@sjcrh/proteinpaint-client 2.219.1 → 2.220.0
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/dist/2dmaf-KRIX5DBS.js +1362 -0
- package/dist/AggMatrixInput-GBQD74NV.js +402 -0
- package/dist/AggregateMatrix-U2MOQOSZ.js +37 -0
- package/dist/AppHeader-OBZWUCOD.js +826 -0
- package/dist/BoxPlot-ZK6Q5JGE.js +1229 -0
- package/dist/CorrelationVolcano-WGR4JIGK.js +613 -0
- package/dist/Cuminc-I6D6YSIL.js +1217 -0
- package/dist/DE-HO7UBKPC.js +85 -0
- package/dist/DEinput-6LX4I65N.js +479 -0
- package/dist/DM-WYKLX4IC.js +86 -0
- package/dist/DifferentialAnalysis-L5VVBCVZ.js +236 -0
- package/dist/Disco-HLARIYXU.js +3384 -0
- package/dist/Disco.UI-W64WFVC3.js +239 -0
- package/dist/DmrPlot-BKQOT4JM.js +361 -0
- package/dist/GB-WKFGDJYW.js +1388 -0
- package/dist/GSEA-DCCJI5JE.js +870 -0
- package/dist/GeneExpInput-APLFNE6N.js +38 -0
- package/dist/Geomap-FTKWCV4J.js +80 -0
- package/dist/HicApp-ZGZKO4Y4.js +2240 -0
- package/dist/IDCViewer-MXB3OZUZ.js +10808 -0
- package/dist/NumBinaryEditor-S3MHUVZ5.js +274 -0
- package/dist/NumBinaryEditor.unit.spec-264X5ULG.js +308 -0
- package/dist/NumContEditor-MKEZCZMR.js +100 -0
- package/dist/NumContEditor.unit.spec-KBRAIU7M.js +160 -0
- package/dist/NumCustomBinEditor-OSF64BFC.js +29 -0
- package/dist/NumCustomBinEditor.unit.spec-T2SRBXTV.js +393 -0
- package/dist/NumDiscreteEditor-PVW5HRRQ.js +165 -0
- package/dist/NumDiscreteEditor.unit.spec-GUK7VWMR.js +229 -0
- package/dist/NumRegularBinEditor-757VRGFQ.js +29 -0
- package/dist/NumRegularBinEditor.unit.spec-JUIGEH3Z.js +274 -0
- package/dist/NumSplineEditor-U6MVFSCZ.js +205 -0
- package/dist/NumSplineEditor.unit.spec-PSH6YENX.js +220 -0
- package/dist/NumericDensity-YIP25Z4Y.js +29 -0
- package/dist/NumericDensity.unit.spec-3OSIZJHH.js +414 -0
- package/dist/NumericHandler-D2CO3FTS.js +30 -0
- package/dist/NumericHandler.unit.spec-RNFVGO2I.js +225 -0
- package/dist/ProteomeInput-ZOBJ2VU6.js +610 -0
- package/dist/Regression-ABKJOOMQ.js +1412 -0
- package/dist/RunChart2-D5CEEFEE.js +744 -0
- package/dist/SC-RLVEECU5.js +1290 -0
- package/dist/Violin-PCNX2CWV.js +1092 -0
- package/dist/Volcano-NVFNO7NE.js +2661 -0
- package/dist/Volcano-NVFNO7NE.js.map +7 -0
- package/dist/Wsi-MAMCK5YZ.js +636 -0
- package/dist/aboutSunburst-VSQADTFD.js +86 -0
- package/dist/aboutSunburst-VSQADTFD.js.map +7 -0
- package/dist/adSandbox-5YFAQZO6.js +29 -0
- package/dist/animatedBubbleChart-GM2GXDP3.js +542 -0
- package/dist/app-FNNCH37H.js +28 -0
- package/dist/app-ID5S5FUP.js +38 -0
- package/dist/app.js +14 -14
- package/dist/bam-JZLYXHMF.js +872 -0
- package/dist/barchart-EAXXILCH.js +38 -0
- package/dist/barchart2-E6A4UMUB.js +305 -0
- package/dist/block-VMVJH77F.js +6203 -0
- package/dist/block-VMVJH77F.js.map +7 -0
- package/dist/block.init-TUCGKLXG.js +29 -0
- package/dist/block.mds.expressionrank-YVROHZVX.js +350 -0
- package/dist/block.mds.geneboxplot-TQNEWBJY.js +819 -0
- package/dist/block.mds.junction-ZOSTZQF5.js +1534 -0
- package/dist/block.mds.svcnv-XSTSJ4ZD.js +6413 -0
- package/dist/block.svg-D6HXL4SC.js +155 -0
- package/dist/block.tk.aicheck-7RNC4HRR.js +274 -0
- package/dist/block.tk.bam-L3U5YH3F.js +1897 -0
- package/dist/block.tk.bigwig.ui-UVSZ7LWQ.js +202 -0
- package/dist/block.tk.hicstraw-YFBJR5LO.js +814 -0
- package/dist/block.tk.junction-DNRK2JNQ.js +2353 -0
- package/dist/block.tk.junction.textmatrixui-EN4ADCAU.js +190 -0
- package/dist/block.tk.ld-I5CTAJ4K.js +90 -0
