@sjcrh/proteinpaint-client 2.212.0 → 2.213.0

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (864) hide show
  1. package/dist/2dmaf-3FDGCUTK.js +1367 -0
  2. package/dist/AggMatrixInput-QA2FHMSY.js +406 -0
  3. package/dist/AggregateMatrix-XGVKDN2K.js +41 -0
  4. package/dist/AppHeader-NVLHCOVU.js +830 -0
  5. package/dist/BoxPlot-IVO7VBQZ.js +1208 -0
  6. package/dist/CorrelationVolcano-2XD5OH2S.js +617 -0
  7. package/dist/Cuminc-ECQ56PKO.js +1220 -0
  8. package/dist/DE-KWA2K24U.js +89 -0
  9. package/dist/DEinput-ZP6CYIRN.js +501 -0
  10. package/dist/DM-ME7CCC4E.js +90 -0
  11. package/dist/DifferentialAnalysis-6SIKR566.js +239 -0
  12. package/dist/Disco-LVRT7T3B.js +3389 -0
  13. package/dist/Disco.UI-GT64ZEK4.js +243 -0
  14. package/dist/DmrPlot-ZZYKJ4UH.js +362 -0
  15. package/dist/GB-WR6SENAZ.js +1392 -0
  16. package/dist/GSEA-U2GFOHWT.js +875 -0
  17. package/dist/GeneExpInput-CQSORTKI.js +42 -0
  18. package/dist/Geomap-CGJ7EIMD.js +84 -0
  19. package/dist/HicApp-DS3HC2G5.js +2245 -0
  20. package/dist/IDCViewer-6KWSZWZ7.js +10812 -0
  21. package/dist/NumBinaryEditor-BQVR2RDS.js +279 -0
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  23. package/dist/NumContEditor-6T6XFLAM.js +105 -0
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  25. package/dist/NumCustomBinEditor-Q2GJOFOH.js +33 -0
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  27. package/dist/NumDiscreteEditor-QFKPIRDW.js +170 -0
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  29. package/dist/NumRegularBinEditor-SLFPSTA3.js +33 -0
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  31. package/dist/NumSplineEditor-AEXNF6E4.js +210 -0
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  37. package/dist/ProteomeInput-AC5TRXHE.js +388 -0
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  44. package/dist/adSandbox-HZROPAPC.js +33 -0
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  54. package/dist/block.mds.expressionrank-W6GIHAAL.js +354 -0
  55. package/dist/block.mds.geneboxplot-GBP5N7AU.js +823 -0
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  73. package/dist/bubbleHeatmap-R2CNWOAJ.js +378 -0
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  142. package/dist/cohort-J3JNIMCT.js +70 -0
  143. package/dist/condition-A6VAD4OS.js +327 -0
  144. package/dist/controls-2R2OQAX2.js +34 -0
  145. package/dist/controls.btns-6AKLIWOG.js +9 -0
  146. package/dist/controls.config-UPE6TAHK.js +34 -0
  147. package/dist/correlation-Q6HYOUOX.js +95 -0
  148. package/dist/customdata.inputui-KQJKSQNI.js +284 -0
  149. package/dist/dataDownload-PYQX2BWN.js +329 -0
  150. package/dist/databrowser.ui-LPFKGVW3.js +425 -0
  151. package/dist/dictionary-GYN7OXWQ.js +113 -0
  152. package/dist/dnaMethylation-TSRHGNNY.js +33 -0
  153. package/dist/dnaMethylation.integration.spec-3YYSFVKK.js +198 -0
  154. package/dist/dofetch-4YRJUWLJ.js +48 -0
  155. package/dist/e2pca-G4AVRHQC.js +344 -0
  156. package/dist/ep-MHT3CLGK.js +1249 -0
  157. package/dist/expclust.gdc.spec-2TWLDD2S.js +302 -0
  158. package/dist/facet-4O65ZSBQ.js +519 -0
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  161. package/dist/geneExpClustering-LOLLER5C.js +244 -0
  162. package/dist/geneExpression-NP2N4CRU.js +310 -0
  163. package/dist/geneExpression-RWE7PBBD.js +33 -0
  164. package/dist/geneExpression.unit.spec-MBE6YVKY.js +128 -0
  165. package/dist/geneORA-ZWZCCBL7.js +273 -0
  166. package/dist/geneRanking-UZXH5SLT.js +548 -0
  167. package/dist/geneVariant-MULXYJ7M.js +36 -0
  168. package/dist/geneVariant-ZPINPLRP.js +289 -0
  169. package/dist/geneVariant.integration.spec-6DNKP22T.js +503 -0
  170. package/dist/genefusion.ui-S4BPNRIO.js +303 -0
  171. package/dist/geneset-LZNALH2H.js +203 -0
