@datagrok/sequence-translator 1.0.16 → 1.1.0

package/src/tests/smiles-tests.ts

@@ -1,458 +1,33 @@
-import {category, expect, test} from '@datagrok-libraries/utils/src/test';
-import {sequenceToSmiles} from '../structures-works/from-monomers';
-import {SYNTHESIZERS} from '../structures-works/map';
-
-category('sequence-translator', () => {
-  // test('AGGTCCTCTTGACTTAGGCC', async () => {
-  //   const expected = 'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)C[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=C(C)C(=O)NC2(=O))C[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))C[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))C[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=C(C)C(=O)NC2(=O))C[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))C[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=C(C)C(=O)NC2(=O))C[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=C(C)C(=O)NC2(=O))C[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)C[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))C[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=C(C)C(=O)NC2(=O))C[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=C(C)C(=O)NC2(=O))C[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)C[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))C[C@@H]1OP(=O)(O)OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))C[C@@H]1O';
-
-  //   expect(sequenceToSmiles('AGGTCCTCTTGACTTAGGCC', false, SYNTHESIZERS.RAW_NUCLEOTIDES), expected);
-  // });
-
-  // test('invabasic/galnac1', async () => {
-  //   const expected = 'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(O)' +
-  //   'OCC(O)CNC(=O)CCCC(=O)NC(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)' +
-  //   '(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)' +
-  //   '(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)';
-  //   expect(sequenceToSmiles('(invabasic)sgg(invabasic)(GalNAc-2-JNJ)', false, SYNTHESIZERS.AXOLABS), expected);
-  // });
-
-  // test('invabasic/galnac2', async () => {
-  //   const expected = 'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(O)' +
-  //   'OCC(O)CNC(=O)CCCC(=O)NC(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)' +
-  //   '(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)' +
-  //   '(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)';
-  //   expect(sequenceToSmiles('(invabasic)sgsg(invabasic)(GalNAc-2-JNJ)', false, SYNTHESIZERS.AXOLABS), expected);
-  // });
-
-  // test('invabasic/galnac3', async () => {
-  //   const expected = 'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(S)' +
-  //   'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(O)' +
-  //   'OCC(O)CNC(=O)CCCC(=O)NC(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)' +
-  //   '(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)' +
-  //   '(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)';
-  //   expect(sequenceToSmiles('(invabasic)sggs(invabasic)(GalNAc-2-JNJ)', false, SYNTHESIZERS.AXOLABS), expected);
-  // });
-
-  // test('invabasic/galnac4', async () => {
-  //   const expected = 'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(S)' +
-  //   'OCC(O)CNC(=O)CCCC(=O)NC(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)' +
-  //   '(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)' +
-  //   '(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)';
-  //   expect(sequenceToSmiles('(invabasic)sgg(invabasic)s(GalNAc-2-JNJ)', false, SYNTHESIZERS.AXOLABS), expected);
-  // });
-
-  test('usCfCfUfGfAf', async () => {
-    const expected = 'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(S)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](F)[C@@H]1O';
-    expect(sequenceToSmiles('usCfCfUfGfAf', false, SYNTHESIZERS.AXOLABS), expected);
-  });
-
-  test('usAfsusgsgsg', async () => {
-    const expected = 'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(S)' +
-    'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](F)[C@@H]1OP(=O)(S)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(S)' +
-    'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(S)' +
-    'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(S)' +
-    'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1O';
-    expect(sequenceToSmiles('usAfsusgsgsg', false, SYNTHESIZERS.AXOLABS), expected);
-  });
-
-  test('UfUfUfsCfsuacg', async () => {
-    const expected = 'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](F)[C@@H]1OP(=O)(S)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](F)[C@@H]1OP(=O)(S)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1O';
