@medplum/fhirtypes 0.3.0

package/dist/SubstanceSpecification.d.ts

@@ -0,0 +1,965 @@
+/*
+ * Generated by @medplum/generator
+ * Do not edit manually.
+ */
+
+import { Attachment } from './Attachment';
+import { CodeableConcept } from './CodeableConcept';
+import { DocumentReference } from './DocumentReference';
+import { Extension } from './Extension';
+import { Identifier } from './Identifier';
+import { Meta } from './Meta';
+import { Narrative } from './Narrative';
+import { Quantity } from './Quantity';
+import { Range } from './Range';
+import { Ratio } from './Ratio';
+import { Reference } from './Reference';
+import { Resource } from './Resource';
+import { Substance } from './Substance';
+import { SubstanceNucleicAcid } from './SubstanceNucleicAcid';
+import { SubstancePolymer } from './SubstancePolymer';
+import { SubstanceProtein } from './SubstanceProtein';
+import { SubstanceReferenceInformation } from './SubstanceReferenceInformation';
+import { SubstanceSourceMaterial } from './SubstanceSourceMaterial';
+
+/**
+ * The detailed description of a substance, typically at a level beyond
+ * what is used for prescribing.
+ */
+export interface SubstanceSpecification {
+
+  /**
+   * This is a SubstanceSpecification resource
+   */
+  readonly resourceType: 'SubstanceSpecification';
+
+  /**
+   * The logical id of the resource, as used in the URL for the resource.
+   * Once assigned, this value never changes.
+   */
+  readonly id?: string;
+
+  /**
+   * The metadata about the resource. This is content that is maintained by
+   * the infrastructure. Changes to the content might not always be
+   * associated with version changes to the resource.
+   */
+  readonly meta?: Meta;
+
+  /**
+   * A reference to a set of rules that were followed when the resource was
+   * constructed, and which must be understood when processing the content.
+   * Often, this is a reference to an implementation guide that defines the
+   * special rules along with other profiles etc.
+   */
+  readonly implicitRules?: string;
+
+  /**
+   * The base language in which the resource is written.
+   */
+  readonly language?: string;
+
+  /**
+   * A human-readable narrative that contains a summary of the resource and
+   * can be used to represent the content of the resource to a human. The
+   * narrative need not encode all the structured data, but is required to
+   * contain sufficient detail to make it "clinically safe" for a human to
+   * just read the narrative. Resource definitions may define what content
+   * should be represented in the narrative to ensure clinical safety.
+   */
+  readonly text?: Narrative;
+
+  /**
+   * These resources do not have an independent existence apart from the
+   * resource that contains them - they cannot be identified independently,
+   * and nor can they have their own independent transaction scope.
+   */
+  readonly contained?: Resource[];
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the resource. To make the use of extensions
+   * safe and manageable, there is a strict set of governance  applied to
+   * the definition and use of extensions. Though any implementer can
+   * define an extension, there is a set of requirements that SHALL be met
+   * as part of the definition of the extension.
+   */
+  readonly extension?: Extension[];
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the resource and that modifies the
+   * understanding of the element that contains it and/or the understanding
+   * of the containing element's descendants. Usually modifier elements
+   * provide negation or qualification. To make the use of extensions safe
+   * and manageable, there is a strict set of governance applied to the
+   * definition and use of extensions. Though any implementer is allowed to
+   * define an extension, there is a set of requirements that SHALL be met
+   * as part of the definition of the extension. Applications processing a
+   * resource are required to check for modifier extensions.
+   *
+   * Modifier extensions SHALL NOT change the meaning of any elements on
+   * Resource or DomainResource (including cannot change the meaning of
+   * modifierExtension itself).
+   */
+  readonly modifierExtension?: Extension[];
+
+  /**
+   * Identifier by which this substance is known.
+   */
+  readonly identifier?: Identifier;
+
+  /**
+   * High level categorization, e.g. polymer or nucleic acid.
+   */
+  readonly type?: CodeableConcept;
+
+  /**
+   * Status of substance within the catalogue e.g. approved.
