@sjcrh/proteinpaint-client 2.181.0 → 2.183.0

package/dist/chunk-D4QFQQWJ.js

@@ -0,0 +1,170 @@
+import {
+  getEmptyCell,
+  maySetEmptyCell,
+  setCellProps
+} from "./chunk-QMI222IJ.js";
+import {
+  TermTypeGroups
+} from "./chunk-XYFDBYOY.js";
+import {
+  __export
+} from "./chunk-HFNDKYVF.js";
+
+// plots/matrix/matrix.serieses.js
+var matrix_serieses_exports = {};
+__export(matrix_serieses_exports, {
+  getSerieses: () => getSerieses
+});
+function getSerieses(data) {
+  const s = this.settings.matrix;
+  const serieses = [];
+  const { colw, dx, dy, xMin, xMax } = this.dimensions;
+  const dvt = this.config.divideBy || {};
+  const divideByTermId = "id" in dvt ? dvt.id : dvt.name;
+  const legendGroups = {};
+  this.colorScaleByTermId = {};
+  for (const t of this.termOrder) {
+    const $id = t.tw.$id;
+    const termid = "id" in t.tw.term ? t.tw.term.id : t.tw.term.name;
+    const isDivideByTerm = termid === divideByTermId;
+    const emptyGridCells = [];
+    const cellht = t.grp.type == "hierCluster" ? s.clusterRowh : dy;
+    const htAdjust = t.grp.type == "hierCluster" ? 0 : t.totalHtAdjustments;
+    const y = s.transpose ? 0 : t.totalIndex * cellht + t.visibleGrpIndex * s.rowgspace + htAdjust;
+    const twSpecificSettings = this.config.settings.matrix.twSpecificSettings;
+    const hoverY0 = (twSpecificSettings[$id]?.contBarGap || 0) + y;
+    const series = {
+      t,
+      tw: t.tw,
+      cells: [],
+      y,
+      hoverY0,
+      hoverY1: hoverY0 + (twSpecificSettings[$id]?.contBarH || cellht)
+    };
+    for (const so of this.unfilteredSampleOrder) {
+      const { totalIndex, grpIndex, row } = so;
+      series.x = !s.transpose ? 0 : t.totalIndex * dx + t.visibleGrpIndex * s.colgspace;
+      const anno = row[$id];
+      const cellTemplate = {
+        s: so,
+        sample: row.sample,
+        tw: t.tw,
+        term: t.tw.term,
+        termid,
+        $id,
+        totalIndex,
+        grpIndex,
+        row,
+        t,
+        seriesY: y
+      };
+      if (!anno) {
+        if (!so.grp.isExcluded && (s.useCanvas || so.grp)) {
+          const cell = getEmptyCell(cellTemplate, s, this.dimensions);
+          series.cells.push(cell);
+        }
+        continue;
+      }
+      const key = anno.key;
+      const values = anno.filteredValues || anno.values || [anno.value];
+      const numRects = s.cellEncoding == "oncoprint" ? 1 : values.length;
+      const height = !s.transpose ? s.rowh / numRects : colw;
+      const width = !s.transpose ? colw : colw / values.length;
+      const siblingCells = [];
+      if (!anno || !anno.renderedValues?.length) {
+        if (!so.grp.isExcluded && (s.useCanvas || so.grp)) {
+          const cell = getEmptyCell(cellTemplate, s, this.dimensions);
+          series.cells.push(cell);
+        }
+        continue;
+      }
+      for (const [i, value] of values.entries()) {
+        const cell = Object.assign({ key, siblingCells }, cellTemplate);
+        cell.valueIndex = i;
+        let legend;
+        if (typeof t.tw.setCellProps == "function") {
+          legend = t.tw.setCellProps(cell, anno, value, s, t, this, width, height, dx, dy, i);
+        } else {
+          const cellProps = t.grp.type == "hierCluster" ? setCellProps["hierCluster"] : t.tw.term.type == "samplelst" ? setCellProps["categorical"] : setCellProps[t.tw.term.type];
+          legend = cellProps(cell, t.tw, anno, value, s, t, this, width, height, dx, dy, i);
+        }
+        if (!s.useCanvas && (cell.x + cell.width < xMin || cell.x - cell.width > xMax)) continue;
+        if (legend) {
