@medplum/fhirtypes 0.3.0

package/dist/SubstanceProtein.d.ts

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+/*
+ * Generated by @medplum/generator
+ * Do not edit manually.
+ */
+
+import { Attachment } from './Attachment';
+import { CodeableConcept } from './CodeableConcept';
+import { Extension } from './Extension';
+import { Identifier } from './Identifier';
+import { Meta } from './Meta';
+import { Narrative } from './Narrative';
+import { Resource } from './Resource';
+
+/**
+ * A SubstanceProtein is defined as a single unit of a linear amino acid
+ * sequence, or a combination of subunits that are either covalently
+ * linked or have a defined invariant stoichiometric relationship. This
+ * includes all synthetic, recombinant and purified SubstanceProteins of
+ * defined sequence, whether the use is therapeutic or prophylactic. This
+ * set of elements will be used to describe albumins, coagulation
+ * factors, cytokines, growth factors, peptide/SubstanceProtein hormones,
+ * enzymes, toxins, toxoids, recombinant vaccines, and immunomodulators.
+ */
+export interface SubstanceProtein {
+
+  /**
+   * This is a SubstanceProtein resource
+   */
+  readonly resourceType: 'SubstanceProtein';
+
+  /**
+   * The logical id of the resource, as used in the URL for the resource.
+   * Once assigned, this value never changes.
+   */
+  readonly id?: string;
+
+  /**
+   * The metadata about the resource. This is content that is maintained by
+   * the infrastructure. Changes to the content might not always be
+   * associated with version changes to the resource.
+   */
+  readonly meta?: Meta;
+
+  /**
+   * A reference to a set of rules that were followed when the resource was
+   * constructed, and which must be understood when processing the content.
+   * Often, this is a reference to an implementation guide that defines the
+   * special rules along with other profiles etc.
+   */
+  readonly implicitRules?: string;
+
+  /**
+   * The base language in which the resource is written.
+   */
+  readonly language?: string;
+
+  /**
+   * A human-readable narrative that contains a summary of the resource and
+   * can be used to represent the content of the resource to a human. The
+   * narrative need not encode all the structured data, but is required to
+   * contain sufficient detail to make it "clinically safe" for a human to
+   * just read the narrative. Resource definitions may define what content
+   * should be represented in the narrative to ensure clinical safety.
+   */
+  readonly text?: Narrative;
+
+  /**
+   * These resources do not have an independent existence apart from the
+   * resource that contains them - they cannot be identified independently,
+   * and nor can they have their own independent transaction scope.
+   */
+  readonly contained?: Resource[];
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the resource. To make the use of extensions
+   * safe and manageable, there is a strict set of governance  applied to
+   * the definition and use of extensions. Though any implementer can
+   * define an extension, there is a set of requirements that SHALL be met
+   * as part of the definition of the extension.
+   */
+  readonly extension?: Extension[];
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the resource and that modifies the
+   * understanding of the element that contains it and/or the understanding
+   * of the containing element's descendants. Usually modifier elements
+   * provide negation or qualification. To make the use of extensions safe
+   * and manageable, there is a strict set of governance applied to the
+   * definition and use of extensions. Though any implementer is allowed to
+   * define an extension, there is a set of requirements that SHALL be met
+   * as part of the definition of the extension. Applications processing a
+   * resource are required to check for modifier extensions.
+   *
+   * Modifier extensions SHALL NOT change the meaning of any elements on
+   * Resource or DomainResource (including cannot change the meaning of
+   * modifierExtension itself).
+   */
+  readonly modifierExtension?: Extension[];
+
+  /**
+   * The SubstanceProtein descriptive elements will only be used when a
+   * complete or partial amino acid sequence is available or derivable from
+   * a nucleic acid sequence.
+   */
+  readonly sequenceType?: CodeableConcept;
+
+  /**
+   * Number of linear sequences of amino acids linked through peptide
+   * bonds. The number of subunits constituting the SubstanceProtein shall
+   * be described. It is possible that the number of subunits can be
+   * variable.