+   */
+  readonly status?: CodeableConcept;
+
+  /**
+   * If the substance applies to only human or veterinary use.
+   */
+  readonly domain?: CodeableConcept;
+
+  /**
+   * Textual description of the substance.
+   */
+  readonly description?: string;
+
+  /**
+   * Supporting literature.
+   */
+  readonly source?: Reference<DocumentReference>[];
+
+  /**
+   * Textual comment about this record of a substance.
+   */
+  readonly comment?: string;
+
+  /**
+   * Moiety, for structural modifications.
+   */
+  readonly moiety?: SubstanceSpecificationMoiety[];
+
+  /**
+   * General specifications for this substance, including how it is related
+   * to other substances.
+   */
+  readonly property?: SubstanceSpecificationProperty[];
+
+  /**
+   * General information detailing this substance.
+   */
+  readonly referenceInformation?: Reference<SubstanceReferenceInformation>;
+
+  /**
+   * Structural information.
+   */
+  readonly structure?: SubstanceSpecificationStructure;
+
+  /**
+   * Codes associated with the substance.
+   */
+  readonly code?: SubstanceSpecificationCode[];
+
+  /**
+   * Names applicable to this substance.
+   */
+  readonly name?: SubstanceSpecificationName[];
+
+  /**
+   * The molecular weight or weight range (for proteins, polymers or
+   * nucleic acids).
+   */
+  readonly molecularWeight?: SubstanceSpecificationStructureIsotopeMolecularWeight[];
+
+  /**
+   * A link between this substance and another, with details of the
+   * relationship.
+   */
+  readonly relationship?: SubstanceSpecificationRelationship[];
+
+  /**
+   * Data items specific to nucleic acids.
+   */
+  readonly nucleicAcid?: Reference<SubstanceNucleicAcid>;
+
+  /**
+   * Data items specific to polymers.
+   */
+  readonly polymer?: Reference<SubstancePolymer>;
+
+  /**
+   * Data items specific to proteins.
+   */
+  readonly protein?: Reference<SubstanceProtein>;
+
+  /**
+   * Material or taxonomic/anatomical source for the substance.
+   */
+  readonly sourceMaterial?: Reference<SubstanceSourceMaterial>;
+}
+
+/**
+ * Codes associated with the substance.
+ */
+export interface SubstanceSpecificationCode {
+
+  /**
+   * Unique id for the element within a resource (for internal references).
+   * This may be any string value that does not contain spaces.
+   */
+  readonly id?: string;
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element. To make the use of extensions
+   * safe and manageable, there is a strict set of governance  applied to
+   * the definition and use of extensions. Though any implementer can
+   * define an extension, there is a set of requirements that SHALL be met
+   * as part of the definition of the extension.
+   */
+  readonly extension?: Extension[];
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element and that modifies the
+   * understanding of the element in which it is contained and/or the
+   * understanding of the containing element's descendants. Usually
+   * modifier elements provide negation or qualification. To make the use
+   * of extensions safe and manageable, there is a strict set of governance
+   * applied to the definition and use of extensions. Though any
+   * implementer can define an extension, there is a set of requirements
+   * that SHALL be met as part of the definition of the extension.
+   * Applications processing a resource are required to check for modifier
+   * extensions.
+   *
+   * Modifier extensions SHALL NOT change the meaning of any elements on
+   * Resource or DomainResource (including cannot change the meaning of
+   * modifierExtension itself).
+   */
+  readonly modifierExtension?: Extension[];
+
+  /**
+   * The specific code.
+   */
+  readonly code?: CodeableConcept;
+
+  /**
+   * Status of the code assignment.
+   */
+  readonly status?: CodeableConcept;
+
+  /**
+   * The date at which the code status is changed as part of the
+   * terminology maintenance.
+   */
+  readonly statusDate?: string;
+
+  /**
+   * Any comment can be provided in this field, if necessary.
+   */
+  readonly comment?: string;
+
+  /**
+   * Supporting literature.
