@sjcrh/proteinpaint-client 2.182.0 → 2.182.1
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/dist/2dmaf-YHYYSSKR.js +1371 -0
- package/dist/AIProjectAdmin-D4AASQBM.js +830 -0
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- package/dist/DEinput-KVILE7QQ.js +297 -0
- package/dist/DifferentialAnalysis-P6GKHAS5.js +238 -0
- package/dist/Disco-IMLXEBPG.js +3235 -0
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- package/dist/NumRegularBinEditor-OYELFDIB.js +36 -0
- package/dist/NumRegularBinEditor.unit.spec-44SALKLH.js +225 -0
- package/dist/NumSplineEditor-SENQC4P2.js +190 -0
- package/dist/NumSplineEditor.unit.spec-XKB4XXU4.js +197 -0
- package/dist/NumericDensity-GCNWO7YS.js +36 -0
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- package/dist/barchart.events-MQNQTSWI.js +45 -0
- package/dist/barchart.integration.spec-DSO2377T.js +1675 -0
- package/dist/bars.renderer-S7A7I6BQ.js +12 -0
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- package/dist/block.mds.expressionrank-643H7PN7.js +357 -0
- package/dist/block.mds.geneboxplot-C222ODSL.js +826 -0
- package/dist/block.mds.junction-C5DJRUOK.js +1543 -0
- package/dist/block.mds.svcnv-4G74JQ7Y.js +6799 -0
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- package/dist/block.tk.pgv-HETJVWXH.js +942 -0
- package/dist/brainImaging-K3LHK3DD.js +421 -0
- package/dist/chat-BYX5ARUK.js +148 -0
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import {
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isDictionaryType
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} from "./chunk-6ITDJ5UR.js";
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import {
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dtcnv,
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dtfusionrna,
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dtsnvindel,
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mclasscnvAmp,
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mclasscnvHomozygousDel,
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mclasscnvgain,
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mclasscnvloh,
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mclasscnvloss
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} from "./chunk-XYFDBYOY.js";
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// plots/matrix/matrix.sort.js
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function getSampleSorter(self, settings, rows, opts = {}) {
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const s = settings;
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validateSettings(s);
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if (self.config.chartType == "hierCluster" && self.config.settings.hierCluster.clusterSamples) {
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return self.hcSampleSorter;
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}
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if (s.sortSamplesBy == "asListed") {
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return (a, b) => {
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return self.asListedSampleOrder.indexOf(a.sample) - self.asListedSampleOrder.indexOf(b.sample);
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};
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}
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if (s.sortSamplesBy == "name") {
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return sortSamplesByName;
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}
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const activeOption = s.sortOptions[s.sortSamplesBy];
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if (!activeOption) throw `unsupported s.sortSamplesBy='${s.sortSamplesBy}'`;
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self.selectedTermsToSortAgainst = self.termOrder.filter((t) => t.tw.sortSamples);
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const selectedTerms = self.selectedTermsToSortAgainst.map((t) => t.tw).sort((a, b) => a.sortSamples.priority - b.sortSamples.priority);
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const sorterTerms = [];
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const sortPriority = activeOption.sortPriority;
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if (sortPriority) {
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for (const _tw of selectedTerms) {
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const tw = structuredClone(_tw);
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if (tw.sortSamples?.by) {