  172. package/dist/genomeBrowser.spec-JOIKBWVC.js +276 -0
  173. package/dist/grin2-GFZ5REPY.js +949 -0
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  175. package/dist/hierCluster-DCESQECE.js +55 -0
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  177. package/dist/hierCluster.config-DBQYJXML.js +36 -0
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  179. package/dist/hierCluster.interactivity-EKKKYVEP.js +49 -0
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  187. package/dist/leftlabel.sample-CRMQSNCJ.js +258 -0
  188. package/dist/lollipop-XLPUIZBA.js +166 -0
  189. package/dist/maf-LPXQMGJC.js +455 -0
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  206. package/dist/mds.samplescatterplot-W3TCPYHS.js +1545 -0
  207. package/dist/mds.survivalplot-EYAA5IO3.js +477 -0
  208. package/dist/multivalue-GGM5DFPD.js +83 -0
  209. package/dist/oncomatrix-MVLDAB6I.js +290 -0
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  220. package/dist/profileForms-WU7UNK7Y.js +941 -0
  221. package/dist/profilePlot-KW7UITCT.js +49 -0
  222. package/dist/proteinView-ET75MKLU.js +1357 -0
  223. package/dist/proteomeCohortCompare-SDX5D26O.js +912 -0
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  805. /package/dist/{samplelst-TH6IBDVG.js.map → samplelst-ZB23PILZ.js.map} +0 -0
  806. /package/dist/{samplematrix-RPCWT33H.js.map → samplematrix-CQAB5PVO.js.map} +0 -0
  807. /package/dist/{sc-BFBHBAXF.js.map → sc-JOIUUG4I.js.map} +0 -0
  808. /package/dist/{scatter-L6R6J2LC.js.map → scatter-DCX72P3N.js.map} +0 -0
  809. /package/dist/{scatter-3IC6HOT7.js.map → scatter-JXBGEKLF.js.map} +0 -0
  810. /package/dist/{selectGenomeWithTklst-3ZK7FIOP.js.map → selectGenomeWithTklst-EZTHPCBB.js.map} +0 -0
  811. /package/dist/{singleCellCellType-CLJFCBV6.js.map → singleCellCellType-BOQTDUZA.js.map} +0 -0
  812. /package/dist/{singleCellCellType.unit.spec-W32PSTRO.js.map → singleCellCellType.unit.spec-3HUF7VWW.js.map} +0 -0
  813. /package/dist/{singleCellGeneExpression-L6MG37XE.js.map → singleCellGeneExpression-UBTHLFRN.js.map} +0 -0
  814. /package/dist/{singleCellGeneExpression.unit.spec-SF46JHCU.js.map → singleCellGeneExpression.unit.spec-YM6EQB3E.js.map} +0 -0
  815. /package/dist/{singleCellNumericValue-7QXK6KVZ.js.map → singleCellNumericValue-53T6WOHJ.js.map} +0 -0
  816. /package/dist/{singleCellNumericValue.unit.spec-VC7NQYM2.js.map → singleCellNumericValue.unit.spec-SYSMD5IW.js.map} +0 -0
  817. /package/dist/{singleCellPlot-5TRNRKPN.js.map → singleCellPlot-3V47EUB4.js.map} +0 -0
  818. /package/dist/{singlecell-I4PHM2LZ.js.map → singlecell-AFGFONXY.js.map} +0 -0
  819. /package/dist/{singlecell-2YV3UAIQ.js.map → singlecell-VZI3LEUT.js.map} +0 -0
  820. /package/dist/{snp-ZIA4YWCZ.js.map → snp-IPIYL7OY.js.map} +0 -0
  821. /package/dist/{snp.unit.spec-MVQHY4WJ.js.map → snp.unit.spec-OC5JHCXR.js.map} +0 -0
  822. /package/dist/{snplocus-GM6IEDPR.js.map → snplocus-DSGUSGUP.js.map} +0 -0
  823. /package/dist/{spliceevent.a53ss.diagram-ZFQDHHPY.js.map → spliceevent.a53ss.diagram-RNAJHS4P.js.map} +0 -0
  824. /package/dist/{spliceevent.exonskip.diagram-ZK6JOUMU.js.map → spliceevent.exonskip.diagram-YWRATK46.js.map} +0 -0
  825. /package/dist/{spliceevent.noeventdiagram-YKTF2VZE.js.map → spliceevent.noeventdiagram-6ZJRJ4QZ.js.map} +0 -0
  826. /package/dist/{ssGSEA-FDN4CH2Y.js.map → ssGSEA-IWCC6JDL.js.map} +0 -0
  827. /package/dist/{ssGSEA.unit.spec-YEUJBT6Z.js.map → ssGSEA.unit.spec-3TKDENWO.js.map} +0 -0
  828. /package/dist/{stattable-WIZRSKPH.js.map → stattable-EXOWMETP.js.map} +0 -0
  829. /package/dist/{studyCatalog-X2IGVJ26.js.map → studyCatalog-OAGHQXKY.js.map} +0 -0
  830. /package/dist/{summarizeCnvGeneexp-H7A5SI3R.js.map → summarizeCnvGeneexp-K6XO5YEP.js.map} +0 -0