+   */
+  readonly source?: Reference<DocumentReference>[];
+}
+
+/**
+ * Moiety, for structural modifications.
+ */
+export interface SubstanceSpecificationMoiety {
+
+  /**
+   * Unique id for the element within a resource (for internal references).
+   * This may be any string value that does not contain spaces.
+   */
+  readonly id?: string;
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element. To make the use of extensions
+   * safe and manageable, there is a strict set of governance  applied to
+   * the definition and use of extensions. Though any implementer can
+   * define an extension, there is a set of requirements that SHALL be met
+   * as part of the definition of the extension.
+   */
+  readonly extension?: Extension[];
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element and that modifies the
+   * understanding of the element in which it is contained and/or the
+   * understanding of the containing element's descendants. Usually
+   * modifier elements provide negation or qualification. To make the use
+   * of extensions safe and manageable, there is a strict set of governance
+   * applied to the definition and use of extensions. Though any
+   * implementer can define an extension, there is a set of requirements
+   * that SHALL be met as part of the definition of the extension.
+   * Applications processing a resource are required to check for modifier
+   * extensions.
+   *
+   * Modifier extensions SHALL NOT change the meaning of any elements on
+   * Resource or DomainResource (including cannot change the meaning of
+   * modifierExtension itself).
+   */
+  readonly modifierExtension?: Extension[];
+
+  /**
+   * Role that the moiety is playing.
+   */
+  readonly role?: CodeableConcept;
+
+  /**
+   * Identifier by which this moiety substance is known.
+   */
+  readonly identifier?: Identifier;
+
+  /**
+   * Textual name for this moiety substance.
+   */
+  readonly name?: string;
+
+  /**
+   * Stereochemistry type.
+   */
+  readonly stereochemistry?: CodeableConcept;
+
+  /**
+   * Optical activity type.
+   */
+  readonly opticalActivity?: CodeableConcept;
+
+  /**
+   * Molecular formula.
+   */
+  readonly molecularFormula?: string;
+
+  /**
+   * Quantitative value for this moiety.
+   */
+  readonly amountQuantity?: Quantity;
+
+  /**
+   * Quantitative value for this moiety.
+   */
+  readonly amountString?: string;
+}
+
+/**
+ * Names applicable to this substance.
+ */
+export interface SubstanceSpecificationName {
+
+  /**
+   * Unique id for the element within a resource (for internal references).
+   * This may be any string value that does not contain spaces.
+   */
+  readonly id?: string;
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element. To make the use of extensions
+   * safe and manageable, there is a strict set of governance  applied to
+   * the definition and use of extensions. Though any implementer can
+   * define an extension, there is a set of requirements that SHALL be met
+   * as part of the definition of the extension.
+   */
+  readonly extension?: Extension[];
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element and that modifies the
+   * understanding of the element in which it is contained and/or the
+   * understanding of the containing element's descendants. Usually
+   * modifier elements provide negation or qualification. To make the use
+   * of extensions safe and manageable, there is a strict set of governance
+   * applied to the definition and use of extensions. Though any
+   * implementer can define an extension, there is a set of requirements
+   * that SHALL be met as part of the definition of the extension.
+   * Applications processing a resource are required to check for modifier
+   * extensions.
+   *
+   * Modifier extensions SHALL NOT change the meaning of any elements on
+   * Resource or DomainResource (including cannot change the meaning of
+   * modifierExtension itself).
+   */
+  readonly modifierExtension?: Extension[];
+
+  /**
+   * The actual name.
+   */
+  readonly name?: string;
+
+  /**
+   * Name type.
+   */
+  readonly type?: CodeableConcept;
+
+  /**
+   * The status of the name.
+   */
+  readonly status?: CodeableConcept;
+
+  /**
+   * If this is the preferred name for this substance.
+   */
+  readonly preferred?: boolean;
+
+  /**
+   * Language of the name.
+   */
+  readonly language?: CodeableConcept[];
+
+  /**
+   * The use context of this name for example if there is a different name
+   * a drug active ingredient as opposed to a food colour additive.