- package/dist/block.tk.menu-HUZBY7OM.js +1050 -0
- package/dist/block.tk.pgv-KA6BFYPY.js +934 -0
- package/dist/brainImaging-OQB2ZHCU.js +550 -0
- package/dist/brainRegions-2CRVMS24.js +213 -0
- package/dist/bubbleHeatmap-MANNFEG2.js +374 -0
- package/dist/cellTypeBubbleHeatmap-LRK4R4EC.js +274 -0
- package/dist/chunk-2NB5HVXB.js +159 -0
- package/dist/chunk-2OMX5AYB.js +195 -0
- package/dist/chunk-3E26ITYK.js +55 -0
- package/dist/chunk-3H4FCRAN.js +266 -0
- package/dist/chunk-4GKC43U3.js +480 -0
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- package/dist/chunk-4TJO2DGU.js +2297 -0
- package/dist/chunk-4TJO2DGU.js.map +7 -0
- package/dist/chunk-4ZV6SE4B.js +240 -0
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- package/dist/chunk-KCVBFXGO.js +2941 -0
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- package/dist/chunk-M6OSJMVD.js +536 -0
- package/dist/chunk-M6OSJMVD.js.map +7 -0
- package/dist/chunk-MANAUI7R.js +54 -0
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- package/dist/chunk-XYUERIZ6.js +4389 -0
- package/dist/chunk-XYUERIZ6.js.map +7 -0
- package/dist/chunk-YDIIKD7O.js +102 -0
- package/dist/chunk-YLGSRK75.js +102 -0
- package/dist/chunk-YR6EXI2K.js +184 -0
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- package/dist/chunk-Z5ECCUNG.js +444 -0
- package/dist/chunk-Z7Q2O5Y7.js +237 -0
- package/dist/cohort-ERDL7EJU.js +66 -0
- package/dist/cohortSunburst-KSTVS3OQ.js +402 -0
- package/dist/condition-CTJYHRJG.js +323 -0
- package/dist/controls-MMMRBTZL.js +30 -0
- package/dist/controls.config-ZKMQI27Q.js +30 -0
- package/dist/correlation-NEQNBQTT.js +91 -0
- package/dist/customdata.inputui-THUR7DF5.js +280 -0
- package/dist/dataDownload-ZMAJUKBX.js +326 -0
- package/dist/dataDownload-ZMAJUKBX.js.map +7 -0
- package/dist/databrowser.ui-A6ZSIUG4.js +421 -0
- package/dist/dictionary-TQUVCHIN.js +109 -0
- package/dist/dnaMethylation-ZMJYY3ML.js +29 -0
- package/dist/dnaMethylation.integration.spec-5DTBGTYB.js +194 -0
- package/dist/dofetch-KBTN6OW4.js +49 -0
- package/dist/e2pca-DNWBF545.js +340 -0
- package/dist/ep-JNH3HMY4.js +1247 -0
- package/dist/expclust.gdc.spec-2NJ7JVJW.js +298 -0
- package/dist/facet-RWQFAVVU.js +556 -0
- package/dist/gb-OT2Z3Y7J.js +77 -0
- package/dist/geneExpClustering-TPYGSTMO.js +240 -0
- package/dist/geneExpression-4K3OTXBZ.js +29 -0
- package/dist/geneExpression-KPUOZ4PT.js +309 -0
- package/dist/geneExpression.unit.spec-26MCGRAP.js +151 -0
- package/dist/geneORA-GNXKCN45.js +269 -0
- package/dist/geneRanking-LV6W6TT7.js +544 -0
- package/dist/geneVariant-B2SYTHG6.js +289 -0
- package/dist/geneVariant-O4XG5VEM.js +32 -0
- package/dist/geneVariant.integration.spec-YYVPAFXT.js +672 -0
- package/dist/genefusion.ui-CVGGYVV3.js +299 -0
- package/dist/geneset-MBMCJNXT.js +199 -0
- package/dist/genomeBrowser.spec-OVXFKEIU.js +272 -0
- package/dist/grin2-OXRU465E.js +945 -0
- package/dist/grin2-YCJGBRFG.js +66 -0
- package/dist/hierCluster-KNPWL5KD.js +51 -0
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- package/dist/importPlot-3SSCNROC.js +8 -0
- package/dist/isoformExpression-BTMJNAAO.js +31 -0
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package/dist/chunk-NS2MZN3C.js
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function getSampleSorter(self, settings, rows, opts = {}) {
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validateSettings(s);
