@sjcrh/proteinpaint-client 2.198.0 → 2.200.0

package/dist/chunk-WXPFMVU6.js

@@ -0,0 +1,299 @@
+import {
+  first_genetrack_tolist,
+  gmmode,
+  sayerror
+} from "./chunk-TKW5TW4Z.js";
+import {
+  dofetch3
+} from "./chunk-JVPWIVDT.js";
+import {
+  codon_stop,
+  nt2aa,
+  proteinDomainColorScale
+} from "./chunk-6PNPHACF.js";
+import {
+  select_default
+} from "./chunk-I6Y4O3RR.js";
+
+// common/snp.js
+async function string2snp(genome, str) {
+  const data = await dofetch3("snp", {
+    method: "POST",
+    body: JSON.stringify({ byName: true, genome: genome.name, lst: [str] })
+  });
+  if (data.error) throw data.error;
+  if (!data.results || data.results.length == 0) throw str + ": not a SNP";
+  for (const i of data.results) {
+    const chr = genome.chrlookup[i.chrom.toUpperCase()];
+    if (chr && chr.major) {
+      return {
+        chr: i.chrom,
+        start: i.chromStart,
+        stop: i.chromEnd
+      };
+    }
+  }
+  const r = data.results[0];
+  return {
+    chr: r.chrom,
+    start: r.chromStart,
+    stop: r.chromEnd
+  };
+}
+
+// src/block.init.js
+async function block_init_default(arg) {
+  if (!arg.holder) throw "No holder for block.init";
+  if (!arg.genome) throw "no genome";
+  if (arg.holder instanceof Element) arg.holder = select_default(arg.holder);
+  if (!arg.tklst) arg.tklst = [];
+  if (arg.query) {
+    await step1_findgm(arg);
+    return;
+  }
+  if (arg.model && arg.allmodels) {
+    await step2_getseq(arg);
+    return;
+  }
+}
+async function step1_findgm(arg) {
+  const wait = arg.holder.append("p").style("font-size", "2em").style("color", "#858585").text("Searching for " + arg.query + " ...");
+  const data = await dofetch3("genelookup", {
+    body: { deep: 1, input: arg.query, genome: arg.genome.name }
+  });
+  if (!data) throw "querying genes: server error";
+  if (data.error) throw "error querying genes: " + data.error;
+  if (!data.gmlst || data.gmlst.length == 0) {
+    if (arg.genome.hasSNP) {
+      try {
+        const r = await string2snp(arg.genome, arg.query);
+        wait.remove();
+        const par = {
+          genome: arg.genome,
+          holder: arg.holder,
+          chr: r.chr,
+          start: Math.max(0, r.start - 300),
+          stop: r.start + 300,
+          nobox: true,
+          tklst: arg.tklst,
+          debugmode: arg.debugmode
+        };
+        first_genetrack_tolist(arg.genome, par.tklst);
+        const b = await import("./block-BGSSF6XP.js");
+        const block = new b.Block(par);
+        block.addhlregion(r.chr, r.start, r.stop - 1);
+      } catch (e) {
+        wait.text("Not a gene or SNP: " + arg.query);
+      }
+    } else {
+      wait.text("No match to gene: " + arg.query);
+    }
+    return;
+  }
+  wait.remove();
+  arg.allmodels = data.gmlst;
+  for (const m of arg.allmodels) {
+    if (m.isoform.toUpperCase() == (data.found_isoform ? data.found_isoform.toUpperCase() : arg.query.toUpperCase())) {
+      arg.model = m;
+      await step2_getseq(arg);
+      return;
+    }
+  }
+  const defaultisoforms = [];
+  for (const m of arg.allmodels) {
+    if (!m.isoform) throw "isoform missing from one gene model: " + JSON.stringify(m);
+    const n = m.isoform.toUpperCase();
+    if (arg.genome.isoformcache.has(n)) {