+   */
+  readonly domain?: CodeableConcept[];
+
+  /**
+   * The jurisdiction where this name applies.
+   */
+  readonly jurisdiction?: CodeableConcept[];
+
+  /**
+   * A synonym of this name.
+   */
+  readonly synonym?: SubstanceSpecificationName[];
+
+  /**
+   * A translation for this name.
+   */
+  readonly translation?: SubstanceSpecificationName[];
+
+  /**
+   * Details of the official nature of this name.
+   */
+  readonly official?: SubstanceSpecificationNameOfficial[];
+
+  /**
+   * Supporting literature.
+   */
+  readonly source?: Reference<DocumentReference>[];
+}
+
+/**
+ * Details of the official nature of this name.
+ */
+export interface SubstanceSpecificationNameOfficial {
+
+  /**
+   * Unique id for the element within a resource (for internal references).
+   * This may be any string value that does not contain spaces.
+   */
+  readonly id?: string;
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element. To make the use of extensions
+   * safe and manageable, there is a strict set of governance  applied to
+   * the definition and use of extensions. Though any implementer can
+   * define an extension, there is a set of requirements that SHALL be met
+   * as part of the definition of the extension.
+   */
+  readonly extension?: Extension[];
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element and that modifies the
+   * understanding of the element in which it is contained and/or the
+   * understanding of the containing element's descendants. Usually
+   * modifier elements provide negation or qualification. To make the use
+   * of extensions safe and manageable, there is a strict set of governance
+   * applied to the definition and use of extensions. Though any
+   * implementer can define an extension, there is a set of requirements
+   * that SHALL be met as part of the definition of the extension.
+   * Applications processing a resource are required to check for modifier
+   * extensions.
+   *
+   * Modifier extensions SHALL NOT change the meaning of any elements on
+   * Resource or DomainResource (including cannot change the meaning of
+   * modifierExtension itself).
+   */
+  readonly modifierExtension?: Extension[];
+
+  /**
+   * Which authority uses this official name.
+   */
+  readonly authority?: CodeableConcept;
+
+  /**
+   * The status of the official name.
+   */
+  readonly status?: CodeableConcept;
+
+  /**
+   * Date of official name change.
+   */
+  readonly date?: string;
+}
+
+/**
+ * General specifications for this substance, including how it is related
+ * to other substances.
+ */
+export interface SubstanceSpecificationProperty {
+
+  /**
+   * Unique id for the element within a resource (for internal references).
+   * This may be any string value that does not contain spaces.
+   */
+  readonly id?: string;
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element. To make the use of extensions
+   * safe and manageable, there is a strict set of governance  applied to
+   * the definition and use of extensions. Though any implementer can
+   * define an extension, there is a set of requirements that SHALL be met
+   * as part of the definition of the extension.
+   */
+  readonly extension?: Extension[];
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element and that modifies the
+   * understanding of the element in which it is contained and/or the
+   * understanding of the containing element's descendants. Usually
+   * modifier elements provide negation or qualification. To make the use
+   * of extensions safe and manageable, there is a strict set of governance
+   * applied to the definition and use of extensions. Though any
+   * implementer can define an extension, there is a set of requirements
+   * that SHALL be met as part of the definition of the extension.
+   * Applications processing a resource are required to check for modifier
+   * extensions.
+   *
+   * Modifier extensions SHALL NOT change the meaning of any elements on
+   * Resource or DomainResource (including cannot change the meaning of
+   * modifierExtension itself).
+   */
+  readonly modifierExtension?: Extension[];
+
+  /**
+   * A category for this property, e.g. Physical, Chemical, Enzymatic.
+   */
+  readonly category?: CodeableConcept;
+
+  /**
+   * Property type e.g. viscosity, pH, isoelectric point.
+   */
+  readonly code?: CodeableConcept;
+
+  /**
+   * Parameters that were used in the measurement of a property (e.g. for
+   * viscosity: measured at 20C with a pH of 7.1).