  831. /package/dist/{summarizeGeneexpSurvival-GJF6VD2S.js.map → summarizeGeneexpSurvival-WTAGCCU4.js.map} +0 -0
  832. /package/dist/{summarizeMutationCnv-WQLMD2TR.js.map → summarizeMutationCnv-QKIDS3LI.js.map} +0 -0
  833. /package/dist/{summarizeMutationDiagnosis-3S52IDWF.js.map → summarizeMutationDiagnosis-ACFWADSQ.js.map} +0 -0
  834. /package/dist/{summarizeMutationSurvival-NTQIUNW7.js.map → summarizeMutationSurvival-XPFPN4N5.js.map} +0 -0
  835. /package/dist/{summary-LMRFRKKI.js.map → summary-VCU2NTIZ.js.map} +0 -0
  836. /package/dist/{summary.integration.spec-KQMZKSEQ.js.map → summary.integration.spec-2DE653PH.js.map} +0 -0
  837. /package/dist/{summaryInput-NNHZVHQA.js.map → summaryInput-GO75OPLA.js.map} +0 -0
  838. /package/dist/{sunburst-ICUSGIWV.js.map → sunburst-BSCFRYSV.js.map} +0 -0
  839. /package/dist/{survival-K44Q2HAC.js.map → survival-BEP7JNML.js.map} +0 -0
  840. /package/dist/{survival-K5YBNNVE.js.map → survival-XUO2D6CX.js.map} +0 -0
  841. /package/dist/{survival.integration.spec-4LRJW2V2.js.map → survival.integration.spec-EO5KAFDQ.js.map} +0 -0
  842. /package/dist/{svgraph-U7MS7YEM.js.map → svgraph-YGXOB3QY.js.map} +0 -0
  843. /package/dist/{svmr-2JGDBPAI.js.map → svmr-MATMMI4E.js.map} +0 -0
  844. /package/dist/{table-CBWOHYW6.js.map → table-DFSX7XYJ.js.map} +0 -0
  845. /package/dist/{termCollection-JFGGXVFI.js.map → termCollection-GKPC4K2O.js.map} +0 -0
  846. /package/dist/{termCollection-VE3FFL6V.js.map → termCollection-ZUJFB7YB.js.map} +0 -0
  847. /package/dist/{termCollection.unit.spec-XQQTDV4A.js.map → termCollection.unit.spec-YE7IKC6S.js.map} +0 -0
  848. /package/dist/{termCollectionFractionSelection-TFGF27GR.js.map → termCollectionFractionSelection-DLWXUEEN.js.map} +0 -0
  849. /package/dist/{termCollectionFractionSelection.unit.spec-MKGG4JBC.js.map → termCollectionFractionSelection.unit.spec-N2LNHIWC.js.map} +0 -0
  850. /package/dist/{termInfo-J5Q7Y763.js.map → termInfo-PZ7UDA5C.js.map} +0 -0
  851. /package/dist/{tk-74SGUUZY.js.map → tk-PHTWQHVV.js.map} +0 -0
  852. /package/dist/{tk-K4JFYIZY.js.map → tk-RNUMIS5P.js.map} +0 -0
  853. /package/dist/{tp.ui-727EXXMT.js.map → tp.ui-A52OBFJD.js.map} +0 -0
  854. /package/dist/{tvs.dt-YB2C3T33.js.map → tvs.dt-SQSP3UXH.js.map} +0 -0
  855. /package/dist/{tvs.dtcnv.categorical-NOWMZOE5.js.map → tvs.dtcnv.categorical-3IWQMUEM.js.map} +0 -0
  856. /package/dist/{tvs.dtcnv.continuous-3KWUNU76.js.map → tvs.dtcnv.continuous-ZD5WM32O.js.map} +0 -0
  857. /package/dist/{tvs.dtfusion-NOJSTABU.js.map → tvs.dtfusion-G47Z7NP3.js.map} +0 -0
  858. /package/dist/{tvs.dtitd-OD5B377P.js.map → tvs.dtitd-57PSTVRM.js.map} +0 -0
  859. /package/dist/{tvs.dtsnvindel-WIQMZTRH.js.map → tvs.dtsnvindel-CS3ZVFWN.js.map} +0 -0
  860. /package/dist/{tvs.dtsv-HPERDN3R.js.map → tvs.dtsv-LNWDVFCR.js.map} +0 -0
  861. /package/dist/{tvs.samplelst-TC2Z7Z35.js.map → tvs.samplelst-EMZOR4SY.js.map} +0 -0
  862. /package/dist/{tvs.termCollection-F64BHWAL.js.map → tvs.termCollection-RX5ASV3N.js.map} +0 -0
  863. /package/dist/{vocabulary-ZOYF2VHS.js.map → vocabulary-JVAACQPU.js.map} +0 -0
  864. /package/dist/{wsi.direct-Z5YUZEXG.js.map → wsi.direct-J4SNIUUW.js.map} +0 -0
@@ -0,0 +1,243 @@
1
+ import {
2
+ keyupEnter
3
+ } from "./chunk-QI6X4V43.js";
4
+ import {
5
+ get_bin_label,
6
+ get_bin_range_equation
7
+ } from "./chunk-YU7CVG4B.js";
8
+ import {
9
+ toStoredUnit,
10
+ toUserUnit
11
+ } from "./chunk-W5J3LTYS.js";
12
+
13
+ // termsetting/handlers/NumCustomBinEditor.ts
14
+ var NumCustomBinEditor = class {
15
+ constructor(editHandler) {
16
+ this.dom = {};
17
+ this.editHandler = editHandler;
18
+ this.opts = editHandler.opts;
19
+ this.tw = editHandler.tw;
20
+ this.termsetting = editHandler.termsetting;
21
+ }
22
+ /* bin boundaries are stored in the term's own unit but entered and shown in its user-facing one.