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sorterTerms.push(Object.assign({}, tw));
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continue;
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}
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for (const p of sortPriority) {
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if (opts.skipSorter?.(p, tw)) continue;
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const type = tw.term.type == "geneVariant" && tw.q.type != "values" ? "categorical" : tw.term.type;
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if (!p.types.includes(type)) continue;
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for (const tb of p.tiebreakers) {
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const sortSamples = Object.assign(structuredClone(tw.sortSamples || {}), tb);
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const sorter = Object.assign(structuredClone(tw), { sortSamples });
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sorterTerms.push(sorter);
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}
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}
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}
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}
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if (sortPriority) {
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for (const p of sortPriority) {
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for (const t of self.termOrder) {
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if (selectedTerms.find((tw) => tw.$id === t.tw.$id)) continue;
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if (opts.skipSorter?.(p, t.tw)) continue;
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if (!p.types.includes(t.tw.term.type)) continue;
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for (const tb of p.tiebreakers) {
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sorterTerms.push(Object.assign({}, t.tw, { sortSamples: tb }));
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}
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}
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}
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} else {
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const unSelectedDictTerms = self.app.vocabApi.vocab?.dslabel == "PNET" ? [] : self.termOrder.filter(
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(t) => !t.tw.sortSamples && isDictionaryType(t.tw.term.type) && !selectedTerms.find((tw) => tw.$id === t.tw.$id)
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).map((t) => Object.assign({ sortSamples: { by: "values" } }, t.tw));
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const unSelectedNonDictTerms = self.app.vocabApi.vocab?.dslabel == "PNET" ? [] : self.termOrder.filter(
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(t) => !t.tw.sortSamples && !isDictionaryType(t.tw.term.type) && !selectedTerms.find((tw) => tw.$id === t.tw.$id)
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).map((t) => Object.assign({ sortSamples: { by: "hits" } }, t.tw));
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sorterTerms.push(...unSelectedNonDictTerms, ...unSelectedDictTerms);
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}
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if (opts.tiebreaker) sorterTerms.push(opts.tiebreaker);
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sorterTerms.push(...s.sortSamplesTieBreakers.map((st) => st));
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const sampleSorters = [];
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self.maxSampleSet = /* @__PURE__ */ new Set();
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for (const st of sorterTerms) {
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if (typeof st === "function") sampleSorters.push(st);
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else if (st.$id == "sample") sampleSorters.push(sortSamplesByName);
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else if (st.sortSamples.by == "hits") sampleSorters.push(getSortSamplesByHits(st, self, rows, s));
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else if (st.term.type != "geneVariant") sampleSorters.push(getSortSamplesByValues(st, self, rows, s));
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else if (st.sortSamples.by == "values") sampleSorters.push(getSortSamplesByValues(st, self, rows, s));
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else if (st.sortSamples.by == "dt") sampleSorters.push(getSortSamplesByDt(st, self, rows, s));