+   */
+  readonly parameters?: string;
+
+  /**
+   * A substance upon which a defining property depends (e.g. for
+   * solubility: in water, in alcohol).
+   */
+  readonly definingSubstanceReference?: Reference<SubstanceSpecification | Substance>;
+
+  /**
+   * A substance upon which a defining property depends (e.g. for
+   * solubility: in water, in alcohol).
+   */
+  readonly definingSubstanceCodeableConcept?: CodeableConcept;
+
+  /**
+   * Quantitative value for this property.
+   */
+  readonly amountQuantity?: Quantity;
+
+  /**
+   * Quantitative value for this property.
+   */
+  readonly amountString?: string;
+}
+
+/**
+ * A link between this substance and another, with details of the
+ * relationship.
+ */
+export interface SubstanceSpecificationRelationship {
+
+  /**
+   * Unique id for the element within a resource (for internal references).
+   * This may be any string value that does not contain spaces.
+   */
+  readonly id?: string;
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element. To make the use of extensions
+   * safe and manageable, there is a strict set of governance  applied to
+   * the definition and use of extensions. Though any implementer can
+   * define an extension, there is a set of requirements that SHALL be met
+   * as part of the definition of the extension.
+   */
+  readonly extension?: Extension[];
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element and that modifies the
+   * understanding of the element in which it is contained and/or the
+   * understanding of the containing element's descendants. Usually
+   * modifier elements provide negation or qualification. To make the use
+   * of extensions safe and manageable, there is a strict set of governance
+   * applied to the definition and use of extensions. Though any
+   * implementer can define an extension, there is a set of requirements
+   * that SHALL be met as part of the definition of the extension.
+   * Applications processing a resource are required to check for modifier
+   * extensions.
+   *
+   * Modifier extensions SHALL NOT change the meaning of any elements on
+   * Resource or DomainResource (including cannot change the meaning of
+   * modifierExtension itself).
+   */
+  readonly modifierExtension?: Extension[];
+
+  /**
+   * A pointer to another substance, as a resource or just a
+   * representational code.
+   */
+  readonly substanceReference?: Reference<SubstanceSpecification>;
+
+  /**
+   * A pointer to another substance, as a resource or just a
+   * representational code.
+   */
+  readonly substanceCodeableConcept?: CodeableConcept;
+
+  /**
+   * For example &quot;salt to parent&quot;, &quot;active moiety&quot;, &quot;starting material&quot;.
+   */
+  readonly relationship?: CodeableConcept;
+
+  /**
+   * For example where an enzyme strongly bonds with a particular
+   * substance, this is a defining relationship for that enzyme, out of
+   * several possible substance relationships.
+   */
+  readonly isDefining?: boolean;
+
+  /**
+   * A numeric factor for the relationship, for instance to express that
+   * the salt of a substance has some percentage of the active substance in
+   * relation to some other.
+   */
+  readonly amountQuantity?: Quantity;
+
+  /**
+   * A numeric factor for the relationship, for instance to express that
+   * the salt of a substance has some percentage of the active substance in
+   * relation to some other.
+   */
+  readonly amountRange?: Range;
+
+  /**
+   * A numeric factor for the relationship, for instance to express that
+   * the salt of a substance has some percentage of the active substance in
+   * relation to some other.
+   */
+  readonly amountRatio?: Ratio;
+
+  /**
+   * A numeric factor for the relationship, for instance to express that
+   * the salt of a substance has some percentage of the active substance in
+   * relation to some other.
+   */
+  readonly amountString?: string;
+
+  /**
+   * For use when the numeric.
+   */
+  readonly amountRatioLowLimit?: Ratio;
+
+  /**
+   * An operator for the amount, for example &quot;average&quot;, &quot;approximately&quot;,
+   * &quot;less than&quot;.
+   */
+  readonly amountType?: CodeableConcept;
+
+  /**
+   * Supporting literature.
+   */
+  readonly source?: Reference<DocumentReference>[];
+}
+
+/**
+ * Structural information.