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function getSortSamplesByValues(st, self, rows, s) {
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return a[$id]?.numerators_sum - b[$id]?.numerators_sum;
|
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145
|
-
}
|
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146
|
-
if ($id in a) return -1;
|
|
147
|
-
if ($id in b) return 1;
|
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148
|
-
return 0;
|
|
149
|
-
};
|
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150
|
-
}
|
|
151
|
-
if (t.tw.q?.mode == "continuous") {
|
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152
|
-
return (a, b) => {
|
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153
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-
if ($id in a && $id in b) {
|
|
154
|
-
return a[$id]?.value - b[$id]?.value;
|
|
155
|
-
}
|
|
156
|
-
if ($id in a) return -1;
|
|
157
|
-
if ($id in b) return 1;
|
|
158
|
-
return 0;
|
|
159
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-
};
|
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160
|
-
}
|
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161
|
-
const values = [];
|
|
162
|
-
if (t?.term?.values) {
|
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163
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-
for (const v of term.values) {
|
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164
|
-
values.push(v.key);
|
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165
|
-
}
|
|
166
|
-
values.sort((a, b) => term.values[a].order < term.values[a].order ? -1 : 1);
|
|
167
|
-
} else if (t?.ref?.bins) {
|
|
168
|
-
values.push(...t.ref.bins.map((b) => b.name));
|
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169
|
-
} else if (t.tw.q?.type == "predefined-groupset" || t.tw.q?.type == "custom-groupset") {
|
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170
|
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const groupset = t.tw.q.type == "predefined-groupset" ? t.tw.term.groupsetting.lst[t.tw.q.predefined_groupset_idx] : t.tw.q.customset;
|
|
171
|
-
if (!groupset) throw "groupset missing";
|
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172
|
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const grpNames = groupset.groups.filter((group) => !group.uncomputable).map((group) => group.name);
|
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173
|
-
values.push(...grpNames);
|
|
174
|
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} else {
|
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175
|
-
for (const row of rows) {
|
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176
|
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if (!($id in row)) continue;
|
|
177
|
-
const v = row[$id].override?.key || row[$id].key;
|
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178
|
-
if (values.indexOf(v) == -1) values.push(v);
|
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179
|
-
}
|
|
180
|
-
}
|
|
181
|
-
return (a, b) => {
|
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182
|
-
if (!a[$id] && !b[$id]) return 0;
|
|
183
|
-
if (!a[$id]) return b[$id].override ? -1 : 1;
|
|
184
|
-
if (!b[$id]) return a[$id].override ? 1 : -1;
|
|
185
|
-
if (a[$id].override && b[$id].override) {
|
|
186
|
-
const ak = "order" in a[$id].override ? a[$id].override.order : values.indexOf(a[$id].override.key);
|
|
187
|
-
