilter.dt,
+        origin: grpFilter.origin,
+        crossedOut: true,
+        items: grpFilter.filteredOutCats.map((fc) => {
+          return {
+            dt: 4,
+            termid: "CNV",
+            origin: grpFilter.origin,
+            key: fc,
+            text: self.mclass[fc].label,
+            color: self.mclass[fc]?.color,
+            isLegendItem: true
+          };
+        })
+      });
+    } else if (grpFilter.dt.includes(dtsnvindel)) {
+      const controlLabels = self.settings.matrix.controlLabels;
+      const groupName = grpFilter.origin ? `${grpFilter.origin[0].toUpperCase() + grpFilter.origin.slice(1)} ${controlLabels.Mutations}` : controlLabels.Mutations;
+      if (!legendData.filter((l) => l.dt)?.find((l) => l.dt.includes(dtsnvindel) && l.origin == grpFilter.origin)) {
+        legendData.push({
+          name: groupName,
+          dt: grpFilter.dt,
+          origin: grpFilter.origin,
+          crossedOut: true,
+          items: grpFilter.filteredOutCats.map((fc) => {
+            return {
+              dt: self.mclass[fc].dt,
+              origin: grpFilter.origin,
+              termid: groupName,
+              key: fc,
+              text: self.mclass[fc].label,
+              color: self.mclass[fc]?.color,
+              isLegendItem: true
+            };
+          })
+        });
+      }
+    } else if (grpFilter.dt.length == 1 && grpFilter.dt[0] == 2 && !legendData.filter((l) => l.dt)?.find((l) => l.dt.length == 1 && l.dt[0] == 2)) {
+      legendData.push({
+        name: "Fusion RNA",
+        dt: grpFilter.dt,
+        origin: grpFilter.origin,
+        crossedOut: true,
+        items: grpFilter.filteredOutCats.map((fc) => {
+          return {
+            dt: 2,
+            origin: grpFilter.origin,
+            termid: "Fusion RNA",
+            key: fc,
+            text: self.mclass[fc].label,
+            color: self.mclass[fc]?.color,
+            isLegendItem: true
+          };
+        })
+      });
+    } else if (grpFilter.dt.length == 1 && grpFilter.dt[0] == 5 && !legendData.filter((l) => l.dt)?.find((l) => l.dt.length == 1 && l.dt[0] == 5)) {
+      legendData.push({
+        name: "Structural Variation",
+        dt: grpFilter.dt,
+        origin: grpFilter.origin,
+        crossedOut: true,
+        items: grpFilter.filteredOutCats.map((fc) => {
+          return {
+            dt: 5,
+            origin: grpFilter.origin,
+            termid: "Structural Variation",
+            key: fc,
+            text: self.mclass[fc].label,
+            color: self.mclass[fc]?.color,
+            isLegendItem: true
+          };
+        })
+      });
+    }
+  }
+  for (const itemsGrp of legendData) {
+    itemsGrp.items.sort((a, b) => {
+      const getStatusOrder = (item) => {
+        if (!item.greyedOut && !item.crossedOut) return 0;
+        if (item.greyedOut && !item.crossedOut) return 1;
+        if (item.crossedOut) return 2;
+        return 3;
+      };
+      return getStatusOrder(a) - getStatusOrder(b);
+    });
+  }
+  return legendData.sort(
+    (a, b) => a.crossedOut && b.crossedOut ? 0 : a.crossedOut ? 1 : b.crossedOut ? -1 : a.order && b.order ? a.order - b.order : a.order ? -1 : b.order ? 1 : 0
+  );
+}
+function getLegendItemText(item, count, t, s) {
+  if (item.crossedOut || item.greyedOut) {
+    return item.label;
+  }
+  let text = item.label;
+  const notes = [count];
+  if (item.isExcluded) notes.push("hidden");
+  if (t?.tw?.term?.type == "geneVariant" && s.geneVariantCountSamplesSkipMclass.includes(item.key))
+    notes.push("not counted");
+  if (!notes.length) return text;
+  return text += ` (${notes.join(", ")})`;
+}
+function setColorScaleDomain(min, max, domain, colors) {
+  if (domain[0] === min && domain[domain.length - 1] === max) return domain;
+  const step = (max - min) / (colors.length - 1);
+  return colors.map((_, i) => {
+    if (i === (colors.length - 1) / 2 && min < 0 && max > 0) return 0;
+    return min + step * i;
+  });
+}
+function getColors(item) {
+  return item.domain?.map((c) => item.scale(c)) || item.scale.range();
+}
+function CNVkey2order(key) {
+  return key == "CNV_homozygous_deletion" ? -5 : key == "CNV_amplification" ? -4 : key == "CNV_loss" ? -3 : key == "CNV_amp" ? -2 : key == "CNV_loh" ? -1 : 0;
+}
+
+export {
+  getLegendData,
+  getLegendItemText,
+  CNVkey2order,
+  matrix_legend_exports
+};
+//# sourceMappingURL=chunk-Z5ECCUNG.js.map