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else if (st.sortSamples.by == "class") sampleSorters.push(getSortSamplesByClass(st, self, rows, s));
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else throw `unsupported sortSamplesBy entry by='${st.sortSamples.by}'`;
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}
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if (!sampleSorters.find((f) => f.$id === "sample")) {
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sampleSorters.push(sortSamplesByName);
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}
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return (a, b) => {
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for (const sorter of sampleSorters) {
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const i = sorter(a, b);
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if (i !== 0) return i;
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}
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};
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}
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function validateSettings(s) {
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if (!s.sortOptions) s.sortOptions = "custom";
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if (["selectedTerms", "class", "dt", "hits"].includes(s.sortSamplesBy)) s.sortSamplesBy = "custom";
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}
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function sortSamplesByName(a, b) {
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if (a._ref_.label && b._ref_.label) {
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return a._ref_.label < b._ref_.label ? -1 : a._ref_.label > b._ref_.label ? 1 : 0;
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}
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if (!a.sample && !b.sample && a.row.sample) {
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return a.row.sample < b.row.sample ? -1 : a.row.sample > b.row.sample ? 1 : 0;
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}
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return a.sample < b.sample ? -1 : a.sample > b.sample ? 1 : 0;
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}
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112
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function getSortSamplesByHits(st, self, rows, s) {
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const { $id, sortSamples } = st;
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const hits = {};
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for (const row of rows) {
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if (!hits[row.sample]) hits[row.sample] = 0;
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if ($id in row) {
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hits[row.sample] += row[$id].countedValues?.length || 0;
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}
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}
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return (a, b) => hits[a.sample] == hits[b.sample] ? 0 : hits[a.sample] > hits[b.sample] ? -1 : 1;
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}
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123
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function getSortSamplesByValues(st, self, rows, s) {
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const { $id, sortSamples } = st;
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const t = self.termOrder.find((t2) => t2.tw.$id === $id);
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if (t.grp.type == "hierCluster") {
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return (a, b) => {
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if ($id in a && $id in b) {
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return a[$id]?.values[0].value - b[$id]?.values[0].value;
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}
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if ($id in a) return -1;
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if ($id in b) return 1;
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return 0;
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};
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}
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if (t.tw.term.type == "termCollection") {
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return (a, b) => {
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if ($id in a && $id in b) {
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return a[$id]?.numerators_sum - b[$id]?.numerators_sum;