+ */
+export interface SubstanceSpecificationStructure {
+
+  /**
+   * Unique id for the element within a resource (for internal references).
+   * This may be any string value that does not contain spaces.
+   */
+  readonly id?: string;
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element. To make the use of extensions
+   * safe and manageable, there is a strict set of governance  applied to
+   * the definition and use of extensions. Though any implementer can
+   * define an extension, there is a set of requirements that SHALL be met
+   * as part of the definition of the extension.
+   */
+  readonly extension?: Extension[];
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element and that modifies the
+   * understanding of the element in which it is contained and/or the
+   * understanding of the containing element's descendants. Usually
+   * modifier elements provide negation or qualification. To make the use
+   * of extensions safe and manageable, there is a strict set of governance
+   * applied to the definition and use of extensions. Though any
+   * implementer can define an extension, there is a set of requirements
+   * that SHALL be met as part of the definition of the extension.
+   * Applications processing a resource are required to check for modifier
+   * extensions.
+   *
+   * Modifier extensions SHALL NOT change the meaning of any elements on
+   * Resource or DomainResource (including cannot change the meaning of
+   * modifierExtension itself).
+   */
+  readonly modifierExtension?: Extension[];
+
+  /**
+   * Stereochemistry type.
+   */
+  readonly stereochemistry?: CodeableConcept;
+
+  /**
+   * Optical activity type.
+   */
+  readonly opticalActivity?: CodeableConcept;
+
+  /**
+   * Molecular formula.
+   */
+  readonly molecularFormula?: string;
+
+  /**
+   * Specified per moiety according to the Hill system, i.e. first C, then
+   * H, then alphabetical, each moiety separated by a dot.
+   */
+  readonly molecularFormulaByMoiety?: string;
+
+  /**
+   * Applicable for single substances that contain a radionuclide or a
+   * non-natural isotopic ratio.
+   */
+  readonly isotope?: SubstanceSpecificationStructureIsotope[];
+
+  /**
+   * The molecular weight or weight range (for proteins, polymers or
+   * nucleic acids).
+   */
+  readonly molecularWeight?: SubstanceSpecificationStructureIsotopeMolecularWeight;
+
+  /**
+   * Supporting literature.
+   */
+  readonly source?: Reference<DocumentReference>[];
+
+  /**
+   * Molecular structural representation.
+   */
+  readonly representation?: SubstanceSpecificationStructureRepresentation[];
+}
+
+/**
+ * Applicable for single substances that contain a radionuclide or a
+ * non-natural isotopic ratio.
+ */
+export interface SubstanceSpecificationStructureIsotope {
+
+  /**
+   * Unique id for the element within a resource (for internal references).
+   * This may be any string value that does not contain spaces.
+   */
+  readonly id?: string;
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element. To make the use of extensions
+   * safe and manageable, there is a strict set of governance  applied to
+   * the definition and use of extensions. Though any implementer can
+   * define an extension, there is a set of requirements that SHALL be met
+   * as part of the definition of the extension.
+   */
+  readonly extension?: Extension[];
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element and that modifies the
+   * understanding of the element in which it is contained and/or the
+   * understanding of the containing element's descendants. Usually
+   * modifier elements provide negation or qualification. To make the use
+   * of extensions safe and manageable, there is a strict set of governance
+   * applied to the definition and use of extensions. Though any
+   * implementer can define an extension, there is a set of requirements
+   * that SHALL be met as part of the definition of the extension.
+   * Applications processing a resource are required to check for modifier
+   * extensions.
+   *
+   * Modifier extensions SHALL NOT change the meaning of any elements on
+   * Resource or DomainResource (including cannot change the meaning of
+   * modifierExtension itself).
+   */
+  readonly modifierExtension?: Extension[];
+
+  /**
+   * Substance identifier for each non-natural or radioisotope.
+   */
+  readonly identifier?: Identifier;
+
+  /**
+   * Substance name for each non-natural or radioisotope.
+   */
+  readonly name?: CodeableConcept;
+
+  /**
+   * The type of isotopic substitution present in a single substance.