+      let nothas = true;
+      for (const m2 of arg.genome.isoformcache.get(n)) {
+        if (m2.chr == m.chr && m2.start == m.start && m2.stop == m.stop && m2.strand == m.strand) {
+          nothas = false;
+          break;
+        }
+      }
+      if (nothas) {
+        arg.genome.isoformcache.get(n).push(m);
+      }
+    } else {
+      arg.genome.isoformcache.set(n, [m]);
+    }
+    if (m.isoform.toUpperCase() == arg.query.toUpperCase()) {
+      defaultisoforms.push(m);
+      break;
+    }
+    if (m.isdefault) {
+      defaultisoforms.push(m);
+    }
+  }
+  if (defaultisoforms.length == 1) {
+    arg.model = defaultisoforms[0];
+  } else if (defaultisoforms.length > 1) {
+    for (const m of defaultisoforms) {
+      if (m.chr == "chrY") {
+        continue;
+      }
+      const chr = arg.genome.chrlookup[m.chr.toUpperCase()];
+      if (!chr) {
+        continue;
+      }
+      if (!chr.major) {
+        continue;
+      }
+      arg.model = m;
+      break;
+    }
+    if (!arg.model) {
+      arg.model = defaultisoforms[0];
+    }
+  }
+  if (!arg.model) {
+    arg.model = arg.allmodels[0];
+  }
+  await step2_getseq(arg);
+}
+async function step2_getseq(arg) {
+  if (arg.model.genomicseq) {
+    checker();
+    step2_getpdomain(arg);
+    return;
+  }
+  const par = {
+    genome: arg.genome.name,
+    coord: arg.model.chr + ":" + (arg.model.start + 1) + "-" + arg.model.stop
+  };
+  const data = await dofetch3("ntseq", { method: "POST", body: JSON.stringify(par) });
+  if (!data) throw "getting sequence: server error";
+  if (data.error) throw "getting sequence: " + data.error;
+  if (!data.seq) throw "no nt seq???";
+  arg.model.genomicseq = data.seq.toUpperCase();
+  arg.model.aaseq = nt2aa(arg.model);
+  checker();
+  await step2_getpdomain(arg);
+  function checker() {
+    if (arg.model.aaseq) {
+      const stop = arg.model.aaseq.indexOf(codon_stop);
+      const cdslen = arg.model.cdslen - (arg.model.startCodonFrame ? 3 - arg.model.startCodonFrame : 0);
+      if (stop != -1 && stop < cdslen / 3 - 1) {
+        sayerror(arg.holder, "Translating " + arg.model.isoform + " ends at " + stop + " AA, expecting " + cdslen / 3);
+      }
+    }
+  }
+}
+async function step2_getpdomain(arg) {
+  const isoform2gm = /* @__PURE__ */ new Map();
+  for (const m of arg.allmodels) {
+    if (!m.pdomains) {
+      m.pdomains = [];
+      m.domain_hidden = {};
+      if (!isoform2gm.has(m.isoform)) isoform2gm.set(m.isoform, []);
+      isoform2gm.get(m.isoform).push(m);
+    }
+  }
+  if (isoform2gm.size == 0) {
+    await step3(arg);
+    return;
+  }
+  const data = await dofetch3("pdomain", {
+    method: "POST",
+    body: JSON.stringify({ genome: arg.genome.name, isoforms: [...isoform2gm.keys()] })
+  });
+  if (data.error) throw "error getting protein domain: " + data.error;
+  if (!Array.isArray(data.lst)) throw ".lst[] not array";
+  for (const a of data.lst) {
+    for (const m of isoform2gm.get(a.name)) {
+      m.pdomains = a.pdomains;
+      if (arg.hidePdomain) {
+        for (const i of a.pdomains) {
+          m.domain_hidden[i.name + i.description] = 1;
+        }
+      }
+    }
+  }
+  if (arg.geneDomains) {
+    if (typeof arg.geneDomains != "object") throw "geneDomains not object";
+    for (const isoform in arg.geneDomains) {