const bk = "order" in b[$id].override ? b[$id].override.order : values.indexOf(b[$id].override.key);
|
|
188
|
-
return ak - bk;
|
|
189
|
-
}
|
|
190
|
-
if (!a[$id].override && !b[$id].override) {
|
|
191
|
-
return values.indexOf(a[$id].key) - values.indexOf(b[$id].key);
|
|
192
|
-
}
|
|
193
|
-
if (!a[$id].override) return -1;
|
|
194
|
-
if (!b[$id].override) return 1;
|
|
195
|
-
return 0;
|
|
196
|
-
};
|
|
197
|
-
}
|
|
198
|
-
function getSortSamplesByDt(st, self, rows, s) {
|
|
199
|
-
const { $id, sortSamples, term: term2 } = st;
|
|
200
|
-
const order = sortSamples.order;
|
|
201
|
-
const nextRound = order.length + 1;
|
|
202
|
-
const dt = /* @__PURE__ */ new Map();
|
|
203
|
-
function setSortIndex(row) {
|
|
204
|
-
if (!($id in row)) {
|
|
205
|
-
dt.set(row.sample, nextRound);
|
|
206
|
-
return;
|
|
207
|
-
}
|
|
208
|
-
const values = row[$id].filteredValues || row[$id].values;
|
|
209
|
-
if (sortSamples.filter && !findMatchingValue(values, sortSamples.filter.values)) {
|
|
210
|
-
dt.set(row.sample, nextRound);
|
|
211
|
-
return;
|
|
212
|
-
}
|
|
213
|
-
const indices = values.map((v) => order.indexOf(v.dt)).filter((i) => i !== -1);
|
|
214
|
-
dt.set(row.sample, indices.length ? Math.min(...indices) : nextRound);
|
|
215
|
-
}
|
|
216
|
-
return (a, b) => {
|
|
217
|
-
if (!dt.has(a.sample)) setSortIndex(a);
|
|
218
|
-
if (!dt.has(b.sample)) setSortIndex(b);
|
|
219
|
-
return dt.get(a.sample) - dt.get(b.sample);
|
|
220
|
-
};
|
|
221
|
-
}
|
|
222
|
-
function getSortSamplesByClass(st, self, rows, s) {
|
|
223
|
-
const { $id, sortSamples } = st;
|
|
224
|
-
if (sortSamples.disabled) return () => 0;
|
|
225
|
-
const m = self.config.settings.matrix;
|
|
226
|
-
const includeSSM = m.showMatrixMutation != "none" && !m.allMatrixMutationHidden;
|
|
227
|
-
const includeCNV = m.showMatrixCNV != "none" && !m.allMatrixCNVHidden;
|
|
228
|
-
const order = sortSamples.order.filter(
|
|
229
|
-
includeSSM && includeCNV ? (v) => !m.hiddenVariants.includes(v) : !includeSSM && !includeCNV ? () => false : includeSSM ? (v) => m.mutationClasses.includes(v) && !m.hiddenVariants.includes(v) : includeCNV ? (v) => v.startsWith("CNV_") && !m.hiddenVariants.includes(v) : (v) => !v.startsWith("CNV_")
|
|
230
|
-
);
|
|
231
|
-
if (!order.length && sortSamples.ignoreEmptyFilteredOrder) return () => 0;
|
|
232
|
-
const nextRound = "z";
|
|
233
|
-
const cls = /* @__PURE__ */ new Map();
|
|
234
|
-
function setSortIndex(row) {
|
|
235
|
-
if (!($id in row)) {
|
|
236
|
-
cls.set(row.sample, nextRound);
|
|
237
|
-
return;
|
|
238
|
-
}
|
|
239
|
-
const values = row[$id].renderedValues || row[$id].filteredValues || row[$id].values;
|
|
240
|
-
if (sortSamples.filter && !findMatchingValue(values, sortSamples.filter.values)) {
|
|
241
|
-
cls.set(row.sample, nextRound);
|
|
242
|
-
return;
|
|
243
|
-
}
|
|
244
|
-
const vals = values.map((v) => v.class);
|
|
245
|
-
if (!order.find((mcls) => vals.includes(mcls))) {
|
|
246
|
-
cls.set(row.sample, nextRound);
|
|
247
|
-
return;
|
|
248
|
-
} else if (!sortSamples.isOrdered) {
|
|
249
|
-
cls.set(row.sample, "1");
|
|
250
|
-
} else {
|
|
251
|
-
const str = order.map((mcls) => vals.includes(mcls) ? "1" : "x");
|
|
252
|
-
cls.set(row.sample, str);
|
|
253
|
-
}
|
|
254
|
-
}
|
|
255
|
-
return (a, b) => {
|
|
256
|
-
if (!cls.has(a.sample)) setSortIndex(a);
|
|
257
|
-
if (!cls.has(b.sample)) setSortIndex(b);
|
|
258
|
-
const ca = cls.get(a.sample);