+   */
+  readonly substitution?: CodeableConcept;
+
+  /**
+   * Half life - for a non-natural nuclide.
+   */
+  readonly halfLife?: Quantity;
+
+  /**
+   * The molecular weight or weight range (for proteins, polymers or
+   * nucleic acids).
+   */
+  readonly molecularWeight?: SubstanceSpecificationStructureIsotopeMolecularWeight;
+}
+
+/**
+ * The molecular weight or weight range (for proteins, polymers or
+ * nucleic acids).
+ */
+export interface SubstanceSpecificationStructureIsotopeMolecularWeight {
+
+  /**
+   * Unique id for the element within a resource (for internal references).
+   * This may be any string value that does not contain spaces.
+   */
+  readonly id?: string;
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element. To make the use of extensions
+   * safe and manageable, there is a strict set of governance  applied to
+   * the definition and use of extensions. Though any implementer can
+   * define an extension, there is a set of requirements that SHALL be met
+   * as part of the definition of the extension.
+   */
+  readonly extension?: Extension[];
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element and that modifies the
+   * understanding of the element in which it is contained and/or the
+   * understanding of the containing element's descendants. Usually
+   * modifier elements provide negation or qualification. To make the use
+   * of extensions safe and manageable, there is a strict set of governance
+   * applied to the definition and use of extensions. Though any
+   * implementer can define an extension, there is a set of requirements
+   * that SHALL be met as part of the definition of the extension.
+   * Applications processing a resource are required to check for modifier
+   * extensions.
+   *
+   * Modifier extensions SHALL NOT change the meaning of any elements on
+   * Resource or DomainResource (including cannot change the meaning of
+   * modifierExtension itself).
+   */
+  readonly modifierExtension?: Extension[];
+
+  /**
+   * The method by which the molecular weight was determined.
+   */
+  readonly method?: CodeableConcept;
+
+  /**
+   * Type of molecular weight such as exact, average (also known as. number
+   * average), weight average.
+   */
+  readonly type?: CodeableConcept;
+
+  /**
+   * Used to capture quantitative values for a variety of elements. If only
+   * limits are given, the arithmetic mean would be the average. If only a
+   * single definite value for a given element is given, it would be
+   * captured in this field.
+   */
+  readonly amount?: Quantity;
+}
+
+/**
+ * Molecular structural representation.
+ */
+export interface SubstanceSpecificationStructureRepresentation {
+
+  /**
+   * Unique id for the element within a resource (for internal references).
+   * This may be any string value that does not contain spaces.
+   */
+  readonly id?: string;
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element. To make the use of extensions
+   * safe and manageable, there is a strict set of governance  applied to
+   * the definition and use of extensions. Though any implementer can
+   * define an extension, there is a set of requirements that SHALL be met
+   * as part of the definition of the extension.
+   */
+  readonly extension?: Extension[];
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element and that modifies the
+   * understanding of the element in which it is contained and/or the
+   * understanding of the containing element's descendants. Usually
+   * modifier elements provide negation or qualification. To make the use
+   * of extensions safe and manageable, there is a strict set of governance
+   * applied to the definition and use of extensions. Though any
+   * implementer can define an extension, there is a set of requirements
+   * that SHALL be met as part of the definition of the extension.
+   * Applications processing a resource are required to check for modifier
+   * extensions.
+   *
+   * Modifier extensions SHALL NOT change the meaning of any elements on
+   * Resource or DomainResource (including cannot change the meaning of
+   * modifierExtension itself).
+   */
+  readonly modifierExtension?: Extension[];
+
+  /**
+   * The type of structure (e.g. Full, Partial, Representative).
+   */
+  readonly type?: CodeableConcept;
+
+  /**
+   * The structural representation as text string in a format e.g. InChI,
+   * SMILES, MOLFILE, CDX.
+   */
+  readonly representation?: string;
+
+  /**
+   * An attached file with the structural representation.
+   */
+  readonly attachment?: Attachment;
+}