+   */
+  readonly numberOfSubunits?: number;
+
+  /**
+   * The disulphide bond between two cysteine residues either on the same
+   * subunit or on two different subunits shall be described. The position
+   * of the disulfide bonds in the SubstanceProtein shall be listed in
+   * increasing order of subunit number and position within subunit
+   * followed by the abbreviation of the amino acids involved. The
+   * disulfide linkage positions shall actually contain the amino acid
+   * Cysteine at the respective positions.
+   */
+  readonly disulfideLinkage?: string[];
+
+  /**
+   * This subclause refers to the description of each subunit constituting
+   * the SubstanceProtein. A subunit is a linear sequence of amino acids
+   * linked through peptide bonds. The Subunit information shall be
+   * provided when the finished SubstanceProtein is a complex of multiple
+   * sequences; subunits are not used to delineate domains within a single
+   * sequence. Subunits are listed in order of decreasing length; sequences
+   * of the same length will be ordered by decreasing molecular weight;
+   * subunits that have identical sequences will be repeated multiple
+   * times.
+   */
+  readonly subunit?: SubstanceProteinSubunit[];
+}
+
+/**
+ * This subclause refers to the description of each subunit constituting
+ * the SubstanceProtein. A subunit is a linear sequence of amino acids
+ * linked through peptide bonds. The Subunit information shall be
+ * provided when the finished SubstanceProtein is a complex of multiple
+ * sequences; subunits are not used to delineate domains within a single
+ * sequence. Subunits are listed in order of decreasing length; sequences
+ * of the same length will be ordered by decreasing molecular weight;
+ * subunits that have identical sequences will be repeated multiple
+ * times.
+ */
+export interface SubstanceProteinSubunit {
+
+  /**
+   * Unique id for the element within a resource (for internal references).
+   * This may be any string value that does not contain spaces.
+   */
+  readonly id?: string;
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element. To make the use of extensions
+   * safe and manageable, there is a strict set of governance  applied to
+   * the definition and use of extensions. Though any implementer can
+   * define an extension, there is a set of requirements that SHALL be met
+   * as part of the definition of the extension.
+   */
+  readonly extension?: Extension[];
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element and that modifies the
+   * understanding of the element in which it is contained and/or the
+   * understanding of the containing element's descendants. Usually
+   * modifier elements provide negation or qualification. To make the use
+   * of extensions safe and manageable, there is a strict set of governance
+   * applied to the definition and use of extensions. Though any
+   * implementer can define an extension, there is a set of requirements
+   * that SHALL be met as part of the definition of the extension.
+   * Applications processing a resource are required to check for modifier
+   * extensions.
+   *
+   * Modifier extensions SHALL NOT change the meaning of any elements on
+   * Resource or DomainResource (including cannot change the meaning of
+   * modifierExtension itself).
+   */
+  readonly modifierExtension?: Extension[];
+
+  /**
+   * Index of primary sequences of amino acids linked through peptide bonds
+   * in order of decreasing length. Sequences of the same length will be
+   * ordered by molecular weight. Subunits that have identical sequences
+   * will be repeated and have sequential subscripts.
+   */
+  readonly subunit?: number;
+
+  /**
+   * The sequence information shall be provided enumerating the amino acids
+   * from N- to C-terminal end using standard single-letter amino acid
+   * codes. Uppercase shall be used for L-amino acids and lowercase for
+   * D-amino acids. Transcribed SubstanceProteins will always be described
+   * using the translated sequence; for synthetic peptide containing amino
+   * acids that are not represented with a single letter code an X should
+   * be used within the sequence. The modified amino acids will be
+   * distinguished by their position in the sequence.
+   */
+  readonly sequence?: string;
+
+  /**
+   * Length of linear sequences of amino acids contained in the subunit.