23
+ both are identity functions unless the term declares valueConversion{} */
24
+ toDisplay(v) {
25
+ return toUserUnit(v, this.tw.term);
26
+ }
27
+ toStored(v) {
28
+ return toStoredUnit(v, this.tw.term);
29
+ }
30
+ async render(div) {
31
+ this.tw = this.editHandler.tw;
32
+ const isRemounting = !!this.dom.inputsDiv && this.editHandler.dom.binsDiv?.node().contains(this.dom.inputsDiv.node());
33
+ if (!isRemounting) this.q = this.getDefaultQ();
34
+ await this.editHandler.handler.density.setBinLines(this.getBoundaryOpts());
35
+ if (isRemounting) return;
36
+ if (this.dom.inputsDiv) {
37
+ this.dom.inputsDiv.remove();
38
+ delete this.dom.inputsDiv;
39
+ }
40
+ this.dom.inputsDiv = div.append("div").style("display", "flex").style("width", "100%");
41
+ this.renderCustomBinInputs();
42
+ }
43
+ getBoundaryOpts() {
44
+ return {
45
+ values: this.q.lst.slice(1).map((bin) => ({ x: this.toDisplay(bin.startunbounded ? bin.stop : bin.start), isDraggable: true })),
46
+ // the dragged value arrives in display units, matching what the textarea holds
47
+ callback: (d, value) => {
48
+ const boundaryValues = this.q.lst.slice(1).map((d2) => "start" in d2 ? this.toDisplay(d2.start) : "");
49
+ boundaryValues[d.index] = value;
50
+ this.dom.customBinBoundaryInput.property("value", boundaryValues.join("\n"));
51
+ this.handleInputChange("drag");
52
+ return 0;
53
+ }
54
+ };
55
+ }
56
+ getDefaultQ() {
57
+ if (this.tw.q.mode == "discrete" && this.tw.q.type == "custom-bin") {
58
+ const copy = JSON.parse(JSON.stringify(this.tw.q));
59
+ copy.lst.forEach((bin) => {
60
+ if (!bin.label) bin.label = get_bin_label(bin, this.tw.q, this.tw.term.valueConversion);
61
+ bin.range = get_bin_range_equation(bin, this.tw.q, this.tw.term.valueConversion);
62
+ });
63
+ return copy;
64
+ }
65
+ const { min, max } = this.editHandler.handler.density_data;
66
+ const defaultCustomBoundary = (
67
+ /* when no sample is annotated by this term,
68
+ minvalue and maxvalue are both null
69
+ setting defaultCustomBoundary to arbitrary "0" will allow existing UI to work
70
+ but remains to be evaluated if is really okay to use 0
71
+ */
72
+ !Number.isFinite(min) || !Number.isFinite(max) ? 0 : (
73
+ // minvalue and maxvalue is valid number
74
+ max != min ? min + (max - min) / 2 : max
75
+ )
76
+ );
77
+ const firstBin = {
78
+ startunbounded: true,
79
+ startinclusive: false,
80
+ stopinclusive: false,
81
+ stop: +defaultCustomBoundary.toFixed(this.tw.term.type == "integer" ? 0 : 2)
82
+ };
83
+ const lastBin = {
84
+ stopunbounded: true,
85
+ startinclusive: true,
86
+ stopinclusive: false,
87
+ start: +defaultCustomBoundary.toFixed(this.tw.term.type == "integer" ? 0 : 2)
88
+ };
89
+ return {
90
+ mode: "discrete",
91
+ type: "custom-bin",
92
+ lst: [
93
+ // Type '{ label: any; range: any; startunbounded: boolean; startinclusive: boolean; stopinclusive: boolean; stop: number; }' is not assignable to type 'StartUnboundedBin | FullyBoundedBin'.
94
+ // Property 'start' is missing in type '{ label: any; range: any; startunbounded: boolean; startinclusive: boolean; stopinclusive: boolean; stop: number; }' but required in type 'FullyBoundedBin'.
95
+ {
96
+ ...firstBin,
97
+ label: get_bin_label(firstBin, this.tw.q, this.tw.term.valueConversion),
98
+ range: get_bin_range_equation(firstBin, this.tw.q, this.tw.term.valueConversion)
99
+ },
100
+ {
101
+ ...lastBin,
102
+ label: get_bin_label(lastBin, this.tw.q, this.tw.term.valueConversion),
103
+ range: get_bin_range_equation(lastBin, this.tw.q, this.tw.term.valueConversion)
104
+ }
105
+ //satisfies StopUnboundedBin
106
+ ]
107
+ };
108
+ }
109
+ /******************* Functions for Numerical Custom size bins *******************/
110
+ renderCustomBinInputs() {
111
+ const q = this.q;
112
+ const boundaryDiv = this.dom.inputsDiv.append("div").style("margin-right", "20px");
113
+ this.dom.rangeAndLabelDiv = this.dom.inputsDiv.append("div");
114
+ boundaryDiv.append("div").style("margin-bottom", "5px").style("color", "rgb(136, 136, 136)").text("Bin boundaries");
115
+ this.dom.customBinBoundaryInput = boundaryDiv.append("textarea").style("width", "100px").style("height", "70px").text(
116
+ q.lst.slice(1).map((d) => "start" in d ? this.toDisplay(d.start) : "").join("\n")
117
+ ).on("change", () => this.handleInputChange()).on("keyup", async (event) => {
118
+ if (!keyupEnter(event) && event.key != 8 && event.key != "Enter") return;
119
+ if (!this.dom.inputsDiv.selectAll("input").node().value) return;
120
+ this.handleInputChange();
121
+ });
122