+      const lst = isoform2gm.get(isoform);
+      if (!lst) throw `unknown isoform ${isoform} from geneDomains{}`;
+      for (const g of lst) {
+        if (!g.pdomains) g.pdomains = [];
+        if (!Array.isArray(arg.geneDomains[isoform])) throw `geneDomains[${isoform}] not array`;
+        for (const b of arg.geneDomains[isoform]) {
+          if (typeof b != "object") throw "element from geneDomains[] not object";
+          if (!Number.isInteger(b.start)) throw "start not integer from geneDomains[]";
+          if (!Number.isInteger(b.stop)) throw "stop not integer from geneDomains[]";
+          if (b.start > b.stop) throw "start>stop from geneDomains[]";
+          if (!b.name) b.name = "Custom domain";
+          if (!g.pdomains.find((a) => a.start == b.start && a.stop == b.stop && a.name == b.name)) g.pdomains.push(b);
+        }
+      }
+    }
+  }
+  const s = proteinDomainColorScale();
+  for (const lst of isoform2gm.values()) {
+    for (const g of lst) {
+      for (const d of g.pdomains || []) {
+        if (!d.color) d.color = s(d.name + d.description);
+      }
+    }
+  }
+  await step3(arg);
+}
+async function step3(arg) {
+  let mode = arg.gmmode;
+  if (!mode) {
+    if (arg.model.cdslen) {
+      mode = gmmode.protein;
+    } else {
+      mode = gmmode.exononly;
+    }
+  }
+  if (arg.dataset) {
+    if (!Array.isArray(arg.dataset)) throw "dataset is not array";
+    for (const dsname of arg.dataset) {
+      if (arg.genome.datasets[dsname] && !arg.genome.datasets[dsname].legacyDsIsUninitiated) continue;
+      const d = await dofetch3(`getDataset?genome=${arg.genome.name}&dsname=${dsname}`);
+      if (d.error) throw `invalid name from dataset[]: ${d.error}`;
+      if (!d.ds) throw ".ds missing";
+      const ds = arg.genome.datasets[d.ds.label];
+      Object.assign(ds, d.ds);
+      const _ = await import("./legacyDataset-4BXYHQTS.js");
+      _.validate_oldds(ds);
+      delete ds.legacyDsIsUninitiated;
+    }
+  }
+  const b = await import("./block-BGSSF6XP.js");
+  arg.__blockInstance = new b.Block({
+    genome: arg.genome,
+    holder: arg.holder,
+    nobox: true,
+    usegm: arg.model,
+    gmstackheight: 37,
+    allgm: arg.allmodels,
+    datasetlst: arg.dataset,
+    legacyDsFilter: arg.legacyDsFilter,
+    mset: arg.mset,
+    hlaachange: arg.hlaachange,
+    hlvariants: arg.hlvariants,
+    hlregions: arg.hlregions,
+    aarange: arg.aarange,
+    gmmode: mode,
+    hidedatasetexpression: arg.hidedatasetexpression,
+    hidegenecontrol: arg.hidegenecontrol,
+    hidegenelegend: arg.hidegenelegend,
+    variantPageCall_snv: arg.variantPageCall_snv,
+    datasetqueries: arg.datasetqueries,
+    samplecart: arg.samplecart,
+    debugmode: arg.debugmode,
+    tklst: arg.tklst,
+    mclassOverride: arg.mclassOverride,
+    hide_dsHandles: arg.hide_dsHandles,
+    onloadalltk_always: arg.onloadalltk_always,
+    onAddRemoveTk: arg.onAddRemoveTk
+  });
+}
+
+export {
+  string2snp,
+  block_init_default
+};
+//# sourceMappingURL=chunk-WXPFMVU6.js.map

package/dist/chunk-XNWUI5VL.js

@@ -0,0 +1,37 @@
+import {
+  addGeneSearchbox,
+  getGEunit
+} from "./chunk-TKW5TW4Z.js";
+import {
+  Menu
+} from "./chunk-HYOEWQ5P.js";
+import {
+  TermTypes
+} from "./chunk-6PNPHACF.js";