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}
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141
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if ($id in a) return -1;
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if ($id in b) return 1;
|
|
143
|
+
return 0;
|
|
144
|
+
};
|
|
145
|
+
}
|
|
146
|
+
if (t.tw.q?.mode == "continuous") {
|
|
147
|
+
return (a, b) => {
|
|
148
|
+
if ($id in a && $id in b) {
|
|
149
|
+
return a[$id]?.value - b[$id]?.value;
|
|
150
|
+
}
|
|
151
|
+
if ($id in a) return -1;
|
|
152
|
+
if ($id in b) return 1;
|
|
153
|
+
return 0;
|
|
154
|
+
};
|
|
155
|
+
}
|
|
156
|
+
const values = [];
|
|
157
|
+
if (t?.term?.values) {
|
|
158
|
+
for (const v of term.values) {
|
|
159
|
+
values.push(v.key);
|
|
160
|
+
}
|
|
161
|
+
values.sort((a, b) => term.values[a].order < term.values[a].order ? -1 : 1);
|
|
162
|
+
} else if (t?.ref?.bins) {
|
|
163
|
+
values.push(...t.ref.bins.map((b) => b.name));
|
|
164
|
+
} else if (t.tw.q?.type == "predefined-groupset" || t.tw.q?.type == "custom-groupset") {
|
|
165
|
+
const groupset = t.tw.q.type == "predefined-groupset" ? t.tw.term.groupsetting.lst[t.tw.q.predefined_groupset_idx] : t.tw.q.customset;
|
|
166
|
+
if (!groupset) throw "groupset missing";
|
|
167
|
+
const grpNames = groupset.groups.filter((group) => !group.uncomputable).map((group) => group.name);
|
|
168
|
+
values.push(...grpNames);
|
|
169
|
+
} else {
|
|
170
|
+
for (const row of rows) {
|
|
171
|
+
if (!($id in row)) continue;
|
|
172
|
+
const v = row[$id].override?.key || row[$id].key;
|
|
173
|
+
if (values.indexOf(v) == -1) values.push(v);
|
|
174
|
+
}
|
|
175
|
+
}
|
|
176
|
+
return (a, b) => {
|
|
177
|
+
if (!a[$id] && !b[$id]) return 0;
|
|
178
|
+
if (!a[$id]) return b[$id].override ? -1 : 1;
|
|
179
|
+
if (!b[$id]) return a[$id].override ? 1 : -1;
|
|
180
|
+
if (a[$id].override && b[$id].override) {
|
|
181
|
+
const ak = "order" in a[$id].override ? a[$id].override.order : values.indexOf(a[$id].override.key);
|
|
182
|
+
const bk = "order" in b[$id].override ? b[$id].override.order : values.indexOf(b[$id].override.key);
|
|
183
|
+
return ak - bk;
|
|
184
|
+
}
|
|
185
|
+
if (!a[$id].override && !b[$id].override) {
|
|
186
|
+
return values.indexOf(a[$id].key) - values.indexOf(b[$id].key);
|
|
187
|
+
}
|
|
188
|
+
if (!a[$id].override) return -1;
|
|
189
|
+
if (!b[$id].override) return 1;
|
|
190
|
+
return 0;
|
|
191
|
+
};
|
|
192
|
+
}
|
|
193
|
+
function getSortSamplesByDt(st, self, rows, s) {
|
|
194
|
+
const { $id, sortSamples, term: term2 } = st;
|
|
195
|
+
const order = sortSamples.order;
|
|
196
|
+
const nextRound = order.length + 1;
|
|
197
|
+
const dt = /* @__PURE__ */ new Map();
|
|
198
|
+
function setSortIndex(row) {
|
|
199
|
+
if (!($id in row)) {
|
|
200
|
+
dt.set(row.sample, nextRound);
|
|
201
|
+
return;
|
|
202
|
+
}
|
|
203
|
+
if (sortSamples.filter && !findMatchingValue(row[$id].values, sortSamples.filter.values)) {
|
|
204
|
+
dt.set(row.sample, nextRound);
|
|
205
|
+
return;
|
|
206
|
+
}
|
|
207
|
+
const indices = row[$id].values.map((v) => order.indexOf(v.dt)).filter((i) => i !== -1);
|
|
208
|
+
dt.set(row.sample, indices.length ? Math.min(...indices) : nextRound);
|
|
209
|
+
}
|
|
210
|
+
return (a, b) => {
|
|
211
|
+
if (!dt.has(a.sample)) setSortIndex(a);
|
|
212
|
+
if (!dt.has(b.sample)) setSortIndex(b);
|
|
213
|
+
return dt.get(a.sample) - dt.get(b.sample);
|
|
214
|
+
};
|
|
215
|
+
}
|
|
216
|
+
function getSortSamplesByClass(st, self, rows, s) {
|
|
217
|
+
const { $id, sortSamples } = st;
|
|
218
|
+
if (sortSamples.disabled) return () => 0;
|
|
219
|
+
const m = self.config.settings.matrix;
|
|
220
|
+
const includeSSM = m.showMatrixMutation != "none" && !m.allMatrixMutationHidden;
|
|
221
|
+
const includeCNV = m.showMatrixCNV != "none" && !m.allMatrixCNVHidden;
|
|
222
|
+
const order = sortSamples.order.filter(
|
|
223
|
+
includeSSM && includeCNV ? (v) => !m.hiddenVariants.includes(v) : !includeSSM && !includeCNV ? () => false : includeSSM ? (v) => m.mutationClasses.includes(v) && !m.hiddenVariants.includes(v) : includeCNV ? (v) => v.startsWith("CNV_") && !m.hiddenVariants.includes(v) : (v) => !v.startsWith("CNV_")
|
|
224
|
+
);
|
|
225
|
+
if (!order.length && sortSamples.ignoreEmptyFilteredOrder) return () => 0;
|
|
226
|
+
const nextRound = "z";
|
|
227
|
+
const cls = /* @__PURE__ */ new Map();
|
|
228
|
+
function setSortIndex(row) {
|
|
229
|
+
if (!($id in row)) {
|
|
230
|
+
cls.set(row.sample, nextRound);
|
|
231
|
+
return;
|
|
232
|
+
}
|
|
233
|
+