+   */
+  readonly length?: number;
+
+  /**
+   * The sequence information shall be provided enumerating the amino acids
+   * from N- to C-terminal end using standard single-letter amino acid
+   * codes. Uppercase shall be used for L-amino acids and lowercase for
+   * D-amino acids. Transcribed SubstanceProteins will always be described
+   * using the translated sequence; for synthetic peptide containing amino
+   * acids that are not represented with a single letter code an X should
+   * be used within the sequence. The modified amino acids will be
+   * distinguished by their position in the sequence.
+   */
+  readonly sequenceAttachment?: Attachment;
+
+  /**
+   * Unique identifier for molecular fragment modification based on the ISO
+   * 11238 Substance ID.
+   */
+  readonly nTerminalModificationId?: Identifier;
+
+  /**
+   * The name of the fragment modified at the N-terminal of the
+   * SubstanceProtein shall be specified.
+   */
+  readonly nTerminalModification?: string;
+
+  /**
+   * Unique identifier for molecular fragment modification based on the ISO
+   * 11238 Substance ID.
+   */
+  readonly cTerminalModificationId?: Identifier;
+
+  /**
+   * The modification at the C-terminal shall be specified.
+   */
+  readonly cTerminalModification?: string;
+}

package/dist/SubstanceReferenceInformation.d.ts

@@ -0,0 +1,386 @@
+/*
+ * Generated by @medplum/generator
+ * Do not edit manually.
+ */
+
+import { CodeableConcept } from './CodeableConcept';
+import { DocumentReference } from './DocumentReference';
+import { Extension } from './Extension';
+import { Identifier } from './Identifier';
+import { Meta } from './Meta';
+import { Narrative } from './Narrative';
+import { Quantity } from './Quantity';
+import { Range } from './Range';
+import { Reference } from './Reference';
+import { Resource } from './Resource';
+
+/**
+ * Todo.
+ */
+export interface SubstanceReferenceInformation {
+
+  /**
+   * This is a SubstanceReferenceInformation resource
+   */
+  readonly resourceType: 'SubstanceReferenceInformation';
+
+  /**
+   * The logical id of the resource, as used in the URL for the resource.
+   * Once assigned, this value never changes.
+   */
+  readonly id?: string;
+
+  /**
+   * The metadata about the resource. This is content that is maintained by
+   * the infrastructure. Changes to the content might not always be
+   * associated with version changes to the resource.
+   */
+  readonly meta?: Meta;
+
+  /**
+   * A reference to a set of rules that were followed when the resource was
+   * constructed, and which must be understood when processing the content.
+   * Often, this is a reference to an implementation guide that defines the
+   * special rules along with other profiles etc.
+   */
+  readonly implicitRules?: string;
+
+  /**
+   * The base language in which the resource is written.
+   */
+  readonly language?: string;
+
+  /**
+   * A human-readable narrative that contains a summary of the resource and
+   * can be used to represent the content of the resource to a human. The
+   * narrative need not encode all the structured data, but is required to
+   * contain sufficient detail to make it "clinically safe" for a human to
+   * just read the narrative. Resource definitions may define what content
+   * should be represented in the narrative to ensure clinical safety.
+   */
+  readonly text?: Narrative;
+
+  /**
+   * These resources do not have an independent existence apart from the
+   * resource that contains them - they cannot be identified independently,
+   * and nor can they have their own independent transaction scope.
+   */
+  readonly contained?: Resource[];
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the resource. To make the use of extensions
+   * safe and manageable, there is a strict set of governance  applied to
+   * the definition and use of extensions. Though any implementer can
+   * define an extension, there is a set of requirements that SHALL be met
+   * as part of the definition of the extension.
+   */
+  readonly extension?: Extension[];
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the resource and that modifies the
+   * understanding of the element that contains it and/or the understanding
+   * of the containing element's descendants. Usually modifier elements
+   * provide negation or qualification. To make the use of extensions safe
+   * and manageable, there is a strict set of governance applied to the
+   * definition and use of extensions. Though any implementer is allowed to
+   * define an extension, there is a set of requirements that SHALL be met
+   * as part of the definition of the extension. Applications processing a
+   * resource are required to check for modifier extensions.