+          for (const l of [legendGroups, so.grp.legendGroups]) {
+            if (!l) continue;
+            if (!l[legend.group]) {
+              l[legend.group] = {
+                ref: legend.ref,
+                values: {},
+                order: legend.order,
+                $id,
+                origin: legend.entry.origin
+              };
+              if (legend.entry.dt) l[legend.group].dt = [legend.entry.dt];
+            }
+            const lg = l[legend.group];
+            if (lg.dt && !lg.dt.includes(legend.entry.dt)) lg.dt.push(legend.entry.dt);
+            const legendK = legend.entry.origin ? legend.entry.origin + legend.value : legend.value;
+            if (!lg.values[legendK]) {
+              lg.values[legendK] = JSON.parse(JSON.stringify(legend.entry));
+              if (legend.entry.scale) lg.values[legendK].scale = legend.entry.scale;
+            }
+            if (!lg.values[legendK].samples) lg.values[legendK].samples = /* @__PURE__ */ new Set();
+            if (t.tw.term.name === TermTypeGroups.MUTATION_SIGNATURE) {
+              if (value?.value > 0) lg.values[legendK].samples.add(row.sample);
+            } else lg.values[legendK].samples.add(row.sample);
+            if (isDivideByTerm) {
+              lg.values[legend.value].isExcluded = so.grp.isExcluded;
+            }
+          }
+        }
+        if (!so.grp.isExcluded) {
+          if (anno.renderedValues.includes(value)) series.cells.push(cell);
+          siblingCells.push(cell);
+        }
+      }
+      if (s.showGrid == "rect" && !so.grp.isExcluded) {
+        const cell = t.grp.type == "hierCluster" ? getEmptyCell(cellTemplate, s, this.dimensions) : maySetEmptyCell[t.tw.term.type]?.(siblingCells, cellTemplate, s, this.dimensions);
+        if (cell) emptyGridCells.push(cell);
+      }
+    }
+    if (emptyGridCells.length) series.cells.unshift(...emptyGridCells);
+    if (series.cells.length) serieses.push(series);
+  }
+  addAllHiddenLegendGroups(legendGroups, this);
+  this.legendData = this.getLegendData(legendGroups, data.refs, this);
+  for (const grp of this.sampleGroups) {
+    grp.legendData = this.getLegendData(grp.legendGroups, data.refs, this);
+  }
+  return serieses;
+}
+function addAllHiddenLegendGroups(legendGroups, self) {
+  for (const valueFilter of self.config.legendValueFilter.lst) {
+    if (valueFilter.tvs.term.type == "categorical" && !legendGroups[valueFilter.tvs.term.$id]) {
+      legendGroups[valueFilter.tvs.term.$id] = {
+        ref: {},
+        values: {},
+        $id: valueFilter.tvs.term.$id
+      };
+    } else if (valueFilter.tvs.term.type == "geneVariant" && !legendGroups[valueFilter.legendGrpName]) {
+      legendGroups[valueFilter.legendGrpName] = {
+        ref: {},
+        values: {},
+        dt: [valueFilter.tvs.values[0].dt],
+        origin: valueFilter.tvs.values[0].origin
+      };
+    } else if ((valueFilter.tvs.term.type == "integer" || valueFilter.tvs.term.type == "float") && !legendGroups[valueFilter.tvs.term.$id]) {
+      legendGroups[valueFilter.tvs.term.$id] = {
+        ref: {},
+        values: {},
+        $id: valueFilter.tvs.term.$id
+      };
+    }
+  }
+}
+
+export {
+  getSerieses,
+  matrix_serieses_exports
+};
+//# sourceMappingURL=chunk-D4QFQQWJ.js.map

package/dist/chunk-DGMK7SXX.js

@@ -0,0 +1,203 @@
+import {
+  tkt
+} from "./chunk-OXJ2TWDO.js";
+import {
+  stratinput
+} from "./chunk-2K5DSRBJ.js";
+import {
+  stratify_default
+} from "./chunk-TOU7EVFQ.js";
+
+// src/vcf.tkconvert.js
+function vcf2dstk(arg) {
+  const ds = {
+    id2vcf: {},
+    label: arg.name || "Unnamed VCF file"
+  };
+  let vcfobj;
+  if (arg.file) {