const values = row[$id].renderedValues || row[$id].filteredValues || row[$id].values;
|
|
234
|
+
if (sortSamples.filter && !findMatchingValue(values, sortSamples.filter.values)) {
|
|
235
|
+
cls.set(row.sample, nextRound);
|
|
236
|
+
return;
|
|
237
|
+
}
|
|
238
|
+
const vals = values.map((v) => v.class);
|
|
239
|
+
if (!order.find((mcls) => vals.includes(mcls))) {
|
|
240
|
+
cls.set(row.sample, nextRound);
|
|
241
|
+
return;
|
|
242
|
+
} else if (!sortSamples.isOrdered) {
|
|
243
|
+
cls.set(row.sample, "1");
|
|
244
|
+
} else {
|
|
245
|
+
const str = order.map((mcls) => vals.includes(mcls) ? "1" : "x");
|
|
246
|
+
cls.set(row.sample, str);
|
|
247
|
+
}
|
|
248
|
+
}
|
|
249
|
+
return (a, b) => {
|
|
250
|
+
if (!cls.has(a.sample)) setSortIndex(a);
|
|
251
|
+
if (!cls.has(b.sample)) setSortIndex(b);
|
|
252
|
+
const ca = cls.get(a.sample);
|
|
253
|
+
const cb = cls.get(b.sample);
|
|
254
|
+
return ca < cb ? -1 : ca > cb ? 1 : 0;
|
|
255
|
+
};
|
|
256
|
+
}
|
|
257
|
+
function findMatchingValue(annoValues, filterValues) {
|
|
258
|
+
for (const v of annoValues) {
|
|
259
|
+
for (const f of filterValues) {
|
|
260
|
+
if ((!f.dt || v.dt === f.dt) && (!f.mclassLst || f.mclassLst.includes(v.class)) && (!f.class || f.class === v.class) && (!f.origin || v.origin === f.origin)) {
|
|
261
|
+
return true;
|
|
262
|
+
}
|
|
263
|
+
}
|
|
264
|
+
}
|
|
265
|
+
}
|
|
266
|
+
function getTermSorter(self, s, grp) {
|
|
267
|
+
if (grp?.type == "hierCluster") return self.hcTermSorter;
|
|
268
|
+
if (s.sortTermsBy == "asListed") {
|
|
269
|
+
return (a, b) => a.index - b.index;
|
|
270
|
+
}
|
|
271
|
+
if (s.sortTermsBy != "sampleCount") {
|
|
272
|
+
throw `unsupported s.sortTermsBy='${s.sortTermsBy}'`;
|
|
273
|
+
}
|
|
274
|
+
return (a, b) => {
|
|
275
|
+
if (self.app.vocabApi.vocab?.dslabel === "GDC") {
|
|
276
|
+
if (a.tw?.term?.id && !b.tw?.term?.id) return -1;
|
|
277
|
+
if (!a.tw?.term?.id && b.tw?.term?.id) return 1;
|
|
278
|
+
}
|
|
279
|
+
if (b.counts.samples !== a.counts.samples) return b.counts.samples - a.counts.samples;
|
|
280
|
+
if (b.counts.hits !== a.counts.hits) return b.counts.hits - a.counts.hits;
|
|
281
|
+
return a.index - b.index;
|
|
282
|
+
};
|
|
283
|
+
}
|
|
284
|
+
function getSortOptions(termdbConfig, controlLabels = {}, matrixSettings) {
|
|
285
|
+
const s = matrixSettings || termdbConfig?.matrix?.settings || {};
|
|
286
|
+
const l = Object.assign({ sample: "sample" }, controlLabels, s.controlLabels || {});
|
|
287
|
+
const sortOptions = {};
|
|
288
|
+
if (s.sortPriority) {
|
|
289
|
+
const order = 1;
|
|
290
|
+
Object.values(sortOptions).forEach((d) => {
|
|
291
|
+
if (d.order >= order) d.order += 1;
|
|
292
|
+
});
|
|
293
|
+
sortOptions.custom = {
|
|
294
|
+
label: s.sortPriority.label || "Custom sort",
|
|
295
|
+
value: "custom",
|
|
296
|
+
order,
|
|
297
|
+
sortPriority: s.sortPriority
|
|
298
|
+
};
|
|
299
|
+
}
|
|
300
|
+
sortOptions.a = s.sortOptions?.a ? reshapeSortPriority(s.sortOptions.a, l) : {
|
|
301
|
+
//label: l.Mutation + ' categories', //'CNV+SSM > SSM-only > CNV-only',
|
|
302
|
+
// altLabels: {
|
|
303
|
+
// mutationOnly: 'SSM',
|
|
304
|
+
// cnvOnly: 'CNV',
|
|
305
|
+
// },
|
|
306
|
+
value: "a",
|
|
307
|
+
order: 1,
|
|
308
|
+
// this is used for list order as a sorter option in a dropdown
|
|
309
|
+
sortPriority: [
|
|
310
|
+
{
|
|
311
|
+
label: `For each gene mutation, sort ${l.samples} by matching data`,
|
|
312
|
+
types: ["geneVariant"],
|
|
313
|
+
tiebreakers: [
|
|
314
|
+
{
|
|
315
|
+
skip: !s.mutationClasses.includes("Fuserna"),
|
|
316
|
+
// not visible, cannot be enabled
|
|
317
|
+
label: `${l.Samples} with Fusion RNASeq > without`,
|
|
318
|
+
filter: {
|
|
319
|
+
values: [
|
|
320
|
+
{
|
|
321
|
+
dt: dtfusionrna
|
|
322
|
+
}
|
|
323
|
+
]
|
|
324
|
+
},
|
|
325
|
+
by: "class",
|
|
326
|
+
isOrdered: false,
|
|
327
|
+
order: [
|
|
328
|
+
"Fuserna"
|
|
329
|
+
/*'WT', 'Blank'*/
|
|
330
|
+
]
|
|
331
|
+
},
|
|
332
|
+
{
|
|
333
|
+
label: `${l.Samples} with truncating mutations > without`,
|
|
334
|
+
filter: {
|
|
335
|
+
values: [
|
|
336
|
+
{
|
|
337
|
+
dt: dtsnvindel
|
|
338
|
+
}
|
|
339
|
+
]
|
|
340
|
+
},
|
|
341
|
+
by: "class",
|
|
342
|
+
isOrdered: false,
|
|
343
|
+
order: [
|
|
344
|
+
...s.truncatingMutations
|
|
345
|
+
// // truncating
|
|
346
|
+
// 'F', // FRAMESHIFT
|
|
347
|
+
// 'N', // NONSENSE
|
|
348
|
+
// 'L', // SPLICE
|
|
349
|
+
// 'P', // SPLICE_REGION
|
|
350
|
+
// // indel
|
|
351
|
+
// 'D', // PROTEINDEL
|
|
352
|
+
// 'I', // PROTEININS
|
|
353
|
+
// 'ProteinAltering',
|
|
354
|
+
// // point
|
|
355
|
+
// 'M' // MISSENSE
|
|