+ boundaryDiv.append("div").style("font-size", ".6em").style("margin-left", "1px").style("color", "#858585").html("Enter numeric values </br>seperated by ENTER");
123
+ this.renderBoundaryInputDivs();
124
+ }
125
+ renderBoundaryInputDivs() {
126
+ const data = this.q.lst;
127
+ const holder = this.dom.rangeAndLabelDiv;
128
+ holder.selectAll("*").remove();
129
+ const grid = holder.append("div").style("display", "grid").style("grid-template-columns", "auto auto").style("column-gap", "20px").style("align-items", "center");
130
+ grid.append("div").style("margin-bottom", "3px").style("color", "rgb(136, 136, 136)").text("Range");
131
+ grid.append("div").style("margin-bottom", "3px").style("color", "rgb(136, 136, 136)").text("Bin label");
132
+ for (const d of data) {
133
+ grid.append("div").attr("name", "range").html(d.range);
134
+ grid.append("div").append("input").attr("type", "text").style("margin", "2px 0px").property("value", d.label).on("change", function() {
135
+ d.label = this.value;
136
+ });
137
+ }
138
+ this.dom.customBinRanges = this.dom.inputsDiv.selectAll('div[name="range"]').data(data);
139
+ this.dom.customBinLabelInput = this.dom.inputsDiv.selectAll("input").data(data);
140
+ }
141
+ handleInputChange(eventType = "") {
142
+ const self = this.tw;
143
+ const inputs = this.dom.inputsDiv.selectAll("input");
144
+ inputs.property("value", "");
145
+ const data = this.processCustomBinInputs();
146
+ if (data == void 0) {
147
+ return;
148
+ }
149
+ if (self.q.hiddenValues) this.tw.q.hiddenValues = self.q.hiddenValues;
150
+ if (this.binsChanged(data, this.q.lst)) {
151
+ this.q.lst = data;
152
+ }
153
+ this.renderBoundaryInputDivs();
154
+ if (eventType != "drag") this.editHandler.handler.density.setBinLines(this.getBoundaryOpts());
155
+ }
156
+ binsChanged(data, qlst) {
157
+ if (data.length != qlst.length) return true;
158
+ if (Object.keys(data[0]).length !== Object.keys(qlst[0]).length) return true;
159
+ for (const [i, bin] of qlst.entries()) {
160
+ for (const k of Object.keys(bin)) {
161
+ if (bin[k] && bin[k] !== data[i][k]) {
162
+ return true;
163
+ }
164
+ }
165
+ }
166
+ return false;
167
+ }
168
+ processCustomBinInputs() {
169
+ const self = this.termsetting;
170
+ const startinclusive = this.editHandler.boundaryInclusion == "startinclusive";
171
+ const stopinclusive = this.editHandler.boundaryInclusion == "stopinclusive";
172
+ const inputs = this.dom.inputsDiv.node().querySelectorAll("input");
173
+ const inputData = this.dom.customBinBoundaryInput.property("value").split("\n").filter((d) => d != "" && !isNaN(d));
174
+ const trackBins = new Set(inputData);
175
+ if (!trackBins.size) return this.tw.q.lst;
176
+ const sortedBins = Array.from(trackBins).map((v) => this.toStored(Number(v))).sort((a, b) => a - b);
177
+ const data = [
178
+ // first bin: StartUnbounded type
179
+ {
180
+ startunbounded: true,
181
+ stop: sortedBins[0],
182
+ startinclusive: false,
183
+ stopinclusive,
184
+ label: inputs[0].value
185
+ }
186
+ ];
187
+ if (!data[0].label) data[0].label = get_bin_label(data[0], self.q, self.term.valueConversion);
188
+ if (!data[0].range) data[0].range = get_bin_range_equation(data[0], self.q, self.term.valueConversion);
189
+ for (const [i, d] of sortedBins.entries()) {
190
+ let bin;
191
+ const label = inputs[i + 1]?.value || "";
192
+ if (i !== trackBins.size - 1) {
193
+ bin = {
194
+ start: +d,
195
+ startinclusive,
196
+ stopinclusive,
197
+ stop: sortedBins[i + 1],
198
+ label
199
+ //range: ''
200
+ };
201
+ } else {
202
+ bin = {
203
+ start: +d,
204
+ startinclusive,
205
+ stopinclusive: false,
206
+ stopunbounded: true,
207
+ label
208
+ //range: ''
209
+ };
210
+ }
211
+ if (bin.label === "" || bin.label === void 0) bin.label = get_bin_label(bin, self.q, self.term.valueConversion);
212
+ if (bin.range === "" || bin.range === void 0)
213
+ bin.range = get_bin_range_equation(bin, self.q, self.term.valueConversion);
214
+ data.push(bin);
215
+ }
216
+ return data;
217
+ }
218
+ getEditedQ(destroyDom = true) {
219
+ const lst = this.processCustomBinInputs();
220
+ if (destroyDom) {
221
+ for (const name of Object.keys(this.dom)) {
222
+ this.dom[name].remove();
223
+ delete this.dom[name];
224
+ }
225
+ }
226
+ return {
227
+ mode: "discrete",
228
+ type: "custom-bin",
229
+ lst
230
+ };
231
+ }
232
+ undoEdits() {
233
+ this.q = this.getDefaultQ();
234
+ this.dom.inputsDiv.selectAll("*").remove();
235
+ this.renderCustomBinInputs();
236
+ this.editHandler.handler.density.setBinLines(this.getBoundaryOpts());
237
+ }
238
+ };