+
+// termdb/handlers/geneExpression.ts
+var SearchHandler = class {
+  init(opts) {
+    this.callback = opts.callback;
+    this.app = opts.app;
+    const holder = opts.holder.append("div").style("padding", "10px 0px");
+    const geneSearch = addGeneSearchbox({
+      tip: new Menu({ padding: "0px" }),
+      genome: opts.genomeObj,
+      row: holder,
+      searchOnly: "gene",
+      callback: () => this.selectGene(geneSearch.geneSymbol)
+    });
+  }
+  async selectGene(gene) {
+    const unit = getGEunit(this.app.vocabApi);
+    const name = `${gene} ${unit}`;
+    if (!gene) throw new Error("No gene selected");
+    this.callback({ gene, name, type: TermTypes.GENE_EXPRESSION });
+  }
+};
+
+export {
+  SearchHandler
+};
+//# sourceMappingURL=chunk-XNWUI5VL.js.map

package/dist/chunk-XNWUI5VL.js.map

@@ -0,0 +1,7 @@
+{
+  "version": 3,
+  "sources": ["../termdb/handlers/geneExpression.ts"],
+  "sourcesContent": ["import { Menu, addGeneSearchbox } from '#dom'\nimport { TermTypes } from '#types'\nimport { getGEunit } from '#tw/geneExpression'\n\nexport class SearchHandler {\n\tcallback: any\n\tapp: any\n\tinit(opts) {\n\t\tthis.callback = opts.callback\n\t\tthis.app = opts.app\n\t\tconst holder = opts.holder.append('div').style('padding', '10px 0px')\n\t\tconst geneSearch = addGeneSearchbox({\n\t\t\ttip: new Menu({ padding: '0px' }),\n\t\t\tgenome: opts.genomeObj,\n\t\t\trow: holder,\n\t\t\tsearchOnly: 'gene',\n\t\t\tcallback: () => this.selectGene(geneSearch.geneSymbol)\n\t\t})\n\t}\n\n\tasync selectGene(gene) {\n\t\tconst unit = getGEunit(this.app.vocabApi)\n\t\tconst name = `${gene} ${unit}`\n\t\tif (!gene) throw new Error('No gene selected')\n\t\tthis.callback({ gene, name, type: TermTypes.GENE_EXPRESSION })\n\t}\n}\n"],
+  "mappings": ";;;;;;;;;;;;AAIO,IAAM,gBAAN,MAAoB;AAAA,EAG1B,KAAK,MAAM;AACV,SAAK,WAAW,KAAK;AACrB,SAAK,MAAM,KAAK;AAChB,UAAM,SAAS,KAAK,OAAO,OAAO,KAAK,EAAE,MAAM,WAAW,UAAU;AACpE,UAAM,aAAa,iBAAiB;AAAA,MACnC,KAAK,IAAI,KAAK,EAAE,SAAS,MAAM,CAAC;AAAA,MAChC,QAAQ,KAAK;AAAA,MACb,KAAK;AAAA,MACL,YAAY;AAAA,MACZ,UAAU,MAAM,KAAK,WAAW,WAAW,UAAU;AAAA,IACtD,CAAC;AAAA,EACF;AAAA,EAEA,MAAM,WAAW,MAAM;AACtB,UAAM,OAAO,UAAU,KAAK,IAAI,QAAQ;AACxC,UAAM,OAAO,GAAG,IAAI,IAAI,IAAI;AAC5B,QAAI,CAAC,KAAM,OAAM,IAAI,MAAM,kBAAkB;AAC7C,SAAK,SAAS,EAAE,MAAM,MAAM,MAAM,UAAU,gBAAgB,CAAC;AAAA,EAC9D;AACD;",
+  "names": []
+}

package/dist/chunk-YBLTSYQV.js

@@ -0,0 +1,216 @@
+import {
+  make_radios
+} from "./chunk-TKW5TW4Z.js";
+import {
+  initBinConfig
+} from "./chunk-JVPWIVDT.js";
+import {
+  format
+} from "./chunk-UJELJXJG.js";
+
+// termsetting/handlers/NumRegularBinEditor.ts
+var NumRegularBinEditor = class {
+  constructor(editHandler) {
+    this.dom = {};
+    this.editHandler = editHandler;
+    this.opts = editHandler.opts;
+    this.tw = editHandler.tw;
+    this.termsetting = editHandler.termsetting;
+  }
+  render(div) {
+    this.tw = this.editHandler.tw;
+    this.q = this.getDefaultQ();
+    this.editHandler.handler.density.setBinLines(this.getBoundaryOpts());
+    if (this.dom.binsTable) {
+      if (this.editHandler.dom.binsDiv?.node().contains(this.dom.binsTable.node())) return;
+      else {
+        this.dom.binsTable.remove();
+        delete this.dom.binsTable;
+      }
+    }
+    const binsTable = div.append("table");