+   *
+   * Modifier extensions SHALL NOT change the meaning of any elements on
+   * Resource or DomainResource (including cannot change the meaning of
+   * modifierExtension itself).
+   */
+  readonly modifierExtension?: Extension[];
+
+  /**
+   * Todo.
+   */
+  readonly comment?: string;
+
+  /**
+   * Todo.
+   */
+  readonly gene?: SubstanceReferenceInformationGene[];
+
+  /**
+   * Todo.
+   */
+  readonly geneElement?: SubstanceReferenceInformationGeneElement[];
+
+  /**
+   * Todo.
+   */
+  readonly classification?: SubstanceReferenceInformationClassification[];
+
+  /**
+   * Todo.
+   */
+  readonly target?: SubstanceReferenceInformationTarget[];
+}
+
+/**
+ * Todo.
+ */
+export interface SubstanceReferenceInformationClassification {
+
+  /**
+   * Unique id for the element within a resource (for internal references).
+   * This may be any string value that does not contain spaces.
+   */
+  readonly id?: string;
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element. To make the use of extensions
+   * safe and manageable, there is a strict set of governance  applied to
+   * the definition and use of extensions. Though any implementer can
+   * define an extension, there is a set of requirements that SHALL be met
+   * as part of the definition of the extension.
+   */
+  readonly extension?: Extension[];
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element and that modifies the
+   * understanding of the element in which it is contained and/or the
+   * understanding of the containing element's descendants. Usually
+   * modifier elements provide negation or qualification. To make the use
+   * of extensions safe and manageable, there is a strict set of governance
+   * applied to the definition and use of extensions. Though any
+   * implementer can define an extension, there is a set of requirements
+   * that SHALL be met as part of the definition of the extension.
+   * Applications processing a resource are required to check for modifier
+   * extensions.
+   *
+   * Modifier extensions SHALL NOT change the meaning of any elements on
+   * Resource or DomainResource (including cannot change the meaning of
+   * modifierExtension itself).
+   */
+  readonly modifierExtension?: Extension[];
+
+  /**
+   * Todo.
+   */
+  readonly domain?: CodeableConcept;
+
+  /**
+   * Todo.
+   */
+  readonly classification?: CodeableConcept;
+
+  /**
+   * Todo.
+   */
+  readonly subtype?: CodeableConcept[];
+
+  /**
+   * Todo.
+   */
+  readonly source?: Reference<DocumentReference>[];
+}
+
+/**
+ * Todo.
+ */
+export interface SubstanceReferenceInformationGene {
+
+  /**
+   * Unique id for the element within a resource (for internal references).
+   * This may be any string value that does not contain spaces.
+   */
+  readonly id?: string;
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element. To make the use of extensions
+   * safe and manageable, there is a strict set of governance  applied to
+   * the definition and use of extensions. Though any implementer can
+   * define an extension, there is a set of requirements that SHALL be met
+   * as part of the definition of the extension.
+   */
+  readonly extension?: Extension[];
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element and that modifies the
+   * understanding of the element in which it is contained and/or the
+   * understanding of the containing element's descendants. Usually
+   * modifier elements provide negation or qualification. To make the use
+   * of extensions safe and manageable, there is a strict set of governance
+   * applied to the definition and use of extensions. Though any
+   * implementer can define an extension, there is a set of requirements
+   * that SHALL be met as part of the definition of the extension.
+   * Applications processing a resource are required to check for modifier
+   * extensions.
+   *
+   * Modifier extensions SHALL NOT change the meaning of any elements on
+   * Resource or DomainResource (including cannot change the meaning of
+   * modifierExtension itself).
+   */
+  readonly modifierExtension?: Extension[];
+
+  /**
+   * Todo.
+   */
+  readonly geneSequenceOrigin?: CodeableConcept;
+
+  /**
+   * Todo.