239
+
240
+ export {
241
+ NumCustomBinEditor
242
+ };
243
+ //# sourceMappingURL=chunk-OB3S6QYD.js.map
@@ -0,0 +1,55 @@
1
+ import {
2
+ colorinframe
3
+ } from "./chunk-QI6X4V43.js";
4
+ import {
5
+ IN_frame,
6
+ OUT_frame
7
+ } from "./chunk-57Z4VYLM.js";
8
+
9
+ // src/spliceevent.phrase.js
10
+ function spliceevent_phrase_default(evt) {
11
+ const htmls = [];
12
+ if (evt.isaltexon || evt.isskipexon) {
13
+ const exonstart = Math.min(...evt.skippedexon);
14
+ const exonstop = Math.max(...evt.skippedexon);
15
+ htmls.push(
16
+ '<div style="display:inline-block">' + (exonstart == exonstop ? "exon " + (exonstart + 1) : "exons " + (exonstart + 1) + "-" + (exonstop + 1)) + " " + (evt.isaltexon ? "alternative usage" : "skipping") + "</div>"
17
+ );
18
+ if (evt.isaltexon) {
19
+ htmls.push(
20
+ "<div class=sja_tinylogo_body>" + evt.gmB.isoform + ", " + evt.gmA.isoform + "</div><div class=sja_tinylogo_head>ISOFORMS</div>"
21
+ );
22
+ } else {
23
+ htmls.push("<div class=sja_tinylogo_body>" + evt.gm.isoform + "</div><div class=sja_tinylogo_head>ISOFORM</div>");
24
+ }
25
+ if (evt.junctionB.data) {
26
+ htmls.push(
27
+ "<div class=sja_tinylogo_body>" + evt.junctionB.data.length + "</div><div class=sja_tinylogo_head>SAMPLE" + (evt.junctionB.data.length > 1 ? "S" : "") + "</div>"
28
+ );
29
+ }
30
+ htmls.push("<div class=sja_tinylogo_body>" + evt.percentage + " %</div><div class=sja_tinylogo_head>PERCENT</div>");
31
+ if (evt.framenocheck) {
32
+ if (evt.utr3) {
33
+ htmls.push(`<div class=sja_tinylogo_body style="background-color:#ededed">3' UTR</div>`);
34
+ } else if (evt.utr5) {
35
+ htmls.push(`<div class=sja_tinylogo_body style="background-color:#ededed">5' UTR</div>`);
36
+ }
37
+ } else if (evt.frame == IN_frame) {
38
+ htmls.push(
39
+ '<div class=sja_tinylogo_body style="background-color:' + colorinframe + ';color:white">IN</div><div class=sja_tinylogo_head>FRAME</div>'
40
+ );
41
+ } else if (evt.frame == OUT_frame) {
42
+ htmls.push("<div class=sja_tinylogo_body>OUT</div><div class=sja_tinylogo_head>FRAME</div>");
43
+ } else {
44
+ htmls.push("<div class=sja_tinylogo_body>?</div><div class=sja_tinylogo_head>FRAME</div>");
45
+ }
46
+ } else {
47
+ return "unknown event type!!";
48
+ }
49
+ return htmls.join(" ");
50
+ }
51
+
52
+ export {
53
+ spliceevent_phrase_default
54
+ };
55
+ //# sourceMappingURL=chunk-OLV3Q6TN.js.map
@@ -0,0 +1,263 @@
1
+ import {
2
+ Matrix
3
+ } from "./chunk-MIG3QAYD.js";
4
+ import {
5
+ hierCluster_renderers_exports
6
+ } from "./chunk-7AOA5WZY.js";
7
+ import {
8
+ hierCluster_interactivity_exports
9
+ } from "./chunk-3BBUXNES.js";
10
+ import {
11
+ filterJoin,
12
+ getNormalRoot
13
+ } from "./chunk-QI6X4V43.js";
14
+ import {
15
+ clusterMethodLst,
16
+ distanceMethodLst,
17
+ dofetch3
18
+ } from "./chunk-YU7CVG4B.js";
19
+ import {
20
+ TermTypes2Dt,
21
+ dictionaryNumericTypes
22
+ } from "./chunk-RU2UHH7M.js";
23
+ import {
24
+ colorScaleMap
25
+ } from "./chunk-57Z4VYLM.js";
26
+ import {
27
+ deepEqual,
28
+ getCompInit
29
+ } from "./chunk-HBNB5TRH.js";
30
+ import {
31
+ extent,
32
+ linear
33
+ } from "./chunk-4OLM3KSB.js";
34
+
35
+ // plots/matrix/hierCluster.js
36
+ var HierCluster = class _HierCluster extends Matrix {
37
+ static type = "hierCluster";
38
+ constructor(opts) {
39
+ super(opts);
40
+ this.type = _HierCluster.type;
41
+ this.chartType = _HierCluster.type;
42
+ }
43
+ async init(appState) {
44
+ await super.init(appState);
45
+ this.maySetSandboxHeader(appState);
46
+ this.hcClipId = this.seriesClipId + "-hc";
47
+ this.dom.hcClipRect = this.dom.svg.select("defs").append("clipPath").attr("id", this.hcClipId).attr("clipPathUnits", "userSpaceOnUse").append("rect").attr("display", "block");
48
+ this.dom.topDendrogram = this.dom.svg.insert("g", "g").attr("clip-path", `url(#${this.hcClipId})`).append("g").attr("class", "sjpp-matrix-dendrogram").attr("data-testid", "hierCluster_top_dendrogram").on("click", (event) => {
49
+ const clickedClusterId = this.getClusterFromTopDendrogram(event);
50
+ if (clickedClusterId) {
51
+ this.clickedClusterIds = this.getAllChildrenClusterIds(clickedClusterId);
52
+ this.clickedClusterIds.push(clickedClusterId);
53
+ const clickedCluster = this.hierClusterData.clustering.col.mergedClusters.get(clickedClusterId);
54
+ const clickedClusterSampleNames = clickedCluster.children.map((c) => c.name);
55
+ this.addSelectedSamplesOptions(clickedClusterSampleNames, event);
56
+ } else {
57
+ delete this.clickedClusterIds;
58
+ }
59
+ if (this.clickedLeftClusterIds) {
60