356
|
+
],
|
|
357
|
+
// do not have the option to add unused protein-changing mutations,
|
|
358
|
+
// because the "truncating" label for this tiebreaker will not make sense
|
|
359
|
+
notUsed: []
|
|
360
|
+
},
|
|
361
|
+
{
|
|
362
|
+
label: `${l.Samples} with CNV data > without`,
|
|
363
|
+
mayToggle: true,
|
|
364
|
+
filter: {
|
|
365
|
+
values: [
|
|
366
|
+
{
|
|
367
|
+
dt: dtcnv
|
|
368
|
+
}
|
|
369
|
+
]
|
|
370
|
+
},
|
|
371
|
+
by: "class",
|
|
372
|
+
isOrdered: true,
|
|
373
|
+
disabled: true,
|
|
374
|
+
// visible, can be enabled
|
|
375
|
+
order: [mclasscnvAmp, mclasscnvHomozygousDel, mclasscnvgain, mclasscnvloss, mclasscnvloh]
|
|
376
|
+
},
|
|
377
|
+
{
|
|
378
|
+
disabled: false,
|
|
379
|
+
mayToggle: true,
|
|
380
|
+
label: `${l.Samples} with protein-changing mutations > without`,
|
|
381
|
+
filter: {
|
|
382
|
+
values: [
|
|
383
|
+
{
|
|
384
|
+
dt: dtsnvindel
|
|
385
|
+
}
|
|
386
|
+
]
|
|
387
|
+
},
|
|
388
|
+
by: "class",
|
|
389
|
+
isOrdered: false,
|
|
390
|
+
// by default, do not include truncating mutations here since they may
|
|
391
|
+
// already be used in the tiebreaker with truncating mutations
|
|
392
|
+
order: s.proteinChangingMutations.filter((mcls) => !s.truncatingMutations.includes(mcls)),
|
|
393
|
+
notUsed: s.truncatingMutations
|
|
394
|
+
}
|
|
395
|
+
]
|
|
396
|
+
},
|
|
397
|
+
{
|
|
398
|
+
label: `For each dictionary variable, sort ${l.samples} by matching data`,
|
|
399
|
+
types: ["categorical", "integer", "float", "survival"],
|
|
400
|
+
tiebreakers: [
|
|
401
|
+
{
|
|
402
|
+
label: "Values",
|
|
403
|
+
by: "values"
|
|
404
|
+
}
|
|
405
|
+
]
|
|
406
|
+
}
|
|
407
|
+
]
|
|
408
|
+
};
|
|
409
|
+
sortOptions.name = {
|
|
410
|
+
label: `By ${l.sample} name, ID, or label`,
|
|
411
|
+
value: "name",
|
|
412
|
+
order: Object.values(sortOptions).length
|
|
413
|
+
};
|
|
414
|
+
return sortOptions;
|
|
415
|
+
}
|
|
416
|
+
function getSampleGroupSorter(self) {
|
|
417
|
+
const s = self.settings.matrix;
|
|
418
|
+
if (s.sortSampleGrpsBy == "hits")
|
|
419
|
+
return (a, b) => {
|
|
420
|
+
if (a.lst.length && !b.lst.length) return -1;
|
|
421
|
+
if (!a.lst.length && b.lst.length) return 1;
|
|
422
|
+
return b.totalCountedValues - a.totalCountedValues;
|
|
423
|
+
};
|
|
424
|
+
if (s.sortSampleGrpsBy == "sampleCount")
|
|
425
|
+
return (a, b) => {
|
|
426
|
+
if (a.lst.length && !b.lst.length) return -1;
|
|
427
|
+
if (!a.lst.length && b.lst.length) return 1;
|
|
428
|
+
if (a.lst.length == b.lst.length) {
|
|
429
|
+
return defaultSorter(a, b);
|
|
430
|
+
}
|
|
431
|
+
return b.lst.length - a.lst.length;
|
|
432
|
+
};
|
|
433
|
+
if (!self.config.divideBy?.$id) return defaultSorter;
|
|
434
|
+
const ref = self.data.refs.byTermId[self.config.divideBy.$id];
|
|
435
|
+
if (ref && !ref.keyOrder) ref.keyOrder = ref.bins ? ref.bins.map((b) => b.name) : [];
|
|
436
|
+
const predefinedKeyOrder = self.data.refs.byTermId[self.config.divideBy.$id]?.keyOrder;
|
|
437
|
+
if (!predefinedKeyOrder) return defaultSorter;
|
|
438
|
+
return (a, b) => {
|
|
439
|
+
a.order = predefinedKeyOrder.indexOf(a.id);
|
|
440
|
+
if (a.order == -1) delete a.order;
|
|
441
|
+
b.order = predefinedKeyOrder.indexOf(b.id);
|
|
442
|
+
if (b.order == -1) delete b.order;
|
|
443
|
+
if ("order" in a && "order" in b) return a.order - b.order;
|
|
444
|
+
if ("order" in a) return -1;
|
|
445
|
+
if ("order" in b) return 1;
|
|
446
|
+
if (a.tw?.term?.values?.[a.id]?.order && b.tw?.term?.values?.[b.id]?.order) {
|
|
447
|
+
return a.tw.term.values[a.id].order - b.tw.term.values[b.id].order;
|
|
448
|
+
}
|
|
449
|
+
return defaultSorter(a, b);
|
|
450
|
+
};
|
|
451
|
+
}
|
|
452
|
+
function defaultSorter(a, b) {
|
|
453
|
+
return a.name < b.name ? -1 : 1;
|
|
454
|
+
}
|
|
455
|
+
function getMclassSorter(self) {
|
|
456
|
+
const s = self.settings.matrix;
|
|
457
|
+
const activeOption = s.sortOptions[s.sortSamplesBy].sortPriority ? s.sortOptions[s.sortSamplesBy] : s.sortOptions.a;
|
|
458
|
+
const mclassPriority = [];
|
|
459
|
+
activeOption.sortPriority.forEach((obj) => {
|
|
460
|
+
if (obj.types.includes("geneVariant")) {
|
|
461
|
+
obj.tiebreakers.forEach((tiebreaker) => {
|
|
462
|
+
if (tiebreaker.by == "class" && tiebreaker.order) {
|
|
463
|
+
mclassPriority.push(...tiebreaker.order.filter((t) => t !== "WT" && t !== "Blank"));
|
|
464
|
+
}
|
|
465
|
+
});
|
|
466
|
+
}
|
|
467
|
+
});
|
|
468
|
+
const sorter = (a, b) => {
|
|
469
|
+
const ai = mclassPriority.indexOf(a.class);
|
|
470
|
+
const bi = mclassPriority.indexOf(b.class);
|
|
471
|
+