+   */
+  readonly gene?: CodeableConcept;
+
+  /**
+   * Todo.
+   */
+  readonly source?: Reference<DocumentReference>[];
+}
+
+/**
+ * Todo.
+ */
+export interface SubstanceReferenceInformationGeneElement {
+
+  /**
+   * Unique id for the element within a resource (for internal references).
+   * This may be any string value that does not contain spaces.
+   */
+  readonly id?: string;
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element. To make the use of extensions
+   * safe and manageable, there is a strict set of governance  applied to
+   * the definition and use of extensions. Though any implementer can
+   * define an extension, there is a set of requirements that SHALL be met
+   * as part of the definition of the extension.
+   */
+  readonly extension?: Extension[];
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element and that modifies the
+   * understanding of the element in which it is contained and/or the
+   * understanding of the containing element's descendants. Usually
+   * modifier elements provide negation or qualification. To make the use
+   * of extensions safe and manageable, there is a strict set of governance
+   * applied to the definition and use of extensions. Though any
+   * implementer can define an extension, there is a set of requirements
+   * that SHALL be met as part of the definition of the extension.
+   * Applications processing a resource are required to check for modifier
+   * extensions.
+   *
+   * Modifier extensions SHALL NOT change the meaning of any elements on
+   * Resource or DomainResource (including cannot change the meaning of
+   * modifierExtension itself).
+   */
+  readonly modifierExtension?: Extension[];
+
+  /**
+   * Todo.
+   */
+  readonly type?: CodeableConcept;
+
+  /**
+   * Todo.
+   */
+  readonly element?: Identifier;
+
+  /**
+   * Todo.
+   */
+  readonly source?: Reference<DocumentReference>[];
+}
+
+/**
+ * Todo.
+ */
+export interface SubstanceReferenceInformationTarget {
+
+  /**
+   * Unique id for the element within a resource (for internal references).
+   * This may be any string value that does not contain spaces.
+   */
+  readonly id?: string;
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element. To make the use of extensions
+   * safe and manageable, there is a strict set of governance  applied to
+   * the definition and use of extensions. Though any implementer can
+   * define an extension, there is a set of requirements that SHALL be met
+   * as part of the definition of the extension.
+   */
+  readonly extension?: Extension[];
+
+  /**
+   * May be used to represent additional information that is not part of
+   * the basic definition of the element and that modifies the
+   * understanding of the element in which it is contained and/or the
+   * understanding of the containing element's descendants. Usually
+   * modifier elements provide negation or qualification. To make the use
+   * of extensions safe and manageable, there is a strict set of governance
+   * applied to the definition and use of extensions. Though any
+   * implementer can define an extension, there is a set of requirements
+   * that SHALL be met as part of the definition of the extension.
+   * Applications processing a resource are required to check for modifier
+   * extensions.
+   *
+   * Modifier extensions SHALL NOT change the meaning of any elements on
+   * Resource or DomainResource (including cannot change the meaning of
+   * modifierExtension itself).
+   */
+  readonly modifierExtension?: Extension[];
+
+  /**
+   * Todo.
+   */
+  readonly target?: Identifier;
+
+  /**
+   * Todo.
+   */
+  readonly type?: CodeableConcept;
+
+  /**
+   * Todo.
+   */
+  readonly interaction?: CodeableConcept;
+
+  /**
+   * Todo.
+   */
+  readonly organism?: CodeableConcept;
+
+  /**
+   * Todo.
+   */
+  readonly organismType?: CodeableConcept;
+
+  /**
+   * Todo.
+   */
+  readonly amountQuantity?: Quantity;
+
+  /**
+   * Todo.
+   */
+  readonly amountRange?: Range;
+
+  /**
+   * Todo.
+   */
+  readonly amountString?: string;
+
+  /**
+   * Todo.
+   */
+  readonly amountType?: CodeableConcept;
+
+  /**
+   * Todo.
+   */
+  readonly source?: Reference<DocumentReference>[];
+}