+    const id = Math.random().toString();
+    vcfobj = {
+      file: arg.file,
+      indexURL: arg.indexURL,
+      vcfid: id
+    };
+    ds.id2vcf[id] = vcfobj;
+  } else if (arg.url) {
+    const id = Math.random().toString();
+    vcfobj = {
+      url: arg.url,
+      indexURL: arg.indexURL,
+      vcfid: id
+    };
+    ds.id2vcf[id] = vcfobj;
+  } else {
+    return ["no .file or .url"];
+  }
+  vcfobj.headernotloaded = true;
+  if (arg.samplenamemap) {
+    vcfobj.samplenamemap = arg.samplenamemap;
+  }
+  if (arg.variant2img) {
+    if (!arg.variant2img.path) return [".path missing from .variant2img{}"];
+  }
+  const tk = {
+    type: tkt.ds,
+    // to be loaded by loadvcftk() as a custom track, rather than "/dsdata" for official ds
+    isvcf: true,
+    name: ds.label,
+    ds,
+    populationfrequencyfilter: arg.populationfrequencyfilter,
+    vcfinfofilter: arg.vcfinfofilter,
+    itemlabelname: arg.itemlabelname,
+    viewrangeupperlimit: arg.viewrangeupperlimit,
+    variant2img: arg.variant2img,
+    axisheight: arg.axisheight
+  };
+  if (arg.url4variant) {
+    const err = check_url4variant(arg.url4variant);
+    if (err) return [".url4variant error: " + err];
+    tk.url4variant = arg.url4variant;
+  }
+  if (arg.button4variant) {
+    const err = check_button4variant(arg.button4variant);
+    if (err) return [".button4variant error: " + err];
+    tk.button4variant = arg.button4variant;
+  }
+  if (arg.sampleannotation) {
+    const sn = arg.sampleannotation;
+    if (!sn.annotation) return [".annotation{} missing from .sampleannotation"];
+    if (sn.levels) {
+      if (!Array.isArray(sn.levels)) return [".sampleannotation.levels should be array"];
+      const lst = [];
+      for (const sample in sn.annotation) {
+        const o = { sample_name: sample };
+        for (const k in sn.annotation[sample]) {
+          o[k] = sn.annotation[sample][k];
+        }
+        lst.push(o);
+      }
+      const nodes = stratinput(lst, sn.levels);
+      sn.root = stratify_default()(nodes);
+      sn.root.sum((i) => i.value);
+    }
+    if (sn.variantsunburst) {
+      if (!sn.levels) return [".levels missing when .variantsunburst is on from .sampleannotation"];
+    }
+    tk.ds.cohort = sn;
+  }
+  if (arg.vcfcohorttrack) {
+    if (!arg.vcfcohorttrack.file && !arg.vcfcohorttrack.url) return ["no .file or .url provided from .vcfcohorttrack"];
+    tk.ds.vcfcohorttrack = arg.vcfcohorttrack;
+  }
+  if (arg.germline2dvafplot) {
+    if (!arg.germline2dvafplot.individualkey) return [".individualkey missing from germline2dvafplot"];
+    if (!arg.germline2dvafplot.sampletypekey) return [".sampletypekey missing from germline2dvafplot"];
+    if (!arg.germline2dvafplot.xsampletype) return [".xsampletype missing from germline2dvafplot"];
+    if (!arg.germline2dvafplot.yleftsampletype) return [".yleftsampletype missing from germline2dvafplot"];
+    if (arg.germline2dvafplot.yrightsampletype) {
+      if (arg.germline2dvafplot.yrightsampletype == arg.germline2dvafplot.yleftsampletype)
+        return [".yrightsampletype should not be same as yleftsampletype"];
+    }
+    tk.ds.germline2dvafplot = arg.germline2dvafplot;
+  }
+  if (arg.vaf2coverageplot) {
+    if (arg.vaf2coverageplot.categorykey) {
+      if (!arg.vaf2coverageplot.categories)
+        return [".categories missing when .categorykey is in use for .vaf2coverageplot"];
+    }
+    tk.ds.vaf2coverageplot = arg.vaf2coverageplot;
+  }
+  if (arg.genotype2boxplot) {
+    if (arg.genotype2boxplot.boxplotvaluekey) {
+    } else if (arg.genotype2boxplot.sampleannotationkey) {