return ai == -1 && bi == -1 ? 0 : mclassPriority.indexOf(a.class) == -1 ? 1 : mclassPriority.indexOf(b.class) == -1 ? -1 : mclassPriority.indexOf(a.class) - mclassPriority.indexOf(b.class);
|
|
472
|
+
};
|
|
473
|
+
return sorter;
|
|
474
|
+
}
|
|
475
|
+
function reshapeSortPriority(sortOption, labels) {
|
|
476
|
+
const l = labels;
|
|
477
|
+
let geneVariantsEntry;
|
|
478
|
+
for (const sp of sortOption.sortPriority) {
|
|
479
|
+
if (sp.types.includes("categorical")) {
|
|
480
|
+
if (!sp.label) sp.label = `For each dictionary variable, sort ${l.samples} by matching data`;
|
|
481
|
+
continue;
|
|
482
|
+
}
|
|
483
|
+
if (!sp.types?.includes("geneVariant")) continue;
|
|
484
|
+
if (!geneVariantsEntry) {
|
|
485
|
+
geneVariantsEntry = sp;
|
|
486
|
+
if (!sp.label) sp.label = `For each gene mutation, sort ${l.samples} by matching data`;
|
|
487
|
+
} else {
|
|
488
|
+
geneVariantsEntry.tiebreakers.push(...sp.tiebreakers);
|
|
489
|
+
sp.toBeDeleted = true;
|
|
490
|
+
}
|
|
491
|
+
}
|
|
492
|
+
for (const tb of geneVariantsEntry.tiebreakers) {
|
|
493
|
+
if (tb.filter?.values?.find((v) => v.dt == dtfusionrna)) {
|
|
494
|
+
const defaults = {
|
|
495
|
+
label: `${l.Samples} with Fusion RNASeq > without`,
|
|
496
|
+
isOrdered: true,
|
|
497
|
+
disabled: false,
|
|
498
|
+
mayToggle: true
|
|
499
|
+
};
|
|
500
|
+
Object.assign(tb, defaults, tb);
|
|
501
|
+
} else if (tb.filter?.values?.find((v) => v.dt == dtsnvindel)) {
|
|
502
|
+
const label = tb.order.includes(mclasscnvgain) || tb.order.includes(mclasscnvloss) ? `${l.Samples} with SSM + CNV > SSM only` : `${l.Samples} with mutations`;
|
|
503
|
+
const defaults = {
|
|
504
|
+
label,
|
|
505
|
+
isOrdered: true,
|
|
506
|
+
disabled: false,
|
|
507
|
+
mayToggle: true
|
|
508
|
+
};
|
|
509
|
+
Object.assign(tb, defaults, tb);
|
|
510
|
+
} else if (tb.order.length == 2 && tb.order.includes(mclasscnvgain) && tb.order.includes(mclasscnvloss)) {
|
|
511
|
+
const defaults = {
|
|
512
|
+
label: `${l.Samples} with CNV only > without`,
|
|
513
|
+
filter: { values: [{ dt: dtcnv }] },
|
|
514
|
+
by: "class",
|
|
515
|
+
isOrdered: true,
|
|
516
|
+
disabled: false,
|
|
517
|
+
mayToggle: true
|
|
518
|
+
};
|
|
519
|
+
Object.assign(tb, defaults, tb);
|
|
520
|
+
}
|
|
521
|
+
}
|
|
522
|
+
sortOption.sortPriority = sortOption.sortPriority.filter((sp) => !sp.toBeDeleted);
|
|
523
|
+
return sortOption;
|
|
524
|
+
}
|
|
525
|
+
|
|
526
|
+
export {
|
|
527
|
+
getSampleSorter,
|
|
528
|
+
getTermSorter,
|
|
529
|
+
getSortOptions,
|
|
530
|
+
getSampleGroupSorter,
|
|
531
|
+
getMclassSorter,
|
|
532
|
+
reshapeSortPriority
|
|
533
|
+
};
|
|
534
|
+
//# sourceMappingURL=chunk-5UMPBVA6.js.map
|
|
@@ -0,0 +1,56 @@
|
|
|
1
|
+
import {
|
|
2
|
+
sayerror
|
|
3
|
+
} from "./chunk-NVB7MQLH.js";
|
|
4
|
+
import {
|
|
5
|
+
TermTypeGroups
|
|
6
|
+
} from "./chunk-XYFDBYOY.js";
|
|
7
|
+
|
|
8
|
+
// termdb/handlers/singleCellCellType.ts
|
|
9
|
+
var SearchHandler = class {
|
|
10
|
+
async init(opts) {
|
|
11
|
+
this.validateOpts(opts);
|
|
12
|
+
this.callback = opts.callback;
|
|
13
|
+
this.app = opts.app;
|
|
14
|
+
const holder = opts.holder.append("div").style("padding", "10px 0px");
|
|
15
|
+
const scctTerms = opts.app.vocabApi.termdbConfig?.termType2terms?.[TermTypeGroups.SINGLECELL_CELLTYPE];
|
|
16
|
+
if (!scctTerms) {
|
|
17
|
+
sayerror(
|
|
18
|
+
holder,
|
|
19
|
+
`termType2terms[${TermTypeGroups.SINGLECELL_CELLTYPE}]:[] is required in termdbConfig for singleCellCellType handler`
|
|
20
|
+
);
|
|
21
|
+
return;
|
|
22
|
+
}
|
|
23
|
+
const usecaseConfig = opts.usecase?.specialCase?.config;
|
|
24
|
+
const plotName = usecaseConfig?.name;
|
|
25
|
+
let filteredTerms = [];
|
|
26
|
+
if (plotName) {
|
|
27
|
+
filteredTerms = scctTerms.filter((t) => t.plot == plotName);
|
|
28
|
+
} else {
|
|
29
|
+
filteredTerms = scctTerms.map((t) => Object.assign(t, { label: `${t.name} (${t.plot})` }));
|
|
30
|
+
}
|
|
31
|
+
for (const t of filteredTerms) {
|
|
32
|
+
holder.append("div").classed("termdiv", true).style("padding", "0px 5px").append("div").classed("termlabel sja_filter_tag_btn sja_tree_click_term ts_pill", true).style("display", "inline-block").style("padding", "5px 8px").style("margin", "1px 0px").style("border-radius", "6px").text(t.label || t.name).on("click", () => {
|
|
33
|
+
const term = this.makeTerm(t, usecaseConfig);
|
|
34
|
+
this.callback(term);
|
|
35
|
+
});
|
|
36
|
+
}
|
|
37
|
+
}
|
|
38
|
+
makeTerm(_term, usecaseConfig) {
|
|
39
|
+
const term = { ..._term };
|
|
40
|
+
if (!term.sample && usecaseConfig?.sample) term.sample = usecaseConfig.sample;
|
|
41
|
+
return term;
|
|
42
|
+
}
|
|
43
|
+
validateOpts(opts) {