+    this.dom.binsTable = binsTable;
+    this.renderBinSizeInput(binsTable.append("tr"));
+    this.renderFirstBinInput(binsTable.append("tr"));
+    this.renderLastBinInputs(binsTable.append("tr"));
+  }
+  getDefaultQ() {
+    if (this.tw.q.type == "regular-bin") return JSON.parse(JSON.stringify(this.tw.q));
+    const t = this.tw.term;
+    const defaultQ = this.termsetting.opts.use_bins_less && t.bins?.less || t.bins?.default;
+    if (defaultQ) return JSON.parse(JSON.stringify(defaultQ));
+    const binConfig = initBinConfig(this.editHandler.handler.density_data);
+    return typeof binConfig == "string" ? JSON.parse(binConfig) : binConfig;
+  }
+  renderBinSizeInput(tr) {
+    const handler = this.editHandler.handler;
+    tr.append("td").style("margin", "5px").style("opacity", 0.5).text("Bin Size");
+    const { min, max } = handler.density_data;
+    const q = this.q;
+    const origBinSize = q.bin_size;
+    this.dom.bin_size_input = tr.append("td").append("input").attr("type", "number").attr("value", "rounding" in q ? format(q.rounding || ".0f")(q.bin_size) : q.bin_size).attr("data-testid", "sjpp-num-reg-bin-editor-size").style("margin-left", "15px").style("width", "100px").style("color", () => q.bin_size > Math.abs(max - min) ? "red" : "").on("change", (event) => {
+      const newValue = Number(event.target.value);
+      if (newValue <= 0) {
+        window.alert("Please enter non-negative bin size.");
+        event.target.value = origBinSize;
+        return;
+      }
+      if ((max - min) / newValue > 100) {
+        window.alert("Bin size too small. Try setting a bigger value.");
+        event.target.value = origBinSize;
+        return;
+      }
+      q.bin_size = newValue;
+      this.dom.bin_size_input.style("color", q.bin_size > max - min ? "red" : newValue != origBinSize ? "green" : "");
+      handler.density.setBinLines(this.getBoundaryOpts());
+    });
+  }
+  renderFirstBinInput(tr) {
+    const handler = this.editHandler.handler;
+    const q = this.q;
+    if (!q.first_bin) throw "missing q.first_bin";
+    tr.append("td").style("margin", "5px").style("opacity", 0.5).text("First Bin Stop");
+    const { min, max } = handler.density_data;
+    const origValue = q.first_bin.stop;
+    this.dom.first_stop_input = tr.append("td").append("input").attr("type", "number").property("value", origValue).style("width", "100px").style("margin-left", "15px").on("change", (event) => {
+      const newValue = Number(event.target.value);
+      if (newValue < min || newValue > max) {
+        window.alert("First bin stop value out of bound.");
+        event.target.value = origValue;
+        return;
+      }
+      this.q.first_bin.stop = newValue;
+      handler.density.setBinLines(this.getBoundaryOpts());
+    });
+    tr.append("td").append("div").style("font-size", ".6em").style("opacity", 0.5).style("display", handler.density.no_density_data ? "none" : "block").text("Indicated by left-most red line. Drag to change.");
+  }
+  renderLastBinInputs(tr) {
+    const handler = this.editHandler.handler;
+    const q = this.q;
+    const isAuto = !q.last_bin || !Number.isFinite(q.last_bin.start);
+    tr.append("td").style("padding-top", "4px").style("opacity", 0.5).style("vertical-align", "top").text("Last Bin Start");