|
|
259
|
-
const cb = cls.get(b.sample);
|
|
260
|
-
return ca < cb ? -1 : ca > cb ? 1 : 0;
|
|
261
|
-
};
|
|
262
|
-
}
|
|
263
|
-
function findMatchingValue(annoValues, filterValues) {
|
|
264
|
-
for (const v of annoValues) {
|
|
265
|
-
for (const f of filterValues) {
|
|
266
|
-
if ((!f.dt || v.dt === f.dt) && (!f.mclassLst || f.mclassLst.includes(v.class)) && (!f.class || f.class === v.class) && (!f.origin || v.origin === f.origin)) {
|
|
267
|
-
return true;
|
|
268
|
-
}
|
|
269
|
-
}
|
|
270
|
-
}
|
|
271
|
-
}
|
|
272
|
-
function getTermSorter(self, s, grp) {
|
|
273
|
-
if (grp?.type == "hierCluster") return self.hcTermSorter;
|
|
274
|
-
if (s.sortTermsBy == "asListed") {
|
|
275
|
-
return (a, b) => a.index - b.index;
|
|
276
|
-
}
|
|
277
|
-
if (s.sortTermsBy != "sampleCount") {
|
|
278
|
-
throw `unsupported s.sortTermsBy='${s.sortTermsBy}'`;
|
|
279
|
-
}
|
|
280
|
-
return (a, b) => {
|
|
281
|
-
if (self.app.vocabApi.termdbConfig?.matrix?.sortDictTermsFirst) {
|
|
282
|
-
if (a.tw?.term?.id && !b.tw?.term?.id) return -1;
|
|
283
|
-
if (!a.tw?.term?.id && b.tw?.term?.id) return 1;
|
|
284
|
-
}
|
|
285
|
-
if (b.counts.samples !== a.counts.samples) return b.counts.samples - a.counts.samples;
|
|
286
|
-
if (b.counts.hits !== a.counts.hits) return b.counts.hits - a.counts.hits;
|
|
287
|
-
return a.index - b.index;
|
|
288
|
-
};
|
|
289
|
-
}
|
|
290
|
-
function getSortOptions(termdbConfig, controlLabels = {}, matrixSettings) {
|
|
291
|
-
const s = matrixSettings || termdbConfig?.matrix?.settings || {};
|
|
292
|
-
const l = Object.assign({ sample: "sample" }, controlLabels, s.controlLabels || {});
|
|
293
|
-
const sortOptions = {};
|
|
294
|
-
if (s.sortPriority) {
|
|
295
|
-
const order = 1;
|
|
296
|
-
Object.values(sortOptions).forEach((d) => {
|
|
297
|
-
if (d.order >= order) d.order += 1;
|
|
298
|
-
});
|
|
299
|
-
sortOptions.custom = {
|
|
300
|
-
label: s.sortPriority.label || "Custom sort",
|
|
301
|
-
value: "custom",
|
|
302
|
-
order,
|
|
303
|
-
sortPriority: s.sortPriority
|
|
304
|
-
};
|
|
305
|
-
}
|
|
306
|
-
const cnvClasses = [mclasscnvAmp, mclasscnvHomozygousDel, mclasscnvgain, mclasscnvloss, mclasscnvloh];
|
|
307
|
-
const proteinChangingClasses = (s.proteinChangingMutations || []).filter(
|
|
308
|
-
(mcls) => !s.truncatingMutations.includes(mcls)
|
|
309
|
-
);
|
|
310
|
-
const sortedClasses = ["Fuserna", ...s.truncatingMutations || [], ...cnvClasses, ...proteinChangingClasses];
|
|
311
|
-
sortOptions.a = s.sortOptions?.a ? reshapeSortPriority(s.sortOptions.a, l) : {
|
|
312
|
-
//label: l.Mutation + ' categories', //'CNV+SSM > SSM-only > CNV-only',
|
|
313
|
-
// altLabels: {
|
|
314
|
-
// mutationOnly: 'SSM',
|
|
315
|
-
// cnvOnly: 'CNV',
|
|
316
|
-
// },
|
|
317
|
-
value: "a",
|
|
318
|
-
order: 1,
|
|
319
|
-
// this is used for list order as a sorter option in a dropdown
|
|
320
|
-
sortPriority: [
|
|
321
|
-
{
|
|
322
|
-
label: `For each gene mutation, sort ${l.samples} by matching data`,
|
|
323
|
-
types: ["geneVariant"],
|
|
324
|
-
tiebreakers: [
|
|
325
|
-
{
|
|
326
|
-
skip: !s.mutationClasses.includes("Fuserna"),
|
|
327
|
-
// not visible, cannot be enabled
|
|
328
|
-
label: `${l.Samples} with Fusion RNASeq > without`,
|
|
329
|
-
filter: {
|
|
330
|
-
values: [
|
|
331
|
-
{
|
|
332
|
-
dt: dtfusionrna
|
|
333
|
-
}
|
|
334
|
-
]
|
|
335
|
-
},
|
|
336
|
-
by: "class",
|
|
337
|
-
isOrdered: false,