-    expect(sequenceToSmiles('UfUfUfsCfsuacg', false, SYNTHESIZERS.AXOLABS), expected);
-  });
-
-  test('susususauasu', async () => {
-    const expected = 'OP(=O)(S)OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(S)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(S)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(S)' +
-    'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(S)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1O';
-    expect(sequenceToSmiles('susususauasu', false, SYNTHESIZERS.AXOLABS), expected);
-  });
-
-  test('CfGfCfsGfsCf', async () => {
-    const expected = 'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](F)[C@@H]1OP(=O)(S)' +
-    'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](F)[C@@H]1OP(=O)(S)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](F)[C@@H]1O';
-    expect(sequenceToSmiles('CfGfCfsGfsCf', false, SYNTHESIZERS.AXOLABS), expected);
-  });
-
-  test('acacacsacsac', async () => {
-    const expected = 'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(S)' +
-    'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(S)' +
-    'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1O';
-    expect(sequenceToSmiles('acacacsacsac', false, SYNTHESIZERS.AXOLABS), expected);
-  });
-
-  test('cccgggusug', async () => {
-    const expected =
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(S)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1O';
-    expect(sequenceToSmiles('cccgggusug', false, SYNTHESIZERS.AXOLABS), expected);
-  });
-
-  test('UfAfCfGfGfCfAfUf', async () => {
-    const expected =
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](F)[C@@H]1O';
-    expect(sequenceToSmiles('UfAfCfGfGfCfAfUf', false, SYNTHESIZERS.AXOLABS), expected);
-  });
-
-  // test('(invabasic)sucuCfuUf', async () => {
-  //   const expected =
-  //   'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](F)[C@@H]1O';
-  //   expect(sequenceToSmiles('(invabasic)sucuCfuUf', false, SYNTHESIZERS.AXOLABS), expected);
-  // });
-
-  // test('(invabasic)sAfgcugUf', async () => {
-  //   const expected =
-  //   'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](F)[C@@H]1O';
-  //   expect(sequenceToSmiles('(invabasic)sAfgcugUf', false, SYNTHESIZERS.AXOLABS), expected);
-  // });
-
-  test('(invabasic)cuCfuUfsc', async () => {
-    const expected =
-    'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](F)[C@@H]1OP(=O)(S)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1O';
-    expect(sequenceToSmiles('(invabasic)cuCfuUfsc', false, SYNTHESIZERS.AXOLABS), expected);
-  });
-
-  // test('(invabasic)scususu(GalNAc-2-JNJ)', async () => {
-  //   const expected =
-  //   'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OCC(O)CNC(=O)CCCC(=O)NC(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)' +
-  //   '(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)' +
-  //   '(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)';
-  //   expect(sequenceToSmiles('(invabasic)scususu(GalNAc-2-JNJ)', false, SYNTHESIZERS.AXOLABS), expected);
-  // });
-
-  test('(invabasic)usAfsucuCfuUfAfgcugUfgCfacususu', async () => {
-    const expected =
-    'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(S)' +
-    'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](F)[C@@H]1OP(=O)(S)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(S)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(S)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1O';
-    expect(sequenceToSmiles('(invabasic)usAfsucuCfuUfAfgcugUfgCfacususu', false, SYNTHESIZERS.AXOLABS), expected);
-  });
-
-  test('(invabasic)asacgGfuGfCfAfacucuauuca', async () => {
-    const expected =
-    'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(S)' +
-    'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](F)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-    'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1O';
-    expect(sequenceToSmiles('(invabasic)asacgGfuGfCfAfacucuauuca', false, SYNTHESIZERS.AXOLABS), expected);
-  });
-
-  // test('(invabasic)scsgguGfcAfAfCfucuauucuga', async () => {
-  //   const expected =
-  //   'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1O';
-  //   expect(sequenceToSmiles('(invabasic)scsgguGfcAfAfCfucuauucuga', false, SYNTHESIZERS.AXOLABS), expected);
-  // });
-
-  // test('(invabasic)scsaacUfcUfAfUfucuggacuua', async () => {
-  //   const expected =
-  //   'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1O';
-  //   expect(sequenceToSmiles('(invabasic)scsaacUfcUfAfUfucuggacuua', false, SYNTHESIZERS.AXOLABS), expected);
-  // });
-