+    const td1 = tr.append("td").style("padding-left", "15px").style("vertical-align", "top");
+    const radio_div = td1.append("div");
+    const radios = make_radios({
+      holder: radio_div,
+      options: [
+        { label: "Automatic", value: "auto", checked: isAuto },
+        { label: "Fixed", value: "fixed", checked: !isAuto }
+      ],
+      callback: (v) => {
+        if (v == "auto") {
+          delete q.last_bin;
+          edit_div.style("display", "none");
+          handler.density.setBinLines(this.getBoundaryOpts());
+          return;
+        }
+        edit_div.style("display", "inline-block");
+        if (this.dom.last_start_input.property("value") == "") {
+          this.dom.last_start_input.property("value", this.tw.q.last_bin?.start || handler.density_data.max);
+        }
+        this.setLastBinStart();
+      }
+    });
+    this.dom.fixed_radio = radios.inputs.filter((_, i) => i === 1);
+    const edit_div = tr.append("td").append("div").style("display", isAuto ? "none" : "inline-block");
+    this.dom.last_start_input = edit_div.append("input").attr("type", "number").property("value", q.last_bin?.start || "").style("width", "100px").on("change", () => this.setLastBinStart());
+    edit_div.append("div").style("font-size", ".6em").style("opacity", 0.5).style("display", handler.density.no_density_data ? "none" : "block").text("Indicated by right-most red line. Drag to change.");
+  }
+  setLastBinStart() {
+    const q = this.q;
+    const { max } = this.editHandler.handler.density_data;
+    const strInput = this.dom.last_start_input.property("value");
+    if (strInput === "") return;
+    const inputValue = Number(strInput);
+    if (q.first_bin && inputValue <= q.first_bin.stop) {
+      window.alert("Last bin start cannot be smaller than first bin stop.");
+      this.dom.last_start_input.property("value", max);
+      return;
+    }
+    if (inputValue > max) {
+      window.alert("Last bin start value out of bound.");
+      this.dom.last_start_input.property("value", max);
+      return;
+    }
+    if (q.last_bin) q.last_bin.start = inputValue;
+    else
+      q.last_bin = {
+        start: inputValue,
+        stopunbounded: true,
+        stopinclusive: false
+      };
+    this.editHandler.handler.density.setBinLines(this.getBoundaryOpts());
+  }
+  getBoundaryOpts() {
+    const { min, max } = this.editHandler.handler.density_data;
+    const binLinesStop = this.q.last_bin?.start ?? max + Math.abs(this.q.first_bin.stop) - Math.min(min, 0);
+    const boundaryValues = [];
+    for (let i = this.q.first_bin.stop; i <= binLinesStop; i = i + this.q.bin_size) {
+      if (this.q.last_bin?.start === i) break;
+      if (i > binLinesStop) boundaryValues[boundaryValues.length - 1].isLastVisibleLine = true;
+      const isDraggable = i === this.q.first_bin.stop || i === this.q.bin_size - 1;
+      boundaryValues.push({ x: i, isDraggable, movesWithLineIndex: !isDraggable ? 0 : -1 });
+    }
+    if (this.q.last_bin) {
+      boundaryValues.push({
+        x: this.q.last_bin.start,
+        isDraggable: true,
+        isLastVisibleLine: true,
+        movesWithLineIndex: -1
+      });
+    }
+    return {
+      values: boundaryValues,
+      callback: (d, value) => {
+        if (d.index === 0) {