+      if (!tk.ds.cohort) return ["sampleannotation missing when using genotype2boxplot.sampleannotationkey"];
+      if (!tk.ds.cohort.annotation)
+        return ["sampleannotation.annotation missing when using genotype2boxplot.sampleannotationkey"];
+      let found = false;
+      for (const k in tk.ds.cohort.annotation) {
+        if (arg.genotype2boxplot.sampleannotationkey in tk.ds.cohort.annotation[k]) {
+          found = true;
+          break;
+        }
+      }
+      if (!found) return [arg.genotype2boxplot.sampleannotationkey + " not found in any sample annotation"];
+    } else {
+      return ["incomplete instruction for genotype2boxplot"];
+    }
+    tk.ds.genotype2boxplot = arg.genotype2boxplot;
+  }
+  if (arg.discardsymbolicallele) {
+    tk.ds.discardsymbolicallele = true;
+  }
+  if (arg.samplebynumericvalue) {
+    if (!arg.samplebynumericvalue.attrkey) return ["attrkey missing from samplebynumericvalue"];
+    if (!tk.ds.cohort) return ["sampleannotation missing when using samplebynumericvalue"];
+    if (!tk.ds.cohort.annotation) return ["sampleannotation.annotation missing when using samplebynumericvalue"];
+    let found = false;
+    for (const k in tk.ds.cohort.annotation) {
+      if (Number.isFinite(tk.ds.cohort.annotation[k][arg.samplebynumericvalue.attrkey])) {
+        found = true;
+        break;
+      }
+    }
+    if (!found) return ["samplebynumericvalue.attrkey not found in any sample annotation"];
+    tk.ds.samplebynumericvalue = arg.samplebynumericvalue;
+  }
+  {
+    const g = arg.genotypebynumericvalue;
+    if (g) {
+      if (!g.refref) return [tk.name + ": refref missing from genotypebynumericvalue"];
+      if (!g.refalt) return [tk.name + ": refalt missing from genotypebynumericvalue"];
+      if (!g.altalt) return [tk.name + ": altalt missing from genotypebynumericvalue"];
+      if (!g.refref.infokey) return [tk.name + ": refref.infokey missing from genotypebynumericvalue"];
+      if (!g.refalt.infokey) return [tk.name + ": refalt.infokey missing from genotypebynumericvalue"];
+      if (!g.altalt.infokey) return [tk.name + ": altalt.infokey missing from genotypebynumericvalue"];
+      if (g.refref.genotypeCountInfokey || g.refalt.genotypeCountInfokey || g.altalt.genotypeCountInfokey) {
+        if (!g.refref.genotypeCountInfokey)
+          return [tk.name + ": genotypeCountInfokey missing from genotypebynumericvalue.refref{}"];
+        if (!g.refalt.genotypeCountInfokey)
+          return [tk.name + ": genotypeCountInfokey missing from genotypebynumericvalue.refalt{}"];
+        if (!g.altalt.genotypeCountInfokey)
+          return [tk.name + ": genotypeCountInfokey missing from genotypebynumericvalue.altalt{}"];
+      }
+      tk.ds.genotypebynumericvalue = g;
+    }
+  }
+  if (arg.pointdown) {
+    tk.aboveprotein = false;
+  }
+  if (arg.dstk_novcferror) {
+    tk.dstk_novcferror = true;
+  }
+  return [null, tk];
+}
+function check_url4variant(lst) {
+  if (!Array.isArray(lst)) return "value is not an array";
+  for (const item of lst) {
+    if (!item.makeurl) {
+      return ".makeurl missing";
+    }
+    if (typeof item.makeurl != "function") {
+      return ".makeurl must be a function";
+    }
+  }
+  return false;
+}
+function check_button4variant(lst) {
+  if (!Array.isArray(lst)) return "value is not an array";
+  for (const item of lst) {
+    if (!item.makebutton) {
+      return ".makebutton missing";
+    }
+    if (typeof item.makebutton != "function") {
+      return ".makebutton must be a function";
+    }
+  }
+  return false;
+}
+
+export {
+  vcf2dstk
+};
+//# sourceMappingURL=chunk-DGMK7SXX.js.map