-  // test('(invabasic)sasacuCfuAfUfUfcuggacuuua', async () => {
-  //   const expected =
-  //   'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1O';
-  //   expect(sequenceToSmiles('(invabasic)sasacuCfuAfUfUfcuggacuuua', false, SYNTHESIZERS.AXOLABS), expected);
-  // });
-
-  // test('(invabasic)usAfscug(invabasic)(GalNAc-2-JNJ)', async () => {
-  //   const expected = 'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](F)[C@@H]1OP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(O)' +
-  //   'OCC(O)CNC(=O)CCCC(=O)NC(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)' +
-  //   '(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)' +
-  //   '(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)';
-  //   expect(sequenceToSmiles('(invabasic)usAfscug(invabasic)(GalNAc-2-JNJ)', false, SYNTHESIZERS.AXOLABS), expected);
-  // });
-
-  // test('(invabasic)sasuaaCfcUf(GalNAc-2-JNJ)', async () => {
-  //   const expected = 'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OCC(O)CNC(=O)CCCC(=O)NC(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)' +
-  //   '(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)' +
-  //   '(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)';
-  //   expect(sequenceToSmiles('(invabasic)sasuaaCfcUf(GalNAc-2-JNJ)', false, SYNTHESIZERS.AXOLABS), expected);
-  // });
-
-  // test('(invabasic)sasuaaCfcUfCfUfuguaguuaua(GalNAc-2-JNJ)', async () => {
-  //   const expected = 'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OCC(O)CNC(=O)CCCC(=O)NC(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)' +
-  //   '(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)' +
-  //   '(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)';
-  //   expect(sequenceToSmiles('(invabasic)sasuaaCfcUfCfUfuguaguuaua(GalNAc-2-JNJ)', false, SYNTHESIZERS.AXOLABS),
-  //     expected);
-  // });
-
-  // test('(invabasic)scsaucacguUfGfCfagccgucuua(invabasic)(GalNAc-2-JNJ)', async () => {
-  //   const expected = 'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(O)' +
-  //   'OCC(O)CNC(=O)CCCC(=O)NC(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)' +
-  //   '(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)' +
-  //   '(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)';
-  //   expect(sequenceToSmiles('(invabasic)scsaucacguUfGfCfagccgucuua(invabasic)(GalNAc-2-JNJ)',
-  //     false, SYNTHESIZERS.AXOLABS), expected);
-  // });
-
-  // test('(invabasic)susguuUfgCfCfUfacaucuacua(GalNAc-2-JNJ)', async () => {
-  //   const expected = 'O[C@@H]1C[C@@H]O[C@H]1COP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(S)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=C(N)NC(=O)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](F)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(N)=NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C=CC(=O)NC2(=O))[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OC[C@H]1O[C@@H](N2C3N=CN=C(N)C=3N=C2)[C@H](OC)[C@@H]1OP(=O)(O)' +
-  //   'OCC(O)CNC(=O)CCCC(=O)NC(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)' +
-  //   '(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)' +
-  //   '(COCCC(=O)NCCCNC(=O)CCCCOC2OC(CO)C(O)C(O)C2NC(=O)C)';
-  //   expect(sequenceToSmiles('(invabasic)susguuUfgCfCfUfacaucuacua(GalNAc-2-JNJ)', false, SYNTHESIZERS.AXOLABS),
-  //     expected);
-  // });
+/* Do not change these import lines to match external modules in webpack configuration */
+import * as grok from 'datagrok-api/grok';
+import * as ui from 'datagrok-api/ui';
+import * as DG from 'datagrok-api/dg';
+
+import {before, category, expect, test} from '@datagrok-libraries/utils/src/test';
+import {DEFAULT_FORMATS} from '../model/const';
+import {getJsonData} from '../model/data-loading-utils/json-loader';
+import {axolabsToSmiles} from './const';
+import {_package} from '../package';
+import {SequenceToMolfileConverter} from '../model/sequence-to-structure-utils/sequence-to-molfile';
+
+function getSmiles(strand: string, format: string): string {
+  const molfile = (new SequenceToMolfileConverter(strand, false, format)).convert();
+  return DG.chem.convert(molfile, DG.chem.Notation.MolBlock, DG.chem.Notation.Smiles);
+}
+
+const AXOLABS = DEFAULT_FORMATS.AXOLABS;
+
+category('Axolabs to smiles', () => {
+  before(async () => {
+    await getJsonData();
+    await _package.initMonomerLib();
+  });
+
+  for (const strand of Object.keys(axolabsToSmiles)) {
+    test(`${strand} to SMILES`, async () => {
+      const expected = axolabsToSmiles[strand];
+      const result = getSmiles(strand, AXOLABS);
+      expect(result, expected);
+    });
+  }
 });