|
|
338
|
-
order: [
|
|
339
|
-
"Fuserna"
|
|
340
|
-
/*'WT', 'Blank'*/
|
|
341
|
-
]
|
|
342
|
-
},
|
|
343
|
-
{
|
|
344
|
-
label: `${l.Samples} with truncating mutations > without`,
|
|
345
|
-
filter: {
|
|
346
|
-
values: [
|
|
347
|
-
{
|
|
348
|
-
dt: dtsnvindel
|
|
349
|
-
}
|
|
350
|
-
]
|
|
351
|
-
},
|
|
352
|
-
by: "class",
|
|
353
|
-
isOrdered: false,
|
|
354
|
-
order: [
|
|
355
|
-
...s.truncatingMutations
|
|
356
|
-
// // truncating
|
|
357
|
-
// 'F', // FRAMESHIFT
|
|
358
|
-
// 'N', // NONSENSE
|
|
359
|
-
// 'L', // SPLICE
|
|
360
|
-
// 'P', // SPLICE_REGION
|
|
361
|
-
// // indel
|
|
362
|
-
// 'D', // PROTEINDEL
|
|
363
|
-
// 'I', // PROTEININS
|
|
364
|
-
// 'ProteinAltering',
|
|
365
|
-
// // point
|
|
366
|
-
// 'M' // MISSENSE
|
|
367
|
-
],
|
|
368
|
-
// do not have the option to add unused protein-changing mutations,
|
|
369
|
-
// because the "truncating" label for this tiebreaker will not make sense
|
|
370
|
-
notUsed: []
|
|
371
|
-
},
|
|
372
|
-
{
|
|
373
|
-
label: `${l.Samples} with CNV data > without`,
|
|
374
|
-
mayToggle: true,
|
|
375
|
-
filter: {
|
|
376
|
-
values: [
|
|
377
|
-
{
|
|
378
|
-
dt: dtcnv
|
|
379
|
-
}
|
|
380
|
-
]
|
|
381
|
-
},
|
|
382
|
-
by: "class",
|
|
383
|
-
isOrdered: true,
|
|
384
|
-
disabled: true,
|
|
385
|
-
// visible, can be enabled
|
|
386
|
-
order: cnvClasses
|
|
387
|
-
},
|
|
388
|
-
{
|
|
389
|
-
disabled: false,
|
|
390
|
-
mayToggle: true,
|
|
391
|
-
label: `${l.Samples} with protein-changing mutations > without`,
|
|
392
|
-
filter: {
|
|
393
|
-
values: [
|
|
394
|
-
{
|
|
395
|
-
dt: dtsnvindel
|
|
396
|
-
}
|
|
397
|
-
]
|
|
398
|
-
},
|
|
399
|
-
by: "class",
|
|
400
|
-
isOrdered: false,
|
|
401
|
-
// by default, do not include truncating mutations here since they may
|
|
402
|
-
// already be used in the tiebreaker with truncating mutations
|
|
403
|
-
order: proteinChangingClasses,
|
|
404
|
-
notUsed: s.truncatingMutations
|
|
405
|
-
},
|
|
406
|
-
{
|
|
407
|
-
disabled: false,
|
|
408
|
-
mayToggle: true,
|
|
409
|
-
label: `${l.Samples} with other classification > without`,
|
|
410
|
-
filter: {
|
|
411
|
-
values: [
|
|
412
|
-
{
|
|
413
|
-
dt: dtsnvindel
|
|
414
|
-
}
|
|
415
|
-
]
|
|
416
|
-
},
|
|
417
|
-
by: "class",
|
|
418
|
-
isOrdered: false,
|
|
419
|
-
order: s.mutationClasses.filter((cls) => !sortedClasses.includes(cls) && cls != "Blank"),
|
|
420
|
-
notUsed: []
|
|
421
|
-
}
|
|
422
|
-
]
|
|
423
|
-
},
|
|
424
|
-
{
|
|
425
|
-
label: `For each dictionary variable, sort ${l.samples} by matching data`,
|
|
426
|
-
types: ["categorical", "integer", "float", "survival"],
|
|
427
|
-
tiebreakers: [
|
|
428
|
-
{
|
|
429
|
-
label: "Values",
|
|
430
|
-
by: "values"
|
|
431
|
-
}
|
|
432
|
-
]
|
|
433
|
-
}
|
|
434
|
-
]
|
|
435
|
-
};
|
|
436
|
-
sortOptions.name = {
|
|
437
|
-
label: `By ${l.sample} name, ID, or label`,
|
|
438
|
-
value: "name",
|
|
439
|
-
order: Object.values(sortOptions).length
|
|
440
|
-
};
|
|
441
|
-
return sortOptions;
|
|
442
|
-
}
|
|
443
|
-
function getSampleGroupSorter(self) {
|
|
444
|
-
const s = self.settings.matrix;
|
|
445
|
-
if (s.sortSampleGrpsBy == "hits")
|
|
446
|
-
return (a, b) => {
|
|
447
|
-
if (a.lst.length && !b.lst.length) return -1;
|
|
448
|
-
if (!a.lst.length && b.lst.length) return 1;
|
|
449
|
-
return b.totalCountedValues - a.totalCountedValues;
|
|
450
|
-
};
|
|
451
|
-