+ delete this.clickedLeftClusterIds;
61
+ this.plotDendrogramHclust();
62
+ } else this.plotDendrogramHclust("top");
63
+ });
64
+ this.dom.leftDendrogram = this.dom.svg.insert("g", "g").attr("class", "sjpp-matrix-dendrogram").attr("data-testid", "hierCluster_left_dendrogram").on("click", (event) => {
65
+ const clickedLeftClusterId = this.getClusterFromLeftDendrogram(event);
66
+ if (clickedLeftClusterId) {
67
+ this.clickedLeftClusterIds = this.getAllChildrenClusterIds(clickedLeftClusterId, true);
68
+ this.clickedLeftClusterIds.push(clickedLeftClusterId);
69
+ const clickedLeftCluster = this.hierClusterData.clustering.row.mergedClusters.get(clickedLeftClusterId);
70
+ const clickedLeftClusterRowsNames = clickedLeftCluster.children.map((c) => c.name);
71
+ this.addSelectedRowsOptions(clickedLeftClusterRowsNames, event);
72
+ } else {
73
+ delete this.clickedLeftClusterIds;
74
+ }
75
+ if (this.clickedClusterIds) {
76
+ delete this.clickedClusterIds;
77
+ this.plotDendrogramHclust();
78
+ } else this.plotDendrogramHclust("left");
79
+ });
80
+ }
81
+ async setHierClusterData(_data = {}) {
82
+ this.prevServerData = this.currServerData;
83
+ const [d, twlst] = await this.requestData({});
84
+ if (d.error) throw d.error;
85
+ this.currServerData = structuredClone(d);
86
+ if (!deepEqual(this.prevServerData, this.currServerData)) {
87
+ delete this.clickedClusterIds;
88
+ delete this.clickedLeftClusterIds;
89
+ }
90
+ const s = this.settings.hierCluster;
91
+ if (!d.clustering) {
92
+ if (d.gene) {
93
+ throw `Cannot do clustering: data is only available for 1 gene (${d.gene}). Try again by adding more genes.`;
94
+ }
95
+ }
96
+ this.hierClusterData = d;
97
+ const c = this.hierClusterData.clustering;
98
+ this.setHierColorScale(c);
99
+ const samples = {};
100
+ for (const [i, column] of c.col.order.entries()) {
101
+ samples[column.name] = { sample: column.name };
102
+ for (const [j, row] of c.row.order.entries()) {
103
+ const tw = twlst.find((tw2) => tw2.$id === row.name || tw2.id === row.name);
104
+ const value = c.matrix[j][i];
105
+ samples[column.name][tw.$id] = {
106
+ key: tw.term.name,
107
+ values: [
108
+ {
109
+ sample: column.name,
110
+ dt: TermTypes2Dt[this.state.config.dataType],
111
+ label: s.termGroupName,
112
+ // gene: tw.term.name,
113
+ // chr: tw.term.chr,
114
+ // pos: `${tw.term.start}-${tw.term.stop}`,
115
+ value
116
+ // the color will be computed in matrix.cells, so that
117
+ // it can get updated even when there are no nonsetting state diff
118
+ }
119
+ ]
120
+ };
121
+ }
122
+ }
123
+ this.hcTermNameOrder = this.settings.hierCluster.sortClusterRows == "asListed" ? twlst.map((t) => t.term.name) : this.settings.hierCluster.sortClusterRows == "byName" ? twlst.map((t) => t.term.name).sort() : dictionaryNumericTypes.has(this.config.dataType) ? c.row.order.map((row) => twlst.find((t) => t.$id == row.name || t.term.id == row.name)?.term.name) : c.row.order.map((row) => twlst.find((t) => t.$id == row.name)?.term.name);
124
+ if (this.hcTermNameOrder.includes(void 0)) throw `unable to map row.name to term.name`;
125
+ this.hcTermSorter = (a, b) => {
126
+ const i = this.hcTermNameOrder.indexOf(a.tw.term.name);
127
+ const j = this.hcTermNameOrder.indexOf(b.tw.term.name);
128
+ if (i == -1 && j == -1) return 0;
129
+ if (i == -1) return 1;
130
+ if (j == -1) return -1;
131
+ return i - j;
132
+ };
133
+ this.hcSampleNameOrder = c.col.order.map((col) => col.name);
134
+ this.hcSampleSorter = (a, b) => {
135
+ const i = this.hcSampleNameOrder.indexOf(a.sample);
136
+ const j = this.hcSampleNameOrder.indexOf(b.sample);
137
+ if (i == -1 && j == -1) return 0;
138
+ if (i == -1) return 1;
139
+ if (j == -1) return -1;
140
+ return i - j;
141
+ };
142
+ const byTermId = {};
143
+ for (const tw of twlst) {
144
+ if (d.byTermId?.[tw.term.name]) byTermId[tw.$id] = d.byTermId[tw.term.name];
145
+ }
146
+ this.hierClusterSamples = {
147
+ refs: { byTermId, bySampleId: d.bySampleId },
148
+ lst: c.col.order.map((c2) => samples[c2.name]),
149
+ samples,
150
+ removedHierClusterTerms: d.removedHierClusterTerms
151
+ };
152
+ }
153
+ async requestData() {
154
+ const body = this.currRequestOpts?.hierCluster || this.getHCRequestBody(this.state);
155
+ const twlst = this.hcTermGroup.lst;
156
+ const data = await dofetch3("termdb/cluster", { body, signal: this.api.getAbortSignal?.() });
157
+ return [data, twlst];
158
+ }
159
+ getHCRequestBody(state) {
160
+ this.hcTermGroup = this.config.termgroups.find((grp) => grp.type == "hierCluster") || this.termOrder?.find((t) => t.grp.type == "hierCluster")?.grp;