+          this.dom.first_stop_input.property("value", value);
+          this.q.first_bin.stop = value;
+        } else {
+          this.editHandler.handler.dom.last_start_input.property("value", value);
+          if (this.q.last_bin) this.q.last_bin.start = value;
+        }
+      }
+    };
+  }
+  getEditedQ(destroyDom = true) {
+    const bin_size = this.dom.bin_size_input.property("value");
+    const config = {
+      mode: "discrete",
+      type: "regular-bin",
+      startinclusive: this.editHandler.boundaryInclusion == "startinclusive",
+      stopinclusive: this.editHandler.boundaryInclusion == "stopinclusive",
+      bin_size: Number(bin_size),
+      first_bin: {
+        startunbounded: true,
+        stop: Number(this.dom.first_stop_input.property("value"))
+      },
+      rounding: bin_size.includes(".") && !bin_size.endsWith(".") ? `.${bin_size.split(".")[1].length}f` : ".0f"
+    };
+    if (this.dom.fixed_radio.property("checked")) {
+      config.last_bin = {
+        start: Number(this.dom.last_start_input.property("value")),
+        stopunbounded: true
+      };
+    }
+    if (destroyDom) {
+      for (const name of Object.keys(this.dom)) {
+        this.dom[name].remove();
+        delete this.dom[name];
+      }
+    }
+    return config;
+  }
+  undoEdits() {
+    this.q = this.getDefaultQ();
+    this.dom.binsTable.selectAll("*").remove();
+    this.renderBinSizeInput(this.dom.binsTable.append("tr"));
+    this.renderFirstBinInput(this.dom.binsTable.append("tr"));
+    this.renderLastBinInputs(this.dom.binsTable.append("tr"));
+    this.editHandler.handler.density.setBinLines(this.getBoundaryOpts());
+  }
+};
+
+export {
+  NumRegularBinEditor
+};
+//# sourceMappingURL=chunk-YBLTSYQV.js.map

package/dist/chunk-Z7VDFWIP.js

@@ -0,0 +1,126 @@
+import {
+  formatRangeBounds
+} from "./chunk-BZTWTH4Y.js";
+import {
+  roundValueAuto
+} from "./chunk-TLT4YIG3.js";
+import {
+  brushX
+} from "./chunk-5R63Q5KH.js";
+import {
+  select_default
+} from "./chunk-I6Y4O3RR.js";
+
+// filter/tvs.density.js
+function addBrushes(self, new_brush_location) {
+  const brushes = self.num_obj.brushes;
+  const maxvalue = self.num_obj.density_data.max;
+  const minvalue = self.num_obj.density_data.min;
+  const rawDecile = (maxvalue - minvalue) / 10;
+  const decile = self.tvs.term.type == "integer" ? Math.floor(rawDecile) : rawDecile;
+  for (const [i, r] of self.num_obj.ranges.entries()) {
+    const _b = brushes.find((b) => b.orig === r);
+    let brush;
+    if (!_b) {
+      brush = { orig: r, range: JSON.parse(JSON.stringify(r)) };
+      brushes.push(brush);
+    } else {
+      brush = _b;
+    }
+    if (r.start === "") {
+      if (new_brush_location == "center") brush.range.start = minvalue + decile * 4;
+      else brush.range.start = minvalue + decile * 8;
+    }
+    if (r.stop === "") {
+      if (new_brush_location == "center") brush.range.stop = minvalue + decile * 6;
+      else brush.range.stop = Math.floor(maxvalue);
+    }
+  }
+  const range_brushes = self.num_obj.brush_g.selectAll(".range_brush").data(brushes, (d) => brushes.indexOf(d));
+  range_brushes.exit().remove();
+  range_brushes.each(function(d, i) {
+    select_default(this).selectAll(".overlay").style("pointer-events", "all");