if (s.sortSampleGrpsBy == "sampleCount")
|
|
452
|
-
return (a, b) => {
|
|
453
|
-
if (a.lst.length && !b.lst.length) return -1;
|
|
454
|
-
if (!a.lst.length && b.lst.length) return 1;
|
|
455
|
-
if (a.lst.length == b.lst.length) {
|
|
456
|
-
return defaultSorter(a, b);
|
|
457
|
-
}
|
|
458
|
-
return b.lst.length - a.lst.length;
|
|
459
|
-
};
|
|
460
|
-
if (!self.config.divideBy?.$id) return defaultSorter;
|
|
461
|
-
const ref = self.data.refs.byTermId[self.config.divideBy.$id];
|
|
462
|
-
if (ref && !ref.keyOrder) ref.keyOrder = ref.bins ? ref.bins.map((b) => b.name) : [];
|
|
463
|
-
const predefinedKeyOrder = self.data.refs.byTermId[self.config.divideBy.$id]?.keyOrder;
|
|
464
|
-
if (!predefinedKeyOrder) return defaultSorter;
|
|
465
|
-
return (a, b) => {
|
|
466
|
-
a.order = predefinedKeyOrder.indexOf(a.id);
|
|
467
|
-
if (a.order == -1) delete a.order;
|
|
468
|
-
b.order = predefinedKeyOrder.indexOf(b.id);
|
|
469
|
-
if (b.order == -1) delete b.order;
|
|
470
|
-
if ("order" in a && "order" in b) return a.order - b.order;
|
|
471
|
-
if ("order" in a) return -1;
|
|
472
|
-
if ("order" in b) return 1;
|
|
473
|
-
if (a.tw?.term?.values?.[a.id]?.order && b.tw?.term?.values?.[b.id]?.order) {
|
|
474
|
-
return a.tw.term.values[a.id].order - b.tw.term.values[b.id].order;
|
|
475
|
-
}
|
|
476
|
-
return defaultSorter(a, b);
|
|
477
|
-
};
|
|
478
|
-
}
|
|
479
|
-
function defaultSorter(a, b) {
|
|
480
|
-
return a.name < b.name ? -1 : 1;
|
|
481
|
-
}
|
|
482
|
-
function getMclassSorter(self) {
|
|
483
|
-
const s = self.settings.matrix;
|
|
484
|
-
const activeOption = s.sortOptions[s.sortSamplesBy].sortPriority ? s.sortOptions[s.sortSamplesBy] : s.sortOptions.a;
|
|
485
|
-
const mclassPriority = [];
|
|
486
|
-
activeOption.sortPriority.forEach((obj) => {
|
|
487
|
-
if (obj.types.includes("geneVariant")) {
|
|
488
|
-
obj.tiebreakers.forEach((tiebreaker) => {
|
|
489
|
-
if (tiebreaker.by == "class" && tiebreaker.order) {
|
|
490
|
-
mclassPriority.push(...tiebreaker.order.filter((t) => t !== "WT" && t !== "Blank"));
|
|
491
|
-
}
|
|
492
|
-
});
|
|
493
|
-
}
|
|
494
|
-
});
|
|
495
|
-
const sorter = (a, b) => {
|
|
496
|
-
const ai = mclassPriority.indexOf(a.class);
|
|
497
|
-
const bi = mclassPriority.indexOf(b.class);
|
|
498
|
-
return ai == -1 && bi == -1 ? 0 : mclassPriority.indexOf(a.class) == -1 ? 1 : mclassPriority.indexOf(b.class) == -1 ? -1 : mclassPriority.indexOf(a.class) - mclassPriority.indexOf(b.class);
|
|
499
|
-
};
|
|
500
|
-
return sorter;
|
|
501
|
-
}
|
|
502
|
-
function reshapeSortPriority(sortOption, labels) {
|
|
503
|
-
const l = labels;
|
|
504
|
-
let geneVariantsEntry;
|
|
505
|
-
for (const sp of sortOption.sortPriority) {
|
|
506
|
-
if (sp.types.includes("categorical")) {
|
|
507
|
-
if (!sp.label) sp.label = `For each dictionary variable, sort ${l.samples} by matching data`;
|
|
508
|
-
continue;
|
|
509
|
-
}
|
|
510
|
-
if (!sp.types?.includes("geneVariant")) continue;
|
|
511
|
-
if (!geneVariantsEntry) {
|
|
512
|
-
geneVariantsEntry = sp;
|
|
513
|
-
if (!sp.label) sp.label = `For each gene mutation, sort ${l.samples} by matching data`;
|
|
514
|
-
} else {
|
|
515
|
-
geneVariantsEntry.tiebreakers.push(...sp.tiebreakers);
|
|
516
|
-
sp.toBeDeleted = true;
|
|
517
|
-
}
|
|
518
|
-
}
|
|
519
|
-
for (const tb of geneVariantsEntry.tiebreakers) {
|
|
520
|
-
const origClone = structuredClone(tb);
|
|
521
|
-