package/src/view/const/main-tab.ts

@@ -0,0 +1,3 @@
+export const DEFAULT_INPUT = 'fAmCmGmAmCpsmU';
+export const SEQUENCE_COPIED_MSG = 'Copied';
+export const SEQ_TOOLTIP_MSG = 'Copy sequence';

package/src/view/const/view.ts

@@ -0,0 +1,10 @@
+/* Do not change these import lines to match external modules in webpack configuration */
+import * as grok from 'datagrok-api/grok';
+import * as ui from 'datagrok-api/ui';
+import * as DG from 'datagrok-api/dg';
+
+export const MAIN_TAB = 'SEQUENCE';
+export const AXOLABS_TAB = 'PATTERN';
+export const SDF_TAB = 'DUPLEX';
+
+export const DEFAULT_AXOLABS_INPUT = 'Afcgacsu';

package/src/view/css/axolabs-tab.css

@@ -0,0 +1 @@
+/* Naming convention: class names should begin with st and tab name (main, axo, sdf) to avoid naming collitions */

package/src/view/css/colored-text-input.css

@@ -0,0 +1,27 @@
+.colored-text-input > textarea {
+  width: 100%;
+  -webkit-text-fill-color: transparent;
+  background-color: transparent;
+  position: relative;
+  z-index: 1;
+  resize: none;
+  height: 22px; /* Fine tuned value to avoid "jumping" of the textarea upon autoresize */
+}
+
+.colored-text-input > div {
+  /* The values here are fine tuned to those of the ui.input textarea in order
+   * to achieve precise overlap */
+  overflow: auto;
+  position: absolute;
+  pointer-events: none;
+  cursor: text;
+  z-index: 0;
+  max-width: 100%;
+  padding: 2px;
+  line-height: normal;
+  font-family: 'Roboto Mono', 'Roboto Mono Local', monospace;
+  font-size: 12px;
+  color: transparent;
+  white-space: pre-wrap;
+  word-wrap: break-word;
+}

package/src/view/css/main-tab.css

@@ -0,0 +1,46 @@
+/* Naming convention: class names should begin with st and tab name (main, axo, sdf) to avoid naming collitions */
+.st-main-input-table {
+  width: 100%;
+}
+
+.st-main-input-table td:has(textarea) {
+  width: 100%;
+  padding-right: 20px;
+}
+
+.st-main-input-table td:has(select) {
+  min-width: 120px;
+  vertical-align: top;
+}
+
+.st-main-output-table {
+  margin-top: 20px;
+  margin-right: 20px;
+  margin-bottom: 10px;
+}
+
+.st-main-output-table table {
+  width: 100%;
+  table-layout: fixed;
+}
+
+/* .st-main-output-table table tbody tr td { */
+/*   max-width: 20%; */
+/* } */
+
+.st-main-output-table td {
+  padding-top: 6px;
+  padding-bottom: 6px;
+}
+.st-main-output-table tr:nth-child(even) {
+  background-color: var(--grey-1);
+}
+
+.st-main-output-table td:nth-child(odd) {
+  width: 120px;
+  vertical-align: top;
+}
+
+.st-main-output-table td a {
+  overflow-wrap: break-word;
+}

package/src/view/css/sdf-tab.css

@@ -0,0 +1,39 @@
+/* Naming convention: class names should begin with st and tab name (main, axo, sdf) to avoid naming collitions */
+
+.st-sdf-body {
+  padding-right: 20px;
+}
+
+.st-sdf-input-form {
+  text-align: right;
+  vertical-align: top;
+  min-width: 95px;
+}
+
+.st-sdf-direction-choice label {
+  min-width: 100px;
+  float: right;
+}
+
+.st-sdf-direction-choice div {
+  justify-content: right;
+}
+
+.st-sdf-text-input-td { /* Style for td containing textarea */
+  width: 100%;
+}
+
+.st-sdf-mol-img {
+  margin-right: 30px;
+  float: right;
+}
+
+.st-sdf-bool-button-block {
+  justify-content: right;
+  margin-bottom: 10px;
+}
+
+.st-sdf-bottom {
+  flex-direction: row-reverse;
+  padding-top: 20px;
+}

package/src/view/monomer-lib-viewer/viewer.ts

@@ -0,0 +1,22 @@
+/* Do not change these import lines to match external modules in webpack configuration */
+import * as grok from 'datagrok-api/grok';
+import * as ui from 'datagrok-api/ui';
+import * as DG from 'datagrok-api/dg';
+
+import {drawZoomedInMolecule} from '../utils/draw-molecule';
+import {MonomerLibWrapper} from '../../model/monomer-lib/lib-wrapper';
+
+export class MonomerLibViewer {
+  static async view(): Promise<void> {
+    const table = MonomerLibWrapper.getInstance().getTableForViewer();
+    table.name = 'Monomer Library';
+    const view = grok.shell.addTableView(table);
+    view.grid.props.allowEdit = false;
+    const onDoubleClick = view.grid.onCellDoubleClick;
+    onDoubleClick.subscribe(async (gridCell: DG.GridCell) => {
+      const molfile = gridCell.cell.value;
+      if (gridCell.tableColumn?.semType === 'Molecule')
+        await drawZoomedInMolecule(molfile);
+    });
+  }
+}