161
+ const s = state.config.settings.hierCluster;
162
+ const dictionaryLegendFilter = {
163
+ type: "tvslst",
164
+ in: true,
165
+ join: "and",
166
+ lst: state.config.legendValueFilter.lst.filter((f) => !f.tvs.legendFilterType)
167
+ };
168
+ const terms = this.getClusterRowTermsAsParameter();
169
+ if (!terms.length) throw "no data";
170
+ if (!clusterMethodLst.find((i) => i.value == s.clusterMethod)) throw "Invalid cluster method";
171
+ if (!distanceMethodLst.find((i) => i.value == s.distanceMethod)) throw "Invalid distance method";
172
+ const body = {
173
+ genome: state.vocab.genome,
174
+ dslabel: state.vocab.dslabel,
175
+ dataType: state.config.dataType,
176
+ clusterMethod: s.clusterMethod,
177
+ distanceMethod: s.distanceMethod,
178
+ zScoreTransformation: s.zScoreTransformation,
179
+ terms,
180
+ filter: getNormalRoot(filterJoin([state.filter, dictionaryLegendFilter])),
181
+ filter0: state.filter0
182
+ };
183
+ if (state.config.dataType == "proteomeAbundance") {
184
+ body.proteomeDetails = {
185
+ organism: state.config.proteomeDetails?.organism,
186
+ assay: state.config.proteomeDetails?.assay,
187
+ cohort: state.config.proteomeDetails?.cohort
188
+ };
189
+ }
190
+ return body;
191
+ }
192
+ combineData() {
193
+ if (!this.hierClusterSamples) return;
194
+ const d = this.data;
195
+ const removedHierClusterTerms = this.hierClusterSamples.removedHierClusterTerms;
196
+ const samples = {};
197
+ const lst = [];
198
+ for (const sampleId in this.hierClusterSamples.samples) {
199
+ const s = this.hierClusterSamples.samples[sampleId];
200
+ samples[sampleId] = s;
201
+ lst.push(s);
202
+ if (sampleId in d.samples) Object.assign(s, d.samples[sampleId]);
203
+ const _ref_ = this.hierClusterSamples.refs.bySampleId[sampleId] || {};
204
+ if (!s._ref_) s._ref_ = _ref_;
205
+ else Object.assign(s._ref_, _ref_);
206
+ }
207
+ const t = this.hierClusterSamples.refs.byTermId;
208
+ for (const $id of Object.keys(t)) {
209
+ d.refs.byTermId[$id] = Object.assign({}, d.refs.byTermId[$id] || {}, t[$id]);
210
+ }
211
+ this.data = { samples, lst, refs: d.refs, removedHierClusterTerms };
212
+ }
213
+ setHierColorScale(c) {
214
+ const hc = this.settings.hierCluster;
215
+ const scale = linear(colorScaleMap[hc.colorScale].domain, colorScaleMap[hc.colorScale].range).clamp(true);
216
+ const globalMinMaxes = [];
217
+ for (const row of c.matrix) {
218
+ globalMinMaxes.push(...extent(row));
219
+ }
220
+ const absMax = Math.min(hc.zScoreCap, Math.max(...extent(globalMinMaxes).map(Math.abs)));
221
+ const [min, max] = hc.zScoreTransformation ? [-absMax, absMax] : [Math.min(...globalMinMaxes), Math.max(...globalMinMaxes)];
222
+ this.hierClusterValues = { scale, min, max };
223
+ }
224
+ getValueColor(value) {
225
+ const hc = this.settings.hierCluster;
226
+ if (hc.zScoreTransformation) {
227
+ const zScoreCap = this.settings.hierCluster.zScoreCap;
228
+ return this.hierClusterValues.scale((value - -zScoreCap) / (zScoreCap * 2));
229
+ } else {
230
+ return this.hierClusterValues.scale(value / this.hierClusterValues.max);
231
+ }
232
+ }
233
+ /* returns list of gene terms as request parameter, e.g. {gene,chr,start,stop}
234
+ request parameter only need term but not tw, as it will simply fetch continuous sample values on terms without transform
235
+
236
+ use of this function is unfortunate because:
237
+ the incomplete migration of {name} to {gene} for gene-based term
238
+ geneset edit ui is hardcoded to return {name}
239
+ existing plot states contain {name}
240
+
241
+ !!! migration instruction !!!
242
+ - term.name is for display only, if a term is gene-based, it has term.gene=str
243
+ - a geneVariant term can be based on a genomic range (and not a gene), in that case it won't have term.gene and cannot be used where gene is expected, e.g. gene-based clustering analysis
244
+
245
+ */
246
+ getClusterRowTermsAsParameter() {
247
+ const lst = this.hcTermGroup.lst.map(this.opts.app.vocabApi.getTwMinCopy);
248
+ lst.sort((a, b) => a.term.name < b.term.name ? -1 : 1);
249
+ return lst;
250
+ }
251
+ };
252
+ for (const methods of [hierCluster_renderers_exports, hierCluster_interactivity_exports]) {
253
+ for (const methodName in methods) HierCluster.prototype[methodName] = methods[methodName];
254
+ }
255
+ var hierClusterInit = getCompInit(HierCluster);
256
+ var componentInit = hierClusterInit;
257
+
258
+ export {
259
+ HierCluster,
260
+ hierClusterInit,
261
+ componentInit
262
+ };
263
+ //# sourceMappingURL=chunk-PRPQ654B.js.map