if (tb.filter?.values?.find((v) => v.dt == dtfusionrna)) {
|
|
522
|
-
const defaults = {
|
|
523
|
-
label: `${l.Samples} with Fusion RNASeq > without`,
|
|
524
|
-
isOrdered: true,
|
|
525
|
-
disabled: false,
|
|
526
|
-
mayToggle: true
|
|
527
|
-
};
|
|
528
|
-
Object.assign(tb, defaults, origClone);
|
|
529
|
-
} else if (tb.filter?.values?.find((v) => v.dt == dtsnvindel)) {
|
|
530
|
-
const label = tb.order.includes(mclasscnvgain) || tb.order.includes(mclasscnvloss) ? `${l.Samples} with SSM + CNV > SSM only` : `${l.Samples} with mutations`;
|
|
531
|
-
const defaults = {
|
|
532
|
-
label,
|
|
533
|
-
isOrdered: true,
|
|
534
|
-
disabled: false,
|
|
535
|
-
mayToggle: true
|
|
536
|
-
};
|
|
537
|
-
Object.assign(tb, defaults, origClone);
|
|
538
|
-
} else if (tb.order.length == 2 && tb.order.includes(mclasscnvgain) && tb.order.includes(mclasscnvloss)) {
|
|
539
|
-
const defaults = {
|
|
540
|
-
label: `${l.Samples} with CNV only > without`,
|
|
541
|
-
filter: { values: [{ dt: dtcnv }] },
|
|
542
|
-
by: "class",
|
|
543
|
-
isOrdered: true,
|
|
544
|
-
disabled: false,
|
|
545
|
-
mayToggle: true
|
|
546
|
-
};
|
|
547
|
-
Object.assign(tb, defaults, origClone);
|
|
548
|
-
}
|
|
549
|
-
}
|
|
550
|
-
sortOption.sortPriority = sortOption.sortPriority.filter((sp) => !sp.toBeDeleted);
|
|
551
|
-
return sortOption;
|
|
552
|
-
}
|
|
553
|
-
|
|
554
|
-
export {
|
|
555
|
-
getSampleSorter,
|
|
556
|
-
getTermSorter,
|
|
557
|
-
getSortOptions,
|
|
558
|
-
getSampleGroupSorter,
|
|
559
|
-
getMclassSorter,
|
|
560
|
-
reshapeSortPriority
|
|
561
|
-
};
|
|
562
|
-
//# sourceMappingURL=chunk-NS2MZN3C.js.map
|
package/dist/chunk-NUA66GW7.js
DELETED
|
@@ -1,37 +0,0 @@
|
|
|
1
|
-
import {
|
|
2
|
-
DMR_SCAN_ELEMENT_TYPE
|
|
3
|
-
} from "./chunk-ME3HB3V6.js";
|
|
4
|
-
|
|
5
|
-
// plots/gsea/settings/defaults.ts
|
|
6
|
-
function isDmrScanRanking(opts) {
|
|
7
|
-
return opts?.elementType === DMR_SCAN_ELEMENT_TYPE || opts?.gsea_params?.daRequest?.element_type === DMR_SCAN_ELEMENT_TYPE;
|
|
8
|
-
}
|
|
9
|
-
function getDefaultGseaSettings(overrides = {}, opts = {}) {
|
|
10
|
-
const defaults = {
|
|
11
|
-
fdr_cutoff: 0.05,
|
|
12
|
-
num_permutations: 1e3,
|
|
13
|
-
top_genesets: 40,
|
|
14
|
-
pathway: opts?.gsea_params?.pathway ?? void 0,
|
|
15
|
-
geneset_name: null,
|
|
16
|
-
min_gene_set_size_cutoff: 0,
|
|
17
|
-
/* 500 only for a DMR scan's gene-body ranking, where blitzgsea's null fit is unstable above it.
|
|
18
|
-
The server enforces that ceiling on the library before the fit (genesetEnrichment.ts); this
|
|
19
|
-
default only keeps the table's own size filter consistent with it, and daRequest may not be
|
|
20
|
-
known yet when defaults are first built. Every other caller keeps 20,000, because lowering it
|
|
21
|
-
for them would silently drop large GO and Reactome sets from analyses that have always shown
|
|
22
|
-
them. */
|
|
23
|
-
max_gene_set_size_cutoff: isDmrScanRanking(opts) ? 500 : 2e4,
|
|
24
|
-
filter_non_coding_genes: true,
|
|
25
|
-
fdr_or_top: "top",
|
|
26
|
-
gsea_method: "blitzgsea"
|
|
27
|
-
};
|
|
28
|
-
if (JSON.parse(sessionStorage.getItem("optionalFeatures") || "{}")?.gsea_test) {
|
|
29
|
-
defaults.gsea_method = "cerno";
|
|
30
|
-
}
|
|
31
|
-
return Object.assign(defaults, overrides);
|
|
32
|
-
}
|
|
33
|
-
|
|
34
|
-
export {
|
|
35
|
-
getDefaultGseaSettings
|
|
36
|
-
};
|
|
37
|
-
//# sourceMappingURL=chunk-NUA66GW7.js.map
|