+  });
+  range_brushes.enter().append("g").attr("class", "range_brush").each(function(brush, i) {
+    applyBrush(self, this, brush, i);
+  });
+}
+function applyBrush(self, elem, brush) {
+  if (!brush.elem) brush.elem = select_default(elem);
+  const range = brush.range;
+  const plot_size = self.num_obj.plot_size;
+  const xscale = self.num_obj.xscale;
+  const maxvalue = self.num_obj.density_data.max;
+  const minvalue = self.num_obj.density_data.min;
+  brush.d3brush = brushX().extent([
+    [0, 0],
+    [plot_size.width, plot_size.height]
+  ]).on("brush", function(event, d) {
+    const s = event.selection;
+    if (!s) return;
+    const inputRange = brush.rangeInput.getRange();
+    if (inputRange?.value != void 0) {
+      brush.range = inputRange;
+      return;
+    }
+    updateTempRanges(xscale, s, range, inputRange, minvalue, maxvalue, self.tvs.term.type);
+    const [start, stop] = setStartStopDisplays(range, inputRange);
+    brush.rangeInput.getInput().node().value = `${start} x ${stop}`;
+  }).on("end", function() {
+    brush.elem.selectAll(".overlay").style("pointer-events", "none");
+  });
+  const brush_start = range.startunbounded ? minvalue : range.start;
+  const brush_stop = range.stopunbounded ? maxvalue : range.stop;
+  brush.init = () => {
+    if (range.value == void 0)
+      brush.elem.call(brush.d3brush).call(brush.d3brush.move, [brush_start, brush_stop].map(xscale));
+  };
+  if (range.startunbounded) delete range.start;
+  if (range.stopunbounded) delete range.stop;
+  brush.elem.selectAll(".selection").style(
+    "fill",
+    brush.orig.start === "" && brush.orig.stop === "" || JSON.stringify(range) != JSON.stringify(brush.orig) ? "#23cba7" : "#777777"
+  );
+}
+function updateTempRanges(xscale, s, range, inputRange, minvalue, maxvalue, type) {
+  range.start = convertRangeValue(xscale, s[0]);
+  range.stop = convertRangeValue(xscale, s[1]);
+  const min = roundValueAuto(Number(minvalue));
+  const max = roundValueAuto(Number(maxvalue));
+  if (range.start < min) range.start = min;
+  if (range.stop > max) range.stop = max;
+  range.startunbounded = min == range.start && inputRange.startunbounded;
+  range.stopunbounded = max == range.stop && inputRange.stopunbounded;
+  if (type == "integer") {
+    range.start = range.startunbounded ? "" : Math.round(range.start);
+    range.stop = range.stopunbounded ? "" : Math.round(range.stop);
+  }
+}
+function setStartStopDisplays(range, inputRange) {
+  return formatRangeBounds({
+    ...range,
+    startinclusive: inputRange.startinclusive,
+    stopinclusive: inputRange.stopinclusive
+  });
+}
+function convertRangeValue(xscale, sidx) {
+  const value = Number(xscale.invert(sidx));
+  return roundValueAuto(value);
+}
+function addNewBrush(self, new_brush_location = "end", callback) {
+  const new_range = { start: "", stop: "", index: self.tvs.ranges.length };
+  self.num_obj.ranges.push(new_range);
+  const brush = { orig: new_range, range: JSON.parse(JSON.stringify(new_range)) };
+  self.num_obj.brushes.push(brush);
+  addBrushes(self, new_brush_location);
+  if (callback) callback();
+  brush.init();
+}
+
+export {
+  addBrushes,
+  updateTempRanges,
+  setStartStopDisplays,
+  addNewBrush
+};
+//# sourceMappingURL=chunk-Z7VDFWIP.js.map