|
|
44
|
+
if (opts.callback == null) throw new Error("callback is required");
|
|
45
|
+
if (opts.app == null) throw new Error("app is required");
|
|
46
|
+
if (opts.holder == null) throw new Error("holder is required");
|
|
47
|
+
if (opts.usecase == null) throw new Error("usecase is required");
|
|
48
|
+
if (!opts.app.vocabApi.termdbConfig?.termType2terms)
|
|
49
|
+
throw new Error("termType2terms is required in termdbConfig for singleCellCellType handler");
|
|
50
|
+
}
|
|
51
|
+
};
|
|
52
|
+
|
|
53
|
+
export {
|
|
54
|
+
SearchHandler
|
|
55
|
+
};
|
|
56
|
+
//# sourceMappingURL=chunk-64FGLSIM.js.map
|
|
@@ -0,0 +1,7 @@
|
|
|
1
|
+
{
|
|
2
|
+
"version": 3,
|
|
3
|
+
"sources": ["../termdb/handlers/singleCellCellType.ts"],
|
|
4
|
+
"sourcesContent": ["import type { AppApi } from '#rx'\nimport { TermTypeGroups } from '#shared/terms.js'\nimport { sayerror } from '#dom'\n\nexport class SearchHandler {\n\tcallback?: (f?: any) => void\n\tapp?: AppApi\n\n\tasync init(opts) {\n\t\tthis.validateOpts(opts)\n\t\tthis.callback = opts.callback\n\t\tthis.app = opts.app\n\n\t\tconst holder = opts.holder.append('div').style('padding', '10px 0px')\n\t\tconst scctTerms = opts.app.vocabApi.termdbConfig?.termType2terms?.[TermTypeGroups.SINGLECELL_CELLTYPE]\n\t\tif (!scctTerms) {\n\t\t\tsayerror(\n\t\t\t\tholder,\n\t\t\t\t`termType2terms[${TermTypeGroups.SINGLECELL_CELLTYPE}]:[] is required in termdbConfig for singleCellCellType handler`\n\t\t\t)\n\t\t\treturn\n\t\t}\n\t\tconst usecaseConfig = opts.usecase?.specialCase?.config\n\t\tconst plotName = usecaseConfig?.name\n\t\tlet filteredTerms: any[] = []\n\t\tif (plotName) {\n\t\t\tfilteredTerms = scctTerms.filter(t => t.plot == plotName)\n\t\t} else {\n\t\t\tfilteredTerms = scctTerms.map(t => Object.assign(t, { label: `${t.name} (${t.plot})` }))\n\t\t}\n\n\t\tfor (const t of filteredTerms) {\n\t\t\tholder\n\t\t\t\t/** The divs and styling duplicates the appearance of the\n\t\t\t\t * tree terms. The tree is NOT called for this handler. */\n\t\t\t\t.append('div')\n\t\t\t\t.classed('termdiv', true)\n\t\t\t\t.style('padding', '0px 5px')\n\t\t\t\t.append('div')\n\t\t\t\t.classed('termlabel sja_filter_tag_btn sja_tree_click_term ts_pill', true)\n\t\t\t\t.style('display', 'inline-block')\n\t\t\t\t.style('padding', '5px 8px')\n\t\t\t\t.style('margin', '1px 0px')\n\t\t\t\t.style('border-radius', '6px')\n\t\t\t\t//End duplicated pill styling\n\t\t\t\t.text(t.label || t.name)\n\t\t\t\t.on('click', () => {\n\t\t\t\t\tconst term = this.makeTerm(t, usecaseConfig)\n\t\t\t\t\tthis.callback!(term)\n\t\t\t\t})\n\t\t}\n\t}\n\n\tmakeTerm(_term, usecaseConfig) {\n\t\tconst term = { ..._term }\n\t\tif (!term.sample && usecaseConfig?.sample) term.sample = usecaseConfig.sample\n\t\treturn term\n\t}\n\n\tvalidateOpts(opts) {\n\t\tif (opts.callback == null) throw new Error('callback is required')\n\t\tif (opts.app == null) throw new Error('app is required')\n\t\tif (opts.holder == null) throw new Error('holder is required')\n\t\tif (opts.usecase == null) throw new Error('usecase is required')\n\t\tif (!opts.app.vocabApi.termdbConfig?.termType2terms)\n\t\t\tthrow new Error('termType2terms is required in termdbConfig for singleCellCellType handler')\n\t}\n}\n"],
|
|
5
|
+
"mappings": ";;;;;;;;AAIO,IAAM,gBAAN,MAAoB;AAAA,EAI1B,MAAM,KAAK,MAAM;AAChB,SAAK,aAAa,IAAI;AACtB,SAAK,WAAW,KAAK;AACrB,SAAK,MAAM,KAAK;AAEhB,UAAM,SAAS,KAAK,OAAO,OAAO,KAAK,EAAE,MAAM,WAAW,UAAU;AACpE,UAAM,YAAY,KAAK,IAAI,SAAS,cAAc,iBAAiB,eAAe,mBAAmB;AACrG,QAAI,CAAC,WAAW;AACf;AAAA,QACC;AAAA,QACA,kBAAkB,eAAe,mBAAmB;AAAA,MACrD;AACA;AAAA,IACD;AACA,UAAM,gBAAgB,KAAK,SAAS,aAAa;AACjD,UAAM,WAAW,eAAe;AAChC,QAAI,gBAAuB,CAAC;AAC5B,QAAI,UAAU;AACb,sBAAgB,UAAU,OAAO,OAAK,EAAE,QAAQ,QAAQ;AAAA,IACzD,OAAO;AACN,sBAAgB,UAAU,IAAI,OAAK,OAAO,OAAO,GAAG,EAAE,OAAO,GAAG,EAAE,IAAI,KAAK,EAAE,IAAI,IAAI,CAAC,CAAC;AAAA,IACxF;AAEA,eAAW,KAAK,eAAe;AAC9B,aAGE,OAAO,KAAK,EACZ,QAAQ,WAAW,IAAI,EACvB,MAAM,WAAW,SAAS,EAC1B,OAAO,KAAK,EACZ,QAAQ,4DAA4D,IAAI,EACxE,MAAM,WAAW,cAAc,EAC/B,MAAM,WAAW,SAAS,EAC1B,MAAM,UAAU,SAAS,EACzB,MAAM,iBAAiB,KAAK,EAE5B,KAAK,EAAE,SAAS,EAAE,IAAI,EACtB,GAAG,SAAS,MAAM;AAClB,cAAM,OAAO,KAAK,SAAS,GAAG,aAAa;AAC3C,aAAK,SAAU,IAAI;AAAA,MACpB,CAAC;AAAA,IACH;AAAA,EACD;AAAA,EAEA,SAAS,OAAO,eAAe;AAC9B,UAAM,OAAO,EAAE,GAAG,MAAM;AACxB,QAAI,CAAC,KAAK,UAAU,eAAe,OAAQ,MAAK,SAAS,cAAc;AACvE,WAAO;AAAA,EACR;AAAA,EAEA,aAAa,MAAM;AAClB,QAAI,KAAK,YAAY,KAAM,OAAM,IAAI,MAAM,sBAAsB;AACjE,QAAI,KAAK,OAAO,KAAM,OAAM,IAAI,MAAM,iBAAiB;AACvD,QAAI,KAAK,UAAU,KAAM,OAAM,IAAI,MAAM,oBAAoB;AAC7D,QAAI,KAAK,WAAW,KAAM,OAAM,IAAI,MAAM,qBAAqB;AAC/D,QAAI,CAAC,KAAK,IAAI,SAAS,cAAc;AACpC,YAAM,IAAI,MAAM,2EAA2E;AAAA,EAC7F;AACD;",
|
|
6
|
+
"names": []
|
|
7
|
+
}
|